LOCUS       NZ_BMTZ01000029        29773 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces variabilis strain JCM 4422 sequence29, whole genome
            shotgun sequence.
ACCESSION   NZ_BMTZ01000029
VERSION     NZ_BMTZ01000029.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces variabilis
  ORGANISM  Streptomyces variabilis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces griseoincarnatus
            group.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 77434)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: BGI assembly pipeline
            Genome Coverage                   :: 156X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014649935.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:37:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,743
            CDSs (total)                      :: 6,668
            Genes (coding)                    :: 6,496
            CDSs (with protein)               :: 6,496
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 172
            CDSs (without protein)            :: 172
            Pseudo Genes (ambiguous residues) :: 0 of 172
            Pseudo Genes (frameshifted)       :: 61 of 172
            Pseudo Genes (incomplete)         :: 147 of 172
            Pseudo Genes (internal stop)      :: 11 of 172
            Pseudo Genes (multiple problems)  :: 42 of 172
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:23:51
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 23557
            Orig. end                         :: 53330
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMTZ01000029.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..29773
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NI-siderophore"
                     /region_number="1"
                     /rules="IucA_IucC"
                     /tool="antismash"
     cand_cluster    1..29773
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..29773
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[14000:15773](+)"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      14001..15773
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     gene            complement(576..1733)
                     /locus_tag="IE148_RS29375"
                     /old_locus_tag="GCM10010287_59330"
     CDS             complement(576..1733)
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003969014.1"
                     /locus_tag="IE148_RS29375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_59330"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_048457772.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 3.2e-33, bitscore:
                     107.0, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.5e-28, bitscore:
                     91.1, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 5.9e-48, bitscore:
                     155.0, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRTVFNEDHEAFRETIRAFIEAEVVPVYDEWFAAGQAPRDFYYK
                     LGELGIFGISVPEEYGGAGMDTHKFEAVLYEETARAGVQFGGSGVHVLLALPYIKMLAT
                     DEQKKRFLPKFVSGEEMWAIAMTEPGTGSDLAGMKTTAKLSEDGTHYVLNGAKTFITGG
                     VHADKVIVCARTAAPTAEDRRHGISLFAVDTKSEGYSVGRKLDKLGLKTSDTAELAFVD
                     VKVPVEDLLGEENKGFYYLGHNLASERWGIAFGAYAQAKAAVRFAKQYVQERTVFGKPV
                     AHFQNTKFELAACQAEVDAAEAVADRATEALDAGELTPAEAASAKLFCTEVAHRVIDRC
                     LQLHGGYGYMNEYPIARLYADNRVNRIYGGTSEIMKSIIAKDMGL"
     misc_feature    1922..1931
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            complement(1942..2544)
                     /locus_tag="IE148_RS29380"
                     /old_locus_tag="GCM10010287_59340"
     CDS             complement(1942..2544)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010046981.1"
                     /locus_tag="IE148_RS29380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_59340"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_189366526.1"
                     /transl_table=11
                     /translation="MATRTDAPTRREQILKEAARLFAERGFHGVGVDEIGAAVGISGPG
                     LYRHFAGKDAMLAELLVGISESLLTGAKRRLAEANGAGGVAPGAVLDSLIEGHIDFALD
                     DRPLITLHDRELDRLRDADRKLVRQLQRQYVELWVAVVRRLYPDLTEPAARSAVHSVFG
                     LLNSTPHLTRPGSLPDRAGTAELLHRMARGAFAAAGA"
     misc_feature    2532..2552
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.72"
                     /tool="antismash"
     misc_feature    complement(2544..2557)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.36"
                     /tool="antismash"
     gene            2632..4248
                     /locus_tag="IE148_RS29385"
                     /old_locus_tag="GCM10010287_59350"
     CDS             2632..4248
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015660219.1"
                     /locus_tag="IE148_RS29385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_59350"
                     /product="carboxyl transferase domain-containing protein"
                     /protein_id="WP_189366527.1"
                     /transl_table=11
                     /translation="MHEAPELHSAADPASEAFRANEEAHRALVEELRGKLAAAAFGGGE
                     RARARHTARGKLLPRDRVDTLLDPGSPFLELAPLAADGMYDGQAPAAGVIAGIGRVAGR
                     ECVVVANDATVKGGTYYPMTVKKHLRAQEVALDNRLPCVYLVDSGGAFLPMQDEVFPDR
                     DHFGRIFYNQARMSGAGIPQIAAVLGSCTAGGAYVPAMSDEAVIVRGQGTIFLGGPPLV
                     KAATGEVVTAEELGGGEVHSRVSGVTDHLAEDDAHALRIVRQIVSTLPGRGELPWRVEP
                     VAEPKVDPAGLYGAVPVDSRTPYDVREIIARITDGSRFAEFKAEYGQTLVTGFAHIHGH
                     PVGIVANNGILFSESAQKGAHFIELCDQRGIPLLFLQNISGFMVGKDYEAGGIAKHGAK
                     MVTAVACTRVPKLTVVVGGSYGAGNYSMCGRAYSPRFLWMWPNAKISVMGGEQAASVLA
                     TVKRDQLEARGEDWPADEEEAFKAPVRAQYERQGNAYYATARLWDDGVIDPMDTRQVLG
                     LALTACANAPLGDPQFGVFRM"
     gene            4275..6299
                     /locus_tag="IE148_RS29390"
                     /old_locus_tag="GCM10010287_59360"
     CDS             4275..6299
                     /EC_number="6.4.1.2"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019525190.1"
                     /locus_tag="IE148_RS29390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_59360"
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_086703321.1"
                     /sec_met_domain="ATP-grasp_3 (E-value: 1.5e-07, bitscore:
                     23.8, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 1e-08, bitscore: 27.1,
                     seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 2.2e-11,
                     bitscore: 35.7, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFDTVLVANRGEIAVRVVRTLRSLGVRSVAVYSDADAGARHVREA
                     DTAVRIGPAPAAESYLSADRLLEAAARTGARAVHPGYGFLAENAEFARACEAAGLAFIG
                     PPADAIALMGDKIRAKETVKAAGVPVVPGSSGSGLTDEQLVDAAREIGMPVLLKPSAGG
                     GGKGMRLVRDETRLADEIAAARREARASFGDDTLLVERWIDRPRHIEIQVLADGHGNVV
                     HLGERECSLQRRHQKIVEEAPSVLLDDRTRAAMGEAAVQAARSCGYRGAGTVEFIVPGD
                     DPSAYYFMEMNTRLQVEHPVTELITGLDLVEWQLRVAAGERLAFGQDDVRLTGHAVEAR
                     LCAEDPARGFLPSGGTVLRLREPQGDGVRTDSGLSEGTEVGSLYDPMLSKVIAYGPDRA
                     TALRKLRAALAETVTLGVQTNAGFLRRLLAHPAVVSGELDTGLVEREADSLVGGEVPAE
                     VYAAAALLRQAALEPAAAPGWRDPFDAADGWRMGGGRAWTAHHLRAAGHDPVTVRVRAA
                     ADGGTELLLPGADTPVRASAGPLEGHRFTCALDGVAYTFAALPDGTWLGRDGDAWQVRD
                     HDPVAASLTRAGQAGADSLTAPMPGTVTVVKVAVGDEVDAGQSLLVVEAMKMEHVISAP
                     HAGTVTELDVSPGTTVAMDQVLAVIAPVETAAPAEGETA"
     gene            6296..7243
                     /locus_tag="IE148_RS29395"
                     /old_locus_tag="GCM10010287_59370"
     CDS             6296..7243
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019525189.1"
                     /locus_tag="IE148_RS29395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_59370"
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_189366528.1"
                     /sec_met_domain="HMGL-like (E-value: 7.5e-49, bitscore:
                     158.7, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNASELGLPMAVPAEGLPARVRIHEVGARDGLQNEKATVPTAVKA
                     EFVRRLAGTGLTTIEATSFVHPKWVPQLADAEELYPAVSDLPVELPVLVPNERGLDRAL
                     ALGARRVAVFASATESFAKANLNRTVDEALAMFEPVVARAKEQDVHVRGYLSMCFGDPW
                     EGAVPVPQVVRVCRALLDMGCDELSLGDTIGVATPGHVTALIAALTEAGVPVPALGVHF
                     HDTYGQALSNTLAALQQGVATVDASAGGLGGCPYAKSATGNLATEDLVWMLRGLGIDTG
                     VDLGRLVATSVWMAAHLGRPSPSRTVRALSHQEQ"
     gene            7248..8408
                     /locus_tag="IE148_RS29400"
                     /old_locus_tag="GCM10010287_59380"
     CDS             7248..8408
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019325537.1"
                     /locus_tag="IE148_RS29400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_59380"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_086703323.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.7e-38, bitscore:
                     123.9, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 4.9e-24, bitscore:
                     76.6, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2.7e-51, bitscore:
                     165.9, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDHKLSPELEELRRTVEEFAHDVVAPKIGDFYERHEFPYEIVREM
                     GRMGLFGLPFPEEYGGMGGDYFALGVALEELARVDSSVAITLEAGVSLGAMPLHLFGTE
                     EQKREWLPRLCSGEILGAFGLTEPDGGSDAGATRTTARLDEATGEWVINGTKCFITNSG
                     TDITGLVTVTAVTGRGPDGKPRISAIIVPSGTPGFTVAAPYSKVGWNASDTRELSFQDV
                     RVPAANLLGEEGRGYAQFLRILDEGRIAIAALATGLAQGCVDESVKYARERHAFGRPIG
                     ANQAIQFKIADMEMKAHTARLAWRDAASRLVAGEPFKKEAALAKLYSSTVAVDNARDAT
                     QVHGGYGFMNEYPVARMWRDSKILEIGEGTSEVQRMLIARELGLAG"
     misc_feature    8470..8485
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
     misc_feature    8471..8484
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
     misc_feature    8540..8558
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: strong, score: 32.19"
                     /tool="antismash"
     gene            8604..9647
                     /locus_tag="IE148_RS29405"
                     /old_locus_tag="GCM10010287_59390"
     CDS             8604..9647
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003990430.1"
                     /locus_tag="IE148_RS29405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_59390"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_086703324.1"
                     /transl_table=11
                     /translation="MPNATTARLSRRGLLAAGGALGLGAVLTACGDDDAKDGGADTKGA
                     AKSGPWSFKDDRGTTVKLGEAPKNIVAFTGVAAALYDYGIEVKGVFGPTTTKDGKADVQ
                     AGDMDVSKVTVLGNVWDQFNVEKYAALAPDVLISTMFDDAGTLWYVPEASKDKIAKLAP
                     SVGISVFDRQLTAPLQRMWELAESLGADMTAAKVTEAKKRFEAASERLRKAAKAKPEIK
                     VLVGSASPELFYVSGSNLSIDLEYFKALGVNFVEPTEAAKKATGGWFESLSWENVDKHK
                     ADVIMMDDRSSAIQPADITEATWKQLPAVKAGQVIARSTEPILSYDKCVAPVEALAEAI
                     EKARKVS"
     gene            9718..10587
                     /locus_tag="IE148_RS29410"
                     /old_locus_tag="GCM10010287_59400"
     CDS             9718..10587
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1200: vibriobactin
                     utilization protein ViuB"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010046991.1"
                     /locus_tag="IE148_RS29410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_59400"
                     /product="siderophore-interacting protein"
                     /protein_id="WP_086703325.1"
                     /transl_table=11
                     /translation="MTTAVAAPFRFFALQVAGTRRLGPSLVRVTFTGPELRDFRSDGRD
                     QSLSLFLPHPGQDAPVVPLELGDDWWQGWRELPDDVRAVMRSYTLRALRADALGRTAEI
                     DVDFVLHGVGEAGPSAEAGPASRWAARAAAGDRVLLLGPAIADNRAIRFRPPEDASTVL
                     LWADETALPAAAAVLESLPAGIRAQVWLEVPHAGDVQELPTAADAEITWFVREGVAAPE
                     TPTALDAVRQTALPSPERAYVWIAGESGRVKQLRRHFVRERGVDRRRVTFVGYWRRGLT
                     EEQLREQV"
     misc_feature    complement(10628..10643)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.38"
                     /tool="antismash"
     misc_feature    10671..10689
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: strong, score: 32.19"
                     /tool="antismash"
     misc_feature    complement(10676..10694)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.4"
                     /tool="antismash"
     gene            10747..12189
                     /gene="desA"
                     /locus_tag="IE148_RS29415"
                     /old_locus_tag="GCM10010287_59410"
     CDS             10747..12189
                     /EC_number="4.1.1.18"
                     /NRPS_PKS="Domain: Aminotran_5 (140-265). E-value: 7.4e-09.
