LOCUS       NZ_BMTZ01000015        24133 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces variabilis strain JCM 4422 sequence15, whole genome
            shotgun sequence.
ACCESSION   NZ_BMTZ01000015
VERSION     NZ_BMTZ01000015.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces variabilis
  ORGANISM  Streptomyces variabilis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces griseoincarnatus
            group.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 172639)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: BGI assembly pipeline
            Genome Coverage                   :: 156X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014649935.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:37:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,743
            CDSs (total)                      :: 6,668
            Genes (coding)                    :: 6,496
            CDSs (with protein)               :: 6,496
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 172
            CDSs (without protein)            :: 172
            Pseudo Genes (ambiguous residues) :: 0 of 172
            Pseudo Genes (frameshifted)       :: 61 of 172
            Pseudo Genes (incomplete)         :: 147 of 172
            Pseudo Genes (internal stop)      :: 11 of 172
            Pseudo Genes (multiple problems)  :: 42 of 172
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:23:51
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 86174
            Orig. end                         :: 110307
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMTZ01000015.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24133
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24133
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24133
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14133]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14133
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            415..927
                     /locus_tag="IE148_RS22335"
                     /old_locus_tag="GCM10010287_45160"
     CDS             415..927
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004992126.1"
                     /locus_tag="IE148_RS22335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_45160"
                     /product="hypothetical protein"
                     /protein_id="WP_189365770.1"
                     /transl_table=11
                     /translation="MTAQGPDDGGTPQDREDGVPSVPDDVWQRFLMDSEQAIRTSAPRE
                     PSAVQRAAGRSPQLPPPAPTKPPRRDTPEAVGDLWQPDDPWEGPAWRDLDGRARLRRVG
                     RVVGTAAAIALALGAWSQLSTGAGTPAEGPGDTVLQQSEEAPVTLPPGTSVPAGLTTPS
                     ATEIQAG"
     gene            complement(962..2602)
                     /gene="pgm"
                     /locus_tag="IE148_RS22340"
                     /old_locus_tag="GCM10010287_45170"
     CDS             complement(962..2602)
                     /EC_number="5.4.2.2"
                     /GO_function="GO:0004614 - phosphoglucomutase activity
                     [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pgm"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019525645.1"
                     /locus_tag="IE148_RS22340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_45170"
                     /product="phosphoglucomutase
                     (alpha-D-glucose-1,6-bisphosphate-dependent)"
                     /protein_id="WP_189365771.1"
                     /transl_table=11
                     /translation="MQHERAGGPAGPEDLVDVARLVTAYYALHPDLDDPGQRVAFGTSG
                     HRGSSLAAAFNEDHIAATSQAICEYRAAQGTDGPLFLGADTHALSEPARVTALEVFAAN
                     GVTVLIDSADGYTPTPAVSHAVLTHNRGRGTGLADGVVVTPSHNPPADGGFKYNPPSGG
                     PAGSDATGWIQERANEIIRGGLKDVRRIPYTRALAAPDTGRYDFLGTYVADLPSVLDLD
                     AVRAAGVRIGADPLGGASVAYWGRIAEEHRLDLTVVNPLTDPTWRFMTLDWDGKIRMDC
                     SSPHAMASLIGQRDRFDIATGNDADADRHGIVTPDAGLMNPNHYLAVAIGYLYAHRAQW
                     PSAAGVGKTLVSSAMIDRVAADLKRDLVEVPVGFKWFVDGLVDGSLGFGGEESAGASFL
                     RRDGSVWTTDKDGIILALLASEITAVTGKTPSQHYAGLTARFGEPAYERIDAPATREEK
                     ARLAKLSPAQVTADTLAGEPVTAVLTEAPGNGASVGGIKVTTESAWFAARPSGTEDVYK
                     IYAESFQGPEHLRRVQEEAKGVVLAALGG"
     gene            complement(2711..3139)
                     /locus_tag="IE148_RS22345"
                     /old_locus_tag="GCM10010287_45180"
     CDS             complement(2711..3139)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006136700.1"
                     /locus_tag="IE148_RS22345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_45180"
                     /product="hypothetical protein"
                     /protein_id="WP_189365772.1"
                     /transl_table=11
                     /translation="MTEQNKNANRKTSTAGSTASKAASTADKATASAKSAADGAAAKAS
                     DAASAAASGTERAARAANGAAQSAVKGVEAGRRAVVTASGQVASGAKTAWTVIANRRLV
                     AAGAAAGLTALTAASYAVGRRAERHTHGPLTRMTGGRI"
     gene            3329..3478
                     /locus_tag="IE148_RS22350"
                     /old_locus_tag="GCM10010287_45190"
     CDS             3329..3478
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007389477.1"
                     /locus_tag="IE148_RS22350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_45190"
                     /product="hypothetical protein"
                     /protein_id="WP_122213162.1"
                     /transl_table=11
                     /translation="MPGMVERIKQFARSPQGRRAAEQVRRAAADPRKRAQAQRLLGRLR
                     GGRR"
     gene            3548..3967
                     /locus_tag="IE148_RS22355"
                     /old_locus_tag="GCM10010287_45200"
     CDS             3548..3967
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019525642.1"
                     /locus_tag="IE148_RS22355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_45200"
                     /product="ATP-binding protein"
                     /protein_id="WP_048458314.1"
                     /transl_table=11
                     /translation="MNESSVRTVGWARSLPMGQGVKAARDWAQEHLASLGWDETAPDTV
                     HSVLLTVSELVTNAHVHAGTDAQLVMAWDTRCLHISVHDGSASLPTPREPSEERVGGRG
                     MLLVDVLADTWEARPCPHGKTVTACFRAPEAAAAV"
     gene            4070..4807
                     /locus_tag="IE148_RS22360"
                     /old_locus_tag="GCM10010287_45210"
     CDS             4070..4807
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019525641.1"
                     /locus_tag="IE148_RS22360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_45210"
                     /product="adenosylcobinamide amidohydrolase"
                     /protein_id="WP_189365773.1"
                     /transl_table=11
                     /translation="MTAALPPYPVTPALPAPHRLTRTEDGARLHALLWTAGPGRRAISS
                     AVLGGGIGRRAWILNAQVSHGYRRTDPERHLACLAADAGLSGPGVGLMTAADVSAYAHA
                     RDGGVEAFVTAGVDVRDWAARPGEGAEGAPEPGTINVVVAVPAALTDAALVNAVATATE
                     AKVQALVESGHDCSGTPTDAVCVVADAPAPDREAYAFAGPRSLWGARLARAVHRAVRDA
                     VAEGVPGGPGTSGVTHGTPVPGY"
     gene            4931..6580
                     /locus_tag="IE148_RS22365"
