LOCUS       NZ_BMUQ01000002        21320 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces mirabilis strain JCM 4551 sequence02, whole genome
            shotgun sequence.
ACCESSION   NZ_BMUQ01000002
VERSION     NZ_BMUQ01000002.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces mirabilis
  ORGANISM  Streptomyces mirabilis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 897824)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 117X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650275.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:52:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,392
            CDSs (total)                      :: 10,311
            Genes (coding)                    :: 9,898
            CDSs (with protein)               :: 9,898
            Genes (RNA)                       :: 81
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 414
            CDSs (without protein)            :: 413
            Pseudo Genes (ambiguous residues) :: 0 of 414
            Pseudo Genes (frameshifted)       :: 172 of 414
            Pseudo Genes (incomplete)         :: 329 of 414
            Pseudo Genes (internal stop)      :: 40 of 414
            Pseudo Genes (multiple problems)  :: 115 of 414
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:21:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 698315
            Orig. end                         :: 719635
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMUQ01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21320
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..21320
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21320
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11320](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11320
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     misc_feature    complement(497..511)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.18"
                     /tool="antismash"
     misc_feature    complement(959..974)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.28"
                     /tool="antismash"
     misc_feature    2214..2228
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     gene            complement(2431..3177)
                     /locus_tag="IE289_RS07360"
                     /old_locus_tag="GCM10010317_015250"
     CDS             complement(2431..3177)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010046680.1"
                     /locus_tag="IE289_RS07360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_015250"
                     /product="hypothetical protein"
                     /protein_id="WP_190168898.1"
                     /transl_table=11
                     /translation="MAEYEGVDALLAAITDEALPEGAGDDPEFMAEHRSAVADVALLRE
                     QLAVIGDALADRAEEAKPVPVRAPRKRSRRPEGAPRNRGRRPLALVVGTLVVATVAAMV
                     VGMGWILAHNGGGAMSTSDSSGAKAADSGSAGDGASLSAPGYLACARLVAEGTVADVEP
                     LPGTTENRITLHVDRYYKPEKGKAEVVLVLDEEVAPRPREGERVLVALQADPATPAGWT
                     TGEKAIADERAWIVKALPESRTLTCP"
     gene            complement(3179..3700)
                     /locus_tag="IE289_RS07365"
                     /old_locus_tag="GCM10010317_015260"
     CDS             complement(3179..3700)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020116428.1"
                     /locus_tag="IE289_RS07365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_015260"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_190168899.1"
                     /transl_table=11
                     /translation="MLRRKARRVQGADDPLDAAQERRVRAVLALGGVPQADLPDGVQQI
                     RLRLLERAAKGDEAPRDVSAWAAVVASNLAMDWHRAKRRQERLGERLASLRQPADARDE
                     DSSVLSLAVAQGLDELPDAQRQVLVLRFYADLSVRGIAEELGVPEGTVKSRLHSAVRAL
                     RARLHEDEVV"
     gene            3995..5011
                     /locus_tag="IE289_RS07370"
                     /old_locus_tag="GCM10010317_015270"
     CDS             3995..5011
                     /EC_number="1.2.1.11"
                     /GO_function="GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA]"
                     /GO_function="GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /GO_process="GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1219: N-acetyl-gamma-glutamyl-phosphate reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019063171.1"
                     /locus_tag="IE289_RS07370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_015270"
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="WP_099922633.1"
                     /transl_table=11
                     /translation="MRVGIVGATGQVGTVMRRILVERKFPVEELRLFASARSAGTVLDG
                     VTVEDAATADYSGLDIVLFSAGGATSKALAEKVAAQGAVVIDNSSAWRKDPQVPLVVSE
                     VNPHAIADRPKGIIANPNCTTMAAMPVLKPLHEEAGLEALVVATYQAVSGSGLAGVAEL
                     HGQVLKVAADADKLTHDGGAVDFPEPGVYKRPIAFNVLPLAGSIVDDGLHETDEEQKLR
                     NESRKILEIPALKVSGTCVRVPVFSGHSLQVNARFARPLSVERATELLAGAPGVTLSEI
                     PNPLEAAGKDASYVGRIRADETAEHGLALFVSNDNLRKGAALNAVQIAELVAAELKG"
     gene            complement(5062..5586)
                     /locus_tag="IE289_RS07375"
                     /old_locus_tag="GCM10010317_015280"
     CDS             complement(5062..5586)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004988066.1"
                     /locus_tag="IE289_RS07375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_015280"
                     /product="DUF1203 domain-containing protein"
                     /protein_id="WP_190168900.1"
                     /transl_table=11
                     /translation="MTTHTTTDMTTYATTYTARPIDPAVLKDLRTADDADRPMVPFADE
                     EGGAPLRCCLRRSEPGERIALVSYAPLRRWAAGTGVDPGAYDEQGPVFVHADDCPGPDL
                     RGHPFPGAHRTVRRYSAEGHILGGRLVENPEGFDEAFAEAFAEAFADPEVALVHVRAVE