                     Score: 26.9. Matches aSDomain:
                     nrpspksdomains_IE148_RS29415_Aminotran_5.1"
                     /codon_start=1
                     /gene="desA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180: Decarboxylase, pyridoxal-dependent"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006140623.1"
                     /locus_tag="IE148_RS29415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_59410"
                     /product="lysine decarboxylase DesA"
                     /protein_id="WP_189366529.1"
                     /sec_met_domain="Aminotran_5 (E-value: 2.3e-08, bitscore:
                     25.5, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSHLLNDTTAEHYRRSVTEGVERVAAKLAATDRPFTGVTADDLA
                     PRIDAIDLDRPLRDTTAALDELEDVYLRDAVYFHHPRYLAHLNCPVVIPAVLGEAVLSA
                     VNSSLDTWDQSAGGTLIERKLIDWTAARIGLGPAADGVFTSGGTQSNLQALLLAREETK
                     TEELTKLRVFASEVSHFSVQKSAKLLGLGPDAVVVVPVDHDKRMQTVALAHELERCAEA
                     GLIPMAVVATAGTTDFGSIDPLPEIAGLCEQYGAWMHVDAAYGCGLLASRKYRHRIDGI
                     ERADSVTVDYHKSFFQPVSSSAVLVRDAATLRHATYHAEYLNPRRMVTERIPNQVDKSL
                     QTTRRFDALKLWMTLRVMGADGIGALFDEVCDLAAEGWKLLAADPRFDVVVEPSLSTLV
                     FRYIPAAVTDPGEIDRANLYARKALFASGDAVVAGTKVSGRHYLKFTLLNPETTTADIT
                     AVLDLIAGHAEQYLGESLDRAC"
     aSDomain        11167..11541
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE148_RS29415_Aminotran_5.1"
                     /evalue="7.40E-09"
                     /label="IE148_RS29415_Aminotran_5.1"
                     /locus_tag="IE148_RS29415"
                     /protein_end="265"
                     /protein_start="140"
                     /score="26.9"
                     /tool="antismash"
                     /translation="GVFTSGGTQSNLQALLLAREETKTEELTKLRVFASEVSHFSVQKS
                     AKLLGLGPDAVVVVPVDHDKRMQTVALAHELERCAEAGLIPMAVVATAGTTDFGSIDPL
                     PEIAGLCEQYGAWMHVDAAYG"
     gene            12173..13465
                     /locus_tag="IE148_RS29420"
                     /old_locus_tag="GCM10010287_59420"
     CDS             12173..13465
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080: lysine/ornithine N-monooxygenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006131547.1"
                     /locus_tag="IE148_RS29420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_59420"
                     /product="lysine N(6)-hydroxylase/L-ornithine
                     N(5)-oxygenase family protein"
                     /protein_id="WP_189366530.1"
                     /transl_table=11
                     /translation="MTALADTTKPTYDFVGIGLGPFNLGLACLTEPVDELAGVFLESKP
                     DFAWHAGMFLDGAHLQTPFMSDLVTLADPTSPYSFLNYLKEKGRLYSFYIRENFYPLRV
                     EYDDYCRWAAAQLSSIRFGTTVTEVTWDETAEVYVVATSTGTTYRGRHLVLGTGTVPFV
                     PEACRGLEGGLFHNAQYMRRKAELLEKKSVTIVGSGQSAAEIYYELLSGIDAHGYQLNW
                     VTRSPRFFPLEYTKLTLEMTSPDYIDYFRALPEDTRYRLEKQQKGLFKGINSDLIDAIF
                     DLLYQKNVESGGRGVPTRLLTNSSLTTARYQDGTYTLGFRQDEQGKDFEIATEGLVLAT
                     GYHYEQPAFLEPVRDRLRFDGHGRFDVARNYAIDVTGRGVFLQNAGVHTHSITSPDLGM
                     GAYRNASIVRELLGTEYYPVEKSIAFQEFAV"
     gene            13462..14004
                     /locus_tag="IE148_RS29425"
                     /old_locus_tag="GCM10010287_59430"
     CDS             13462..14004
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203: putative siderophore biosynthesis protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019525183.1"
                     /locus_tag="IE148_RS29425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_59430"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_048457762.1"
                     /transl_table=11
                     /translation="MSTIGTFTIRPLDPEKDAELLHRWVTHPKAAFWMMQDARLEDVER
                     EYMRIAAHEHHHAYLGLHDGEPAFLMEKYDPRHVELVGLYEPEPGDVGMHFLVAPTDRP
                     VHGFTRAVITAVMEELFADPATRRVVVEPDVGNKAVHALNEAVGFEPEREIDKPEKRAL
                     LSFCTREQFEAARGASA"
     gene            14001..15773
                     /locus_tag="IE148_RS29430"
                     /old_locus_tag="GCM10010287_59440"
     CDS             14001..15773
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011028585.1"
                     /locus_tag="IE148_RS29430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_59440"
                     /product="IucA/IucC family siderophore biosynthesis
                     protein"
                     /protein_id="WP_189366531.1"
                     /sec_met_domain="IucA_IucC (E-value: 1e-81, bitscore:
                     266.2, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLSDAVAHLSPHRWARANRLLIRKALAEFAHERLVTPEPAGDGR
                     YVVRSDDGETRYTFTAKLRGLDHWQVDAGSITRHRDGVELELAALDFFIELQKSLGLSD
                     EILPVYLEEISSTLSGTCYKLTKPEVTSAELVDAGFQAIETGMTEGHPCFVANNGRLGF
                     GVHEYRQYAPEAANPVRLVWLAAHRSRAAFTAGVGIEYESFVRQELGEETVDRFHDVLR
                     AQDLDPADYLLVPVHPWQWWNKLSVTFAAEVARRHLVLLGEGDDEYLAQQSIRTFFNRS
                     HPEKHYVKTALSVLNMGFMRGLSAAYMEATPAINDWLARLIDNDPVLRSTGLSIIRERA
                     AVGYRHLEYEQATDRYSPYRKMLAALWRESPVTSLEDGESLATMASLVHVDHEGRSFAA
                     ALIERSGLTPAEWLRRYLRAYYVPLLHSFYAYDLVYMPHGENVILVLEDGAVKRAVYKD
                     IAEEIAVMDPDAVLPPEVSRIRVEVPDDTKLLSIFTDVFDCFFRFLAANLAEEGVLDED
                     GFWRTVAEVTREYQASVPELTDKFARYNLFAPEFALSCLNRLQLRDNKQMVDLADPSGA
                     LQLVGTLKNPLAAF"
     gene            15991..16881
                     /locus_tag="IE148_RS29435"
                     /old_locus_tag="GCM10010287_59450"
     CDS             15991..16881
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019525180.1"
                     /locus_tag="IE148_RS29435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_59450"
                     /product="DUF4429 domain-containing protein"
                     /protein_id="WP_189366532.1"
                     /transl_table=11
                     /translation="MAEIIQKDGTWTFDGETLRLTPGRDKNVGLLRRTLGELALPLEAL
                     AGVSLEQGKKSGRLRLRLRDGADPLLHATGGRLTEPHDPYQLTVESDRYGVAEYFTEEV
                     RTALLLEQIPSGPVTGYLLPGPPLPLSVSAGDGTVSFDGERVRLEWNWKTEDAKAAAGP
                     RTLAVADLEGVDWQPAAGLENGHLRFLVRHAPTKVPAKYDPNAVELWGFKKDPLMALVA
                     AAVQARLPHPSTPAAPALEGPGAPETDRPAPPGPAEDDHDALLRRLRELGELHRSGILT
                     DEEFALAKQAVLKRM"
     misc_feature    16912..16925
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.31"
                     /tool="antismash"
     gene            16957..17214
                     /locus_tag="IE148_RS29440"
                     /old_locus_tag="GCM10010287_59460"
     CDS             16957..17214
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020131788.1"
                     /locus_tag="IE148_RS29440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_59460"
                     /product="hypothetical protein"
                     /protein_id="WP_006131553.1"
                     /transl_table=11
                     /translation="MHDELVDHLTRSTPLSRGEALRVIQDVLAYFDETTEEYVRRRHRE
                     LQAQGLVNATIFQRIEADLRYRAVAPPELSLRQLRRIVYG"
     gene            17227..19044
                     /gene="glmS"
                     /locus_tag="IE148_RS29445"
                     /old_locus_tag="GCM10010287_59470"
     CDS             17227..19044
                     /EC_number="2.6.1.16"
                     /GO_function="GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA]"
                     /GO_process="GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="glmS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980526.1"
                     /locus_tag="IE148_RS29445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_59470"
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="WP_048457759.1"
                     /sec_met_domain="GATase_7 (E-value: 1.3e-17, bitscore:
                     56.1, seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGIVGYIGRREVAPLLLEGLQRLEYRGYDSAGIAVTSPKTGTLK
                     TVKAKGRVRDLEAKVPARFKGTTGIAHTRWATHGAPSDVNAHPHLDAEGKVAVVHNGII
                     DNAGDLRRKLEADGVEFLSETDTEVLVHLIARSQAEKLEDKVRETVRLIEGTYGIAVLH
