LOCUS       NZ_BMTZ01000004        21122 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces variabilis strain JCM 4422 sequence04, whole genome
            shotgun sequence.
ACCESSION   NZ_BMTZ01000004
VERSION     NZ_BMTZ01000004.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces variabilis
  ORGANISM  Streptomyces variabilis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces griseoincarnatus
            group.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 431607)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: BGI assembly pipeline
            Genome Coverage                   :: 156X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014649935.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:37:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,743
            CDSs (total)                      :: 6,668
            Genes (coding)                    :: 6,496
            CDSs (with protein)               :: 6,496
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 172
            CDSs (without protein)            :: 172
            Pseudo Genes (ambiguous residues) :: 0 of 172
            Pseudo Genes (frameshifted)       :: 61 of 172
            Pseudo Genes (incomplete)         :: 147 of 172
            Pseudo Genes (internal stop)      :: 11 of 172
            Pseudo Genes (multiple problems)  :: 42 of 172
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:23:51
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 172465
            Orig. end                         :: 193587
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMTZ01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21122
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21122
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21122
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11122](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11122)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(1071..2306)
                     /locus_tag="IE148_RS09205"
                     /old_locus_tag="GCM10010287_18450"
     CDS             complement(1071..2306)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003997977.1"
                     /locus_tag="IE148_RS09205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_18450"
                     /product="NADP-dependent malic enzyme"
                     /protein_id="WP_048455672.1"
                     /transl_table=11
                     /translation="MAAEIVNPRSDSENRDASERDGGAEPLESFDPAFALHRGGKMAVQ
                     ATVPVRDKDDLSLAYTPGVAKVCSAIAEQPELVHDYTWKSSVVAVVTDGTAVLGLGDIG
                     PEASLPVMEGKAILFKQFGGVDAVPLALNCTDVDEIVETVVRLAPSFGGVNLEDISAPR
                     CFEIERRLQERLDIPVFHDDQHGTAVVTLAALRNAARLSGRPLGELRAVISGAGAAGVA
                     IAKMLVEAGIGDVAVADRKGVVSRDREDLTPIKAELASFTNKAGISGTLESALAGADVF
                     IGVSGGTVPEPAVASMAEGAFVFAMANPNPEVHPEVAHKYAAVVATGRSDFPNQINNVL
                     AFPGIFAGALQVRASRITEGMKLAAAEALAAVVGDDLAADYVIPSPFDERVAPAVTAAV
                     AAAARAEGVARR"
     misc_feature    2329..2338
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.55"
                     /tool="antismash"
     misc_feature    complement(2545..2560)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.33"
                     /tool="antismash"
     misc_feature    2794..2809
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.33"
                     /tool="antismash"
     gene            2887..3852
                     /locus_tag="IE148_RS09210"
                     /old_locus_tag="GCM10010287_18460"
     CDS             2887..3852
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061477.1"
                     /locus_tag="IE148_RS09210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_18460"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_189364228.1"
                     /transl_table=11
                     /translation="MTASTTRRTTAARSRIAAVGAIAVAGALLLTGCGDQTEGSGGSDT
                     KGSGKTNSAPLFDKLPKDIQDAGVLKAGTNAEYAPMEFQEGGKIVGVDPDIAAALGEKL
                     GVEVEFTSGNFDGLITALNSGRYDIAMSSITDNKQRQEGLDDKGKKLGPGVDFVDYFVA
                     GTAVYVQKGNPKGINSIEDLCGQPAAVQRGTTYEKALQDQSKKCTDAGKKAIKIQPFEN
                     DTEAQTRVKSGGAVAGVNDYPVAVDLVRKADNGNAFEIVGEQVDAGPFGIAVNKDNKQL
                     TEALEAAVNAIIEDGTYKKILEKWGAETGAIDKAVINGGK"
     gene            3884..4855
                     /locus_tag="IE148_RS09215"
                     /old_locus_tag="GCM10010287_18470"
     CDS             3884..4855
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019522924.1"
                     /locus_tag="IE148_RS09215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_18470"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_122213537.1"
                     /transl_table=11
                     /translation="MTDKLDKGTDGARPAATVSKDEGPAPVAPAVIKAIPVRHYGRYVS
                     AVVVLALVGLLINAFATAEKIQWQAVGDYVFDGTVLAGAGRTLLISVLAMVMGVVLGVV
                     LAVMRMSKNPVTSWVAWAYIWFFRGTPVYVQLLLWFNLALIFPVLNLGPLYKDEMVDVM
                     TPFMAALLGLGLNEAAYMAEICRAGLQSVDDGQTEAAHALGMSHGKTLRRIVIPQAMRV
                     IVPPTGNEFLNMLKTSSLVYAVTYNELLRATSTIGSTSYAVMEMLFVACVWYLVITSVF
                     SVGQYYLERRFARGSSRNLPATPWQKIKANMMAFSRERSSTV"
     gene            4852..5613
                     /locus_tag="IE148_RS09220"
                     /old_locus_tag="GCM10010287_18480"
     CDS             4852..5613
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973712.1"
                     /locus_tag="IE148_RS09220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_18480"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_048455675.1"
                     /transl_table=11
                     /translation="MTAMVKAEGVHKSFGGVQVLKGIDLEVEQGEVFCLIGPSGSGKST
                     FLRCINHLEKINAGRLYVDGELVGYRQKGDKLYELKDSEVAQQRRDIGMVFQRFNLFPH
                     MTAVENVMEAPVQVKGLNRSAARQRALELLDRVGLGDKAGNYPSQLSGGQQQRVAIARA
                     LAMDPKLMLFDEPTSALDPELVGDVLDVMRDLAESGMTMIVVTHEMGFAREVGDSLVFM
                     DGGVVVESGHPREVLTDPQHERTKSFLSKVL"
     gene            complement(5685..6455)
                     /locus_tag="IE148_RS09225"
