LOCUS       NZ_BMTZ01000001        31240 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces variabilis strain JCM 4422 sequence01, whole genome
            shotgun sequence.
ACCESSION   NZ_BMTZ01000001
VERSION     NZ_BMTZ01000001.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces variabilis
  ORGANISM  Streptomyces variabilis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces griseoincarnatus
            group.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 699561)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: BGI assembly pipeline
            Genome Coverage                   :: 156X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014649935.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:37:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,743
            CDSs (total)                      :: 6,668
            Genes (coding)                    :: 6,496
            CDSs (with protein)               :: 6,496
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 172
            CDSs (without protein)            :: 172
            Pseudo Genes (ambiguous residues) :: 0 of 172
            Pseudo Genes (frameshifted)       :: 61 of 172
            Pseudo Genes (incomplete)         :: 147 of 172
            Pseudo Genes (internal stop)      :: 11 of 172
            Pseudo Genes (multiple problems)  :: 42 of 172
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:23:51
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 348919
            Orig. end                         :: 380159
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMTZ01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..31240
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NI-siderophore"
                     /region_number="3"
                     /rules="IucA_IucC"
                     /tool="antismash"
     cand_cluster    1..31240
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..31240
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[14000:17240]"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      14001..17240
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     gene            complement(240..1172)
                     /locus_tag="IE148_RS01500"
                     /old_locus_tag="GCM10010287_03030"
     CDS             complement(240..1172)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006136884.1"
                     /locus_tag="IE148_RS01500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03030"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_189363486.1"
                     /transl_table=11
                     /translation="MPTARTASPQVTTLRLGDVEITRVIEFSDISPMTTDVFFPGTTPE
                     EWRRHAALLDPDHWDARTDLTRVATQSWVLRSEGRVVVIDTGAGNGKYRPLQPIWSYLD
                     TGYLANLAAAGVRPEDVDLVVNTHLHDDHVGWNTCLDGRDWVPTFPNATYLMPAIDVTY
                     WHPDNLHRTQFGRGNQNVYEDSVQPVIDAGLVTTWESSYVIDGNLRLEPAPGHTPGSAV
                     VHLESGGERAVFAGDLLHGAIQIHEPHLNSCFEEDEEGARASRARMFAYAADHRALVFP
                     AHLPGQGAFEIRREGSGFGLARWAPFSRT"
     gene            1340..2233
                     /locus_tag="IE148_RS01505"
                     /old_locus_tag="GCM10010287_03040"
     CDS             1340..2233
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019521882.1"
                     /locus_tag="IE148_RS01505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03040"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_189363487.1"
                     /transl_table=11
                     /translation="MDRTSPLGAFLKARRARLSPDDVGLPRYGDRRRVPGLRREEVALL
                     AGVSAGYYTRLEQGQQGNASPEVLDALARALHLSPAERDHLHDLSPTTGHRTRPATSGD
                     DEKVSADLRTLLTTMAVHVPALVVGRRNDVLAWNRTGHALLAAHLDFAAPESPGTRPNL
                     SRLVFLDAPTRALYRDWPAKARAVVGNLRILTARNPGDTHLAALIAELTALSQEFRSMW
                     DAHTVAPCGRDVHTLSHPAVGELTVTQQTFDVPKEPHQSLVTFTAEPGSPSAVALEALK
                     CRGRIVDTPVACAPTP"
     misc_feature    complement(2321..2335)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.1"
                     /tool="antismash"
     misc_feature    2322..2336
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.98"
                     /tool="antismash"
     gene            2378..3286
                     /locus_tag="IE148_RS01510"
                     /old_locus_tag="GCM10010287_03050"
     CDS             2378..3286
                     /EC_number="2.3.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020134701.1"
                     /locus_tag="IE148_RS01510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03050"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_189363488.1"
                     /transl_table=11
                     /translation="MTDLVIRTLSASDAHLFDALPDPLGAREAHRRTRFRPDWKRVVLR
                     DGEVVARGAWWGGPDDPEPVNINWFDVAEGEEKAGAELLRSAPRQVELEINLPGGWRDD
                     PVLRAAAEARFTAARAAGYELLVERFLYRWTPDRGLPDRPGRLNFRPEPDDTVFFDALR