                     ADFPDRIVVARNGSPVVLGIGEKEMFVASDIAALVAHTRQIVTLDDGEMATLKADDFRT
                     YTTEGTRTTAEPTTVEWEAASYDMGGHDTYMHKEIHEQAEAVDRVLRGRIDDRFSTVHL
                     GGLNLDAREARRIRRVKILGCGTSYHAGMIGAQMIEELARIPADAEPASEFRYRNAVVD
                     PDTLYVAVSQSGETYDVLAAVQELKRKGARVLGVVNVVGSAIAREADGGVYVHAGPEVC
                     VVSTKCFTNTTVAFALLALHLGRTRDLSVRDGKRIIEGLRRLPAQIAEMLEQEEQIKKL
                     ALEYAEARSMLFIGRVRGYPVAREASLKLKEVSYIHAEAYPASELKHGPLALIEPALPT
                     VAIVPDDDLLEKNRAAMEEIKARSGRIVAVAHQEQEKADHTIVVPKNEDELDPILMGIP
                     LQLLAYHTALALGRDIDKPRNLAKSVTVE"
     gene            complement(19160..19687)
                     /locus_tag="IE148_RS29450"
                     /old_locus_tag="GCM10010287_59480"
     CDS             complement(19160..19687)
                     /GO_function="GO:0032559 - adenyl ribonucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019325548.1"
                     /locus_tag="IE148_RS29450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_59480"
                     /product="universal stress protein"
                     /protein_id="WP_048457758.1"
                     /transl_table=11
                     /translation="MAGHEFFEPADRKRPVADPTASEPLAAEESRHARDPAFRHGVVVG
                     FDGSTSSERALAYAIGMARRSGSGLIIVHVANRLPTTVWAGCEPPVFVDVPDHRTEVLG
                     LELACADYLAEVPWILVERGGDICHELEEVGREYEADAIVVGSTHGLVGRLFGSVAGRL
                     AKRAQRPVVVIP"
     gene            20016..20330
                     /locus_tag="IE148_RS29455"
                     /old_locus_tag="GCM10010287_59500"
     CDS             20016..20330
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE148_RS29455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010287_59500"
                     /product="hypothetical protein"
                     /protein_id="WP_189366533.1"
                     /transl_table=11
                     /translation="MPRPAHAPVRPPEDDLLRWAALGCLLAPAVLLWRGAPFLTAAGVA
                     CGLAAVAAASRMLIRRSRRLAALPRPRHRDAGPRASAPAPSPGASAPLPTRGRAPRRTP
                     "
     misc_feature    20372..20386
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.16"
                     /tool="antismash"
     misc_feature    20525..20538
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.26"
                     /tool="antismash"
     gene            20726..21961
                     /locus_tag="IE148_RS29460"
                     /old_locus_tag="GCM10010287_59510"
     CDS             20726..21961
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019525175.1"
                     /locus_tag="IE148_RS29460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_59510"
                     /product="GlxA family transcriptional regulator"
                     /protein_id="WP_086704860.1"
                     /transl_table=11
                     /translation="MSHDSTAAPENAARKLSGRRRKEIVAVLLFSGGPIFESSIPLSVF
                     GVDRQDAGVPRYRLLVCGGEEGPLRTTGGLELTAPHGLEAISRAGTVVVPAWRSITSPP
                     PDDALDALRRAHEEGARIVGLCTGAFVLAAAGLLDGRPATTHWMYAPTLAKRYPSVHVD
                     PRELFVDDGDVLTSAGTAAGIDLCLHIVRTDHGNEAAGALARRLVVPPRRSGGQERYLD
                     RSLPEEIGADPLAEVVAWALEHLHEQFDVETLAARAYMSRRTFDRRFRSLTGSAPLQWL
                     ITQRVLQAQRLLETSDYSVDEVAGRCGFRSPVALRGHFRRQLGSSPAAYRAAYRARRPQ
                     AERGQGDGTAQGAPTGGVPAGRPEPAGHSMPQQLHSDGGVPHQARRSAAAGALGSPLTA
                     SAPGVPGQRSAP"
     misc_feature    21398..21400
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    22058..22073
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.27"
                     /tool="antismash"
     gene            22105..22707
                     /gene="orn"
                     /locus_tag="IE148_RS29465"
                     /old_locus_tag="GCM10010287_59520"
     CDS             22105..22707
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0000175 - 3'-5'-RNA exonuclease activity
                     [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="orn"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003990443.1"
                     /locus_tag="IE148_RS29465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_59520"
                     /product="oligoribonuclease"
                     /protein_id="WP_086704861.1"
                     /transl_table=11
                     /translation="MNDRMVWIDCEMTGLSLSDDALIEVAALVTDSELNVLGEGVDIVV
                     RPPERALETMPEVVRAMHTASGLLDELPNGTTLEDAEQRVLAYIKEHVKEPGKAPLCGN
                     SVGTDRGFLLRDMPTLESYLHYRIVDVSSIKELARRWYPRAYFNSPEKNGNHRALADIR
                     ESIAELRYYREAVFVPQPGPDSDTAKKIAAKHVLPAH"
     misc_feature    complement(22763..22781)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.23"
                     /tool="antismash"
     misc_feature    complement(22771..22782)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.87"
                     /tool="antismash"
     tRNA            22827..22899
                     /anticodon=(pos:46417..46419,aa:His,seq:gtg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="IE148_RS29470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="GCM10010287_t00700"
                     /product="tRNA-His"
     gene            22827..22899
                     /locus_tag="IE148_RS29470"
                     /old_locus_tag="GCM10010287_t00700"
     misc_feature    complement(22914..22929)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.13"
                     /tool="antismash"
     misc_feature    23268..23287
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: medium, score: 24.12"
                     /tool="antismash"
     gene            23310..24524
                     /locus_tag="IE148_RS29475"
                     /old_locus_tag="GCM10010287_59530"
     CDS             23310..24524
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014047574.1"
                     /locus_tag="IE148_RS29475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_59530"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_086704862.1"
                     /transl_table=11
                     /translation="MANDDLGRTLRRLRRLASLTQEELASRSGVSVDVIRQLEQRRKHS
                     ARLPTLHALANGLGVELTTLLGDPPAVSSSGENDGPQFVAVRRAIMPALWGPEPPPPGP
                     DFTLDGLRGQIADGWTQYHAAEFDTVMKAIPDLISDARSAAASGSEDERGAGYAALGKV
                     LQLAGHVAVRMGKTDLALISLERAIDAAEQSSDPLLLPMIVNSTAWTYQRQGRLADALG
                     IALRAADNMADLGLTGTADGLKVWGGLTMSAATSAARSGDYERAAAMMETAEKEAARVS
                     KMPDGGDKRMVSVFSPSSVRVERVRLAVQYGHPRDALALAKGMRLSKDTPPSWRTWLLL
                     DVARAHADIGDAAGAVKTLESLRRVAPAWMQHHTLAVAIVRDLWALPHHPPGLGALADF
                     LGVSE"
     gene            24646..25023
                     /locus_tag="IE148_RS29480"
                     /old_locus_tag="GCM10010287_59540"
     CDS             24646..25023
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009190795.1"
                     /locus_tag="IE148_RS29480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_59540"
                     /product="hypothetical protein"
                     /protein_id="WP_189366534.1"
                     /transl_table=11
                     /translation="MTHRTAAAPPPSGSPRAALLEVAADVLAVLLLPSPEDATEDQLRG
                     AGCIWCETGPLNAETAIDFGEQKTLAGESWFPRACLRCAAAWAHRGLFEHAPLCEQCTD
                     EVSRCEIGLALYRLIRQGRRP"
     misc_feature    24700..24702
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    24736..24738
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            25131..25625
                     /locus_tag="IE148_RS29485"
                     /old_locus_tag="GCM10010287_59550"
     CDS             25131..25625
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018565112.1"
                     /locus_tag="IE148_RS29485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_59550"
                     /product="hypothetical protein"
                     /protein_id="WP_189366535.1"
                     /transl_table=11
                     /translation="MDPPDNPALPVLARMLIADERFASCRSTVMDANPGMSEEMAGRIV
                     EEGIKFVAACSRNPGTGLAPSRIVDEGWHALILHTAMYAELCTNLGGMFVHHYPGYDPT
                     NYDPSILDRTREAIAALGWEADPELWGPPFGETLVPVAAKCQHAPDCTVRPMPKPEPPV