                     /old_locus_tag="GCM10010287_45220"
     CDS             4931..6580
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004921668.1"
                     /locus_tag="IE148_RS22365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_45220"
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /protein_id="WP_189365774.1"
                     /transl_table=11
                     /translation="MISSPGSSADPCHARDQSVPTWDDAPCPVLVLDSRGRIAGRNRAA
                     RRLTASSRDSDVPPSWLGEAHRSHVAGALDPTAATPAGLLGDRSFEARPSPTGDGHVAW
                     WLFDRTDLVRAQETVRETRERADVTSGLFSTLLSSLNVPRCAEVAALMAADHLAEAAVL
                     ITPPAGHRYAVTHALRGRRVVQETRQIDPLTVPGLDEALRGFPPVPARWINPDAIPAWA
                     IPDGFSGPVGSVLVTPLPGHGVPAGALILLRSDTEKGFTPEEEEFARLFASRAGTALSA
                     ARLYGEQTAITGTLMRELLPPPLSRVHGVDYAGRYRTAMDHERVGGDFYDVHPGPDGSA
                     ETFVALGDVAGKGLDAAVLTGKIRNTLHALLPLASDHLRVLRMLNGALLTSHHARFATL
                     VLASVKRQDDGPVRLRLTGAGHLPPLVVRADGRVEEMPTQGTLVGALPEVTARTVETVL
                     GPGDTCLLYTDGITEARGGPLGDELFGEERLRQALEGCGGMPGEAMVEHVQMLAAQWLE
                     PGSRHDDMAVVAITAPRNGGPAGDRAPAGADG"
     gene            6598..7677
                     /locus_tag="IE148_RS22370"
                     /old_locus_tag="GCM10010287_45230"
     CDS             6598..7677
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019525639.1"
                     /locus_tag="IE148_RS22370"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on a
                     cobalamin-like analog.; Presence of a B(12)
                     (cobalamin)-binding domain implies dependence on cobalamin
                     itself, in one of its several forms, or in some unusual
                     lineages, dependence on a cobalamin-like analog.; Presence
                     of a B(12) (cobalamin)-binding domain implies dependence on
                     cobalamin itself, in one of its several forms, or in some
                     unusual lineages, dependence on a cobalamin-like analog.;
                     Presence of a B(12) (cobalamin)-binding domain implies
                     dependence on cobalamin itself, in one of its several
                     forms, or in some unusual lineages, dependence on a
                     cobalamin-like analog; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_45230"
                     /product="B12-binding domain-containing protein"
                     /protein_id="WP_189365775.1"
                     /transl_table=11
                     /translation="MSGGPRASAGELGEALWKAVIDGDEYDAVDVVRGALAGGWQEEDL
                     LLDVVAAVQARIGLEWAADRITVAQEHAATAINERVITALVHNGSGRRPEAVRGRVTVS
                     CVDGEWHAFPARLVAETLRLRGWQVDYLGAQTPTPHLVAHQHHTNSDAVLLSGSIPTHL
                     PRAHTAINACRSVGVPVVAGGRAFGVDGRYARALGADAWAPDARGAAAVLEAGLARPTN
                     VRQAVDDLPHLADQEYSMVVRSRGRLVKETLAELERRFPPMREYSDAQRERTAEDLAHV
                     VDFLATALYVDAVEVFTEFLGWTADVLSARNVPPHSLVTGLDILTDRLHDFPRVLAVIR
                     AGAARLTDRTDPAVTDTVV"
     gene            complement(7714..9279)
                     /locus_tag="IE148_RS22375"
                     /old_locus_tag="GCM10010287_45240"
     CDS             complement(7714..9279)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019525638.1"
                     /locus_tag="IE148_RS22375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_45240"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_189365776.1"
                     /sec_met_domain="DAO (E-value: 2.5e-13, bitscore: 43.6,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRPPRPAAARRGRDRRARVIMPAPGAPRADGDRRPSTAVVGGGI
                     AGLAAATALAERGVDVTLYEARPYLGGRVGGWPVDLGDGTPATMSRGFHAFFRQYYNLR
                     GLLRRTDPALERLTPLPDYPLRHSDGMHDSFRHVPRTPPWSAIGFAALSPSFPLRDLPR
                     MNAAAALPLLDVRVPDIYARLDAVSAHDFLDAVRFPESARHLAFEVFSRSFFADPRLLS
                     AAEMALMFHIYFLGSSEGLLFDVPTAPFPTALWEPLAALLERHGADLRTSTPVEHVEPL
                     DDGGYEVATDREARRHDTVVLALDAVGLRALVDRSPLLGDTPWRERTARLRNAPPFLVS
                     RLWLDRPVAPDRPGFLGTGGYGTLDNVSVLERYEDEAARWAARTGGSVVELHAYALPPE
                     AAPEVEQKRLLDQLHRIYPETRGAGIVDARHEWGTDCPLFPVGGYEDRPTVRTPDPGLM
                     VAGDLVRTSLPVALMERAATTGFLAANALLERWGVRGQPLWTVPDRGRSAVLRGLAGAL
                     GRRG"
     gene            complement(9276..10004)
                     /locus_tag="IE148_RS22380"
                     /old_locus_tag="GCM10010287_45250"
     CDS             complement(9276..10004)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019525637.1"
                     /locus_tag="IE148_RS22380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_45250"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_189365777.1"
                     /transl_table=11
                     /translation="MTLLRDEHLAAAFDHAARSYDTLVAANPGYHAHLRRSARRLGLPR
                     GGEGLRVLDLGCGTGASTGALAEVLPSADITAVDASAGMLERAAAKTWPPNVTFTHAPA
                     ERLAEAGVTGPFDAVFAAYLFRNVTDPDAVLRTVHGLLAPGGRLAVHEYTLGGRRTDRA
                     VWTLVCRGVVQPVATLLGDGDLYRHLWRSVVGFDTADRFADRLRANGFTSVRRLPLPGW
                     QTGITHTFTGRRPTRTETAR"
     gene            complement(10001..11239)
                     /locus_tag="IE148_RS22385"
                     /old_locus_tag="GCM10010287_45260"
     CDS             complement(10001..11239)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144563.1"
                     /locus_tag="IE148_RS22385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_45260"
                     /product="lycopene cyclase family protein"
                     /protein_id="WP_189365778.1"
                     /sec_met_domain="Lycopene_cycl (E-value: 2.7e-102,
                     bitscore: 335.9, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEADVAIVGAGAAGLSLAHRLAGPGSGRRAPSVVLLDAPPGPLR
                     PPRRTWCFWEAGPGRFDAAVTASWRSLRVRDRGGRPIDGDIAPLRYKMIRSDDFEHLVA
                     RDLAGHDGVRRVEGTVDTVEDVPGGALVRLRDRDGDPRVVGARWVFDSRPPGSLPAART
                     TLLQHFHGWFVRTARPAFAPGTAELMDFRTPQPADGLSFGYVLPLGRHDALVEYTEFSP
                     RPLTRDAYEAAVRHYTDDVLRLGDLEVLSTETGVIPMTDAVMPRRTGQSVFRIGAAGGA
                     TRPSTGYTFAGLQRQTRAVAAAIREGRRPVPPPAHSARSRAMDAVLLRALAGGRADGPA
                     LFCRLFDRVPMRRLLRFLDGDTRLHEDLAVGLHAPVGPMLRSALELPGLPRRPYERPLN
                     PPTCPAPATPETP"
     gene            11586..13130
                     /locus_tag="IE148_RS22390"
                     /old_locus_tag="GCM10010287_45280"
     CDS             11586..13130
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019525635.1"
                     /locus_tag="IE148_RS22390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_45280"
                     /product="phytoene desaturase"
                     /protein_id="WP_189365779.1"
                     /sec_met_domain="DAO (E-value: 2.9e-18, bitscore: 59.8,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTVPGRTDHVVVVGAGLAGLSAALHLLGAGRRVTVVERDGLPG
                     GRAGRLELDGYRIDTGPTVLTMPDLADEPFAAVGDSLRKRVELVPLHPAYRARFADGSS
                     LDVHTRAEPMAAEVERFAGAREAAGYLRMREWLERLYRAQMRRFIDANFDSPLGLLHPD
                     LARLAALGGFGRLDARIGSFLKDERLRRVFSFQALYAGVPPARALAAYAVIAYMDTVAG
