LOCUS       NZ_BMUQ01000015        20912 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces mirabilis strain JCM 4551 sequence15, whole genome
            shotgun sequence.
ACCESSION   NZ_BMUQ01000015
VERSION     NZ_BMUQ01000015.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces mirabilis
  ORGANISM  Streptomyces mirabilis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 268352)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 117X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650275.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:52:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,392
            CDSs (total)                      :: 10,311
            Genes (coding)                    :: 9,898
            CDSs (with protein)               :: 9,898
            Genes (RNA)                       :: 81
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 414
            CDSs (without protein)            :: 413
            Pseudo Genes (ambiguous residues) :: 0 of 414
            Pseudo Genes (frameshifted)       :: 172 of 414
            Pseudo Genes (incomplete)         :: 329 of 414
            Pseudo Genes (internal stop)      :: 40 of 414
            Pseudo Genes (multiple problems)  :: 115 of 414
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:21:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 169008
            Orig. end                         :: 189920
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMUQ01000015.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20912
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20912
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20912
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10912](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10912)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(466..481)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 18.35"
                     /tool="antismash"
     gene            670..1041
                     /locus_tag="IE289_RS32210"
                     /old_locus_tag="GCM10010317_066490"
     CDS             670..1041
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030021.1"
                     /locus_tag="IE289_RS32210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_066490"
                     /product="WhiB family transcriptional regulator"
                     /protein_id="WP_075028724.1"
                     /transl_table=11
                     /translation="MLQPPHQSLQVAAVPAQRAPVRDRDQEAPWHTEAVCRRDEAGLFF
                     APSKEPTAARLSREEAAKRVCARCPVMVECREHALLQPEPYGVWGGLTAAERRVVLARR
                     RRRDLELKKAARGTIAAAG"
     gene            complement(1214..2245)
                     /gene="glpX"
                     /locus_tag="IE289_RS32215"
                     /old_locus_tag="GCM10010317_066500"
     CDS             complement(1214..2245)
                     /EC_number="3.1.3.11"
                     /GO_function="GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA]"
                     /GO_process="GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /gene="glpX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019522337.1"
                     /locus_tag="IE289_RS32215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_066500"
                     /product="class II fructose-bisphosphatase"
                     /protein_id="WP_099920840.1"
                     /transl_table=11
                     /translation="MTEHHLPSELEVPSEAPDRNLALELVRVTEAAAMAAGRWVGRGDK
                     NGADGAAVRAMRTLVSTVSMNGVVVIGEGEKDEAPMLFNGERVGDGTGPECDIAVDPID
                     GTTLTAKGMSNAIAVLAAADRGTMFDPSAVFYMDKLVTGPEAADFVDINAPVSVNIRRV
                     AKAKKSSPEDVTVVILDRPRHEGIIKEIRETGARIKLISDGDVAGSILALREGTGIDLL
                     LGIGGTPEGIISACAVKCLGGTIQGKLWPKDDEERQRAVDAGHDLDRVLLTDDLVSGEN
                     VFFVATGITDGELLRGVRYRAETATTESIVMRSKSGTVRQIRSEHRLSKLRAYSAIDFD
                     RAK"
     misc_feature    complement(2298..2318)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: medium, score: 26.25"
                     /tool="antismash"
     gene            2371..2889
                     /locus_tag="IE289_RS32220"
                     /old_locus_tag="GCM10010317_066510"
     CDS             2371..2889
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010984644.1"
                     /locus_tag="IE289_RS32220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_066510"
                     /product="DUF4245 domain-containing protein"
                     /protein_id="WP_099920839.1"
                     /transl_table=11
                     /translation="MAGTKGKQSVRDMLLSLGLIGLMAGVIYIFIPHDDSAPPLKRVDY
                     RVELLTARRAASYPVAAPVGLPTAWKATSVRYDGTEFDAWHLGFHDPDGQYVAIEQSTQ
                     PAAVFIDSASQGAKETKATQRIGDATWQRYEGDKYDALVLRAKGATTVVTGTASFGQLT
                     KMAEALKTS"
     gene            complement(3004..3594)
                     /locus_tag="IE289_RS32225"
                     /old_locus_tag="GCM10010317_066520"
     CDS             complement(3004..3594)
                     /EC_number="1.1.1.298"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1159: dihydropteridine reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136824.1"
                     /locus_tag="IE289_RS32225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_066520"
                     /product="malonic semialdehyde reductase"
                     /protein_id="WP_099920838.1"
                     /sec_met_domain="PF00881 (E-value: 1.6e-18, bitscore: 61.3,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLVLDPAAQDLLFREARTANTFTDEPVTDEQVQAIYDLVKYGPT
                     AFNQSPLRITLVRSAEARERLVQHMAEGNQPKTATAPLVAILSADNEFHEELPALFPHF
                     PQAKDVFFAERPAREGAASLNAALQAAYFIIGVRAAGLAAGPMTGLDFAGVQKEFLDDD
                     HTPLMVVNIGKPGEDAWFPRSPRLEFDQVITTV"
     misc_feature    3693..3708
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     gene            complement(3855..4112)
                     /locus_tag="IE289_RS32230"
                     /old_locus_tag="GCM10010317_066530"
     CDS             complement(3855..4112)
                     /EC_number="3.1.11.6"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674708.1"
                     /locus_tag="IE289_RS32230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_066530"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_190172262.1"