                     V"
     gene            25655..25783
                     /locus_tag="IE148_RS34130"
                     /old_locus_tag="GCM10010287_59560"
     CDS             25655..25783
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018565113.1"
                     /locus_tag="IE148_RS34130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_59560"
                     /product="hypothetical protein"
                     /protein_id="WP_281397514.1"
                     /transl_table=11
                     /translation="MSEWIDPRYAELVAVWKRAQQPESRSPQEPQPVRGFVVLRKP"
     gene            complement(25860..26075)
                     /locus_tag="IE148_RS34135"
     CDS             complement(25860..26075)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024835.5"
                     /locus_tag="IE148_RS34135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_189366546.1"
                     /transl_table=11
                     /translation="MSGRGGRPRPAGNAGSRVREHHNLTQLEVCGRSGIDAVSYSRIEQ
                     GHSSPLLDTLIRIADAIDVPLADLVR"
     gene            complement(26082..27137)
                     /locus_tag="IE148_RS29495"
                     /old_locus_tag="GCM10010287_59580"
     CDS             complement(26082..27137)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015660189.1"
                     /locus_tag="IE148_RS29495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_59580"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_048457752.1"
                     /transl_table=11
                     /translation="MASHGVRGRSGGRPTLEEVAARAGVGRGTVSRVINGSPRVSEATR
                     AAVEAAVAELGYVPNTAARALAANRTDAIALVVPEPETRFFTEPYFSDMLRGVGAALSD
                     TEMQLLLIFAGSDRERQRLAQYLAAHRVDGVLLVSVHADDPLPDMLSQLEIPAVISGPR
                     SADETLTSVDSDNYGGARQAVEHLISRGRRTIAHITGRLDVYGAERRVDGYRDALREAG
                     HPVDELLIEPGDFSEDGGRRAMEALLERRPDLDAVFAASDVTAAGARQALREAGRRIPD
                     DVALVGYDDSAIARHMEPPLTSVRQPIEEMGRAMTDLLLAEVADRRPSATRELERRQMV
                     LATELVERASS"
     misc_feature    27260..27277
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.75"
                     /tool="antismash"
     misc_feature    complement(27263..27280)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.35"
                     /tool="antismash"
     misc_feature    complement(27349..27363)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 28.65"
                     /tool="antismash"
     misc_feature    27350..27364
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 28.65"
                     /tool="antismash"
     gene            27480..28838
                     /locus_tag="IE148_RS29500"
                     /old_locus_tag="GCM10010287_59590"
     CDS             27480..28838
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006131559.1"
                     /locus_tag="IE148_RS29500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_59590"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_086705070.1"
                     /transl_table=11
                     /translation="MRARTLPLTRQRSGGGQPFARKALAVAAVVSLGTGLLAGCADDGG
                     DDSSGGSSSGEGKTTITLGLFGTMGFKEAGLYAEYEKLNPDIKIQENVVERNENYYPAL
                     VNHLTTNSGLMDVQAVEVANIAEVVGTQADKFTDMSKVEGVKKEGWLPWKWEQATTKDG
                     QTIGLGTDVGPMAICYRKDLFEKAGLPSDRAEVGKLWAGDWNKFIATGEKYKKAAGKDT
                     FFMDSPGGLLNAVLSSEKEKFYDASGEVIYKTNPAVKDAFDLTAEAAEKGLVQSQTQFQ
                     PAWDTTIANSKFATVACPPWMLGYIKGKSKPDAAGKWDVAVAPKSGNWGGSFLGVPKSG
                     KNVEEAQKLVAWLTAPEQQAKLFKVQGSFPSAPAAYDSPEVTGATNEMTGDAPIGEIFS
                     EAAKQIPVQVIGPKDQIIQQGLTDNGVILVTKGKSADEAWETATKTIDNNLDQ"
ORIGIN
        1 ctgggagtgg ggttcgcggg gctcgccgaa gcggccgtag ggcggctcgt cgacgtagcg
       61 caggtcgacg gcggcgcgtg cctcgaggaa gcggtcgacg acctcggggt cgaggtgggc
      121 gtagccgcgc aggcgttcct ccgaggtggg gagcgcgtcc gggtccgggg acgccggcat
      181 cgggtcctgg tggtccaggc cctcctcgta cgtctggaag gacgcggaga ggtggaagat
      241 cggcttgccg tgctggaccg cgaccacccg ccgggtggtg aacgagcggc cgtcgcggat
      301 ccggtcgacg gtgtagacga tcggcgcgcc ggggtcgccg aggcgcagga agtacgcgtg
      361 cagggaatgg gcgggccggt cctcggggac ggtccgcccg gccgcgacca gcgcctgcgc
      421 cgcgacctgc ccgccgaaga cgcgggggac gacggcgctg cgcgagctgc cgcggaagat
      481 gttctcctcg atctgctcga ggtcgagcag atcgaggagt tcctgaagag cctgactcat
      541 ggaatcagtt gtatacggca gggatttccg ggaccttaca gacccatgtc cttggcgatg
      601 atcgacttca tgatctcgct ggtgccgccg tagatccggt tgacccggtt gtccgcgtac
      661 aggcgggcga tcgggtactc gttcatgtag ccgtagccgc cgtgcagctg gaggcagcgg
      721 tcgatgacgc ggtgggcgac ctcggtgcag aacagcttgg cgctggcggc ctccgcgggg
      781 gtgagctcgc cggcgtccag ggcctcggtg gcgcggtcgg cgacggcctc ggcggcgtcc
      841 acctcggcct ggcaggcggc cagctcgaac ttggtgttct ggaagtgcgc gaccggcttg
      901 ccgaagacgg tgcgctcctg cacgtactgc ttggcgaacc ggacggcggc cttggcctgg
      961 gcgtaggcgc cgaaggcgat gccccagcgc tcggaggcca ggttgtggcc gaggtagtag
     1021 aagcccttgt tctcctcgcc gaggaggtcc tcgacgggga ccttgacgtc gacgaacgcc
     1081 agctcggcgg tgtcggaggt cttcaggccg agcttgtcga gcttgcggcc gaccgagtag
     1141 ccctcggact tggtgtcgac ggcgaacagg gagatgccgt gacggcggtc ctcggccgtg
     1201 ggggccgcgg tgcgggcgca gacgatcacc ttgtcggcgt gcacgccgcc ggtgatgaag
     1261 gtcttggcgc cgttgaggac gtagtgggtg ccgtcctcgc tcagcttggc ggtggtcttc
     1321 atgcccgcga ggtcggagcc ggtgcccggc tcggtcatcg cgatggccca catctcctcg
     1381 ccggagacga acttcggcag gaagcgcttc ttctgctcgt ccgtggccag catcttgatg
     1441 tagggcaggg cgagcagcac gtgcacgccg gagccgccga actggacgcc cgcgcgggcg
     1501 gtctcctcgt agaggacggc ctcgaacttg tgggtgtcca tgcccgcgcc gccgtactcc
     1561 tccggcacgc tgatgccgaa gatgcccagc tcaccgagct tgtagtagaa gtcgcggggc
     1621 gcctggcccg ccgcgaacca ctcgtcgtag acggggacga cctcggcctc gatgaaggcg
     1681 cggatggtct cccggaacgc ctcgtgatcc tcgttgaaaa ccgtacggcg cactgtccgc
     1741 caccccaatc cctgcgcctg aaccggcgcc gctctcgcgt acctgggcgc tcgccgtcgg
     1801 ggttcctcaa ttgatggctg cggcccgcat ggctaagcgc ttgctcagaa caaggtaccg
     1861 gcgagtatcc acagccgtcc agaccggacg ccccgtaacg ctcgtcactc cggggggccc
     1921 tgaaggcggc cccgcggaga ctcaggcgcc cgccgccgcg aacgcccccc gcgccatccg
     1981 gtgcagcagc tccgccgtgc ccgcgcggtc cgggagggag cccgggcggg tgaggtgggg
     2041 cgtggagttg aggaggccga agaccgagtg gaccgccgag cgggccgcgg gctcggtgag
     2101 gtccgggtag aggcggcgca ccacggccac ccacagctcg acgtactgcc gctggagctg
     2161 gcgcacgagc ttgcggtcgg cgtcccggag gcggtccagc tcacggtcgt gcagggtgat
     2221 gagcgggcgg tcgtcgagcg cgaagtcgat gtgcccctcg atcagcgagt cgaggaccgc
     2281 cccgggagcc accccgcccg ccccgttcgc ctcggcgagc cgccgcttcg cacccgtcag
     2341 cagcgactcg ctgatgccga ccagcagctc cgccagcatc gcatccttgc ccgcgaagtg
     2401 ccggtagagc ccgggtccgc tgatgccgac ggcggcgcct atctcgtcga caccgacccc
     2461 gtggaagccc cgttcggcga agagccgcgc ggcctccttg aggatctgct cgcggcgggt
     2521 gggggcgtcg gttctggtgg ccatgaagac aattctagac agggaggtta gcggtcgtta
     2581 acctggagga aatgcgttaa cgctcattaa caaggtgagg ggacccgcag gatgcatgag
     2641 gcaccggagc ttcacagcgc ggctgatccc gcgtcggagg cctttcgggc caacgaggag
     2701 gcgcaccgcg ccctcgtcga ggagctgcgc ggcaagctgg ccgcggcggc gttcggcggc
     2761 ggcgagcggg cgcgcgcccg tcacaccgcg cgcgggaaac tgctcccgcg cgaccgggtg
     2821 gacaccctcc tggaccccgg ttcgcccttc ctggagctgg ccccgctggc cgccgacggg
     2881 atgtacgacg ggcaggcgcc ggcggccggg gtgatcgccg ggatcggccg ggtcgcgggc
     2941 cgcgagtgcg tggtcgtcgc caacgacgcc acggtcaagg gcggcacgta ctacccgatg
     3001 accgtgaaga agcacctgcg cgcacaggag gtggccctgg acaaccggct gccctgcgtc
     3061 tacctggtgg actccggcgg ggcgttcctg ccgatgcagg acgaggtctt cccggaccgg
     3121 gaccacttcg gccgcatctt ctacaaccag gcccgcatgt ccggcgccgg catcccgcag
     3181 atcgcggcgg tgctcggctc ctgcaccgcc ggcggcgcgt acgtgcccgc catgagcgac
     3241 gaggcggtga tcgtgcgggg ccagggcacg atcttcctcg gcggcccgcc gctggtgaag
     3301 gcggccaccg gcgaggtggt cacggcggag gagctgggcg gcggcgaggt ccactcgcgg
     3361 gtgtccgggg tgaccgacca ccttgccgag gacgacgcgc acgcgctgag gatcgtgcgc
     3421 cagatcgtct ccacgctgcc cgggcgcggc gagctgccct ggcgggtgga gccggtcgcc
     3481 gagcccaagg tggacccggc ggggctgtac ggcgcggtgc cggtggactc ccgcaccccc
     3541 tacgacgtcc gcgagatcat cgcccggatc accgacggct cccggttcgc cgagttcaag
