LOCUS       NZ_BMUQ01000001        20912 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces mirabilis strain JCM 4551 sequence01, whole genome
            shotgun sequence.
ACCESSION   NZ_BMUQ01000001
VERSION     NZ_BMUQ01000001.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces mirabilis
  ORGANISM  Streptomyces mirabilis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 935790)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 117X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650275.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:52:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,392
            CDSs (total)                      :: 10,311
            Genes (coding)                    :: 9,898
            CDSs (with protein)               :: 9,898
            Genes (RNA)                       :: 81
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 414
            CDSs (without protein)            :: 413
            Pseudo Genes (ambiguous residues) :: 0 of 414
            Pseudo Genes (frameshifted)       :: 172 of 414
            Pseudo Genes (incomplete)         :: 329 of 414
            Pseudo Genes (internal stop)      :: 40 of 414
            Pseudo Genes (multiple problems)  :: 115 of 414
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:21:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 108131
            Orig. end                         :: 129043
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMUQ01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20912
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20912
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20912
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10912](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10912
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(98..111)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     gene            1155..1664
                     /locus_tag="IE289_RS00530"
                     /old_locus_tag="GCM10010317_001220"
     CDS             1155..1664
                     /EC_number="3.1.1.106"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010038829.1"
                     /locus_tag="IE289_RS00530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_001220"
                     /product="O-acetyl-ADP-ribose deacetylase"
                     /protein_id="WP_190168017.1"
                     /transl_table=11
                     /translation="MTAITLVQGDITRQSADAIVNAANSSLLGGGGVDGAIHRRGGPAI
                     LADCRRLRASHYGKGLPTGRAVATTAGELDARWVIHTVGPVFSREEDRSELLASCYRES
                     LKVADELGARTVAFPAVSAGIYGWPMDDAARIAVETVRATRTAVEEVTFVLFDESAYEA
                     FAVQVR"
     gene            1710..2228
                     /locus_tag="IE289_RS00535"
                     /old_locus_tag="GCM10010317_001230"
     CDS             1710..2228
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018560828.1"
                     /locus_tag="IE289_RS00535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_001230"
                     /product="adenylate kinase"
                     /protein_id="WP_190168018.1"
                     /transl_table=11
                     /translation="MRRILVVGSTGAGKSTLARGLSGRLGLPYHEMDALYFTGAGWAVN
                     EKLSEDVLRITAEPRWVIDSLGYPEVRDLMWDRADTVIWLDYPKRVVLPRVLRRSVRRT
                     VTREPLFGGNRETWTGWLSREHPLWWAWSQHANRRREITRRTGDPRFAPLDTLRFGRPG
                     DTAAWVKSL"
     gene            complement(2239..2616)
                     /locus_tag="IE289_RS00540"
                     /old_locus_tag="GCM10010317_001240"
     CDS             complement(2239..2616)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020556349.1"
                     /locus_tag="IE289_RS00540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_001240"
                     /product="hypothetical protein"
                     /protein_id="WP_190168019.1"
                     /transl_table=11
                     /translation="MNSTKDSDTEAILRGVLDQWKAAVDGHEPEQVAARFTEDAIFQGL
                     HPYSVGRPGVAAYYASQPVGMAAAYRILETRRLTDDLVLGYLSVDFSFTDRPTLNVKLG
                     VLVRRVGETWYISHYQVSRLE"
     gene            complement(2643..3356)
                     /locus_tag="IE289_RS00545"
                     /old_locus_tag="GCM10010317_001250"
     CDS             complement(2643..3356)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431315.1"
                     /locus_tag="IE289_RS00545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_001250"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_075029666.1"
                     /transl_table=11
                     /translation="MSSQNQKVAVVTGASQGLGAGIAEAYRKLGYAVVATSRTIAPADD
                     AGIVTVQGDIADPATAERVIATAVERFGRVDTLVNNAGIFLAKPFHEYTQDDYAAATGV
                     NLTGFFRITQLAVEHMLAQGGGHIVNITTSLVDNADSNVPSVLASLTKGGLQSATKSLA
                     IEYATRGIRANAVSPGTIKTPMHAEETHEALAGLHPVGRMGETSDIVDAVIYLENAPFV
                     TGEILHVDGGMSAGH"
     gene            complement(3569..4489)
                     /locus_tag="IE289_RS00550"
                     /old_locus_tag="GCM10010317_001260"
     CDS             complement(3569..4489)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019062154.1"
                     /locus_tag="IE289_RS00550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_001260"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_190168020.1"
                     /transl_table=11
                     /translation="MTSVELRQLRYFVAVAEELNFGRAAERLLIAGPSLSQQIKTLERD
                     LGVRLFDRDRRSVSLTAAGSALLPHTRALLERADDLQRRAGRLSGSEPVRLGYVNWLPS
                     DLTARTATVAQLHLDAWVAPSHTQAARVAAGGLDLAVCWVRTEDLEERGLRARLIGADR
                     LYAVAGGDDTSDVAARDTTVLLDDDTTSWSSWNVYAEELAQDTGARAVRISNGGITGPA
                     FFDHVRRCSRPVVNSPKGQTTPLPPDLVQRPVTTPEIYWTWSLVWRENEDRPAVLAVVD
                     ALCDGVGDLGIRAPGAWLPDGDPHR"
     gene            4706..5008
                     /locus_tag="IE289_RS00555"
                     /old_locus_tag="GCM10010317_001270"
     CDS             4706..5008
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431321.1"