                     /transl_table=11
                     /translation="MTSKVDEALGYEQARDELIEVVRRLEAGGTTLEESLALWERGEEL
                     AKVCRRWLEGARARLDAALAEEESESEDGDGHGDGGRDSG"
     gene            complement(4122..5330)
                     /gene="xseA"
                     /locus_tag="IE289_RS32235"
                     /old_locus_tag="GCM10010317_066540"
     CDS             complement(4122..5330)
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019058475.1"
                     /locus_tag="IE289_RS32235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_066540"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_190172263.1"
                     /transl_table=11
                     /translation="MALNTSADAPLPVGEVSRLIGGWIDRLGAVWVEGQITQLSRRPGA
                     GVVFLTLRDPSYDISVSVTCYRQVFEAVADVVSEGARVVVLAKPEWYAPRGQLSLRATE
                     IKPVGVGELLARLEQLKKSLASEGLFAADRKKALPFLPQLIGLVCGRASAAERDVLENA
                     RHRWPAVRFEVRNVPVQGVHAVPQVVQAVKELDALDTVDVIIVARGGGSVEDLLPFSDE
                     QLVRAVAACRTPVVSAIGHEPDNPLLDFVADLRASTPTDAAKKVVPDVGEEYERVRSLR
                     DRARRSVQAFIDREERGLAHALARPSIEDPHRMVDERADQVTALLDRGRRTLGHLLDRA
                     DSELTHTHARVVALSPAATLQRGYAVLQKTDGHVVRDPDEVAAGEALRARVAEGEFTVR
                     VDA"
     gene            complement(<5445..>5841)
                     /locus_tag="IE289_RS51985"
                     /pseudo=""
     CDS             complement(<5445..5841)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018519013.1"
                     /locus_tag="IE289_RS51985"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="amino acid permease"
                     /pseudo=""
                     /transl_table=11
                     /translation="MHNLVAASKAIGAAFAALAGQAAAGRLVFAVARDRRLPRALSKTD
                     SGVPRAAPLCAAFITLVAAVWAARRDDGLDRLVSVVDIGALTAFTLPHASVVGGVRTAS
                     GRARGVVAACPGPRDRGRGHRCRDRGGV"
     misc_feature    5797..5806
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     gene            5909..6934
                     /locus_tag="IE289_RS32245"
                     /old_locus_tag="GCM10010317_066550"
     CDS             5909..6934
                     /EC_number="1.17.7.4"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051745 - 4-hydroxy-3-methylbut-2-enyl
                     diphosphate reductase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992702.1"
                     /locus_tag="IE289_RS32245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_066550"
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="WP_099920835.1"
                     /transl_table=11
                     /translation="MGAMTASPGRRVLLAAPRGYCAGVDRAVIAVEKALEQYGAPIYVR
                     HEIVHNKYVVQTLEKKGAIFVEQTAEVPEGSIVMFSAHGVAPVVHDEAAAGKLATIDAT
                     CPLVTKVHKEAVRFANEDFDILLIGHEGHEEVIGTSGEAPDHITLVDGPEDVAKVEVRD
                     PSKVVWLSQTTLSVDETMETVDALKEKFPQLISPPSDDICYATQNRQLAVKRMGEEADL
                     VIVVGSRNSSNSVRLVEVAKLAGARAAYLVDFADEIEEGWLEGVTTVGVTSGASVPEVL
                     VEQVLEWLSARDFEDVEIVKAAEESITFSLPKELRRDLRAEAAALVEQRTAAGSAAPSE
                     K"
     gene            6964..7710
                     /gene="ppgK"
                     /locus_tag="IE289_RS32250"
                     /old_locus_tag="GCM10010317_066560"
     CDS             6964..7710
                     /EC_number="2.7.1.63"
                     /GO_function="GO:0004340 - glucokinase activity [Evidence
                     IEA]"
                     /GO_function="GO:0047330 - polyphosphate-glucose
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /gene="ppgK"
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983839.1"
                     /locus_tag="IE289_RS32250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_066560"
                     /product="polyphosphate--glucose phosphotransferase"
                     /protein_id="WP_190172265.1"
                     /transl_table=11
                     /translation="MQIFGVDIGGSGIKGAPVDLDRGELTEERYKVLTPHPATPDAVAD
                     GVKEVVGHFGWTGPVGITFPGVVTGGATIRTAANVDKAWIDTDARALLGERLGGLPVTV
                     LNDADAAGVAEMQFGAGRDRRGTVLLLTFGTGIGSALFADGELVLNTELGHLELNGHDA
                     EKRASTKAKEDHELTWEQWAHRVQKYLAHVEMLFSPELFIIGGGVSRKADKFLPLIEGI
                     KAEIVPAQLQNNAGIVGAAMRAAKSA"
     gene            complement(7865..8296)
                     /locus_tag="IE289_RS32255"
                     /old_locus_tag="GCM10010317_066570"
     CDS             complement(7865..8296)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006378272.1"
                     /locus_tag="IE289_RS32255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_066570"
                     /product="DUF6542 domain-containing protein"
                     /protein_id="WP_373306521.1"
                     /transl_table=11
                     /translation="MPNPRLTGLGGGLFCGATMFALACLDQLLFGASLVVYGVLFLPVC
                     ALTALWVRRGDIVTAPVVVPIAFAFGLLPVADGGGGIGGELMGLVTALATQAGWLYGGT
                     LIAGVITTVRKVRLMTRRAAQRRAAREPRQEIRPRRRPT"
     gene            8626..9714
                     /gene="ychF"
                     /locus_tag="IE289_RS32260"
                     /old_locus_tag="GCM10010317_066580"
     CDS             8626..9714
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ychF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019058470.1"
                     /locus_tag="IE289_RS32260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_066580"
                     /product="redox-regulated ATPase YchF"
                     /protein_id="WP_099920832.1"
                     /transl_table=11
                     /translation="MSLTIGIVGLPNVGKSTLFNALTKNDVLAANYPFATIEPNVGVVG
                     VPDARLTKLAEIFGSQRVLPATVDFVDIAGIVKGASEGEGLGNKFLANIRESDAICQVI
                     RAFKDENVVHVDGKVSPKDDIETINTELILADLQTIEKVLPRLQKESRIKKDIAPKVAA
                     VEAAKEILEKGDTLFSQGIVQGSGNEELLHDLHLLTTKPFLYVFNVDEDELVDEDFKAE
                     QRTLVAPAEAIFLNAKLEQDLAELDEEDAMELLESVGAEEPGLATLARVGFDTLGLQTY
                     LTAGPKESRAWTIKKGDTAPEAAGVIHTDFQKGFIKAEVISFEDLVDTGSVAEARAKGK
                     ARMEGKDYVMQDGDVVEFRFNV"
     misc_feature    8671..8684
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     misc_feature    9719..9735