     3601 gcggagtacg ggcagaccct ggtcaccggc ttcgcgcaca tccacggcca cccggtgggg
     3661 atcgtcgcca acaacggcat cctgttctcc gagtcggccc agaagggcgc ccacttcatc
     3721 gagctgtgcg accagcgcgg catcccgctg ctgttcctgc agaacatctc gggcttcatg
     3781 gtcggcaagg actacgaggc gggcggcatc gccaagcacg gcgccaagat ggtcacggcc
     3841 gtcgcctgca cgcgggtgcc gaagctgacc gtcgtggtcg gcggctccta cggcgcgggc
     3901 aactattcga tgtgcggccg ggcctactcc ccccgcttcc tgtggatgtg gccgaacgcc
     3961 aagatctcgg tgatgggcgg cgagcaggcc gcctcggtgc tcgcgaccgt caagcgggac
     4021 cagctggagg cgcgcggcga ggactggccc gcggacgagg aagaggcctt caaggccccg
     4081 gtccgcgccc agtacgagcg ccaggggaac gcctactacg cgacggcccg cctctgggac
     4141 gacggcgtga tcgacccgat ggacacccgg caggtgctgg ggctggccct gaccgcgtgc
     4201 gccaacgcgc ccctgggtga cccccagttc ggcgtcttcc ggatgtgagg ggacccctga
     4261 cgatgactga tcagatgttc gacacggtgc tggtggcgaa ccggggcgag atcgccgtcc
     4321 gtgtcgtgcg cacgctgcgg tcgctgggcg tgcgctcggt ggcggtgtac tccgacgcgg
     4381 acgcgggcgc ccggcacgtc cgggaggccg acacggcggt gcggatcggc ccggcgccgg
     4441 ccgcggagag ctacctgtcg gcggaccggc tgctggaggc tgccgcccgc accggcgcgc
     4501 gtgcggtgca cccggggtac ggcttcctcg cggagaacgc ggagttcgcg cgggcctgcg
     4561 aggcggcggg actggcgttc atcggcccgc ccgcggacgc catcgccctg atgggcgaca
     4621 agatccgcgc caaggagacg gtgaaggcgg ccggggtgcc ggtggtgccc ggctccagcg
     4681 gcagcgggct gacggacgag cagctcgtcg acgcggcccg ggagatcggc atgcctgtgc
     4741 tgctgaagcc gtcggcgggc ggcggcggca agggcatgcg gctggtgcgg gacgagacgc
     4801 gtcttgcgga cgagatcgcc gccgcccggc gtgaggcccg cgcctccttc ggcgacgaca
     4861 cgctgctggt ggagcggtgg atcgaccggc cccggcacat cgagatccag gtgctggccg
     4921 acggccacgg caacgtggtg cacctgggcg agcgcgagtg ctcgctccag cggcggcacc
     4981 agaagatcgt cgaagaggcg cccagtgtcc tcctcgacga ccgaacgcgg gccgcgatgg
     5041 gcgaggcggc cgtgcaggcg gcccgctcct gcggctaccg gggcgcgggc acggtcgagt
     5101 tcatcgtccc gggcgacgac ccgtcggcgt actacttcat ggagatgaac acccggctcc
     5161 aggtggagca cccggtcacc gagctgatca cggggctcga cctggtggag tggcagttgc
     5221 gggtcgcggc gggcgagcgg ctggcgttcg ggcaggacga cgtacggctc accgggcacg
     5281 cggtggaggc gcggctgtgc gccgaggacc ccgcgcgcgg tttcctgccc tccggcggca
     5341 cggtgctgcg gctgcgcgag ccgcagggcg acggcgtgcg caccgactcc gggctgtccg
     5401 agggcacgga ggtcggcagc ctctacgacc cgatgctgtc caaggtcatc gcctacggcc
     5461 ccgaccgggc gaccgcgctg cgcaagctga gggcggcgct cgcggagacg gtgacactgg
     5521 gcgtgcagac caacgcgggc ttcctgcggc ggctgctggc gcacccggcg gtcgtgtcgg
     5581 gcgagctgga caccggtctg gtggagcggg aggcggactc cctggtcggc ggcgaggtgc
     5641 cggccgaggt gtacgcggcg gcggcgctgc tgcgccaggc cgccctcgaa cccgccgcgg
     5701 cgcccggctg gcgtgacccg ttcgacgccg ccgacggctg gcggatgggc ggtggccggg
     5761 cctggacggc gcaccatctg cgggcggcgg gccacgaccc ggtgaccgtg cgggtgcggg
     5821 ccgcggccga cggcggcacg gagctgctgc tgcccggcgc ggacaccccg gtgcgggcgt
     5881 ccgcggggcc gctggagggg caccggttca cctgcgcgct cgacggcgtc gcgtacacct
     5941 tcgccgctct gccggacggc acctggctgg gccgggacgg cgacgcctgg caggtgcggg
     6001 accacgaccc ggtcgccgcg tccctcaccc gggcgggtca ggcgggcgcc gactcgctga
     6061 ccgcgccgat gccgggcacg gtgacggtgg tgaaggtcgc cgtcggcgac gaggtggacg
     6121 cgggccagag cctgctggtg gtggaggcga tgaagatgga gcacgtcatc tccgccccgc
     6181 acgccggcac ggtcacggag ctggacgtgt ccccgggcac gacggtcgcc atggaccagg
     6241 tgctcgcggt catcgcgccc gtggagaccg cggcaccggc ggaaggggag acggcatgaa
     6301 cgcgagcgag ctgggcctgc ccatggccgt gccggccgag gggctgcccg cgcgggtgcg
     6361 gatccacgag gtgggcgccc gcgacggcct gcagaacgag aaggcgaccg tgccgacggc
     6421 cgtgaaggcg gagttcgtcc gccggctggc cggcacgggg ctgaccacga tcgaggcgac
     6481 gagcttcgtg cacccgaagt gggtgcccca gctcgcggac gccgaggagc tgtacccggc
     6541 ggtctcggac ctgccggtcg agctgccggt gctggtgccc aacgagcgcg gccttgaccg
     6601 cgcactggcg ctgggcgccc gccgggtggc ggtgttcgcc agcgccacgg agtccttcgc
     6661 caaggccaac ctgaaccgca cggtggacga ggcgctggcc atgttcgagc cggtggtggc
     6721 ccgcgcgaag gagcaggacg tccatgtgcg cggctatctg tcgatgtgct tcggcgaccc
     6781 ctgggagggc gcggtcccgg tcccccaggt ggtgcgggtg tgccgggcgc tgctcgacat
     6841 gggctgcgac gagctgagcc tcggcgacac gatcggggtg gcgaccccgg gtcatgtgac
     6901 ggccctgatc gccgcgctca cggaggcggg cgtgcccgtc cccgcgctgg gcgtgcactt
     6961 ccacgacacc tacggccagg ctctgtccaa caccctggcc gcgctccagc agggcgtcgc
     7021 cacggtcgac gcctcggccg gcgggctggg cggctgcccg tacgcgaagt ccgccaccgg
     7081 caatctcgcc accgaagacc tcgtgtggat gctgcggggc ctcggcatcg acaccggcgt
     7141 cgatctcggc cgtctggtcg ccacaagcgt ctggatggcc gcccacctgg gccgacccag
     7201 cccgtcccgc accgtacgag ccctctccca ccaggagcag tgacgacatg gaccacaagc
     7261 tctcccccga actcgaggaa ctccgccgca cggtcgagga gttcgcacac gacgtggtgg
     7321 cgccgaagat cggcgacttc tacgagcggc acgagttccc gtacgagatc gtgcgggaga
     7381 tgggccgcat gggcctgttc ggtctgccgt tcccggagga gtacggcggc atgggcggcg
     7441 actacttcgc gctcggcgtc gccctggagg aactggcccg ggtggactcc tcggtggcca
     7501 tcaccctgga ggcgggcgtc tcgctgggcg cgatgccgct gcacctgttc ggcacggagg
     7561 agcagaagcg tgagtggctg ccccggctgt gctcggggga gatactcggc gcgttcggcc
     7621 tcaccgagcc ggacggcggc agcgacgcgg gcgcgacccg cacgacggcc cgtctcgacg
     7681 aggcgacggg cgagtgggtg atcaacggca ccaagtgctt catcaccaat tccggcacgg
     7741 acatcaccgg tctggtcacc gtcaccgccg tcaccggccg ggggcccgac ggcaagccgc
     7801 ggatctccgc gatcatcgtg ccgtccggca ccccgggctt cacggtggcg gcgccgtact
     7861 cgaaggtcgg ctggaacgcc tcggacaccc gtgagctgtc cttccaggac gtacgcgtcc
     7921 cggcggccaa cctgctgggc gaggagggcc gcggctacgc gcagttcctg cgcatcctcg
     7981 acgagggccg catcgccatc gcggcgctgg ccacggggct cgcgcagggc tgtgtggacg
     8041 agtcggtgaa gtacgccagg gagcggcacg cgttcgggcg tccgatcgga gccaaccagg
     8101 cgatccagtt caagatcgcc gacatggaga tgaaggcgca cacggcgcgg ctggcgtggc
     8161 gggacgcggc gagccggctg gtggcgggcg agccgttcaa gaaggaggcg gcgctggcca
     8221 agctctactc ctccacggtg gccgtggaca acgcccgcga cgccacgcag gtccacggcg
     8281 gctacggctt catgaacgag tacccggtgg cccggatgtg gcgcgactcc aagatcctgg
     8341 agatcggcga gggcaccagc gaggtccagc ggatgctcat cgcgcgggag ttgggcctgg
     8401 cgggctgagc ctgccccttc tcagtgacgg cccgcgccgc tcccggcgcg ggccgtcgcc
     8461 gtgccgccgg gtgacccgga tcacggggtg gaaccggcgc atgccggaca tggatgcggg
     8521 acgccctctg gacagatcat ttggttaggc taacctaacg ctgtttgtac atcggtcccg
     8581 tacgcacgaa agcagaccct tccatgccga acgccacaac cgcccgcctc tcccgtcgtg
     8641 gactgctcgc cgccggcggc gccctgggcc tcggtgccgt gctcaccgcc tgcggggacg
     8701 acgacgcgaa ggacggcggc gcggacacga agggcgccgc caagtccggc ccctggagct
     8761 tcaaggacga ccgcggcacc acggtgaagc tgggcgaggc gccgaagaac atcgtcgcgt
     8821 tcacgggcgt ggccgccgcg ctgtacgact acggcatcga ggtcaagggc gtgttcggcc
     8881 cgaccacgac caaggacggc aaggccgacg tccaggccgg cgacatggac gtcagcaagg
     8941 tgacggtcct gggcaacgtc tgggaccagt tcaacgtcga gaagtacgcg gccctcgcgc
     9001 ccgacgtgct catctccacg atgttcgacg acgccggcac cctctggtac gtccccgagg
     9061 cgtccaagga caagatcgcc aagctcgccc ccagcgtcgg catctccgtg ttcgaccgtc
     9121 agctcaccgc cccgctccag cggatgtggg agctggccga gtcgctcggc gccgacatga
     9181 cggccgcgaa ggtcaccgag gccaagaagc ggttcgaggc ggcctcggag cggctgcgca
     9241 aggccgccaa ggccaagccc gagatcaagg tgctggtcgg ctccgcgagc cctgagctgt
     9301 tctacgtctc gggcagcaac ctctcgatcg acctggagta cttcaaggcc ctcggtgtga
     9361 acttcgtgga gccgacggag gcggccaaga aggccaccgg cggatggttc gagagcctga
     9421 gctgggagaa cgtcgacaag cacaaggccg acgtgatcat gatggacgac cgctcctcgg
     9481 ccatccagcc cgccgacatc accgaggcga cctggaagca gctgcccgcc gtcaaggccg
     9541 gccaggtcat cgcccgttcc accgagccga tcctgtccta cgacaagtgc gtggcgccgg
     9601 tggaggcgct cgccgaggcc atcgagaagg ccaggaaggt cagctgaccc cctggcaagg
     9661 cccctctcac aggccccctc gcaaggttca gccgcccccg actcgcagga gtacgccgtg
     9721 acgactgccg tggccgcccc gttccgtttc ttcgcccttc aggtcgccgg gacgcggcgg
     9781 ctcggcccgt cgctcgtgcg ggtcaccttc accgggccgg agctgcgcga cttccgctcc
     9841 gacgggcgtg accagtccct gtcgctgttc ctgccccacc cggggcagga cgcgccggtc
     9901 gtgccgttgg agctgggtga cgactggtgg cagggctggc gcgaactgcc cgacgacgta
     9961 cgggcggtga tgcgctcgta cacgctgcgg gcgctgcgcg cggacgccct gggccggacc
    10021 gccgagatcg acgtcgactt cgtgctgcac ggcgtcggcg aggcgggccc gtccgccgag
    10081 gccggtcccg cgtcccgctg ggccgcccgc gccgccgcgg gcgaccgggt gctgctgctc