                     RIHSVTLDAHALKAVEEGGLDQAAQEELDFFHWCPSPRDWWRTAHTPDGDLAGIHIPAH
                     NPSGPTIGFIGVVPEHRGHGYAYDLLVECTRHLVEQGAEHISAATDRGNIPMAACFAEA
                     GFPVVRERVNFHPATATTAEL"
     gene            complement(3402..3734)
                     /locus_tag="IE148_RS01515"
                     /old_locus_tag="GCM10010287_03060"
     CDS             complement(3402..3734)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004000468.1"
                     /locus_tag="IE148_RS01515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03060"
                     /product="barstar family protein"
                     /protein_id="WP_189363489.1"
                     /transl_table=11
                     /translation="MTDETDGTSEVEPTVPDSLVIDLTEVRDAEGLQRLLQRELQFPDF
                     YGRNWNAFWDAVTGLVDLPYELTFTGWDAFSASLPAEAGTLRELLDDYLSEYGQYHAVP
                     RRIRYQ"
     gene            complement(3750..4187)
                     /locus_tag="IE148_RS01520"
                     /old_locus_tag="GCM10010287_03070"
     CDS             complement(3750..4187)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE148_RS01520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010287_03070"
                     /product="ribonuclease domain-containing protein"
                     /protein_id="WP_220450253.1"
                     /transl_table=11
                     /translation="MGAVVILRTMKAGYKGADSLYNASRLTAVLSTAEKANPLIDSLRK
                     TGKLPSNYVTKSQAAQKGWEPGKALGNHVPGGQIGGDIFRDPASIGLPTESGRVWYEAD
                     VGLTNTMKRSKQPGTRLLYSDDGLLYVTTDHYKTVDYVGTY"
     gene            complement(4157..4891)
                     /locus_tag="IE148_RS01525"
                     /old_locus_tag="GCM10010287_03080"
     CDS             complement(4157..4891)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE148_RS01525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010287_03080"
                     /product="hypothetical protein"
                     /protein_id="WP_189363490.1"
                     /transl_table=11
                     /translation="MQECLDKPLTERPACLEDLVHQIAERGVTWFLVLHLIHEARDGQL
                     DAQYAYDATVKAYAALDDPSLLLTDEALRTKFLQSAAKAEKKGKAAAAFGREAVKVTKS
                     TAKLLRDTMYLIKELEVGKTYKDIMSALDTMNAGMAQMNSGLDQMNQGVAEVNAGLKHA
                     NAGIDRANRGMAQMNKGISEANKALAETDKAVKNMAKGFEQLNHITPGRIDFDFSNLDT
                     LPPVNLCPAWTAPWEQSSSCAR"
     gene            complement(4842..5087)
                     /locus_tag="IE148_RS01530"
                     /old_locus_tag="GCM10010287_03090"
     CDS             complement(4842..5087)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE148_RS01530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010287_03090"
                     /product="hypothetical protein"
                     /protein_id="WP_189363491.1"
                     /transl_table=11
                     /translation="MRQNKPVSRIVTAVLAMVLALTGTIAAAPAQPATAASSPLASCEN
                     LNLLKKIGCVRDALKKTAGVGAGMPGQTADRAPGLP"
     misc_feature    complement(5074..5087)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.32"
                     /tool="antismash"
     misc_feature    complement(5173..5187)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.35"
                     /tool="antismash"
     misc_feature    complement(5174..5187)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 17.88"
                     /tool="antismash"
     misc_feature    complement(5175..5188)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.09"
                     /tool="antismash"
     misc_feature    5202..5220
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.9"
                     /tool="antismash"
     gene            complement(5338..5715)
                     /locus_tag="IE148_RS01535"
                     /old_locus_tag="GCM10010287_03100"
     CDS             complement(5338..5715)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018101811.1"
                     /locus_tag="IE148_RS01535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03100"
                     /product="hypothetical protein"
                     /protein_id="WP_086704605.1"
                     /transl_table=11
                     /translation="MTETWVIDGSSLVPVSSATVVRGLRSRINSGHLETWMTSSSGRSL
                     AFVTNNERAMVMLFEEEGGPGEHAVDPGAEGSSDGYVLSNGQHDAYPDADTVPVHEAFR
                     LVQRIVRTGSWPQDTRRVVDR"
     gene            complement(5739..6704)
                     /locus_tag="IE148_RS01540"
                     /old_locus_tag="GCM10010287_03110"
     CDS             complement(5739..6704)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019330743.1"
                     /locus_tag="IE148_RS01540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03110"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_189363492.1"