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.94"
                     /tool="antismash"
     gene            9752..>9960
                     /locus_tag="IE289_RS53245"
                     /pseudo=""
     CDS             9752..>9960
                     /GO_component="GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0097351 - toxin sequestering activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010468398.1"
                     /locus_tag="IE289_RS53245"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /pseudo=""
                     /transl_table=11
                     /translation="MQVKWGRLFREPTPALFPLIKRSTTITRPSRSSPSTATPCLSRPR
                     TTRRCARARTCCALRPTRADCTRR"
     gene            complement(10001..10912)
                     /locus_tag="IE289_RS32270"
                     /old_locus_tag="GCM10010317_066590"
     CDS             complement(10001..10912)
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604592.1"
                     /locus_tag="IE289_RS32270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_066590"
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_190172267.1"
                     /sec_met_domain="phytoene_synt (E-value: 6.1e-23, bitscore:
                     75.3, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 3.4e-12,
                     bitscore: 40.1, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTWKRSLTAAGVREPELRNDYDDGRRLVARFRRSSYLAARLLLP
                     PSMLPHVVAATAVMHHGDNVLDTGPKPQRIAAWASWERRVRKALETGVADDPLTRTLLH
                     TVAAYPRLRGVVEEYLSTAGAELEFTGFVSEADYQAYVDAYSLPAFMLVAVLLGPEDDD
                     GRYRAMCRTLIDGSQRLDFVNDLAEDITEGRPSIPAQTLARFSVTVADLAAGHEPPGLR
                     LLVEHEVRAARAALEAARELPTQVSAPGQALLNAFVEIELLTADAALARGAALLHGSAS
                     PPLLGTLRILRNARRAARSARR"
     gene            complement(10918..11073)
                     /locus_tag="IE289_RS32275"
     CDS             complement(10918..11073)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE289_RS32275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_190172268.1"
                     /transl_table=11
                     /translation="MAELLITAGHMLLGPDDEHVEDAAVLIAGNTIAAAGRRTHVQAQA
                     GLCPGR"
     gene            complement(11066..12271)
                     /locus_tag="IE289_RS32280"
                     /old_locus_tag="GCM10010317_066600"
     CDS             complement(11066..12271)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042915.1"
                     /locus_tag="IE289_RS32280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_066600"
                     /product="MAB_1171c family putative transporter"
                     /protein_id="WP_190172269.1"
                     /transl_table=11
                     /translation="MIALALVVGTVFVLTLGWKIRQFVTSPHDAPLRAVTLCLASAAAS
                     FGLALPPAAKAIRSVGGSGAPRLVQNAFAFAMVFWLMCFYLYSATDPQRGRIRARRETL
                     PLGLTLLGTSLATIAAAGHDTGGSYDSVDMRVSALATFYLLADLYLVYALTAALLWTCR
                     YARASPRPLSVGLWLMASALSGIAAASAIRAALTVIRWHGGAVAPAVTKFSGHIIAVAI
                     PLFLIGAGYPAALTRLSVMRLRRQRRSMYHRLHPLWSLLHEAYPQHALHQNRARPWGLL
                     RRPRAVDRHYYRRAIECRDGLVRISPYLGQAEETVTDLSESSADLLADQLCAALEAQAE
                     GGEAPYGAVAVAVPQAQGLDADVRQLVMLSDALLRRTSHPAQQDQQDQQDQHKEHHRSR
                     RG"
     gene            complement(12268..12657)
                     /locus_tag="IE289_RS32285"
                     /old_locus_tag="GCM10010317_066610"
     CDS             complement(12268..12657)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018848082.1"
                     /locus_tag="IE289_RS32285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_066610"
                     /product="hypothetical protein"
                     /protein_id="WP_229889298.1"
                     /transl_table=11
                     /translation="MPYPLPVPGPFGVWISTRSADYILYQRETSKVHQDHIILHEVGHI
                     MADHRSTVSGDEIWQQLMPDISVDVIKKTLLRTSYDEEHEREAELVATIILEWASVLDY
                     VDSSSSVDPSVDRVQSALGDRQGWQ"
     gene            complement(12999..13451)
                     /locus_tag="IE289_RS32290"
                     /old_locus_tag="GCM10010317_066620"
     CDS             complement(12999..13451)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003980830.1"
                     /locus_tag="IE289_RS32290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_066620"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_190172271.1"
                     /transl_table=11
                     /translation="MAEGANRSLADKLNELFANVRPDVGHEYSNEQVAAAIRGTGVTIS
                     QSYIWQLRKGVKNNPTLKHLEALAGFFGVPAAYFLDTETNNRVAEQLKLLAETQARLAD
                     SSPESDVKLMAMRAGHLSGERRKQVMDLLDVVYRLEQAEAKQQDTQ"
     gene            13665..14714
                     /locus_tag="IE289_RS32295"
                     /old_locus_tag="GCM10010317_066630"
     CDS             13665..14714
                     /codon_start=1
                     /gene_functions="regulatory (extras) StrR_like: StrR-like
                     pathway specfic regulators"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE289_RS32295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010317_066630"
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="WP_190172272.1"
                     /transl_table=11
                     /translation="MSATSVTGEIAEGAIVPATPEEIGGVLDRAVERVPIRLLSGVSSP
                     RTSGADDRHVRALAELDVPLPPVVVHRPTMRVLDGVHRIRAAELRGESDVEVRYFDGGE
                     EEAFLLAVQLNSAQGKPLSFDDRTAAALRIVASHSHWSDRRIASVTCLSAKTVAVLRGC
                     STEDGPQSNKRVGLDGRARPLHPAEGRLLAGELLAKDPHLSLRELARRAGTSVATASDV
                     RQRFLQGRELLPTRLRGGGPPEDGGPRSRRHDDGGGSSGTGVPGGFSGGGRPGSPALLE
                     SLRRDPSVRHTESGRRFLQLLSIHPTGPSEWQKLVRDVPAHRADVVARIARDYAEAWLH
                     VARTLESNS"
     misc_feature    14250..14252
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(14832..14846)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.74"
                     /tool="antismash"
     misc_feature    complement(14849..14858)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.11"
                     /tool="antismash"
     gene            14873..15529
                     /locus_tag="IE289_RS32300"
                     /old_locus_tag="GCM10010317_066640"
     CDS             14873..15529