    10141 ggccccgcga tcgcggacaa ccgcgcgatc cgcttccgcc ctcccgagga cgcctcgacg
    10201 gtgctgctgt gggcggacga gaccgccctg cccgccgcgg ccgccgtcct ggagtccctc
    10261 ccggccggca tccgcgccca ggtctggctc gaggtgccgc acgccgggga cgtccaggag
    10321 ctgccgaccg cggcggacgc ggagatcacc tggttcgtgc gggagggtgt cgccgcaccg
    10381 gagaccccga cggccctgga cgccgtccgg cagaccgccc tcccctcccc cgagcgtgcc
    10441 tacgtgtgga tcgccgggga gtccggccgg gtcaagcagc tgcgccggca cttcgtccgt
    10501 gagcgtgggg tcgaccgccg gcgggtgacg ttcgtgggct actggcggcg tggcctgacg
    10561 gaggaacagc tccgcgaaca ggtctgagcc acaagcgagt tgacgctccg cagcgtcccg
    10621 ccgaggacgt gacgacggtc acgaaggaag cgggaatacc ctcggaaaag tttggttagg
    10681 ctaacctaag ttcaaccgca ctggacctct ccccgcaccg gaccgtcccc accggaggac
    10741 ccccacatgc gctcgcacct gctcaacgac accaccgcgg agcactaccg acgctccgtg
    10801 accgaaggag tcgagcgggt ggccgccaaa ctcgccgcca ccgaccggcc gttcaccggc
    10861 gtcacggccg acgacctcgc cccgcgcatc gacgcgatcg acctcgaccg gccgctgcgc
    10921 gacaccaccg cggcgctgga cgagctggag gacgtctacc tcagggacgc ggtctacttc
    10981 caccaccccc gctacctcgc ccacctcaac tgtccggtcg tcatcccggc cgtgctcggc
    11041 gaggcggtgc tctccgccgt caactcctcc ctggacacct gggaccagtc ggccggcggc
    11101 accctgatcg agcggaaact gatcgactgg acggccgccc gcatcggcct cggtcccgcc
    11161 gccgacggcg tgttcacctc aggcggcacc cagtccaacc tccaggcgct gctgctggcg
    11221 cgggaggaga ccaagacgga ggagctgacg aagctgcgcg tcttcgcctc cgaggtcagc
    11281 cacttcagcg tgcagaagtc cgcgaagctg ctcggcctcg gcccggacgc cgtggtggtg
    11341 gtccccgtcg accacgacaa gcggatgcag accgtcgccc tcgcccacga actggagcgc
    11401 tgcgccgagg cggggctgat cccgatggcg gtcgtcgcca ccgccggcac caccgacttc
    11461 ggctcgatcg acccgctgcc ggagatcgcc ggcctgtgcg agcagtacgg cgcctggatg
    11521 cacgtggacg ccgcctacgg ctgcggactg ctcgcctccc gcaagtaccg gcaccgcatc
    11581 gacggcatcg agcgcgccga ctccgtcacc gtcgactacc acaagtcctt cttccagccg
    11641 gtcagttcct cggccgtgct ggtgcgcgac gcggccacgc tgcggcacgc cacctatcac
    11701 gcggagtacc tcaacccgcg ccgcatggtg accgagcgca tccccaacca ggtcgacaag
    11761 tccctccaga ccacccgccg cttcgacgcg ctgaaactgt ggatgacgct gcgcgtgatg
    11821 ggtgccgacg gcatcggcgc gctcttcgac gaggtgtgcg acctcgccgc cgagggctgg
    11881 aagctgctgg ccgccgaccc ccggttcgac gtggtggtcg agccgagcct ctccaccctg
    11941 gtcttccgct acatcccggc cgccgtcacc gacccgggcg agatcgaccg cgccaacctg
    12001 tacgcccgca aggccctgtt cgcctccggc gacgcggtgg tcgcgggcac caaggtgtcc
    12061 gggcgccact acctgaagtt caccctgctc aaccccgaga ccacgacggc cgacatcacg
    12121 gccgtcctcg acctgatcgc cggccacgcc gagcagtacc tgggagagtc ccttgaccgc
    12181 gcttgctgac accacgaaac cgacctacga cttcgtgggc atcgggctgg gcccgttcaa
    12241 ccttgggctg gcctgcctga ccgagcccgt cgacgaactc gccggggtct tcctggagtc
    12301 caagccggac ttcgcgtggc acgcggggat gttcctcgac ggcgcgcacc tgcagacgcc
    12361 gttcatgtcg gacctggtca ccctcgccga cccgacctcc ccctactcct tcctcaacta
    12421 cctgaaggag aagggccggc tgtactcgtt ctacatccgg gagaacttct acccgctgcg
    12481 cgtcgagtac gacgactact gccgctgggc cgccgcacag ctgagcagca tccgcttcgg
    12541 caccaccgtc accgaggtca cgtgggacga gacggccgag gtgtacgtcg tggccacgtc
    12601 caccggtacg acctaccgcg gccggcacct ggtgctcggc accggcaccg tgccgttcgt
    12661 gcccgaggcg tgccgggggc tggagggcgg cctcttccac aacgcgcagt acatgcggcg
    12721 caaggcggag ctgctggaga agaagtcggt cacgatcgtg ggcagcgggc agtccgccgc
    12781 cgagatctac tacgagctgc tctccgggat cgacgcccac ggctatcagc tcaactgggt
    12841 cacccgctcc ccgcggttct tcccgctgga gtacaccaag ctgaccctgg agatgacgtc
    12901 cccggactac atcgactact tccgcgcgct gcccgaggac acccgctacc gcctggagaa
    12961 gcagcagaag ggcctgttca agggcatcaa ctcggacctg atcgacgcga tcttcgacct
    13021 gctgtaccag aagaacgtgg agagcggcgg ccgcggcgtg cccacccggc tgctcaccaa
    13081 ctcctcgctc accaccgccc ggtaccagga cggcacctac acgctcggct tccgccagga
    13141 cgagcagggc aaggacttcg agatcgccac cgagggcctg gtgctggcca ccggctacca
    13201 ctacgagcag cccgccttcc tggagccggt gcgtgaccgg ctgcgcttcg acggccacgg
    13261 ccggttcgac gtcgcccgca actacgcgat cgacgtcacc gggcgcggcg tgttcctgca
    13321 gaacgcgggc gtgcacacgc acagcatcac cagccccgac ctgggcatgg gcgcctaccg
    13381 caacgcctcg atcgtccgcg agctgctggg caccgagtac tacccggtcg agaagagcat
    13441 cgccttccag gagttcgccg tatgagcacc atcggtacgt tcacgatccg cccgctcgac
    13501 ccggagaagg acgcggagct gctgcaccgc tgggtgacgc atcccaaggc cgcgttctgg
    13561 atgatgcagg acgcgaggct cgaggacgtc gagcgcgagt acatgcgcat cgccgcccac
    13621 gagcaccacc acgcctacct gggcctgcac gacggcgagc ccgccttcct gatggagaag
    13681 tacgaccccc ggcacgtcga actcgtcggg ctctacgagc cagagcccgg tgacgtcggc
    13741 atgcacttcc tggtcgcccc caccgaccgc cccgtccacg gcttcacccg cgccgtcatc
    13801 accgccgtga tggaggagct gttcgccgac ccggccaccc gccgggtcgt ggtggagccg
    13861 gacgtcggca acaaggccgt gcacgccctg aacgaggccg tgggctttga acccgagcgc
    13921 gagatcgaca agccggagaa gcgcgcgctg ctgagcttct gcacgcgtga acagttcgag
    13981 gccgcccgag gagcttccgc atgaccctgt ccgacgccgt ggcgcacctg tccccccacc
    14041 gctgggcgcg ggccaaccgt ctgctgatcc gcaaggcgct cgccgagttc gcgcacgagc
    14101 ggctcgtcac gccggagccg gccggcgacg gccggtacgt cgtccgcagc gacgacggcg
    14161 agacccgcta cacgttcacc gcgaagcttc gcggcctgga ccactggcag gtcgacgccg
    14221 gctcgatcac ccgtcatcgc gacggcgtcg aactcgagct cgccgcgctg gacttcttca
    14281 tcgagctgca gaagtccctg gggctgagcg acgaaatcct gccggtgtac ctggaggaga
    14341 tctcctccac cctctccggc acctgctaca agctgaccaa gccggaggtc acctcggccg
    14401 agctggtcga cgccgggttc caggcgatcg agaccggcat gaccgagggc cacccctgct
    14461 tcgtcgccaa caacggcagg ctcggcttcg gcgtccacga gtaccggcag tacgccccgg
    14521 aggccgcgaa cccggtgcgg ctggtgtggc tggccgccca ccgctcgcgg gccgcgttca
    14581 cggcgggcgt cggcatcgag tacgagtcgt tcgtccgcca ggagctgggc gaggagaccg
    14641 tcgaccggtt ccacgacgtc ctgcgcgcgc aggacctgga ccccgccgac tacctgctgg
    14701 tccccgtcca cccctggcag tggtggaaca agctgtccgt caccttcgcc gccgaggtcg
    14761 cccgccggca cctggtgctg ctgggcgagg gcgacgacga gtacctggcg cagcagtcca
    14821 tacgtacctt cttcaaccgc tcccatccgg agaagcacta cgtgaagacg gccctgtccg
    14881 tcctcaacat gggcttcatg aggggcctgt cggccgccta catggaggcc accccggcca
    14941 tcaacgactg gctggcccgc ctgatcgaca acgacccggt gctgcggtcc acgggactgt
    15001 cgatcatccg ggagcgcgcc gccgtggggt accggcacct ggagtacgag caggccaccg
    15061 accgctactc gccgtaccgc aagatgctgg cggcgctgtg gcgggagagc ccggtgacgt
    15121 ccctggagga cggcgagtcg ctcgccacca tggcgtccct ggtccacgtc gaccacgagg
    15181 gccggtcctt cgccgccgcc ctgatcgagc gctccgggct caccccggcc gagtggctgc
    15241 ggcgctacct gcgggcctac tacgtcccgc tgctgcacag cttctacgcc tacgacctgg
    15301 tgtacatgcc ccacggcgag aacgtcatcc tggtgctgga ggacggcgcc gtgaagcgcg
    15361 cggtctacaa ggacatcgcc gaggagatcg cggtgatgga cccggacgcg gtactgccgc
    15421 cggaggtgtc ccggatccgc gtcgaggtcc ccgacgacac caagctgctg tccatcttca
    15481 cggacgtctt cgactgtttc ttccgcttcc tcgcggcgaa cctcgccgag gagggcgttc
    15541 tcgacgagga cggcttctgg cggacggtcg cggaggtcac ccgtgagtac caggcgtcgg
    15601 tgccggagct gacggacaag ttcgcccggt acaacctgtt cgccccggag ttcgcgctgt
    15661 cctgcctgaa ccgcctccag ctgcgcgaca acaagcagat ggtcgacctg gcggacccct
    15721 cgggcgccct ccagctcgtg ggcaccctga agaaccccct ggcggccttc tgaccgcatc
    15781 ggacggacga gcccccggag tacggtcctc cgggggcttc gtcacaccct caggtgcgac
    15841 gtccatcagg ggcgcggggc tgtgccggca tgcggctcct ccgcgcgggc gcgcccggcc
    15901 cccacccacg gccgggcacc cgccctcccc agccacacct cctccaactc ccgcccccgc
    15961 cagggaacgt ggcgatggaa caatcccccc atggcggaaa tcatccagaa ggacggcacg
    16021 tggacgttcg acggcgaaac cctgcgcctg acccccggcc gcgacaagaa cgtcggcctg
    16081 ctccgccgca cgctgggtga actggcgttg ccgctggagg cgttggcggg cgtctccctg
    16141 gagcagggca agaagtcggg ccggctcagg ctgcggctgc gcgacggcgc cgacccgctg
    16201 ctgcacgcga cgggtggccg cctcaccgaa ccgcacgacc cgtaccagct caccgtcgag
    16261 tccgaccgct acggcgtcgc ggagtacttc acggaggagg tccgcaccgc gctgctgctg
    16321 gagcagatcc cctccggacc ggtgaccggc tatctgctgc ccggcccgcc cctgccgctg
    16381 tccgtgtcgg ccggggacgg cacggtgagc ttcgacgggg agcgggtccg gctggagtgg
    16441 aactggaaga cggaggacgc caaggccgcc gcgggacccc gcaccctggc ggtggccgac
    16501 ctggagggcg tggactggca gccggcggcc gggctggaga acggccatct gcgcttcctc
    16561 gtgcggcacg cccccaccaa ggtcccggcc aagtacgacc cgaacgcggt ggagctgtgg
    16621 gggttcaaga aggacccgct gatggcgctg gtggccgccg ccgtgcaggc ccgtctgccg