                     VYFPRGGMHALPQAMADAAADAGADLRFGREVTRLERSGGRVTAVVAGEERIPCDAVVL
                     TPDLPVTYRLLGGAPRRPVRLRHSPSAVVLHLGTDRTWPELAHHTISFGEAWRGTFDEL
                     TRAGRLMSDPSLLITRPTATDPSLAPPGRHLHYVLAPCPNTDIGPGAAEWTDLAPRYRD
                     TVLRTLEGRGLTGLASAIETECVVTPADWTAQGHAAGTPFATAHTFAQTGPFRPRNLVR
                     SAGNAVLAGCGTTPGVGVPTVLLSGKLAAARITGAGGPVGRASTSSSAQEALHDRA"
     gene            13117..14133
                     /locus_tag="IE148_RS22395"
                     /old_locus_tag="GCM10010287_45290"
     CDS             13117..14133
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670294.1"
                     /locus_tag="IE148_RS22395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_45290"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_189365780.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.3e-120,
                     bitscore: 394.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.7e-63,
                     bitscore: 207.2, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTERELDAAGITDPVLREAYDHCRRLNARHGRTYFLATRLLPVER
                     RPAVHALYGFARWADDIVDALGTGADTARRDAELAALERELAKGLRDGESAEPVVRALA
                     DTARRYGIDHAHFADFMTAMRSDLVVTDYADYAALRRYMHGSAAVIGLQMLPVLGTVTD
                     RGTAAPHAAALGVAFQLTNFLRDVGEDLDRGRVYLPADLLAAHGVDRERLRWSRDTGRR
                     DPRITSALRAFERLTRGVYRQAAPGLAMLEPVSRPCIRTAFVLYGGILDAVAEDGYAVL
                     HRRSVVPRRRRAVVAADGLARVAAARLRARSAAARGTERAPLTAPEPVEPRMVEEVA"
     gene            14133..15137
                     /locus_tag="IE148_RS22400"
                     /old_locus_tag="GCM10010287_45300"
     CDS             14133..15137
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019525633.1"
                     /locus_tag="IE148_RS22400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_45300"
                     /product="DUF5914 domain-containing protein"
                     /protein_id="WP_189365781.1"
                     /transl_table=11
                     /translation="MAGDGRRRRLPLSLRRNAVAWERQRPTWRDAKPALIAGALKRAQA
                     RPSGNWYVVGSSRDVGGDRPLGRTVAGQEVVVWRDTGGRVVAGPGVCPHLGAPLRDSPV
                     RCGTLVCHWHGLSLDGGPFAGWEPFPAYDDGVLVWVRLDAVGGEEPLDAPVVPSRPVPA
                     RALTAVYAGVGVCEPEDVMANRLDPWHGAWFHPYSFVDLTVADTPESAGEDAFAVDVSF
                     KVAGRLVVPVRAVFTAPEPRTVVMHITEGEGVGSVVETHATPLGPDASGRPRTAVVEAV
                     VAASDRRGFALARAAAPVLRPLVRAASGRLWRDDLAYAERRWALRSTGRFPGA"
     gene            complement(15638..16516)
                     /locus_tag="IE148_RS22405"
                     /old_locus_tag="GCM10010287_45310"
     CDS             complement(15638..16516)
                     /NRPS_PKS="Domain: PKS_KR (9-172). E-value: 6.7e-16. Score:
                     50.7. Matches aSDomain:
                     nrpspksdomains_IE148_RS22405_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677153.1"
                     /locus_tag="IE148_RS22405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_45310"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_189365782.1"
                     /sec_met_domain="adh_short (E-value: 6.8e-32, bitscore:
                     104.2, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDGPLGGRTAVVTGAARGIGAGLARELAARGMRVALLGHEGDRL
                     RQLADDLPAPALAYEVDVTDDVALEQAADAVRTGLGTPSVVVANAAVADAGPFADSDPA
                     RWGRIVDVNLTGSANTARTFLPDLTAAKGHYLQVASLAAIGAAPMMSAYCASKAGAEAF
                     AHSLRAEVAHLGVTVGLGYLTWIRTDLIEDADRHGVMQELRGHMPWPVRDVYPPDRAAA
                     RLAQAVERRSTAVYYPRWLRLAQPVRAAMPAVVTRATRHYLPRIEARSSLTHTDLLGGG
                     GRADSEAARPS"
     aSDomain        complement(16001..16489)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE148_RS22405_PKS_KR.1"
                     /evalue="6.70E-16"
                     /label="IE148_RS22405_PKS_KR.1"
                     /locus_tag="IE148_RS22405"
                     /protein_end="172"
                     /protein_start="9"
                     /score="50.7"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TAVVTGAARGIGAGLARELAARGMRVALLGHEGDRLRQLADDLPA
                     PALAYEVDVTDDVALEQAADAVRTGLGTPSVVVANAAVADAGPFADSDPARWGRIVDVN
                     LTGSANTARTFLPDLTAAKGHYLQVASLAAIGAAPMMSAYCASKAGAEAFAHSLRAEVA
                     "
     CDS_motif       complement(16400..16483)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE148_RS22405_0001"
                     /evalue="1.90E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE148_RS22405"
                     /protein_end="39"
                     /protein_start="11"
                     /score="14.1"
                     /tool="antismash"
                     /translation="VVTGAARGIGAGLARELAARGMRVALLG"
     gene            complement(16513..16998)
                     /locus_tag="IE148_RS22410"
                     /old_locus_tag="GCM10010287_45320"
     CDS             complement(16513..16998)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019525631.1"
                     /locus_tag="IE148_RS22410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_45320"
                     /product="hypothetical protein"
                     /protein_id="WP_048458305.1"
                     /transl_table=11
                     /translation="MSGRNGRPDDGPDRRHQRPEGLSDETVEALGSLSKALETTERARG
                     HLYSFHQLTGTADLELDRAVELLHKAGHPDWAEAVRTQVLGRNVIPGHWTFQIVEAYDH
                     TYYRPFRELEQAAVEELADGRDHLFEAEMKEARRTAGHPHHTARPDVDPQITGGDGG"
     gene            complement(17057..18700)
                     /locus_tag="IE148_RS22415"
                     /old_locus_tag="GCM10010287_45330"
     CDS             complement(17057..18700)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019525630.1"
                     /locus_tag="IE148_RS22415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_45330"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_189365783.1"
                     /sec_met_domain="DAO (E-value: 5.4e-09, bitscore: 29.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADAVVIGAGPNGLVAANLLADAGWSVTVLEEQPEPGGAVRHDHG
                     VHPDFANDLFSSFYPLAAASPVVSGLGLEEHGLRWSHAPHVVAHPLSDGRCAILDRDVD
                     VTADSLDTFAPGDGDAWRRLYSMWDTLRPDLLDALFTPFPPVRSGLRLAVRLRGTGGLR
                     MARTLVLPVRRMAEEEFRGEGGGLLLAGNALHADLAPEAAGSGGFGWLMSMLGQTYGFP
                     VPVGGAGALTDALVRRLESRGGALRCGRHVERVVVRDGRAVAVRLADGETVPARRAVLA
                     DVSVPALYGELVAPEDLPRQLLSDLERFQWDFATFKVDWALDGPVPWQCEQAAGAGTVH
                     LADGLDELTRFAAQLAMGRVPDRPFSLFGQMTTSDPTRSPAGTESAWAYTHVPHRVVGD
                     AGDDGITGSWDKDEQERMADRVEAHVERFAPGFRDRVRARRILAPPTLQNLDRNLHGGA
                     INGGTAAMHQQLFFRPAPGTGRPEAPVKGLYLASAGAHPGGGVHGAPGANAARAALRPS
                     FAPGLAAAQRLLAHRDRTGHRQPDRGGRPA"
     gene            complement(18693..19199)
                     /locus_tag="IE148_RS22420"
                     /old_locus_tag="GCM10010287_45340"
     CDS             complement(18693..19199)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (3-141). E-value:
                     3.9e-09. Score: 29.0. Matches aSDomain:
                     nrpspksdomains_IE148_RS22420_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446460.1"