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04032.1"
                     /locus_tag="IE289_RS32300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_066640"
                     /product="sporulation delaying protein family toxin"
                     /protein_id="WP_190172273.1"
                     /transl_table=11
                     /translation="MRLKKPLIGAVLTATMVAGVAGTASAHTQAPHTTPAAAAEAAQGY
                     SDSDVVAFLVFGQGKAAEDHPELAQQIRSRRSDASVTPAQLSYLMAKLHQADPAFHTKV
                     TKAVQAKDPFVVQQGMVALNDDLKAAIASDRKAKTLNSADIARPNGWVWTKSNIVTVAN
                     VAAGINIAAGTNVAAGAEVVVVVVIAPAAASYGFDLKQSDQLDENDFVAAVTSAL"
     gene            15643..16200
                     /locus_tag="IE289_RS32305"
                     /old_locus_tag="GCM10010317_066650"
     CDS             15643..16200
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF036586.5"
                     /locus_tag="IE289_RS32305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_066650"
                     /product="SdpA family antimicrobial peptide system protein"
                     /protein_id="WP_099920826.1"
                     /transl_table=11
                     /translation="MSTPVARRQLYIFATTLAVMVAYLLVALFYTLPSNALSSRHSKGA
                     RQYFNDVTPQVWAFFTKDPEGVQIGTYAFDGKHSKNLLKTPQGSPSNLFGLDRSQRAQG
                     PEIAYINTSVTQWNACAGNLEICLHEAAARPAEKVKNRNPVRTVCGDSFITQERVVPWS
                     YRNLVTYDRRITRIAHLDVSCS"
     gene            16191..17180
                     /locus_tag="IE289_RS32310"
                     /old_locus_tag="GCM10010317_066660"
     CDS             16191..17180
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04033.1"
                     /locus_tag="IE289_RS32310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_066660"
                     /product="sporulation-delaying protein SdpB family protein"
                     /protein_id="WP_190172274.1"
                     /transl_table=11
                     /translation="MLITARSAVSALIEEQAARLQLRLSTFDFRSRWFGVGRSLICFAE
                     LTVVLITPSKALLTPVLTVSDGARCEGVRAASAYCLVGGTSHAEYARWILVAVLLVAAV
                     GYRPRWTAIPQLWAIYSIAVSITVPDGGESVSMIMSLLMLPIVLTDNRRWQWSPPVKPL
                     RPSGHAVAYAAFWAVRLQLAYIYLDTAISKFGVADWANGTAEYYFLRDNMFGVAKPWGG
                     PLLALSKYPLIVVGMTWGALVVELLIAVCILGSDRWRKVGLVLDVLLHGSIVLLMGLWS
                     FALVMIGCSVVASMPLSRTSPTATPDEQLPLEIGTNDTSVDRSPAVLG"
     gene            17185..18108
                     /locus_tag="IE289_RS32315"
                     /old_locus_tag="GCM10010317_066670"
     CDS             17185..18108
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.5"
                     /locus_tag="IE289_RS32315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_066670"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_190172275.1"
                     /transl_table=11
                     /translation="MAKLEVLSVSAGYRGRPVLRDVNLEYGAGIHVLLGPNGAGKTTAF
                     RVLAGILAPFEGTVLVDGADPHAHTEAKSLIALATHRSALAPRLSVVDNLRYWARVLGL
                     PPGQSEQRIAEVLDLLGLADLADRRIGSLSRGQNQRAGLAKAFLGRPPILLLDEPMSGL
                     DPTTTAQLTGYLRGLANEGHTVVVSTHALADANRFADDVTVLQEGRIVGRGEPAALRTA
                     LLGSAYRLRIRGSGDVPAVLDRLGLRYEEQQGAVVVEVPDEGAVEVLVADLVREGIGVR
                     EVVPARNPLEDVYQQLQTEGASRDAT"
     gene            18095..18931
                     /locus_tag="IE289_RS32320"
                     /old_locus_tag="GCM10010317_066680"
     CDS             18095..18931
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE289_RS32320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010317_066680"
                     /product="hypothetical protein"
                     /protein_id="WP_099920823.1"
                     /transl_table=11
                     /translation="MTRRSVSFDVTRARILASALLWRMRRERLRNFATVFLPFVLTVAS
                     VVALPLVSDDSDMNGAASSARLGLQYGAHADTVAAGLLLVLMPGVIALHGTVGAGLAVR
                     NVVGAEAGVGALEAMLGAPYNPASIAGGLLSYVLVVTTGQWAVMSALGALAVALSSALH
                     HDSLTPGAGYLTLALVLPLLATWAGAALALLLNLLFPRLSQPGAGALAGNGGGLVSLAA
                     MLPGFGALLAMSIALDPLGPTRLLLYAGGVTVLITTGSLVGIARGFRPESVLSSST"
     gene            18991..19308
                     /locus_tag="IE289_RS32325"
                     /old_locus_tag="GCM10010317_066690"
     CDS             18991..19308
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE289_RS32325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010317_066690"
                     /product="hypothetical protein"
                     /protein_id="WP_099920822.1"
                     /transl_table=11
                     /translation="MFMVMVKVLVDIRPSLVALPFHRAFTRPVVEIDGVEWPARWGTTE
                     VSVEAGAHEMAVFFRYKGQRTARLGVGTEELTVHSDAGTQPRVRARLGPRNGSSFKVES
                     V"
     gene            19330..19548
                     /locus_tag="IE289_RS32330"
                     /old_locus_tag="GCM10010317_066700"
     CDS             19330..19548
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE289_RS32330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010317_066700"
                     /product="hypothetical protein"
                     /protein_id="WP_099920821.1"
                     /transl_table=11
                     /translation="MPQKSIVQCSAGHLYMATWIPFVGIKSLRLTPSTRYARCPVEKHW
                     AVVSRPDPSTLTEEQLTAAQSHDAGWM"
ORIGIN
        1 cgacccccgc gtacacgtcc gtgcccaacc gcccccagcc gggcggcatc ccggcggagg
       61 ccgacgagaa cgtggtggcg gtcttcagcg ccgccgtgcg caagggccgc tggcgcgccg
      121 ggcgccgcat ccacgcgtac gccgtcttcg gctccgtcga catcgacctc agcgaggcga
      181 tcttcgagta ccaacaggtc gtgatcaagg cgatatcggt cttcggcaac gtcgagatca
      241 aggtcccgga gaacgtctcg ctgcgcggca gcggcggcgg agtcctcggc aacttcgaga
      301 cgcacaccac ggacgcgggc gaccccgacg cccccgtggt ctacgtcgaa ggcttcgcgg
      361 tgctggggaa catcgaggcg cggcccaagc gcggcaagct cgtcgccgac atcctcgacc
      421 gcacgatgga ccgcgtggac aggactttgc gcaagcacct cgaccgttga cgcctgtgaa
      481 cgcgacggcg cgcggggcgc attggtccac tcacccgcgc cccgttttga acgaccggct
      541 ccgctctcgg gaactcagtg cataggcgcg cgcacagcgg gtagggcttg ctgcatcgcc
      601 tcttggaggg cgctgtggga cttcccgcgg tgcccggcac gcccgcgaag ccgtcgtcag
      661 gagtagaccg tgctgcaacc gccgcatcag tccctgcagg tagctgccgt tccggcgcag
      721 cgggcgccag tgcgggacag ggatcaggaa gccccatggc acacggaggc ggtgtgccgc
