LOCUS       NZ_BMUQ01000012        35467 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces mirabilis strain JCM 4551 sequence12, whole genome
            shotgun sequence.
ACCESSION   NZ_BMUQ01000012
VERSION     NZ_BMUQ01000012.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces mirabilis
  ORGANISM  Streptomyces mirabilis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 317502)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 117X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650275.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:52:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,392
            CDSs (total)                      :: 10,311
            Genes (coding)                    :: 9,898
            CDSs (with protein)               :: 9,898
            Genes (RNA)                       :: 81
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 414
            CDSs (without protein)            :: 413
            Pseudo Genes (ambiguous residues) :: 0 of 414
            Pseudo Genes (frameshifted)       :: 172 of 414
            Pseudo Genes (incomplete)         :: 329 of 414
            Pseudo Genes (internal stop)      :: 40 of 414
            Pseudo Genes (multiple problems)  :: 115 of 414
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:21:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 18761
            Orig. end                         :: 54228
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMUQ01000012.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..35467
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /product="terpene"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..35467
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="neighbouring"
                     /product="lanthipeptide-class-ii"
                     /product="terpene"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..22895
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22895
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12895](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12895)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(163..2982)
                     /locus_tag="IE289_RS27540"
                     /old_locus_tag="GCM10010317_056750"
     CDS             complement(163..2982)
                     /GO_function="GO:0004555 - alpha,alpha-trehalase activity
                     [Evidence IEA]"
                     /GO_process="GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019058927.1"
                     /locus_tag="IE289_RS27540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_056750"
                     /product="trehalase family glycosidase"
                     /protein_id="WP_229889205.1"
                     /transl_table=11
                     /translation="MVSAALLMAPAPATSAATSSTATGAGKATLDALNYSPTSRTLKPT
                     AIYRTSGSVANPQNVLSGQPTRISGSQSAVTLDFGKEVGGVTTLSFGSTSDSGQRVGLA
                     FSESSLYVGNNSDRSSGRDGEDGALYATASANGTYTVPTAQQRGGFRYLTVFLDTSGWV
                     DLKGVSLNFTAAPGKADPADYANYFSSSDDLLNRIWYAGAYTVQLNTIASNQGRAWPPP
                     SSAWDNGATVGVGDSVLVDGAKRDRTVWPGDMGIAVPTQYAYSNDLVSTRNALTTMYNA
                     QSAEGEIPWSGPPFNLTGSDTYHTWTLLGTSTYYTYSADRAWLDSEWADYKRGMAFITN
                     KIDGNNLLNVTRTQDWARVGQGGENVSANALLYAALKGGATLATVEGDSALAASWNAKA
                     AAIKSAANSLLWDAAKGMYKDNPSSGLYPQDGNSLAVWYGLTDSAAKSKSVIAGLGKNW
                     GIYGPTTPEWGGNVSPFAGGMELNARFTANDDYTALDQIRRTWGHMLTSDIGTKSTFWE
                     GIKADGGLAYGGSFMSLAHGWSTAPTSTLTFDVLGTAPESATGTYRFVPHPGDLTSAEG
                     RITMPQGAVNASWSRDPAAGTYSAHLTSPAGTTGRIGVPKFGGNISVSVNGTVVWSNGT
                     FTPTSGITGASQDDTYVYLTGVAPGGYTVAATGLGNPSPPADPGTGALRPGFTRCAGEG
                     GTCSFSGTRSVAYGAGTYTYKTVTGSTACTNDSFGGDPASNLVKSCYVADAGGPPGYTV
                     CAAEGGTCAVPGYNRDVVYGANGNFAHQVTNGSVACTNAHFGDPIDGVAKSCYVAPAGG
                     PSGGWTKCADQNGTCPAAAGQPVTYGAFGAFTTITATGDTPCTDATFGDPIPGESKACY
                     TATGGPVGYAASCSAEGGTCAFSGQQTVAYGARGRFLYKAFTGGTGCTTAAFGTDPLPG
                     VSKTCYRTT"
     misc_feature    3287..3302
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.92"
                     /tool="antismash"
     gene            3611..5233
                     /locus_tag="IE289_RS27545"
                     /old_locus_tag="GCM10010317_056760"
     CDS             3611..5233
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006140113.1"
                     /locus_tag="IE289_RS27545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_056760"
                     /product="glycoside hydrolase family 76 protein"
                     /protein_id="WP_229889232.1"
                     /transl_table=11
                     /translation="MAWASIDNGVTGDSVWLDRSWDGGATWEGLLGKASVPGTWTGTRT
                     LMYNITDPRNHRRGLVRACGDAAGVGCTNWVYPTVCDTLCDGTDAGKAAGDDQPVPSTT
                     LYGRTIRLHVDQKNSLAWASIDTGGAGDEIWLDRSWDGGSTWPDGSSLGRTSTPSGATG
                     TRTAMYATRDPRGLLYGGAVRACGREASHNEGSCTAWVRPVPTRTRAAADALMSSYDPY
                     NGWWPSSWWNSAATLTALIDSSRATGRHDYDWVIARTFDQNKGTFAAGVRSSDAIEGDF
                     ISRSIDDSGWWAIAWIDAYDYTGDSRYLNEAVTIANYVQQYWDPGTCGGGVWWDRERTY
                     KNAVTNGQYLWLTTALHQRIAGDTVWLQRAKTSAAWYRSSGMINSSGLVNDGLTSACAN
                     NGSTVWSYNQGLAIGGFTELWKTTGDSSLLTTARTLADAAISSPTLTSGGVLTESCDVG
                     SASCDDNQKQFKGIFMRNFADLAKATGSGTYQSYVQKQADTLWARDRSSLNALGERWAG
                     TSPNQTDWRTQAGALEALTAAAG"
     CDS             5413..5577
                     /gene="allorf_024174_024338"
                     /locus_tag="allorf_024174_024338"
                     /protein_id="allorf_024174_024338"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MVPGKPISNARHAPVTQPALHAGSHRAQCGTSRPRCTSRGPHQPW
                     ITAIRRSAS"
     CDS_motif       5413..5481
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MVPGKPISNARHAPVTQPALHAG"
                     /locus_tag="allorf_024174_024338_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       5482..5577
                     /prepeptide="core"
                     /locus_tag="allorf_024174_024338_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.30"
                     /molecular_weight="3317.7"
                     /monoisotopic_mass="3315.7"
                     /core_sequence="SHRAQCGTSRPRCTSRGPHQPWITAIRRSAS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVPGKPISNARHAPVTQPALHAG"
                     /leader_location="[5412:5481](+)"
                     /alternative_weights="3335.7"
                     /alternative_weights="3353.7"
                     /alternative_weights="3371.8"
                     /alternative_weights="3389.8"
                     /alternative_weights="3407.8"
                     /alternative_weights="3425.8"
     gene            5959..6531
                     /locus_tag="IE289_RS27550"
                     /old_locus_tag="GCM10010317_056770"
     CDS             5959..6531
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019547415.1"
                     /locus_tag="IE289_RS27550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_056770"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_190171618.1"
                     /transl_table=11
                     /translation="MRTLISSAFISLDGVMEGPGGEPGYRNSGWTFKDVEFVPEAFDIK
                     AREQQESTAVLMGRTSYEAFSPVWPDMNEFAHYKTMPKYVVSTTLTEDKLVSNWGETSI
                     LRSLDEVAALKETDGGPIIVHGSVALNHSLADAGLIDRYHLLVHPLLLGAGKRLFPATD
                     KDTQKLRLVEHAVYSNGLQMNVLDVVR"
     misc_feature    complement(5983..5996)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.96"
                     /tool="antismash"
     gene            complement(6605..7534)
                     /locus_tag="IE289_RS27555"
                     /old_locus_tag="GCM10010317_056780"
     CDS             complement(6605..7534)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013188.5"
                     /locus_tag="IE289_RS27555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_056780"
                     /product="cation:proton antiporter"
                     /protein_id="WP_268256048.1"
                     /transl_table=11
                     /translation="MPVELLHVSGVLAGVTCGLVTTRFGPRVIGSDARIQAIAFWEVAR
                     YPLNSALFILVGIQLPAAIRALTSVSLAQAAIAACAVSVAVIGTRLLWFYSVPYLVRFL
                     DRRPQQRDRRITAPQRLPLAWAGMRGAISLAAALTVPAVTAEGQVVEQRDAVVFITAVV
                     IVVTLTFLGPTLPTVVRRARFPEDEVKTAELTLARCHMSSAALRALPELARRFGVPEAA
                     TLRMAQDIEDRRAPAPGSTRRRESVRRLELALLQVKLDTLRDLRDAGRIDDIVLRAVQE
                     VLDVEEVRLGTKAHQPAAESSQDDPARS"
     CDS             7592..7792
                     /gene="allorf_026353_026553"
                     /locus_tag="allorf_026353_026553"
                     /protein_id="allorf_026353_026553"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSGVWCVQLQGGGGRRRDGGPPARAKPRAWGSRQPTTTPLGAPPA
                     RRAWGRACQTPRLRHDPPDRP"
     CDS_motif       7592..7627
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSGVWCVQLQGG"
                     /locus_tag="allorf_026353_026553_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       7628..7792
                     /prepeptide="core"
                     /locus_tag="allorf_026353_026553_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.10"
                     /molecular_weight="5827.5"
                     /monoisotopic_mass="5824.1"
                     /core_sequence="GGRRRDGGPPARAKPRAWGSRQPTTTPLGAPPARRAWGRACQT
                     PRLRHDPPDRP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSGVWCVQLQGG"
                     /leader_location="[7591:7627](+)"
                     /alternative_weights="5845.5"
                     /alternative_weights="5863.6"
                     /alternative_weights="5881.6"
                     /alternative_weights="5899.6"
     CDS             7606..7773
                     /gene="allorf_026367_026534"
                     /locus_tag="allorf_026367_026534"
                     /protein_id="allorf_026367_026534"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRPAARRRRASTRWGSPCSSEAESLGESATDDNAAGGTPCSKSLG
                     EGVPDPASPA"
     CDS_motif       7606..7716
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MRPAARRRRASTRWGSPCSSEAESLGESATDDNAAGG"
                     /locus_tag="allorf_026367_026534_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       7717..7773
                     /prepeptide="core"
                     /locus_tag="allorf_026367_026534_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.70"
                     /molecular_weight="1640.8"
                     /monoisotopic_mass="1639.8"
                     /core_sequence="TPCSKSLGEGVPDPASPA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRPAARRRRASTRWGSPCSSEAESLGESATDDNAAGG"