                     /old_locus_tag="GCM10010287_18490"
     CDS             complement(5685..6455)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983528.1"
                     /locus_tag="IE148_RS09225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_18490"
                     /product="trans-aconitate 2-methyltransferase"
                     /protein_id="WP_189364229.1"
                     /transl_table=11
                     /translation="MTDSHTTTAGADWQAWQESWDRQQEWYMPDREERFRVMLDMVEAL
                     VGTAPRVLDLACGTGSITARLLDRFPEATSTGVDLDPALLAIAEGTFAGDERVTFVTAD
                     LKDPGWATQLPHDSYDAVLTATALHWLHREPLADLYGHLAGLVREGGVFMNADHMIDET
                     TPRINAAERAQRHAHMDRAKERGALDWSEWWQLAAKDPVLAGPTARRFEIYGEHADGDM
                     PSPAWHARVLREAGFAEARPVWCSPSDTLLLALK"
     misc_feature    complement(6547..6562)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.99"
                     /tool="antismash"
     gene            6555..7205
                     /locus_tag="IE148_RS09230"
                     /old_locus_tag="GCM10010287_18500"
     CDS             6555..7205
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004925775.1"
                     /locus_tag="IE148_RS09230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_18500"
                     /product="ABATE domain-containing protein"
                     /protein_id="WP_122213535.1"
                     /transl_table=11
                     /translation="MELAYYSDYAVRLVNTEEPVRGTDVLTSVEAVRDLFGGNRSAARR
                     ATEADVTRFRSVRARLRSVFAAADDGDETLAVDLLNSLLLEFPVSPQISGHDFRDDDGR
                     PLWHMHLADHPSNATAGYAAIAAMGLAFHLTEYGVDRLGLCEAAPCRNAYLDTSTNRSR
                     RYCSDRCATRANVAAYRARKRLEADRSESTGRADVSSQTSSPSGDRRAVERGR"
     gene            complement(7088..7522)
                     /gene="sodX"
                     /locus_tag="IE148_RS09235"
                     /old_locus_tag="GCM10010287_18510"
     CDS             complement(7088..7522)
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016485 - protein processing [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004925778.1"
                     /locus_tag="IE148_RS09235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_18510"
                     /product="nickel-type superoxide dismutase maturation
                     protease"
                     /protein_id="WP_078894965.1"
                     /transl_table=11
                     /translation="MPELSQDAERVRAPLPFGVAEVTGPSMVPTLRHGDRLLVHYGARV
                     RRGDVIVLRHPFQQDLLVVKRAAERRDGGWWVLGDNAYAGGDSTDYGVVPDELVLGRVR
                     FRYRPRSTARRSPLGLLVWLLTSARPVLSDRSASRRLRAR"
     gene            7669..8064
                     /gene="sodN"
                     /locus_tag="IE148_RS09240"
                     /old_locus_tag="GCM10010287_18520"
     CDS             7669..8064
                     /EC_number="1.15.1.1"
                     /GO_function="GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016151 - nickel cation binding [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313646.1"
                     /locus_tag="IE148_RS09240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_18520"
                     /product="superoxide dismutase, Ni"
                     /protein_id="WP_086701670.1"
                     /transl_table=11
                     /translation="MLSRLFAPTVKVSAHCDLPCGVYDPAQARIEAESVKAVQEKMAGN
                     DDPHFQARATVIKEQRAELAKHHVSVLWSDYFKPPHFEKYPELHQLVNDTLKALSAAKG
                     STDPATGQKALDYIAQIDKIFWETKKA"
     gene            8211..8633
                     /locus_tag="IE148_RS09245"
                     /old_locus_tag="GCM10010287_18530"
     CDS             8211..8633
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006136257.1"
                     /locus_tag="IE148_RS09245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_18530"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_086701672.1"
                     /transl_table=11
                     /translation="MELEDLVRLRRARDRMDREYAEPLDVAELARTALMSPGHFQRSFR
                     AAYGQTPYAYLMTRRIERAKALLRKGDLSVTEVCLAVGCTSLGSFSSRFTELVGETPSA
                     YRARSHEESAVIPPCVVRTYTRPVRVRRRVDPSGNS"
     misc_feature    complement(8218..8232)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.31"
                     /tool="antismash"
     misc_feature    8219..8233
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: strong, score: 21.15"
                     /tool="antismash"
     gene            8650..9075
                     /locus_tag="IE148_RS09250"
                     /old_locus_tag="GCM10010287_18540"
     CDS             8650..9075
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019522918.1"
                     /locus_tag="IE148_RS09250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_18540"
                     /product="VOC family protein"
                     /protein_id="WP_086701673.1"
                     /transl_table=11
                     /translation="MDRATDVRLAQCFVAVDDHDKALAFYCDVLGFEVRNDVGFEGMRW
                     VTVASPEQDVEIVLEPPAASPDISPADKQAMAELLAKGVLRGVNFTTTDCDALFERVRA
                     AGVDVLQEPVDQPYGMRDCAFRDPAGNMVRFLERPAD"
     gene            complement(9180..9803)
                     /locus_tag="IE148_RS09255"
                     /old_locus_tag="GCM10010287_18550"
     CDS             complement(9180..9803)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019522913.1"
                     /locus_tag="IE148_RS09255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_18550"
                     /product="N-acetyltransferase"
                     /protein_id="WP_189364230.1"
                     /transl_table=11
                     /translation="MGVAIRTAGGDDRELVVRLLDEAFQDDPVSSWVFPGAEYRRVTHH
                     RLMAAFTDATLADGRVDLVEDGSACALWMSVPAGDPGHGGADGGDDEFAALRHAVDPDN
                     ERVEMIGRLTAGIHPQGRAHEYLWMIGVAPGRQGEGLGTALIGSVLDRCDREGRAAYLE
                     ASSERSVRLYRRLGFELTGEPLRLPGGPLMYPMWREPRAAGAQA"
     gene            complement(10001..11122)
                     /locus_tag="IE148_RS09260"
                     /old_locus_tag="GCM10010287_18560"