                     /locus_tag="IE289_RS00555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_001270"
                     /product="muconolactone Delta-isomerase family protein"
                     /protein_id="WP_054230335.1"
                     /transl_table=11
                     /translation="MREFLVEITTTIPEGTTQDEVDRRRAAEAVRARELAATGNLARLW
                     RPVGELRSIGIWCAGDEDELHEKVLGTLPLRPWMSLTVTALESHPNDPGRTDAAR"
     gene            5040..6347
                     /locus_tag="IE289_RS00560"
                     /old_locus_tag="GCM10010317_001280"
     CDS             5040..6347
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018558683.1"
                     /locus_tag="IE289_RS00560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_001280"
                     /product="YbfB/YjiJ family MFS transporter"
                     /protein_id="WP_373306398.1"
                     /transl_table=11
                     /translation="MSVRALRASPAGSAGAPHSPWRHVAQAAAALAAGMGVGRFVYTPI
                     LPLMHAGAGLSAGAGANLATANYIGYLLGALVGILAPAVVRSRALLRVSLVVLTGTLAA
                     MPATHDTAVWFALRLLAGVASALIFVIAVSSLLSHLRAYPAHLPGWAFGGVGAGIALSG
                     LLVLVLRPVADWRAAWWASAALAAVLAVASWNLRPEVPPTTTQAPQAPQAAQATAVTAA
                     TVDDSRGPRTHRWFTALFASYTLEGIGYIIAGTFLVAAIEQSSPGPLGGGAWVLVGLAA
                     VPSSALWARLGRRWSRPDLLLAALVVQAVGIALPALIGGAPAALVSAVLFGATFIGVST
                     LALATGAHLEFPRSVALLTAGYSVGQILGPLAVAPLLHHGYQQALVLAASVVLVAAAAA
                     AVLRIGFPHHMVVVRATAPVRQPAPTESAADAGSHR"
     gene            6367..6981
                     /locus_tag="IE289_RS00565"
                     /old_locus_tag="GCM10010317_001290"
     CDS             6367..6981
                     /GO_function="GO:0070273 - phosphatidylinositol-4-phosphate
                     binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020135399.1"
                     /locus_tag="IE289_RS00565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_001290"
                     /product="GPP34 family phosphoprotein"
                     /protein_id="WP_190168021.1"
                     /transl_table=11
                     /translation="MTTPRDLLMIAMDVPSSRPVEQGDLSLALAGAELVDLIEAQAITL
                     EDDRIVPGAQWTMGDRLLDGAVASLVRQRPYESVDDWLWRRGRGLSAAYRADLEAEGRL
                     ARPRHRWIPFGGGRTEAADSPDRSHADERWTSGEPILTVLAAAVGIHDESTEEAAGLVD
                     DSVLAVLAAVNGAVTELEAVRQRRSIEDAAFDNIWRGGDGT"
     misc_feature    complement(7025..7040)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.38"
                     /tool="antismash"
     gene            7124..8140
                     /locus_tag="IE289_RS00570"
                     /old_locus_tag="GCM10010317_001310"
     CDS             7124..8140
                     /NRPS_PKS="Domain: Abhydrolase_1 (65-312). E-value:
                     2.2e-23. Score: 75.0. Matches aSDomain:
                     nrpspksdomains_IE289_RS00570_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125949.1"
                     /locus_tag="IE289_RS00570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_001310"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_190168481.1"
                     /sec_met_domain="PF00561 (E-value: 3.1e-20, bitscore: 68.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 6.3e-14, bitscore:
                     48.8, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFSRILTIGTAGASLPTLPAISASASASLSADASGPGIHTSFGPL
                     KQIHAGELNMGYAEAGPAHGPAVVLLHGWPYDIHSYVDVAPRLAAAGYRVIVPYLRGHG
                     TTRFRSDKTFRNAQQSVIALDIIALMDALKIEKAILAGFDWGARTADIIAVLWPERCKA
                     LVSVSGYLITNRETQKAPLPPKVEWAWWYQYYFATERGRLGLAQYKHDFAKLIWKNVSP
                     TWHFNDATFDRTATAFDNPDWVPIVIHNYRWRLSLAKGDPRFDRLEKRLAQSPAISQPT
                     ITLDGELDPFTPPGNGASYRSHFTGAYDHRTLKGIGHNVPQEAPEAFAAAVVDVNAL"
     aSDomain        7319..8059
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS00570_Abhydrolase_1.1"
                     /evalue="2.20E-23"
                     /label="IE289_RS00570_Abhydrolase_1.1"
                     /locus_tag="IE289_RS00570"
                     /protein_end="312"
                     /protein_start="65"
                     /score="75.0"
                     /tool="antismash"
                     /translation="PAVVLLHGWPYDIHSYVDVAPRLAAAGYRVIVPYLRGHGTTRFRS
                     DKTFRNAQQSVIALDIIALMDALKIEKAILAGFDWGARTADIIAVLWPERCKALVSVSG
                     YLITNRETQKAPLPPKVEWAWWYQYYFATERGRLGLAQYKHDFAKLIWKNVSPTWHFND
                     ATFDRTATAFDNPDWVPIVIHNYRWRLSLAKGDPRFDRLEKRLAQSPAISQPTITLDGE
                     LDPFTPPGNGASYRSHFTGAYDHRT"
     gene            complement(8178..8798)
                     /locus_tag="IE289_RS00575"
                     /old_locus_tag="GCM10010317_001320"
     CDS             complement(8178..8798)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014059202.1"
                     /locus_tag="IE289_RS00575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_001320"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_099919847.1"
                     /transl_table=11
                     /translation="MGRTSDAREKILSAAQSLIELRGYSALGVAEICKAAGVPKGSFYY
                     FFESKEALALAVLDEHWDAQKSAWARVLNSDEEPLRRLYRLFEETEAGQRAGQQSCGTV
                     SGCLFGNLSLEMSNHTEPIRTRLQEIFDAQVEMVESVITEAREREEVTTPDSREAARAV
                     VAQLEGQVLFAKLYNNTRRLSPLWANCLALLGARAPQEAVAGA"
     misc_feature    8761..8776
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.35"
                     /tool="antismash"
     gene            10001..10912
                     /locus_tag="IE289_RS00580"
                     /old_locus_tag="GCM10010317_001330"
     CDS             10001..10912
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007268955.1"
                     /locus_tag="IE289_RS00580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_001330"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_229888687.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2e-49, bitscore:
                     163.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLDAVHRYAMVPPGKLLRPSLVLHAALTVGGELGAVLPAAVGIE