                     /transl_table=11
                     /translation="MRTRYDDLWGIGELAARAGVTVKTVRFYSDGGLLPEASRSAGGHR
                     RYGSDALDRLRLIRSLRTLGLSVPEVRRVLDEEDATDGLGQALEGAVAERLRELGTEIR
                     SLRWREAALRLVQESTPGERADRLQLIGGLSVPPSTAPLVRFWRGWLPPRMPRRSVDAF
                     LDVAVPQPPDDPAPAQVLAFARLNALTLGPCPGAAQPQPEAHRAVGAQGAAVLYAGLAE
                     AYELAGVQLRRGREPRPGEALDCFVDAYTGAYGVRDGEQFRRGLAGQLATDARIDRYWE
                     LVAEVVTEPGRRPEPTPGTAHDWLLAALAAQTGTPPTTAV"
     gene            6793..8334
                     /locus_tag="IE148_RS01545"
                     /old_locus_tag="GCM10010287_03120"
     CDS             6793..8334
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019761731.1"
                     /locus_tag="IE148_RS01545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03120"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_189363493.1"
                     /transl_table=11
                     /translation="MTIFVLVPGMFTGAHVWQETADRLTAAGAVAHPVRLTGLDAALRP
                     AGGDIDLETHIADVVEVIDSLGRTGRKLVLVGHDYGIHPALGAADRRAGRVDRIVYLDS
                     GMPGNGVPAVAAVPDRSLRDRTAATDGKALPPPATPEDWRRWGSTEGVPGPALDQLTAM
                     AAPQPMGTLLQPLRLTGAVDPVPATGILCTGNGASIEMVQMMVDRGDPTLRELADARVA
                     FFELPTGHWPMLSMPAELADVLLRAAAGEGHRLAPADASEPPAHLRPFPLEVPEAPRER
                     HGNVDLYLPPGAEAPRPAVLFVHGGPVPADARPTPRDWPTLRGYAHCAAAGGAVAAVVD
                     HRLHTLDDYERAAADVAAAMEQVRADPRVDADRAALWFFSGGGPIAAPWLDAPPPWLRC
                     LAATYAVLGPLPGWGLTDSRFDPARAVAHAGGLPVVLTRVGLETPAIAATVEGFLASAK
                     ECGADVEVVDVPRGHHAFETVDPTDESRDAVRRAIRAVLDRLGVPDTHQGFPPAG"
     gene            complement(8554..9762)
                     /locus_tag="IE148_RS01550"
                     /old_locus_tag="GCM10010287_03130"
     CDS             complement(8554..9762)
                     /EC_number="2.6.1.-"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (33-393). E-value:
                     8.8e-55. Score: 178.2. Matches aSDomain:
                     nrpspksdomains_IE148_RS01550_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007390030.1"
                     /locus_tag="IE148_RS01550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03130"
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="WP_189363494.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 8.5e-54, bitscore:
                     178.3, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 1.4e-06, bitscore:
                     22.7, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 3.9e-07,
                     bitscore: 24.8, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFRQSSKLSEVCYEIRGPVIEHANALEEAGHSVLRLNTGNPALF
                     GFEAPEEILQDMIRMLPQAHGYTDSRGILSARRAVAQRYQTLGLEVDVDDVFLGNGVSE
                     LVSMAVQALLEDGDEILIPAPDFPLWTAVTTLSGGKAVHYLCDERSDWYPDLDDMAAKI
                     TDRTKAVVIINPNNPTGAVYPKEVVEGILDLARRHGLMVLADEIYDQILYDDAVHHSAA
                     ALAPDLVVLTFCGLSKTYRVAGFRSGWLVVTGPKQHAKDYLEGLTMLASMRLCANAPAQ
                     YAIQAALGGRQSIRDLTAPGGRLREQRDTAWEKLNEIPGVSCVKPKGALYAFPRLDPKV
                     HKIHDDEKFVLDLLLREKIQVVQGTGFNWPSPDHFRILTLPHAEDLEAAIGRIGRFLSG
                     YRQ"
     aSDomain        complement(8584..9663)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE148_RS01550_Aminotran_1_2.1"
                     /evalue="8.80E-55"
                     /label="IE148_RS01550_Aminotran_1_2.1"
                     /locus_tag="IE148_RS01550"
                     /protein_end="393"
                     /protein_start="33"
                     /score="178.2"
                     /tool="antismash"
                     /translation="VLRLNTGNPALFGFEAPEEILQDMIRMLPQAHGYTDSRGILSARR
                     AVAQRYQTLGLEVDVDDVFLGNGVSELVSMAVQALLEDGDEILIPAPDFPLWTAVTTLS
                     GGKAVHYLCDERSDWYPDLDDMAAKITDRTKAVVIINPNNPTGAVYPKEVVEGILDLAR
                     RHGLMVLADEIYDQILYDDAVHHSAAALAPDLVVLTFCGLSKTYRVAGFRSGWLVVTGP
                     KQHAKDYLEGLTMLASMRLCANAPAQYAIQAALGGRQSIRDLTAPGGRLREQRDTAWEK
                     LNEIPGVSCVKPKGALYAFPRLDPKVHKIHDDEKFVLDLLLREKIQVVQGTGFNWPSPD
                     HFRILTLPHAEDLEAAIGRI"
     gene            9844..10470
                     /locus_tag="IE148_RS01555"
                     /old_locus_tag="GCM10010287_03140"
     CDS             9844..10470
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006136895.1"
                     /locus_tag="IE148_RS01555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03140"
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="WP_189363495.1"
                     /transl_table=11
                     /translation="MPPRRSYDQYCSAARALDVVGDRWTLLIVRELLAGPRRYTDLHAD
                     LPGVSTDVLASRLKDMERDGLTTRRRLPPPGAVYVYELTARGRELLPVLQALGTWGRPE
                     LGARRPTDAVRAHWFALPLLRELEGDGLVEVRLDEGCFHVHAGAADSPVYGDGPAPRDP