                     /leader_location="[7605:7716](+)"
                     /alternative_weights="1658.8"
                     /alternative_weights="1676.8"
                     /alternative_weights="1694.9"
     gene            complement(7789..8055)
                     /locus_tag="IE289_RS51830"
                     /old_locus_tag="GCM10010317_056790"
     CDS             complement(7789..8055)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013188.5"
                     /locus_tag="IE289_RS51830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_056790"
                     /product="cation:proton antiporter"
                     /protein_id="WP_229889207.1"
                     /transl_table=11
                     /translation="MPRRILTVLRAESLLNDGTALVLLAVAIEVVTDERPFSWSGTALA
                     FVESYAGGIVIGAATALLLIPVRRRLPEPLLHSVLSVATPFLA"
     CDS             8330..8509
                     /gene="allorf_027091_027270"
                     /locus_tag="allorf_027091_027270"
                     /protein_id="allorf_027091_027270"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSVLRGSPRRAAEAVHSGPYDATAGPSPVHRRRRQRSVPGFPRRC
                     RSCSWLHGRAATHG"
     CDS_motif       8330..8383
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSVLRGSPRRAAEAVHSG"
                     /locus_tag="allorf_027091_027270_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       8384..8509
                     /prepeptide="core"
                     /locus_tag="allorf_027091_027270_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.10"
                     /molecular_weight="4533.1"
                     /monoisotopic_mass="4530.4"
                     /core_sequence="PYDATAGPSPVHRRRRQRSVPGFPRRCRSCSWLHGRAATHG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSVLRGSPRRAAEAVHSG"
                     /leader_location="[8329:8383](+)"
                     /alternative_weights="4551.1"
                     /alternative_weights="4569.1"
                     /alternative_weights="4587.1"
                     /alternative_weights="4605.2"
     gene            complement(8526..9635)
                     /locus_tag="IE289_RS27565"
                     /old_locus_tag="GCM10010317_056800"
     CDS             complement(8526..9635)
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058662.1"
                     /locus_tag="IE289_RS27565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_056800"
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /protein_id="WP_190171791.1"
                     /transl_table=11
                     /translation="MITVVDIVAPADIHLGPLLVIAPAITASFAGPRLTGAIGVLALAA
                     EAGIALYDGILFSRNVVVQMVALAVLSLLIVGYSVVRERHGRELAQVRSVAEAAQHVLL
                     WPLPSGIGPLRTASVYLAAEDEAEIGGDLYAVTRTDDATRVLIGDVRGKGLAAIGEAAL
                     LLGAFREASHQHADLIALTDALEQSVGRYHGEFTPPEDEAGAEERFVTALLLEIPDDAA
                     IVRMTSCGHPAPLLLSPEHSVTALRLHPAPPLGIGVLGPSPRTLDVFTFEAGETLLLYT
                     DGVIEARNQSGDFYPFAERAAQWTESGPEALLRHIRRDLLAHVGGRLGDDAALIALRRT
                     PTHSGHHLARFIHVEPSRGWGRDSQERSS"
     misc_feature    complement(9618..9632)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            complement(10001..12895)
                     /locus_tag="IE289_RS27570"
                     /old_locus_tag="GCM10010317_056810"
     CDS             complement(10001..12895)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240676.1"
                     /locus_tag="IE289_RS27570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_056810"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_190171619.1"
                     /sec_met_domain="DUF4135 (E-value: 7.6e-74, bitscore:
                     243.2, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4.1e-41, bitscore:
                     135.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEWGGWTVSGSAPEGSERPGKPGESGRRDEAEWFARPVRTIARP
                     WREELARRLASLDALSREEQETVLEAGHTALLKSLHAKLSRLFLIELHALRMTAGGGRH
                     AEDAGAGSDTRTWTAFLEQAGEEGYLDRLTGRYPNLGPRIASVARLSVAATAGFAERLA
                     ADREVLRPLLGGPAGEMRAVAFGAGDTHRGGLTVSRVDFAGGSVMYKPRPSASDVALGA
                     LLDELYADFPSAPSPDERIRVPRTQAREGYGWAEFVRHRYCADEAELAAFYRNIGHWLA
                     VLRFTGGTDMHAENMIATGPVPVIVDAETLFDAPAPFPPSGRGDAVDVAAAAIRRTVLR
                     TGLLPVRGTGFALGGVDISGVGSLPGQQPLIPNPVIADAGTAAARFQVDLVAMPTAGNH
                     PSPTPVLSAYWDRILAGFREMTAHLRRPGTDPHRLLRRFEGAQARRILRPTQAYVDIGR
                     MLWHPASLHDEAAAVERARDILRRNAEVLPGAPTERAAIDGEIADLLAGDVPMFTFTVD
                     SAAVRTTVEDWRTADLVLEEAVIQDALVGAYLNERSLPTRTQAAARDPHARDRERRRRD
                     LAAQMVRRLCDGAVRGEDGTVTWISPVFTPAGWSIRVLPADLYTGQGGVALTLAEYVTE
                     VRAGRAEEVPGVAETFDGALRVLVGTEDRTPTPSPGAFSGAASQVWTWLALHRVLGEDW
                     LLERAAARALLLAEGRLVEDDVEVDLLNGAAGAVVPLLNLAAATGQDRWLGAAAHIGRR
                     LTGLATLDASGARWTTRLNPEGIGGFAHGATGIGWALTRLALGDAGSAAERRDWNHLAE
                     RAFAYQESLYQPEHGNWLDVRIGAEEDFFTSWCHGSAGVGIGMLDLHRRTGDPAHLDMA
                     RRAARACAAEGFGWSHTLCHGDLGLWEFLTSMDFGDPSDLDAEILTGLEQRGPVGGLAR
                     EAFSPSLMSGLSGVLHTLLRMHPAATLPNPLLLD"
     misc_feature    complement(13161..13170)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.19"
                     /tool="antismash"
     gene            complement(13235..13435)
                     /locus_tag="IE289_RS27575"
                     /old_locus_tag="GCM10010317_056820"
     CDS             complement(13235..13435)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240677.1"
                     /locus_tag="IE289_RS27575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_056820"
                     /product="DUF6229 family protein"
                     /protein_id="WP_095858363.1"
                     /transl_table=11
                     /translation="MPQTSVATTAVLDAWLAGAESAYGQTNPAGPLYVGGAAAEAALTD
                     PSDSLYGFCSSPSGSHGSWCC"
     CDS_motif       complement(13364..13435)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPQTSVATTAVLDAWLAGAESAYG"
                     /locus_tag="IE289_RS27575_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13235..13363)
                     /prepeptide="core"
                     /locus_tag="IE289_RS27575_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.60"
                     /molecular_weight="3971.2"
                     /monoisotopic_mass="3968.8"
                     /core_sequence="QTNPAGPLYVGGAAAEAALTDPSDSLYGFCSSPSGSHGSWCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPQTSVATTAVLDAWLAGAESAYG"
                     /leader_location="[13363:13435](-)"
                     /alternative_weights="3989.3"
                     /alternative_weights="4007.3"
                     /alternative_weights="4025.3"
                     /alternative_weights="4043.3"
                     /alternative_weights="4061.3"
                     /alternative_weights="4079.4"
     CDS             13448..13675
                     /gene="allorf_032209_032436"
                     /locus_tag="allorf_032209_032436"
                     /protein_id="allorf_032209_032436"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MDVGIGADCPALSIAGFEHPSDVQSGQSHVVFMRPATSHGTGGTV
                     ARPSADRAGAADAEPPTPSSGLGCAPTRSP"
     CDS_motif       13448..13546
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MDVGIGADCPALSIAGFEHPSDVQSGQSHVVFM"
                     /locus_tag="allorf_032209_032436_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13547..13675
                     /prepeptide="core"
                     /locus_tag="allorf_032209_032436_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.70"
                     /molecular_weight="3806.1"
                     /monoisotopic_mass="3803.9"
                     /core_sequence="RPATSHGTGGTVARPSADRAGAADAEPPTPSSGLGCAPTRSP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MDVGIGADCPALSIAGFEHPSDVQSGQSHVVFM"
                     /leader_location="[13447:13546](+)"
                     /alternative_weights="3824.1"
                     /alternative_weights="3842.1"
                     /alternative_weights="3860.1"
                     /alternative_weights="3878.1"
                     /alternative_weights="3896.2"
                     /alternative_weights="3914.2"
                     /alternative_weights="3932.2"
                     /alternative_weights="3950.2"
                     /alternative_weights="3968.2"
     misc_feature    complement(13518..13538)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 21.56"
                     /tool="antismash"
     misc_feature    complement(13858..13875)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     gene            14177..15181
                     /locus_tag="IE289_RS27580"
                     /old_locus_tag="GCM10010317_056830"
     CDS             14177..15181
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019075954.1"
                     /locus_tag="IE289_RS27580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_056830"
                     /product="substrate-binding domain-containing protein"
                     /protein_id="WP_190171620.1"
                     /transl_table=11
                     /translation="MRRNHRAAALAGVVLTCTLIAAGCSSSSGGKKSEERGAAASAGKA
                     DTPRMTVAMITHAAPGDTFWDLIRKGAQAAAAKDNVKLVYSSDPNAGNQANLVQNALDQ
                     KVDGIALTAAKPDALKAVAAKAASAGVPVVGFNSGLDDWKRLDMLEYFGQDENIAGQAF
                     GGRLSRLGAKHALCVIQEQGQVALEARCAGLKKGFTGKTDTLYVNGTDMPSVKATITAK
                     LRQDSSIDQVVTLGAPFALTAVQSAQDAGGKAKIATFDLNKDLVKAVQSGSVEFAVDQQ
                     PYLQGYLAVDALWLYKTNGNVSGGGTAPVLTGPAFVTKENVDTVAEFAQNGTR"
     cand_cluster    14409..35467
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    14409..35467
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[24408:25467](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      24409..25467
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="2"
     gene            complement(15342..16349)
                     /locus_tag="IE289_RS27585"
                     /old_locus_tag="GCM10010317_056840"
     CDS             complement(15342..16349)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010038097.1"
                     /locus_tag="IE289_RS27585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_056840"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_190171621.1"
                     /transl_table=11
                     /translation="MADVAEKAGVSRALVSIIFRNQPGASQETRERVLRVADEIGYRLD
                     SAARLLARGRSRTLGVMFTVHQTFHSDLIEGIYPEAERLGYDVVLSASSQGRSEAKAVE
                     ALLSHRCEALILLGPEAEPAYLEELGQRTATVSVSRRVPRARVDFVHSAEAKGIRQAMD