                     /locus_tag="IE148_RS22420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_45340"
                     /product="SRPBCC family protein"
                     /protein_id="WP_189365784.1"
                     /transl_table=11
                     /translation="MAVRHRLIRTDPRTVWSVLEDGTRYADWVVGTSESKPAHGHWPQL
                     GSAIRYEVPVGPLKLHNETVVRRCVPGEVLELEANAGPLGTARIAIEVQPWGDWCLVKV
                     DEHPLRGAGGFLHNVGVEALIQIRHRAMLARLAHLVETEAAETEERRPLGQIVPPEPDA
                     GGARG"
     aSDomain        complement(18777..19190)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE148_RS22420_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="3.90E-09"
                     /label="IE148_RS22420_Polyketide_cyc2.1"
                     /locus_tag="IE148_RS22420"
                     /protein_end="141"
                     /protein_start="3"
                     /score="29.0"
                     /tool="antismash"
                     /translation="RHRLIRTDPRTVWSVLEDGTRYADWVVGTSESKPAHGHWPQLGSA
                     IRYEVPVGPLKLHNETVVRRCVPGEVLELEANAGPLGTARIAIEVQPWGDWCLVKVDEH
                     PLRGAGGFLHNVGVEALIQIRHRAMLARLAHLVE"
     misc_feature    19168..19181
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.86"
                     /tool="antismash"
     gene            complement(19287..20156)
                     /locus_tag="IE148_RS22425"
                     /old_locus_tag="GCM10010287_45350"
     CDS             complement(19287..20156)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006135553.1"
                     /locus_tag="IE148_RS22425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_45350"
                     /product="oxygenase MpaB family protein"
                     /protein_id="WP_189365785.1"
                     /transl_table=11
                     /translation="MKRIAEPASALRGRIGHAIFSRVAGPEGPDNRARIHGTPGPRWFA
                     PESPVRRVHGDASMFIGGLSALLLQSLHPLAMAAVAAHSGFRGDPWGRLQRTSTFLAVT
                     TYGTADSAQRAVDRVRAVHDTVRGTAPDGREYRASDPHLLCWVHVAEVDMFLRAHQRYG
                     ARPLDDAGCDGYVAGMARIATALGVPDPPVNRAQLAERLAAYRDELHATPDALATARFL
                     LLDPPVPLLARLPYGVLAANAVSLLPPWASRELRVPRMPAEALCVRPLGTAVTAGIRWA
                     LAPTRPAA"
     gene            complement(20241..20507)
                     /locus_tag="IE148_RS22430"
                     /old_locus_tag="GCM10010287_45360"
     CDS             complement(20241..20507)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006135555.1"
                     /locus_tag="IE148_RS22430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_45360"
                     /product="hypothetical protein"
                     /protein_id="WP_048458301.1"
                     /transl_table=11
                     /translation="MDETEFMRGRVYGADHDDPGPREGRTYAELSGGPLDGLLLDVTDH
                     GPAERRHGVGLPTEIGRYGPGGRAVYAPRAAGARVYEWRGDVP"
     gene            complement(20620..21405)
                     /locus_tag="IE148_RS22435"
                     /old_locus_tag="GCM10010287_45370"
     CDS             complement(20620..21405)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019983602.1"
                     /locus_tag="IE148_RS22435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_45370"
                     /product="restriction endonuclease"
                     /protein_id="WP_244791475.1"
                     /transl_table=11
                     /translation="MTMPERRTRALRPGRRFDLRSTAMFFGLLAAALVIGGLAVRALAG
                     VVQRRPVWAVVLLCLVLAVAVARGRRRRRLSAAGMARQAGRAFARGTSTALDALDAPAP
                     APLVIPAQAGPVDEVTSPLPVAQGIDHDALTPDEFEAATAELCARDGCTEVQVVGGAGD
                     LGADVTALMPDGRRLVVQCKRYGEDNKVGSQDLQRFGGTCFTVHEADVAVVVTTGEFTV
                     PALEYAEQCGIVCVDGDGLLAWSQGRALAPWAGVREETA"
     gene            21610..22302
                     /locus_tag="IE148_RS22440"
                     /old_locus_tag="GCM10010287_45380"
     CDS             21610..22302
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006132177.1"
                     /locus_tag="IE148_RS22440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_45380"
                     /product="GAF and ANTAR domain-containing protein"
                     /protein_id="WP_189365786.1"
                     /transl_table=11
                     /translation="MDWRLFAQRMASMARDLLAEHTLDATLEQISRSAVELVDGCDAAG
                     ILVLSQGRVRSLAPTDPFVTKSDMLQGELREGPCFDAARPDRPERLFRIPDLTAPPERW
                     PRFVPRARDLGVGSMMGFLLYTREEELGALNMYSRKPGIFTEDSETAGWLLASHAAVAF
                     ATARTDEQMQEAITTRHLIGEAMGILMGRHDVTEDQAFELLRTRSQRTNTKLRDVAREI
                     CEPGGAER"
     gene            complement(22330..22920)
                     /locus_tag="IE148_RS22445"
                     /old_locus_tag="GCM10010287_45390"
     CDS             complement(22330..22920)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003995906.1"
                     /locus_tag="IE148_RS22445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_45390"
                     /product="hypothetical protein"
                     /protein_id="WP_189365787.1"
                     /transl_table=11
                     /translation="MLQPRTICATVVLLGASLVTAAVPAVAAPEAAPAAATACPTGWGS
                     TDKAAAAATSESVRNVRTGRHDCYDRMVVDVPGAARGDLGYSVRYVDRLLQDGSGRHIP
                     VSGGAILEVRVTAPAYDPETGAATYPARAGGVLPGVDLTGYRTFRDARFAGSFEGDTQL
                     GLGVRGRLPFRVQQLDGRLVIDVAHTWTGTAGR"
     misc_feature    complement(23667..23682)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.71"
                     /tool="antismash"
ORIGIN
        1 caccaggtgc acgcggcccg cgggggcggg gacgagacgg tggacgagcg gtgatgtcgg
       61 taccggcacg gctgctccag agtcgctcgg gggcccgcgg acgccggtgc ggctccggaa
      121 ggccctggtc gtaggccgag catgcgccgt cgcgcaacgg agggcgagcg atgttgccgg
      181 ttccgcaaac gcctgccgtg atgacgtcca cggacgccct cgtcgtgcgg ccggcagtcg
      241 gaagcgaaag cacacggtac gcggacggca cccccggtgc cgggcctccg taccgcgttg
      301 ccggtccccc gtttcggcgt tccggcgctg tgcgatgatc ctggcgggcc cgggggcgca
      361 cgtgcgccga ggtgtcgccg gcggggctcc gggacgcgag aggaatggac ggacgtgacc
      421 gcgcagggac cggacgacgg cggaacgccg caggatcggg aggacggcgt gccgtccgtg
      481 cccgacgacg tctggcagcg gttcctcatg gacagcgagc aggccatccg tacgtccgcc
      541 cccagggagc cctcggcggt gcagcgggcc gccgggcggt ccccccagct cccgccgccc
      601 gcaccgacga agccgccccg ccgcgacacc ccggaggccg tcggcgacct gtggcagccg
      661 gacgacccgt gggaggggcc tgcctggcgg gacctcgacg ggcgggcgcg gctgcgccgg
      721 gtcgggcgtg tcgtggggac tgccgccgcg atcgccctgg ccctgggcgc gtggtcccag
      781 ctgtccacgg gcgccggcac cccggccgag gggcccggcg acaccgtgct ccagcagtcc
      841 gaggaggccc cggtgacgct gcccccgggg acctccgtgc cggccgggct caccacgccg
      901 tccgccacgg agatccaggc cggctgacaa ggcgttcaac ggcccgggcg gaggcgcccg
      961 gtcagccgcc cagcgccgcc agcacgaccc ccttcgcctc ctcctgcacc cggcgcaggt
     1021 gctccgggcc ctggaacgac tcggcgtaga tcttgtacac gtcctccgtg cccgaggggc
     1081 gggccgcgaa ccaggcgctc tccgtggtca ccttgatgcc gccgacggac gcgccgttgc
     1141 cgggcgcctc ggtgagcacg gcggtgaccg gctcccccgc cagggtgtcg gcggtgacct
     1201 gggccgggga gagcttcgcc aggcgcgcct tctcctcgcg ggtcgcgggg gcgtcgatgc