      781 agggacgagg ccggcctgtt cttcgcgccc tccaaggagc ccacggccgc ccggttgtcc
      841 cgcgaggagg cggcgaagcg cgtctgcgcc cgctgtcccg tgatggtcga gtgccgcgaa
      901 cacgcgctgc tgcaacccga gccgtacgga gtgtggggcg gcctcaccgc cgccgagcgc
      961 cgcgtggtgc tcgcccggcg ccgccgccgc gacctggaac tcaagaaggc cgcccgcggc
     1021 acgatagccg cagccggctg accgcacgta cgccaaaggg gccgccctcc gcacagggcc
     1081 ggcccctttg ccgtacgtac ttcttcacgc gccccgaagg ggcgcgggga actgcgcgac
     1141 cagccacgac gcacccgcag tgacctacga actcgcagtt ccccggcact cccggcggag
     1201 cgcccccgcg gagctacttg gcgcggtcga agtcgatcgc gctgtacgcc cgcaacttgc
     1261 tcagccgatg ctccgaccga atctggcgca ccgtacccga cttggaccgc atcacgatcg
     1321 actcggtggt cgcggtctcc gcccggtacc gcaccccgcg cagcagctcc ccgtccgtga
     1381 tcccggtggc gacgaagaac acgttctcgc cggagaccag gtcgtcggtg agcagcacac
     1441 ggtcgaggtc gtgcccggcg tccaccgcgc gctgtcgctc ctcgtcgtcc ttgggccaca
     1501 gcttgccctg gatggtgccg cccaggcact tcacggcgca ggcggagatg atgccctcgg
     1561 gcgtaccgcc gatgccgagg agcaggtcga tgcccgtgcc ctcgcgcagc gcgaggatcg
     1621 agcccgcgac gtcgccgtcg gagatcagct tgatccgggc gccggtctcc cggatctcct
     1681 tgatgatccc ctcgtggcgc ggccggtcga ggatcacgac ggtgacgtcc tcgggcgagg
     1741 acttcttggc cttcgcgacc cggcggatgt tcaccgagac gggcgcgttg atgtcgacga
     1801 agtcggcggc ctccggcccg gtgaccagct tgtccatgta gaagaccgcg gacgggtcga
     1861 acatggtgcc gcggtcggcg gcggccagca ccgcgatcgc gttgctcatg cccttggcgg
     1921 tcagcgtggt gccgtcgatc gggtcgacgg cgatgtcgca ctcggggccg gtcccgtcgc
     1981 ccacgcgctc cccgttgaag agcatcgggg cctcgtcctt ctcgccttca ccgatgacga
     2041 cgacgccgtt catcgagacg gtggagacga gggtccgcat ggcccggacg gcggcgccgt
     2101 cggcgccatt cttgtcgccg cggccgaccc agcggcccgc ggccatcgcg gcggcctcgg
     2161 tgacccggac gagttccagg gcgagatttc ggtcgggggc ctcggaaggc acctcgagtt
     2221 cggacggcag atgatgctcg gtcatcggag cgcacctttc tgatacgacg acggccggat
     2281 gagggtgtgc cccgactcta tcgtcaggct gacaaaatga gcagggggcc ccacggatga
     2341 gcaggccagg gcacctgcga cgataggggc gtggcaggta cgaaaggcaa gcagagcgtc
     2401 cgggacatgc tcctctccct gggtctgatc gggctcatgg cgggcgtgat ctacatcttc
     2461 atcccgcacg acgactccgc gcctcctctc aagcgcgtcg actaccgcgt cgagctgctc
     2521 acggcgcgcc gcgcggcgtc gtatcccgtg gcggcacccg tgggtctgcc gacggcgtgg
     2581 aaggcgacct cggtgcggta cgacggcacc gagttcgatg cctggcacct gggcttccac
     2641 gaccccgacg gtcagtacgt ggcgatcgag cagtcgactc agcccgcggc cgtcttcatc
     2701 gactcggcca gccagggcgc caaggagacg aaggccaccc agcggatcgg tgacgcgacg
     2761 tggcagcggt acgagggcga caagtacgac gccctcgtgc tcagggccaa gggggcgacc
     2821 accgtggtga ccgggacggc gtcgttcggg cagctgacga agatggcgga ggcgctgaag
     2881 acgtcatgac gtcatgatgc gttcgcgtaa tacgtccgtg tacgcgtatg agaagggccc
     2941 ccggcgccat tgccgggggc ccttctcgtc tcatgcgcgt acgcgccggg cgcacgcggg
     3001 ggctcagacg gtcgtgatga cctggtcgaa ctccaggcgc ggggagcgcg ggaaccaggc
     3061 gtcctcgccc ggcttgccga tgttgacgac catcagcggg gtgtggtcgt cgtccaggaa
     3121 ctccttctgg acgcccgcga agtcgagacc ggtcatcggg ccggcggcga ggccggcggc
     3181 gcggacgccg atgatgaagt acgcggcctg cagggcggcg ttcagcgagg cggcaccctc
     3241 acgggccggg cgctcggcga agaagacgtc cttggcctgc gggaagtgcg ggaacagggc
     3301 ggggagctcc tcgtggaact cgttgtccgc ggagaggatc gcgaccagcg gggcggtggc
     3361 ggtcttgggc tggttgccct cggccatgtg ctgcaccagg cgctcgcggg cctcggcgga
     3421 gcggaccagg gtgatgcgca gcggcgactg gttgaaggcg gtcgggccgt acttgaccag
     3481 gtcgtagatc gcctgcacct gctcgtcggt gaccggctcg tcggtgaacg tgttggcggt
     3541 acgggcctcg cggaacagga ggtcctgggc ggcggggtca agaacgagag acatcagaaa
     3601 ccttctcggg atgtgcggtg gatccggggg gatcggttgg cgatgtcgac agtacgggga
     3661 tgaggtttaa ggttcaacca aaaacgacgt gaggtgatcc gcttcacagg gagtgagggg
     3721 gagtgaggtc gcttccgggc gccagggttc cgggggaacg acgaggccgc cgtcaccgag
     3781 cgggacggcg gccgggtgtc actggggatg tcgccgggtg ctaccggctg cggaagggag
     3841 cgaacgtcat gacgtcaccc ggagtcgcgg cctccgtctc cgtgcccgtc tccgtcctcg
     3901 ctctccgact cctcctcggc cagcgccgcg tccaggcggg cccgtgcgcc ctccagccag
     3961 cggcggcaga ccttcgccag ctcctcgccc cgctcccaga gcgccagtga ctcctcgagc
     4021 gtcgtgccgc ccgcctccag tcggcgtacg acctcgatca gctcgtcccg cgcctgctcg
     4081 tacccgagcg cctcgtccac cttgctggtc atgcgcccac cctatgcatc gactcgtacc
     4141 gtgaattcac cctcggcgac ccgcgcccgc agcgcctcgc ccgccgccac ctcgtccgga
     4201 tcccggacca catgaccgtc ggtcttctgg agcaccgcat acccccgttg gagggtcgcg
     4261 gcgggggaga gggccaccac acgcgcgtgg gtgtgcgtca gctccgagtc ggcgcggtcg
     4321 agcagatgcc cgagcgtgcg ccgcccgcgg tccagcagcg cggtgacctg gtcggcgcgc
     4381 tcgtcgacca tccggtgcgg atcctctatc gagggccggg ccagcgcgtg cgcgagcccg
     4441 cgctcctccc ggtcgatgaa ggcctggacg ctccgccgcg cccggtcccg cagggatcgc
     4501 acccgctcgt actcctcccc gacgtccggc acgaccttct tggccgcgtc cgtcggcgtg
     4561 gacgcgcgca ggtcggccac gaagtccagc aacgggttgt cgggctcgtg cccgatggcc
     4621 gacacgaccg gcgtacgaca ggccgcgacc gcccgtacga gctgctcgtc cgagaacggc
     4681 agcaggtcct ccacgctgcc gccgccgcgc gccacgatga tcacgtcgac ggtgtcgagc
     4741 gcgtccagct ccttcacggc ctgcacgacc tgcggcaccg cgtgcacccc ctgtacgggg
     4801 acgttgcgca cctcgaagcg gacggccggc cagcggtgcc gcgcgttctc cagcacgtcc
     4861 cgctcggccg cggacgcccg cccgcacacc agcccgatga gctgcggcag gaacggcagg
     4921 gcctttttgc gatcggcagc gaacagcccc tcgctcgcca gggacttctt caactgctcg
     4981 agtcgcgcga ggagttcccc cacgccgacc ggtttgatct cggtggcccg cagcgacagc
     5041 tgcccgcgcg gcgcgtacca ctcaggcttc gccaggacga cgacgcgggc accctcgctc
     5101 accacgtccg ccaccgcctc gaacacctgc cggtagcagg tgacgctcac cgagatgtcg
     5161 tacgacgggt cgcgcagggt caggaagacg acgcccgcgc cggggcgccg cgacaactgg
     5221 gtgatctgtc cctcgaccca caccgcgccg agccggtcga tccaccctcc gatgagccgc
     5281 gacacctcgc cgacgggcag tggggcgtcc gcggacgtgt tgagagccat gcgcccgaga
     5341 gtaacggccc ccactgacac gaggcccgca cgcgttcttg gcgcggagcg ccgtggtttc
     5401 ccggcacgga gcgccgaagc agccccccgc ccccgctacc cgtcggacgc ctccacgatc
     5461 acggcaacgg tgaccgcggc cccgatcacg cggaccagga catgccgcca ccacaccacg
     5521 ggcccgcccc gacgccgtac gaaccccccc caccacactc gcgtgcggca gcgtgaacgc
     5581 ggtcagcgcg ccgatgtcga ccaccgacac cagacggtcg agcccgtcgt cgcgccgcgc
     5641 cgcccacacc gccgcgacca gcgtgatgaa cgcggcgcac agcggcgcgg cccgcggcac
     5701 cccggagtcg gtcttcgaca gcgcccgcgg cagccgccgg tcgcgggcca ccgcgaacac
     5761 cagccgcccc gccgcggcct gcccggcgag cgcggcgaag gcggcgccga tcgccttgct