                     YGCFLYEVRRA"
     gene            5698..8277
                     /gene="pepN"
                     /locus_tag="IE289_RS07380"
                     /old_locus_tag="GCM10010317_015290"
     CDS             5698..8277
                     /EC_number="3.4.11.2"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="pepN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014672746.1"
                     /locus_tag="IE289_RS07380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_015290"
                     /product="aminopeptidase N"
                     /protein_id="WP_190168901.1"
                     /transl_table=11
                     /translation="MPGTNLTREEAQQRAKLLTVDSYEIDLDLSGAQEGGTYRSVTTVR
                     FDVEESGSETFIDLVAPAVQEVTLNGDPLDPAEVFEDSRIALPGLLEGRNVLRVVADCA
                     YTNTGEGLHRFVDPVDQQAYLYTQFEVPDARRVFASFEQPDLKATFQFTVKAPTGWTVI
                     SNSPTPEPKDDTWVFEPTPRISTYITALIVGPYHSVHSVYEKDGQSVPLGIYCRPSLAE
                     FLDSDAIFEVTRQGFEWFQEKFDYAYPFKKYDQLFVPEFNAGAMENAGAVTIRDQYVFR
                     SKVTDASYEVRAATILHELAHMWFGDLVTMEWWNDLWLNESFATYAEAACQAYAPQSRW
                     PHSWTTFANSMKTWAYRQDQLPSTHPIMAEINDLDDVLVNFDGITYAKGASVLKQLVAY
                     VGMDEFFKGVQAYFKRHAYGNTRLSDLLGALEETSGRDLKTWSEKWLQTAGINILRPEV
                     ETDANGVITSFAIRQEAPALPEGAKGEPTLRPHRIAIGLYNLDDDSGRLVRDQRVELDV
                     DGELTAVPELVGKRRPAVFLLNDDDLSYAKVRLDEDSLAFVTEHLGDFESSLPRALCWA
                     SAWDMTRDGELATRDYLSLVLSGIGKESDIGVVQSLQRQVKLAIELYADPTAREALLTR
                     WTDATLAHLRAAEPGSDHQLAWARAFAATARTPEQLDLLEGLLEDRESIEGLAVDTELR
                     WAFVQRLAAVGRYDEAEIGAEAERDKTAAGERHAETARASRPTEEAKAEAWAAVVESDK
                     LPNAVQEAVIGGFAQTDQRELLAPYTDKYFSVVKDIWDARSHEIAQQIVVGLYPSVQVS
                     EETLAKTDAWLAAAEPTPALRRLISESRSGVERALKAQAADAAAASA"
     gene            complement(8377..9648)
                     /locus_tag="IE289_RS07385"
                     /old_locus_tag="GCM10010317_015300"
     CDS             complement(8377..9648)
                     /GO_function="GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020116434.1"
                     /locus_tag="IE289_RS07385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_015300"
                     /product="M14 family zinc carboxypeptidase"
                     /protein_id="WP_190168902.1"
                     /transl_table=11
                     /translation="MRGTPYPTLGELLRRAHATVAARPGALRLRAVGTSRAGRPLWLLS
                     AGHGPRHILTVAGAHANEPVGGVTSLSLAERFAREPALLQESGCTWNFLLCLDPDGASL
                     AGRWLTGRPGEGLPGEGRAAEASPTLRGYYRRFYRPAFAAQPEFPPVASDPRPVMPESE
                     ALVRLIDELRPVVQFSLHGVEVGGSFLQLTRAVPGAAVAYRRIAADLGIPLEHRPFDGM
                     GWLAESPGVLVLPDSSPTEERDPSGFTSQATWLYAMRHGTVSAVVEAPFWSVAGVSDPR
                     PVDEPRREVAEASEILLGRAKQLEAVVGELGPRSPETPEEIAHFTAARELMDIGPGVVD
                     TWNSAELATTVGNAVSLGVAARRIPLRAAAMMRQALGGAPALDTLVEAWARELASTFDA
                     RWVPVADQTELQIRTMLALARALV"
     gene            10001..11320
                     /locus_tag="IE289_RS07390"
                     /old_locus_tag="GCM10010317_015310"
     CDS             10001..11320
                     /GO_function="GO:0008641 - ubiquitin-like modifier
                     activating enzyme activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387620.1"
                     /locus_tag="IE289_RS07390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_015310"
                     /product="ThiF family adenylyltransferase"
                     /protein_id="WP_229888832.1"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 5.2e-23,
                     bitscore: 76.6, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 2.1e-41, bitscore: 137.4,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVDTLRRPRIKPEHRPYRTIDGNVRIGSVIHGIGAEIEDPQGWV
                     WTLVETMDGTREPSAVVGEVLRAHPELPDLTPEDARQAMADLLDAGFVEDAAAPVPVSE
                     RERLRYSRGVPLLRWMDLGPRTSPWDAQLRLRRARVLLVGVGGTGGYAAQSLVASGVGR
                     LHCVDPDVVELSNLNRQPLFRESDLGRPKVTAALATLRALNSDVTVTGERREIRHPADL
                     AELIRTGAPDVPSEPKQAGTPQAPSEPKQAGTPQAPSEPKQAGAPELPYSSRSSYDLLV
                     LAADRPDDIRRWANRVCLAADLPWVDAGYRGPLVTAGVHVPGRGACWECLRAGEVARRE
                     LRLAPGQDDGVASPHLPWNPATAVTAGLSGGLLAHAALALLTGVPALDPGFRFGMNLML
                     PGDPVLQRFPRRPDCPACGDRPADGATGTGGATGAAGEHA"
     aSDomain        10019..10309
                     /aSDomain="Pantocin_Microcin_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing E1-like protein in a
                     pantocin/microcin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_IE289_RS07390_Pantocin_Microcin_RRE.1
                     "
                     /evalue="1.90E-24"
                     /identifier="RREFam017.1"
                     /label="IE289_RS07390"
                     /locus_tag="IE289_RS07390"
                     /protein_end="103"
                     /protein_start="6"
                     /score="76.6"
                     /tool="antismash"
                     /translation="RRPRIKPEHRPYRTIDGNVRIGSVIHGIGAEIEDPQGWVWTLVET
                     MDGTREPSAVVGEVLRAHPELPDLTPEDARQAMADLLDAGFVEDAAAPVPVS"
     gene            11317..12477
                     /locus_tag="IE289_RS07395"
                     /old_locus_tag="GCM10010317_015320"
     CDS             11317..12477
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020116436.1"
                     /locus_tag="IE289_RS07395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_015320"
                     /product="hypothetical protein"
                     /protein_id="WP_190168903.1"
                     /transl_table=11
                     /translation="MNHVRLHALDSRPDGDEWIVGRLATGRFVALPEVGKQALDLLGQG
                     LSTTEVGERLRETTGDDIDVPDFVEALVDLGFVAEVDGREVASPPPPKPTLARISPRHV