     1261 gctcgtaggc gggttcgccg aagcgggcgg tcagtccggc gtagtgctgc gacggcgtct
     1321 tcccggtgac cgcggtgatc tcggaggcga gcagcgccag gatgatgccg tccttgtcgg
     1381 tggtccacac cgagccgtcg cggcgcagga aggaggcccc ggccgactcc tctccgccga
     1441 agccgaggct gccgtcgacc agtccgtcca cgaaccactt gaaaccgacc ggtacttcga
     1501 ccaggtcacg cttcaggtcg gccgcgaccc ggtcgatcat ggccgaggag acgagggtct
     1561 tgccgacgcc cgccgccgac ggccactgcg cgcggtgcgc gtacaggtag ccgatcgcga
     1621 cggcgaggta gtggttgggg ttcatcaggc ccgcgtcggg ggtgacgatg ccgtgccggt
     1681 cggcgtcggc gtcgttgccg gtcgcgatgt cgaagcggtc gcgctgcccg atgagggacg
     1741 ccatggcgtg cggcgacgag cagtccatgc ggatcttgcc gtcccagtcg agcgtcatga
     1801 accgccaggt ggggtcggtg agcgggttga ccaccgtgag gtccaggcgg tgctcctcgg
     1861 cgatgcggcc ccagtaggcg accgacgccc cgcccagcgg gtcggcgccg atgcggacgc
     1921 cggccgcgcg gaccgcgtcc aggtccagca cgctcggcag gtccgcgacg tacgtgccga
     1981 ggaagtcgta gcggccggtg tccggcgcgg cgagggcgcg cgtgtaaggg atgcggcgga
     2041 cgtccttgag gccgccgcgg atgatctcgt tggcgcgctc ctggatccag ccggtggcgt
     2101 ccgatcctgc ggggccgccg ctgggcgggt tgtacttgaa cccgccgtcg gcgggcgggt
     2161 tgtgggacgg ggtgacgacg acgccgtcgg cgagtcccgt gccgcggccc cggttgtggg
     2221 tgagcacggc gtgcgagacg gccggggtgg gcgtgtaccc gtcggcgctg tcgatgagca
     2281 ccgtcacgcc gttggcggcg aacacctcca gggcggtgac ccgcgccggc tcggagaggg
     2341 cgtgggtgtc cgcgccgagg aagagcggtc cgtcggtgcc ctgcgcggcg cggtactcgc
     2401 agatggcctg gctggtcgcg gcgatgtggt cctcgttgaa cgcggccgcc agtgacgagc
     2461 cgcggtgccc cgaggtgccg aacgcgacgc gctgccccgg gtcgtccagg tcggggtgga
     2521 gcgcgtagta cgccgtgacc agccgagcga cgtcgacgag atcctcggga ccggccggac
     2581 cgcccgctcg ctcgtgctgc atgtgcccac tcctccgcaa aaggtcggtt gtcacgcttg
     2641 cggagccatc tttccccgcc ggggcgtcgc cgcgcgagtg ggctcggtcc gctccggccc
     2701 ccgacggacg tcagatacgt ccgccggtca tccgggtcag agggccgtgg gtgtgccgtt
     2761 cggcgcggcg gcccaccgcg taggaggcgg cggtcagcgc ggtcagtccg gcggccgcgc
     2821 ccgcggcgac cagcctgcgg ttggcgatga ccgtccaggc ggtcttggcg cccgaggcga
     2881 cctgcccgga tgcggtgacg acggcgcggc ggcccgcctc cacgcccttc accgcggact
     2941 gggcggcgcc gttcgccgcg cgggcggcgc gctcggtgcc ggacgcggcg gccgacgcgg
     3001 cgtcagacgc cttggccgcc gcgccgtcgg cggcgctctt cgccgacgcg gtcgccttgt
     3061 cggcggtcga ggcggccttg gacgccgtgg acccggcggt cgaggtcttc cggttcgcgt
     3121 tcttgttctg ttcggtcatg gacaccggtt tgccgcaagg ccggtcggca aacacatcgg
     3181 tgacgaggcg ctgctcacgg tcgcgcactg ccaacagggc gggcacggcg cgggcttgag
     3241 attcccggcc gggagcgggc tgtgccgggg ttccgggggt agaagaagga cggcacgcac
     3301 acgccgacgc ctaccgagag gagtcgccat gcccggcatg gtggagcgca tcaagcagtt
     3361 cgcccggagc ccgcaggggc gccgcgcggc cgagcaggtc cgacgggccg cggccgaccc
     3421 tcggaagcgg gcgcaggccc agcggctgct gggacggctg cgcggcggac ggcgctgagc
     3481 cgaccccggg cctgacggtt cctcgcgcgt ccgcgcggac cgcaggccga cgaccggaaa
     3541 ggactccatg aacgaatcgt cggtccgcac cgtgggctgg gcacgctccc tgccgatggg
     3601 gcagggggtg aaggcggccc gtgactgggc gcaggagcac ctcgcctccc tggggtggga
     3661 cgagaccgcg cccgataccg tccactccgt gctgctcacg gtgtcggagc tggtcaccaa
     3721 cgcgcatgtg cacgccggaa ccgacgcgca gctggtgatg gcgtgggaca cccgctgcct
     3781 gcacatctcc gtgcacgacg ggtccgcctc cctgcccacg ccgcgcgagc cgagcgagga
     3841 gcgggtcggc gggcgcggca tgctgctggt cgacgtcctg gccgacacct gggaggcgcg
     3901 gccctgcccg cacggcaaga cggtcaccgc ctgcttccgc gctccggagg ccgccgccgc
     3961 ggtgtgatca ccccggcgcg gggcgcggac ccggcccggc ctacgatcgg tcgggccgac
     4021 ccccgcaagg ccgcccgcga aggccgcccg ccgcaaggag ccccgcacgg tgaccgccgc
     4081 cctgcccccg taccccgtca cgcccgccct gccggccccg caccggctga cccgcaccga
     4141 ggacggtgca cggctgcacg cgctgctgtg gacggcgggc cccgggcgcc gcgcgatcag
     4201 cagtgcggtc ctgggcggag gcatcggccg gcgggcgtgg atcctcaacg cgcaggtgtc
     4261 gcacggctac cggcgcaccg accccgaacg gcacctcgcc tgcctcgccg ccgacgcggg
     4321 cctgagcggg cccggggtgg gtctgatgac ggcggccgac gtgtcggcgt acgcgcacgc
     4381 gcgcgacggg ggcgtggagg cgttcgtcac agcgggcgtg gacgtgcgcg actgggcggc
     4441 gcggcccggt gagggcgccg agggggcccc ggagccgggc acgatcaacg tcgtggtggc
     4501 tgtgccggcc gcgctgaccg acgcggccct ggtgaacgcc gtggccaccg cgacggaggc
     4561 gaaggtacag gctctggtgg agagcggcca cgactgctcc ggcaccccga ccgacgcggt
     4621 gtgcgtggtc gccgacgccc cggccccgga ccgggaggcg tacgcgttcg ccgggccccg
     4681 gtcgctgtgg ggcgcgcggc tggcgcgtgc cgtgcaccgg gccgtgcggg acgccgtcgc
     4741 ggagggcgtg cccggcggtc ccggcacgtc cggtgtgacg catggaacac cagttccggg
     4801 gtactgagcg cctcatggcc cgcctcgccg agcaggcagg ttgcttcgca ggcacggatg
     4861 ggggaccgtg gccgccgtac ctgctgacgc cgacgagaaa gggggtgggt gcgcggcgcg
     4921 cacctcgttc gtgatctctt cccccggttc cagcgccgat ccgtgccatg cgcgcgacca
     4981 gtccgtcccc acgtgggacg acgcgccatg ccctgttctg gtactggact cccgcggccg
     5041 gatcgccggc cgcaaccgtg ccgcccgccg cctcaccgcg tcctcccgtg actccgacgt
     5101 cccgccgtcg tggctgggcg aggcgcaccg gagtcatgtc gccggcgccc tcgacccgac
     5161 ggcggccacg ccggccgggc tcctcggcga ccgctccttc gaggcccggc cctcccccac
     5221 cggggacggc catgtggcct ggtggctgtt cgaccgcacg gacctcgtgc gggcccagga
     5281 gaccgtgcgg gagacccgcg agcgggccga tgtcacctcc ggcctcttca gcaccctgct
     5341 gtcctccctg aacgtgccgc gctgcgcgga ggtggccgca ctgatggccg ccgaccacct
     5401 cgccgaggcc gccgtgctga tcaccccgcc cgccgggcac cggtacgccg tcacccacgc
     5461 cctgcgcggg cggcgggtgg tgcaggagac ccggcagatc gacccgctca ccgtccccgg
     5521 gctcgacgag gccctgcgcg gcttcccgcc cgtgccggcc cgctggatca acccggacgc
     5581 catcccggcc tgggcgatcc ccgacggctt ctccggtccg gtcggttccg tgctggtgac
     5641 gccgctgccc gggcacgggg tgcccgcggg cgcgctgatc ctgctgcgct cggacaccga
     5701 gaaggggttc acgcccgagg aggaggagtt cgcccggctg ttcgcctccc gcgcgggcac
     5761 cgccctctcg gcggcgcgcc tctacggcga gcagacggcc atcaccggca ccctgatgcg
     5821 ggagctgctg ccgccgccgc tgagccgtgt gcacggcgtc gactacgcgg gccgctaccg
     5881 caccgccatg gaccacgagc gggtcggagg cgacttctac gacgtccacc ccggccccga
     5941 cgggtccgcc gagacgttcg tggcgctggg cgacgtggcc ggcaaggggc tggacgcagc
     6001 ggtcctcacc gggaagatcc gcaacacgct gcacgcgctg ctgccgctgg cctccgatca
     6061 cctccgggtg ttgcgcatgc tgaacggcgc cctgctcacc tcgcaccacg cccggttcgc
     6121 caccctggtg ctggcgtccg tgaagcggca ggacgacggc ccggtgcggc tgcggctcac
     6181 cggcgccggg catctgccgc cgctggtggt gcgcgcggac ggccgggtcg aggagatgcc
     6241 cacgcagggc accctcgtgg gcgcgctgcc cgaggtgacg gcgcgcaccg tggagacggt
     6301 cctcggcccg ggcgacacct gcctgctcta cacggacggc atcaccgagg cccgcggtgg
     6361 cccgctgggc gacgaactgt tcggcgagga gcggctgcgg caggccctgg agggatgcgg
     6421 cggtatgccg ggcgaggcga tggtggaaca cgtacagatg ctggccgcgc agtggctgga
     6481 gccgggcagc cgccacgacg acatggccgt cgtggccatc accgccccgc ggaacggcgg
     6541 cccggcgggc gaccgcgcgc cggccggtgc cgacggatga cgagcacgga ggcaggcatg
     6601 agcggcggcc cccgggcctc ggccggcgaa ctcggcgagg cgttgtggaa ggcggtgatc
     6661 gacggcgacg agtacgacgc cgtcgacgtc gtccgcggcg ccctggccgg gggctggcag
     6721 gaggaggacc tgctgctgga cgtggtcgcg gcggtacagg ctcggatcgg cctggagtgg
     6781 gccgccgacc gcatcaccgt cgcccaggag cacgcggcga cggcgatcaa cgagcgggtg
     6841 atcaccgccc tggtgcacaa cggctccggc aggcgtcccg aggccgtccg gggccgggtc
     6901 acggtgagct gcgtcgacgg cgaatggcac gcgttccccg cgcgcctcgt cgccgagacg