     CDS             complement(10001..11122)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019522912.1"
                     /locus_tag="IE148_RS09260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_18560"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_086701676.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.6e-62, bitscore:
                     205.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTESMARPTTGRPEQRTARTAPDSTPGPDPHAGDGHEAAALLERT
                     RAAVDPVLRTALGSLPAPLRRLALYHFGWQNADGTPAAGGSGKALRPALVLAAASALGG
                     SAARTAALRAAAAVELVHNFTLVHDDVMDRDTTRRHRPTVWTVFGDADAILLGDALQAL
                     ALRLLAEDPHPAAPAAAARLTQCVVELCAGQHADTAMERRAPDEVTLEETLAMAEAKTG
                     ALLGCACALGALYADAGDEEVAAMDAFGREAGLAFQLIDDVIGTWGDPRRTGKPAGADL
                     AARKKSLPVVAALTSGTPEAAELAAAYAAPHQKEEVEELTRLVERAGGRDWAQTQAADR
                     MARAMQEVARAVPDPEAAGGLLALAEFVTRRTT"
     gene            complement(11256..12662)
                     /locus_tag="IE148_RS09265"
                     /old_locus_tag="GCM10010287_18570"
     CDS             complement(11256..12662)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136651.1"
                     /locus_tag="IE148_RS09265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_18570"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_122213533.1"
                     /transl_table=11
                     /translation="MSVGEEVRTEQTRQQQSLGTAAARNLATTTKSVPQMQEISSRWLL
                     RMLPWVDVQGGTYRVNRRLTYAVGDGRLTFVKTGDRVEIIPAELGELPVLRDYEDEEVL
                     SELASRCRQREIEAGQVIASFGSPADEVYLLAHGRVERVGTGPYGEDESLGVLADGAYF
                     GEQALQDDDAIWEYTARTLTACTVLVLPRDAVDQVAERSETLREHLRRRADIPQQPTNK
                     YGEKEIDLAAGHSGEPDIPHTFVDYEARPREYELSVAQTVLRIHTRVADLYNQPMNQTE
                     QQIRLTVEALKERQEHELINNRDFGLLHNCEYDQRIQPHDGVPGPDDMDELLSRRRGTR
                     LLLAHPRAIAAFGRELNKRGLVPETVDVGGNRIPTWRGVPIYPCNKIPVTEARTTSIIA
                     LRTGEEDQGVIGLRAAGIPDEIEPSLSVRFMGINEQAIIKYLVTAYYSAAVLVPDALGV
                     LENVEIGRWR"
     gene            12973..13554
                     /locus_tag="IE148_RS09270"
                     /old_locus_tag="GCM10010287_18580"
     CDS             12973..13554
                     /EC_number="3.5.1.28"
                     /GO_function="GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA]"
                     /GO_process="GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030135.1"
                     /locus_tag="IE148_RS09270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_18580"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_114874777.1"
                     /transl_table=11
                     /translation="MSASAFLRALKAEGLTVVEVGDWRDHNRNHKGPWGPVHGVMIHHT
                     VTKGSKATVDICRKGYSGLPGPLCHGVITKDGRVHLVGYGRANHAGLGDDDVLRAVIAE
                     KKTFPPDNEANTDGNRHFYGFECENLGDGKDPWPAAQLEAVEKAAAAVCRHHGWNEQSV
                     IGHLEWQPGKVDPRGFTMASMRKRIRDRLK"
     gene            13683..14585
                     /locus_tag="IE148_RS09275"
                     /old_locus_tag="GCM10010287_18590"
     CDS             13683..14585
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016824664.1"
                     /locus_tag="IE148_RS09275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_18590"
                     /product="1-aminocyclopropane-1-carboxylate
                     deaminase/D-cysteine desulfhydrase"
                     /protein_id="WP_189364232.1"
                     /sec_met_domain="PALP (E-value: 5.8e-18, bitscore: 59.9,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSSDALAGLRPRLPSPLEEAVDARFERHGVRLLLKRDDLVHPEL
                     VGNKWRKLAPNLAAAGGRTVLTFGGAYSGHLRATAAAGRLLGLRTVGVVRGEELADRPL
                     NPSLARCAADGMRLRFVARSVYRRKTDPDTLAAVLRAADAEDAHVVPEGGSNAAAVRGC
                     VELGRELAGAADVAAVACGTGGTLAGLAAGLAGSARTLGIPVLRGGFLAGEIRTLQTEA
                     FGGPRGAWSLDERFHHGGYARVPADLEAFAADFEQRHGVPVERIYVAKLLRALVTLAGE
                     GAFPRGSTVAAVITGRPFP"
     gene            complement(14610..16202)
                     /locus_tag="IE148_RS09280"
                     /old_locus_tag="GCM10010287_18600"
     CDS             complement(14610..16202)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006136264.1"
                     /locus_tag="IE148_RS09280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_18600"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_086701681.1"
                     /transl_table=11
                     /translation="MDVMPLLLLVAGSAAVAAAARRTPVPPPLVLVAVGLVVSYIPGVP
                     EYELDPHIVLPLILPPLLYTAAVDSSYLDLRAQLRPVALLSFGYVLFATLAVGWVLYLL
                     VPDLPLTAALVFGAVVAPPDAVAATAVARRVGLPSRITTILQGESLFNDATAITAFRVA
                     VAASVGEGVSWAGGVGEFLLAAVGGVAVGLVLMAPLHWLRTHLRETLLQNTLSLLIPFV
                     AYAVAEQVHASGVIAVVVVALYLGHRAWEVDFATRLQEGAVWGMVAFVLESAVFALIGL
                     QLPVVMRGLGEHEGIASAWYAVAVFAVVVAVRFLWVYPAVWLPWLVSARIRARERRPGW
                     KGPFVISWAGMRGVVSLAIAFSIPVTAEGEDFPHRYLLLFLTFTTVIGTLVVQGLTLPP
                     LIRLLRLPGRDPRGETLAEANAQAQASRAAEERLDALLADERNALPAPLADRLRSVLER
                     RRNAVWERLGQVNPVTGESVDDTYRRLSREMIGAEREVFVKLRDARYIDDEMLRTLLRR
                     LDLEEAAAYREAD"
     gene            16263..16523
                     /locus_tag="IE148_RS09285"
                     /old_locus_tag="GCM10010287_18610"
     CDS             16263..16523
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571357.1"
                     /locus_tag="IE148_RS09285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_18610"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_048455686.1"
                     /transl_table=11
                     /translation="MKQCTHVEALPHPEPAALDETCPECLREGTDPVQLRLCLTCGHVG
                     CCDSSPNRHAARHHRETGHPVMRTFEPGEDWRWCFVDHVLV"
     misc_feature    complement(16642..16655)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.89"
                     /tool="antismash"
     gene            16781..17194
                     /locus_tag="IE148_RS09290"
                     /old_locus_tag="GCM10010287_18620"
     CDS             16781..17194