                     GAHVGSLLHDDIIDRDTQRRGRAAVHTEFGPAQAVVAGNALFFSWFAALSECRRLGVPA
                     DRVERAMAVQAEAGVAICRGAFDELAMRGDLELGVGAYVAMARAKTAVLLAAACRVGAV
                     LGGGDAPTTELLGDFGDHLGICFQIRDDVLPYDPIAARAMGKPSDSDVRNRRPTLPVLI
                     AHRRADPKSRAALRHALLDETEPELALCRIRAVLERTGALDTAHAMADDYARRARELLT
                     RLPATAHVAHVRALALLTRPAH"
     gene            11123..11974
                     /locus_tag="IE289_RS00585"
                     /old_locus_tag="GCM10010317_001340"
     CDS             11123..11974
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607053.1"
                     /locus_tag="IE289_RS00585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_001340"
                     /product="hypothetical protein"
                     /protein_id="WP_229888688.1"
                     /transl_table=11
                     /translation="MDKTERVADPQVADPGASVMKKLPEVTLAFWIMKIAATTLGETAG
                     DLFAQTLKLGYFLTTILLFLIFVVTLVVQLRSRRYNPFFYWTVILSTSMAGTTMSDFMN
                     RDASAKYLSGGATSLGWGPQGLGLGYPAGAAILISLLVVIFTVWKFTGMTFVIRDIVTF
                     RAEALFWSAILVSNTLGTSMGDFLSDSSGLGYAGGALLVTGLLAVLVALMGVPAVPNVL
                     LFWIAFVLTRPLGATAGDFLTKPTAKGGLDLGTAGSSAVLFAVLVGLMGYAHLRERRTL
                     AT"
     gene            complement(12020..12916)
                     /locus_tag="IE289_RS00590"
                     /old_locus_tag="GCM10010317_001350"
     CDS             complement(12020..12916)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676740.1"
                     /locus_tag="IE289_RS00590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_001350"
                     /product="M56 family metallopeptidase"
                     /protein_id="WP_190168022.1"
                     /transl_table=11
                     /translation="MRIDVYIPLVLPLLLTAIAPQVGLKVSPALAARVLTIAAVLAATA
                     STWALLLLAATLVNEAPHVATEAGEDGRRLPEPVPAAIAVVAIMLLWLIGFRLVRALRA
                     HYATHRFLERLCEGHPPDSELIVAASSTPRAFAIPGTPGRILVTAAMLGALEPAERRVL
                     LAHERAHLTHRHSVLSTAVTLAAAANPALAPVRTTVAFLVERWADEEAARRVGDRRTTA
                     RALARAALVAQRARPGCALSFSEHAVTRRIAALQTAPPPNLWSIGVAVLALGALPAFGA
                     LDATGDLLRMLGESLPG"
     gene            complement(12913..13296)
                     /locus_tag="IE289_RS00595"
                     /old_locus_tag="GCM10010317_001360"
     CDS             complement(12913..13296)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019067883.1"
                     /locus_tag="IE289_RS00595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_001360"
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="WP_075029673.1"
                     /transl_table=11
                     /translation="MARTGPHGRAERRSAGELESEVLAALWATEEALTPADIQGEIGGN
                     LAYNTVHTILKRLYDKGLVLRDVDGRRGAYRPAKNAAELTAEAMHEALDRGPDPIAALQ
                     QFVTGLSPQEEEALRDLLGGSGM"
     gene            13495..15000
                     /locus_tag="IE289_RS00600"
                     /old_locus_tag="GCM10010317_001370"
     CDS             13495..15000
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019067921.1"
                     /locus_tag="IE289_RS00600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_001370"
                     /product="hypothetical protein"
                     /protein_id="WP_190168483.1"
                     /transl_table=11
                     /translation="MAKTVNLPLIGAHRHSPPSTGRIFGRPHGQQWLALVAGAFTLAQL
                     ILVRPGMGLGWDETVYVSQVGSHAPAAFFSAPRARGVSLLVAPIASWSSSTALLRVYLA
                     VLSGLGLFVALRVWRGLFPVRVLAAAGALFATLWVTLFYGPQAMPNYWVAIGALACVGC
                     FLRAQADRFDRAALWGVGLSAALMAWMRPTDAVYVTLPLLFLVVCVRRWWRPRLLVALV
                     AGLVAGAGEWVVEAYVSYGGLAQRLSDGSRIQGGLGWNIAFGDQLRSLGGRVLCRPCTG
                     AMPAPPVMLWWFALPVVAVLGAVIAVKARRGVNSLLLLACAAVVGFPYLFMIGYAAPRF
                     LLPVYILLAIPAADALIHLATAPGGGRRPVAATLVALGLAGHLAVQFAVLEHTVHGTTV
                     SHQDWADTATQLHRLGVKPPCMLTGYEDVPIAFYTGCSSVDTGGHNANTTADAIVRAGQ
                     RIPVGVLTTPGEKPPAYARTWEAHRVGHLTVYVAPAVQAGGAT"
     gene            14997..15935
                     /locus_tag="IE289_RS00605"
                     /old_locus_tag="GCM10010317_001380"
     CDS             14997..15935
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019983554.1"
                     /locus_tag="IE289_RS00605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_001380"
                     /product="lysylphosphatidylglycerol synthase
                     domain-containing protein"
                     /protein_id="WP_190168023.1"
                     /transl_table=11
                     /translation="MTLLPPGAPATAASRRVSLHAAVTLAVVVGAVCLGRRHWPVIATG
                     AGRLAVADRGWLLVAAVATVGTWVCSALAQQGAVTRPLPAGQLVAVQFAASAANHVLPA
                     GLGAGAVNLRFLTRCGLPVVRSATALGVKATAGAVSRGFLIAVLALACPGLLRLPHIPA
                     TAVAIALAVVVTAAVLLRGPLRRALRAVLADVRAVHEVPARAAALWGGSLAFAALHATV
                     VVAVAQALELPLPPAQVALAYLAASSAAVLLPTPGGIGSLDAALAVALTLAGVPGSAAA
                     SVVLGYRLLTVWLPLIPGLLSLAVLARRKVL"
     gene            complement(16006..>16146)
                     /locus_tag="IE289_RS00610"
                     /pseudo=""
     CDS             complement(16006..>16146)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010359976.1"
                     /locus_tag="IE289_RS00610"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="NWFGSTKTLDVTMAGLRRRLTDTASRPSRTPRISTLRGHGYRLEP
                     P"
     gene            16109..16741
                     /locus_tag="IE289_RS00615"
                     /old_locus_tag="GCM10010317_001390"
     CDS             16109..16741
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014567.5"
                     /locus_tag="IE289_RS00615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_001390"
                     /product="ATP-binding protein"
                     /protein_id="WP_229888756.1"
                     /transl_table=11
                     /translation="MVTSSVFVEPNQLQLTLEAGLAQDDARLRPALEEALDATRRLHDT