                     RWVLSPALPVLIALLITTTLLIRPPVPLSYHTLLWSPHGSAVIALGAGFGWTLLLLHEC
                     AHLVTARATGVPGRMRLGTRLQFLVMQTDISGIELAPRRHRLTAYLAGIATNLTAASLA
                     ALAAGATHGTPRRILAAVALLALLPLPFQLMVFMRTDVYFVLQDLTRCRDLYGDGVAYT
                     KYAARRALRRTTAPDPSLELPAHERRAVRAYSVVLVVGTTLCLAFLATVTLPADITLFA
                     RAVAHLGPGHSPAVRLDATAVVVALGGVHVLWARTWWRDRRGRRSS"
     gene            complement(12526..13302)
                     /locus_tag="IE289_RS07400"
                     /old_locus_tag="GCM10010317_015330"
     CDS             complement(12526..13302)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018837202.1"
                     /locus_tag="IE289_RS07400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_015330"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_190168904.1"
                     /transl_table=11
                     /translation="MLLTDKTAVIYGAGGSIGGAVARTFAREGAHVHLVGRTAATLDAV
                     AKDIEAEGGRAGTAVVDALDEAAVEAHIASLDAVDISFNLVTRGDVQGASLLDMPVDDF
                     VRPVVTGIRANVVTARAAARRMAERGSGVVLTLNSGSAHGSPMMGGTGPADAAIDTLVR
                     NLAMELGPRGVRAVGLWAAGVPETLTREKLAAVDSAMALDENALQGLLANLAGMRMTRR
                     NPTLPEIAATAAFLASDHAGGITGTFVNVTGGMFPG"
     gene            complement(13391..14749)
                     /locus_tag="IE289_RS07405"
                     /old_locus_tag="GCM10010317_015340"
     CDS             complement(13391..14749)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016435127.1"
                     /locus_tag="IE289_RS07405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_015340"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_190168905.1"
                     /transl_table=11
                     /translation="MVDGVCPGCGKPLAGRTGRKGRSSVYCSAACRQRAYRERRAAPSD
                     TVQGLIEEVGRQVRELVPAPPAVFYSGVSELATSVGRLRRIARTARDTAGPGTADPVTE
                     EPVMGEPGAVDPVTTGPVTEVALAESDFAALVESYRRELRVHCYRMSGSYDDAEDLVQE
                     TFLRAWRARDGFAGRASVRTWLYRIATNACLDFQRRTARRPQWYEPLPGMNHGGAEPPA
                     RITWLQPYPDDDLPSTEEQPDALAVSRETLELVFLAAIQHLPPRQRAVLVLRDVLGLAA
                     AETAAVLDMTVASVNSALQRARPTLRDHLPRRRADWTAEADAREREILARYMAAAERLD
                     LTEVATLLSEDITLTMPPNPFWFVGREALVEFLSVSLDPASPMFLGHWRHLPARANGQL
                     AAGGYVRRPGTTVYRAQVLDVLRVEGDRIVEITSFEPHLFPAFGLPLRLPADR"
     gene            complement(14809..15762)
                     /locus_tag="IE289_RS07410"
                     /old_locus_tag="GCM10010317_015350"
     CDS             complement(14809..15762)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010986797.1"
                     /locus_tag="IE289_RS07410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_015350"
                     /product="EamA family transporter"
                     /protein_id="WP_229888805.1"
                     /transl_table=11
                     /translation="MAANANRPALIALTALAPIAWGSTYAVTTEFLPADRPLFTGVMRA
                     LPAGLLLLASARVLPRGAWWGKAAVLGALNIGAFFPLLFLSAYRLPGGIAAVVGSVGPL
                     FVAGLAALLLGDRPTLRTLLTGVAAALGVSLVVLKAAGALDAVGVLAALAATASMSTGT
                     VLTKRWGRPDGVGPLALTAWQLTAGGLLIVPVALLVEGAPPALDGRAVGGYLYLALANT
                     AVAYWLWFRGIGRLSATQVTFLGPLSPLTAAVIGWAALGQSLTPVQVAGMVLAFGATVF
                     GQVGPRGGRPAPAGGFAGGGRGAGGAAITSRRPRVT"
     gene            15948..16445
                     /locus_tag="IE289_RS07415"
                     /old_locus_tag="GCM10010317_015360"
     CDS             15948..16445
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010986796.1"
                     /locus_tag="IE289_RS07415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_015360"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_190168906.1"
                     /transl_table=11
                     /translation="MKTPQDPVDAIIEQWATARPDLDTAAMEVFGRVFRLARTMGDRME
                     KAYAPYGISRGEFDVLATLRRSDAPYTLSPRQLSATLMLTTGGMTGRLDKLERAGLLGR
                     SPDPHDRRGLQVTLTDKGLRLIDEAVGAGLAVQTEALAHLDEERAGQLAALLRELLIGT
                     GA"
     gene            complement(16484..16885)
                     /locus_tag="IE289_RS07420"
                     /old_locus_tag="GCM10010317_015370"
     CDS             complement(16484..16885)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431463.1"
                     /locus_tag="IE289_RS07420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_015370"
                     /product="hypothetical protein"
                     /protein_id="WP_190168907.1"
                     /transl_table=11
                     /translation="MVPRREAQAHGHLKSFPTQGHDLGLDIAGVVAGAVLGVACGAATR
                     LSRASDGIAFARAGALAALLWIVGMASRAGFEYWATHGGSGSLARFSQDNLITGSAAWT
                     AALLLMALAQVLGRLAVIRVRSSRVATAG"
     gene            complement(16988..17437)
                     /locus_tag="IE289_RS07425"
                     /old_locus_tag="GCM10010317_015380"
     CDS             complement(16988..17437)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025471.5"
                     /locus_tag="IE289_RS07425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_015380"
                     /product="DUF4279 domain-containing protein"
                     /protein_id="WP_190168908.1"
                     /transl_table=11
                     /translation="MSAFRMYLRVVSESLQPEEISARLGTGPDEATAIGSRRRPQSPPR
                     AHATWIRHASAAGGPGRPEDLEPVLLGWGPEFAAALGRLAGSGDADVSLVIVQELTDPE
                     DPRQKGIFLGAALLAWLAQAGASLDIDQYVYYDCDDQRGDGDPVQ"
     gene            complement(18022..19527)
                     /locus_tag="IE289_RS07430"
                     /old_locus_tag="GCM10010317_015390"
     CDS             complement(18022..19527)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136111.1"
                     /locus_tag="IE289_RS07430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_015390"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_190168909.1"