                     HLVEQGHRRIVHVDGGRGPGSAERRRAYRAAMRYYGLESEIRVIPGDHTERSGIETGRV
                     LLAERDSGHPLPTAVLAGNDRCAMGLLMALARAGVDVPRDMSVIGYDDSHLSHLMPIGL
                     TTVRQDAVLMAEHAVRFAVQRLEDVGLEPREAVLDPKLVVRGTSGPVPSDGPEG"
     misc_feature    complement(16435..16452)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.5"
                     /tool="antismash"
     gene            16565..17515
                     /locus_tag="IE289_RS27590"
                     /old_locus_tag="GCM10010317_056850"
     CDS             16565..17515
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019055939.1"
                     /locus_tag="IE289_RS27590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_056850"
                     /product="TIM barrel protein"
                     /protein_id="WP_190171622.1"
                     /transl_table=11
                     /translation="MAPAPSPLRTTAGNLCLGSAPDSWGVWFPEDEHQVPYTRFLDELA
                     QAGYEWLELGPYGYLPTDPQRLKAELDARGLQVSGGTAFGALHRPGAWDEMLAHVRQVA
                     ALTAAAGAHHLVLIPPMYRDEKTGEFTEPPELTAVQWAGFGRAADRLGRLLLDEYDLRL
                     VIHPHADSHIQTQPEIERLLGESDSRYTNLCLDTGHVAYGGGDNLDLIRRFGERVGYVH
                     IKQMDPAVLAQVAAENLSFGEAVRRGVCVSPPEGVPNPADVVAELAGLAAELFVIVEQD
                     LYPCAPDVPLPIAVRTREHLDGCGLSGTRRPKTTR"
     gene            17525..18958
                     /locus_tag="IE289_RS27595"
                     /old_locus_tag="GCM10010317_056860"
     CDS             17525..18958
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1169: sugar
                     transport protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009719967.1"
                     /locus_tag="IE289_RS27595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_056860"
                     /product="sugar porter family MFS transporter"
                     /protein_id="WP_190171623.1"
                     /transl_table=11
                     /translation="MDVRDDTATASTTAPRIVDDGPAAVRRRLRVISLIATFGGLLFGY
                     DTGVINGALPYMTDDLGLTPVTEGMVTSSLLLGAALGAVAGGRLSDARGRRRSILTLAV
                     LFFVGALGCTLAPTTAVMVVARFVLGLAVGGASVTVPVYLAEISPAERRGALVTRNELM
                     VVSGQLLAFTSNAVIADVGGESGGVWRWMLVIATVPAVVLWFGMLVMPDSPRWLASQSR
                     FDEAFEVLKQVRSEARARAELSEVSALAVKDEQEKLGGWRDMKATPWVRRLMFIGFGIA
                     IVQQITGVNTIMYYGTQILTDAGFTADSALTANIANGVISVLATFVGIWLLGRVDRRPM
                     LMSGQIGTTTALLLIGVFSLALPEGTGRAFAVLAMTVTFLAFQQGAISPVTWLMLSEIF
                     PMRMRGFGMGVATVVLWLTNFAIGLVFPSLVDGIGISNTFFLFVAAGVLSLTFVKRYVP
                     ETRGRTLETLEAELRTRFS"
     gene            19018..20037
                     /locus_tag="IE289_RS27600"
                     /old_locus_tag="GCM10010317_056870"
     CDS             19018..20037
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173400.1"
                     /locus_tag="IE289_RS27600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_056870"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_190171624.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 4.2e-31, bitscore:
                     102.3, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 8.6e-22,
                     bitscore: 71.6, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVRVGVIGAGMIGQDHIRRLTEAVTGARVSAVTDIDQARATEVA
                     ARVGAGALPTGADLIASPEVDAVLVTSWGPTHAEHVLNAVTAGKPVFCEKPLATTAEDC
                     LRIVEAERAHGRRLVQVGFMRRFDVGYRQMKEVLASGSIGAPLIVHCAHRNPTVPESYT
                     SVMAAQDTAVHEIDVLRWLLDDEIVSAQVITPRATGKRFAHLKDPQIMLFETANGVRID
                     LEVFVNCQYGYDIRCETVGEEGLVRLPDPAAVGVRTAGHHETAVPQDWKGRFADAFDTE
                     FREWIAAVGTGSEPTGPSAWDGYAATVITDAAVRSLESDGTVVTVDMKPRPALYGGAA"
     gene            20034..20903
                     /locus_tag="IE289_RS27605"
                     /old_locus_tag="GCM10010317_056880"
     CDS             20034..20903
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005484796.1"
                     /locus_tag="IE289_RS27605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_056880"
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="WP_190171625.1"
                     /transl_table=11
                     /translation="MKIALDPYMFRALPLDEMVRTVAELGYQYIELSPRDDFMPFFLHP
                     RADDARVADLKNSLRRHGVQLSSVLPLYKWSSPDETERQAAVRYWRRMIEITAELECPL
                     MNSEFNGRPDRAAESEAAFWRSMEELLPVFEREGIALNLEAHPDDFCEENTPAVDLVRA
                     VNKPWVNYLYCAPHSFHLSGASDVGADIAAMMRYAGDKLHHVHIADSFNHKGSSGLRYI
                     LNPPGTAARIHQHLDIGQGEVDWDAFFGTLRELNFDGVATACVFAWEERARESSAFMLD
                     RISKELSA"
     gene            complement(20999..22444)
                     /locus_tag="IE289_RS27610"
                     /old_locus_tag="GCM10010317_056890"
     CDS             complement(20999..22444)
                     /EC_number="1.2.1.12"
                     /GO_function="GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /GO_process="GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088780.1"
                     /locus_tag="IE289_RS27610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_056890"
                     /product="glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="WP_190171626.1"
                     /transl_table=11
                     /translation="MTVNDDSFTNWNNREEIAESMIPIIGKLHRERDVTVLLHSRSLVN
                     KSVVSILKTHRFARQIAGEELSVIQTLPFLQALTTLDLGPSQIDIGMLAATYKCDDRGL
                     SVAEFTAEAVAGATGVNKIERQEPRDVVLYGFGRIGRLVARLLIEKAGSGNGLRLRAVV
                     VRKGAGQDIVKRASLLRRDSIHGQFRGTITVDEANSKIVANGNEIKVIYSDDPLSVDYT
                     EYGIKDAILIDNTGRWRDREGLSQHLRPGIAKVVLTAPGKGDVPNIVHGVNHDTIKPDE
                     QIMSCASCTTNAIVPPLKAMADEYGVLRGHVETVHSFTNDQNLLDNYHNSDRRGRSAPL
                     NMVITETGAASAVAKALPDLKAKITGSSIRVPVPDVSIAILNLQLARETTREEVLDHLR
                     DVSLTSPLKRQIDFISAPDAVSSDFIGSRHASIVDAGATKVEGDNAILYLWYDNEFGYS
                     CQVVRVVQHVSGVEYPTFPAPAV"
     misc_feature    22484..22499
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.09"
                     /tool="antismash"
     CDS             complement(22603..22722)
                     /gene="allorf_041364_041483"
                     /locus_tag="allorf_041364_041483"
                     /protein_id="allorf_041364_041483"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGSARPMSSETVTGGGRNRVKGAHSCPRSGHPRREADRP"
     CDS_motif       complement(22678..22722)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGSARPMSSETVTGG"
                     /locus_tag="allorf_041364_041483_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(22603..22677)
                     /prepeptide="core"
                     /locus_tag="allorf_041364_041483_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.80"
                     /molecular_weight="2660.9"
                     /monoisotopic_mass="2659.4"
                     /core_sequence="GRNRVKGAHSCPRSGHPRREADRP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGSARPMSSETVTGG"
                     /leader_location="[22677:22722](-)"
                     /alternative_weights="2678.9"
     misc_feature    complement(22631..22647)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.3"
                     /tool="antismash"
     gene            complement(22859..22981)
                     /locus_tag="IE289_RS52860"
     CDS             complement(22859..22981)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE289_RS52860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_268256046.1"
                     /transl_table=11
                     /translation="MSSRYVSGRGWIRTKISEQGRASTPYASGKGSYGPAMDDV"
     gene            22982..24412
                     /locus_tag="IE289_RS27615"
                     /old_locus_tag="GCM10010317_056900"
     CDS             22982..24412
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013005613.1"
                     /locus_tag="IE289_RS27615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_056900"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_099924902.1"
                     /transl_table=11
                     /translation="MTVPESSPESAAGPTADGPRSTSLSTDAARQLATTTKSEPQMQAI
                     TSRWLLKMLPWVDVKGGAYRVNRRLQLRVGRGRVQFEQNGADDIRVIPETLTELPALRG
                     YSDTAALQEISSRFRVREVRTGQVLFDAGQPVTEAYLVVHGRFTRYTTGKYGEQEVTGV
                     ITDGDGMGDEAIGQADPLWFGSVRAETPGVVLALNWDTLMAFVERTPSLAAQLDAFAQQ
                     QSKPMNRKGEADVPVQAGHVGEPVLAGGFVDYDLAPREYELSLTQTVLRVHTRVADLYN
                     HPMNQTEQQLRLTIQEIRERQEWELVNNREFGLLHNVDYGQRVSTFSGPPTPDDLDELL
                     SMRRKTRLFLAHPKAIAAFFRQCNRRGLVPGTVNLDGHEVPAWRGVPLFPCSKIPISPQ
                     HTSSIIALRTGEKDQGVVGLHQTGIPEEYEPGLNVRFMGIDSTAIMSYLVTAYYAMAIL
                     VPDAAGILENVQVGRTAE"
     gene            24409..25467
                     /locus_tag="IE289_RS27620"
                     /old_locus_tag="GCM10010317_056910"
     CDS             24409..25467
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020126202.1"
                     /locus_tag="IE289_RS27620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_056910"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_190171627.1"
                     /sec_met_domain="T1TS (E-value: 2.4e-56, bitscore: 186.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTPSVSGSPTRLPGPPRLVPVTQTRRSGAIPGLRHRPAAPADPG
                     KAAEVDRRLEAWVRRLDAFPKAWTGDFAGFQFGRAVVLQHPGAADLERLTTAGKLLLAE
                     NLVDNCYCEEDEDRGGSSRGLGGRLIRAQSALDPFHSTPELEARWRRGVQADGPLRSYH
                     GALKDYAVFATPSQTDRLVHDLARLHLGYLGEAAWAEIRYVPPVWEYLMMRQFNNFRPC
                     LAIVDAVDGYELPEALYVRPEIQRITALAGNATTIVNDLYSFTKELANDPSHLNLPQVI
                     AANERCGLKAAFLKAVEIHNQVMEAFEEEAAALSATSPLVERYAGGLAAWVSGNHEWHA
                     TNTHRYHLPNYW"
     gene            25551..26426
                     /locus_tag="IE289_RS27625"
                     /old_locus_tag="GCM10010317_056920"
     CDS             25551..26426
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981046.1"
                     /locus_tag="IE289_RS27625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_056920"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_190171792.1"
                     /transl_table=11
                     /translation="MPTQATCQSTYQTRVADYWNAEENPVNLELGKIDDLYHHHYGIGD
                     VDRSVLDEGRHGGGDGDGAAMRRDRITAELHRLEQAQADLLASHLGPLSRADRVFDAGC
                     GRGGGSVVAHLRYGCHTDGVTISRKQADFANAQARTRNIDDKVRYHHRNMLDTGLPSGA
                     YAASWNNESTMYVELDLLFAEHARLLRRGGRYVTITGCYNDAYGRASREVSLINAHYIC
                     DIHPRSEYFRAMARNRLVPVHVQDLTADTIPYWELRKQADHLVTGIEETFLSAYENGSF
                     QYLLIAADRV"
     gene            26523..28088
                     /locus_tag="IE289_RS27630"
                     /old_locus_tag="GCM10010317_056930"