                     VEEVLRLAGSPGPPGAVVRDRSVVHLLAETDARWHGLFAQDGRRLDCGVQDAPADVLVP
                     GGPVAEILGVLLDNARTHGRGSVRVTVRDLDDALAFDVADEGTVTAEPEGLFARGRTGG
                     GNGGTGIGLALARDLAVSLGGRLFLSGGDPTTFTLLVPVAPVAPATR"
     gene            16781..17608
                     /locus_tag="IE289_RS00620"
                     /old_locus_tag="GCM10010317_001400"
     CDS             16781..17608
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004939882.1"
                     /locus_tag="IE289_RS00620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_001400"
                     /product="hypothetical protein"
                     /protein_id="WP_190168024.1"
                     /transl_table=11
                     /translation="MTETSETPGAYVRSGAAPGHRLRWNKVPEVTAYFWIIKVLCTTVG
                     ETAADFLNSNLGMGLTGVSLLMSALLIAVLVVQFRTKAYRPGVYWFAVALISVVGTLIS
                     DNLTDNLGVSLTTCTTVFAVALAVVFAIWYRREGTLSIHSIDTVSREAYYWLAVLFTFA
                     LGTSAGDLVAEKMALGYWVSAILFGLAIAAVAVAHFALGLNAVLSFWIAYILTRPLGAS
                     MGDYLSQPTGDGGLGLGTTVTSVLFLAVILALVVYLSMTRKDVTASERELSLQ"
     gene            complement(17646..19010)
                     /locus_tag="IE289_RS00625"
                     /old_locus_tag="GCM10010317_001410"
     CDS             complement(17646..19010)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010359989.1"
                     /locus_tag="IE289_RS00625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_001410"
                     /product="sensor histidine kinase KdpD"
                     /protein_id="WP_190168025.1"
                     /transl_table=11
                     /translation="MRAFASRWWPRTLRGRLSLVALTTATILMVILTVAFNTVVRRHLQ
                     HQADDELRTRAAAVAATVVTDGSRVRVLETPGEELLDTNVWIYSGGRLLEKPSSATSTS
                     PLTRAAGRLVARGARHCVTVHSHGEVRLCSRPVPGGKGAAAVVTALDLSPYRGSADTML
                     FASLALDAAMLACTYALTRLAVGRALRPVRSMTEHATQWSAIASQERFGAVTRPTELAQ
                     LGGSLDALLDRIRALLRHEQQLTRELSHELRNPLARIIAELDWWGARPRSDADTKATHA
                     AIADAAQSMRTICDTLLDEARDSAATAPGTADVLPVLHRLVDRLGPTKVGVEVVVTACD
                     ARLSAGVPDALLERIVSPLLDNALRHARTRVEILARARPGGVRVEVGDDGPGVPASFAA
                     QLFQPGRRADPEDGHGGAGLGLPLARRLARSAGGEVDHDARRTSGATFVVTLPAG"
     gene            complement(19007..19669)
                     /locus_tag="IE289_RS00630"
                     /old_locus_tag="GCM10010317_001420"
     CDS             complement(19007..19669)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981564.1"
                     /locus_tag="IE289_RS00630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_001420"
                     /product="response regulator transcription factor"
                     /protein_id="WP_190168026.1"
                     /transl_table=11
                     /translation="MRHTILVVEDDHALRDVLLRGLREEGFDTVPAPDGATALRLAGDD
                     VDAAVLDVGLPDADGRDVCQAIRANGFLSPVIFLTAHHHLTDRLAGFSAGGDDYLPKPF
                     HLTELAARLRAALKRSGPLPATTAGDLVLDPVGHSLTVDGTRVGLTPTEFRLLAALMAG
                     SGDIVRRRELIRAGWPEGAQVSDNTLDQYLTRLRRKLRDGGSALAITTARGIGHRLS"
     gene            complement(19785..20393)
                     /locus_tag="IE289_RS00635"
                     /old_locus_tag="GCM10010317_001430"
     CDS             complement(19785..20393)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006378636.1"
                     /locus_tag="IE289_RS00635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_001430"
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_190168027.1"
                     /transl_table=11
                     /translation="MILAFNGSSIDGSTYTYVVNLAHDSPSWLDSLVSAWSTYGLALFA
                     VLMLVGWWQARRSSAQAAMVALAVPVIVVVAFGVNSLFKMVVREDRPCQSLHVKTLEAC
                     PAPGDWSFPSNHTVIAAAAAVALLYVSRRLGTIALLGACLMAVSRVWVGAHYPHDVVAG
                     VLVGTLIAMLLTTLLRRLSDPLASRLTDSRLLRPLLVSA"
     misc_feature    complement(20378..20392)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.34"
                     /tool="antismash"
     misc_feature    20464..20484
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 21.91"
                     /tool="antismash"
ORIGIN
        1 ctgggactgg acggccgacg ccaaccagcg ggcggccctg gtcaaggcga cccaacgcgg
       61 cgccgtcagc gagctgttcg ccaactcgcc gatgtggtgg atgtgcctca accacaaccc
      121 gtccggcgcg tccggcggcg gcaacaacct ccagtcctgg aactaccgtc agcacgcctc
      181 ccacctcgcc gcggtggcgc tctacgcgaa gaacaactgg ggtgtgagct tcagctccgt
      241 cgacgcgttc aacgagccct cctccagctg gtggacggcg acgggcaccc aggagggctg
      301 ccacatggac gccaccgtcc aggcggccgt cctcgcgtac ctgcgcagcg aactcgacaa
      361 gcgcggtctg accggcaccc tggtctccgc gtccgacgag acgagctacg acctggcccg
      421 cacgacctgg aactccttca gctcgaccac gaaagcccag gtcaaccggg tcaacgtgca
      481 cgggtaccag ggctccggcg gtcgccgtga cctcctctac accgacgtcg tcaccacggc
      541 gggcaagcgg ctgtggaact ccgagacggg cgactccgac gccaccggcc tcaccctggc
      601 gagcaacctc tgtctggact tccgctggct gcacccgacc gcgtgggtgt actggcaggt
      661 gatggacccc agcaccggct gggcgatgat cgcctacgac cagagcaccc tccagccgac
      721 gaccgtccag accaagtact acgtgatggc ccagttcagc cggcacatcc gccccggcat
      781 gaccatcatc gacaccggtg tcggatacgc ggcggcagcg tacgacgcga gcgcgaagcg
      841 tctggtcatc gtggccgtca actccggcgc cgcgcagaac ctcaccttcg acctgtccaa
      901 gttcagccag gtcaccgggg gcagcggcgg actcgtacga cgctggaaca ccgtcacctc
      961 cggcagcggc gacctctaca ccgcccactc ggacacctat ctgagcggca agacgctgac
     1021 ggcggccttc tccgccgcgt ccgtgcagac cttcgagatc gacggagtgg tcgtctgaca
     1081 gtcggttgtc gcgtggcggc cggagcgcga tgcggcgagg atcgaagacc gcatacgagg
     1141 aggccgaggc cgtcatgacc gccatcaccc tggtccaggg agacatcacc cgtcagagcg
     1201 ccgacgcgat cgtcaacgcg gcgaactcgt cgctgctcgg cgggggaggc gtggacgggg
     1261 ccatccaccg acgtggcggc cccgccatcc tcgccgactg ccgcaggctc cgcgcctcgc
     1321 actacggcaa ggggctgccc acgggccggg cggtcgccac caccgcgggc gagctggacg
     1381 cgcggtgggt gatccacacg gtcggcccgg tcttcagtcg tgaggaggac cgctcggaac
     1441 tcctcgcctc ctgctaccgg gagtcgctga aggtggccga cgaactcggc gcccgcacgg