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="IE148_RS09290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_18620"
                     /product="anti-sigma factor"
                     /protein_id="WP_006136266.1"
                     /transl_table=11
                     /translation="MSQIAGEPATQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLSCVFRLVDDSLEVTVSAPTTDGHAPSRDTFAWTV
                     LSALAGKVSSAVDEDRTVSISLYKQRGAGPGPA"
     gene            17212..18324
                     /locus_tag="IE148_RS09295"
                     /old_locus_tag="GCM10010287_18630"
     CDS             17212..18324
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019522906.1"
                     /locus_tag="IE148_RS09295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_18630"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_163080900.1"
                     /transl_table=11
                     /translation="MRDEERGTRELPAERVPDGIDGIPEQARPHPEDDSARGVGPGGGQ
                     AGGAVRDTSAAGPAAPGGEAPALAEPVAGDEASARGRATGGTMSEHEREAEEQAAPASG
                     ARSTPGVPGTHAHHDPQDRSGARALFLELRTLEDGTPEYAELRNRLVRMHLPLVEHLAR
                     RFRNRGEPLDDLTQVATIGLIKSVDRFDPERGVEFSTYATPTVVGEIKRHFRDKGWAVR
                     VPRRLQELRLALTTATAELSQLHGRSPTVHELAEKLAISEEEVLEGLESANAYSTLSLD
                     VPDTDDESPAVADTLGAEDEALEGVEYRESLKPLLEDLPPREKRILLLRFFGNMTQSQI
                     AQEVGISQMHVSRLLARTLAQLREKLLVEE"
     gene            complement(18341..18793)
                     /locus_tag="IE148_RS09300"
                     /old_locus_tag="GCM10010287_18640"
     CDS             complement(18341..18793)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006134763.1"
                     /locus_tag="IE148_RS09300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_18640"
                     /product="hypothetical protein"
                     /protein_id="WP_048455759.1"
                     /transl_table=11
                     /translation="MSSEQTPATSPDDTGARPRRLTYAAVLAALEGLALVVGGVWLLVL
                     GLAGEPDDRQQSVTGGVTLIVLALLPLLAARGLFARRSWSRGPAVITQIMALPVAYNML
                     TSDGVAIPAGIALAVVAVTALVLLINAETTRALGIRGPGNAGDAAQ"
     gene            18910..19878
                     /locus_tag="IE148_RS09305"
                     /old_locus_tag="GCM10010287_18650"
     CDS             18910..19878
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127486.1"
                     /locus_tag="IE148_RS09305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_18650"
                     /product="diacylglycerol kinase family protein"
                     /protein_id="WP_048455687.1"
                     /transl_table=11
                     /translation="MRALLVVNPAATTTSARTRDVLIHALASEMKLDAVTTEYRGHARD
                     LGRQAAESGEVDLVVALGGDGTVNEVVNGLLHAGPDPEHLPGLAVVPGGSTNVFARALG
                     LPNQPVEATGALLDALREGRERTVGLGLTSGTPGTEDEAVPARWFTFNAGLGFDAGVVG
                     RVEQQRERGRRSTHALYMRQVVRQLLGDPHRRNGVITLDLEGEEPVEDLVLSIVSNTSP
                     WTFLGNRPIYASPQASFDTGLDLFGLTRMSTPAVARYGTQLLTSSPERGPRGKHAVVRH
                     DLTRFTLHSKVPLPLQMDGDHLGLRTSVTFTGVRRALRVIV"
     misc_feature    complement(19963..19977)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.74"
                     /tool="antismash"
     misc_feature    complement(19968..19977)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.86"
                     /tool="antismash"
     misc_feature    complement(20139..20154)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     misc_feature    20142..20153
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     gene            20196..20453
                     /locus_tag="IE148_RS09310"
                     /old_locus_tag="GCM10010287_18660"
     CDS             20196..20453
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563321.1"
                     /locus_tag="IE148_RS09310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_18660"
                     /product="WhiB family transcriptional regulator"
                     /protein_id="WP_003992873.1"
                     /transl_table=11
                     /translation="MDWRHNAVCREEDPELFFPIGNTGPALLQIEEAKAVCRRCPVIEQ
                     CLQWALESGQDSGVWGGLSEDERRAMKRRAARNRARQASA"
ORIGIN
        1 atccgctcga agccctcgcg ggcccggtcc aggggcagta cctcgtcgat gacgggacgc
       61 accccggtcg cggcgcagaa ggacagcagg tcctccagct cgtccttggt gcccatggtg
      121 gagccgacga ccttcagctc caggaagaag atgcgggtca gctcggcgtg cgagggccgg
      181 tcgccactgg tggcgccgga gatcaccagc gtgccgccgg ggcgcagcga cttcaccgag
      241 tgggaccagg tggccgcgcc cacggtctcg atcaccgcgt cgacccgctg cggcagccgc
      301 gcgccgggct cgacggcctc cacggcgccc agctccagcg cccgcttgcg cttggcctcg
      361 tcccggctgg tggcgaagac ccgcagcccc gccgccttgc cgaggacgat cgcggcggtc
      421 gcgaccccgc cgccggcgcc ctgcacgagc acggagtcac cggggcgcac gcccgcgttg
      481 gtgaacagca tccggtacgc ggtcagccag gccgtgggca ggcaggccgc ctcctcgaag
      541 gacagctcct tcggcttggg caggatgttc caggtcggca cggagacctg ctcggcgaag
      601 gtgccctggt agcgctcggt caggatggag cggggctccc ggggtcccac gccgtgaccg
      661 gtctggccga tcaccgagtg gaggacgacc tcgttgccgt cctcgtcgat ccccgctgcg
      721 tcgcagccga ggatcatcgg cagcttgtcc tccgcgaggc cgacgccgcg cagggaccag
      781 aggtcgtggt ggttgaggga ggcggccttg accgtgacgg tgctccagcc cggacgggac
      841 tcgggagcgg gtcgctctcc cgactccagc cccgtgagcg gctggtcgcg gtcgattcgg
      901 gcggcgtaga cagcgaacat gaccttgacg ataggttccg cgccccgcct aaggaaccgt
      961 gcccccctgt gacacacgcc ctcttgcgcc ggaccggggc cctcacgaaa gaaccccgga
     1021 catgcgtgag ccccgcccac ggcgcggacg gggccctcac atctgtgcgc tcagcgccgc
     1081 gcgacgccct ccgcccgggc ggccgcggcc acggcggccg tcaccgcggg ggcgacccgc
     1141 tcgtcgaacg gggacgggat gacgtagtcg gcggcgaggt cgtcaccgac gacggcggcc
     1201 agcgcctcgg ccgcggcgag cttcatgccc tcggtgatcc gcgaggcccg cacctggagc
     1261 gcgccggcga agatgccggg gaacgccagg acgttgttga tctggttcgg gaagtccgac
     1321 cggccggtgg ccacgacggc cgcgtacttg tgcgcgacct ccgggtgcac ctccgggttc
     1381 gggttggcca tggcgaagac gaacgcaccc tccgccatcg acgccacggc gggctcgggg
     1441 accgtgccgc cggagacgcc gatgaagacg tcggcgcctg ccagcgcgga ctccagcgtg
     1501 ccggagatcc cggccttgtt ggtgaacgac gccagttccg ccttgatcgg cgtgaggtcc