     CDS             26523..28088
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018561.5"
                     /locus_tag="IE289_RS27630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_056930"
                     /product="DUF1254 domain-containing protein"
                     /protein_id="WP_190171628.1"
                     /transl_table=11
                     /translation="MSEATHPTHHRPLRRTHDDAAGVTATINRAASAAGAAGRAAADAV
                     RHPQAVVDRLRHLPQTLPLVRQAVTPILTGRVRDWRGEYAYTLGEQAFVYGFPYIYNAR
                     LRHQWVTQPRDPATVPYAAVNHFWHAQQLLDASYRDGGCPNNDTLYSTAWVNLRDEPVI
                     LSHPDMGDRYFSFELMGITSDNFDYIGQRSTGSEAGHFAIVGPDWSGKLPDGVRRVATA
                     PSPWILILGRTLVDGEDDVPNVQTLQAQYRLTPLSFFDRGGGPVDPALLPASHEVPAPV
                     DPAQDPLGPWKTLNAMLAENPPPAHHAILLKQFAEVGIGPGLDVEAQPEAVRQNLIRAA
                     AVGTPMLKQQMLSGEWAHVVNGWRYPPPQIGRFGDDFVKRAADQSLAGIMANDPDEAVY
                     LLNYDDADGNKLSSGRYALRFDAGAMPPVDAFWSLSAYGDDMNLIPNPADRYSVGDRTT
                     GIAMDPDGGLTLHLQPTSPGEDRESNWLPTPETGTWFVILRMYRPHREVVDAVWECPPL
                     TRVE"
     gene            complement(28146..28511)
                     /locus_tag="IE289_RS27635"
                     /old_locus_tag="GCM10010317_056940"
     CDS             complement(28146..28511)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006382117.1"
                     /locus_tag="IE289_RS27635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_056940"
                     /product="hypothetical protein"
                     /protein_id="WP_190171629.1"
                     /transl_table=11
                     /translation="MHTLKRKVATAALVAGALFGGLAVPGTAYAANKYVQLKVCSGSTE
                     TVKFYFVGENQYGDWGGSRFWEIAPKGCTVADGYWWIAGQSVEFHHRKPSTGWRWEPRL
                     ISANDTSNGATYQLYIG"
     gene            complement(28640..29206)
                     /locus_tag="IE289_RS27640"
                     /old_locus_tag="GCM10010317_056950"
     CDS             complement(28640..29206)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010358308.1"
                     /locus_tag="IE289_RS27640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_056950"
                     /product="hypothetical protein"
                     /protein_id="WP_229889208.1"
                     /transl_table=11
                     /translation="MGASLLVAPQAFAASSPTNAELLKACNWASLCKFHPQSYWGYTGP
                     KHQVGSTAYNCGSNTNQHRIDWSDTTTAGNTVGVSVSATYKFSLVFEASVETSYSHSWE
                     NSHTDTESNTINISPRSVGWLERGTSKQQAKGWWEIQFKNKYYDHYVWYIYDFQQSGFN
                     KDNPSYGYVNFKDRPMTPAEIGAHC"
     misc_feature    complement(29248..29262)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.74"
                     /tool="antismash"
     misc_feature    29249..29263
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.0"
                     /tool="antismash"
     gene            complement(29491..29829)
                     /locus_tag="IE289_RS27645"
                     /old_locus_tag="GCM10010317_056960"
     CDS             complement(29491..29829)
                     /GO_process="GO:0050898 - nitrile metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018562103.1"
                     /locus_tag="IE289_RS27645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_056960"
                     /product="nitrile hydratase accessory protein"
                     /protein_id="WP_190171630.1"
                     /transl_table=11
                     /translation="MTAPLDIDGTAAPPRANGELVFSEPWESRAFGMAVTLYEAGAFTW
                     PQFQGALIARIAAWENALDQDRPWSYYHHWLAALEDVLDEQGTVSCDEVATRALILARR
                     PAGHDHHH"
     gene            complement(29826..30425)
                     /gene="nthA"
                     /locus_tag="IE289_RS27650"
                     /old_locus_tag="GCM10010317_056970"
     CDS             complement(29826..30425)
                     /EC_number="4.2.1.84"
                     /GO_function="GO:0018822 - nitrile hydratase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046914 - transition metal ion binding
                     [Evidence IEA]"
                     /GO_process="GO:0050898 - nitrile metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="nthA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016438073.1"
                     /locus_tag="IE289_RS27650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_056970"
                     /product="nitrile hydratase subunit alpha"
                     /protein_id="WP_099924897.1"
                     /transl_table=11
                     /translation="MTTSSESGEAPSAALRTEALEQLLTERGLIDPKIVDAFITNYETN
                     VGPLNGAKVVAKAWTDPEYRRRLLADGTSAIKELGFGGPQGEHIVVVENTPTTHNVVVC
                     TLCSCYPWPVLGLPPSWYKDPVYRARVVKEPRTVLSEMGLDLGDDVQITVRDSTSEVRW
                     LVLPERPAGTEHLTEEELVPLITRDAMVGVAKVAAA"
     gene            complement(30422..31126)
                     /gene="nthB"
                     /locus_tag="IE289_RS27655"
                     /old_locus_tag="GCM10010317_056980"
     CDS             complement(30422..31126)
                     /EC_number="4.2.1.84"
                     /GO_function="GO:0018822 - nitrile hydratase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046914 - transition metal ion binding
                     [Evidence IEA]"
                     /GO_process="GO:0050898 - nitrile metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="nthB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018562101.1"
                     /locus_tag="IE289_RS27655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_056980"
                     /product="nitrile hydratase subunit beta"
                     /protein_id="WP_190171631.1"
                     /transl_table=11
                     /translation="MEGVADMGGTSGWGSARRPRADEPVFAEPWQGRAAALTILATRVS
                     GRNVDAFRHAQERLDRAAYLDEGYFGRWLNAAELMLIEGAILAPGEINARARDLRGEHV
                     ENRPVSVSVPESARPDADPPTAAIAAWRSAPGSLRTIDAAPAFAVGQRVRAKNISPPGH
                     TRLPGYVRGHAGVVEVIQPAAVFPDTHAHFLGENPQHVYSVRFDSHELWGEGADSFAVT
                     VDLFENYLETTS"
     misc_feature    complement(31271..31287)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.6"
                     /tool="antismash"
     gene            complement(31301..33394)
                     /locus_tag="IE289_RS27660"
                     /old_locus_tag="GCM10010317_056990"
     CDS             complement(31301..33394)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018524877.1"
                     /locus_tag="IE289_RS27660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_056990"
                     /product="FUSC family protein"
                     /protein_id="WP_190171632.1"
                     /transl_table=11
                     /translation="MTPGPGGAAILRRSIQVTCSASVGFYTFLYGLQQPVAALYALFTP
                     IAFGLLSTIPGTGRQQAWITLRTLPFGVVFVALGTALAVSTAAAVAGMLIVGFLLSFTV
                     VAGPRTAGPAPGLQLLYILACFPPYAPQTLGARLTGVAVGVVLLSLCQVFVLSGPPATS
                     YRTVLADALETAAAAAVDPARVSVARLRDLSEGMRLSQVSPGERPTGPGRRDRALAQAG
                     AAVRRVVDQLASRSTTSLPPGAAPRTDPSSAALRERVARTCEDTGAALRAGERPPTADA
                     LDKAIRQFQAERIRRAADPGEPGVDTDVLRRQAAELTLAESTWIAVTAVGVSAAGRRTS
                     PLRPRELFWYADLPTTQLWARRVVGNATHRSVWFQNAVRVACGLAIARLVAGTLDLAHG
                     FWVLLAVLTLGRTTVGATWRAVRQAMIGNLVGAVAAGALLIALGRHLDAYAVLLVPGML
                     IAFALGPRLGIAYAQGLFTLVVTLAFAQITPTSWRLSEARIVDVVTGSVIGLLCGLLAW
                     PAGARREVHRTMAGLLRSCGTLVPATVEALLAPSAAAPSPPATLPTLRHLRLAEAAYAQ
                     FRSEPPTAWEGAQADWHGVLIVAYHTVLGAQRLPCFEAPLAEVPPDARAWVRGTAAELT
                     TDADRIATYFTTDERPAPGRSPPGPPLPEHHPALPTLIDLEVWLTDIDHQLARIEDSVG
                     PKT"
     gene            complement(33694..34914)
                     /locus_tag="IE289_RS27665"
                     /old_locus_tag="GCM10010317_057000"
     CDS             complement(33694..34914)
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016430562.1"
                     /locus_tag="IE289_RS27665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_057000"
                     /product="carbohydrate-binding protein"
                     /protein_id="WP_190171633.1"
                     /transl_table=11
                     /translation="MRRLRACLGAAAAVGLAAAGTTALVAGSASGATSALGNRWYAAAP
                     YLMPLDNDPPDPATIMDATGLKAFQLAFVLAPNGGGCSPTWGGTAAVSSDTAVQSVVNT
                     IRAKGGDVSVSIGGYGGTKLGQVCSDAAATAAAYQQVITKYGLHAIDFDLEEPEYENTA
                     AIKNEIGAAKILQQNNPGLYVSVTTAGTADGTGWFGKQMLLEAKSQGFTPNNFSIMPFD
                     GGFNGAASQTSALTNFNQILQSTFGWDQATAYAHEGFSGMNGRSDTGEFFTQTDFQTVL
                     DYATSHNMDRFTFWSLNRDRQCTPADNGGRTSGTCSSVAQNSWDFAKYSVKFAGVTPPS
                     STPTPTPTPTPTPPSTGCKPAWSSTAVYTVGNEVSYNNHNWKAKWWTQNETPVASDWGV
                     WQDEGAC"
     misc_feature    34982..34997
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 23.43"
                     /tool="antismash"
     misc_feature    35003..35018
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.85"
                     /tool="antismash"
ORIGIN
        1 gacatcacct cggtcgcggc ggtgcgggcg ctgcgccagg cggaaccgaa actgagcctg
       61 ctggcggcgg tgcaactgca gaaggaggca gtggcccatc cggagtgatc cggcagcccc
      121 ctgacacgcg gggaacggag gctgccggag gcgttgcgct gctcaggtgg tgcggtagca
      181 ggtcttgctc acgcccggca gcggatcggt gccgaatgcc gccgtcgtgc agccggtgcc
      241 gccggtgaac gccttgtaga ggaaacggcc ccgggcgccg taggcgacgg tctgctgtcc
      301 gctgaaggcg cacgtgccgc cttcggcgga gcaggaggcg gcgtagccga ccggaccgcc
      361 ggtggcggtg tagcaggcct tcgactcacc cgggatcgga tctccgaacg tggcgtcggt
      421 gcacggggtg tcgccggtgg ccgtgatcgt cgtgaacgct ccgaaggcgc cgtatgtcac
      481 cggctgcccc gcggcggccg ggcaggttcc gttctggtcc gcacacttgg tccagccacc
      541 ggacggtcct cccgcgggcg ccacgtagca ggacttggcc actccgtcga tgggatcgcc
      601 gaagtgggcg ttggtgcagg cgacggaccc gttggtgacc tggtgggcga agttgccgtt
      661 ggcgccgtag acgacgtcac ggttgtagcc gggcacggcg caggtgccgc cctccgccgc
      721 gcagacggtg tatccgggcg ggccgcccgc gtcggcgacg tagcaggact tgacgagatt
      781 cgacgccggg tcgccaccga aggagtcgtt ggtgcaggcg gtgctgccgg tcactgtttt
      841 gtacgtgtag gtcccagccc cgtaggccac cgagcgggtg ccgctgaagg agcaggtacc
      901 gccctcgccc gcgcaccggg tgaagcccgg ccgcagcgcg ccggtaccgg gatcggcggg
      961 cggcgacgga ttgcccagtc cggtggcggc cacggtgtag ccgcccgggg cgacgccggt
     1021 gaggtagacg taggtgtcgt cctggctcgc gccggtgatt cccgaggtgg gggtgaacgt
     1081 tccgttgctc cagacgacgg tgccgttcac ggacaccgag atgttgccgc cgaacttcgg
     1141 gacgccgatg cggccggtgg tgccggccgg gctggtgagg tgcgccgagt acgtgccggc
     1201 ggcggggtcg cgggaccagg aggcgttgac ggcgccctgg ggcatggtga tgcggccctc
     1261 ggcgctggtc aggtcgcctg ggtgcgggac gaaacggtac gtgccggtcg ccgactcggg