     1501 tcgccttccc ggctgtctcc gccggcatct acgggtggcc gatggacgac gccgcccgga
     1561 tcgcggtgga gacggtacgg gccacgcgga cggccgtcga ggaggtcacg ttcgtcctct
     1621 tcgacgagtc ggcgtacgag gcgttcgccg tgcaggtccg ctgactcccc ctttctcgcg
     1681 gacgggtgcg gctcgcttag ggtgcgggga tgcggcggat cttggtggtg ggcagtaccg
     1741 gtgcgggtaa gtccacgctc gcccggggcc tgagcggtcg cctcggcctg ccctaccacg
     1801 agatggacgc gctgtacttc accggcgccg ggtgggccgt gaacgagaag ctgagcgagg
     1861 acgtactgcg gatcaccgcc gaaccccgct gggtcatcga ctccctcggc tatccggagg
     1921 tccgtgacct gatgtgggac cgggccgaca cggtgatatg gctggactat cccaaacggg
     1981 tcgtcctgcc ccgcgtcctg cgccgttccg tccgccgcac cgtcacacgc gagccgttgt
     2041 tcggtggcaa cagggagacc tggaccggct ggctgagccg ggaacatccc ctctggtggg
     2101 cctggtccca gcacgcgaac cggcgccgcg agatcacccg ccgcaccggc gacccgcgct
     2161 tcgctcccct tgacaccctt cgcttcggcc gccccggcga caccgcggcc tgggtgaagt
     2221 ccctgtaagg gggccggact actcgagccg tgacacctgg tagtggctga tgtaccaggt
     2281 ctcccccacg cgtcgcacca gtacgccgag tttgacgttg agggtggggc ggtcggtgaa
     2341 ggagaagtcg acgctcagat aaccgagtac gaggtcgtcg gtgaggcgtc tggtctcgag
     2401 aatccggtac gcggcggcca tgccgacggg ctgggaggcg tagtaggccg cgacgcccgg
     2461 ccttccgaca ctgtaggggt gcagcccctg gaagatcgcg tcctcggtga accgggcggc
     2521 gacctgctcc ggctcgtgcc cgtcgacggc ggccttccac tggtcgagga cgccgcgcag
     2581 gatcgcttcc gtgtcgctgt ccttcgtgct gttcatcagg attctcccct tgtcgtgttc
     2641 cgtcagtgac cggcgctcat gccgccgtcg acgtggagga tctcgccggt gacgaacggg
     2701 gcgttctcca ggtagatcac ggcgtcgacg atgtcgctcg tctcgcccat ccggccgacc
     2761 gggtgcagcc cggcgagggc ctcgtgggtc tcctcggcgt gcatcggggt ctttatggtg
     2821 cccggcgaaa cggcgttggc gcggatgccg cgcgtggcgt actcgatggc gagggacttg
     2881 gtggcggact ggaggccgcc cttggtcaac gaggcgagta cggacggcac gttggagtcg
     2941 gcgttgtcga ccaggctggt ggtgatgttg acgatgtggc cgccgccctg ggcgagcatg
     3001 tgctcgacgg ccagctgggt gatgcggaag aagccggtga ggttcacgcc ggtcgccgcg
     3061 gcgtagtcgt cctgggtgta ctcgtggaag ggcttggcga ggaagatgcc cgcgttgttg
     3121 accagggtgt cgacacggcc gaaccgctcg accgcggtgg cgatgacgcg ttcggcggtg
     3181 gcggggtcgg cgatgtcacc ctgaacggtc acgatgcccg cgtcgtcggc gggagcgatc
     3241 gtgcgcgagg tggcgacgac ggcgtacccg agcttgcggt aggcctcggc gatgcccgcg
     3301 ccgaggccct gcgaggctcc ggtgacgacg gcgaccttct ggttctgaga gctcatggtg
     3361 atcttctccg agttccgtga ttccgcgatg aagcgggggg cttcttgact ggtcgccgat
     3421 cctgctagct actagccgac cggtcgacta tttggaactt aggcggggtg gagtggagaa
     3481 gtcaaaggtc aacagggtcc tggccaggac cgaattcctc cctgctggta ggcgcggcct
     3541 cccagtccag gtcagtgggc cggtggccct accggtgcgg atccccgtcc ggcagccagg
     3601 cgcccggggc gcggatgccg aggtccccca cgccgtcgca gagggcgtcg acgacggcga
     3661 ggacggccgg gcggtcctcg ttctcgcgcc agaccagcga ccaggtccag tagatctccg
     3721 gtgtggtgac cgggcgctgg accagatcgg gcggcagcgg ggtggtctga cccttggggg
     3781 agttgaccac cgggcgactg cagcggcgga cgtgatcgaa gaacgccggt ccggtgatgc
     3841 cgccgttgga gatgcgtacc gcgcgggccc cggtgtcctg ggccagctct tcggcgtaga
     3901 cgttccagga cgaccaggag gtggtgtcgt cgtcgaggag gacggtggtg tcccgggcgg
     3961 ccacgtcgct cgtgtcgtca ccgcctgcga cggcgtagag ccggtcggcg ccgatgagcc
     4021 gggcacgcag gccgcgttct tccaggtcct cggtccgcac ccagcacacc gcgaggtcca
     4081 ggccgcccgc ggcgacccgg gcggcctggg tgtgcgaggg cgcgacccat gcgtcgaggt
     4141 ggagttgggc cacggtggcg gtgcgggcgg tgaggtccga cgggagccag ttgacgtagc
     4201 cgagccgtac cggttccgat ccggacagcc gaccggcccg ccgctggagg tcgtcggccc
     4261 gctcgagcag ggcgcgggtg tgggggagca gggccgaacc ggccgcggtg agggacaccg
     4321 agcgacgatc gcgatcgaac aaccgcacgc ccaggtcgcg ttcgagcgtc ttgatctgct
     4381 gtgacagaga ggggcccgcg atcagcaggc gctcggcggc ccggccgaag ttcagctcct
     4441 cggcgacagc gacgaaatac cgcagttggc gcaactccac gctggtcatg ctacgtcggt
     4501 gcgaggccgc gcctctcagc agggaggaag cctgtcgtgg catcgccccg gtggcaggcg
     4561 gacgatggag cccatggaag cccgaccgag ggcggcccgg ccggacacct gacggcggac
     4621 gacctcagcg gtcctccgcc cggccaccat caccccacgc ggcgttccgg tgcccgccgg
     4681 acgtcccatc gagcggagca ggaccatgcg agagttcctg gtcgagatca ccaccacgat
     4741 ccccgagggc accactcagg acgaggtcga ccggcggcgc gccgccgagg ccgtccgtgc
     4801 ccgggaactg gccgccaccg gcaacctggc gcggctgtgg cgcccggtcg gcgagctgcg
     4861 cagcatcggc atctggtgtg ccggtgacga ggacgagctc cacgagaagg tgctcggcac
     4921 gctgccgctg cgcccgtgga tgagcctcac cgtcaccgcg ctcgagtccc accccaacga
     4981 cccgggccgg accgacgccg cgcggtgacg gcggggaccg gtgcgacatg gacctcgtca
     5041 tgagcgtacg agccctgcgc gcctccccgg ccggaagtgc cggcgcgccg cactcgccct
     5101 ggcgccacgt ggcccaggcc gccgcggcac tcgccgcggg catgggggtg ggccggttcg
     5161 tctacacccc gatccttccg ctgatgcacg ccggggcggg gctttccgcg ggtgccggcg
     5221 cgaacctggc caccgccaac tacatcggct atctcctcgg cgcgctcgtc ggcatcctgg
     5281 cccccgcggt ggtccgctcg cgggccctcc tgcgcgtctc cctcgtcgtg ctgaccggca
     5341 ccctggccgc gatgcccgcc acccacgaca ccgccgtgtg gttcgcgcta cggctgctgg
     5401 ccggggttgc cagcgcactg atcttcgtca tcgcggtcag ctcgctcctc agtcacctgc
     5461 gggcgtaccc ggctcatctg cccggatggg cgttcggcgg ggtcggcgcc ggcatcgccc
     5521 tgtcgggtct gctcgtgctg gtactgcgcc ccgtcgccga ctggcgggcc gcctggtggg
     5581 cctcggccgc actcgccgcg gtcctcgccg tcgcctcgtg gaacctccgt cccgaagtgc
     5641 ctcctacgac aacacaggcc ccgcaggccc cgcaggccgc ccaggccacc gcagtcactg
     5701 cggccaccgt ggatgacagc cgcgggccgc gcacgcaccg ctggttcacc gccctgttcg
     5761 cctcctacac gctggaaggc atcggctaca tcatcgcggg tacgttcctg gtcgccgcga
     5821 tcgagcagag ctccccggga ccgctcggcg gcggcgcctg ggtgctggtc ggtctggccg
     5881 ccgtgccctc ctccgcgctg tgggcccggc tcgggcgccg ttggtcccgc cccgacctgc
     5941 tgctcgccgc gctcgtcgtc caggcggtag gtatcgccct gcccgccctg atcggcggag
     6001 caccggccgc cctggtctcc gcggtgctgt tcggcgcgac gttcatcggg gtcagcaccc
     6061 tcgccctcgc caccggggcc cacctggagt tcccccgctc cgtcgcgctc ctgaccgccg
     6121 gatactccgt cggccagatc ctcggcccgc tggcggtggc gcccctgctt caccacggct
     6181 atcagcaggc cctggtcctg gccgcttccg tggttctcgt ggcggccgcg gccgccgccg
     6241 tgctgcgcat cggcttcccg caccacatgg tggtagtgcg agctaccgcc ccggtacgac
     6301 agcccgcacc gacggaatcc gccgcggacg cgggcagcca ccgatgactc agacgtggag