     1561 tcgcggtccc gcgagaccac gcccttgcgg tcggccaccg cgacgtcccc gatgccggcc
     1621 tcgaccagca tcttggcgat cgcgacaccc gccgcgcccg ctccggagat caccgcccgc
     1681 agctcgccca gcggacgtcc gctgagccgc gccgcgttcc gcagggccgc cagcgtcacg
     1741 accgccgtgc cgtgctggtc gtcgtggaag accgggatgt ccaggcgctc ctggagccgc
     1801 cgctcgatct cgaagcaccg cggcgccgag atgtcctcga ggttcacccc gccgaaggag
     1861 ggggcgagcc ggaccacggt ctcgacgatc tcgtcgacgt cggtgcagtt cagcgcgagc
     1921 gggaccgcgt ccacgccgcc gaactgcttg aagaggatgg ccttgccctc catcaccggg
     1981 agggaggcct cggggccgat gtcaccgagc cccagcacgg ccgtgccgtc ggtcacgacg
     2041 gcgacgaccg aggacttcca cgtgtagtcg tggaccagct ccggctgctc ggcgatcgcg
     2101 ctgcacacct tcgcgacgcc gggcgtgtac gccagggaca ggtcgtcctt gtcacggacc
     2161 ggcacggtgg cctgcacggc catcttgccg ccgcggtgca gcgcgaacgc cgggtcaaag
     2221 gactccaggg gctctgcccc gccgtcccgc tcggaagcgt cccggttctc gctgtcgctg
     2281 cgaggattga caatctccgc tgccacttgg ttttacccct taagtgttca ttgtttgagg
     2341 gttgccactc ctggtgaggg gtgggcggga ccgcgccagg cccggagggg ttgatgcgta
     2401 cgggccgaac acgacgggcg cgccgcacac gcgccctgag ccccggatga ggggtgtaaa
     2461 gaaccttctt accggacgga cgcggtcggc gacgagtcca taacgcgaag gtcacacgcc
     2521 gacgccatga agcatcgtcc gatatcagga caagacctgg acgaagtccc agcaagcccg
     2581 caagtacccc tccggctcgg cgggtcgccc gctcaacagg catatcggcg aagatcttgc
     2641 ggccggaatg aaggattccc ggagagtctg cggtcgcgtt gtacccaagt ggccgggttc
     2701 gagggcccgc cgttatccga ttttgacatc gcaagccccc tgaacggtcc aatccgaatg
     2761 gcaagatgcg gtaatcacac gaggtcgcgg cactcgaagg tgtgtgccct tgtcgacccc
     2821 gcggcgatac cgacaggcag tcgccggccc catcggcact ccacccatcc gccggaggaa
     2881 tccaccatga ccgcaagcac cacccgtcgt accaccgccg cgcgctcacg gattgcagcg
     2941 gtcggcgcga tcgcggtcgc aggcgcactg cttctcaccg gctgcggtga ccagaccgaa
     3001 ggcagcggag gctcggacac caagggatcg ggcaagacca actccgcccc gctgttcgac
     3061 aagctgccca aggacatcca ggacgccggc gtcctgaagg cgggcacgaa cgccgagtac
     3121 gccccgatgg agttccagga gggcggcaag atcgtcggcg tcgaccccga catcgccgcc
     3181 gcgctgggcg agaagctggg tgtcgaggtc gagttcacct ccggcaattt cgacggcctg
     3241 atcaccgcgc tgaactcggg ccgctacgac atcgcgatgt cgtccatcac ggacaacaag
     3301 cagcgccagg agggtctgga cgacaagggc aagaagctcg gtccgggcgt cgacttcgtc
     3361 gactacttcg tggccggcac cgccgtgtac gtccagaagg gcaaccccaa ggggatcaac
     3421 tccatcgagg acctctgcgg tcagccggcc gccgtgcagc gcggcaccac gtacgagaag
     3481 gcgctgcagg accagtccaa gaagtgcacg gacgccggca agaaggcgat caagatccag
     3541 ccgttcgaga acgacaccga ggcgcagacc cgtgtgaagt ccggcggcgc ggtggccggt
     3601 gtgaacgact acccggtcgc ggtcgatctg gtccgcaagg ccgacaacgg caacgccttc
     3661 gagatcgtcg gcgagcaggt ggacgccggt ccgttcggca tcgcggtcaa caaggacaac
     3721 aagcagctca cggaggccct ggaggccgcc gtcaacgcca tcatcgagga cggcacgtac
     3781 aagaagatcc tcgagaagtg gggcgccgag accggcgcca tcgacaaggc cgtgatcaac
     3841 ggcggcaagt gacggtcccg ggcacgactg aagggcagtc acagtgaccg acaaactcga
     3901 caaggggacg gacggcgccc gaccggcggc caccgtctcc aaggacgaag ggcccgcccc
     3961 cgtggcgccc gcggtgatca aggccatccc ggtccgtcac tacggccgct acgtgagcgc
     4021 cgtcgtcgtg ctggccctgg tgggcctgct gatcaacgcc ttcgccaccg ctgagaagat
     4081 ccagtggcag gccgtcggcg actacgtctt cgacggcacc gtgctggccg gcgccggccg
     4141 caccctgctg atcagcgtcc tggccatggt catgggcgtg gtcctcggcg tggtcctcgc
     4201 cgtgatgcgc atgtcgaaga acccggtgac cagctgggtc gcctgggcgt acatctggtt
     4261 cttccgcggc accccggtct acgtgcagct gctgctgtgg ttcaacctgg cgctgatctt
     4321 cccggtgctg aacctcggtc cgctgtacaa ggacgagatg gtcgacgtca tgacgccgtt
     4381 catggcggcc ctgctgggtc tcggcctgaa cgaggcggcg tacatggcgg agatctgccg
     4441 tgcaggcctg cagtccgtcg acgacggcca gaccgaggcg gcgcacgcgc tcggaatgag
     4501 ccacggcaag acgctgcggc gcatcgtgat tccacaggcg atgcgggtga tcgtgccgcc
     4561 gaccggcaac gagttcctca acatgctgaa gacctcgtcg ctggtgtacg ccgtgaccta
     4621 caacgaactg ctgcgtgcca cctcaacgat cggctccacg tcgtacgccg tgatggagat
     4681 gctgttcgtg gcgtgcgtct ggtatctggt catcaccagt gtgttcagcg tcggccagta
     4741 ctacctggag cgccgtttcg cgcgcggctc gtcccggaac ctgcccgcga ccccgtggca
     4801 gaagatcaag gccaacatga tggccttcag ccgcgagagg agcagcacgg tatgacggcc
     4861 atggtgaagg ccgagggcgt ccacaagtcc ttcggcggtg tgcaggtcct caagggcatc
     4921 gacctggagg tcgagcaggg cgaggtgttc tgcctcatcg gcccctccgg ctcgggcaag
     4981 tcgaccttcc tgcggtgcat caaccacctg gagaagatca acgccggccg gctctacgtc
     5041 gacggcgagc tggtgggcta ccgccagaag ggcgacaagc tctacgagct gaaggacagc
     5101 gaggtcgccc agcagcgccg ggacatcggc atggtcttcc agcgcttcaa cctgttcccg
     5161 cacatgacgg ccgtcgagaa cgtcatggag gcgccggtcc aggtcaaggg cctcaaccgg
     5221 tccgcggccc ggcagcgggc gctcgagctg ctggaccggg tgggcctcgg cgacaaggcc
     5281 gggaactacc cctcccagct ctccggcggc cagcagcagc gggtggcgat cgcccgggcg
     5341 ctcgccatgg acccgaagct gatgctgttc gacgagccga cctcggcgct cgacccggag
     5401 ctggtcggtg acgtcctcga cgtcatgcgc gacctggccg agtcgggcat gacgatgatc
     5461 gtcgtcaccc acgagatggg cttcgcccgc gaggtgggcg acagcctggt gttcatggac
     5521 ggcggtgtgg tggtcgagtc cggccacccg cgcgaggtgc tgaccgaccc gcagcacgag
     5581 cgcaccaagt cgttcctgtc caaggtcctc tgacctcggc gcccgctcgg ccaaggggcg
     5641 gtacggattc ctccgtaccg ccccttccgc gtgttccggg cccgctactt cagcgccagc
     5701 agcagcgtgt ccgacggcga gcaccacacc gggcgggcct ccgcgaagcc cgcctcgcgc
     5761 aggacgcgcg cgtgccacgc aggggacggc atgtcgccgt cggcgtgctc gccgtagatc
     5821 tcgaagcggc gggcggtggg gccggcgagg acggggtcct tcgcggcgag ctgccaccat
     5881 tccgaccagt cgagggcgcc ccgctccttg gcccggtcca tgtgggcgtg gcgctgggcc
     5941 cgctcggcgg cgttgatccg gggggtggtc tcgtcgatca tgtggtcggc gttcatgaag
     6001 acgccgccct cgcggaccag gcccgcgagg tgtccgtaga ggtccgcgag gggttcccgg
     6061 tgcagccagt gcagggccgt cgcggtgagc acggcgtcgt aggagtcgtg cgggagctgt
     6121 gtggcccagc cggggtcctt gaggtcggcg gtgacgaagg tgacccgctc gtcgcccgcg
     6181 aaggtgccct cggcgatggc gagcagcgcc gggtcgaggt cgacgccggt gctggtggct
     6241 tcggggaagc ggtcgagcag ccgggcggtg atgctgccgg tgccgcaggc caggtcgagg
     6301 acgcgcgggg cggtgccgac gagggcctcc accatgtcga gcatgacccg gaagcgttcc
     6361 tcccggtcgg gcatgtacca ctcctgctgt cggtcccagc tctcctgcca ggcctgccag
     6421 tcggcgccgg ccgtggtggt gtgcgagtcc gtcatggccc ctccctcgcg gtgcactccg