                     DAVLTLDTPACIALSRGDLSLPEAIRDGRVEITGDSPLAKQLREA"
     gene            10639..11181
                     /locus_tag="IE148_RS01560"
                     /old_locus_tag="GCM10010287_03150"
     CDS             10639..11181
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE148_RS01560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010287_03150"
                     /product="hypothetical protein"
                     /protein_id="WP_189363496.1"
                     /transl_table=11
                     /translation="MGWSFKVHGGIALAMSATALLLALLSWVPGMTLSLTDVDWLAVVV
                     LMLPVVLAAGVRVLLTGSDKKTLWRAFWCLPGRLQATLGVLFISGFALFFMGMSNDTRQ
                     QTEMIKDGRYYVFDMTTSKRALVEVPRSQYEKVAREDQRPMFAGFTWLCAVSAFGVFTA
                     GELRRADARSGSVDAAT"
     gene            11293..11817
                     /locus_tag="IE148_RS01565"
                     /old_locus_tag="GCM10010287_03160"
     CDS             11293..11817
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019324402.1"
                     /locus_tag="IE148_RS01565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03160"
                     /product="DUF3291 domain-containing protein"
                     /protein_id="WP_086704601.1"
                     /transl_table=11
                     /translation="MPRLALYTFGVLKSPLSDPGPITREFYDIGEAVYRRISAHPGYLG
                     RAEPEGGEHGVLFGADWGAWGEFAVPAWYAKGRTPDTTALAATLSLWTDLRSARDAVHT
                     GLHREALTRRHDWFERSRHPTHVLWWVPEDATPTWREGVGKLERLHHHGPAPQRFTFPQ
                     PFTPEGAPTCG"
     gene            complement(11881..12681)
                     /locus_tag="IE148_RS01570"
                     /old_locus_tag="GCM10010287_03170"
     CDS             complement(11881..12681)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016823987.1"
                     /locus_tag="IE148_RS01570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03170"
                     /product="hypothetical protein"
                     /protein_id="WP_189363497.1"
                     /transl_table=11
                     /translation="MRAVRVLSAALLTLGLAAAPAAADSSPSPEASGDGGGPTRAGTSF
                     RTATEVEQGQTATARASTGDYLYWSFPADAGQRPTVRATVKLPESHAAQTWQVDVYDGL
                     RRRQACQYGAQTRTAGAGAASVELACVLRTVRAWSEPWANDPLPGTYYVRLTALKLSAD
                     DLGKPVDAELRVKSKDMGGATAVDGSLSEPLVPGVASRPQEESDDSPSAVLADLEPEDG
                     WTSGWWSDRWIWTAIGGALAALAGVCGYRLTRGPGRPRHVPPGA"
     gene            complement(12681..13955)
                     /locus_tag="IE148_RS01575"
                     /old_locus_tag="GCM10010287_03180"
     CDS             complement(12681..13955)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385720.1"
                     /locus_tag="IE148_RS01575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03180"
                     /product="VWA domain-containing protein"
                     /protein_id="WP_086704602.1"
                     /transl_table=11
                     /translation="MIRRTRPVVGAIALLAALTAGIAFPAGAAAGEPTGESAPKVDLVL
                     DVSGSMRAKDIDGQSRMAAAKQAFNEVLDATPEEVQLGIRTLGADYPGDDRKEGCKDTA
                     QLYPVGPLDRTEAKTAVATLVPTGWTPIGPALLQAADDLDGGDGSKRIVLISDGEDTCA
                     PLDPCEVAREIAAKGIGLTIDTLGLVPNAKLSRQLSCIAEATGGTYTSIEHQDELTDRV
                     NELVDRAAEPVVTPVAVEGADACERAPELRSGLYTDRQEFGQQRWYRVELLAGQELRAS
                     VSIAADRAVRPDHGVLMRAVTVHGREIVRGEATGNGRTDVVSTGLRHPKPELDDDDSGK
                     PAAETVCLGVTTSFSADAGVKTTPGLPLELTVDVVDGPDDASDVASFGLGRGWWLLGAL
                     VVTGFLAGLVWGWLSRWRVAVWRTN"
     gene            complement(14001..15587)
                     /locus_tag="IE148_RS01580"
                     /old_locus_tag="GCM10010287_03190"
     CDS             complement(14001..15587)
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006136900.1"
                     /locus_tag="IE148_RS01580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03190"
                     /product="IucA/IucC family protein"
                     /protein_id="WP_189363498.1"
                     /sec_met_domain="IucA_IucC (E-value: 8.7e-38, bitscore:
                     125.4, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRPSTAEAEIAEELAVVRPALLPAYTRALPGARAAVLTRLWRGL
                     THDPLPWITGREDTRSGVVLRLADGRRLEGPVPDPYATNAGVTAVRLDGTEYDDPARLM
                     ADLAVPHSGSFAAELGHSTASLALSRAGQRDFGGPGDAAPVRDWEWEQRVVDGHPFHPN
                     CRSRPGFSVAEQLAYGPEHRPVVELELIPVPARECLVSGAWPDRLRDGDRVLVPVHPWQ
                     AAHVLKRAGEPGASGRGEGTASASRQGAASVRGEGALAAHPLMALRTLALPDGPHVKTA
                     VSARLTSSVRDISLGSVAASAALSDFGQAVAERTDGLLRITRTPAAVAAGSPDLTALLR
                     ESPEKYAGPGERVVPVAALAATDLPRSPARLARLARLALTVGLRLLDLGVALEAHGQNL
                     LVVLSPDGEPVRLVYRDLADLRVSPARLARHGIPVPDVPDRMVTDDALALRRKLFGSLV
                     AGALAGTAGSGSALRAALETAVPDLPRTDDLSALLGGPLPAKALTLMRLSPGTAGDQWA