     5821 cgcggccacc aggttgtgcc caccccgtcc ggctccccct cggtctcccc aaggaggcga
     5881 tctttgacgc gtcgggcgcg gccttacgat gggtgccatg actgcttcgc ctggccgccg
     5941 tgtcctgctc gccgcccccc gtggctactg cgcgggcgtg gaccgcgccg tgatcgccgt
     6001 cgagaaggcc ctcgagcagt acggggcccc gatctatgtc cgccacgaga tcgtccacaa
     6061 caagtacgtc gtacagaccc tggagaagaa gggcgcgatc ttcgtcgagc agacggccga
     6121 ggtccccgag gggtccatcg tcatgttctc ggcgcacggc gtcgccccgg tcgtccacga
     6181 cgaggccgcg gccggcaagc tcgccaccat cgacgcgacc tgcccgctgg tcaccaaggt
     6241 ccacaaggaa gccgtccggt tcgcgaacga ggacttcgac atcctgctga tcggccacga
     6301 gggccacgag gaggtcatcg gcacctccgg tgaggcgccc gaccacatca ccctcgtgga
     6361 cggtcccgag gacgtcgcca aggtcgaggt ccgcgacccg tccaaggtcg tctggctctc
     6421 ccagaccacg ctgtcggtcg acgagacgat ggagacggtc gacgcgctga aggagaagtt
     6481 cccgcagctc atctccccgc ccagcgacga catctgctac gccacgcaga accgccagct
     6541 ggccgtgaag cggatggggg aggaagcgga cctggtcatc gtggtcggct cgcgcaactc
     6601 ctccaactca gtgcgtctcg tcgaggtcgc caagctcgcg ggggcgcggg cggcgtacct
     6661 cgtggacttc gccgacgaga tcgaggaggg ctggctggag ggtgtgacga cggtcggtgt
     6721 cacctcgggc gcctccgtcc cggaggtcct ggtcgagcag gtcctggagt ggctctccgc
     6781 ccgtgacttc gaggacgtcg agatcgtcaa ggcggccgag gagtccatca ccttctcgct
     6841 gcccaaggag ctgcgccgcg atctgcgcgc ggaggcggcg gcgctggtgg agcagcgcac
     6901 ggcggcgggt tctgccgccc cctccgagaa gtgactgtct gtcgtacgac gtagcgtagg
     6961 gccatgcaga tcttcggcgt ggacatcggc ggatccggga tcaagggtgc ccctgtggac
     7021 ctggaccgcg gcgaactgac ggaggagcgc tacaaagtgc tcactcccca tccggcgacc
     7081 ccggacgcgg tggccgacgg cgtgaaggag gtcgtcggtc acttcggctg gacgggaccc
     7141 gtcggcatca ccttccccgg ggtggtcacc ggcggcgcca ccattcgtac ggctgccaat
     7201 gtcgacaagg cgtggatcga caccgacgcg cgtgccctgc tgggtgagcg gctgggcggc
     7261 ctcccggtga cggtgctgaa cgacgcggac gcggcgggtg tcgccgagat gcagttcggc
     7321 gccggacgcg accgtcgggg cacggtcctc ctgctcacct tcggtacggg catcggcagc
     7381 gcgctcttcg ccgacggcga gctggttttg aacacggagc tgggacacct cgagctgaac
     7441 ggccacgacg cggagaagcg tgcctccacc aaggccaagg aggaccacga gctgacctgg
     7501 gagcaatggg cccaccgggt gcagaagtac ctcgcccatg tggaaatgct cttctcgccc
     7561 gagctcttca tcatcggcgg cggcgtcagc cgcaaggccg acaagttcct gccgctgatc
     7621 gagggcatca aggcggagat cgtcccggcg cagctgcaga acaacgcggg gatcgtgggg
     7681 gcggcgatgc gggcagcgaa gtccgcgtag gccctccggg gcgcgcgggg cggggccggg
     7741 agccggcgcc ggtgtggccg cgcccgtcga gttcgtcggc cccgtcacgc ccgtcgcgcc
     7801 cgttgtgtcc gtcgccccga tgtgtccgtc gggcccgtcg tatccgtcgc gcccctcgtg
     7861 tccgtcaggt cggacggcgg cgcggccgga tctcctggcg gggctcccgg gccgccctgc
     7921 gctgggcggc cctgcgggtc atcaggcgga ccttccgtac ggtggtgatg acccccgcga
     7981 tcagcgtccc cccgtacagc catcccgcct gggtcgccag cgcggtgacc agccccatca
     8041 gttcgccccc gatcccgccg cccccgtcgg cgacgggcag cagcccgaac gcgaaggcga
     8101 tgggcacgac gacgggcgcg gtgacgatgt ctccccgtcg cacccacagc gcggtcagcg
     8161 cgcacaccgg caggaacagc accccgtaga ccaccagcga cgccccgaag agcagctggt
     8221 cgagacaggc gagcgcgaac atcgtcgccc cgcagaacag tccgccgccg agcccggtga
     8281 gccgggggtt cggcatccgc cgtcgcgccg gagcgggcgc gggcgcgggt cgccgcgcgg
     8341 gaggcgcact cctgcgtaca cggtcggcgg cggcgcgccc ggtctgggcg ggaagaggtg
     8401 cgccgcgtcg cggtctgtac tgagggggac gcgtcctgtg ttgctccact ggaccaactt
     8461 aggtcggttt atgtgcggaa tagcccctca gacacgccga tgggccgacc ttggccatgc
     8521 gttcgaagcg tcgccggtaa gggacctcgc accccgtaga ctggtggatc ggcccgcgca
     8581 ccttcgcgga cctgtcgccc accctcacgt acgggaagtc gcaacgtgtc gctcacgatc
     8641 ggaatcgtcg gtctgcccaa tgtcggcaag tcgaccctgt tcaacgccct gaccaagaac
     8701 gacgtgctcg cggccaacta cccgttcgcc acgatcgagc ccaatgtggg cgtggtcggt
     8761 gtccccgacg cccggctgac caagctggcc gagatcttcg gctcgcagcg cgtgcttccg
     8821 gcgacggtcg acttcgtcga catcgcgggc atcgtgaagg gcgcctcgga gggcgagggc
     8881 ctgggcaaca agttcctcgc gaacatccgt gagtcggacg cgatctgcca ggtcatccgt
     8941 gccttcaagg acgagaacgt cgtgcacgtc gacggcaagg tctcgcccaa ggacgacatc
     9001 gagacgatca acaccgagct gatcctcgcg gacctccaga ccatcgagaa ggtcctgccg
     9061 cgcctccaga aggagtcgcg catcaagaag gacatcgcgc ccaaggtcgc ggcggtcgag
     9121 gcggcgaagg agatcctgga gaagggcgac acgctcttct cgcagggcat cgtccagggc
     9181 tccggcaacg aggagctcct gcacgacctc cacctcctga ccaccaagcc gttcctctac
     9241 gtcttcaacg tggacgagga cgagctggtc gacgaggact tcaaggccga gcagcgcacc
     9301 ctggtcgccc ccgccgaggc gatcttcctc aacgccaagc tggagcagga cctcgccgag
     9361 ctcgacgagg aggacgcgat ggaactcctg gagtcggtcg gcgccgagga gcccggtctc
     9421 gccaccctcg cccgcgtcgg cttcgacacc ctcggcctgc agacctacct cacggccggc
     9481 cccaaggaat cccgcgcctg gaccatcaag aagggcgaca ccgccccgga ggccgccgga
     9541 gtcatccaca ccgacttcca gaagggcttc atcaaggcgg aggtcatctc cttcgaggac
     9601 ctcgtcgaca cgggctcggt cgccgaggcc cgcgccaagg gcaaggcccg catggagggc
     9661 aaggactacg tcatgcagga cggcgacgtg gtggagttcc gcttcaacgt ctgagcaggc
     9721 gaaataacac cacgttggct gcctggcgaa catacaggtc aaatggggtc ggctcttccg
     9781 ggagccgacc cctgctctct ttccgctgat caagaggtca acgacgatca cgaggccatc
     9841 gagatcgtct ccaagcacgg caacgccgtg cttgtcccgg ccgaggacta cgcggcgctg
     9901 cgcgagggct cgtacctgct gcgctctccg gccaacgcgc gccgactgca caaggcgtgg
     9961 cgccgtgtga ggctcgtctt agaggatcag gtcttctgtt tcaacgtctg gcgctcctcg
    10021 cggcccggcg agcattccgc aggatccgca gcgtgcccag cagcggaggg ctcgcggagc
    10081 cgtgcagcag cgccgctccg cgtgccagtg ccgcgtcggc cgtcagcaac tcgatctcga
    10141 cgaatgcgtt cagcagtgct tggccagggg ccgagacctg ggtgggcagc tcacgggctg
    10201 cctccagggc ggcccgggcc gccctgacct cgtgctccac caacaggcgc aggcccggcg
    10261 gttcatgccc cgccgcgagg tccgccaccg tgaccgagaa tcgcgccagc gtctgagccg
    10321 gaatgctcgg tcgcccttcc gtgatgtcct cggcgagatc attgacgaag tccagtcgct
    10381 ggctgccgtc gatgagcgtc cggcacatcg cccggtaccg gccgtcgtcg tcctcaggac
    10441 ccagcagtac ggcaaccagc atgaaggcgg gcagtgagta ggcgtccacg taggcctggt
    10501 agtcggcctc cgagacgaag ccggtgaact ccagctcggc gccggcggtg gacagatact
    10561 cctccaccac cccccgaagc cgcggatacg cggcgacggt gtgcagcaac gtgcgggtca
    10621 gcgggtcgtc ggccaccccc gtttccagcg ccttgcgcac ccgccgctcc caggacgccc
    10681 aagccgcgat ccgctgcggc ttggggccgg tgtccagcac gttgtccccg tggtgcatca
    10741 cggccgtcgc ggccaccaca tgcggcagca tcgacggcgg cagcagcaaa cgggccgcca
    10801 ggtaggaact acggcgaaac cgagccacca gccgacgccc gtcgtcgtag tcgttccgca