     6481 taataccctg gacgcacgat cgtctgttac ccgaccgcac gcacgaccat agagcccctg
     6541 cgtaaggact acaagtggaa ctggcctatt actcggacta cgccgtacgt ctcgtgaaca
     6601 ccgaggagcc ggtccggggc accgacgtgc tcacctcggt cgaggccgtg cgggacctgt
     6661 tcggcggcaa ccggtcggcc gcccggcggg ccaccgaggc ggacgtgacg cggttccgct
     6721 cggtccgggc caggctccgg tcggtcttcg cggcggccga cgacggcgac gagaccctcg
     6781 ccgtggacct gctgaactcc ctgctgctgg agttcccggt gagcccgcag atctccggcc
     6841 acgacttccg cgacgacgac ggccgtccgc tgtggcacat gcacctggcc gaccacccgt
     6901 ccaacgcgac cgccgggtac gccgcgatcg ccgcgatggg cctggccttc cacctcaccg
     6961 agtacggcgt cgaccgcctc ggtctgtgcg aggcggcgcc ctgccgcaac gcctacctgg
     7021 acacctcgac caaccgctcc cggcgttact gctcggaccg ctgcgccacc cgtgcgaacg
     7081 tggccgccta ccgggcccgc aaacgcctgg aggcggaccg gtcggagagc acgggacggg
     7141 ccgacgtcag cagccagacc agcagcccaa gcggcgaccg ccgggccgtg gagcgcggcc
     7201 ggtagcggaa acggacccgg cccagcacca gctcgtcggg gacgacgccg tagtcggtgc
     7261 tgtcgccgcc cgcgtaggcg ttgtccccga gcacccacca gccgccgtcg cgccgctcgg
     7321 ccgcccgctt cacgaccagc aggtcctgct ggaacggatg gcgcagcacg atcacgtcgc
     7381 cgcgtctcac ccgcgccccg tagtggacca ggagccggtc cccgtggcgc agcgtgggca
     7441 ccatcgacgg cccggtcacc tcggccaccc cgaagggcag cggcgccctc acccgctcgg
     7501 cgtcctgcga cagctccggc atctcccggc acctccccgg ttcttctccc accagtctca
     7561 gtctgacccc ggacttttgt cctaagccca cgggggcact cgcgaaaacc ggtccgtcac
     7621 ggagtaatgt cccctgtgag aagacgatca cgaggaagga aacgcttcat gctttcccgc
     7681 ctgtttgccc ccacggtcaa ggtcagcgcg cactgcgacc tgccctgcgg tgtgtacgac
     7741 ccggcccagg cccgcatcga ggcggagtcg gtcaaggctg tccaggagaa gatggccggc
     7801 aacgacgacc cgcacttcca ggcccgtgcc acggtcatca aggagcagcg cgccgagctg
     7861 gcgaagcacc acgtctccgt gctgtggagc gactacttca agccgccgca cttcgagaag
     7921 tacccggagc tgcaccagct ggtcaacgac accctgaagg ccctctcggc cgccaagggg
     7981 tcgaccgacc cggccaccgg ccagaaggcg ctggactaca tcgcccagat cgacaagatc
     8041 ttctgggaga ccaagaaggc ctgacccggc ctcgccgctc ccagcggccg gcgatcggtg
     8101 caccatcgca ggtcctgggg cttttcccga agggggcccg tcgcttcacg cggcggggcc
     8161 ccttcggtgt ttcccggcgc cgtccgcggg acccgtggga tgctgggcgc atggagctgg
     8221 aagatctggt ccggctgcgg cgggccaggg accggatgga ccgggagtac gccgagccgc
     8281 tcgacgtcgc ggagctggcg cggacggcgc tgatgtcgcc gggccacttc cagcgcagct
     8341 tccgggccgc gtacgggcag acgccgtacg cgtatctgat gacgcggcgc atcgagcgcg
     8401 ccaaggcgct gctgcgcaag ggcgacctct cggtgaccga ggtgtgcctg gcggtcggct
     8461 gcacctcgct cgggtcgttc agctcgcgct tcaccgagct ggtcggggag acgccgagcg
     8521 cctatcgcgc ccgctcgcac gaggagagcg cggtcatccc gccgtgcgtc gtgcggacgt
     8581 acacccggcc ggtccgggtc cggcggcggg tcgacccgag cgggaactcc tagaagaaac
     8641 gggacacgga tggacagggc gacggacgta cggctcgccc agtgcttcgt cgcggtcgac
     8701 gaccacgaca aggcgctggc cttctactgc gacgtgctgg gcttcgaggt acgcaacgac
     8761 gtggggttcg aggggatgcg ctgggtgacc gtcgcctccc ccgagcagga cgtggagatc
     8821 gtcctggagc cgccggccgc gagcccggac atctcccccg ccgacaagca ggcgatggcc
     8881 gagctgctcg ccaagggcgt gctccgcggg gtcaacttca ccaccaccga ctgcgacgcc
     8941 ctcttcgagc gggtgcgggc cgcgggcgtc gacgtcctcc aggagccggt ggaccagccg
     9001 tacgggatgc gggactgcgc gttccgcgac ccggcgggga acatggtgcg cttcctggag
     9061 cgccccgcgg actgagagcc tgccgggcgc cggcccgttc agcgctgccc gcggtacgtc
     9121 cgcacgtgcc gaacgtcctg tacgacgagg gttcacttcg ccaggtgggg ggcgtccggt
     9181 caggcctggg cgccggccgc gcggggttcg cgccacatcg ggtacatgag cgggccgccg
     9241 ggcaggcgca ggggctcgcc ggtgagctcg aagccgaggc gacggtacag ccggacgctg
     9301 cgctcgctgc tcgcctccag gtacgcggcg cggccctcgc ggtcgcagcg gtcgaggacg
     9361 gagccgatca gcgcggtgcc gagcccttcg ccctgccgac cgggggccac gccgatcatc
     9421 cacaagtact cgtgggcgcg gccctggggg tgtatgcccg cggtgagccg gccgatcatc
     9481 tccacccgct cgttgtccgg gtcgacggcg tggcgcagtg cggcgaactc gtcgtcgccc
     9541 ccgtccgccc cgccgtgacc ggggtccccc gccgggacgg acatccacag ggcgcacgcc
     9601 gagccgtcct cgacgaggtc gacgcggccg tcggcgaggg tggcatcggt gaaggcggcc
     9661 atgagccggt ggtgcgtcac acgccggtac tccgctccgg ggaacaccca gctgctgacc
     9721 ggatcgtcct ggaacgcctc gtccagcagc cggaccacca gctcccggtc gtccccgccg
     9781 gccgtccgga tcgccacgcc catgtccgcc ccttcgtctc aacggtcgcc gcccgtacgg
     9841 gggttgagac tagccggacc ggcgggggaa cagggggcgg gccccgcaca ccgtggggaa
     9901 gtgcgggacc cgccgctccg ggaccacgga agccgtacgg gtcagggtcc gcacggcggc
     9961 acgtggtccc ggggtcgggg ggacggcctg cgccgtccgt tcaggtggtg cgccgggtga
    10021 cgaactcggc gagggccagc agccctcccg ccgcctccgg gtccggcacc gcacgggcca
    10081 cctcctgcat cgcgcgggcc atccggtccg ccgcctgggt ctgcgcccag tcacggccac
    10141 cggcccgctc cacgagccgg gtgagctcct cgacctcctc cttctggtgc ggggcggcgt
    10201 acgcggcggc gagctccgcc gcctccggag ttccggaggt gagcgcggcg acgaccggca
    10261 gcgacttctt gcgggcggcg aggtccgcac cggccggctt gccggtgcgg cgcgggtcgc
    10321 cccacgtgcc gatcacgtcg tcgatcagct ggaacgccag cccggcctcc cggccgaagg
    10381 cgtccatcgc cgccacctcc tcgtcccccg cgtccgcgta cagcgcgccg agggcgcagg
    10441 cgcagccgag cagggccccg gtcttggcct ccgccatggc gagggtctcc tccagggtga
    10501 cctcgtcggg tgcgcggcgc tccatggccg tgtccgcgtg ctgcccggcg cacagctcga
    10561 ccacgcactg ggtgagccgg gcggccgcgg ccggggcggc cgggtggggg tcctcggcga
    10621 gcagccgcag ggcgagcgcc tggagggcgt cccccaggag gatcgcgtcg gcgtccccga
    10681 acaccgtcca caccgtgggg cggtggcggc gggtggtgtc ccggtccatc acgtcgtcgt
    10741 ggacgagcgt gaagttgtgg accagctcga ccgcggccgc cgcccgcaga gccgccgtgc
    10801 gtgcggcgga accgccgagg gcggaggccg ccgcgagcac cagggcgggc cggagcgcct
    10861 tccccgaacc accggcggcc ggggtgccgt ccgcgttctg ccagccgaag tggtagagcg
    10921 cgagacgacg cagcggcgcg ggcagcgacc cgagggccgt gcgcagcacc gggtcgacgg
    10981 cggcccgggt ccgctccagc agggcggccg cctcgtgccc gtccccggcg tgcggatccg
    11041 gcccgggcgt gctgtcgggc gcggtgcgtg ccgtgcgctg ctccgggcgg cccgtggtcg
    11101 gccgggccat ggactccgtc atcgacttcc ccctgggacc gactcggtga gggcacggag
    11161 ggacggcgct tccgcacccg tcgagcacgt tccccccaga tgtacccgcc cgggagggcg
    11221 gggacacggc gcgcgtcgcg cgagccggcg gacggtcacc gccaccggcc gatctcgacg
    11281 ttctccagga cgcccagcgc gtccgggacc agcaccgccg ccgagtaata ggccgtgacc