     6361 tccgtcatga ccacaccgcg ggacctgttg atgatcgcca tggacgtccc gtccagccgg
     6421 cccgtcgagc agggtgacct gtcgctggcc ctcgcgggag ccgaactggt cgacctcatc
     6481 gaggcccagg ccatcacgct ggaggacgac cgcatcgtgc ccggcgcgca gtggaccatg
     6541 ggcgaccgtc tgttggacgg ggccgtggcg tcgctggtcc ggcagaggcc gtacgagtcc
     6601 gtggacgact ggctgtggcg ccgcggccgc gggctgtccg cggcctatcg cgcggacctg
     6661 gaggcggagg gacggctcgc ccggccgcgc caccgctgga ttcccttcgg tggcggccgt
     6721 acggaagcgg ccgactcgcc ggaccgcagc cacgcggacg aacgctggac ctcgggcgag
     6781 cccatcctca ccgtcctcgc ggccgccgtg ggcatccacg acgagtcgac cgaggaggcc
     6841 gcgggtctcg tcgacgactc ggtcctggcc gtactggccg ccgtcaacgg cgcggtgacg
     6901 gaactggaag cggtacggca acggcgaagc atcgaagacg cggccttcga caacatctgg
     6961 cgaggcggcg acggcacatg acgtcatgca tcacgtcatg catcacgtca tgcatcacgt
     7021 catgcgtgac gtcattcacg aagtcatcca tgacgcgtcg gccttgtcga ttccctcact
     7081 ctccacgcac cggtcaagaa aggtgaatgt catagacagg cgcatgtttt cccggattct
     7141 caccatcgga acagccggag cctcgctacc gacgctcccg gcgatatcgg cctccgcctc
     7201 ggcttctctg tcggccgacg cgtccgggcc tggaatacac acctctttcg gcccgctgaa
     7261 gcagatccat gccggtgagc tgaacatggg atatgcggag gccggccccg cgcacggccc
     7321 cgctgtcgtc ctgctgcacg gttggcccta cgacattcac agctatgtcg atgtggctcc
     7381 caggctcgcc gcggcgggct accgggtgat cgtgccgtac ctgcgcggtc acggcaccac
     7441 acggttccgt tcggacaaga cgttccgcaa cgcccagcag tcggtgatcg cgctcgacat
     7501 catcgcgctc atggacgcgc tgaagatcga gaaggcgatc ctcgccggct tcgactgggg
     7561 agcgcggacg gccgacatca tcgcggtgct ctggccggag cgctgcaagg ccctggtctc
     7621 cgtgagcggt tatctcatca ccaaccgtga aacccaaaag gcgccgctgc cgccaaaggt
     7681 cgaatgggcg tggtggtatc aatactattt cgccaccgaa aggggacggc tcggcctcgc
     7741 acagtacaag cacgatttcg cgaaactcat ctggaagaac gtctccccga catggcactt
     7801 caatgacgcc acattcgatc ggaccgcgac cgccttcgac aatccggact gggttcccat
     7861 cgtgatccac aactaccggt ggcgactgag tctggccaag ggcgacccgc gattcgatcg
     7921 tctggaaaag cgacttgccc agagtcccgc catctcgcag ccgacgatca cccttgacgg
     7981 cgaactggat cccttcacgc cgccggggaa cggcgcctct tatcgcagtc atttcactgg
     8041 cgcgtacgac caccggacgc tgaagggcat cggtcacaac gtgccgcagg aagcacccga
     8101 ggcattcgct gcggcggtcg tcgacgtcaa cgccctctga gaccctctga gccctctgaa
     8161 cggtgtcgtg gtgggcgtca ggcgcccgcc acggcctcct gcggggctcg ggcgccgagc
     8221 agggccaggc agttcgccca cagggggctg agccgacggg tgttgttgta gagcttggcg
     8281 aacagcacct ggccctccaa ctgggcgacc accgcccgtg ccgcttcccg gctgtcgggg
     8341 gtggtgacct cctcgcgctc acgagcctcg gtgatgaccg actcgaccat ctcgacctgc
     8401 gcgtcgaaga tctcctgcag gcgggtgcgg atgggctcgg tgtggttgct catctccagg
     8461 ctgaggtttc cgaacaggca gccggacacg gtgccgcagc tctgctggcc ggcgcgctgg
     8521 ccggcctccg tctcctcgaa cagccggtac agccgccgca ggggttcctc gtcgctgttc
     8581 aggacgcgtg cccaggcgct tttctgggcg tcccagtgtt cgtcgagcac ggccagggcg
     8641 agggcttcct tggactcgaa gaagtagtag aagctgccct tgggcacgcc ggccgccttg
     8701 cagatctcgg ccacccccag cgccgagtaa ccgcgcagct cgatgagtga ctgcgcggcg
     8761 ctgaggatct tttccctggc gtcgctggtt cgtcccatga cgcaattgta cgaccggtcg
     8821 actatctctg actgtggtcg cgcccgtgcg gtgaaaccgt ctgatcgggt ggtgtgggag
     8881 cacgagctcc ggcagagggg cgagggcgtg ccgccacggg gtgcgcgtga gccgttccgg
     8941 cggggtggcg ggtctgttgg ggtgggcaca tcgccacgct cacgcaagcg ggtgacgggg
     9001 gagcctccat gaccgaaccg cccaacgagg acgccccacc cgacaccgga ccctggcccg
     9061 aggcccggcc ccaggtccgg tccgaggccc ggcccgacgc ccggcctgag gtgcggcctg
     9121 aggtgcggcc ccggatccgg ccggaggccc ggtccgaagc ccagtccgag gtccggtccg
     9181 aggtgtggcc cgacgcccgg cctgaggtgc ggccccagat ccggccgggg gcccagcccg
     9241 agatccggcc ccaggtccgg tccgaggtgc ggcccgacgc ccagcctgag gtgcggcccc
     9301 agatccggcc ggaggtccgg tccgagatgt ggcccgagat ccggcctgag gtgcggtctg
     9361 aggtgcggcc ccagatccgg ccggaggccc ggtccgaagc ccagcccgag gtccggtcca
     9421 aggcgcggcc cgaagttcag ccccaggccc ggcccgaggg ccagcgcaat acccgacgcg
     9481 gacctcagcg tcatgccaag cctcaacccg gctccgggac tcagcccagt tcccttcccg
     9541 gtcccgggac tcagccgaag cctcaacccg gctccgggac tcagcccact ccccaccccg
     9601 gcccccagcc ccagcgcggg ccccaccgcg agcctgtgac cgacccccac cctggccccc
     9661 ggctcgagcc cgggcctgag ccccactgcg ggcctgtgcc cgatcccccg cccgaccccc
     9721 gccccagccc cagcctcggc gctgtcccca acccgcaccc cagccccagc cccaacccca
     9781 gccccagccc cggccctgcg cccaacccca accctgcgtc caacccccgc cccagccccg
     9841 gccccaggcc cgtgcccgtg cccgtgcccg tgcccgtgcc cgcgcctgtc cccgggcttc
     9901 aacgtccgtc cggatcccca cccgatcccc cccctcgccc cgcgtcgagt tcgcggagct
     9961 tctggaggcg gagtttgttc ggcggtggcc ggggcgttcg gtggggctgg atgccgtgca
    10021 ccggtacgcg atggtcccgc cgggcaagct cctgcggccc tcgctggtgc tgcacgcggc
    10081 gctcacggtg ggtggggagc tgggggcggt gctgcccgcc gccgtcggta tcgagggggc
    10141 gcacgtcggc agcctcctgc acgacgacat catcgaccgc gacacccagc ggcgcggccg
    10201 cgcggccgtc cacacggagt tcggacccgc ccaggccgtc gtcgcgggca acgccctgtt
    10261 cttctcctgg ttcgcggcgc tctccgagtg ccgtcgcctg ggggtgcccg ccgaccgtgt
    10321 cgaacgcgcc atggccgtgc aggccgaggc cggggtggcg atctgccggg gcgccttcga
    10381 cgaactggcg atgcgcggcg acctggaact gggcgtgggc gcgtacgtgg cgatggcccg
    10441 ggcgaagacc gccgtgctgc tggcggccgc ctgccgcgtg ggcgccgttc tcggcggtgg
    10501 tgacgccccg acgacggaac tgctcggcga cttcggcgac cacctcggga tctgcttcca
    10561 gatccgcgac gacgtgctgc cgtacgaccc gatcgccgca cgcgccatgg gcaagccctc
    10621 cgacagcgac gtccgcaacc gccgccccac cctgcccgtg ctgatcgccc accgccgcgc
    10681 ggaccccaag agccgcgcgg cgctgcgcca tgccctgctg gacgagaccg aaccggagct
    10741 cgccctgtgc cggatccgcg ccgtgctgga gcggaccgga gccctggaca ccgcgcacgc
    10801 gatggccgac gactacgccc gcagggcccg cgaactcctc acccgactgc ccgccaccgc
    10861 ccacgtggcc cacgtccgcg ccctggcgct cctcacccgg ccggcgcact gagccgtaat
    10921 ggatcaccag gagcctgaga agggtgcctg cgcgggacgg cctcccggag gcatgatcgc
    10981 gcgttcagga tgcgttcagg ctgcgaccgc cacgtcgatc ggcgtggcgc gcaggcatgc
    11041 gcaacactga gccgatggac acgcggcctc ctgcggccgt ggccctgggg ggacgtcgat
    11101 gcaccccccc caggagcgaa cgttggacaa gacggaacgc gtcgccgacc cccaagtcgc
    11161 cgaccccggc gcctccgtga tgaagaagct gccagaggtg accctggcct tctggatcat