                     /transl_table=11
                     /translation="MNGKTNGKVNGTIASRNVIVVGSGPTGLLLAGDLAAAGVPVTLVE
                     KRPHGISNLSRAFVLHARTLEQLDARGLADELESHGRTVDRIRLFGRLSVALDTLPSRF
                     NHLLVIPQYEVERALERRAVEAGVRFVYETEVTGLRQDAAGVTLEVRGADGAAGELAAA
                     YVVGADGMRSAVREAVGLPFPGKSVIRSVVLADVLLAEEPESILTANAVGDAFAFMVPF
                     GDGYYRVIGWHRGRDVPDSAPLELDEVKEIVRLSLGHDYGMHDARWMSRFHSDERQAPA
                     YRVGRVFLAGDAAHVHTPAGGQGMNTGLQDAANLSWKLALVVNGHADTDLLDTYQAERH
                     PVGKAVLRSSGGIVRLAMAKHPWTLALRSALTTVLNGVGPVRRKAAGQITGIGFAYRAP
                     RGSHALVGTRVPDVALKGGRLYEALRGGRFVLVAPTATVRAYGLDDLKGRKDRLTMESW
                     ASDRRTTLLVRPDGYVAWAAESPDAAAVERALAAALGEDPSSN"
     gene            19641..20234
                     /locus_tag="IE289_RS07435"
                     /old_locus_tag="GCM10010317_015400"
     CDS             19641..20234
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015660350.1"
                     /locus_tag="IE289_RS07435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_015400"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_099922624.1"
                     /transl_table=11
                     /translation="MPDKELPAPAASPAARRSDTTRTAILTAARERFAADGYERATIRS
                     IAKDARIDPSMVMRYYGSKEGLFAAVLDVDLRLPGPDGLDPHEVGRVLVGHFLDLWEEN
                     EVLTVLLRVGVTNPDGAARMQGIFRDQLMPVALRVCPDPEQAPARAALTASQVLGMAMA
                     RYVLRFPPAVALPREEVVAWLAPTVQRYLTAPHP"
     gene            complement(20385..20624)
                     /locus_tag="IE289_RS07440"
                     /old_locus_tag="GCM10010317_015410"
     CDS             complement(20385..20624)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016643174.1"
                     /locus_tag="IE289_RS07440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_015410"
                     /product="hypothetical protein"
                     /protein_id="WP_054231770.1"
                     /transl_table=11
                     /translation="MDKKNALRAGALASGTTLMMLLMSSPALALTRDDGDDPGKGLSVI
                     ETLGLYVVTPIVLFLVIAGLVMVLDKSDKQPKRT"
     misc_feature    20707..20722
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.28"
                     /tool="antismash"
ORIGIN
        1 taccagatcg gtcacttcgg gaccgacaac ccggccaccg acgtcgtcga gagccagccg
       61 ttcgtcgtgc agatccgcaa ggacgtgccg atggacccct acgggggcga ctgggtcggc
      121 aagaaggccg acttcgtcaa catcggtctg atcgcgagcg agcacggcac gcacgtcgcc
      181 ggcatcacct ccgcgaacgg cctgttcggc ggcaagatga acggcgccgc ccccggcgcg
      241 aagatcgtct cgtcgcgcgc ctgcgtgttc ggcccgagct gcaccaacgt cgcgctcacc
      301 gagggcatga tcgacctcgt cgtcaaccac ggcgtcgaca tcgtgaacat gtccatcggc
      361 ggtctgcccg cgctgaacga cggcaacaac gcgcgctccg agctctacac gcgtctcatc
      421 gacacctacg gtgtccagct ggtgatctcc gcgggcaact ccggccccgg cgccaacacc
      481 atcggcgacc ccggcctggc cgacaaggtc atctcggtcg gcgcgtccat ctccaaggac
      541 acctgggccg ccaactacgg ctccgtcgtg gagaagaagt acgcgatgat gccgttctcc
      601 tcgcgcggtc cgcgtgagga cggcggcttc acgccgacgc tgaccgcgcc cggcgccgcg
      661 atcaacacca cgcagacctg gctgccgggc tccccggtcg cccaggccgg ctactccctg
      721 ccggccggct actcgatgct ccagggcacc tcgatggcct ccccgcaggc cgccggcgcg
      781 tccgcgctgc tgctgagcgc cgccaagcag aagggcatcg ccctgacgcc cgccaagctg
      841 cgcacggccc tcacctcgac cgccgaccac atcaagggtg tgcaggcgta cgaggagggc
      901 gcgggcctca tcaacatcgt ggacgcgtgg aagtcgatca aggacgacgt gaccgcccac
      961 gactacaccg tcaaggcccc cgtcgacacc gcgatcgact acgccctgaa gaccccgggc
     1021 ttcggcaccg gcctctacga ccgcgagggc ggcctcaagg tcggcgtgaa gaagtcgtac
     1081 gagatcacca tcacgcgtac gtccggcccg gacaaggcga tccgccacga gctgcacttc
     1141 gagaacaacg ccggtgacac cttccggatc gtcggctccg acgaggtcaa gctcgaactg
     1201 aacaagccgg tcaccgtcaa ggtcgccgcg aaggcctcct cggccggcat caagagcgcg
     1261 atcctcgagg tcgacgaccc gcggaccgag ggcctcgaca agcagatcct gacgacggtc
     1321 gtggtctcca cgccgctcaa gtacagctac tccgcgtcga gttcggtgca gcgcaacagc
     1381 acgcggtcgt acttcctgac cgtgcccgag ggcgcgaagg cgctggaggt cgcgatcggc
     1441 gggctgaagg acctgagcca gacccggttc atctccatcc acccctacgg tgtcccggtc
     1501 gaggacaccg gcacgccgta ctgctacagc aactacccga acaccaacgg ctgcaagccc
     1561 gacgtgcgtt cgtacgcgga cccgcagccc ggtgtctggg aggtcgaggt cgaggcgcgc
     1621 cgtacctcgc cgctgctcga caacccgtac aagctggagg ccaccgtgct cggcgcggcc
     1681 ttcgacccgg ccgtggtgac ggtccccgag gccaaggtcg gcacgccggt caccgcctcc
     1741 tggaaggtga cgaacggttt cgcggcgctc gacggcaccc tgaagggcgg cccgctcggc
     1801 tcctcgaaga cggcccggcc gagcatcgcg ggcggcgcca cccagaccag cacggtcgag
     1861 gtgccggccg gcgccgcgtc gctcgacgtc gccatcggca acgtctcgga cacggccgcc
     1921 gacctggacc tgacggtgta cgactccgca ggcaagcagg tcgcgcagtc cgcggacggc
     1981 gactcggagg aggcggtctc catccccaac cccgccgccg gtacgtacac catcgaggtc
     2041 gtgggctact cggtcccgtc gggctcgacc gcgtacgact accgtgacgt gttcttctcc
     2101 tccgcgctcg gctcggtcaa ggtcgacgag tcggcgccgg tgaagctcgc cacgggcggt
     2161 acggcgacgg tgtccggcga ggtcaccgcg gccgcgccgg cccccgaggg acgcgagttc
     2221 ttcggccagg tccagctggt gaacgcccgc ggcacggccg ccggcctcgg cagcgtgaag
     2281 atcgagaagg tcacgccgta gcaaccggct gacatacgag gggcgggcgt ccggaaacgg
     2341 gcgcccgccc ttcttcacgg gcacgcgcct tcttcacggg cacgcgcctt cttcacgggc
     2401 acgcgccttc ttcacgggca cgcgccttct tcacgggcac gtgagggtac gggactcggg
     2461 cagcgccttc acgatccacg cccgttcgtc ggcgatggcc ttctcccccg tcgtccagcc
     2521 agccggtgtc gccggatcgg cctggagggc gacgagtacc cgctcgccct cgcgcggccg
     2581 gggagccacc tcctcgtcca ggacgaggac gacctcggcc ttccccttct ccggcttgta
     2641 gtagcggtcc acgtggaggg tgatccggtt ctccgtggtg ccggggagcg gctcgacgtc
     2701 ggcgaccgtg ccctccgcga cgagccgggc gcaggccaga tagccggggg cgctgagcga