     6961 ctgcggctgc gcggctggca ggtcgactac ctcggcgccc agacgccgac cccgcatctg
     7021 gtcgcgcacc agcaccacac caactccgac gccgtgctgc tctccggttc gatccccacg
     7081 cacctgccgc gggcgcacac cgcgatcaac gcctgccggt ccgtgggcgt gccggtggtg
     7141 gcgggcggcc gggcgttcgg cgtggacggg cggtacgcgc gggccctggg cgccgacgca
     7201 tgggccccgg acgcccgggg cgccgcggcc gtgctggagg ccgggctcgc gcgaccgacg
     7261 aacgtccggc aggccgtcga cgacctgccg cacctggccg accaggagta cagcatggtc
     7321 gtccggtcgc gcggccggct ggtcaaggag acgctggccg agctggagcg gcgcttcccg
     7381 ccgatgcggg agtacagcga cgcgcagcgg gagcgcacgg ccgaggatct ggcgcacgtc
     7441 gtcgacttcc tcgcgaccgc cctctacgtc gacgccgtcg aggtgttcac cgagttcctg
     7501 ggctggacgg cggacgtgct gtccgcgcgg aacgtccccc cgcactccct ggtgaccggc
     7561 ctggacatcc tcaccgaccg tctgcacgac ttcccgcgag tcctggccgt catccgcgcg
     7621 ggcgccgccc gtctcacgga caggaccgac ccggcggtca cggacacggt ggtctgaagc
     7681 ggggagcgcc ctcctgctcc cccccgctcc acgtcacccg cggcgcccca gcgctcccgc
     7741 cagcccgcgc agcaccgcgc tgcgtccgcg gtccgggacc gtccagaggg gctggccgcg
     7801 gacgccccag cgttccagca gggcgttggc ggcgagaaag ccggtggtcg ccgcgcgttc
     7861 catcagggcg accggcaggg aggtgcggac caggtcgccc gccaccatca ggcccgggtc
     7921 gggcgtgcgg accgtggggc ggtcctcgta tccgcccacg gggaagagcg ggcagtcggt
     7981 gccccactcg tggcgggcgt cgacgatccc ggccccgcgg gtctccgggt agatgcggtg
     8041 caactggtcg agcagccgct tctgttcgac ctccggtgcc gcctccgggg gcagggcgta
     8101 ggcgtgcagc tcgacgacgg agccgccggt gcgcgcggcc cagcgcgcgg cctcgtcctc
     8161 gtaccgttcg aggacgctca cgttgtcgag ggtgccgtag ccgccggtgc cgaggaagcc
     8221 gggccggtcg ggggcgaccg ggcggtccag ccagaggcgg gagaccagga acggcggggc
     8281 gttgcgcagc cgggcggtcc gctcccgcca gggggtgtcg ccgagcaggg gggagcggtc
     8341 gacgagggcg cggagtccga cggcgtccag ggcgagtacc acggtgtcgt ggcgccgcgc
     8401 ctcccggtcg gtggcgacct cgtacccgcc gtcgtccagg ggttcgacgt gctcgacggg
     8461 ggtggaggtg cgcaggtccg cgccgtgccg ctcgagcagg gcggcgagcg gttcccacag
     8521 ggccgtgggg aagggcgcgg tgggcacgtc gaacagcagg ccctcggagg agccgaggaa
     8581 gtagatgtgg aacatcagcg ccatctcggc cgccgacagc aggcgggggt cggcgaagaa
     8641 gctgcgggag aacacctcga aggccaggtg ccgggcgctc tccgggaagc ggaccgcgtc
     8701 gaggaagtcg tgcgcgctga ccgcgtcgag gcgtgcgtag atgtcgggca cgcggacgtc
     8761 gagcaggggc agcgcggccg ccgcgttcat ccggggcagg tcgcgcagcg ggaaggacgg
     8821 gctgagcgcg gcgaagccga tcgcgctcca cggcggggtg cggggcacgt gccggaagct
     8881 gtcgtgcatg ccgtcgctgt gccgcagcgg gtagtcgggc agcggggtga ggcgctccag
     8941 ggcggggtcg gtacggcgga gcaggccgcg caggttgtag tactgccgga agaaggcgtg
     9001 gaagccgcgg ctcatggtcg cgggcgtgcc gtcgccgagg tcgaccggcc agccgccgac
     9061 gcggccgccg aggtaggggc gggcctcgta gagggtgacg tcgacgccgc gttcggcgag
     9121 ggcggtggcg gcggccagtc cggcgatgcc gccgccgacg acggcggtgc tgggcctacg
     9181 gtcgccgtcg gcgcgcggcg cgcccggcgc gggcatgatc acgcgggcgc ggcggtcacg
     9241 gccgcggcgg gcggcggccg ggcggggcgg ccgggtcatc gcgcggtctc cgtcctggtg
     9301 gggcggcgcc cggtgaaggt gtgggtgatg ccggtctgcc agccgggcag cggcaggcgg
     9361 cgcacactgg tgaagccgtt cgcccgcagg cggtcggcga accggtcggc ggtgtcgaac
     9421 ccgacgacgc tgcgccacag atggcggtag aggtcgccgt ccccgagcag ggtcgcgacc
     9481 ggctggacga cgccccggca gaccagcgtc cacacggctc ggtcggtgcg gcggccgccg
     9541 agggtgtatt cgtgcacggc gagacgtccg ccgggcgcga gcaggccgtg cacggtgcgc
     9601 agcacggcgt cggggtcggt gacgttgcgg aacaggtagg cggcgaagac cgcgtcgaag
     9661 ggcccggtga ccccggcctc ggcgagccgc tcggcgggcg cgtgggtgaa cgtgacgttc
     9721 ggcggccagg tcttggcggc ggcccgctcc agcatgccgg cggaggcgtc cacggcggtg
     9781 atgtcggcgc tcggcagcac ctcggcgagc gctccggtgg aggcgccggt gccacagccg
     9841 aggtcgagca cgcgcagccc ctcgccgccg cggggcaggc ccaggcggcg tgccgagcgg
     9901 cgcagatggg cgtggtagcc ggggttggcg gcgacgaggg tgtcgtagct gcgggccgcg
     9961 tggtcgaagg cggcggcgag gtgctcgtcg cgcaggaggg tcatggggtc tccggggtgg
    10021 caggggcggg gcacgtcggg gggttcaggg gccgttcgta ggggcggcgg ggcaggccgg
    10081 gcagttccag cgcggagcgg agcatcgggc cgaccggggc gtgcaggccg acggcgaggt
    10141 cctcgtggag gcgggtgtcg ccgtcgagga accgcagcag ccgccgcatg gggacgcggt
    10201 cgaacaggcg gcagaacagg gcgggtccgt cggcgcgccc gccggccagg gcgcgcagca
    10261 gcacggcgtc catggcccgg gagcgggccg agtgggcggg cggcggcacc ggacggcggc
    10321 cctcgcggat cgcggctgcg acggcgcggg tctggcgctg gaggccggcg aaggtgtagc
    10381 cggtggaggg gcgggtggcg ccgcctgccg cgccgatgcg gaacacggac tggccggtcc
    10441 ggcggggcat caccgcgtcg gtcatcggga tgacgcccgt ctcggtggac agcacctcga
    10501 ggtcgcccag ccggagcacg tcgtcggtgt agtggcgtac ggcggcctcg taggcgtcgc
    10561 gggtgagggg gcggggggag aactcggtgt actccaccag ggcgtcgtgc cggccgaggg
    10621 gcagcacgta gccgaaggac aggccgtcgg cgggctgcgg ggtgcggaag tccatgagtt
    10681 cggcggtgcc gggggcgaag gcgggccggg cggtgcgcac gaaccaaccg tggaagtgct
    10741 ggagcaacgt ggtgcgggcg gcgggcaggc tgccgggcgg gcgtgagtcg aacacccagc
    10801 gggcgcccac gacacggggg tcgccgtcgc ggtcgcgcag ccgcaccagc gctcccccgg
    10861 gcacgtcctc cacggtgtcg acggtgccct cgacacgccg aaccccgtcg tggccggcca
    10921 ggtcgcgggc gacgaggtgc tcgaagtcgt cggagcggat catcttgtag cgcagcggcg
    10981 cgatgtcccc gtcgatgggg cggcctcccc ggtcgcggac gcgcaggctc cgccaggacg
    11041 cggtgacggc ggcgtcgaag cggccggggc ccgcctccca gaagcaccag gtgcgtcgcg
    11101 gcggtcgcag cggcccgggc ggcgcgtcca gcaggaccac ggacggcgcc cggcgcccgc
    11161 tgccgggacc ggccagccgg tgggcgaggg acagcccggc cgcccccgcc ccgacgatcg
    11221 cgacgtccgc ctccagcacg ccggcaccac cctcctcggt acgagtccgt gcggatccgc
    11281 acggccggtt gtcttcgtcc gtgtgcccgc gcggatccgg gtcactcgga cgtgagacga
    11341 cgggcgcgac cgggaaggca tgcgccggtc gtccggcgta ccggaacgat gcgcgtgccg
    11401 acgagaggaa gacaccggat gctcccgact ggggccaaga gacaccgcgc gacgatgccg
    11461 tcgcgcgcgc cgcgcccggc ccgtccgccc ggacccaccg tccgggtgcg gtccgtccgg
    11521 gtgccgtccg tgagcgtgac ggcggacacc gtgtgcgggt gcgcggcagg agcgggggcc
    11581 gggcggtgac ccgtaccgtt ccggggcgca cggaccatgt cgtcgtcgtg ggagccggcc
    11641 tcgccggtct gtcggcggcg ctgcacctgc tgggcgcggg ccggcgcgtc accgtcgtcg
    11701 agcgggacgg gctgccgggc gggcgcgccg ggcggctgga gctggacggg taccggatcg
    11761 acaccgggcc caccgtgctg accatgcccg acctggcgga cgagccgttc gccgcggtcg
    11821 gcgacagtct gcgcaagcgg gtcgagctgg taccgctgca ccccgcctac cgtgcgcggt
    11881 tcgccgacgg cagcagcctc gacgtgcaca cccgggcgga gccgatggcc gccgaggtgg
    11941 agcggttcgc cggggcaagg gaggcggcgg gctacctgcg gatgcgggag tggctggaac
    12001 ggctgtaccg ggcacagatg cgccggttca tcgacgcgaa cttcgactcg ccgctcggcc
    12061 tgctccatcc cgacctggcg cggctggcgg cgctgggcgg cttcgggcgg ttggacgccc
    12121 gcatcgggag cttcctgaag gacgagcggc tgcgccgggt cttctccttc caggcgctgt
    12181 acgcgggcgt gccgccggcg cgggcgctgg ccgcgtacgc ggtgatcgcc tacatggaca
    12241 ccgtcgccgg ggtgtacttc ccgcgcggcg ggatgcacgc gttgccgcag gcgatggcgg
    12301 acgccgccgc cgacgcgggc gcggacctgc gcttcgggcg ggaggtgacc cggctggagc
    12361 gttccggcgg ccgggtgacg gcggtggtcg cgggcgagga gcggatcccc tgcgacgcgg
    12421 tcgtcctcac gcccgacctc cccgtcacgt accgtctgct gggcggggcg ccccgccgtc
    12481 cggtgcggct gaggcactcg ccgtcggcgg tggtgctgca tctgggcacc gaccggacct
    12541 ggcccgaact ggcgcaccac acgatctcct tcggtgaggc gtggcgcggg acgttcgacg
    12601 agctgacccg ggccgggcgg ctgatgagcg acccgtcgct gctgatcacc cggcccaccg
    12661 ccaccgaccc gtccctcgcg ccgccgggcc gccatctgca ctacgtcctc gcgccctgcc