    10861 gctccggttc ccggacccca gccgcggtca ggctccgctt ccacgtgctc accttcgtca
    10921 ccgtcccggg catagcccgg cctgtgcctg gacatgtgtg cgtcggccgg cggcagcaat
    10981 ggtgttgccg gcgatgagga ccgcggcgtc ctccacatgc tcgtcatcgg gtccgagcag
    11041 catgtgtcct gccgtgatga gaagttcagc cacgccgact cctgtggtgt tccttgtgtt
    11101 ggtcttgttg gtcttgctgg tcctgctggg cggggtgcga ggtgcgacgg agcagcgcgt
    11161 ccgacagcat gacgagctga cgtacgtccg cgtccaggcc ctgtgcctgc ggtactgcca
    11221 cggcgaccgc gccgtacggc gcttccccgc cttccgcctg ggcttcgagg gcggcacaca
    11281 actggtccgc aaggagatcg gccgaggact cggagaggtc cgtgaccgtc tcctcggcct
    11341 gcccgagata ggggctgatg cgcaccagcc cgtcgcggca ctcgatggcg cggcggtagt
    11401 agtggcggtc gactgcgcgc ggccggcgta gaaggcccca tggcctggcg cggttctggt
    11461 ggagagcgtg ctgcgggtat gcctcgtgca gcaggctcca cagcggatgc aggcggtggt
    11521 acatgctgcg tcgttgccgg cgcaggcgca tgaccgagag acgggtgagg gcggccgggt
    11581 agccggctcc gatgaggaac aaggggatcg ccacggcgat gatgtggccg gagaacttgg
    11641 tgacggccgg ggcgacagcc cctccgtgcc agcggatcac ggtcagtgcc gctcggatcg
    11701 cgctcgccgc ggctatgccc gagagggcgg acgccatcag ccacaggccg acggacaggg
    11761 ggcgtggtga cgctcgcgcg taacgacagg tccagagcag ggccgcggtc agggcgtaga
    11821 ccagatagag atcggccagg agatagaagg tcgccagggc ggacacccgc atgtcgacgc
    11881 tgtcatagct gccgcccgtg tcgtgtccgg cggcggcgat cgtggccagt gaggtcccca
    11941 gaagagtgag tcccaggggg agtgtttccc gacgggcgcg tatgcgtcct ctctgcgggt
    12001 ccgttgcgga gtacaggtag aagcacatca gccagaagac catggcgaac gcgaaagcgt
    12061 tctgcaccag ccgcggcgct ccggacccgc cgacggagcg gattgccttc gcggcgggcg
    12121 gcaacgcgag tccgaatgag gcggccgcac tcgccagaca cagggtcacg gcacgcaacg
    12181 gagcgtcgtg tggggacgtg acgaactggc gtatcttcca gccgagggtc aggacgaaca
    12241 ccgtaccgac gacgagtgcc agcgcgatca ttgccagccc tgccgatcgc cgagtgcgga
    12301 ctggacgcgg tcgaccgacg ggtccacgga cgaggacgag tcgacgtagt ccaacacgga
    12361 ggcccattcg aggatgatgg tggcgaccag ctcggcctcg cgttcgtgct cttcgtcata
    12421 cgaggtgcgc aggagtgtct tcttgatgac gtcgacagag atgtcgggca tcagctgctg
    12481 ccagatctcg tcgccggaca ccgtgctgcg gtggtcggcc atgatgtgcc cgacctcgtg
    12541 caggatgatg tggtcctggt ggaccttgct ggtctcgcgc tgatagagga tgtagtccgc
    12601 cgagcgcgtc gagatccaga cgccgaacgg gccggggacg ggcagcggat agggcatgag
    12661 acggatgggc cgtccgcggc gctctccgag gcgtcggcac agcacagcca cccgtaacgg
    12721 cggctcaatg ccgagggatt gaagctcccg tttgcagcgc cgacgcagct tgcgctcgtt
    12781 caagaccgtc ctctcgcatg tctgaccccc gcgccgccgg tcggacagca cgggctcagg
    12841 tgggggtgac cagagggaat gtccgggcag ttcacggttc cgcgtggttc acggccgtcg
    12901 cgtggtgccc gtcgtcagca tccgggtgag cggctgcttc tgtatctgtt tctacgtctt
    12961 tgtcgtctac gtcacgtacg cgactggtgt cgtccaggtc attgcgtgtc ctgctgcttc
    13021 gcctcggcct gttcgaggcg gtagacgacg tcgaggaggt ccatgacctg tttgcggcgc
    13081 tcgccggaca gatggcccgc ccgcatcgcc atcagcttga cgtcgctctc tggcgaggaa
    13141 tcggccaggc gtgcctgggt ctcggcaagc agcttcagct gctcggcgac gcggttgttc
    13201 gtttccgtgt cgaggaagta ggcggccggc acaccgaaga aaccggccag cgcttccagg
    13261 tgcttgagcg tcggattgtt cttgacgcct ttgcgcagct gccagatgta gctttgcgaa
    13321 atggtgacgc ccgtacccct gatggcggcc gcgacctgct cgttgctgta ctcgtggcct
    13381 acgtcgggcc gtacgttcgc aaagagctcg ttgagcttgt cggcaagact gcggttcgcc
    13441 ccctcggcca tggtgtctcc ccgcgctctt ccactggcat gaatgtgaac agagtgtagc
    13501 gagttcatat cagttgaacc aggggaacct gtggtctagg gtcttgacac acgacgatct
    13561 caactgtggt gaaagcccgg cccgtcgaac tctgttcctg agtcgacgga cgaccaccgg
    13621 gcggaaccat cggttggctc cactcagggg gagagggtgc tgtggtgtcg gcaacgtcgg
    13681 tgacggggga gatcgctgag ggagcgatcg tcccggcaac accggaagaa atcgggggag
    13741 ttctcgaccg ggcagtggag cgggtgccga tccgcctgct gtcaggggtg agttcgcccc
    13801 gcacgtcggg cgcggacgac cggcacgtac gggcgctcgc cgaactggac gtacccctgc
    13861 cgcccgtcgt cgtgcaccgc ccgacgatgc gggtgctcga cggggtccac cggatcaggg
    13921 cggcggaact gcggggggag agcgacgtcg aggtccggta cttcgacggt ggcgaggagg
    13981 aggccttcct gctcgctgtc cagctcaact cggcacaagg caaaccgctg tcgttcgacg
    14041 acaggaccgc ggccgcgctg cgcatcgttg cctcgcactc gcactggtcg gaccggcgca
    14101 tcgcctcggt gacctgcctg tcggccaaga ccgtcgcggt tctccggggg tgttcgaccg
    14161 aggacgggcc gcagtcgaac aaacgggtgg gcctcgacgg ccgcgcacga ccactgcatc
    14221 cggccgaagg gcgcttgctc gcgggcgagt tactggcgaa ggatccgcac ctctcgctgc
    14281 gcgagctcgc ccggcgtgcg gggacgtccg tggcgacggc gagcgatgta cgtcaacggt
    14341 tccttcaggg acgggagttg ctgccgacga ggctgcgcgg cggtggaccg cccgaggacg
    14401 gcgggccccg gtcccgtcgt cacgatgacg gcggcggttc gagcggcacg ggcgtccccg
    14461 gcggcttcag cggcgggggc cgccccggga gccccgccct gctcgaaagt ctgcgccgcg
    14521 acccctccgt ccggcacacc gaatcggggc gcaggttcct tcagctgctc agtattcacc
    14581 cgacgggccc ttctgaatgg cagaagctcg tccgtgacgt cccggcccat cgcgccgatg
    14641 tcgtcgcgcg tatcgcacgg gattacgcgg aggcgtggct tcatgtcgcg cgcacgctgg
    14701 aaagcaattc ctgaccgtca tgcgataact ccggtgtgcc gacctctggt tggacattcc
    14761 ttgtcgtcga aaagatgccc gaatagcgtt ctgaatcgct tgaggaatcc tcaacgcccg
    14821 taagtgcacg ggattctcgg aaaactcttc aacaaacagg ggaagttcca tcatgagatt
    14881 gaagaagccg ctgatcggcg ccgtactcac cgccaccatg gtggccggcg tcgccggcac
    14941 cgcgtcggcg cacacccagg cgccccacac caccccggcc gccgcggccg aggcggcgca
    15001 gggctactcg gacagcgacg tggtcgcctt cctggtcttc ggccagggca aggccgcgga
    15061 ggaccacccg gagttggccc agcagatccg cagccgtcgc tccgacgcct cggtgacgcc
    15121 cgcacagctg tcgtacctga tggccaagct gcaccaggcc gacccggcct tccacaccaa
    15181 ggtgacgaag gccgtccagg ccaaggaccc gttcgtggtg cagcagggca tggtggcgct
    15241 gaacgacgac ctcaaggcgg ccatcgcctc ggaccgcaag gccaagaccc tcaacagcgc
    15301 cgacatcgcg cgccccaacg gctgggtgtg gaccaagtcc aacatcgtga ccgtggcgaa
    15361 cgtcgcggcc ggcatcaaca tcgccgcggg caccaacgtc gccgcgggcg cagaggtcgt
    15421 cgtggtcgtc gtgatagccc cggccgcggc cagctacggc ttcgacctga agcagtcgga
    15481 ccagctcgac gagaacgact tcgtcgcggc ggtcacctcc gctctctgat ttctccgcgg
    15541 gggtggcctg ccgcgaccgc ggcgcggcag gccacccccg cacaggggca tcagtacggc
    15601 cggaagtgtt ccgtccattc cagggggaaa ggaaaaccgc gcatgtcgac gcctgtcgca
    15661 aggcggcagc tctacatctt cgcgaccacg ctggcggtca tggtcgccta ccttctcgtc
    15721 gcgctcttct acacgctgcc gagcaacgcg ctcagcagcc ggcattccaa aggcgcacgc
    15781 cagtacttca acgatgtcac cccgcaggtc tgggccttct tcacgaagga ccccgagggc
    15841 gtccagatcg gcacgtacgc cttcgacgga aagcactcca agaatctcct gaagaccccg