                     ELPNPLRSGSG"
     gene            15696..17240
                     /locus_tag="IE148_RS01585"
                     /old_locus_tag="GCM10010287_03200"
     CDS             15696..17240
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006136901.1"
                     /locus_tag="IE148_RS01585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03200"
                     /product="IucA/IucC family siderophore biosynthesis
                     protein"
                     /protein_id="WP_189363662.1"
                     /sec_met_domain="IucA_IucC (E-value: 1.7e-42, bitscore:
                     140.8, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPPADDDAASRADLAGRADAHAAVPLLNCLLREVAEPLPGPARP
                     DGPRTYRLPHSRRLLRVRGARRPTAPEVHTAGSWRRLTHAELVKLVAEELRRHTGRSNY
                     ELPAEMLDSRDAVAALLAARDRADPPDGLYPRSEQSLLTGHTHHPAPKARGGGPAAGWL
                     PYAPEAYARFPLALLGVREDTLVDEGDTAALDRLGAAPPGYRLLPAHPWQLDLAADDLA
                     PAFADGRLLRLGETPWPVWPTAAVRTVHAPAEDLFLKFSLDVRITNDIRRLWRHDLARL
                     RVTDTAVRDAFADGPAGGAWLSDRGHRTADFAFEQLAVVVRDGFRGRLVPGATPCLAAA
                     LVEGFAGDPLAATDRPAAWWEAYLARVVPPALAAFHRHGVVLEAHLQNTLIAVDADGMP
                     VQALYRDAEGVKLLASPHRPGGPPTVTREAGWERLVYCLVVNHLMEIAAALADHHPGLD
                     PWPAVRRELARHDLPEIPALLTAPTLPAKTNLLLRWTAADGADARYRPLPNPLSGH"
     gene            17365..18318
                     /locus_tag="IE148_RS01590"
                     /old_locus_tag="GCM10010287_03210"
     CDS             17365..18318
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006136902.1"
                     /locus_tag="IE148_RS01590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03210"
                     /product="TerC/Alx family metal homeostasis membrane
                     protein"
                     /protein_id="WP_102638105.1"
                     /transl_table=11
                     /translation="MHDVPFWLWIVFVVIVVVSLAIDLFAHRSAHVIDFREAAAWSAGW
                     IGLAIVFGGVVFLVVGTDAGVEYTTAWLLEKSLSVDNLFVFALIFSYFQVPRAYQHRVL
                     FLGVLGALVFRGLFLAAGVAVVSRFTAVLYVFAAILFWSTYKILKGEEESFDPGKSIAV
                     RLLRKVVPVRDEYAGPHFFVKEAGKRVATPLLAVVAAIEAADLVFAVDSVPAVLAVSSD
                     VFIVYTSNAFAILGLRALYFMLAGLLDRFHYLSVGLALILGFIGVKLVLQATHETVSTA
                     VPEIPSLVSLAVIVVVLAVSITVSVLRPPAEQDENT"
     gene            18339..18575
                     /locus_tag="IE148_RS01595"
                     /old_locus_tag="GCM10010287_03220"
     CDS             18339..18575
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006136903.1"
                     /locus_tag="IE148_RS01595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03220"
                     /product="hypothetical protein"
                     /protein_id="WP_086705258.1"
                     /transl_table=11
                     /translation="MSSDRRRDGSRSTELLCGSCGQPVDTVVTRHKTMGINVPRWRAGP
                     CHNPDCPDYVPEMVPADTLRRAEEREKETGPPA"
     gene            18651..19565
                     /locus_tag="IE148_RS01600"
                     /old_locus_tag="GCM10010287_03230"
     CDS             18651..19565
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016823965.1"
                     /locus_tag="IE148_RS01600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03230"
                     /product="HipA family kinase"
                     /protein_id="WP_189363499.1"
                     /transl_table=11
                     /translation="MLKQVTATRYVEPLHSGGSVPGVVEADDLGTYVVKFTGSAQGRKA
                     LVAEVIVGELARALGLRFPELVLVHFDPAIADAEPHQEVRDLHAASAGVNLGMDHLPGA
                     RDFTPEAAETFAVDPLEAGRIVWLDALTANVDRTVHSSNLLLWPTLGVAPPRLWLIDHG
                     AALVFHHRWDAGDPAKAYDFRHHALGRYGPDVRAADAELAPRVTEELLRSIVHQVPDPW
                     LDGEPGFASPEAVRAAYVEHLHARARASGAWLPLDFPTAEEIAAENALRAARTQQGRPA
                     WLKQVPDLHGRPAVEQDGTVHLR"
     gene            19562..19840
                     /locus_tag="IE148_RS01605"
                     /old_locus_tag="GCM10010287_03240"
     CDS             19562..19840
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019521865.1"
                     /locus_tag="IE148_RS01605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03240"
                     /product="SelT/SelW/SelH family protein"
                     /protein_id="WP_086705256.1"
                     /transl_table=11
                     /translation="MTADARRVEIEYCTRCRWLPRAAWLAQELLTTFEQELTELALRPG
                     TGGVFVVRVGGEVVWDRREQGFPEPTAVKQAVRDRVAPGKPLGHSER"
     gene            complement(19860..21485)
                     /gene="aceB"
                     /locus_tag="IE148_RS01610"
                     /old_locus_tag="GCM10010287_03250"
     CDS             complement(19860..21485)
                     /EC_number="2.3.3.9"