    11341 aggtacttga tgatggcctg ttcgttgatg cccatgaacc gcaccgacag gctcggctcg
    11401 atctcgtcgg ggatgccggc cgcgcggagg ccgatgacgc cctggtcctc ctcgccggtg
    11461 cgcagcgcga tgatggaggt ggtgcgggcc tcggtcaccg ggatcttgtt gcacgggtag
    11521 atgggcacgc cccgccaggt ggggatgcgg ttgccgccga cgtcgacggt ctccgggacg
    11581 agtccccgct tgttgagctc gcggccgaac gcggcgatgg cacgcgggtg ggcgagcagc
    11641 agccgggtgc cgcggcgcct gctgagcagt tcgtccatgt cgtcggggcc gggcaccccg
    11701 tcgtgcggct ggatccgctg gtcgtactcg cagttgtgga gcaggccgaa gtcgcggttg
    11761 ttgatcagct cgtgctcctg gcgctccttc agcgcctcga cggtcagccg gatctgctgc
    11821 tccgtctggt tcatcggctg gttgtacagg tctgccacgc gcgtgtggat gcgcagcacg
    11881 gtctgggcga cgctgagttc gtactcgcgg ggccgggcct cgtagtcgac gaacgtgtgc
    11941 gggatgtccg gctcgccgct gtggccggcc gcgaggtcga tctccttctc gccgtacttg
    12001 ttggtgggct gctgcgggat gtcggcccgg cggcgcaggt gctcgcgcag ggtctcggac
    12061 cgctcggcta cctggtcgac cgcgtcgcgg ggcagcacca ggaccgtgca cgcggtaagg
    12121 gtgcgggccg tgtactccca gatggcgtcg tcgtcctgga gggcctgctc gccgaagtac
    12181 gcgccgtcgg cgagcactcc gagggactcg tcctccccgt agggtccggt gccgacgcgc
    12241 tccacccggc cgtgcgccag caggtacacc tcgtcggcgg ggctgccgaa ggaggcgatg
    12301 acctggcccg cctcgatctc ccgctgccgg cagcgggagg ccagctcgct gagcacctcc
    12361 tcgtcctcgt agtcacgcag cacgggcagt tcgcccagtt cggcggggat gatctccacc
    12421 cggtcgcccg tcttcacgaa ggtcagccgg ccgtcgccca cggcgtaggt cagccgccgg
    12481 ttgacccggt acgtgccgcc ctgcacgtcg acccagggca gcatccgcag cagccagcgc
    12541 gagctgatct cctgcatctg cggcacggac ttggtcgtgg tggccaggtt ccgcgccgcc
    12601 gccgtaccga ggctctgctg ctgcctggtc tgttccgtgc ggacctcttc gcctaccgac
    12661 atagagaatt gccctcccca atagatccac gcccggccgt gccgggcgtc gtggtgcgtg
    12721 atcaagcgtt cctcacgcat cgtgtccgcg ccattacccg atcgagcggg gttggatctt
    12781 ggcgggtctg ggcagagtga ccggcctgcc gacggcgaca acggcggccg tcgggaagga
    12841 gattgtccgg atcggctcgc acagcagccg aacgagtact tgaaaggccg actttcggct
    12901 atagcccctg taccagacgg ccgcgcccag cggccgtcgt ccggtacgaa ggagggcggc
    12961 atggccccac ccatgtccgc gagtgcgttc ctgcgcgcgc tcaaggcgga gggtctgacg
    13021 gtcgtcgagg tcggcgactg gcgtgaccac aaccgcaacc acaagggccc ctgggggccg
    13081 gtgcacgggg tgatgatcca tcacaccgtg accaagggca gcaaggcgac ggtcgacatc
    13141 tgccgcaagg gctactcggg tctgccgggg ccgctgtgcc acggcgtgat caccaaggac
    13201 ggccgggtgc acctcgtcgg ctacggccgc gccaatcacg cggggctcgg cgacgacgac
    13261 gtgctgcggg cggtgatcgc cgagaagaag acgttcccgc cggacaacga ggccaacacc
    13321 gacggcaacc ggcacttcta cggcttcgag tgcgagaacc tcggcgacgg gaaggacccg
    13381 tggccggcgg cgcagctgga ggccgtcgag aaggccgcgg cggcggtctg ccgccaccac
    13441 ggctggaacg agcagtcggt gatcggccac ctggagtggc agccgggcaa ggtggacccg
    13501 cgcgggttca ccatggcgtc gatgcgcaag cggatccgtg accgtctgaa gtgaccggac
    13561 cgtgtgaccg cccggcgtga ccggcgccgc ggcgctcgtc gccggtgttc cgcccccgag
    13621 gcgcccccca cgcggaacac cggcccccgc gcctgccctc acctcgggcg acaatggccc
    13681 gtatgaccag ctccgacgcc ctcgccggcc tgcgcccgcg gcttccctcg cctctggagg
    13741 aggccgtcga cgcgcggttc gagcggcacg gggtgcggct gctgctgaag cgggacgacc
    13801 tcgtccaccc cgagctggtc ggcaacaagt ggcgcaagct cgccccgaac ctggccgcgg
    13861 ccggcgggcg gacggttctc accttcggcg gggcgtactc cggccatctg cgggccacgg
    13921 ccgccgcagg ccggctgctc gggctgcgca cggtgggcgt ggtgcgcggc gaggagctgg
    13981 cggaccggcc gctcaacccg tcgctggcgc gctgcgcggc cgacggcatg cggctgcgct
    14041 tcgtggcgcg ctcggtgtac cgccgcaaga ccgatccgga cacgctcgcg gccgtgctgc
    14101 gcgcggcgga cgcggaggac gcccacgtcg tgcccgaggg cggcagcaac gccgccgcgg
    14161 tgcgcgggtg cgtggagctc ggccgggagc tggcgggcgc ggcggacgtg gccgcggtgg
    14221 cgtgcggcac gggcggcaca ctcgcgggac tggcagccgg gctcgccggg agcgcgcgga
    14281 cgctcggcat accggtgctc aggggcggct tcctcgcggg agagatacgg acccttcaga
    14341 cggaggcgtt cggcgggccg cgcggggcgt ggagcctgga cgagcggttc caccacggcg
    14401 gctacgcgcg cgtgccggcg gacctggagg cgttcgccgc ggacttcgaa cagcgtcacg
    14461 gcgtccctgt ggaacgtatc tatgtcgcca agttgcttcg tgcccttgtc accctggccg
    14521 gggagggcgc cttcccgcgt gggagcacgg tcgccgcggt gatcaccggc cggccgttcc
    14581 cctgaagcac gcgcccgctc cgggaaggcc tagtccgcct cccggtaggc cgcggcctcc
    14641 tccaggtcca gccgacgcag cagcgtccgc agcatctcgt cgtcgatgta gcgcgcgtcg
    14701 cgcagcttca cgaacacctc gcgctcggcg ccgatcatct cccgggacag ccgccggtag
    14761 gtgtcgtcca ccgactcccc ggtgacgggg ttgacctgcc cgagccgctc ccagacggcg
    14821 ttgcggcgac gctccaggac gctgcgcagc cggtcggcca gcggcgcggg gagggcgttg
    14881 cgctcgtcgg cgagcagtgc gtcgaggcgc tcctctgcgg cccgggacgc ctgcgcctgc
    14941 gcgttggcct cggcgagggt ctcgccccgc gggtcgcgcc cgggcagcct cagcagccgg
    15001 atcagcgggg gcagggtgag gccctgcacg acgagggtgc cgatgacggt ggtgaaggtc
    15061 aggaagagca gcaggtaccg gtgcgggaag tcctcgccct ccgcggtgac cgggatcgag
    15121 aaggcgatgg cgagcgacac caccccgcgc atccccgccc acgagatcac gaacggcccc
    15181 ttccagccgg gcctccgctc acgcgccctg atccgcgcgg agaccagcca cgggagccag
    15241 accgccggat agacccacag gaaccgcacc gcgacgacca ccgcgaagac ggccacggcg
    15301 taccaggcgg aggcgatgcc ctcgtgctcg ccgagcccgc gcatgacgac gggcagctgg
    15361 agcccgatga gggcgaacac ggccgactcc aggacgaacg cgaccatgcc ccacaccgcg
    15421 ccctcctgga gccgggtggc gaagtcgacc tcccacgcgc ggtgcccgag gtacagcgcg
    15481 accaccacga cggcgatcac cccggaggcg tgcacctgct cggccacggc gtacgcgacg
    15541 aacgggatga gcagcgacag cgtgttctgc agcagcgtct cgcgcagatg ggtgcgcagc
    15601 cagtgcagcg gcgccatcag caccaggccg accgccacgc cgccgacggc cgccagcagg
    15661 aactccccca ctccccccgc ccagctcacg ccctcgccga cggacgcggc cacggcgacc
    15721 cggaacgcgg tgatggcggt ggcgtcgttg aacagcgact cgccctggag gatggtcgtg
    15781 atccgcgagg gcaggccgac cctgcgggcc accgccgtcg ccgcgacggc gtccgggggc
    15841 gccaccaccg cgccgaacac cagcgccgcg gtgagcggca ggtccggcac cagcaggtac
    15901 agcacccagc ccacggcgag cgtcgcgaac agcacgtacc cgaaggacag cagggccacc
    15961 ggccgcagct gcgcccgcag gtccaggtag gagctgtcca cggccgccgt gtagaggagg
    16021 ggcgggagga tcagcggcag cacgatgtgc gggtcgagct cgtactcggg cacgcccggg
    16081 atgtagctga ccaccaggcc caccgcgacc agcaccagcg gcggcggcac cggagtccgc
    16141 cgggcggcgg cggccaccgc ggcgctgccc gcgaccagga gcagcagggg catcacgtcc
    16201 atgtcgggcc caccctcgtt tttccgcgcg gccgtgcgca cgaccgtcgt aatctggcaa