    15901 cagggcagcc cgtcgaacct cttcggactc gaccgcagcc agcgtgccca gggccccgag
    15961 atcgcgtaca tcaatacctc ggtgacccaa tggaacgcgt gcgcgggcaa tttggagatc
    16021 tgcctgcacg aagcggccgc acgccccgcc gagaaggtca agaaccgcaa ccccgtgagg
    16081 accgtatgcg gggactcctt catcactcag gaacgcgtcg tgccctggtc gtaccggaac
    16141 ctggtgacgt acgaccggcg catcaccaga atcgcccacc tggatgtctc atgctcataa
    16201 ccgcccgttc ggccgtttcc gcattgatcg aagagcaggc cgcccggctc caactccggc
    16261 tttccacctt cgacttccgc tcgcgctggt tcggcgtggg acgctcactg atctgcttcg
    16321 ccgagctgac ggtggtactc atcactccgt cgaaggcgct gctcaccccg gtcctgaccg
    16381 tcagcgacgg tgcgcgctgc gagggagtgc gtgccgcgtc cgcgtactgc ctggtgggag
    16441 gcacctccca cgcggagtat gcccgctgga tcctggtcgc cgtgctcctg gtggctgccg
    16501 ttggataccg gccgcgctgg acggcgatcc cgcagctgtg ggccatctac tcgatcgcgg
    16561 tgagcatcac ggtgccggac ggcggcgaat ccgtgagcat gatcatgtcc ctcctcatgc
    16621 tgccgatcgt cctgacggac aaccggaggt ggcagtggag cccgccggtg aaaccgctgc
    16681 gtccgtccgg gcacgctgtc gcctacgccg ccttctgggc ggtcagactc cagctcgcgt
    16741 acatctatct cgacaccgcc atcagcaagt tcggagtcgc cgactgggcc aacggcacgg
    16801 cggagtacta cttcctgcgg gacaacatgt tcggcgtcgc caagccctgg ggcgggccgc
    16861 tgctcgcgct ctccaagtac ccgctgatcg tggtcggcat gacctggggc gcgctcgtcg
    16921 tggaactcct catcgctgtc tgcatcctgg gctccgaccg ctggcgcaag gtgggcctgg
    16981 tactggacgt actgctgcac ggctcgatcg tcctgctgat gggcctgtgg agcttcgccc
    17041 tcgtcatgat cggctgctcg gtcgtcgcgt cgatgccgct gtcgcgtacg tcgccgactg
    17101 cgacgcccga cgaacaactt ccccttgaaa taggcaccaa tgacacctca gttgaccgct
    17161 caccggcagt gctaggttga atccgtggcc aagctggaag tcctgagtgt ttctgcgggt
    17221 taccgcgggc ggccggttct ccgggatgtc aatctcgaat acggcgcggg aattcacgta
    17281 ctgctcggcc cgaacggcgc cggcaagaca acggcattcc gcgtgctcgc cgggatcctc
    17341 gcgcccttcg agggcaccgt cctcgtggac ggcgccgacc cgcatgcgca cacggaggcc
    17401 aagtccctga tcgccctggc cacgcaccga tcggcgctcg caccgcggct gagcgtcgtg
    17461 gacaacctgc ggtactgggc acgcgtcctc ggcctgccgc cggggcagtc ggagcagcgg
    17521 atcgcggagg tcctggacct gctcggtctg gccgacctcg cggaccgccg catcggcagc
    17581 ctcagccgcg gccagaacca gcgagcgggg ctggcgaagg cgtttctcgg gcgccccccg
    17641 atcctgctcc tggacgagcc gatgtcgggc ctcgacccga cgacgacggc ccaactcacc
    17701 gggtatctgc gagggttggc gaacgaaggg cacacggtgg tcgtctccac gcacgccctg
    17761 gccgatgcga accgcttcgc cgacgacgtg acggtgttgc aggaggggcg cattgtgggc
    17821 cgaggcgaac cggccgccct gcgcaccgcc ctgctgggca gcgcctaccg gctgcgcatc
    17881 cggggctccg gcgacgtgcc ggcggtcctg gaccggctgg gcctgcgata cgaggagcag
    17941 cagggtgccg tagtcgtgga ggtgcccgat gagggagcgg tggaggtgct ggtcgccgac
    18001 ctggtgaggg agggcatcgg cgtacgagaa gtggtccccg cccggaaccc gctggaggac
    18061 gtctaccagc aactgcagac ggaaggcgca tcccgtgacg cgacgtagcg tctccttcga
    18121 cgtgacccgg gccaggatcc tggcgtccgc gctgctgtgg cggatgagac gggagcggct
    18181 gcggaacttc gccacggtgt tcctgccgtt cgtgctgacg gtcgcctccg tggtcgccct
    18241 gccccttgtg tccgacgact cggacatgaa cggcgcggcc agcagcgccc gactcggcct
    18301 gcagtacggg gcacacgcgg acacggtcgc ggccgggctg ctgctcgtcc tgatgcccgg
    18361 cgtcatcgcc ttgcacggca cggtcggcgc gggcctcgcg gtgcgcaacg tggtcggcgc
    18421 ggaggccggg gtcggcgcgc tcgaggcgat gctcggcgcc ccgtacaacc ccgcgagcat
    18481 cgcgggcggg ctgctcagct acgtactcgt cgtcacgacc ggccagtggg cggtgatgag
    18541 cgcgctcggc gccctcgctg tcgcgctgtc cagcgccctg caccacgaca gcctcacgcc
    18601 gggcgccggt tatctgacgc ttgcccttgt gctcccactc ctggccacct gggcgggcgc
    18661 cgccctcgcc ctgctgctca acctgctctt cccgcggctg tcccagcccg gcgccggcgc
    18721 cctggccggc aacggcggcg gcctggtcag cctggccgcg atgctgccag gcttcggcgc
    18781 cctgctggcg atgtccatcg ccctggaccc gctgggtccg accaggctgc tgttgtacgc
    18841 gggcggggtg accgtactga tcacgaccgg cagcctggtc ggaatcgcga ggggcttccg
    18901 cccggagtcg gtgctgtcgt catcgacgtg aggcacgtcg agtacgacag ccacccgcca
    18961 caaccaggca actaggcaag gaattcggtg atgttcatgg tgatggtgaa ggtcctcgtc
    19021 gacatccgtc cgtcgctggt ggcgctgccc ttccaccgcg ccttcacacg gccggtggtg
    19081 gagatcgacg gcgtcgagtg gcccgcgagg tggggcacga cggaggtgtc ggtcgaggcg
    19141 ggagctcacg agatggccgt cttcttccgt tacaagggcc agcgcacggc ccgactcggc
    19201 gtagggacgg aggagttgac ggtgcacagc gatgcgggca cacagccgcg ggtgagggca
    19261 cgcctcggcc cgcgcaacgg cagcagcttc aaggtcgagt ccgtctgagg caccagggag
    19321 aagggacaca tgccccagaa gtcgatcgtg cagtgttcgg cgggacacct ctacatggcc
    19381 acatggatac cgttcgtcgg catcaagtcc ctgcgcctca ccccgtccac gcggtacgcc
    19441 cgctgccccg tcgagaagca ctgggcggtg gtcagcaggc cggacccgtc gaccctcacc
    19501 gaggagcaac tcaccgcggc gcagtcgcac gacgcggggt ggatgtagac acgacacgga
    19561 accggggcgg agaccggcgc tgggcgtgcc gaaaaccacg tccgtgccgc ttgggcggcc
    19621 tctttgcgct cccgcgcgcc cggagccggg ccgggctgtc ggtggcgggc agtaatgtcg
    19681 ggccggtggg gaaacgtgag cggagtctgc tcgccgagag cgtcggactg cacgaggccg
    19741 cgcggggtgt gctcaccgat cacgcccgcg cgctcgaagc ggtgcgcgcg gcgctggcac
    19801 cgatccacgc cgaactcgtc ggcaaggagc tggagtccat ccccgtctcc cggctgaagg
    19861 acgtcaccga ggggcggctg cggctcgggg cgctggagac ggccgggttc gcgtcggtgc
    19921 gggcggtgta cgaggcgggg cggtacgagc tgcgccggct gccgggagtg ggcgcgcaga
    19981 ccgccgaccg tgccctcgcg gcggcccggc agctcgcgag ggcggtggag gagaccgttt
    20041 ccgtacggat ggacgtcgac cggcccgagc cccgcacgac cgccctggtg atcgcgctgc
    20101 gcaccctcgt cgaggccggt cccgagctgc gccgggccgt ggacgcggcg acgcggctcg
    20161 acgagcggct cggggcgctg ctgcccgcgg cccggcccgc cggcggacgg ctggggatgg
    20221 tgctcgcggg gcgggagcgg cggcggagcg cgctcgacgc ggtcgccgaa ctgcgcgagc
    20281 tgaccgccga cgccggcgcc cgcgacgtac gcctgctgct cgcgcaggcc tcgaccgacc
    20341 tgctgcggac gcccgcctcc gagatcgagg cgtgggtcga cttcgagttg cgctccgcgg
    20401 agtactacag ccagctcgcc gaggtctgcg agcaccgttc ggacgtggcg gccgccgagg
    20461 gcttcctgcc gtcggaggtc gccgagcggg tgcacgccca gacgctggac gacacccggc
    20521 gccgggtctc gctgcgcggc taccaggact tcggcgcccg gttcgcgctc gcccagcgcc
    20581 gggtcgtcct cggcgacgag atggggctcg gcaagaccgt gcaggccatc gccgtactcg
    20641 cgcatctcgc ggcggacggg cacagtcact tcctggtcgt ctgcccggcg agcgtactga
    20701 tcaactggac gcgcgagatc ggcacgcgca gcacactgcg ggccctgccg gtgcacggcg
    20761 cggagcggct ggacgcctac gaggagtggc gggagcgcgg gggcgtcgcg atcaccacgt
    20821 acgacatgct gcaccggctg cccgccccgg acggcgaggg cacgaagccg gggatggtgg
    20881 tcgtcgacga ggcgcactac gtgaagaatc cg
//