     2761 ggccccgtcg cccgcgctcc cgctgtcggc cgccttggcc ccgctgctgt ccgacgtgct
     2821 catcgccccg cccccgttgt gcgcgaggat ccagcccatg ccgacgacca tcgcggccac
     2881 ggtggccacg acgagggtgc ccacgacgag ggctagggga cggcgcccgc gatttctggg
     2941 ggcgccttcg gggcggcggc tgcgctttct gggggctcgt accgggaccg gcttcgcttc
     3001 ctccgcacgg tccgccagcg cgtccccgat gaccgccaac tgctcccgca gcagcgccac
     3061 gtcggccacc gccgaccggt gctcggccat gaactccggg tcgtcgccag ccccttcggg
     3121 cagagcctcg tcagtgatcg cggccagcag cgcgtccact ccctcatact cggccacgtc
     3181 acaccacctc gtcctcgtgc aggcgggcgc gcagggcgcg gaccgccgag tgcagcctgc
     3241 tcttgaccgt gccctccggg acgccgagct cctcggcgat cccgcgcacg gacagatcgg
     3301 cgtagaagcg caggacgagg acctggcgct gggcgtcggg cagctcgtcc aaaccctgtg
     3361 ccacggcgag cgagagcacg ctggagtcct cgtcacgggc gtccgcgggc tgccgcagcg
     3421 aggccagccg ctcgccgagc cgctcctggc gccgcttggc ccggtgccag tccatcgcca
     3481 ggttcgaggc gacgaccgcc gcccacgcgg acacgtcacg cggcgcctcg tcccccttcg
     3541 ccgcgcgttc cagcaaccgc aggcggatct gctgcacccc gtccggcagg tccgcctgcg
     3601 gtacgccacc gagcgcgagc accgcccgca cccggcgttc ctgggccgca tccaggggat
     3661 cgtccgcccc ctggacccgg cgtgcctttc tgcgcagcac tccgcccctc ccctcccgcg
     3721 tttcctctac gacgccggtg cgggccaaaa cgttcggccg cacgcgaagg agtcgtacgt
     3781 cacaccgggc cggggccggt gaggacgccc acgccgtacg gcttgcggtt cccggcggcc
     3841 gacggacggt tttctttcgg atgccgcagg aatgccgaag ggcggacgtg tcccattcct
     3901 cgggcggcac gggcaaagga ttggacacgt ggggacgggt cagacgcatg atggaagcgc
     3961 tggaccacgt gaaacgcacg ctaagggagt cgccgtgagg gtcggaatcg tcggagccac
     4021 cggtcaggtc ggcacagtca tgcgcaggat cctcgtcgag cggaagttcc cggtcgagga
     4081 gctgcggctg ttcgcctcgg cgcgttcggc cgggaccgtg ctcgacggtg tgacggtgga
     4141 ggacgcggcg acggcggact actccggcct ggacatcgtg ctgttctccg cgggcggcgc
     4201 gacctccaag gcactggccg agaaggtcgc cgcgcagggc gcagtcgtga tcgacaactc
     4261 ctcggcgtgg cgcaaggacc cgcaggtgcc cctggtggtc tccgaggtga acccgcacgc
     4321 gatcgccgac cgccccaagg gcatcatcgc caacccgaac tgcacgacga tggccgcgat
     4381 gccggtcctg aagccgctgc acgaggaggc ggggctcgag gcgctggtcg tcgcgacgta
     4441 ccaggcggtg tccggttccg gcctcgcggg cgtggccgag ctgcacggcc aggtactgaa
     4501 ggtcgccgcg gacgccgaca agctgaccca tgacggcggc gcggtcgact tccccgagcc
     4561 gggggtctac aagcgcccca tcgccttcaa cgtgctcccg ctcgcggggt cgatcgtcga
     4621 cgacggtctg cacgagacgg acgaggagca gaagctccgc aacgagtccc gcaagatcct
     4681 ggagatcccc gccctcaagg tctccggcac ctgtgtccgc gtcccggtgt tcagcggcca
     4741 ctccctccag gtgaacgccc gcttcgcgcg tccgctgagc gtggagcgcg cgaccgagct
     4801 gctggccggc gccccgggcg tcaccctctc cgagatcccg aacccgctcg aggccgccgg
     4861 caaggacgcg tcctacgtgg gccgcatccg cgccgacgag acggccgagc acggactcgc
     4921 cctcttcgtc tccaacgaca acctccgcaa gggcgccgca ctgaacgcgg tccagatcgc
     4981 ggagctggtg gcggcggagc tcaagggctg acgcccgcac cacgtgcccc ggggcggtca
     5041 ccgcacggtg accgcccttt ctcacgcccg ccgcacctcg tagaggaagc acccgtactc
     5101 cacggcccgt acgtggacga gcgccacctc cgggtcggcg aaggcctccg cgaaggcctc
     5161 cgcgaaggcc tcgtcgaagc cctcggggtt ctcgaccaga cggccgccca ggatgtggcc
     5221 ctcggcggag tagcgacgga ccgtgcggtg agcgcccggg aaggggtggc cgcgcaggtc
     5281 ggggcccggg cagtcgtcgg cgtggacgaa gaccgggccc tgttcgtcgt acgcgcccgg
     5341 atcgacgcct gtcccggcgg cccagcggcg cagcggcgcg taggagacga gggcgatccg
     5401 ctcccccggt tcgctgcgcc gcagacagca gcgcagcggc gcgccgccct cctcgtccgc
     5461 gaagggaacc atcggacggt ccgcatcgtc agctgtgcgg agatccttca ggaccgccgg
     5521 gtcgatggga cgtgccgtgt acgtcgtcgc gtatgtcgtc atgtccgtcg tcgtgtgcgt
     5581 cgtcatggct ccaggctcgc gcccgcgcgt gcctggcacc ggcgggaaac ggacatcgca
     5641 tccgtgcagg tcccatggaa ggatggcgca accgtcacat aacgaggaga tgaccgcgtg
     5701 cctggcacaa acctgacccg cgaagaggcg cagcagcgcg cgaagctgct caccgttgac
     5761 tcgtacgaga tcgatctcga cctctcgggc gcgcaggagg gcggcaccta ccggtccgtt
     5821 accacggtgc gcttcgacgt cgaggagagc ggctcggaga ccttcatcga cctggtggct
     5881 cccgccgttc aggaggtgac cctgaacggg gaccctctcg accccgccga ggtcttcgag
     5941 gactcgcgga tcgcgcttcc ggggctcctg gagggccgca acgtcctgcg tgtcgtggcc
     6001 gactgcgcgt acaccaacac cggtgagggc ctgcaccgct tcgtcgaccc cgtcgaccag
     6061 caggcctacc tctacaccca gttcgaggtc ccggacgcgc gccgggtgtt cgcgagcttc
     6121 gagcagcccg acctgaaggc caccttccag ttcaccgtga aggcgcccac cggctggacc
     6181 gtgatctcca actccccgac gcccgagccc aaggacgaca cctgggtctt cgagccgacg
     6241 ccgcggatct ccacgtacat caccgcgctg atcgtcgggc cgtaccactc cgtgcacagc
     6301 gtgtacgaga aggacggaca gagcgtgccg ctcggcatct actgtcggcc ctcgctcgcc
     6361 gagttcctcg actcggacgc gatcttcgag gtcacccggc agggcttcga atggttccag
     6421 gagaagttcg actacgcgta cccgttcaag aagtacgacc agctcttcgt gccggagttc
     6481 aacgccggcg cgatggagaa cgcgggcgcg gtgacgatcc gcgaccagta cgtgttccgg
     6541 tccaaggtga ccgacgcctc gtacgaggtg cgggccgcca cgatcctgca cgagctggcc
     6601 cacatgtggt tcggcgacct ggtcaccatg gagtggtgga acgacctgtg gctgaacgag
     6661 tcgttcgcca cctacgccga ggcggcctgc caggcctacg ccccccagtc gcgctggccg
     6721 cactcctgga cgaccttcgc caactccatg aagacgtggg cgtaccggca ggaccagctg
     6781 ccctccaccc acccgatcat ggccgagatc aacgacctgg acgacgtcct cgtcaacttc
     6841 gacggcatca cttacgcgaa gggggcgagc gtcctgaagc agctcgtcgc ctacgtcggc
     6901 atggacgagt tcttcaaggg cgtgcaggcg tacttcaagc ggcacgccta cggcaacacg
     6961 cgcctcagcg atctgctggg cgccctggag gagacctccg ggcgcgacct gaagacctgg
     7021 tcggagaagt ggctccagac cgccggcatc aacatcctgc ggccggaggt cgagacggac
     7081 gcgaacgggg tcatcacctc cttcgcgatc cgtcaggagg ctccggcgct cccggagggt
     7141 gccaagggtg agccgaccct ccgcccgcac cgcatcgcga tcggcctcta caacctcgac
     7201 gacgacagcg gcaggctggt gcgcgaccag cgcgtcgagc tggacgtcga cggcgagctg
     7261 acggccgtac cggagctggt cgggaagcgc cgcccggcgg tcttcctgct caacgacgac
     7321 gacctgtcgt acgccaaggt ccgcctcgac gaggactcgc tcgccttcgt caccgagcac
     7381 ctcggcgact tcgagtcgtc cctgccccgc gccctgtgct gggcctcggc ctgggacatg