    11221 gaagatcgcc gcgacgacac tcggcgagac cgcgggcgac ctcttcgcac agaccctcaa
    11281 gctgggctac ttcctcacca cgatcctgct gttcctgatc ttcgtggtca cgctggtcgt
    11341 gcagctcagg tcgcgccggt acaacccctt cttctactgg acggtgatcc tttccaccag
    11401 catggcgggc accacgatgt ccgacttcat gaaccgtgac gccagcgcca agtacctctc
    11461 cggcggggcc acctcgttgg gttggggtcc gcagggcctg ggtctcgggt accccgcggg
    11521 cgccgcgatc ctgatctcgc tgctggtcgt gatcttcact gtctggaagt tcaccgggat
    11581 gacgttcgtc atccgcgaca tcgtgacctt ccgggccgag gccctcttct ggtcggcgat
    11641 cctcgtgtcg aacaccctcg gcacctcgat gggcgacttc ctgtcggaca gttccgggct
    11701 cggttacgcg ggcggcgcgc tgctcgtcac cgggctgctc gcggtcctcg tcgcgctgat
    11761 gggcgtcccc gcggtgccga acgtgctgct gttctggatc gccttcgtcc tcacccgccc
    11821 gctcggcgcg accgcgggcg acttcctcac caagccgacc gccaagggcg ggctcgacct
    11881 cggtacggcg ggttcgtcgg ccgtgctgtt cgcggtgctc gtcggtctca tgggctatgc
    11941 ccacctgcgg gagcgcagga cgctcgccac ctgagaccgg cgagccaggc ctgatccgaa
    12001 aggcacgccc cgacagcccc tacccgggca gactctcgcc gagcatgcgc agcagatcgc
    12061 cggtggcgtc cagcgcgccg aacgcgggca gggcgccgag ggcgaggacg gcgacgccga
    12121 tggaccacag gttcggcggc ggggccgtct gcagggcggc gatccggcgg gtgaccgcgt
    12181 gttcggagaa gctcagggcg cagcccggcc gggcgcgttg ggcgacaagg gcggcccggg
    12241 cgagggcgcg ggcggtggta cggcggtctc cgacgcgccg cgcggcctcc tcgtcggccc
    12301 agcgctccac caggaaggcg acggtggtgc gcacgggtgc gagcgccggg ttggcggcgg
    12361 cggccagggt caccgcggtc gacagcaccg agtggcggtg ggtgagatgg gcgcgctcgt
    12421 gggccagcag tacgcgccgc tccgccggtt ccagcgcgcc gagcatggcg gccgtgacca
    12481 ggatccggcc cggcgtgccg gggatcgcga aggcccgggg cgtcgaggag gcggcgacga
    12541 tgagttcact gtcgggcgga tgtccctcgc acagccgctc gaggaagcgg tgggtcgcgt
    12601 agtgggcgcg cagggcgcga acgagccgga agccgatcag ccacaggagc atgatcgcga
    12661 cgacggcgat cgccgccggg accggttcgg gcagccgccg cccgtcctca ccggcctccg
    12721 tggccacgtg cggcgcctcg ttgaccaggg tggcggcgag caggagcagc gcccaggtgg
    12781 aggcggtggc ggccagtacg gcggcgatgg tgaggacccg ggcggccagc gcgggggaga
    12841 ccttgaggcc cacttgcggt gcgattgccg tcagcagcag cggcaggacg agggggatgt
    12901 agacgtcgat cctcacatcc cgctcccccc gaggagatcc cgcagggcct cttcctcctg
    12961 ggggctcagg ccggtgacga actgctggag ggccgcgatc gggtcgggtc cccggtcgag
    13021 cgcctcgtgc atggcctcgg cggtcagttc ggcggcgttc ttcgcgggcc ggtacgcgcc
    13081 gcgtcgaccg tcgacgtcac gcaggaccag acccttgtcg tacaggcgtt tgaggatggt
    13141 gtgaacggtg ttgtaggcga ggttgccgcc gatctcaccc tggatgtcgg cgggggtgag
    13201 ggcctcctcg gtggcccaga gggcggcgag gacctcgctc tccagctctc cggcgctgcg
    13261 tcgttccgct ctgccgtggg ggcctgtgcg agccatgtcc gtcaccttac agcgcgtagg
    13321 ggcgcggggg gtggtgaggg cgtacgagtg cgcccagggg cgaacgaggg tgtgtccccg
    13381 gactgcatcc ccgctcgatc cacggtaact tgaccgtgtt ttgcgcaact tcctccttca
    13441 ccctacgtct tgtagggtga agaaccctac agaatgtagg gcgaagggtg gatgatggcc
    13501 aagaccgtga accttccgct catcggcgcc catcgccaca gtccgccctc gacggggcgc
    13561 atctttggac ggccgcacgg tcagcagtgg ctggccctgg tcgcgggcgc cttcaccctg
    13621 gcccaactga tcctcgtacg gccgggcatg gggctcggct gggacgagac cgtctacgtc
    13681 agccaggtcg gctcacatgc ccccgccgcc ttcttcagcg ccccgcgcgc ccgcggagtg
    13741 tcgctgctgg tggcaccgat cgcgtcctgg tcctcgtcca ccgccctgct gcgcgtctat
    13801 ctcgcggtgc tctccggact cggcctgttc gtggcgctgc gcgtctggcg cggactgttc
    13861 cccgtgcggg tactggcggc ggcgggcgcc ctgttcgcca cgctctgggt gaccctcttc
    13921 tacggcccgc aggccatgcc caactactgg gtcgcgatcg gcgccctggc ctgcgtcggc
    13981 tgcttcctgc gcgcccaggc cgaccgcttc gaccgggcgg cgctgtgggg cgtgggcctg
    14041 agcgccgcgc tgatggcgtg gatgcggccc accgacgcgg tctatgtgac cctgccgctg
    14101 ctcttcctcg tcgtgtgcgt acgccgctgg tggcgcccga ggctgctggt ggcgctcgtc
    14161 gcgggcctgg tcgccggcgc gggcgagtgg gtcgtcgagg cgtatgtcag ctacggcggc
    14221 ctggcccagc ggctctccga cggctccagg atccagggcg gcctgggctg gaacatagcc
    14281 ttcggcgacc agttgcgcag cctcggcggg cgcgtcctgt gccgtccctg caccggggcg
    14341 atgcccgccc cgccggtgat gctgtggtgg ttcgcgctgc ccgtcgtggc cgtcctcgga
    14401 gcggtgatcg ccgtcaaggc ccggcgcggg gtgaacagcc tgctgctcct ggcctgcgcc
    14461 gcggtggtcg gtttcccgta cctcttcatg atcggatacg cggcgccgcg cttcctgctg
    14521 cctgtctaca tcctgctggc catcccggcc gccgacgccc tgatccacct ggcgaccgcg
    14581 cccggcggcg gtcggcgacc ggtggccgcc accctggtgg cgctcggcct ggccgggcat
    14641 ctcgcggtgc agttcgcggt gctggagcac accgtgcacg gcaccaccgt ctcccaccag
    14701 gactgggccg acaccgcgac gcagctgcac cggctggggg tgaagccgcc ctgcatgctg
    14761 actggctacg aggacgtccc gatcgccttc tacaccgggt gctcctccgt cgacaccggc
    14821 ggccacaacg ccaacaccac cgccgacgcc atagtgcggg ccggacagcg gatcccggtc
    14881 ggcgtgctga ccacaccggg cgaaaagcca cccgcgtacg cccgcacgtg ggaagcgcac
    14941 cgcgtcggcc atctgacggt gtacgtcgca cccgccgtcc aggcaggcgg agcgacatga
    15001 ccctccttcc gcccggcgcc ccggcgacag ccgcgagcag gcgggtctcc ctgcatgccg
    15061 cggtgaccct cgccgtcgtg gtgggcgcgg tctgtctcgg ccggcgccac tggccggtga
    15121 tcgcgaccgg cgccggtcgg ctggccgtcg ccgaccgcgg ctggctgctc gtggcggccg
    15181 tcgccaccgt ggggacctgg gtgtgttcgg cgctcgccca acaaggggcg gtgacccggc
    15241 cgttgcccgc cgggcagctg gtggccgtcc agttcgcggc ctccgccgcc aaccatgtgc
    15301 tgcccgcggg cctcggcgcg ggcgcggtca acctccgctt cctgacccgg tgcggtctgc
    15361 cggtcgtccg gtcggcgacc gcgctcggtg tgaaggccac cgccggggcc gtctcgcgcg
    15421 gcttcctgat cgccgtgctc gcgctggcct gccccggcct gctccgtctg ccgcacatcc
    15481 cggcgacggc ggtcgcgatc gcgctcgccg tggtggtcac cgccgccgta ctgctgcgcg
    15541 ggccgttgcg gcgcgcgctg cgggccgtgc tggccgacgt ccgcgccgtg cacgaggtcc
    15601 cggcgcgcgc ggccgcgctg tggggcggct cgctggcctt cgccgcgctg cacgccaccg
    15661 tggtcgtcgc cgtggctcag gccctcgaac tgccgctgcc cccggcccag gtggcgctgg
    15721 cgtacctcgc cgcgagcagc gccgccgtac tcctgcccac gcccggaggg atcggctccc
    15781 tggacgcggc gctcgccgtg gccctcacgc tggccggagt cccgggcagc gcggcggcgt
    15841 cggtggtcct cggctaccgg ctgctgacgg tgtggctgcc cctgatcccc gggctcctgt
    15901 cactggccgt actggcccgc cgcaaggtcc tctgagcccg ccgcaaggtc cctccgggac
    15961 tccggcgccg ccccgctgtc ggcgctcgcc gaatgccgtg gcacctcagg gcggttcaag
    16021 ccggtagccg tgcccccgca gggtcgagat gcgcggtgtc cgggacggac gggacgccgt