    16681 cacccgtcca cccctgccgc cccggccctg gagggcccgg gcgcccccga gaccgaccgg
    16741 cccgcgccgc ccggccccgc cgaggacgac cacgacgcgc tgctgcgccg actgcgggag
    16801 ctgggcgagc tgcaccggtc cgggatcctc accgacgagg agttcgccct cgccaagcag
    16861 gccgtcctga agcggatgta ggggccacct actccaccct gcccgaaatc gggcacgttt
    16921 cttgcgaaac ggccgtcggt acctcaggat catcgggtgc acgacgaact tgtcgatcat
    16981 ctgacgcggt ccacgcccct cagccggggc gaggcgctgc gtgtgatcca ggacgtgctc
    17041 gcctacttcg acgagacgac cgaggagtac gtccgtcgcc gccaccgcga gctccaggcc
    17101 cagggcctgg tgaacgcgac gatcttccaa cggatcgagg cggacctgag ataccgcgcg
    17161 gtggcgccgc ccgagctctc gctccggcag ctgcgccgca tcgtctacgg ctaggaacat
    17221 acctgtatgt gcggaatcgt cggttacatc ggcaggcgtg aggtcgcccc cctgctgctc
    17281 gagggcctcc agcgtctgga gtaccgcggc tacgactcgg cgggcatcgc cgtgacctcc
    17341 ccgaagacgg gcaccctgaa gacggtcaag gccaagggcc gggtgcgcga cctggaggcc
    17401 aaggtcccgg cgcgtttcaa gggcaccacc ggtatcgccc acacccgctg ggccacccac
    17461 ggcgccccgt ccgacgtgaa cgcccacccg cacctggacg ccgagggcaa ggtcgccgtc
    17521 gtccacaacg gcatcatcga caacgccggt gacctgcgcc gcaagctgga ggcggacggc
    17581 gtcgagttcc tctccgagac cgacaccgag gtcctcgtcc acctcatcgc ccgctcgcag
    17641 gccgagaagc tcgaggacaa ggtccgtgag acggtccgcc tgatcgaggg cacctacggc
    17701 atcgccgtgc tgcacgccga cttcccggac cgcatcgtcg tcgcccgcaa cggctcgccg
    17761 gtcgtcctcg gcatcggcga gaaggagatg ttcgtcgcct cggacatcgc cgcgctggtc
    17821 gcccacaccc gccagatagt caccctcgac gacggcgaga tggccaccct caaggccgac
    17881 gacttccgca cctacaccac ggagggcacg cggaccaccg ccgagcccac caccgtggag
    17941 tgggaggccg cctcctacga catgggcggc cacgacacct acatgcacaa ggagatccac
    18001 gagcaggccg aggccgtgga ccgcgtcctg cgcggccgga tcgacgaccg cttctccacc
    18061 gtgcacctgg gcggcctcaa cctggacgcc cgcgaggccc gccgcatccg ccgtgtgaag
    18121 atcctcggct gcggcacctc gtaccacgcc ggcatgatcg gcgcgcagat gatcgaggag
    18181 ctcgcgcgca tccccgccga cgccgagccg gcctccgagt tccgctaccg caacgcggtc
    18241 gtcgaccccg acaccctgta cgtcgcggtc tcccagtccg gtgagacgta cgacgtgctg
    18301 gccgccgtgc aggagctgaa gcgcaagggc gcccgggtcc tcggcgtggt caacgtggtg
    18361 ggctccgcga tcgcccgcga ggccgacggc ggcgtctacg tgcacgcggg accggaggtc
    18421 tgcgtcgtct ccaccaagtg cttcaccaac accacggtcg ccttcgcgct gctcgccctg
    18481 cacctgggcc gcacccgtga cctctccgtg cgcgacggca agcggatcat cgagggtctg
    18541 cgccgcctcc ccgcccagat cgccgagatg ctggagcagg aggagcagat caagaagctg
    18601 gcgctggagt acgccgaggc ccgctcgatg ctcttcatcg gccgcgtccg gggctacccg
    18661 gtggcccgcg aggcctccct gaagctcaag gaggtctcct acatccacgc cgaggcctac
    18721 ccggcctccg agctgaagca cggcccgctg gccctgatcg agccggccct cccgacggtc
    18781 gccatcgtcc cggacgacga cctgctggag aagaaccgcg cggccatgga ggagatcaag
    18841 gcccgcagcg gccggatcgt cgccgtggcg caccaggagc aggagaaggc ggaccacacg
    18901 atcgtggtcc ccaagaacga ggacgagctg gacccgatcc tcatgggcat ccccctccag
    18961 ctcctcgcct accacacggc cctggccctc ggccgggaca tcgacaagcc ccgcaacctg
    19021 gcgaagtcgg tcacggtcga ataggacgcc caaggggcgc ggggaactgc gcgatcagcc
    19081 cccacgcacc cgcacaggcc gtgcgaacag gaacgggccc ccatgtgttg ccactcaaca
    19141 catgggggcc cgcctcacgt catggaatga cgacaaccgg ccgctgcgcc cgcttcgcca
    19201 gcctccccgc gaccgacccg aaaagccgtc ccacaagccc gtgggtggaa cccacgacga
    19261 tcgcgtcggc ctcgtactcc cgccccacct cttcgagttc gtggcagatg tccccgcccc
    19321 gctcgacgag gatccacggc acctcggcca gatagtccgc acaggcgagc tccagcccca
    19381 gcacctccgt acggtggtcc gggacgtcca cgaagaccgg cggctcgcac cccgcccaca
    19441 ccgtggtggg cagccggttc gccacatgga cgatgatcag cccggagccg gagcggcgcg
    19501 ccatgccgat ggcgtacgcg agggctcgtt cactggacgt ggaaccgtcg aagccgacca
    19561 ccaccccgtg ccggaaggcg gggtcgcgcg catggcgcga ttcctccgcc gccaggggtt
    19621 cggacgccgt cggatcggcg accggccgct tgcggtccgc gggttcgaag aattcgtgac
    19681 cggccatggc tgtctcgggg ttgtgatcct tttatgggga cgacagtgtg cggcggagct
    19741 gtgtccggga agtgtcttcc caaccccata cccccaaggg tacggcggca cgcctccttg
    19801 gcccagatcc cgcgcgaacc gggaggcggg ttccccggag catgcacgag ggtccgccca
    19861 cgacgcaacg gttgctggcc tgtacaggcg gtttgcgggg tattcgcttg acatctgaac
    19921 catccgcacc gggcgcctcg cacggtgacc gacgggcggc ccgcacgttg ggatggtgga
    19981 accacgacga ctcccccacg acaggaagcg ccccgatgcc ccgccccgcc cacgcccccg
    20041 tccggccccc tgaggacgat ctcctgcgct gggcggcgct cgggtgcctg ctggcccccg
    20101 cggtcctcct gtggcgcggc gcgcccttcc tcacagcggc cggcgtggcc tgcggcctgg
    20161 cggccgtcgc ggccgcgtcc cgcatgctga tccgccgctc ccggcgcctg gccgccctgc
    20221 cgcgtccccg gcatcgcgac gccggccccc gcgcctcggc gccggccccc tctcccggcg
    20281 cgtcggcgcc cctccccacg cgcgggcgcg cgccccgcag gacgccgtag actcaccggc
    20341 cggttgaccg gtttccgcac ccccgcccgt ctcttttcag ccaacttccg gttgtggcgc
    20401 acccggtggc atgaccaccc cccaaccccc gttccacctg cacggaaagc acctcgcggg
    20461 ccccgcgcac cctacgcggt ttggccaccg cgacgaggcg cacttccctg cacggcgcgc
    20521 gagtgcaacg cttcgtgatc gaatgcttta cgccaagttg ccaagtcgac aatgcaccgg
    20581 gtgccgaact ggccaccggt gcgcgacggg acacagtaga ttcgatcttg actgtcttac
    20641 ggcgggggac tcgtgcagga ccgaggggaa acgtgcagga gcgacacaac cgaggagccg
    20701 cgaccaccga ggggggctta gcaggatgag ccacgactcc actgccgcgc cggaaaacgc
    20761 ggcccggaaa ctctccgggc gccgccgcaa ggagatcgtc gcggtgctgc tgttcagcgg
    20821 cggccccatt ttcgagagtt ccataccgct gtcggtgttc ggggttgacc gccaggacgc
    20881 cggcgtgccg cgctaccgcc tcttggtgtg cggcggcgaa gaaggcccgc tgcggaccac
    20941 agggggcctg gaactcaccg cgccacacgg cctggaggcg atatcccggg cgggcaccgt
    21001 cgtggtgccg gcctggcgat cgatcacctc cccgccgccg gacgacgccc tggacgcgct
    21061 gcgccgggcc cacgaggagg gcgcccgcat cgtcgggctg tgcaccggcg ccttcgtcct
    21121 cgcggcggcg ggactgctgg acggccgtcc ggcgaccacc cactggatgt acgcgccgac
    21181 gctggccaag cgctatccgt cggtgcacgt cgatccacgc gagctgttcg tggacgacgg
    21241 cgacgtgctg acgtccgcgg gcaccgcggc cggcatcgac ctgtgcctgc acatcgtgcg
    21301 cacggaccac ggcaacgagg cggccggcgc gctcgcccgc cgcctggtgg tcccgccgcg
    21361 ccgcagcggc ggccaggagc gctatctcga ccggtcttta ccggaggaga tcggcgccga
    21421 cccgctcgcc gaggtcgtcg cctgggcact ggagcacctc cacgagcagt tcgacgtgga
    21481 gacgctcgcc gcccgcgcgt acatgagccg ccgtaccttc gaccgccggt tccgctcgct
    21541 gaccggcagc gcgccgctcc agtggctgat cacgcagcgg gtgctccagg cgcagcgcct
    21601 gctggagacg tcggactact cggtcgacga ggtggccgga cgctgcggct tccgctctcc
    21661 cgtggcgctg cgcggtcact tccggcgcca gctcggctcg tccccggccg cctaccgggc
    21721 cgcgtaccgg gcacggcgtc cgcaggccga gcggggccag ggcgacggga ccgcgcaggg
    21781 cgccccgacg ggcggcgtcc cggccggccg gccggagccc gcggggcact cgatgccgca
    21841 gcagctgcac tcggacggag gggtcccgca ccaggcgcgc cggtcggcgg cggccggcgc
    21901 gctggggtcg cccctgaccg cgtcggcgcc gggcgtcccg gggcagcgca gcgcgccctg
    21961 aggtgaccgt cgtgagggcc ggaggccgtg tgcccccggc cctcacccct gcgccgggcg
    22021 acctcaccgc cgtacggaag atcgcgggaa tccccgtttc accacctggt cacgcccggc
    22081 gtcacgcacc gtagggtgag acacatgaac gatcgcatgg tgtggatcga ctgcgagatg
    22141 accggcctct cgctgtcgga cgacgcgctc atcgaggtgg ccgccctcgt caccgactcc
    22201 gagctgaacg tgctcggcga gggtgtcgac atcgtcgtcc gcccgccgga gcgggccctg
    22261 gagacgatgc cggaggtggt gcgcgcgatg cacaccgcgt cggggctgct cgacgagctg
    22321 ccgaacggca cgacgctcga ggacgccgag cagcgggtcc tcgcgtacat caaggagcac
    22381 gtcaaggagc ccgggaaggc gcccctgtgc gggaactccg tcggcaccga ccgcggcttc
    22441 ctgctgcgcg acatgccgac cctggagagc tacctccact accggatcgt cgacgtgtcc
    22501 agcatcaagg agctggcccg ccgctggtac ccgcgggcgt acttcaacag ccccgagaag
    22561 aacggcaacc accgggcgct cgccgacatc cgcgagtcca tcgcggagct gcgctactac
    22621 cgcgaggccg tcttcgtgcc gcagccggga cccgactccg acaccgcgaa gaagatcgcg
    22681 gcgaagcacg tcctgcctgc tcactagggc cgtcgagggg gctcggggga gcggcgcgga
    22741 aaggcgtgcg cgagcacccc ttcggaccct gtacactttt tctcggccgg tcggggaagt
    22801 cactgatctc ccggaaacag gccgtggtgg gtgtagctca gctggtagag cacctggttg
    22861 tggtccagga tgtcgcgggt tcaagtcccg tcactcaccc tgaatgatca agggctgacc
    22921 tgtgcaaacg ggtcagccct tcgtcatgcc cggactttgg gaacttgtgg gaacacggag
    22981 ccctgtcagc cgcccgattc gggccgtatc ttccctccag ggcgagcatc gttccccgcc
    23041 cgaagaagtc gggcgacacc acgtaccagg tgacgtctcg ggaaggacgt cgcccaccac
    23101 gagaccaggc tccgcaccct cgagcgagcc cgctggccgc tccccaccat cggcgtcctc
    23161 gccggtgtgg cgggcgcagg tgcgacagcc ctcttcgcgc ggtgaccacg accccgctct