     7441 acccgcgacg gtgagctcgc cacccgcgac tacctgtccc tggtcctctc gggcatcggc
     7501 aaggagtccg acatcggtgt cgtgcagtcg ctgcagcgcc aggtgaagct ggcgatcgag
     7561 ctgtacgccg acccgacggc ccgcgaggcg ctgctgaccc gctggacgga cgcgacgctc
     7621 gcgcacctgc gcgccgccga gcccggcagc gaccaccagc tcgcctgggc gcgtgccttc
     7681 gcggcgaccg cccgtacgcc ggagcagctg gacctcctgg agggcctgct ggaggaccgg
     7741 gagagcatcg agggcctcgc cgtcgacacc gagctgcgct gggcgttcgt ccagcggctc
     7801 gcggcggtcg ggcgctacga cgaggcggag atcggcgccg aggcggagcg cgacaagacg
     7861 gcggccggtg agcggcacgc ggagacggcc cgggcctcgc gtcccaccga ggaggcgaag
     7921 gcggaggcct gggccgcggt cgtcgagtcc gacaagctcc cgaacgccgt gcaggaagcg
     7981 gtgatcggcg gcttcgcgca gaccgaccag cgcgaactgc tcgccccgta cacggacaag
     8041 tacttctccg tggtgaagga catctgggac gcccgttcgc acgagatcgc ccagcagatc
     8101 gtggtcggtc tctacccgtc cgtccaggtc tccgaggaga ccctcgccaa gacggacgcg
     8161 tggctggccg cggccgagcc caccccggcc ctgcggcgcc tgatctcgga gtcccgctcc
     8221 ggggtcgagc gcgcgctgaa ggcccaggcg gcggacgcgg cggcggcgtc cgcgtagtcg
     8281 gtcgtacgtg agtgggggct cccggcgtcg tgccgggagt cccctttctc gtgagcgcgc
     8341 gtgtgggtgc gtgtgggtgc gcgggggcgc ccggggtcac accagggcgc gggcgagtgc
     8401 gagcatcgtg cggatctgga gctcggtctg gtcggccacg gggacccagc gggcgtcgaa
     8461 ggtgctcgcc agctcacgtg cccaggcctc cacgagggtg tccagcgcgg gggcgccgcc
     8521 cagggcctgc cgcatcatgg ccgcagcgcg cagcgggatg cgccgggcgg cgacgccgag
     8581 cgagacggcg ttgcccacgg tggtggcgag ttcggcggag ttccaggtgt ccacgactcc
     8641 ggggccgatg tccatgagct cgcgggcggc ggtgaagtgg gcgatctcct cgggggtctc
     8701 cggtgacctg ggccccagct cccccaccac cgcctccagt tgtttggccc ggccgagcag
     8761 gatctcgctc gcctccgcga cctcgcgccg gggctcgtcg acgggccgtg gatcgctgac
     8821 gcccgccacg ctccagaagg gcgcctcgac gaccgccgac acggttccgt gccgcatcgc
     8881 gtacagccag gtcgcctgtg aggtgaagcc ggacgggtcc cgttcctcgg tgggactgct
     8941 gtccggcagg acgagcaccc ccgggctctc ggccagccat cccatgccgt cgaacggccg
     9001 gtgttccagg ggaatgccga ggtccgccgc gatccgacgg taggcgaccg ccgcccccgg
     9061 caccgcgcga gtcaactgca gaaaggatcc gcccacttcg acgccgtgga gcgagaactg
     9121 cacgaccggg cgcagttcgt cgatgagccg caccagcgcc tcggactccg gcatcaccgg
     9181 acgcgggtca ctcgcgacgg gcggaaactc gggctgcgcg gcgaaggcgg gccggtagaa
     9241 gcgccggtag taaccccgga gggtcggcga ggcctcggcc gcccgtccct cgccgggcag
     9301 cccctcgccg ggccgcccgg tcagccatcg cccggcgagg ctcgcgccgt cggggtcgag
     9361 gcagagcagg aagttccagg tgcagccgga ctcctggagc agcgcgggct cccgcgcgaa
     9421 cctctcggcc agggagagcg aggtcacccc gcccaccggt tcgttggcgt gcgcgccggc
     9481 gaccgtgagg atgtgccggg ggccgtgtcc ggccgacagc agccacagcg gccggccggc
     9541 acgcgaggtc ccgacggcac gcaaccgcag tgcaccgggt cgtgccgcca ccgtcgcgtg
     9601 agcgcgtcgc agcagctcac cgagggtggg atacggggtt ccccgcatgc cgcgctccgg
     9661 tcaggtgccg ttcgcgttgc tgtccccggt ggtctccttc ttgtccagcg gacggatcac
     9721 gatcttggcg gccatgtggc cccctctctg tgtgggctct gcggtggccg agtgcctgtc
     9781 cggcgaaacg gatcagccgc cgttgcctcc gctgctgtcg cccgtggtct ccttcttgtc
     9841 caacgggcgg atcacaatct tggtgggcac cccaactcct ctcgtcagta gggacgttga
     9901 gcgttgcggg cgcgatcgcc gaccgcgtct tgtcaaggct cgactcgggg gaccagagtg
     9961 tcaaggcatg tacctgtaac gggaaggggt cctggtgacg gtgccggtcg acacgctccg
    10021 caggccccgg atcaagcccg agcaccggcc gtaccgcacg atcgacggca acgtccgcat
    10081 cggcagcgtc atccacggca tcggcgccga gatcgaggac ccacagggct gggtctggac
    10141 gctggtcgag acgatggacg gaacgcgtga gccgtcggcg gtggtcggcg aggtactgag
    10201 ggcgcatccc gaacttcccg acctcacgcc cgaggacgcc cggcaggcga tggcggacct
    10261 gctcgacgcc gggttcgtgg aggacgcggc ggcgcccgtg ccggtgtccg agcgggaacg
    10321 gctgcgctac agccgggggg tgccgctact gcgctggatg gacctcggcc cccggacgag
    10381 tccctgggac gcccagctcc ggctgcgccg ggcccgggtg ctgctggtcg gcgtcggcgg
    10441 cacgggcggg tacgccgcgc agagcctggt cgcctccggg gtcggccgtc tgcactgcgt
    10501 ggacccggac gtggtggagc tgtccaacct caaccgccag cccctcttcc gcgagtccga
    10561 cctcggccgc ccgaaggtga cggccgcgct cgccaccctg cgggcgctga actcggacgt
    10621 gacggtgacc ggggagcgcc gggagatacg acatccggcg gacctggcgg agctgatacg
    10681 gaccggggca cccgacgtcc cgagcgaacc gaaacaggcc gggacgcccc aagccccgag
    10741 cgaaccgaaa caggccggga cgccccaagc cccgagcgaa ccgaaacagg ccggggcacc
    10801 cgaactcccg tactcgtcgc ggagctcgta cgaccttctc gtcctcgcgg ccgaccgtcc
    10861 cgacgacatc cgccgctggg cgaaccgggt ctgtctggcc gcggacctgc cctgggtcga
    10921 cgccggctac cgcggccccc tggtgacggc cggggtccac gtacccggcc ggggtgcctg
    10981 ctgggagtgt ctgcgggccg gtgaggtggc ccgccgcgag ctgcgcctgg cgcccggcca
    11041 ggacgacggg gtcgcctccc cgcacctgcc gtggaacccc gcgaccgcgg tcaccgcggg
    11101 cctgtccggc ggactgctcg cccacgcggc cctggccctg ctgaccggtg tcccggcgct
    11161 cgaccccggc ttccgtttcg ggatgaacct gatgctgccg ggcgacccgg tgctgcagag
    11221 attcccccgg cggcccgact gcccggcgtg cggcgacaga cccgccgacg gggccaccgg
    11281 cacgggcgga gccaccggcg cggccgggga gcacgcgtga accacgtgcg cctgcacgcc
    11341 ctcgactccc gccccgacgg cgacgagtgg atcgtcggcc ggctggcgac aggccggttc
    11401 gtcgcgctgc ccgaggtcgg caagcaggcg ctggacctgc tcgggcaggg gctgagcacc
    11461 accgaggtcg gggaacggct gcgggagacc accggcgacg acatcgacgt acccgatttc
    11521 gtcgaggcgc tggtggacct ggggttcgtc gccgaggtgg acggacggga agtggcctcg
    11581 ccgcccccgc cgaagccgac gctcgcccgg atcagtcccc gccatgtgcg ctgggtgctc
    11641 agcccggccc tgcccgtcct catcgccctg ttgatcacca ccaccctgct gatccgccca
    11701 cccgttcccc tcagctacca caccctcctc tggagcccgc acggcagcgc ggtgatcgcg
    11761 ctcggcgcgg gcttcggctg gacgctcctg ctgctccacg agtgcgcgca cctggtgacc
    11821 gcccgggcga ccggcgtgcc cggccggatg cgcctcggca cgcgcctgca gttcctggtc
    11881 atgcagacgg acatcagcgg catcgaactc gccccgcgcc gccaccggtt gaccgcctac
    11941 ctcgccggga tcgcgaccaa cctcaccgcc gcctccctgg ccgccctcgc cgcgggcgcc
    12001 acgcacggca ccccccgtcg gatcctggcc gccgtcgccc tgctcgcgct gctccccctc