                     /GO_function="GO:0004474 - malate synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006097 - glyoxylate cycle [Evidence IEA]"
                     /codon_start=1
                     /gene="aceB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020133434.1"
                     /locus_tag="IE148_RS01610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03250"
                     /product="malate synthase A"
                     /protein_id="WP_086705255.1"
                     /transl_table=11
                     /translation="MSAPAPSPLAIVDAEPLPRQEEVLSETALAFLAELHRRFTPRRDE
                     LLARRAERRAEIARTSTLDFLPETAAIRADDSWKVAPAPPALEDRRVEITGPTDRKMTV
                     NALNSGAKVWLADFEDASAPTWENVVTGQLNLIDAYTRGIDFTDERTGKTYALRPDEEL
                     ATVVMRPRGWHLDERHLTDAGGAPVPGALVDFGLYFFHNAKRLLDLGKGPYFYLPKTES
                     HLEARLWNDVFVFAQDYLGVPRGTVRATVLIETITAAYEMEEILYELRDHASGLNAGRW
                     DYLFSIVKNFRDAGPGFVLPDRNAVTMTAPFMRAYTELLVRTCHRRGAHAIGGMAAFIP
                     SRRDEEVNKVAFEKVKADKDREANDGFDGSWVAHPDLVPIAMESFDRVLGDRPNQKDRL
                     REDVDVKAEDLIAIGSLDARPTYAGLVNAVQVGIRYIEAWLRGLGAVAIFNLMEDAATA
                     EISRSQIWQWINAGVVLDNGERVTAELARKVAAEELADIRAEIGDEAFTAGNWQQAHDL
                     LLKVALDEDYADFLTLPAYQQLKG"
     gene            complement(21639..22238)
                     /locus_tag="IE148_RS01615"
                     /old_locus_tag="GCM10010287_03260"
     CDS             complement(21639..22238)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006136906.1"
                     /locus_tag="IE148_RS01615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03260"
                     /product="NTP transferase domain-containing protein"
                     /protein_id="WP_189363500.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 5.7e-37, bitscore:
                     122.7, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDDENRVAGLLLAAGGGRRLGGRPKALLPHRGRLLVEHAAEVLR
                     AGGCASVHVVLGARADEVRARAELPDCALVDNPDWEHGMGTSLRAGLGALAGAGARAAL
                     VLLVDQPGIGPEAVARVRHAYRSPRSLASAAYDGVRGHPVLFGAGHWAGIAATATGDRG
                     ARAYLREHADAVELVECGDVAEAYDIDTEADLAHLE"
     misc_feature    22307..22320
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.99"
                     /tool="antismash"
     gene            22445..22759
                     /locus_tag="IE148_RS01620"
                     /old_locus_tag="GCM10010287_03270"
     CDS             22445..22759
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431816.1"
                     /locus_tag="IE148_RS01620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03270"
                     /product="DUF5955 family protein"
                     /protein_id="WP_086705253.1"
                     /transl_table=11
                     /translation="MLRGVDQRCVPGSQVDPRVAELRSAVARLRRQLAAHRVEFRDRGV
                     AEEALAMLAGLAAADHPDIPVLRRSLLLVAGAIGSVSALGEGLRQLREAVDLFGTSPRA
                     "
     misc_feature    22529..22531
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(22923..23729)
                     /locus_tag="IE148_RS01625"
                     /old_locus_tag="GCM10010287_03280"
     CDS             complement(22923..23729)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972681.1"
                     /locus_tag="IE148_RS01625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03280"
                     /product="IclR family transcriptional regulator"
                     /protein_id="WP_086705252.1"
                     /transl_table=11
                     /translation="MPTSSASTTDSARPAASGGVQSLERAFDLLERMADAGGEVGLSEL
                     SASSGLPLPTIHRLMRTLVACGYVRQQPNRRYALGPRLIRLGESASRLLGTWARPYLAR
                     LVEETGETANMALLDGDEIVYVAQVPSKHSMRMFTEVGRRVLPHSTGVGKALLAGFPPQ
                     EVRALLGRTGMPAATDRTITTPEGFLAALEEVRRQGYAIDDNEQEIGVRCLAVPVPDAP
                     TAAAVSISGPAGRVTESATERIVPVLQEIARELSEALANPGGGPAA"
     misc_feature    23815..23830
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.42"
                     /tool="antismash"
     gene            23966..25303
                     /gene="allB"
                     /locus_tag="IE148_RS01630"
                     /old_locus_tag="GCM10010287_03290"
     CDS             23966..25303
                     /EC_number="3.5.2.5"
                     /GO_function="GO:0004038 - allantoinase activity [Evidence
                     IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0050897 - cobalt ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0000256 - allantoin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="allB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006136912.1"
                     /locus_tag="IE148_RS01630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03290"
                     /product="allantoinase AllB"
                     /protein_id="WP_189363501.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 9.9e-24, bitscore:
                     79.4, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDVQLVLRSTRVVTPEGMRAASVAVAGGTVTAVLPHDAPVPDGA
                     RLEDLGDDVLLPGLVDTHVHVNDPGRTEWEGFWTATRAAAAGGITTLVDMPLNSLPPTT
                     TVDHLRVKRKTAADKAHIDVGFWGGALPDNVADLRPLHEAGVFGFKAFLSPSGVDEFPH
                     LDQEQLARALREIASFDGLLIVHAEDPGHLADAPQRGGPRYADFLASRPRRAEDTAIAQ
                     LLEQARRFDARVHVLHLSSADALPLIAEAKADGVRVTAETCPHYLTLTAEEVPDGASEF
                     KCCPPIREAANQDLLWQALADGTVDCVVTDHSPSTADLKTDDFATAWGGISGLQLSLPA
                     VWTEARRRGHALEDVVRWTATRTARLAGLGARKGAIAPGRDADFAVLAPDETFTVDPAA
                     LQHRNRVTAYAGRTLHGVVRSTWLRGERVLSDGEFTAPKGRLLTRP"
     gene            25335..26450
                     /gene="alc"
                     /locus_tag="IE148_RS01635"
                     /old_locus_tag="GCM10010287_03300"
     CDS             25335..26450
                     /EC_number="3.5.3.4"
                     /GO_function="GO:0004037 - allantoicase activity [Evidence
                     IEA]"
                     /GO_process="GO:0000256 - allantoin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="alc"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571646.1"
                     /locus_tag="IE148_RS01635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03300"
                     /product="allantoicase"
                     /protein_id="WP_189363502.1"
                     /transl_table=11
                     /translation="MTAIETFTGDASPYGGGDPYADYRTADFPFTHLADLADRRLGAGV
                     IAANDEFFAERENLLLPGRPVFDPERFGHKGKIMDGWETRRRRGVSADHPWPAEDDHDW
                     ALIRLGTPGVVRGVVVDTAHFRGNYPQAVSVEGTAVDGSPSPEELLSDEVKWTTLVPRT
                     RIGGHAANGFAVTAEQRFTHLRLNQHPDGGIARLRVYGEVVPDLAWLTALGTFDVVALE
                     NGGRVEDASDRFYSPAANTVRPGRSRKMDDGWETRRRRDHGHDWITYRLVARSQLRALE
                     IDTAYLKGNAAGWASVSVRDGEDGDWREILPRTRLQPDTNHRFVLPDPAVGTHARVDIH
                     PDGGISRLRLFGTLTDRGTAALEARRQELGG"
     gene            complement(26513..27265)
                     /locus_tag="IE148_RS01640"
                     /old_locus_tag="GCM10010287_03310"
     CDS             complement(26513..27265)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (14-185). E-value: 5e-14. Score:
                     44.5. Matches aSDomain:
                     nrpspksdomains_IE148_RS01640_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125487.1"
                     /locus_tag="IE148_RS01640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03310"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_189363503.1"
                     /sec_met_domain="adh_short (E-value: 1.7e-36, bitscore:
                     121.1, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTQITEKTLLGRAALVTGGSRGIGAATALRLAREGADVAVTYVS
                     GKEAAEDVVRAVEALGRRAVALRADAGDPEEAASAVTTAVRELGRLDVLVNNAGVGVLG
                     PLESLSPADVDRVLAVNVRGVFLTSRAAAAVMARGGRIVTVGSCMTQRVTGPGGTLYAM
                     SKAALVGLTKALARELGERGITANIVHPGPTDTEMNPAGGPYAAGQAAATALGRFGTAE
                     EVAETIVHLADAAYVTGAEVAVDGGHAA"
     aSDomain        complement(26711..27223)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE148_RS01640_PKS_KR.1"
                     /evalue="5.00E-14"
                     /label="IE148_RS01640_PKS_KR.1"
                     /locus_tag="IE148_RS01640"
                     /protein_end="185"
                     /protein_start="14"
                     /score="44.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="ALVTGGSRGIGAATALRLAREGADVAVTYVSGKEAAEDVVRAVEA
                     LGRRAVALRADAGDPEEAASAVTTAVRELGRLDVLVNNAGVGVLGPLESLSPADVDRVL
                     AVNVRGVFLTSRAAAAVMARGGRIVTVGSCMTQRVTGPGGTLYAMSKAALVGLTKALAR
                     ELGERGIT"
     CDS_motif       complement(27155..27220)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE148_RS01640_0001"
                     /evalue="1.40E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE148_RS01640"
                     /protein_end="37"
                     /protein_start="15"
                     /score="17.7"
                     /tool="antismash"
                     /translation="LVTGGSRGIGAATALRLAREGA"
     misc_feature    27354..27364
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            27444..27881
                     /locus_tag="IE148_RS01645"
                     /old_locus_tag="GCM10010287_03330"
     CDS             27444..27881
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0004521 - RNA endonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019547579.1"
                     /locus_tag="IE148_RS01645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03330"
                     /product="ribonuclease domain-containing protein"
                     /protein_id="WP_086704937.1"
                     /transl_table=11