     1321 tgcggtgccg agcacgtcga aggtgagcgt ggaggtgggc gcggtggacc agccgtgggc
     1381 caggctcatg aacgaaccac cgtaggcgag gccgccgtca gccttgatgc cctcccagaa
     1441 ggtgctcttg gtgccgatgt cgctggtcag catgtggccc caggtgcggc ggatctggtc
     1501 cagggcggtg tagtcgtcat tggcggtgaa gcgggcgttg agctccatgc cgccggcgaa
     1561 gggcgacacg ttgccgcccc attcgggggt cgtgggaccg tagatgcccc agttcttccc
     1621 gagccccgcg atgacactct tcgacttggc cgcggagtcg gtcaacccgt accagacggc
     1681 gagggagttg ccgtcctgcg ggtacaggcc gctgctgggg ttgtccttgt acatgccctt
     1741 cgcggcgtcc cacagcaggg agttggcggc ggacttgatg gcggccgcct tggcgttcca
     1801 gctcgcggcg agtgcgctgt cgccctcgac cgtggccagg gtggcgccgc ccttgagcgc
     1861 ggcgtacagc agcgcgttgg cggagacgtt ctcgccgccc tggccgaccc gggcccagtc
     1921 ctgggtgcgc gtcacgttaa gcaggttgtt gccgtcgatc ttgttggtga tgaaggccat
     1981 cccgcgcttg tagtcggccc attcggagtc cagccacgcc cggtcggccg agtaggtgta
     2041 gtacgtcgac gtccccagca gcgtccaggt gtgataggtg tccgagccgg tgaggttgaa
     2101 cggcggcccc gaccagggga tttcaccttc cgccgactgc gcgttgtaca tcgtggtgag
     2161 cgcgttgcgg gtcgagacga ggtcgttgga gtacgcgtac tgcgtgggta cggcgatgcc
     2221 catgtcgccg ggccacaccg tacggtcgcg tttggccccg tcgaccagga cggagtcacc
     2281 cacgccgacg gtggcgccgt tgtcccacgc cgaggacggc gggggccagg cgcggccctg
     2341 gttggaggcg atcgtgttga gttggacggt gtacgccccg gcgtaccaga tgcggttgag
     2401 aaggtcgtcg ctggaggaga agtagttggc gtagtcggcc gggtcggcct tgcccggagc
     2461 cgcggtgaag ttgaggctga cgcccttgag atccacccaa cccgaggtgt ccaggaagac
     2521 cgtcaagtag cggaagccgc cccgctgttg agcggtgggc accgtgtagg tgccgttggc
     2581 ggaggccgtg gcgtagagcg ccccgtcctc gccgtcgcgt ccgctgctgc ggtcgctgtt
     2641 gttgcccacg tacagggacg actcgctgaa ggccaggccg acgcgctggc cgctgtcgct
     2701 ggtactgccg aaggacaacg ttgtcacgcc accgacctct ttgccgaagt cgagggtgac
     2761 ggccgactgc gagccggaga tccgcgtcgg ctgcccgctg aggacgttct gcgggttcgc
     2821 gacactgccg gacgttcggt agatcgccgt cggcttgagg gtgcgcgagg tcggcgagta
     2881 gttcagggcg tcaagggtcg ccttgccggc tcctgttgcg gtcgacgagg tggccgccga
     2941 tgtggccggc gcgggagcca tgagcagtgc ggcggacacc actgtggcga ggccaagtag
     3001 gcgccctggg cagggcgttc ggatcaacaa ggggcggcgg cgccgcatag gtacctcccg
     3061 ggtctgaatg cgggaacgaa gtgcttgaat cgattcaaac tgatcgctga cgaaggcctg
     3121 ggactcatga agcggtgggt gtgcgagacg cctcgccgaa gttccaccga tgatgtgcgc
     3181 cccacagcgg ggtgtcaacc cgtcacagct ggtgtgaacc acccctggaa tcactcccgt
     3241 tggagacatt gacagcaccc caccaagccg gttcactgcc tcccgggcag gtatggacca
     3301 ttgccggtcc cccgtccggc tcagtgagac ccaaccggcg tcccccaccc tgaaatcgag
     3361 gcgagttccg gtgccctcac acaactccga catcgttgtc agaccacggc tcctcacctt
     3421 cctgctgacg gccgctctcg cgttcgtggc actggtcccg gccgcgacgc cggcggccgc
     3481 cgcaacccag gtgtgcgtac tggcctgtga cacgctggac ccctcacagg cccggcagga
     3541 gagcttcccg gtgccgaaca aggacctcaa cggccgtcgc ctcgaactgc acgtgtccga
     3601 cgcggacgac atggcgtggg ccagcatcga caacggcgtg accggcgact cggtgtggct
     3661 ggaccgctcc tgggacggcg gcgccacctg ggaaggactg ctcggcaagg cgagcgtccc
     3721 gggaacctgg accggtacca ggacgctgat gtacaacatc accgatcctc gcaaccaccg
     3781 gcgcgggctc gtgcgggcct gcggcgacgc cgcaggggtc ggctgtacga actgggtcta
     3841 ccccacggtc tgcgacacgc tctgtgacgg caccgacgcg ggcaaggcgg ccggcgacga
     3901 ccagccggtg ccgtcgacga ctctctacgg ccgcacgatc cggctgcacg tcgaccagaa
     3961 gaactccctg gcctgggcga gcatcgacac cggtggcgcc ggcgacgaga tctggctcga
     4021 ccgctcctgg gacggcggct cgacctggcc ggacggctcc tcgctcggcc gcaccagcac
     4081 cccgtccggt gccaccggca cccgtaccgc gatgtacgcc acccgcgatc cgcgcgggct
     4141 gctctacggc ggcgcggtcc gcgcctgcgg ccgggaggcg agccacaacg agggcagttg
     4201 caccgcgtgg gtcagacccg tgccgaccag gacgcgcgcg gcggccgacg cgctgatgtc
     4261 ctcgtacgac ccctacaacg gctggtggcc gagcagttgg tggaactccg ccgccaccct
     4321 caccgcgctc atcgactcct cccgggccac cggcaggcac gactacgact gggtcatcgc
     4381 ccgcaccttc gaccagaaca agggcacctt cgcggccggt gttcgcagtt cggatgcgat
     4441 cgagggcgac ttcatcagcc gttccatcga cgactcgggc tggtgggcca tcgcctggat
     4501 cgacgcgtac gactacaccg gtgactcccg ctatctgaac gaggcggtca ccatcgccaa
     4561 ctacgtccag cagtactggg accccggcac ctgcgggggc ggcgtgtggt gggaccgcga
     4621 gcgcacctac aagaacgccg tgacgaacgg gcagtacctc tggctgacca cggcgctgca
     4681 ccagcgcatc gcgggcgaca ccgtttggct gcagcgggcc aagacgtccg ccgcctggta
     4741 ccggtccagc gggatgatca actcctccgg tctggtgaac gacgggctga cctccgcctg
     4801 cgccaacaac ggctccaccg tgtggagtta caaccaggga ctggccatcg gcggcttcac
     4861 cgaactgtgg aagacgaccg gggacagctc gctgctgacc accgcgcgca ccctggccga
     4921 cgccgcgatc agcagcccga cgctgacctc cggcggagtg ctcaccgagt cctgcgacgt
     4981 cggctcggcg tcctgcgacg acaaccagaa gcagttcaag ggcatcttca tgcggaactt
     5041 cgccgacctc gcgaaggcca ccggttccgg cacctaccag agttacgtcc agaagcaggc
     5101 cgacacgctg tgggcgcggg accgtagctc cctcaacgcc ctcggcgaac gctgggccgg
     5161 taccagcccc aaccagaccg actggcgtac ccaggccggc gccctcgaag cgctcaccgc
     5221 cgccgcgggc tgacgaccgg ttccgggagc cggctcgcac gcgggtcccc gacccacgcg
     5281 cgagtcggcc gacgcgagcg cgctcggccc tccacgactc gacgagctcc tccggcgcct
     5341 cgccgaacag ccccggctac ggccgcggct ctcgcaggtc cgccaacagg tcgccggtgg
     5401 cacttcccaa gcgtggtccc gggcaagccg atctcgaacg cacggcatgc cccagtaact
     5461 caaccggcac tgcatgccgg ttcgcaccgc gcacaatgtg gcacctcccg ccctcgctgc
     5521 acgagccgag ggcctcacca gccgtggatc acagcgatca ggagatcggc gtcgtgagac
     5581 tcgcaggcag aggcgttggc gacccaccgt cgccgggatc ccgggccgtt tcccactgtc
     5641 cgatgggttc ccacgcctac cctgcctgcc gccaatctac ccaccgacaa catttccctc
     5701 cttgacaatt ttttttgtcg gagagattct ggagcggtgc tggacgtcgc tgtgatcgaa
     5761 gacccgccgc ggccgaggcg tccctggacc cgatgcgggc ccggatcctc gccgcccggc
     5821 cccggcacgg aaccgcaccg gcctccctcc gggggcggcc cgcaaagagt ccccaccagg
     5881 aggccgccgc ctcgaacgtg gtcgaagcgg cggcgagcaa tcgaaaaccg cacaccagaa
     5941 tccccaaagg aaaccagcat gcgtaccctg atcagctccg ccttcatctc gctcgacggc
     6001 gtcatggagg gcccgggcgg cgaacccggc taccgcaact ccggatggac cttcaaggac
     6061 gtcgagttcg tccccgaggc gttcgacatc aaggcacggg aacagcagga atccaccgcc
     6121 gtcctgatgg gccggaccag ctacgaggcg ttcagcccgg tgtggccgga catgaacgag
     6181 ttcgcccact acaagaccat gccgaagtac gtcgtctcca ccaccctcac tgaggacaag
     6241 ctcgtctcga actggggcga gaccagcatc ctgcgctccc tcgacgaggt cgccgccctc
     6301 aaggagaccg acggaggccc gatcatcgtc cacggcagcg tcgccctgaa ccacagcctc
     6361 gccgacgccg gcctgatcga ccgttaccac ctgctcgtcc acccgctgct gctcggcgcg
     6421 ggcaagcgcc tcttccccgc caccgacaag gacacccaga agctcaggct cgtcgagcac
     6481 gccgtgtact ccaacggcct gcagatgaac gtcctcgacg tcgtccgctg accaagccca
     6541 gaggctttcc acgccgcggg acacgatcac cgcacacggc cttgatccac ttccgaagag
     6601 cgccctagga gcgcgcgggg tcgtcctggg aagactccgc cgctggctga tgcgcctttg
     6661 tccccaggcg gacctcctcc acatcgagca cttcctgaac ggcgcggagg acgatgtcgt
     6721 cgatgcggcc ggcgtcgcgc aggtccctga gtgtgtccag cttgacctga agcagggcga
     6781 gttcgaggcg ccgcacgctc tcacggcgtc gcgtggagcc gggagcgggg gccctacggt
     6841 cctcgatgtc ctgggccatg cggagggtgg ccgcctcggg gaccccgaac cgccgcgcca
     6901 actccggtag ggcgcgcagg gcggcgctgc tcatatggca acgggcgagg gtgagttccg
     6961 cggtcttgac ctcgtcctcg gggaagcggg cccggcggac cacggtcggc agcgtcggac
     7021 cgaggaacgt aagggtgacg acgatgacga cagccgtgat gaacacgacg gcgtcgcgtt
     7081 gttcgacgac ttgtccctcg gctgtcacgg cgggcacggt cagcgccgcg gccagcgaga
     7141 tggctccgcg cattcccgcc cacgccagcg gcagccgctg aggggcggtg atacggcggt
     7201 cccgctgctg aggacgccgg tccaggaacc tgaccagata ggggaccgag tagaaccaca
     7261 gcagccgtgt cccgatcaca gcgacgctca cggcgcaggc ggcgatcgcc gcctgcgcca
     7321 gggagaccga ggtcaatgcc ctgatcgcgg cgggcagttg gataccgacg aggatgaaca
     7381 gcgcgctgtt gagcgggtat ctggccactt cccagaaggc gatggcctgg atgcgggcgt
     7441 cggaaccgat gacgcggggg ccgaaccggg tggtcacaag gccgcaggtg acgccggcga
     7501 ggacgccgga cacgtgcagg agttcgacgg gcaggtaggg cctgtccggc ggatcaggtc
     7561 ggaggaaagt agcgccgcct cataagcgca ggtgagcggg gtctggtgcg tccagctgca
     7621 aggcggagga gggcgtcgac gcgatggggg tccccctgct cgagcgaagc cgagagcttg
     7681 ggggagtcgg caaccgacga caacgccgct gggggcaccc cctgctcgaa gagcttgggg
     7741 gagggcgtgc cagaccccgc gtctccggca tgatccgccg gacaggccct aggcgaggaa
     7801 gggggtggcg acactcagca cgctgtggag caggggctcg ggcagccggc gcctgaccgg
     7861 gatgaggagc agtgcggtcg cggcaccgat cacgattccg ccggcgtagg actcgacgaa
     7921 ggcgagcgcc gtaccggacc aggagaaggg tcgctcgtcg gtgacgacct cgatggccac
     7981 ggccagcagg accagagcgg tgccgtcgtt cagcaggctt tcggcgcgca gcacggtcag
     8041 gatgcggcgt ggcatggcct tgggccacgg cggcgacggc cgcggcgtcg gtcggagcca
     8101 ggactgcacc gaggacgaag gcgatgggcc agctgtagcc caacgcgtgg gccacggcgg
     8161 ccactgcgac ggcggtggcc gacaccagcc cggtggcctg tagggcgatg ctgcgggaag
     8221 ttgtcgcgga tctcgcgtac cgaggaggtc agcgcctccc agtacagcag ggcgggaaga
     8281 aagaggaaca ggacgacgtc gggggacagc gtgaacccgg cgaagggggg tgtcagtcct
     8341 acgaggcagc ccgcgccgag cagcagaggc ggttcactca ggcccgtacg acgcgacagc
     8401 cggcccatcg ccagtacacc gacggcgacg acaacgatca gttccaggct ttccacgtcg
     8461 gtgccgttcg tgttcgtggc tccacggtcg cgccgcgacg cacgggtaac caggccagga
     8521 ctttctcagg agctgcgttc ctgggagtcc cgcccccacc ctctggaggg ctcgacgtgg
     8581 atgaacctgg cgaggtggtg gccggagtgg gtgggcgtcc ggcgaagggc gatgagcgcg
     8641 gcgtcgtcgc cgaggcgtcc accgacgtgg gcgaggaggt cacgccggat gtgacgcagg
     8701 agcgcttcgg ggccgctctc ggtccactgg gcggctcgtt cggcgaacgg atagaagtca
     8761 ccgctctgat tgcgcgcctc gatgacgccg tcggtgtaga gcaggagggt ttccccggct
     8821 tcgaaggtga acacgtccag cgtgcgcggc gatgggccca ggacgccgat tcccagcggg
     8881 ggcgcggggt gcagcctcag tgcggtgacg gagtgttccg ggctgagcag caggggcgcg
     8941 gggtgcccgc agctggtcat cctgacgatg gcggcatcgt cggggatctc gagcaacagg
     9001 gcggtcacga agcgctcctc ggccccggcc tcgtcctccg gcggggtgaa ttcgccgtgg
     9061 tagcggccga cgctctgttc cagcgcgtcc gtcagcgcga tgaggtcggc gtgttgatgg
     9121 gaggcttcgc ggaacgcgcc gagcagcaga gcggcctcgc cgatggccgc caagcccttg
     9181 cctcggacat ctccgatgag tacgcgcgtg gcgtcgtcgg tacgcgtgac tgcgtagagg
     9241 tctccaccga tctcggcctc atcctcggcg gccagatata ccgacgccgt acgcaggggg
     9301 ccgatcccgc tgggcagcgg ccacagcagt acgtgctgtg cggcctcggc gaccgatctc
     9361 acctgggcca gttcccgtcc gtgtctctcg cgtaccacgg agtagcccac gatcagaagg
     9421 ctcagtacgg cgagggcgac catctgcacg acgacgttgc gcgagaagag gatgccgtcg
     9481 tacagggcga tgcctgcctc ggccgcgagc gccaggacgc cgatcgcccc ggtcagccgg
     9541 gggccggcga aggatgcggt gatcgccggc gcgatcacca gcagcgggcc caggtggatg
     9601 tcggccgggg caacgatgtc gacgaccgtg atcatcacga tcagcaggac ggggagcgcc
     9661 agcagcacat acttcgactg ccccgggccg aagccggcaa agcgatccca aatccccaca
     9721 tgttccacag tgcaccgccc caggacagct tgcgagcgca gccgagaact atcggcaatg
     9781 cgccggcagg actgccgagc gcgtcccgca cgcgccggac cacgcgtcga cgggaccgac