    12061 cccttccagc tcatggtctt catgcgtacg gacgtgtact tcgtgctcca ggacctgacg
    12121 cgctgccgcg atctgtacgg ggacggggtg gcgtacacga agtacgcggc acggcgggcg
    12181 ctgcgccgta ccaccgcccc ggatcccagc ctcgaactcc ccgcccacga acggcgggcg
    12241 gtgcgcgcgt acagcgtggt gctcgtcgtc ggcaccacgc tgtgtctcgc gttcctcgcg
    12301 accgtcaccc tgcccgcgga catcacgctg ttcgcccgcg cggtggcgca cctgggcccc
    12361 ggccactccc ccgccgtgcg cctcgacgcg acggccgtcg tggtcgcgct cggcggggtg
    12421 catgtgctgt gggcccgcac gtggtggcgc gaccgccgcg gccgtcggtc gtcctagccc
    12481 gtcgtcccgg ccggtcgtcc cagccggtcg tgccagccgg tcgtcctagc ccgggaacat
    12541 cccgccggtg acgttgacga aggtgccggt gatgccgccc gcgtgatcgg aggcgaggaa
    12601 ggcggcggtc gccgcgatct cggggagggt ggggttgcgg cgggtcatgc gcattccggc
    12661 caggttcgcg agcaggccct ggagggcgtt ctcgtcgagg gccatggcgc tgtcgaccgc
    12721 ggcgagcttc tcgcgggtca gcgtctcggg cacaccggcc gcccacaggc ccacggcccg
    12781 caccccgcgc ggccccagtt ccatcgccag gttccgtacc agcgtgtcga tcgccgcgtc
    12841 ggccgggccc gttccgccca tcatcggact gccgtgcgcc gaaccgctgt tgagcgtgag
    12901 gaccacgccg gagccccgct cggccatgcg gcgggccgcg gcgcgggcgg tgacgacgtt
    12961 ggcgcggata ccggtgacga ccggacgtac gaagtcgtcg acgggcatgt cgagcagcga
    13021 ggcaccctgc acatcacccc gggtgacgag gttgaaggag atgtcgacgg cgtccagcga
    13081 cgcgatgtgc gcctcgaccg ccgcctcgtc gagcgcgtcg acgaccgccg tcccggcgcg
    13141 gccgccctcc gcctcgatgt ccttggccac cgcgtcgagc gtcgccgccg tacgccccac
    13201 gaggtgcacg tgggcaccct cgcgggcgaa ggtacgggcg acggcgccgc cgatggatcc
    13261 gccggcgccg tagatgaccg cggtcttgtc ggtgagcagc atggtgaacc tccgtgaggt
    13321 gggtcgtaag agcggcccgt acgagtcggc cgtacgagtc ggtcatgcag acgtacgcgc
    13381 cgtctctcac tcatcggtcg gcgggcagcc gcagcggcag tccgaacgcc gggaagagat
    13441 gcggctcgaa ggaggtgatc tccacgatgc gatcgccctc gacacggagg acgtcgagga
    13501 cctgcgcgcg gtagacggtc gtacccgggc gccggacgta ccccccggcc gcgagctgtc
    13561 cgttggcgcg ggcgggcagg tggcgccagt ggccgaggaa catcggggag gcggggtcga
    13621 ggctgacgga caggaactcg acgagcgcct cgcggccgac gaaccagaac gggttcggcg
    13681 gcatggtgag cgtgatgtcc tcgctgagca gggtggcgac ctcggtgagg tcgaggcgtt
    13741 cggcggcggc catgtaacgc gccaggatct cgcgctcgcg ggcgtccgcc tccgcggtcc
    13801 agtcggcgcg gcggcggggc aagtggtcgc gcagggtggg ccgggcccgt tgcagcgcgc
    13861 tgttgaccga ggcgacggtc atgtccagta ccgcggcggt ctccgcggcg gccagcccca
    13921 ggacgtcgcg caggacgagg acggcgcgct ggcggggcgg cagatgctgg atcgcggcga
    13981 ggaagacgag ctccagggtc tcccgggaga cggcgagcgc gtcgggctgc tcttcggtcg
    14041 agggcaggtc gtcgtcgggg tagggctgga gccaggtgat gcgggccgga ggctcggcgc
    14101 cgccgtggtt catcccgggc agcggctcgt accactgtgg gcggcgcgcc gtgcgccgct
    14161 ggaagtccag gcaggcgttg gtggcgatcc ggtacagcca cgtccgtacg ctcgcccgcc
    14221 ccgcgaaccc gtcccgggcc cgccaggccc gcaggaacgt ctcctgcacg aggtcctcgg
    14281 catcgtcgta cgagcccgac atccggtagc agtgcacgcg cagttcgcgc cggtaggact
    14341 cgacgagcgc ggcgaagtcg ctctccgcga gggccacttc cgtaacgggg ccggtcgtga
    14401 cgggatccac cgcgccgggc tcgcccatga cgggctcctc cgtgacgggg tccgccgtac
    14461 cgggacctgc cgtgtcgcgg gccgtccggg cgatgcgccg caaccgtccc acggaggtgg
    14521 ccagctcgct caccccggag tagaagacgg cgggcggcgc cgggaccagc tcacggacct
    14581 gccgcccgac ctcctcgatg agcccctgga cggtgtccga gggcgccgcc cgccgctccc
    14641 ggtacgccct ctgccgacag gcggccgagc agtacacgga actccgcccc ttgcgcccgg
    14701 tccgcccggc cagcggcttc ccgcacccag gacacacacc gtcgaccaca ggaacctcca
    14761 ggaatcgggg aatcggggaa tcgggcgggg gatcggggga tcggggaatt acgtcacgcg
    14821 cggacgacgt gacgttatcg ccgctcctcc agccccgcgg ccgcctcccg caaagcctcc
    14881 ggcgggagcc ggccgcccgc cacgcggccc gacctgaccg aacaccgtcg ccccgaacgc
    14941 cagtaccatc cccgccactt gcaccggcgt cagcgactgc ccgagcgccg cccagccgat
    15001 gacggccgcg gtcagcggcg acagcgggcc gaggaaggtg acctgggtgg cgctgagccg
    15061 gccgatgccc cggaaccaca gccagtacgc caccgctgtg ttcgccagcg cgaggtagag
    15121 gtatccgccg accgcccggc cgtccagcgc gggcggcgcg ccctcgacca ggagggcgac
    15181 cgggacgatc agcagcccgc ccgccgtcaa ctgccaggcg gtgagcgcca acggaccgac
    15241 cccgtccggc cggccccacc gcttggtgag caccgtgccg gtggacatcg acgcggtcgc
    15301 ggcgagcgcc gcgaggaccc ccaccgcgtc cagcgcgccc gccgccttca gcacgacgag
    15361 gctgacaccg agggccgcgg cgacaccggt gaggagcgtc cgcagggtcg ggcggtcacc
    15421 gagcagcagc gccgcgaggc ccgcgacgaa cagcggcccg accgagccga cgaccgccgc
    15481 aatgccgccg ggcagccgat acgcggagag gaacagcagc ggaaagaagg cgccgatgtt
    15541 cagcgcgccc agtaccgccg ccttccccca ccaggcgccg cgcggcagca cccgggccga
    15601 cgcgaggagc agcagcccgg cgggcagggc tcgcatcacc ccggtgaaca gggggcggtc
    15661 ggcggggagg aactccgtgg tgacggcgta ggtgctgccc caggcgatgg gggccagcgc
    15721 ggtcagggct atgagggcgg gacggttcgc gttcgcggcc atggtggcac ccgattccga
    15781 agtaggtcag tgaaaagcag cttagctcta agcgacttct ggtcaagcta ctttgcactg
    15841 aacaactcac cttcaagcaa ctcaccacca agcaactccc tcgccagcta cttcctcgtc
    15901 agctactttc ttgcgggcaa tcgacccctc ggcggatact cgcccccatg aagacgcccc
    15961 aggacccggt cgacgcgatc atcgagcagt gggccaccgc ccggccggac ctcgacaccg
    16021 ccgcgatgga ggtcttcggc cgcgtcttcc ggctcgcccg cacgatgggc gaccggatgg
    16081 agaaggcgta cgcgccctac gggatctcgc gcggggagtt cgacgtgctc gcgaccctgc
    16141 gtcgctcgga cgccccgtac accctctcgc cccggcagct ctcggcgacg ctcatgctca
    16201 ccaccggcgg aatgaccggg cgcctggaca agctggaacg cgcggggctg ctagggcgct
    16261 cccccgaccc gcacgaccgg cgcggactcc aggtgacgct cacggacaag gggctgcggc
    16321 tcatcgacga ggccgtcggc gcggggctcg ccgtccagac ggaggccctg gcccacctcg
    16381 acgaggaacg agccggtcaa ctggccgccc tgttgcgcga gttgctgatc ggcaccggcg
    16441 cctaggggct cggccgggcc gaccgagccc ggccctgagg gcctcagccc gccgtggcga
    16501 cccggctcga cctgacgcgt atcacggcga gccggcccag gacctgagcc agtgccatca
    16561 gcagcagcgc ggcggtccag gcggcggaac cggtgatcag attgtcctgg ctgaaccgcg
    16621 ccaggctccc ggaaccgcca tgagtggccc agtactcgaa tccggcgcgc gaggccatgc