    12721 cgaacaccga catcgggccg ggcgccgccg agtggacgga cctggcgccg cgctaccggg
    12781 acactgtgct gcggacgctg gaggggcgcg gtctgaccgg gctggcctcc gcgatcgaga
    12841 cggagtgcgt ggtcacgccc gccgactgga ccgcgcaggg gcacgcggcc ggtacgccgt
    12901 tcgccaccgc ccacaccttc gcccagacgg gcccgttccg gccccgcaac ctggtgcgct
    12961 ccgccgggaa cgcggtgctg gccggctgcg gcaccacccc cggcgtcggc gtgccgaccg
    13021 tgctgctgtc cgggaagctg gcagcggcgc gcatcaccgg cgccggcggc cccgtcggac
    13081 gcgcgtccac ctcgtcttcc gcccaggagg ccctgcatga ccgagcgtga actggacgcg
    13141 gcggggatca ccgatccggt gctccgcgag gcgtacgacc actgccggcg gctcaacgcc
    13201 cggcacggcc ggacgtactt cctcgccacc cggctgctgc ccgtggagcg gcggcccgcc
    13261 gtgcacgcgc tgtacggctt cgcccgctgg gcggacgaca tcgtcgacgc gctcggcacc
    13321 ggcgcggaca ccgcccgccg ggacgccgaa ctggcggcgc tggaacggga gctggccaag
    13381 gggctgcggg acggggagag cgccgagccg gtggtgcggg cgctcgccga cacggcccgg
    13441 cggtacggca tcgaccacgc ccacttcgcc gacttcatga ccgccatgcg gtccgacctg
    13501 gtggtcaccg actacgccga ctacgcggcc ctgcggcggt acatgcacgg gtcggcggcg
    13561 gtgatcgggc tgcagatgct gcccgtcctc ggcacggtca ccgaccgcgg tacggccgcc
    13621 ccgcacgcgg cggccctcgg cgtcgccttc cagctgacca acttcctgcg ggacgtggga
    13681 gaggacctgg accgggggcg ggtgtacctg ccggccgatc tgctcgccgc gcacggtgtc
    13741 gaccgggagc ggctgcggtg gagccgggac acgggccgcc gtgacccgcg catcacctcg
    13801 gcgctgcgcg cgttcgagcg gctgacgcgg ggcgtgtacc ggcaggcggc cccgggcctc
    13861 gcgatgctcg aaccggtgtc ccgcccctgc atccgcaccg ctttcgtgct gtacggcgga
    13921 atcctggacg cggtcgccga ggacgggtac gcggtgctgc accggcggtc ggtggtgccg
    13981 cgcaggcggc gcgccgtggt ggccgcggac gggctggccc gggtggccgc ggcgcggctg
    14041 cgggcccggt cggccgccgc ccgtggaacc gaacgggctc cgctgacggc gccggagccg
    14101 gtggagccgc ggatggtcga ggaggtcgcg tgatggcggg tgacggacga cggcggcggc
    14161 tgccgctctc cctgcgccgc aacgcggtgg cgtgggaacg gcagcgcccc acctggcggg
    14221 acgccaagcc cgccctgatc gccggcgcgt tgaagcgggc gcaggcccgc ccgtcgggca
    14281 actggtacgt cgtggggtcc tcccgcgacg tcggcggcga ccgtccgctg ggccggacgg
    14341 tcgcgggaca ggaagtggtg gtctggcgcg acacgggcgg ccgcgtcgtc gccgggccgg
    14401 gtgtgtgccc gcatctgggc gcgccgctgc gggacagccc ggtgcgctgc ggcacgctcg
    14461 tctgccactg gcacggactg tccctggacg gcgggccgtt cgccggctgg gagccgttcc
    14521 ccgcgtacga cgacggggtg ctggtgtggg tacggctgga cgcggtgggc ggcgaggagc
    14581 cgctcgacgc gccggtggtg ccgagccgcc cggtgccggc gcgcgccctg acggcggtgt
    14641 acgcgggcgt gggcgtctgc gagccggagg acgtcatggc gaaccggctc gacccctggc
    14701 acggggcctg gttccacccg tactcgttcg tcgacctcac ggtggcggac acgccggaga
    14761 gcgcgggcga ggacgcgttc gccgtggacg tgtcgttcaa ggtggcgggc cgcctggtgg
    14821 taccggtccg ggcggtcttc acggctccgg agccgcgcac ggtcgtcatg cacatcacgg
    14881 agggcgaggg ggtcggctcc gtggtcgaga cgcacgccac tcccctgggc ccggacgcct
    14941 ccggccggcc gcgcacggcg gtggtcgagg cggtggtcgc ggcctcggac cgccgcggct
    15001 tcgccctggc ccgagccgcg gcgcccgtcc tgcgccccct ggtccgcgcc gcctccggcc
    15061 gcctgtggcg tgacgacctg gcctacgcgg aacgccgctg ggcgctccgc tcgacgggac
    15121 ggttcccggg ggcgtgaccg tccggcccgc ccggtgagga caccgtccgg gccggacgac
    15181 ggcggcttcg ccgcgcgagc gagcggcggc ctggtccggc tgacggcgcc gggccggggc
    15241 cccgaggatt ccggtgcaca gggtcgacgg gcgagggagc cacgccgaac gaagcgccac
    15301 gccgaccggg ggatgtccgc ccttcggccc gcgccggcac cctgctgtgc atccgcccga
    15361 cggcggggcc cagtccctcc agctccggtc gttcagcccg gagcccactc ggcactcgcc
    15421 ggcggagggg acgggtcgcg cgggtgggcc gcggaccgtg cgcctccgct cggtcgggca
    15481 ggcgccacgg tgtcccgcgc gaccccggcg agcggcgcgc cggcgcctcg ccccgcaccc
    15541 ggggcgccca cggcgcggtg cgggccctgt ccacggggcc gcccgcgccg cgcacgtcag
    15601 agccgtaccg gcccgggcgg cgcgccgaga ccgcgtctca gctcggcctc gccgcctccg
    15661 agtccgccct gccgcctccg cccaggaggt ccgtgtgggt cagggaggaa cgcgcctcga
    15721 tgcgggggag gtagtggcgg gtcgccctgg tgaccacggc cggcatggcg gcccgtaccg
    15781 gctgggcgag gcggagccag cgcgggtagt agaccgccgt gctgcggcgt tccaccgcct
    15841 gggcgaggcg ggccgccgca cggtccggcg ggtacacgtc ccgcaccggc cacggcatgt
    15901 gcccccgcag ttcctgcatc acgccgtggc ggtcggcgtc ctcgatcagg tcggtgcgga
    15961 tccaggtgag gtagccgaga ccgacggtca cgccgaggtg ggcgacctcc gcgcgcaggg
    16021 agtgggcgaa ggcctccgca cccgccttgg aggcgcagta cgcgctcatc atcggggcgg
    16081 cgccgatggc cgcgagagag gcgacctgga ggtaatggcc cttggccgcc gtgaggtcgg
    16141 gcaggaaggt gcgggcggtg ttcgcgctgc cggtgaggtt gacgtcgacg atccgccccc
    16201 accgcgccgg gtcggagtcg gcgaacggcc cggcgtccgc cacggccgcg ttggcgacga
    16261 cgacggacgg tgtgccgagc ccggtccgta ccgcgtccgc cgcctgctcc agcgccacgt
    16321 cgtccgtgac atcgacctcg tacgcgaggg cgggggcggg caggtcgtcg gcgagctgcc
    16381 gcagccggtc gccctcgtgg ccgagcagcg ccacccgcat gccgcgtgcg gcgagttcgc
    16441 gggcgaggcc ggcaccgatg ccgcgtgcgg cccccgtgac cacggcggtg cgtccgccca
    16501 gcgggccgtc gctcatcccc cgtccccgcc ggtgatctgc gggtcgacgt ccgggcgggc
    16561 ggtgtggtgc gggtgacccg cggtcctgcg ggcctccttc atctccgcct cgaagaggtg
    16621 gtcgcggccg tcggccagct cctccaccgc ggcctgctcc agctcccgga acggccggta
    16681 gtacgtgtgg tcgtacgcct cgacgatctg gaacgtccag tggccgggga tgacgttgcg
    16741 gcccagcacc tgggtgcgga cggcctccgc ccagtccggg tgcccggcct tgtgcagcag
    16801 ttccacggcc cggtcgagct ccaggtcggc ggtaccggtg agctggtgga agctgtagag
    16861 gtggccgcgg gcccgttcgg tggtctccag tgccttcgac agcgatccca gcgcctcgac
    16921 cgtctcgtcg ctcaggccct cggggcgctg gtgccgacgg tcggggccgt cgtcgggccg
    16981 tccgttccgt ccgctcatcg tctcgcctcc ttctgaggtc ggtcgtccgt cgggccgggg
    17041 gtcggccgga cggggttcat gccgggcgcc cgccccggtc gggctgccgg tgtccggtgc
    17101 ggtcgcggtg ggccagcagc cgctgggcgg cggccagacc gggcgcgaag gacgggcgca
    17161 gcgcggcccg ggcggcgttg gcgccgggcg cgccgtgcac gccgccgccc gggtgggcgc
    17221 cggcggaggc caggtacagg cccttgacgg gggcctcggg acgcccggtg ccgggggccg
    17281 gccggaagaa gagctgctgg tgcatggcgg cggtgccgcc gttgatggcg ccgccgtgca
    17341 ggttgcggtc gaggttctgg agcgtgggcg gggcgaggat ccgccgggcc cggacgcggt
    17401 cgcggaagcc gggcgcgaag cgctccacat gggcctcgac gcggtcggcc atgcgttcct
    17461 gctcgtcctt gtcccaggag ccggtgatcc cgtcgtcgcc cgcgtccccg acgacccggt
    17521 gcgggacgtg ggtgtaggcc caggcggact cggtgcctgc cggggagcgg gtcgggtcgg
    17581 aggtggtcat ctgcccgaac agggagaacg ggcggtcggg cacccggccc atggcgagct
    17641 gggcggcgaa gcgggtgagt tcgtcgagcc cgtcggcgag gtgcacggtc ccggctcctg
    17701 cggcctgctc gcactgccac ggcaccggcc cgtccagcgc ccagtcgacc ttgaaggtgg
    17761 cgaagtccca ctggaagcgc tccaggtcgg acagcagttg ccggggcagg tcctcggggg
    17821 cgacgagttc gccgtagagg gcggggacgg acacgtcggc gaggacggca cgccgggcgg
    17881 ggacggtctc cccgtcggcg aggcgtacgg cgaccgcgcg cccgtcgcgg acgacgacgc
    17941 gttccacgtg ccgcccgcac cgcagcgctc ccccgcgtga ctccaggcgc cgcacgaggg
    18001 cgtcggtgag ggcgcccgcg ccgccgaccg gtacggggaa gccgtaggtc tgtccgagca
    18061 tggacatcag ccagccgaag ccgccgctgc cggcggcctc gggtgcgagg tcggcgtgca
    18121 gggcgttgcc cgcgagcagc agcccgccgc cctcgccgcg gaactcctcc tccgccatgc
    18181 gccgcacggg cagcacgagg gtgcgcgcca tgcgcagccc gccggtgccg cgcagccgta
    18241 cggcgagccg cagcccggag cggaccggcg ggaacggcgt gaacagggcg tccagcaggt
    18301 cgggacgcag ggtgtcccac atggagtaca gccggcgcca ggcgtcgccg tccccgggcg
    18361 cgaaggtgtc gagggagtcc gcggtgacgt cgacgtcgcg gtccaggatc gcgcagcggc