    23221 cccctgtggg aggggggtcg tttcgtcatg cctggcccaa cctcctggtg gggagctctg
    23281 cccctggtcc tgcggcgtac cgtggcaacg tggcaaacga cgacctcggg cgcaccctcc
    23341 gccgcctacg ccggctggcc tccctcaccc aagaggagct ggcctcccgc tcgggcgtct
    23401 ccgtcgacgt gatccgccaa cttgagcagc gccgcaagca ctccgcgcgg ctaccgacgc
    23461 tgcacgccct ggccaacggg ctgggcgtgg agctgaccac gctgctgggt gatccgcccg
    23521 cagtctcctc gtccggtgag aacgacgggc cgcagttcgt ggctgtgcgc cgggccatca
    23581 tgcctgctct ctggggaccg gaaccgccgc cgccagggcc ggacttcacc ttggatgggc
    23641 tacgcgggca gatcgccgac ggctggacgc agtaccacgc cgctgagttc gacacggtga
    23701 tgaaagccat tcccgacctg atctctgatg cgcgctctgc cgccgcatcg ggtagcgagg
    23761 atgagcgcgg agctggttac gcggccctgg gcaaggtgct tcagttggcc gggcacgtag
    23821 ccgtgcggat gggcaagacg gaccttgctc tgatcagtct tgagcgggcc atagacgctg
    23881 ccgaacagtc gtctgatccg ctgctgctgc cgatgatcgt caactccacg gcgtggacgt
    23941 accagaggca aggccgtctg gcggacgcgc tgggcatcgc gctccgagct gccgacaaca
    24001 tggccgacct tggcctcact ggtacagccg acggcctgaa ggtctggggc gggctgacca
    24061 tgagcgccgc cacgtcagct gcccgtagcg gcgactacga gcgcgcagcc gcgatgatgg
    24121 agacagccga gaaggaagcc gcccgcgtct cgaagatgcc ggacggcggc gacaaacgca
    24181 tggtgagcgt gttcagccct tcgtcggtcc gtgtcgaacg ggtgcggctt gctgtccagt
    24241 acgggcatcc gcgtgacgct ctggcgctcg ccaaggggat gcgactcagc aaggacactc
    24301 ccccgtcgtg gcggacgtgg ctgctgctgg acgtcgcccg tgctcacgct gatatcggag
    24361 atgcggccgg ggcggtgaag accctggaat ccctgcggcg ggtggcgcct gcctggatgc
    24421 agcaccacac gctggccgtg gcgatcgtgc gtgatctgtg ggcgctgccc catcatccgc
    24481 cggggctcgg ggcgctggcg gacttcctgg gggtcagcga atagcgtcgg gaaagtagga
    24541 cgcaccgtcc ctgtcactct gtgtagctcg gcgattccat agtcgggaag cgccccggcg
    24601 accgcgcgaa cggccccggg gccggccgac cgccaaggag tcgacgtgac gcaccgtacc
    24661 gccgcagcgc ccccgccgtc aggatccccc agagccgcct tactcgaagt ggccgccgac
    24721 gtcctggccg tcctgttact gccgtctccc gaggacgcca ccgaggacca gctgcgcggc
    24781 gccggctgca tctggtgcga gaccgggccc ctgaacgctg agacagccat cgacttcggt
    24841 gagcagaaga ccctggcggg agaatcctgg ttcccgcgcg cctgcctgcg ctgcgccgcg
    24901 gcctgggcgc accggggcct gttcgagcac gcaccgctgt gcgagcagtg cacggacgag
    24961 gtgagccgct gcgagatcgg cctggcgttg taccggctga ttcgccaggg acggcgcccg
    25021 tagagactcc ccgcccggcc gctgaatccc gcgaagaaca cccggccggg cggggccatc
    25081 ccatccgcga tcagcgaagg agaacgattg tgaccttacc tccgggcccc atggacccgc
    25141 ccgataaccc cgccctgccc gtcctcgcgc gcatgctcat cgccgacgag cggttcgcgt
    25201 cttgccgtag cacggtgatg gacgccaacc ccggcatgag cgaggagatg gccggccgga
    25261 tcgtcgaaga gggcatcaag ttcgtcgcgg cctgctctcg caatccgggc accgggctgg
    25321 cgccgtcacg gatcgtcgac gagggctggc acgccctgat cctgcacacg gccatgtacg
    25381 ccgagctgtg taccaacctc ggcggcatgt tcgtccacca ctaccccggc tacgacccca
    25441 ccaactacga cccgtccatc ctggaccgga cccgcgaggc catcgccgcg ctgggctggg
    25501 aagcggaccc ggagctgtgg gggccgccgt tcggcgagac gctcgtcccg gtcgcggcga
    25561 agtgccagca cgcaccggac tgcaccgtcc gaccgatgcc gaaaccggaa cccccggtcg
    25621 tgtgagcccg tagcctgagc ggctggaggt ggccatgtcc gagtggatcg acccgcggta
    25681 cgcggagctg gtcgcggtgt ggaagcgcgc gcagcagccg gagtcccgca gcccgcagga
    25741 accgcagcct gtgcgggggt tcgtagtcct gcgcaagccc tgagaccaac cgacccgcca
    25801 gggcgagacc gcggctccca gtgcccgtca ctgggagacg ccatggtgct gcgggtcgct
    25861 cagcgcacga ggtcggcgag tgggacgtcg atggcgtcgg cgatgcggat cagggtgtcg
    25921 agcaggggcg aggagtggcc ctgctcgatg cggctgtagc tgacggcgtc gatgccggac
    25981 cggccgcaca cctcgagctg tgtgaggttg tggtgctcgc gtacgcggct tccggcgttt
    26041 ccggccgggc gcgggcgccc cccccggccg gacaggcgcg ctcaggacga cgcgcgctcc
    26101 accagttccg tcgccagcac catctgacgc cgctccagct cccgcgtcgc ggacgggcgg
    26161 cggtcggcga cctcggccag caggaggtcg gtcatcgccc ggcccatctc ctcgatcggc
    26221 tgacgcacac tggtcagcgg cggctccatg tgccgggcga tcgcggagtc gtcgtacccg
    26281 accagcgcca cgtcgtccgg gatgcggcgg cccgcctcgc gcagcgcctg acgggcgccg
    26341 gccgccgtga cgtcggaggc ggcgaagacc gcgtccaggt cggggcggcg ctccagcagg
    26401 gcctccatgg cgcggcggcc gccgtcctcg gagaagtcgc ccggctcgat cagcagctcg
    26461 tccaccgggt gacccgcctc gcgcagcgcg tcccggtagc cgtcgacgcg gcgctcggcg
    26521 ccgtagacgt ccaggcggcc ggtgatgtgg gcgatggtgc gacggccgcg ggagatgagg
    26581 tgctccaccg cctgccgggc gccgccgtag ttgtcggagt ccaccgaggt gagcgtctcg
    26641 tccgcggagc ggggaccgct gatcacggcg gggatctcca gctgggacag catgtcgggc
    26701 agcgggtcgt cggcgtgcac ggagaccagc agcacgccgt ccacgcggtg cgcggccagg
    26761 tactgggcga gccgctgccg ctcccggtcg ctgcccgcga agatcagcag cagctgcatc
    26821 tcggtgtcgg acagcgcggc gccgacaccg cggagcatgt cggagaagta gggctcggtg
    26881 aagaaccggg tctcgggctc gggcaccacg agcgctatgg cgtcggtgcg gttggccgcc
    26941 agcgcgcggg ccgccgtgtt ggggacgtag cccagttcgg cgacggccgc ctcgacggcg
    27001 gcgcgggtgg cctcgctcac ccggggggag ccgttgatca cgcgcgacac ggtgccgcgg
    27061 cccactccgg cccgcgctgc cacctcttcg agggtggggc ggccaccgct tcggccccgc
    27121 actccgtggc ttgccatccg cccccgcctt ccttctgtgt caccctggcc tggaatgtaa
    27181 cagccccggc agtgacggtg accacccgcg agggcgtccg cgcggacccc ggcgttccga
    27241 gggggcggac ctccgggtca agttaacggg cagataactg aaggcacttt gccgtgtctg
    27301 ttcccttgac acccccgccc ggacccgcga ctcttcaaca catcacttgt gggagcgctc
    27361 ccacagtacc tgacacatac acaacccgca cgttccccgc ccgagccgca acgcgcagaa
    27421 tacgggtcaa caacgccgtt ggccgggggg tcggcacgtc agggcaacag gaggacgcaa
    27481 tgcgagcacg taccctgccc ctcaccaggc agcggtcggg cggggggcag cccttcgccc
    27541 gcaaggcgct ggccgtcgcg gccgtcgtgt cgctgggcac cgggctgctg gccggctgcg
    27601 ccgacgacgg cggcgacgac agctccggtg gttcctcgtc cggcgagggc aagaccacga
    27661 tcaccctggg cctgttcggc accatgggct tcaaggaggc cggcctctac gccgagtacg
    27721 agaagctcaa cccggacatc aagatccagg agaacgtggt cgagcggaac gagaactact
    27781 accccgctct cgtcaaccac ctgaccacca acagcgggct gatggacgtg caggccgtcg
    27841 aggtcgccaa catcgccgag gtcgtgggca cccaggcgga caagttcacg gacatgtcca
    27901 aggtcgaggg tgtgaagaag gaaggctggc tgccctggaa gtgggagcag gcgaccacca
    27961 aggacggcca gaccatcggt ctcggcacgg acgtcggccc gatggccatc tgctaccgca
    28021 aggacctctt cgagaaggcc gggctgccga gcgaccgcgc ggaggtcggc aagctctggg
    28081 cgggcgactg gaacaagttc atcgccaccg gtgagaagta caagaaggcg gccggcaagg
    28141 acaccttctt catggactcc cccggcggcc tgctgaacgc cgtgctcagc agtgagaagg
    28201 agaagttcta cgacgcctcc ggcgaggtca tctacaagac caacccggcc gtcaaggacg
    28261 ccttcgacct gaccgccgag gccgccgaga agggcctggt ccagtcgcag acgcagttcc
    28321 agcccgcctg ggacaccacg atcgccaaca gcaagttcgc caccgtcgcc tgcccgccgt
    28381 ggatgctcgg ctacatcaag ggcaagtcga agcccgacgc ggccggcaag tgggacgtcg
    28441 ccgtggcccc gaagtccgga aactggggcg gctccttcct gggcgtgccg aagagcggca
    28501 agaacgtcga ggaggcgcag aagctggtcg cctggctgac cgcgcccgag cagcaggcca
    28561 agctgttcaa ggtccagggc tccttcccga gcgccccggc cgcgtacgac agcccggagg
    28621 tgaccggcgc caccaacgag atgaccggtg acgcgccgat cggtgagatc ttctccgagg
    28681 ccgccaagca gatcccggtc caggtgatcg gcccgaagga ccagatcatc cagcagggtc
    28741 tgaccgacaa cggcgtcatc ctcgtcacca agggcaagtc ggccgacgag gcgtgggaga
    28801 cggccaccaa gaccatcgac aacaacctgg accagtgacc cgcatggcca cccgctccga
    28861 catcgccgcg tcccccgtca aggggggcgc ggccccgggc cgtacgcccg ggagccactc
    28921 cacggacaag gaaggccggc gcagggccag gctgtcgcgc cgctggcagc gcgacgcccg
    28981 ctggagcccc tacgcgttcg tcgccccgtt cttcctgctg ttcgcggcct tcggcctgtt
    29041 cccgctgatc tacaccggct gggcctcgct gcaccaggtc gagctgaccg cgccgaccga
    29101 catgaactgg gtcggtctga agaactacac acggatcttc gacgacgact tcttctggaa
    29161 cgcggcgcag aacacgctga ccatcggcat catctccacc gtcccgcagc tgatgatcgc
    29221 catgggcatc gcccacatcc tcaactacaa gctgagggcg tccacgttct ggcgggtcgc
    29281 gatgctcgcg ccgtacgcca cctcgatcgc cgccgcgacc ctggtgttcg tgctgctctt
    29341 cggccgtgac tacggcatga tcaactgggc gctcggcgcg gtgggcatcg acccgatcgg
    29401 ctggcaggac gacaagtggc ccggccagat agccgtctcg accatcatca tctggcgctg
    29461 gaccggctac aacgcgctga tctacctggc cgcgatgcag gcgatcccgc aggacctgta
    29521 cgagtcggcg gcgctggacg gcgccagccg ctggcggcag ttcctgcacg tgacgctgcc
    29581 ctcgctgcgt cccacgatcc tgttcaccgt cgtcgtctcg accatcggcg cgagccaggt
    29641 cttcggcgag ccgctgctgt tcgacccgaa caagggcgcc tcgggcggcg ccgagcacca
    29701 gttccagacg ctcggcctgt acctgtacga gcagggctgg atcaaccagc acctgggccg
    29761 tgcctcggcg atc
//