     9841 cccgcaccgg cgcccggcgc ggggtcggca gggctgccgc ccggccccca accgcatgcg
     9901 accaggggct cacgctgccc gtccggcgtc gcgttcacca cggtggccgc ccggtcggac
     9961 acggagcgcg accacctcgg cgaccacgcc cgaggtcggg tcagtcgagg aggagggggt
    10021 tcggcagggt ggccgcgggg tgcatgcgca ggagcgtgtg gagtactcct gagaggccgg
    10081 acatgaggct gggcgagaac gcctcgcggg ccaggccacc gaccgggccg cgttgctcga
    10141 ggccggtgag gatctcggcg tcgaggtcgg aggggtcgcc gaagtccatg gacgtgagga
    10201 attcccagag gccgaggtcg ccgtggcaca gggtatggct ccagccgaag ccctcggcgg
    10261 cgcaggcacg tgcggcccga cgggccatgt cgaggtgggc gggatcgccc gtgcgccggt
    10321 ggaggtcgag catgccgatg cccacccccg cgctgccgtg gcaccagctg gtgaagaagt
    10381 cctcctcggc gccgatgcgg acgtcgagcc agttgccgtg ctcgggttgg tagagggact
    10441 cctgataggc gaaggcccgc tcggcgaggt ggttccagtc gcgccgttcg gccgcggagc
    10501 ccgcgtcgcc gagcgcgagc cgggtcagcg cccagccgat gccggtggcg ccgtgggcga
    10561 agccgccgat gccctcgggg ttgagccggg tcgtccagcg ggcgccgctc gcgtcgaggg
    10621 tggccagccc ggtcagtcgg cggccgatgt gcgcggcggc gccgagccag cggtcctgcc
    10681 cggtcgccgc ggccaggttg agcaggggga cgaccgcgcc tgccgccccg ttgaggaggt
    10741 ccacctcgac gtcgtcctcg accagtcggc cctccgcgag cagcagggcc ctcgcggcgg
    10801 cccgctccag cagccagtcc tcaccgagca cccggtgcag cgccagccac gtccacacct
    10861 gcgacgcggc accgctgaac gccccgggtg acggcgtcgg tgtccggtcc tcggtgccga
    10921 ccaggacccg cagcgcccca tcgaacgtct cggcgacgcc cggcacctcc tccgcacgcc
    10981 cggcccgcac ctcggtcacg tactccgcga gcgtcagcgc caccccgccc tgcccggtgt
    11041 agaggtcggc gggcagcacc ctgatcgacc accccgcggg ggtgaagacg gggctgatcc
    11101 aggtgaccgt gccgtcctcg ccgcgcaccg ccccgtcgca cagccgccgt accatctgcg
    11161 cggccaggtc gcggcggcgg cgctcccggt cccgggcgtg cgggtcgcgg gcggcggcct
    11221 gcgtccgcgt gggcagcgaa cgctcgttga ggtacgcacc gaccagcgcg tcctggatca
    11281 ccgcctcctc cagcaccagg tcggcggtgc gccagtcctc cacggtggtc cgtacggcgg
    11341 ccgagtccac ggtgaaggtg aacatcggca cgtcaccggc caacaggtcc gcgatctcgc
    11401 cgtcgatggc cgcacgctcg gtcggcgcac cgggcagcac ctcggcgttg cgccgcagga
    11461 tgtcccgggc ccgttcgacc gccgccgcct cgtcgtgcaa cgacgccggg tgccagagca
    11521 tccggccgat gtcgacgtac gcctgcgtcg gccgcaggat ccgccgcgcc tgggcgcctt
    11581 cgaagcggcg cagcagccgg tgcggatcgg tcccgggccg acgcaggtgc gcggtcatct
    11641 cgcggaagcc ggccagaatc cggtcccagt acgcgctcag cacgggagtg ggactggggt
    11701 ggttgcccgc ggtgggcatc gccaccaggt ccacctggaa acgggccgcc gcggtgccgg
    11761 cgtccgcgat caccgggttc gggatcagcg gctgctggcc gggcagcgac ccgactccgg
    11821 agatgtcgac cccgccgagc gcgaagccgg tgccgcgtac gggcagcagt ccggtacgca
    11881 gcaccgtacg gcggatggcc gccgcggcca cgtccaccgc gtcgccccgg ccgctgggcg
    11941 ggaagggcgc gggggcgtcg aagagcgtct cggcgtccac gatcaccggc accggacccg
    12001 tggcgatcat gttctccgcg tgcatgtcgg tgccgccggt gaagcggagg acggccagcc
    12061 agtgccctat gttccggtag aacgcggcga gttcggcctc gtccgcgcag tagcggtggc
    12121 ggacgaactc ggcccagccg tagccctcgc gtgcttgtgt ccgcggcaca cggatgcgct
    12181 cgtcgggcga cggtgcgctg gggaagtccg cgtagagctc gtccagcagc gcgcccagcg
    12241 ccacgtcgga tgcggacggc cggggcttgt acatgacgct gccgccggcg aagtcgaccc
    12301 gactgaccgt caggccgccc cggtgggtgt cgcccgcccc gaacgcgacg gcgcgcatct
    12361 cccccgcggg tccccccagc agcggccgca gcacttcgcg gtccgcggcg agccgttccg
    12421 cgaatccggc cgtcgccgcc accgacagcc gcgccaccga cgcgatccgc gggccgaggt
    12481 tcgggtatcg gccggtcagc cggtcgagat agccctcctc cccggcctgc tccaggaacg
    12541 cggtccacgt ccgcgtgtcg gatcccgccc ccgcgtcctc ggcgtgacgt ccgccgcccg
    12601 ctgtcatgcg cagcgcgtgc agttcgatca ggaacaggcg ggacagcttc gcgtgcaggg
    12661 acttgagcag ggcggtgtgg ccggcttcca gtaccgtttc ttgttcttcc cggctcaggg
    12721 cgtcaaggga ggccagccgc cgggccagct cttcccgcca aggccgggcg atcgtccgta
    12781 cgggtcgggc gaaccattcc gcctcgtccc gcctccccga ctcccccggc ttccccggcc
    12841 tttccgatcc ttccggcgcc gatccgctca ccgtccaccc tccccattcc gccatgaact
    12901 cgcttcttgc ggtcgttccg agggagcgcg ggcaactgtg cgaccagccc ggacccgtcc
    12961 gcacccggca gcaaccgacc gagccggaaa cccccgcatc cccgacgcgc gcggggcggg
    13021 cggcaaccga ctcggcaggc tgcggcgcgt tcccgggtgc ggacgcgtcg tggcttggcg
    13081 cgcggtttcc cacgctccgg ctttatgaac cgcaccccgc aggggcgctc ccgaagaggc
    13141 gtactccgca ggcgatacgg tcaaaaagcg cgccctggag agggcactca gcggtcaggc
    13201 cctccactaa gggccctgga gtcaccgcag gcgatcagca acaccagctg ccgtgcgacc
    13261 cactcgggct ggaacagaag ccgtagaggg agtcgctcgg gtcggtgagc gcggcctcgg
    13321 cggcggcgcc gccgacgtag aggggcccgg cggggttggt ctggccgtac gcgctctcgg
    13381 cgcccgccag ccaggcatcg agcacggcgg tggtggcaac gctggtctgg ggcatgagag
    13441 acctccggtg gatgtgggga ttggggcgga ttgcccagcc ctgagtatcg ccgggttcga
    13501 acacccgtca gacgtccaat ctggccaaag ccatgtggtg ttcatgcggc ctgccacctc
    13561 ccacgggacg ggtgggacgg tcgcacggcc gagcgccgac cgggcgggcg cagcggacgc
    13621 cgagcctccg actccaagct ccggcctggg ctgcgcgccg acgaggagcc cctgaagagc
    13681 gaggtaaggg ggcctcggcg ctcgtcggtc accgcggacc ggtcggcaac cgaacgaccc
    13741 cgatctcgcg ctccctcacg tcccggtcca gaccggccac ttggccaaca agcgcaccgg
    13801 cggtctccga tgccggcccc catgaagtcg acggccaccg aggactgccc accgccgtat
    13861 ccgcgcaccg gcacatgtcg gaacgtcctg acaaacctgt tgacatcact tggagagcgc
    13921 tccatagtac gtgccactag agcgcgctaa taaagcgctc tagtctccgg tcgcgaacgg
    13981 ccggcggtcc gcacccatga ccgccgccac cccaccgctc cacgttccgc cgtcacacac
    14041 caaccgcggc cgccgagcag ggccgagcgt gtccctcccc gtcaccgaaa gccctcaagc
    14101 ccgcccgccg ggcgtcgacg ccatcccccc gccccgccaa aacccaccct gaccagcaca
    14161 gagaggcgca acggacatgc gcagaaacca ccgagcggcc gccttggccg gtgttgttct
    14221 cacctgcaca ctcatcgcag ccggctgctc cagcagctcg ggcggcaaga agtccgagga
    14281 acgcggcgcg gccgcctccg cgggcaaggc cgacacccca cgcatgaccg tggccatgat
    14341 cacccacgct gccccgggcg acaccttctg ggacctgatc cgcaagggcg cccaagctgc
    14401 cgccgccaag gacaacgtca agctcgtcta ctccagcgac cccaacgcgg gcaaccaggc
    14461 caatctcgtg cagaacgccc tggaccagaa ggtcgacggc atcgcgctca ccgcggccaa
    14521 gcccgacgcc ctgaaggcgg tggcggccaa ggccgcatca gccggcgtac cggtcgtggg
    14581 cttcaactcc ggcttggacg actggaagcg actcgacatg ctcgagtact tcggccagga
    14641 cgagaacatc gccggccagg ccttcggcgg gcgcctgagc cggctcggcg ccaagcacgc
    14701 tctctgcgtc atccaggagc aggggcaggt cgcgctggag gcccgctgcg ccgggctgaa
    14761 gaagggattc accggcaaga cggacaccct gtacgtcaac ggcaccgaca tgccgtccgt
    14821 gaaggcgacg atcaccgcca agctccggca ggactcctcc atcgaccaag tggtcaccct
    14881 cggcgccccg ttcgcactca cggccgtgca gtcggcgcag gacgccggcg gcaaggccaa
    14941 gatcgccacc ttcgacctca acaaggacct ggtgaaggcc gtccagagcg gatcggtcga
    15001 gttcgcggtc gaccagcagc cgtacctcca gggttacctc gccgtcgacg ccctgtggct
    15061 gtacaagacc aacggaaacg tcagcggagg cggcaccgcg ccggtcctca ccggacctgc
    15121 cttcgtcacc aaggagaacg tcgacaccgt cgccgagttc gcgcagaacg gcacgcgata
    15181 gcggcatccg accggcgctg tgggcacagc ggccgcgcct cccttcgccg catcgggcag
    15241 tcctcggcgg cgagggaggc accgtcgcgt atgccaaagc ccatgacgtg cgccgggtca
    15301 ccgcgcacgg cagacgccgc cgccccgtgc ctcgacgccg cctacccctc ggggccgtcc
    15361 gacggaaccg gcccgctcgt accgcgcacc acgagcttgg ggtccagcac cgcctctcga
    15421 ggctccaggc caacgtcctc cagccgttgc acggcgaacc gcaccgcgtg ctcggccatc
    15481 aggaccgcat cctggcgaac ggtcgtcagg ccgatcggca tcaggtggga gagatggctg
    15541 tcgtcgtagc cgatgacgga catgtcgcgt ggaacgtcga cgcctgcccg cgccagcgcc
    15601 atcaacaagc ccatcgcgca acggtcgttg cccgcgagga ccgctgtcgg cagcggatgc
    15661 ccgctgtcgc gctccgccag gagcacgcgg ccggtctcga tgcccgaccg ctcggtgtgg
    15721 tctccgggga tcacccgtat ctccgactcc aagccgtagt agcgcatcgc ggcccggtag
    15781 gcgcgacggc gttcggccga gccggggccc cggccaccgt cgacgtgcac gatgcgccgg
    15841 tggccctgtt cgaccagatg gtccatggcc tgccggatgc ccttcgcctc ggcactgtgc
    15901 acgaagtcga cgcgggcgcg gggaacccgg cggctgaccg agacggtcgc cgtgcgctga
    15961 ccgagttcct ccaggtacgc gggctccgcc tcgggaccga gaaggatcag tgcctcgcaa
    16021 cggtgactga gcagagcctc caccgccttg gcctcactgc ggccctggga gctcgcggag
    16081 aggacgacgt cgtagccgag ccgttcggcc tcggggtaga tgccctcgat caggtccgag
    16141 tggaaggtct ggtggacggt gaacatcacg ccgagcgtgc gactgcggcc gcgggccagg
    16201 agccgggccg cgctgtccaa gcggtagccg atctcgtcgg cgacacgcag cacccgctcg
    16261 cgggtctcct gactcgcacc gggctgattc cggaagatga tcgagaccag cgcacgggaa
    16321 acaccagcct tctcagcgac gtccgccatc gtgggccgct gcttgcccga tgcgtccacc
    16381 tgcgtaccca cccttcgacg gcgcccaccc taagggcagt cgcgaaatct cccagcaaca
    16441 agctattgac atgacatttg gacaggggcc atcgtactcg aactagagcg cgctagtaga
    16501 gcgcgcgaga gaacccaccg taagaccgcc gaaagtcccc cgccccctcc cccaaggaca
    16561 cgccatggca ccggcgccat ccccgctccg caccaccgcg ggcaacctct gcctgggctc
    16621 cgctcccgac tcctggggcg tctggttccc cgaggacgag caccaggtcc cgtacacccg
    16681 cttcctcgac gaactcgcgc aggccggcta cgagtggctg gagctcggac cgtacggcta
    16741 tctccccacc gacccgcagc ggttgaaggc cgaactcgac gcccgtgggc tccaggtctc
    16801 cggcggcacc gccttcggtg cgctgcaccg accgggagcc tgggacgaga tgctcgcgca
    16861 cgtacggcag gtggccgcgc tgaccgccgc cgcgggcgcc caccatctgg tcctgatccc
    16921 gcccatgtac cgggacgaga agaccggcga gttcaccgag ccgcccgagc tgaccgccgt
    16981 gcagtgggcg ggcttcggcc gcgccgccga ccggctcggc cgactcctgc tcgacgagta
    17041 cgacctacgg ctcgtgatcc acccgcacgc cgacagtcac atccagaccc agcccgagat
    17101 cgagcggctg ctgggcgagt ccgacagccg gtacaccaac ctctgcctgg acaccggcca
    17161 tgtggcatac ggcggtggtg acaacctgga cctgatccgc cgcttcggcg agcgcgtcgg
    17221 ctacgtgcac atcaagcaga tggacccggc ggtcctcgcc caagtcgccg cggagaacct
    17281 ctcgttcggc gaggccgtac ggcgcggggt gtgcgtgtcc ccgccggagg gcgtgccgaa
    17341 cccggccgac gtggtggccg aactcgcggg acttgccgcc gagttgttcg tgatcgtcga
    17401 gcaggacctg tatccgtgcg ctcccgatgt gccgctgccc atcgccgtac gcacacgtga
    17461 acacctggac ggctgcggcc tctccggcac ccggcgcccg aagaccaccc ggtaggcggc
    17521 ggccatggac gtcagggacg acacggcaac ggcatccacc actgcgcccc ggatcgtcga
    17581 cgacggcccg gccgcggtac gacgacggct ccgggtcatc agcctcatcg cgaccttcgg
    17641 cgggctcctc ttcggctacg acaccggcgt catcaacggt gccctgccct acatgaccga
    17701 cgacctggga ctgaccccgg tcaccgaggg catggtcacc agctcgctgc tgctgggcgc
    17761 cgcactcggg gccgtggccg gcggcaggct ctcggacgcg cgcggcaggc ggcgcagcat
    17821 cctgacactg gcggtgctgt tcttcgtcgg cgcgctcggc tgcacgctgg ccccgaccac
    17881 cgcggtcatg gtggtcgctc ggttcgtact cggcctcgcg gtcggcggcg cgtcggtgac
    17941 cgtgcccgtc tacctcgcgg agatctcgcc ggcggagcga cgcggcgcac tggtcacccg
    18001 taacgaactc atggtcgtca gcggtcagtt gctcgccttc acctccaacg cggtcatcgc
    18061 cgacgtgggt ggtgagtccg gcggtgtctg gcgctggatg ctcgtgatcg ccacggtccc
    18121 ggccgtcgtg ctctggttcg gcatgctggt catgccggac agcccccgct ggctggcttc
    18181 ccagagccgc ttcgacgagg ccttcgaggt gctcaagcag gtcaggtccg aggcccgggc
    18241 ccgggccgaa ctgagcgagg tgtccgcact cgccgtcaag gacgagcagg agaagctcgg
    18301 cggctggcgc gacatgaagg ccaccccctg ggtgcgccga ctgatgttca tcggcttcgg