    16081 gtccgtcagc cggcggcgca gtcccgccat ggtgacgtcg agcgtcttcg tcgagccgaa
    16141 ccagttgcag ctcaccctgg aggcggggct cgcgcaggac gacgcccggc tgcgccccgc
    16201 actggaggag gcgctggacg ccacccgacg gctgcacgac acggtggagg aggtgctgcg
    16261 gctcgcgggc tcgcccggcc cgccgggtgc cgtcgtgcgc gaccggtcgg tggtccacct
    16321 cctggcggag accgacgccc ggtggcacgg tctcttcgcc caggacggca ggcgcctgga
    16381 ctgcggcgtc caggacgccc cggcggacgt cctggtgccc ggcgggcccg tcgccgagat
    16441 cctcggcgtc ctcctggaca acgcccgtac gcacggccgg ggcagcgtcc gcgtcacggt
    16501 ccgcgacctc gacgacgccc tcgccttcga cgtcgccgac gagggaacgg tcaccgccga
    16561 gccggaagga ctgttcgcgc gcggacggac cggcggcggc aacggcggta cgggcatcgg
    16621 tctcgccctc gcccgcgacc tggccgtgtc gctcggcggc agactcttcc tgtcgggcgg
    16681 cgaccccacg acgttcacac tgctcgtccc cgtggcccct gtcgcccccg ccacccggta
    16741 gtcaggatgt gttcagggtc ccgctggcag ggtcggcctc atgactgaga cttctgagac
    16801 gcccggggct tatgtccgca gtggggcggc ccccggccac cgcctccgct ggaacaaggt
    16861 tcccgaggtc accgcgtact tctggatcat caaggtgctg tgcaccacgg tcggcgagac
    16921 cgcggcggac ttcctgaact cgaacctggg catgggcctg accggcgtgt cgctgctgat
    16981 gagcgcgctg ctgatagcgg tcctggtcgt tcagttccgc acgaaggcct accggcccgg
    17041 cgtgtactgg ttcgccgtgg ccctgatcag cgtcgtcggc acgctgatca gcgacaacct
    17101 caccgacaat ctgggcgtgt cgctgacgac ctgcaccacc gtgttcgccg tcgccctcgc
    17161 cgtcgtcttc gccatctggt accgccgcga gggaacgctg tccatccaca gcatcgacac
    17221 ggtgtcccgc gaggcctact actggctggc cgtgctgttc accttcgcgc tgggcacctc
    17281 ggccggcgac ctcgtcgcgg agaagatggc cctcggatac tgggtctccg cgatcctctt
    17341 cggccttgcc atcgccgcgg tggcggtcgc gcacttcgcg ctcggcctga acgccgtgct
    17401 gagcttctgg atcgcgtaca tcctgacccg cccgctgggt gcctcgatgg gcgactacct
    17461 ctcgcagccg accggcgacg gcggcctggg cctgggtacc acggtcacca gcgtgctgtt
    17521 cctcgcggtc atcctcgctc tggtggtgta cctgtcgatg acccgcaagg acgtcaccgc
    17581 gtccgagcgg gagctcagcc tccagtaggg gccgcgagca gaggtcttca gacgggacga
    17641 cgtgctcaac ccgcgggaag cgtgaccacg aacgtcgcgc cggaggtgcg ccgcgcgtcg
    17701 tggtccacct ccccgccggc ggagcgggcc aggcgtcgcg ccagcggcag cccgaggccc
    17761 gctccgccgt gtccgtcttc ggggtcggcg cgccggccgg gctggaagag ctgcgccgcg
    17821 aacgacgccg gtacgccggg accgtcgtcc ccgacctcga cgcgtacgcc gccgggccga
    17881 gcgcgggcca ggatctcgac ccgggtgcgc gcgtgccgta gggcgttgtc gagcagtggg
    17941 ctgacgatgc gctccagaag ggcgtccggc accccggcag acaaccgggc gtcgcaggcg
    18001 gtgacgacga cctccacgcc caccttcgtg gggccgaggc ggtccaccag gcggtgcagc
    18061 accggcagca cgtcggcggt gccgggcgcg gtggcggcgc tgtcgcgggc ctcgtcgagc
    18121 agggtgtcgc agatcgtgcg catggactgg gccgcgtcgg cgatcgccgc gtgggtggcc
    18181 ttggtgtcgg cgtcggagcg gggacgggct ccccaccagt cgagctcggc gatgatccgg
    18241 gcgagcgggt tgcgcagctc gtgcgacagc tcccgggtga gctgctgctc gtgccgcagc
    18301 agcgcgcgga tgcggtcgag gagggcgtcc agcgaaccgc ccagctgggc gagttcggtg
    18361 ggccgggtca cggcgccgaa gcgctcctgg gaggctatcg cgctccactg ggtggcgtgc
    18421 tcggtcatcg aacgcacggg acgcagggcg cggcccaccg ccagccgcgt cagcgcgtag
    18481 gtgcaggcga gcatcgcggc gtcgagggcg agggacgcga agagcatcgt gtcggccgag
    18541 ccgcggtacg gggagaggtc cagtgcggtg acgacggctg cggcgccctt gccaccgggc
    18601 accgggcgcg agcacagccg tacctcaccg tgactgtgca cggtgacaca gtgccgggca
    18661 ccgcgcgcca cgagccggcc ggcggcgcgg gtcagcgggc tggtggaggt ggcggacgag
    18721 ggcttctcga gcagccggcc gcccgagtag atccacacgt tcgtgtcgag gagttcctcg
    18781 ccaggggtct ccaggacccg cacccgggag ccgtcggtga cgacggtcgc ggcgacggcg
    18841 gcggcccggg tgcgcagctc gtcgtccgcc tggtgctgaa ggtgacggcg cacgaccgtg
    18901 ttgaacgcga ccgtgaggat caccatcagg atcgtcgccg tggtgagcgc gaccagggag
    18961 agccggcctc gcagggtgcg cggccaccat cgtgaggcga acgccctcat gacagccggt
    19021 ggcctatgcc gcgcgccgtg gtgatggcca gtgcgctgcc gccgtcccgg agcttgcggc
    19081 gcagccgggt cagatactgg tccagcgtgt tgtcgctgac ctgggcgcct tccggccagc
    19141 cggccctgat cagctcccgc ctgcggacga tgtccccgga ccccgccatc agcgccgcca
    19201 gcagccggaa ctccgtcggg gtgaggccga cccgggtgcc gtcgacggtg aggctgtgcc
    19261 cgaccgggtc caggaccagg tccccggccg tggtggccgg gagcggtccg ctgcgcttga
    19321 gcgccgcccg cagccgggcg gccagctccg tcaggtggaa cggcttgggc agatagtcgt
    19381 cgccgccggc cgagaagccc gccagccggt ccgtgaggtg gtgatgggcg gtcaggaaga
    19441 tgacgggcga gaggaagccg ttggctctga tcgcctggca cacgtcccgc ccgtccgcgt
    19501 cgggcagccc gacgtccagc acggccgcgt cgacgtcgtc cccggccagc cgcagcgcgg
    19561 tcgccccgtc cggggcgggc acggtgtcga agccctcctc gcgcagcccg cgcagcagga
    19621 cgtcacgcag ggcgtgatcg tcctcgacga ccaggatcgt gtgccgcatg gtcctccttc
    19681 agccgctccg gaagggtgct tgcctgttcc ccgtagccgt agccgtagcc gtagccgtag
    19741 ccgtagccgt agccgtagcc gtagccgtag ccgtagccgt gggcctacgc cgagaccagc
    19801 aacggccgca gcagccgcga gtccgtcagc cggctcgcca gcgggtcgga gagtctgcgc
    19861 aggagggtcg tcagcagcat cgcgatcagc gtgccgacca ggacaccggc gaccacgtcg
    19921 tgcggatagt gcgcgccgac ccagacccgg gagacggcca tcagacaggc gcccagcagg
    19981 gctatggtgc cgaggcgacg ggagacgtag agcagggcca cggcggccgc ggcggcgatg
    20041 accgtgtgat tgctggggaa ggaccagtcg cccggcgcag gacacgcctc cagcgtcttc
    20101 acgtgcaggc tctggcaggg gcggtcctcg cgtacgacca tcttgaacag ggagttcacc
    20161 ccgaacgcca cgacgacgat caccggcacc gcgagcgcga ccatcgccgc ttgggcgctg
    20221 ctgcgacgcg cctgccacca gcccacgagc atgagaacgg cgaacagcgc cagcccgtac
    20281 gtcgaccagg cggacaccag gctgtccagc caggacgggg agtcatgggc gagattcacc
    20341 acgtaggtgt aggtggagcc gtcgatcgac gacccgttga acgcgaggat catccctcgg
    20401 cacccttctc cgcggtcgtg gccgcggcct tgcgggagcg gcggaactcg gcggccagcg
    20461 ggatcagcga cacgatgacg atcacggcga tgatcgggag cagatagcgg tcgacgttcg
    20521 gaatcgacga gcccagtgcg tagcccgcga gggtgaggcc gatgctccag acgagaccgc
    20581 cgacgacctg ccacacggtg aacgtgcggg cggggacctg gagggcgccc gccatcgggt
    20641 tcagcaccgt gcgcacgacc gggacgaagc gggccagcac gatcgccttc gcgtggccgt
    20701 accgctccag cagttcctcg gcgcgcttgg ccccctcgtg cagccggggc gagccgctgc
    20761 gggcgagcag cgcgccgccc gccttgcgtc cgatgagata gccgcactgg gagccggcca
    20821 gcgcgcccac ggcggcgcag accaggagcg gccccaggga gagcttcagt ccgccgtggc
    20881 ccgaccccgt gcacagcagg cccgccgtga ac
//