    16261 tcatgaaaca gtgcacgcac gtcgaggcgt tgccgcaccc ggaaccggcc gcgctcgatg
    16321 agacgtgtcc ggagtgtctg cgggagggga cggacccggt gcagcttcgc ctctgcctca
    16381 cctgcggcca cgtcggctgc tgcgactcct cgccgaaccg gcacgcggcg cggcaccaca
    16441 gggaaaccgg ccatcccgtg atgcggacct tcgagccggg tgaggactgg cgctggtgct
    16501 tcgtcgacca cgtactggtg tgacgtggcg ggaccacggt gccggacggt tcgacggtcc
    16561 ggcgcctggg tacgtcaatg cggcgcgcgc tcttcccatt tggccgtcgc agacccctag
    16621 ccacggagcg tgttcgcagt tttactatga gtgacagcaa cgggtcgggg tcccggcgac
    16681 aggaccgccg ggagcgcgat agcgtcaccg ctgaaccacg tagcgcgttg cccgggggcg
    16741 acacaggccc tgaaacgctt gtaccacctt ggaggtgagg gtgtcccaga tcgctggcga
    16801 gcccgcgacc caggacttcg tggaagtccg gctgccggcc gcgggggcct acctgtcggt
    16861 gctgcgtacg gccacggccg gcctcgcggc ccgtttggac ttcaccctcg acgagatcga
    16921 ggacctgcgc atcgcggtcg acgaggcctg cgcgatcctg ctccagcagg ccgtgccggg
    16981 gtcggtgctc agttgcgtct tccggctcgt cgacgactcg ctggaggtca ccgtctcggc
    17041 gcccaccacg gacggccacg ccccctcgcg ggacaccttc gcctggaccg tgctgtccgc
    17101 gctcgcgggc aaggtctcct ccgccgtgga cgaggacaga accgtgtcga tcagcctcta
    17161 caaacagcgc ggcgcgggac ccgggccggc gtgaggagcg aggacgggcc ggtgcgggac
    17221 gaagaacgcg gcacacggga gctgccggcc gagcgcgtgc cggacggtat cgacggcatc
    17281 cccgagcagg cccggccgca tccggaggac gactccgcga ggggcgtcgg gccgggcggc
    17341 gggcaggccg gcggtgccgt gcgggacacg tccgcggccg ggccggccgc tcctggcggg
    17401 gaggcccccg ccctggccga gccggtggcg ggggacgagg cgagcgctcg gggaagggcg
    17461 acgggcggga cgatgagcga gcacgagcga gaggccgagg agcaggcggc gcctgcctcc
    17521 ggcgcacgga gcacaccggg tgtgccgggc acgcacgcgc accacgaccc gcaggaccgc
    17581 agcggggcgc gcgccctctt cctcgaactg cgcacgctgg aggacggcac ccccgagtac
    17641 gcggagctgc gcaaccggct cgtgcggatg catctgccgc tcgtcgagca cctggcgcgc
    17701 cgtttccgca accgcggcga gccgctcgac gacctcacgc aggtcgccac catcggactg
    17761 atcaagtccg tcgaccgctt cgacccggag cggggcgtgg agttctccac gtacgccacc
    17821 ccgacggtcg tcggtgagat caagcggcac ttccgcgaca agggctgggc ggtgcgggtg
    17881 ccccggcggc tccaggagct gcggctggcg ctcaccacgg ccacggcgga gctgtcccag
    17941 ctgcacggcc gctcccccac ggtgcacgag ctcgccgaga agctggcgat ctcggaggag
    18001 gaggtcctgg agggcctgga gtcggcgaac gcctactcca cgctgtccct ggacgtcccc
    18061 gacaccgacg acgagtcccc ggcggtcgcc gacaccctcg gcgcggagga cgaggcgctg
    18121 gagggcgtgg agtaccggga atcgctcaag ccgctgctgg aggacctccc gccgcgcgag
    18181 aagcggatcc tgctgctgcg cttcttcggc aacatgaccc agtcgcagat cgcgcaggag
    18241 gtcggcatct cgcagatgca cgtctcccgg ctgctggccc gcaccctggc ccagctgcgg
    18301 gagaagctgc tcgtcgagga gtaggcgccg gcgcggcgcg tcactgcgcg gcgtcgcccg
    18361 cgttccctgg tccgcggatg ccgagggccc gggtggtctc cgcgttgatc agcagcacca
    18421 gcgcggtcac ggcgacgacg gcgagcgcga tcccggcggg gatggccacg ccgtccgacg
    18481 tcagcatgtt gtaggcgacg ggcagcgcca tgatctgcgt gatgacggcg ggcccgcggc
    18541 tccagctccg ccgggcgaac aggccccgcg cggccagcag cggcagcagc gccagcacga
    18601 tcagcgtgac cccgccggtg acggactgct gccggtcgtc cggctcgccc gcgagaccga
    18661 gcaccagcag ccagacgccg ccgaccacca gcgcgagccc ctccagcgcg gcgaggaccg
    18721 cggcgtacgt cagacggcgc ggacgggcgc cggtgtcgtc ggggctggtg gcgggggtct
    18781 gctcgctgct cacccctgca gggtagccgc cgccggggag ccgtcccgtg gcgaggttca
    18841 cgcccgagcc gtccacgggg cggggcctcg gtctgggccg ggtaccgctc agtaggtacg
    18901 ctgcacgtca tgcgtgcact tctcgtggtc aatccggcgg caaccaccac cagtgcgcgc
    18961 acgcgcgacg tgctgatcca cgcgctcgcc agtgagatga aactcgacgc ggtgaccacg
    19021 gagtaccgcg gtcacgcccg ggacctgggc cggcaggcgg cggagagcgg cgaggtcgac
    19081 ctggtggtcg ccctgggcgg cgacggcacg gtgaacgagg tcgtcaacgg cctgctgcac
    19141 gcggggcccg acccggagca cctgcccggt ctcgccgtgg tccccggcgg ctccaccaac
    19201 gtcttcgccc gtgccctcgg tctgcccaac cagcccgtgg aggcgaccgg cgcgctgctg
    19261 gacgcgctgc gcgagggccg ggagcggacg gtgggcctgg ggctgacctc gggcacgccg
    19321 ggcaccgagg acgaggcggt gcccgcccgc tggttcacct tcaacgcggg gctgggcttc
    19381 gacgccggcg tggtcggccg ggtggagcag cagcgggagc gcggccggcg gtcgacgcac
    19441 gcgctgtaca tgcgccaggt ggtgcgtcag ctgctgggcg acccgcaccg ccgcaacggc
    19501 gtgatcacac tggacctcga gggcgaggag ccggtcgagg acctggtgct gtccatagtc
    19561 tcgaacacct cgccgtggac gttcctcggc aaccgtccga tctacgcctc gccccaggcg
    19621 tcgttcgaca cgggactcga tctcttcggt ctcacccgga tgtccacgcc cgcggttgcc
    19681 cggtatggca cgcagttgct cacttcgtcc ccggagcgcg gaccccgcgg caagcacgcc
    19741 gtggtgcggc acgatctgac acgcttcacc ttgcattcga aggtgccgct gccccttcag
    19801 atggacggtg accacctcgg gctgcgtacc agcgtgacgt tcacaggcgt tcgccgtgca
    19861 ctgcgtgtga ttgtgtgagc agaaagggcc aaagtccttt cagtcgaacg tttaggccag
    19921 gatccacccc atggaagtac ggctgtgacc tagtcgacac cgaagaatca aaaaaaactt
    19981 tccggaaggg gttgtatccg ccgccgaggt ttgcgagtct cttcttggcg atcgggacgg
    20041 cccgcaacac cggcctccac agatcaccgg aacccctctt caaactcaag gaccacgcca
    20101 ggcaccctgg cgttcggccc ttcccttgtt gggggattcg tgaaagcgtt cacattcaca
    20161 agcacctgca gtaataccaa ggagaggtag cagccatgga ctggcgtcac aacgccgttt
    20221 gccgcgagga agaccccgag ctcttcttcc ccatcggcaa caccggtccc gcgctgctgc
    20281 agatcgagga agccaaggcc gtctgccgcc gctgcccggt gatcgagcag tgcctgcagt
    20341 gggcgctcga gtccggtcag gactccggcg tctggggtgg tctcagcgag gacgagcgtc
    20401 gcgcgatgaa gcgccgcgct gcccgcaacc gggcgcgtca ggcctccgcc tgacgacccc
    20461 gccccagcaa acagcctgag cttggcggcg cgtgtgcgcc cgtccggatg attccgtgga
    20521 cggcgcgcac gcatctcccg ccccgagccg cagcgcgaag ttcccccgac gcccgtcccg
    20581 atcgggcagg ggaagcgagg aacgagcatc agccccggac catggtccgg ggtcttttgc
    20641 tgttccgggg cctgtcgccg cccccagggg tgtgcgggac ccggagcgcg ccgggccccg
    20701 gcggtcagga gtccgcctgc accgggatgt cgaggatcac ccgggtcccc cgctccggcg
    20761 ccgggaccat gtcgaaggtg ccgcccaact ccccctccac cagcgtccgt acgatctgca
    20821 ggcccaggtt gcccgcggtg tgcgggtcga agccctcggg caggcccacg ccgtcgtcct
    20881 gcacggtgac cagcaggcgc gcctcccgcg aggtgccgcc gcgcaccgcg gacacctcga
    20941 cggttccggt ctcgccctca cggaagccgt gctccagggc gttctggagc acctcggtca
    21001 gcaccatcga cagcggcgtg gccacctcgg cgtcgagtat cccgaagcgg cccgagcgcc
    21061 ggccggtgac cttgcccggg gagatctccg cgaccatggc gagcacccgg tcggcgatct
    21121 cg
//