    18361 catcgcgatc gtgcagcaga tcaccggcgt caacacgatc atgtactacg gcactcagat
    18421 cctcaccgac gccggcttca ccgcggacag cgccctgacg gcgaacatcg ccaacggcgt
    18481 gatctcggtg ctggccacct tcgtcggcat ctggctcctg ggccgcgtcg accgtcggcc
    18541 catgctgatg agcggtcaga tcggaacaac caccgccctg ctgctgatcg gcgtgttctc
    18601 gctggcgttg ccggaaggca cgggccgggc gttcgccgtg ctggcgatga ccgtcacctt
    18661 cctcgccttc cagcagggcg cgatctcgcc ggtgacctgg ctgatgctgt cggagatctt
    18721 cccgatgcgg atgcgcggct tcgggatggg cgtcgcgacg gtggtgctgt ggctgaccaa
    18781 cttcgcgatc ggcttggtct tcccgtccct ggtcgacggg atcgggatct ccaacacctt
    18841 cttcctcttc gtggcggcgg gcgtcctctc gctcaccttc gtcaagcgct acgtccccga
    18901 gaccaggggc cgcaccctcg aaaccctcga agccgaactc cggacgcgct tctcctgacc
    18961 cctcttccga cttctctcct gactccgctc ctgactcctc tcccgaagga aacgatcatg
    19021 accgtacgtg taggtgtcat cggtgccgga atgatcggcc aggaccacat acgacgactt
    19081 accgaggccg tcaccggcgc acgcgtgagc gcggtgaccg acatagacca ggcccgcgcc
    19141 accgaggtgg ccgcccgcgt cggcgcaggc gcgctgccaa ccggtgccga cctgatcgcc
    19201 tccccagagg tggacgccgt tctcgtcacc tcctggggcc ccacccatgc cgagcacgtc
    19261 ctgaacgccg tcacggccgg taaaccggtg ttctgcgaga agcccctcgc cacgaccgcc
    19321 gaggactgtc tgcgtatcgt cgaggccgag cgcgcccacg gccgccggct cgtccaggtc
    19381 ggtttcatgc gccgcttcga cgtcggctac cgccagatga aggaggtcct cgcctccgga
    19441 tcgatcggcg ccccactgat cgtgcactgc gcccaccgca acccgaccgt gccggagtcg
    19501 tacacctccg tgatggccgc gcaggacacg gccgtgcacg agatcgacgt cctgcgctgg
    19561 ctgctcgacg acgagatcgt ctccgcccag gtgatcaccc cacgcgccac cggcaagcgg
    19621 ttcgcgcacc tcaaggaccc gcagatcatg ctcttcgaga ccgcgaacgg ggtccgcatc
    19681 gacctggagg tcttcgtcaa ctgccagtac ggctacgaca tccggtgcga gaccgtcggc
    19741 gaggagggcc tggtccggct gcccgacccg gccgccgtcg gggtccgcac cgccggacac
    19801 cacgagaccg ccgtaccgca ggactggaag gggcgtttcg ccgacgcctt cgacaccgag
    19861 ttccgcgaat ggatcgcggc cgtcggcacc ggcagcgagc ccaccggccc ctccgcctgg
    19921 gacggctatg ccgccaccgt catcaccgac gccgccgtcc gctccctgga gtccgacggc
    19981 accgtcgtca ccgtggacat gaagccccgc cccgcccttt acggaggcgc cgcatgaaga
    20041 tcgccctcga cccctacatg ttccgcgccc tgccgctcga cgagatggtc cgcacggtcg
    20101 ccgaactcgg ctaccagtac atcgagttgt ccccgcgcga cgacttcatg ccgttcttcc
    20161 tgcatccacg ggcggacgac gcgcgtgtgg ccgacttgaa gaactcactg cgcaggcacg
    20221 gcgtccagct ctcctccgta ctcccgctct acaagtggtc ctcgcccgac gagaccgaac
    20281 ggcaggccgc cgtccgctac tggaggcgga tgatcgagat cacggcagag ctcgaatgcc
    20341 cgttgatgaa ctcggagttc aacgggcgcc ccgaccgggc cgccgagagc gaggccgcct
    20401 tctggcgctc catggaggaa ctgctccccg tcttcgaacg cgagggcatc gccctcaacc
    20461 tggaggcgca cccggacgac ttctgcgagg agaacacgcc ggcggtcgac ctcgttcgcg
    20521 ccgtgaacaa gccctgggtg aactacctct actgcgcccc gcactccttc cacctctcgg
    20581 gagcctcgga cgtcggcgcg gacatcgcgg cgatgatgcg ctacgccggc gacaagctcc
    20641 accatgtgca catcgccgac tccttcaacc acaagggctc ctccggcctg cgctacatcc
    20701 tcaatccgcc cggcaccgcg gcccgcatcc accaacacct cgacatcggc cagggcgagg
    20761 tcgactggga cgccttcttc ggcacactcc gggaactgaa cttcgacggg gtcgccacgg
    20821 cgtgcgtctt cgcctgggag gaacgcgcca gggaatcctc cgcgttcatg ctggaccgca
    20881 tcagcaagga gctctccgcg taacgcgagc gacccaccgt gccccgacgg tcggaggacc
    20941 gccggggcac ggtgggagtg gagggcacct ggatgccgac cgggagaggc cgccgcgatc
    21001 agaccgccgg ggccgggaag gtcgggtact ccacgccgga gacgtgctgg acgacgcgga
    21061 cgacctggca ggagtagccg aactcgttgt cgtaccagag gtagaggatc gcgttgtcgc
    21121 cttcgacctt ggtcgcgccg gcgtcgacga tcgaggcatg acgcgagccg atgaagtcgc
    21181 tcgagaccgc gtcgggggcg ctgatgaagt cgatctggcg cttgagcggc gaggtcagcg
    21241 agacatcgcg gaggtggtcg aggacttcct cgcgcgtggt ctcgcgggcg agttgcaggt
    21301 tgaggatggc gatcgacacg tccggtaccg ggacgcggat ggagctgccg gtgatcttcg
    21361 ccttgaggtc gggcagcgcc ttggcgacgg cggaggcggc accggtctcg gtgatgacca
    21421 tgttgagcgg cgccgaacga ccgcgccggt cggagttgtg gtagttgtcc agcaggttct
    21481 ggtcgttggt gaacgagtgg acggtctcca cgtggccgcg cagaacgccg tactcgtccg
    21541 ccatcgcctt cagcggcggg acgatcgcgt tggtggtgca ggaggcgcag gacatgatct
    21601 gctcgtccgg cttgatcgtg tcgtggttga cgccgtggac gatgttggga acgtcgccct
    21661 tgcccggtgc ggtcaggacg accttggcga tgccggggcg aaggtgctgg gacaggccct
    21721 cgcggtcacg ccacctgccg gtgttgtcga tgaggatggc gtccttgatg ccgtactccg
    21781 tgtagtccac cgacagcggg tcgtcggagt agatcacctt gatctcgttg ccgttggcga
    21841 cgatcttgct gttcgcctcg tcgacggtga tcgtgccccg gaactggccg tgaatggagt
    21901 cgcgccgcag cagcgaggcg cgcttgacga tgtcctggcc ggcacccttg cggacgacga
    21961 cggcgcgcag ccgcaggccg ttgccggagc cggccttctc gatgagcagg cgggcgacga
    22021 ggcggccgat gcggccgaac ccgtagagga cgacgtcgcg cggctcctgg cgctcgatct
    22081 tgttgacgcc cgtggcgccg gccacggcct cggcggtgaa ctccgccacc gacagaccac
    22141 ggtcgtcgca cttgtaggtc gcggcgagca tgccgatgtc gatctgcgac gggccgagat
    22201 cgagcgtggt gagagcctgc aggaacggca gcgtctggat gaccgagagt tcctcgccgg
    22261 cgatctgccg ggcgaaccgg tgggtcttga ggatgctcac cactgacttg ttcaccaggg
    22321 aacggctgtg cagcaggacc gtgacgtccc gctcccggtg cagcttcccg atgatcggga
    22381 tcatcgactc cgcgatctcc tcgcggttgt tccagttggt gaacgagtcg tcattgacag
    22441 tcacagattc atctttcgag ctaggtggcg ctcagatggt agcccgacgc ctttttgatc
    22501 attcgagcgg ggccacctga tcaagaggaa cgcgcagctg agacgctcgt acgccgtcgc
    22561 gccggtggcg cgggtcccgg cgaccggcgt gcgagcgcgc cctcatggac ggtctgcctc
    22621 gcgccttgga tgcccacttc gagggcacga atgcgcccct ttcacgcggt tccgaccgcc
    22681 accggtgact gtttcgcttg acatggggcg cgcgctgccc aactgcccgg accgtcacga
    22741 gattactgtc ctggcgccca cctccccgga acccctcttc gacctccacc gcctccgtga
    22801 acccacgccg cacggcttct gacgcgccgc cggggcgccc cttcgacacg ggttcaggtc
    22861 agacgtcgtc catggccggg ccgtaggagc ccttgcccga ggcgtacggc gtcgacgccc
    22921 tgccttgttc gctgatcttc gtgcgtatcc acccacgccc gctcacgtat cgggaggaca
    22981 tgtgacagtc ccggaaagct ccccagaaag cgccgccggg cccaccgccg acggaccacg
    23041 gtccaccagt ctcagcaccg acgcggcacg tcagctggcc accaccacca agtccgaacc
    23101 tcagatgcag gccatcacct cgcgatggct gctcaagatg ctgccttggg tggacgtcaa
    23161 gggcggcgcc taccgggtga accggcgact ccaactccgc gtcggccggg gccgggtgca
    23221 gttcgagcag aacggcgcgg acgacatcag ggtcattccc gagacactga cagagctgcc
    23281 cgccctgcgc ggctactccg acaccgcggc cctgcaggag atctcctcac ggttcagggt
    23341 gcgtgaggtg cgtacgggcc aggtcctctt cgacgccggg cagcccgtca ccgaggccta
    23401 tctcgtcgtc cacggccggt tcacccgcta caccaccggc aagtacggcg agcaggaagt
    23461 caccggagtc atcacggacg gtgacggcat gggggacgag gccatcggcc aggccgaccc
    23521 gctgtggttc ggctcggtac gggccgagac tccgggcgtg gtgctggcac tcaactggga
    23581 cacgctcatg gcgttcgtgg agcgcacccc gtcgctcgcc gcccagttgg acgccttcgc
    23641 acagcagcag agcaagccca tgaaccgcaa gggcgaggcc gacgtgcccg tgcaggccgg
    23701 acacgtgggc gaaccggtcc tcgccggcgg cttcgtcgac tacgacctcg ccccgcgcga
    23761 atacgagctg tccctgaccc agaccgtcct gcgcgtccac accagggtcg ccgacctcta
    23821 caaccatccg atgaaccaga ccgagcagca actccgcctg accatccagg agatccgcga
    23881 gcgccaggag tgggagctgg tcaacaaccg cgagttcggt ctgctgcaca acgtcgacta
    23941 cggccagcgc gtcagcacct tctccggtcc ccccacgccc gacgatctcg acgaactgct
    24001 gtcgatgcgc cgcaagaccc ggctcttcct ggcccacccg aaggccatag cggccttctt
    24061 ccggcagtgc aaccggcgcg ggctggtgcc cggcacggtg aacctcgacg gccacgaagt
    24121 accggcgtgg cgcggtgttc cgctctttcc ctgcagcaag atcccgatca gtccccagca
    24181 caccagcagc atcatcgcgc tgcgcacggg agagaaggac caaggggtcg tcggcctgca
    24241 ccagacgggc attccggagg agtacgagcc cggtctgaac gtacggttca tgggcatcga
    24301 cagcaccgcg atcatgagct acctggtcac cgcctactac gcgatggcca tcctcgtacc
    24361 cgatgccgcg gggattctgg agaacgtcca ggtcgggcgg accgcggaat gagcacacca
    24421 tcggtttccg gatcgccgac gcgactgccc gggccgcccc gcctcgtccc cgtcacgcaa
    24481 acccggcgga gcggggcgat ccccgggctg cgccaccggc ccgccgcccc cgcggacccg
    24541 gggaaggcag cggaggtcga ccgcaggctg gaggcctggg tccgtcggct cgacgcgttc
    24601 cccaaggcgt ggacggggga cttcgcgggg ttccagttcg gccgggccgt cgtactccag
    24661 catccgggcg cggccgacct cgaacgtctc accacggccg gcaagctgct gctggccgag
    24721 aacctcgtcg acaactgcta ctgcgaggag gacgaggaca gaggcggctc atcgcgcggc
    24781 ctcggcggca ggctgatcag ggcccagtcc gcgctcgacc ccttccactc cactcccgaa
    24841 ctggaggcgc ggtggcggcg cggcgtacag gccgacgggc cgctgcgctc gtaccacggg
    24901 gccctcaagg actacgccgt cttcgccacc cccagccaga ccgaccggct ggtgcacgat
    24961 ctcgcccggc tgcatctggg ctatctcggt gaggccgcct gggccgagat ccggtacgtg
    25021 ccaccggtct gggagtacct gatgatgcgg cagttcaaca acttccgccc ctgcctggcg
    25081 atcgtcgacg ccgtggacgg ctacgagctg cccgaggccc tctacgtccg gcccgagatc
    25141 cagcggatca ccgcactcgc cggcaacgcc accacgatcg tcaacgacct gtactccttc
    25201 accaaggaac tggccaacga tcccagccat ctcaatctgc ctcaggtcat cgccgcgaac
    25261 gaacggtgcg ggctgaaggc cgccttcctg aaggccgtcg agatccacaa ccaggtcatg
    25321 gaggcgttcg aggaggaggc ggcggctctg tccgccacct cgcctctcgt ggagcgctac
    25381 gccgggggcc tggccgcctg ggtgtccggc aaccacgaat ggcacgccac caacacccac
    25441 cgctaccacc tgccgaacta ctggtaacgc cctgccgccc ggcccgtcgt ccaccgcgcc
    25501 acaaggagtc acctttgccc atcaccgatg ccggtaccgc ggcagcaccg atgccgaccc
    25561 aggccacctg ccagtcgacg taccagaccc gcgtcgcgga ctactggaac gccgaggaga
    25621 acccggtcaa cctcgaactc ggaaagatcg acgacctcta ccaccaccac tacggcatcg
    25681 gggacgtcga ccggtcggta ctcgacgagg gccggcacgg gggcggggac ggagacggcg
    25741 cggccatgcg ccgtgaccgg atcaccgccg aactgcaccg tctggaacag gcacaggccg
    25801 acctcctcgc ctcccatctc ggccccctct cccgcgccga ccgcgtcttc gacgccggct
    25861 gcgggcgcgg cggcggaagt gtggtggccc atctgcggta cggatgccac accgacggcg
    25921 tcacgatctc gaggaaacag gccgacttcg ccaatgccca ggcccgcact cggaacatcg
    25981 acgacaaggt ccgctaccac caccggaaca tgctcgacac cggcctgccc tccggcgcgt
    26041 atgcggcttc ctggaacaac gagtccacca tgtacgtgga actcgacctg ctgttcgccg
    26101 agcacgcacg gctgctgcgc cgcggcggac gctacgtgac gatcacgggc tgctacaacg
    26161 acgcctacgg gcgggcctcc cgggaggtgt ctctcatcaa cgcccactac atctgcgaca
    26221 tccacccacg gtcggaatac ttccgcgcca tggcccgcaa ccgcctcgta cccgtccacg
    26281 tccaggacct gaccgccgac accatcccct actgggaact ccgcaagcag gccgaccacc
    26341 tggtcaccgg catcgaggaa acgttcctga gcgcctacga gaacggcagc ttccagtacc
    26401 tgctcatcgc ggctgaccgc gtctgacatc tcccccgcgt tggcgctcct ccggatgcga
    26461 cctatggtga gaagtggtgc agaggcttcc cataaggtgt tcacaacggg gaggacatga
    26521 tcatgtccga agccacacat cccacacatc accgtccgct tcggcggacg cacgacgatg
    26581 ccgcaggcgt cacggccacc atcaaccggg cagcgagcgc cgcgggcgcc gccggtcggg
    26641 ccgcggcgga tgccgtacgg cacccccagg ccgtggtgga ccggttgcgg catctgcctc
    26701 agacgctgcc gctggtgcgg caggcggtga cacccatcct gaccggacga gtgcgtgact
    26761 ggcgtgggga gtacgcctac acgttgggtg agcaggcatt cgtctacggt tttccgtaca
    26821 tctacaacgc caggctgcgc caccagtggg tgacccagcc gcgtgacccg gcgacggtgc
    26881 cgtacgccgc ggtcaaccat ttctggcacg cacaacaact gctggacgcg tcgtaccggg