    18421 cgtcgctcag ggggtgggcg acgacgtgcg gggcgtggct ccagcgcagt ccgtgctcct
    18481 ccaggccgag cccggagacg accggggatg cggcggcgag cggatagaag gagctgaaca
    18541 ggtcgttggc gaagtcgggg tggacgccgt ggtcgtgacg cacggcgccg ccgggttcgg
    18601 gctgttcctc caggaccgtg acgctccagc cggcgtcggc gagcaggttc gccgcgacca
    18661 ggccgttggg ccccgcgccg atgacgacgg cgtcagccac gggcgcctcc cgcgtcgggc
    18721 tccggcggca cgatctggcc gagcggccgg cgctcctccg tctcggcggc ctcggtctcg
    18781 acgaggtgcg cgagccgggc gagcatggcg cggtggcgga tctggatgag cgcctcgact
    18841 cccacgttgt gcaggaagcc gcccgccccg cgcagggggt gttcgtccac cttgacgagg
    18901 caccagtcac cccacggctg cacctcgatg gcgatgcggg cggtgcccag cgggccggcg
    18961 ttggcctcca gttccagcac ctcgccgggg acgcagcgcc ggacgaccgt ctcgttgtgc
    19021 agcttcagcg gtccgacggg cacctcgtag cggatggcgg agccgagctg cggccagtgg
    19081 ccgtgcgccg gcttcgactc ggacgtcccc accacccagt ccgcgtagcg ggtgccgtcc
    19141 tccagcacgg accacaccgt ccgcgggtcg gtgcggatca agcgatgacg aaccgccact
    19201 gttgcctcct gtgtccctgg gcgccaccgg tcagctctga gtgccccgtc tgaccgccgt
    19261 caaccgagga ggcgcggccg gacgggtcag gcggctgggc gggtgggggc cagcgcccag
    19321 cggatgcccg cggtgacggc ggtgccgagc gggcggacgc acagggcttc ggcgggcatg
    19381 cggggcaccc gcagctcgcg ggacgcccac ggcggcagca gggacaccgc gttcgcggcg
    19441 aggacgccgt acggcaggcg ggcgagcagc gggacgggcg ggtcgagcag caggaaccgc
    19501 gcggtggcca gggcgtccgg ggtggcgtgc agctcgtcgc ggtaggcggc cagccgctcg
    19561 gcgagctgcg cccggttcac gggcgggtcg ggaacgccga gggcggtggc gatgcgcgcc
    19621 atgccggcga cgtacccgtc gcagccggcg tcgtccagcg ggcgggcgcc gtagcgctgg
    19681 tgggcgcgca ggaacatgtc gacctcggcg acgtgcaccc agcacagcag gtgcggatcg
    19741 gaggcgcggt actcccggcc gtcgggcgcg gtgccgcgga ccgtgtcgtg gacggcgcgc
    19801 acccggtcga cggcccgctg ggcgctgtcg gcggtgccgt acgtggtgac ggcgaggaag
    19861 gtgctggtcc gctggagccg gccccagggg tcgccgcgga agccggagtg ggcggcgacg
    19921 gcggccatgg cgagcgggtg gagcgactgg agcagcaggg cggacagacc gccgatgaac
    19981 atcgacgcgt cgccgtgcac ccggcggacc gggctctcgg gggcgaacca gcgggggccc
    20041 ggggtgccgt ggatgcgggc gcggttgtcc ggaccttcgg gtccggccac ccgcgagaag
    20101 atggcgtggc cgatgcggcc gcgcagtgcc gaggcgggtt cggcgatccg tttcatggtg
    20161 cgccgcacct ccctcggcgt tgacgttcta cggctacgtc tgccccggtc gccgcgtccc
    20221 tacccgcgca cggggctcgg tcacgggacg tcgccccgcc actcgtacac ccgggcgccg
    20281 gccgcgcggg gcgcgtagac cgcgcggccg ccggggccgt agcggcctat ctcggtgggc
    20341 aggcccacgc cgtgccgccg ctccgccggg ccgtggtcgg tgacgtccag cagcaggccg
    20401 tccagcgggc cgccggacag ctccgcgtac gtccgtccct cacgcggccc cgggtcgtcg
    20461 tggtccgccc cgtacacccg gccgcgcatg aactccgtct cgtccatgac ggcagggtgg
    20521 catccgccac tgacaacggc ccggtgcgcc cgcattagcg ggggaaaccg cgcgggcgac
    20581 cacgacggaa ttcgcggaca cgaaccgtcg ggaacgcccc tacgccgtct cctcccgcac
    20641 acccgcccac ggcgccagcg ccctcccctg gctccacgcc agcagcccgt ccccgtcgac
    20701 gcagacgatc ccgcactgct ccgcgtattc cagcgccggc acggtgaact cacccgtcgt
    20761 gacgacgacg gcgacatcgg cctcgtgcac cgtgaagcac gtgcccccga accgctgaag
    20821 atcctgcgag ccgaccttgt tgtcctcccc gtaccgcttg cactggacga cgagccggcg
    20881 tccgtccggc atcagggccg tcacgtcggc gccgagatcg cccgcaccgc ccaccacctg
    20941 gacctccgta cagccgtccc gcgcgcacag ctcggccgtg gccgcctcga actcgtccgg
    21001 tgtcagggcg tcgtggtcga tgccctgcgc cacgggcagc ggcgaggtga cctcgtccac
    21061 cggccccgcc tgggcgggga tgacgagcgg ggccggcgcc ggcgcgtcca gcgcgtcgag
    21121 cgccgtggag gtcccccggg cgaacgcgcg accggcctgc cgggccatcc ccgccgccga
    21181 cagccgcctc ctgcggcggc cgcgggccac ggcgacggcg aggaccaggc agagcagcac
    21241 gacggcccac accgggcgcc gctgcaccac cccggccagc gcgcgtaccg ccaggccccc
    21301 gatcaccagt gccgccgcga gcagaccgaa gaacatggcg gtggagcgca ggtcgaagcg
    21361 ccggcctggg cgcagcgcac gggtacgacg ctcgggcatg gtcaccgtgg tgactcctct
    21421 ctctggacgg ccgggcaccg gcgccccgca caccgggcac gccgaagatc acgaacgccg
    21481 tgtgcccccg atccgcgcgc tcaccagatc cgggtcgggc ggcctgtttc ggtgtccggc
    21541 gggaaagagg cgaccgtgag gagatgccac gatggtcagg agcacggccg gacggacagg
    21601 gagacggaca tggactggcg gcttttcgcc cagcgcatgg cgtcgatggc ccgggacctg
    21661 ctcgcggagc acacgctcga cgctacgctg gagcagatct cgcgctcggc ggtggagctc
    21721 gtggacggct gcgacgccgc gggaatcctc gtcctgagcc agggacgcgt acggtcgctg
    21781 gcgccgaccg acccgttcgt caccaagagc gacatgctgc agggcgagct gcgcgagggg
    21841 ccctgcttcg acgcggcacg gcccgaccgc ccggagcggc tgttccgcat ccccgacctc
    21901 acggcgcccc cggagcgctg gccgcgcttc gtgccccggg cccgggacct cggggtgggc
    21961 agcatgatgg gcttcctcct ctacacgcgg gaggaggaac tgggcgccct caacatgtac
    22021 tcgcgcaagc cggggatctt caccgaggac agcgagacgg cgggctggct gctggcgtcg
    22081 cacgcggcgg tcgcgttcgc caccgcccgc accgacgagc agatgcagga ggcgatcacc
    22141 acgcgccatc tgatcggcga ggcgatgggc atcctgatgg gccggcacga cgtcacggag
    22201 gaccaggcgt tcgagctgct gcgcacccgg tcgcagcgca ccaacaccaa gctgcgggac
    22261 gtggcgcggg agatctgcga gccgggcggc gcggagcgct gaccgcccgg ctcgtcgtac
    22321 ggcgcgcgct cagcggccgg cggtgccggt ccaggtgtgg gccacgtcga tcacgagacg
    22381 cccgtcgagc tgctgcacgc ggaacggcag ccgtccgcgc accccgagac cgagctgggt
    22441 gtcgccctcg aagctgccgg cgaaccgcgc gtcgcggaac gtgcggtacc cggtgaggtc
    22501 gacgcccggc aggacgcccc cggcgcgcgc gggataggtg gccgcgcccg tctccgggtc
    22561 gtaagcgggg gcggtgacgc ggacctcgag gatcgcgccg ccggagacgg ggatgtgccg
    22621 tcccgagccg tcctggagga gccggtcgac gtagcggacg gagtaaccga ggtcaccgcg
    22681 cgcggctccg ggcacgtcga cgaccatgcg gtcgtagcag tcgtgccggc cggtgcggac
    22741 gttccgcacg gactcggacg tggcggcggc ggccgccttg tcggtggagc cccagccggt
    22801 ggggcaggcc gtggccgcgg cgggcgccgc ctcgggggcg gccacggccg gaacggccgc
    22861 cgtcaccagc gaggcaccga ggagcaccac cgtcgcgcag attgttcttg gttgaagcat
    22921 tttcggcccc ctgggacgac aacgttctgt tatggggtga gacgagcggg atgacctgat
    22981 ggttgcggtg cgttcggccg gtcgccgtac cggcgcgcat ggcacatgct ggtgggaagc
    23041 ggacgaacgt cccgttccgt gcgcaccggg agggcgtcac atgggtggtg cagccgccgc
    23101 accgcgcggg cagcggccgg cgggcccgcc cgtacccgac gcggatgaga gccggtcccc
    23161 gcgcggcgag gcccgtatcg aggacgcgct cgcggacccc gtggtggcgg ccgtacggga
    23221 caccgggggg tacggcgggg cggtgtacct gcggtcgcgg gaccgccggt cgctggtgct
    23281 gagcgtgatg tccggcgtgc cccgctcgct gctgaagccg tggtggcgga tcccggtgag
    23341 cggcgcgctg ccgatgtgcg aggcgttccg cagcggcgag acgcagtacc tgcccgacga
    23401 ccgggcgacg atgctgcgct tcccgcagtt cacggccgcc ctgccgtact cgttcgcgca
    23461 cgcctaccag ccggtgcggg tcggcggcga gacggtgggt gtgctcgcgg tgctgcactc
    23521 ctcgttcagg gaaccggccg gtgaggcgga ggtccgggag gggctgcgcc gggccgtgca
    23581 ggagatggag gagcgcctcg ccgcgtacgc gcacggcctt ccgggccgca cggacgcgga
    23641 cgcggtggcg tacggcatcg agtacgacga ccagccggtc agcgtgcggc tgccggcacc
    23701 gcgcgccgag gcggtcgcgg tcgggatggt cgagtgggac ctggccggcg gtcgctggac
    23761 gggggacgac gacgcgctgg agctgctggg cgtgtcccgg ggcgagttcg gcggcaccct
    23821 ggccgcggtc gaggaacggg tgtcgccgga cgacctgtac gagctgcggg cggcccgccg
    23881 ggacgcggag gagaccgggc aggtccgggg ccgccacttc cgggtgctgg acgcgtcgca
    23941 ggacgacagc gaggcggtcc gctaccggcc ggtggagctg tgggggcacg tggtccggac
    24001 ggggacctcc gaccggctgc tggtgggcgc cctggtcgac gtggcgggcg gcgtcaccgc
    24061 ggcggaggcg gccgagcggc tgcccgacgg gctgttctcc ctcgaccagg acggcagggt
    24121 catctacgcc aac
//