    16681 cgacgatcca caggagcgcg gcgagtgccc cggcgcgggc gaacgcgatc ccgtccgagg
    16741 cgcggctcag ccgggtggcc gcgccgcagg cgacgcccag gaccgcgccg gcgacgacac
    16801 cggcgatgtc gagtccgagg tcgtgccctt gggtcgggaa ggacttgaga tgcccatgag
    16861 cttgcgcttc acgacgcgga accacctcgg ctccaaggtg gagccgaggg tgggtttccg
    16921 cctcaaccca cgggttgaga tcgacccgaa agcccagacg ccgaccagtg gagaacctga
    16981 cgaagcgcta ctggacgggg tcgccgtcgc cccgctggtc gtcgcagtcg tagtacacgt
    17041 actgatcgat gtccagcgac gccccggcct gggccagcca ggccagcagg gccgcgccca
    17101 ggaagatgcc cttctgccgc gggtcctcgg ggtcggtgag ctcctggacg atcaccaggg
    17161 agacgtcggc gtccccggag ccggccagcc gccccagggc cgcggcgaac tccggccccc
    17221 agccgaggag caccggttcg agatcctccg gccgcccggg cccgcccgcg gccgaggcgt
    17281 gccggatcca ggtcgcatgc gcgcgcggcg gcgactgggg gcgcctgcgg ctgccgatcg
    17341 cggtcgcttc gtcgggcccg gtccccagcc gcgcggagat ctcctccggt tgcagggact
    17401 cgctgaccac tctcaggtac atccggaacg cgctcacggc cggtacctgt aattcgtcgg
    17461 aaccaagacc ttcccgtcct tgctcacgag gacgaccctg ccctcgccgt cgcgcatcgc
    17521 gtcgaaccgc gacacgttgt tcttccccac ccagtcggcc ttgaaggcgt gcgggtcctc
    17581 accgacgctc ttcagcgcct tttcgagctg taggcgcccc gcggctcctt ccagtgcgtg
    17641 accttgtcga tccggacccc ggtgccgtcg ggggcgcgga gggtgtcacc ggagttgagg
    17701 tcgcgggcgt cggcccaccg cccccggcgc ggtcgcgagc gtgacgatct tctgttttac
    17761 gtgcaggtac atgtgttcct cagggcgcgg accccaaggc gtcgttcgac ggcgcgggtc
    17821 cgcgcttccc cccgggcggt cgggccaccc tcgtgttgcg tacgtgtcaa acgcgtggtc
    17881 gcaatcacca taaaccgtta ccatcggtca tgttcaactc aacgtcgcac gcggtgagat
    17941 accgcacccg acgcgctgtt gagatgccgg cgcttccacg aagcgccggt caccctcccg
    18001 tcattcccgc tccaggcagg atcagttcga agacggatcc tcgcccagcg ccgccgccaa
    18061 cgcccgctcg acggccgccg cgtcagggga ttcggcggcc caggccacgt atccgtcggg
    18121 ccgcaccagc agggtcgtac gccggtcgct cgcccagctc tccatggtga gacggtcctt
    18181 gcggcccttg aggtcgtcca ggccgtacgc ccggacggtc gccgtcggtg cgacgaggac
    18241 gaaccggccg ccgcgcaggg cctcgtagag gcggccgccc ttcagggcga catcggggac
    18301 ccgggtgccg acgagggcgt gagagccgcg cggggcccgg taggcgaagc cgatgccggt
    18361 gatctggccc gccgccttcc ggcgcacggg accgacgccg ttgaggaccg tggtgagcgc
    18421 ggagcgcagc gccagcgtcc aggggtgctt ggccatcgcg agccggacga tcccgccgct
    18481 gctgcgcagc accgccttgc cgacggggtg gcgctcggcc tggtaggtgt ccaacaggtc
    18541 cgtgtccgcg tggccgttga cgaccagcgc gagcttccag ctgaggttcg ccgcgtcctg
    18601 gaggccggtg ttcatcccct gcccgccggc cggggtgtgg acatgggcgg cgtcaccggc
    18661 gaggaagacc cgcccgaccc ggtacgcggg tgcctggcgc tcgtcgctgt ggaagcggga
    18721 catccagcgg gcgtcgtgca tgccgtagtc atggccgagg gagagccgga cgatctcctt
    18781 gacctcgtcg agttcgagcg gcgcgctgtc ggggacgtcg cggccgcggt gccagccgat
    18841 cacgcggtag tagccgtcgc cgaagggcac catgaaggcg aaggcgtcgc cgacggcgtt
    18901 ggcggtgagg atcgactccg gctcctcggc gagcaggacg tcggcgagga cgacggaccg
    18961 gatgaccgac ttcccgggga acggcagccc caccgcctca cgcaccgcgc tgcgcatccc
    19021 gtccgccccg acgacgtacg cggccgccag ttcccccgcc gccccgtccg cgccccggac
    19081 ttcgagcgtg acgcccgccg cgtcctggcg cagtccggtc acctcggtct cgtacacgaa
    19141 ccgcaccccg gcctcgaccg cccgccgctc caacgcccgc tccacctcgt actgcgggat
    19201 cacgagcagg tggttgaagc gggaggggag cgtgtcgagg gcgacggaga gccggccgaa
    19261 gagacggatg cggtcgacgg tccggccgtg actctccagc tcgtcggcga gaccgcgggc
    19321 gtcgagctgc tccagggtgc gggcgtgcag gacgaaggcg cgggagaggt tgctgatccc
    19381 gtgcgggcgc ttctcgacga gggtcacggg gacaccggcg gcggcgaggt ccccggccag
    19441 caggaggccg gtggggccgg agccgacgac gatcacgttc cgggacgcga tggtgccgtt
    19501 caccttgccg ttcgtcttgc cgttcatggc ggcctcctga tgccaacgcc cgttggtcaa
    19561 cgtttgttgg ccaacgcttg ttcaccaaca tagagagccc actctggact gtcaacaact
    19621 gttggcctac ggttgttggc atgcccgaca aggaactccc cgcacccgcc gcgtcccccg
    19681 cggcccgccg ctcggacacc acccgcaccg ccatcctcac cgccgcgcgc gaacgcttcg
    19741 ccgccgacgg ctacgagcgc gccacgatcc gctcgatcgc caaggacgca cggatcgatc
    19801 cgtcgatggt gatgcggtac tacggctcga aggaaggact gttcgccgcg gtcctcgacg
    19861 tcgacctgcg gctgccgggc ccggacgggc tggacccgca cgaggtgggc cgcgtcctgg
    19921 tgggccactt cctcgacctc tgggaggaga acgaggtcct caccgtgctg ctccgggtcg
    19981 gcgtgaccaa tccggacggc gccgcgcgca tgcagggcat cttccgggac cagctcatgc
    20041 cggtcgcgct gcgcgtgtgc cccgacccgg agcaggcgcc ggcacgggcc gcgctgaccg
    20101 cctcacaggt gctgggcatg gcgatggccc gctacgtcct gcggttcccg cccgccgtcg
    20161 cgctgccccg cgaggaggtc gtggcgtggc tggcaccgac ggtgcagcgg tatctcacgg
    20221 cgccgcatcc gtgacgggcc ccgaaaaggc ttccccgaaa acacgtcgag ggactccgaa
    20281 aacacgtcga gggagtcccc gcacccggtg ggtgcgcgga ctccctcgat cgagaaggat
    20341 ccaggcctcg gcgcgtggcc ggggctccag gaagcgagcc ggaatcaggt ccgcttcggc
    20401 tgcttgtcgg acttgtccag gaccatcacg agacccgcga tgaccaggaa caggacgatc
    20461 ggcgtcacga cgtagaggcc gagcgtttcg atcacgctca ggcccttgcc ggggtcgtca
    20521 ccgtcgtcgc gggtcagcgc gagcgcgggg gacgacatga gcagcatcat cagcgtcgta
    20581 ccggaagcca gggcgccggc gcgcagggcg ttcttcttgt ccacggtgca aacgtagcga
    20641 acacctgaat gagtcgcgcg cccggggtgc cgtacggagg ccgcaccccc gcccggacgc
    20701 cccgctgaca cgcctcggtc acgcccgctc acccgcctcc gtcacgccca cgcgcactct
    20761 caccctcacg cccacgccca cgcgcaccct caccccggtc atcgctccag cggtcatcgc
    20821 tcccgcggtc atcacgtcca ccgcgatgcc cggaccgtcc ccgcagcacg tcgatcagcg
    20881 cgtacagccg gggcgaggcc gccagttcct ccagggtcac cgggcggccg tccgcgtcgg
    20941 cgatgggcag ccgccagttc gggtactggt cccacgtgcc cggcaggttc tgcggtcgcc
    21001 ggtcgccgac cgtgtccggg agccacacgc cgatcatgcg ggccggggtg cgcagcagga
    21061 agcggtgcac ggcctggatc tcggcctcct ccgacaccgc cgaacccgcg tcgcccgccc
    21121 cgtgcagcag cccgagtcgg gcgagcagcg ccagccactc ccccgtgtcc gccgcggccg
    21181 cggtccgctc gtcctccagg gagccggtga gcaggccgag ccggtcgcgg agttcgacgt
    21241 ggtcgccggt gagccgggag gcggtgggcg gcaggtcgtg ggtggtggcg gtggccagac
    21301 agtcggggcg ccagcgctcg
//