    26941 acggcggttg tccgaacaac gacaccctgt actcgaccgc gtgggtgaac ctgcgcgacg
    27001 agccggtcat tctctcgcat ccggacatgg gtgatcgcta cttctccttc gagctgatgg
    27061 gcatcacctc cgacaacttc gactacatag gccagcgctc cacgggatcc gaggccggcc
    27121 acttcgcgat cgtcggtccg gactggagcg ggaagcttcc cgatggtgtg cgccgtgtcg
    27181 cgaccgcgcc gagcccgtgg atcctgatcc tcggcaggac gctggtcgac ggcgaggacg
    27241 acgtgccgaa cgtgcagacg ctccaagccc agtaccggct cactccgctc agcttcttcg
    27301 acaggggcgg cggccccgtt gacccggcgc tgctcccggc gagccacgag gtgccggcgc
    27361 cggtggaccc cgcgcaggat cccctcggcc cctggaagac gctcaacgcc atgctggccg
    27421 agaacccgcc accggcgcac cacgcgatcc tgctcaagca gttcgccgag gtcggcatcg
    27481 gtcccggtct cgacgtcgag gcccagcctg aggcggtcag acagaacctc atcagggctg
    27541 cggctgtcgg cacgccgatg ctcaaacagc agatgctcag cggtgagtgg gcacatgtgg
    27601 tgaacggttg gcgttatccg ccaccgcaga taggccgctt cggcgacgac ttcgtcaagc
    27661 gtgccgccga ccagtcgttg gcgggcatca tggccaacga tcccgacgag gcggtctatc
    27721 tgctcaacta cgacgacgcg gacggcaaca agctgtcgtc cggccggtac gcgctgcgct
    27781 tcgacgcggg cgcgatgcca cccgtcgatg ccttctggtc cctgtccgcg tacggcgacg
    27841 acatgaacct gatccccaac ccggccgacc gctactcggt cggggaccgc acgaccggga
    27901 tcgccatgga ccctgacggc ggactgaccc tccatctaca gcccacatca ccgggcgagg
    27961 accgcgagtc caactggctg cccacacccg aaaccggcac ctggttcgtg atcctgcgca
    28021 tgtaccgtcc gcaccgcgag gtcgtggacg cggtatggga atgccctccg ctcacccgcg
    28081 tcgagtgacc cgacgggtcc gtgggccgcg cgtggcggcc cacggacccg tgcgcggggc
    28141 ccctctcagc cgatgtagag ctggtatgtg gcgccgttgc tggtgtcgtt cgccgagatg
    28201 agccggggtt cccaccgcca tccggtgctg ggcttgcggt ggtggaactc gaccgactgc
    28261 ccggctatcc accagtagcc gtccgccacg gtgcaaccct tcggggcgat ctcccagaac
    28321 ctcgagccgc cccagtcgcc gtactggttc tccccgacga agtagaactt caccgtctcg
    28381 gtggacccac tgcagacttt gagctgtacg tacttgttgg cggcgtaggc cgttcccgga
    28441 accgccagac cgccgaagag ggcgcctgcg acgagtgccg ccgtggcgac tttgcgcttg
    28501 agagtgtgca tgggactgtc accattcttg ttcttggacc ggttggactg gacgggaccg
    28561 ggttggactg gatgggggcg gggtgttgag acgggccgga gccgccctgc cggtcgcgag
    28621 gcagggggtg aaggccgatt cagcagtgtg cgccgatttc ggccggggtc atcggccggt
    28681 ccttgaagtt gacgtagccg tagctggggt tgtccttgtt gaagccggac tgctggaagt
    28741 cgtagatgta ccagacgtag tggtcgtagt acttgttctt gaactggatc tcccaccagc
    28801 ccttggcctg ctgcttcgag gttccgcgct caagccaccc gacacttctc ggcgagatgt
    28861 tgatcgtgtt ggactcggtg tcggtgtggg agttctccca gctgtggctg tagctggtct
    28921 ccacggaggc ctcgaagacc aacgagaact tgtaggtcgc cgagacggag acgccgaccg
    28981 tgttgccggc ggtggtcgtg tccgaccagt cgatccggtg ctggttggtg ttgctcccgc
    29041 agttgtacgc ggtgctgccg acctgatgct tcggcccggt gtacccccag tagctctgcg
    29101 ggtggaactt gcagagactt gcccagttgc aggccttcag gagttcggcg ttggtcggac
    29161 tactggccgc gaacgcctgg ggggccacga gcagtgaagc acccatggtc agagctgcga
    29221 gcgtcccggc cgtacgggca atatgcctgg ccgatccgtt cctgcggtgc gcgaatacca
    29281 ttgatcactc catgaggagg gcggatttcg ggggatgtcg cgccgactgc ggtggaacga
    29341 tttcggcgac gcgcgatcgg cgttcatctc gttcatgagc ctcgcagcgc tccatcaggg
    29401 tttgatcaga gccggatcag aggtggctca caaccgcggg aagctcgagg gcgccgtcgt
    29461 gtgcgcggtg ggggtgcggg atcgccgggg tcagtggtgg tggtcgtgac cggccgggcg
    29521 tcgggccagg atgagtgcac gagtggcgac ttcgtcgcag gagacggttc cctgctcgtc
    29581 cagtacgtct tccagcgcgg cgagccaatg gtggtagtag ctccacggcc ggtcctggtc
    29641 gagtgcgttc tcccacgcgg cgatgcgggc gatgagtgcg ccctggaact ggggccaggt
    29701 gaaggcgcct gcctcgtaga gggtgacagc catcccgaag gcgcggctct cccagggttc
    29761 ggagaagacg agttccccgt tggcgcgggg tggggccgcg gtcccgtcga tgtcgagggg
    29821 ggcggtcacg cggctgccac cttcgccacg ccgaccatgg cgtcccgggt gatgagcggg
    29881 acgagttcct cctcggtcag gtgctcggtg ccggcgggcc gctcgggcag gacgagccag
    29941 cgaacctcgc tcgtggagtc ccgcacggtg atctggacgt cgtcgccgag gtcgaggccc
    30001 atctcggaga ggacggtgcg gggttccttg accacgcgtg cacggtagac ggggtccttg
    30061 taccaactcg gcggaaggcc gagcacgggc caggggtagc aggagcacag ggtgcagacg
    30121 acgacgttgt gggtcgtggg agtgttctcg acgacgacga tgtgctcgcc ctgggggccg
    30181 ccgaagccga gttccttgat ggcggaggtg ccgtccgcca ggagccgtcg gcggtactcg
    30241 gggtcggtcc aggccttggc gaccaccttg gcgccgttga gcggacccac gttggtctcg
    30301 tagttggtga tgaacgcatc aacgatcttg gggtcgatca gaccgcgttc ggtgagcagc
    30361 tgttcgagtg cctcggtgcg cagggccgcg gaaggggcct cgccagattc gctggaggtc
    30421 gtcatgaggt ggtctccagg tagttctcga acaggtccac agtgacggcg aaggagtcgg
    30481 cgccctcgcc ccacagttcg tgcgagtcga accgtacgga gtagacgtgt tgggggttct
    30541 cgcccaggaa gtgcgcgtgg gtgtcgggga agacggcagc gggctggatg acctcgacga
    30601 cgccggcgtg tccccggacg tagccgggca ggcgggtgtg cccgggcggc gagatgttct
    30661 tggcgcggac ccgttggccg acggcgaagg cgggggcggc gtcgatggta cgcagcgaac
    30721 caggagcgga ccgccaggcg gcgatcgccg cggtgggcgg gtcggcgtcg ggccgggccg
    30781 attcggggac ggagacggag acggggcgat tttcgacgtg ttcgccgcgc aggtcgcggg
    30841 cccgggcgtt gatctcgccg ggggcgagga tggcgccctc gatgagcatc agttcggcgg
    30901 cgttgagcca gcggccgaag tagccctcat cgaggtaggc ggctcggtcc aggcgttcct
    30961 gcgcgtgccg gaaggcgtcc acattccgac cggacacccg ggtggccagg atcgtcagcg
    31021 cggcggcccg gccctgccag ggctccgcga agaccggttc atcggccctg ggccgacgcg
    31081 cggagcccca tcccgaggtg ccccccatgt cagcgacgcc ttccatgacg cgactcctca
    31141 aatagccgca taacggacca catactcgaa tcttatgcgc ccgcggcctt ctgcgccgcg
    31201 gaccgggatg gatcgggccg ttcaagcagc ccactgccgg cggccgtcct ggccgacggt
    31261 ggcggacgcc ttgcgaatgg tgtgccggga cccgtcggga tcaggtcttg gggccgacgg
    31321 agtcttcgat gcgggcgagc tggtggtcga tgtcggtcaa ccacacctcg agatcgataa
    31381 gtgtgggcag ggccggatgg tgctccggaa gcggtgggcc aggggggctc cggccgggtg
    31441 cggggcgctc gtcggtggtg aagtacgtgg cgatgcggtc ggcgtccgtc gtcagctcgg
    31501 cggccgtccc gcggacccat gcgcgcgcgt cgggcggcac ctcggccagg ggcgcttcga
    31561 agcaaggaag ccgctgggca ccgagtaccg tgtggtacgc cacgatgagc accccgtgcc
    31621 agtcggcctg ggcgccctcc caggcggtgg gtggctcgct gcggaactgc gcgtaggcgg
    31681 cctccgccag acgcagatgc cgcagcgtcg gcaacgtcgc gggcggagac ggagcggccg
    31741 ccgacggggc cagcagcgcc tcgaccgtgg cgggtaccaa cgtcccgcac gagcgcagca
    31801 ggcccgccat ggtgcggtga acctctctcc gtgcccccgc cggccaggcg agcagcccac
    31861 acaggaggcc gatgacactg ccggtgacga catcgacgat gcgggcttcc gacagtcgcc
    31921 agctggtcgg ggtgatctgg gcgaaggcga gggtgaccac cagcgtgaac agcccctgtg
    31981 cgtaggcgat tccgagccgc gggcccagag cgaaggcgat gagcatgcct ggcacgagca
    32041 ggacggcgta ggcgtccagg tgccggccga gggcgatgag cagcgcacct gccgcgacag
    32101 cccccaccag gttgccgatc atggcctggc gcacggcccg ccaggtggcg ccgaccgtgg
    32161 tacgccccag cgtgagtacc gccaggagga cccagaagcc gtgcgcgagg tcgagcgtgc
    32221 cggcgacaag acgggcgatg gcgaggccgc acgcgacccg taccgcgttc tggaaccaca
    32281 ccgagcgatg cgtcgcgttg cccacgacgc gacgcgccca cagctgcgtc gtgggcaggt
    32341 cggcgtacca gaagagttcg cggggccgca gaggtgaggt tctgcgcccg gcggcagaga
    32401 cacccacggc tgtcaccgcg atccacgtcg actcggccag tgtcagctcc gccgcctgtc
    32461 gccgcaggac gtcggtgtcc acgcccggtt cccccggatc ggccgcacgg cggatccgtt
    32521 ccgcctggaa ctgccggatc gccttgtcga gcgcgtcggc cgtcggtggc cgctcaccgg
    32581 cgcgcagggc cgcacccgtg tcctcgcacg tccgcgcgac gcgttcgcgg agcgcggcgg
    32641 acgatggatc cgtgcgcggt gccgcgccag ggggcaggga cgtcgtgctc cgcgacgcca
    32701 actggtccac gacccggcgg accgcggctc ccgcctgtgc cagggcccgg tcccggcgcc
    32761 ccgggccggt cgggcgctca cctggggaaa cctgcgacag ccgcatcccc tcgctgagat
    32821 cacgcagcct cgcgaccgag acccgggccg gatcgaccgc tgccgcggcg gccgtctcca
    32881 gcgcgtcggc aagcacggtc cggtagctcg tggcgggtgg accggacagc acgaacacct
    32941 ggcacaggga gaggagtacg acgcccacgg ccacgcccgt cagtcgggcg cccagcgtct
    33001 gaggggcgta cggcgggaag caggccagga tgtagaggag ttggagaccg ggggcgggac
    33061 ccgccgtacg aggtccggcc accacggtga aactcaacag gaatccgacg atcagcatgc
    33121 cggccacggc ggccgccgtg ctcaccgcga gtgccgtgcc cagcgcgacg aacaccactc
    33181 cgaacggcag ggtccgcaag gtgatccatg cctgctgccg accggtcccg ggaatggtgg
    33241 acagcaggcc gaacgcgatc ggtgtgaaca gtgcgtacag cgccgccacg ggctgctgaa
    33301 gaccgtagag gaacgtgtag aagccgacgc tcgccgagca ggtgacctga atcgaccgtc
    33361 gtaggatcgc ggcaccaccc ggccccggcg tcatgcgtgc tcgccgcccg cgccggtacg
    33421 tgcaccgcga acggcccctg acggcaatgg cggctgtccg cgcatggcga ggttcctctc
    33481 ggcaggcacc gcgtgtcctc gacgaccgcg cctctgccca ttttcgaccc tctgaacggc
    33541 cggcgcacgt ggtggcggcc ctgatcggcg cacgggcacg caccaggcac tgggctccgg
    33601 gccgcgcggc gcccggtggg cggggcacct cacgggcccc gccgaaccgg tccggcagac
    33661 ctcaggcggt caggtcgtca ggcggtcagg tcgtcagcag gcaccctcgt cctgccagac
    33721 gccccagtcg gaggcgacgg gagtctcgtt ctgagtccac cacttggcct tccagttgtg
    33781 gttgttgtac gacacctcgt tgccgacggt gtagaccgcg gtcgagctcc aggccggctt
    33841 gcacccagta ctcgggggcg tgggcgtcgg cgtcggcgtc ggggtgggag tcgaggaggg
    33901 cggtgtgacc ccggcgaact tcaccgagta cttggcgaag tcccaggagt tctgcgccac
    33961 actggagcag gtgcccgagg tccggccgcc gttgtcggcc ggggtgcact gacggtcgcg
    34021 gttgagggac cagaacgtga agcggtccat gttgtggctg gtggcgtagt ccagcacggt
    34081 ctggaagtcg gtctgcgtga agaactcgcc ggtgtcgctg cgcccgttca tcccggagaa
    34141 gccctcgtgg gcgtaggcgg tcgcctggtc ccatccgaag gtggactgca ggatctggtt
    34201 gaagttggtc agcgcgctgg tctgcgacgc cgcgccgttg aagcccccgt cgaacggcat
    34261 gatggagaag ttgttcgggg tgaaaccctg tgacttcgcc tccagcagca tctgctttcc
    34321 gaaccagccg gtcccgtcag cggtgccggc ggtggtgacg gagacgtaga gtccggggtt
    34381 gttctgctgg aggatcttcg cggcgccgat ctcgttcttg atggccgccg tgttctcgta
    34441 ctccggctcc tcgaggtcga agtcgatggc gtgcagaccg tacttggtga tgacctgctg
    34501 gtacgccgcc gccgtggcag ccgcgtccga gcacacctgg ccgagcttgg tgccgccgta
    34561 accgccgatg gagacggaga cgtcgccgcc cttggcacgg atggtgttga cgaccgactg
    34621 cacggcggtg tccgaggaga ccgcggccgt accgccccat gtggggctgc agccgccgcc
    34681 gttgggggcg aggacgaagg cgagctggaa cgccttgagg ccggtggcgt ccatgatggt
    34741 ggccgggtcc ggcgggtcgt tgtcgagcgg catcaggtag ggagccgcgg cgtaccagcg
    34801 gttgccgagt gcggaggtcg cgccggaagc gctgcccgcg accagtgcgg tcgtgcccgc
    34861 tgcggcgagt ccaacggcgg ctgccgcgcc cagacatgcg cgaagacgtc tcactgcgtg
    34921 cctccaggag gtgggggaga gtcgccccag cttcctgcag gtgttgcgtc catgccaata
    34981 gattggccta gaccagataa ctcttggact agaccatacg attgctttac ctctcccccg
    35041 ctacgggagg aacggaacac ggtgagacat cacggtcgac gcacacgaac tgcggagcgc
    35101 gacctccgcc gggtcagccc cgcgcctgcg ccctgacatg tgccgggtac cacttcgtga
    35161 agcggatcgc tgcgaccagc aaggcgatcg ggatgaccca gttgagccag tccgaccccg
    35221 acttcacatg cagcgcgagc agccccagca gggccgtgac caggaacacc ccaccccaca
    35281 tcgccgtcag gatcctgttg gtgcgccgga acaagggtgt gtcccagtac tggcagggca
    35341 ccgactcgcg tgcgtactgc tcggtgaacg gtgtgaaggc gagggaaccg agtgccacga
    35401 cggcgatcac cccgttggcc aacgtctgcg cgtaggtctc cagccacatc aggtcctggc
    35461 ggttcac
//