                     /translation="MRFPPRAARSGAAASLLSALLLGGGGALSAPAAHAAPALPVAVSA
                     TPSVLAVGDICYGDLPSEAHDTLDLVEQGGPFPFEQDGTVFQNREGILPGQDTGYYHEY
                     TVITPGSPTRGARRIVTGEEYHEDYYTADHYASFDLVDHSC"
     gene            complement(27905..28108)
                     /locus_tag="IE148_RS01650"
                     /old_locus_tag="GCM10010287_03340"
     CDS             complement(27905..28108)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972674.1"
                     /locus_tag="IE148_RS01650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03340"
                     /product="hypothetical protein"
                     /protein_id="WP_086704938.1"
                     /transl_table=11
                     /translation="MKKLLEIVGFLAVLQGVAGLVTEFTDWNWGLVRRAGFLAGYEIYA
                     SVALLVLGVALFALAETRKPGG"
     gene            28288..29538
                     /locus_tag="IE148_RS01655"
                     /old_locus_tag="GCM10010287_03350"
     CDS             28288..29538
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431808.1"
                     /locus_tag="IE148_RS01655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03350"
                     /product="histidine kinase"
                     /protein_id="WP_189363504.1"
                     /transl_table=11
                     /translation="MTDDKAARTAPAYTGPSWFFPSALIHELDPDASRSGRRPRRTARD
                     WVVDFSCFLLAVLIGLLGAEALRDNTDLPHAVAVLDQVLGALSCAAVWLRRRWPFGLAV
                     AMVPVGFLSETSGGVAIIALFTLAVHRPFRYVAWVAGAQLALTPLYFWWRPDPDLPYLA
                     VVVLLLVLTVATVGWGMFVRSKRQLMLSLRDRARRAETEARLRAEQAQRLAREAIAREM
                     HDVLAHRLTLLSVHAGALEFRPDAPRDEIARAAGVIRESAHEALQDLREIIGVLRAGDS
                     EDAGRPQPTLAALDTLVAESRQAGMKVTLDQRVTHTASVPASVGRTAYRIAQEGLTNAR
                     KHAPGTEVTVSVSGGPGEDLTVRVHNPPPEGDVPPVPGAGQGLIGLTERATLAGGSLAH
                     GRTPEGGFEVRARLPWR"
     gene            29750..30430
                     /locus_tag="IE148_RS01660"
                     /old_locus_tag="GCM10010287_03360"
     CDS             29750..30430
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006380409.1"
                     /locus_tag="IE148_RS01660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03360"
                     /product="response regulator transcription factor"
                     /protein_id="WP_189363505.1"
                     /transl_table=11
                     /translation="MTRIRVLLVDDDPLVRAGLSFMLGGADDIEIVGEAADGAEVSALV
                     DRTHPDVVLMDIRMPSVDGLTATETLRGRDDAPQIVVLTTFHADDQVLRALRAGAAGFV
                     LKDTPPAEIVAAVRRVAAGDPVLSPAVTRQLMAHAAGDPGPGDGRRSRARDRVAALNDR
                     EREVAVAVGRGLANAEIAAALYMSVATVKTHVSRILAKLDLNNRVQIALLAHDAGLLEE
                     TDSP"
     gene            30463..30897
                     /locus_tag="IE148_RS01665"
                     /old_locus_tag="GCM10010287_03370"
     CDS             30463..30897
                     /EC_number="3.1.2.-"
                     /GO_function="GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1144: thioesterase superfamily protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019521853.1"
                     /locus_tag="IE148_RS01665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010287_03370"
                     /product="PaaI family thioesterase"
                     /protein_id="WP_048455606.1"
                     /transl_table=11
                     /translation="MTPPPELDLAAARKLLDAQPFSRLLGARVTAFGDGGATLEIDIRE
                     DLHQQNGFLHGGVLAYAADNALTFAAGAVLGPSVLTGGFSVQYLRPATGRTLRARATVV
                     HAGRRQAVTRCDLLTVTEDDEETLCAVAQGTVLPVTARPS"
ORIGIN
        1 gcccgcggct tcgcccccct ggacacgttg gtgcgggaac tggggctgct cgacggcgcc
       61 cccggcagct tcatcgagtg ggagaacagg cacggcgccg tccggcgggc ggacagtacg
      121 ggcaccggcc tcacgctgac gcgcgacgcg acgcaggaac cggtgaaccc cggacaactg
      181 gaggccgtgg cccgcaccag cgttcagtga gccgctgcga cgcggccact gaccggcggt
      241 caggtacggg agaacggcgc ccaccgggcg agcccgaaac cgctgccctc ccgccggatc
      301 tcgaaggcgc cctgccccgg cagatgggcg gggaacacca gggcgcggtg gtcggccgcg
      361 tacgcgaaca tccgtgcgcg gctggcacgg gcgccctcct cgtcctcctc gaagcagctg
      421 ttcagatgcg gttcgtggat ctggatcgcg ccgtgcagca ggtccccggc gaacaccgca
      481 cgctcgcccc cggactccag gtggacgacc gccgaacccg gggtgtggcc gggggcgggc
      541 tcgagccgga ggttgccgtc gatgacgtag gagctctccc aggtcgtgac gagccccgcg
      601 tcgatcacgg gctggacgct gtcctcgtac acgttctggt tgccccgccc gaactgtgtg
      661 cggtgcaggt tgtcgggatg ccagtacgtc acgtcgatcg ccggcatcag atacgtggcg
      721 ttggggaagg tgggcaccca gtcgcggccg tcgaggcagg tgttccagcc gacgtggtcg
      781 tcgtgcaggt gggtgttgac gacgaggtcg acgtcctccg ggcggacgcc ggcggcggcg
      841 aggttggcca ggtagccggt gtccagatac gaccagatcg gttgcagggg acggtacttg
      901 ccgttccccg cccctgtgtc gatgacgacg acccggccct cactgcgcag cacccacgac
      961 tgggtggcga cccgggtgag atcggtacgg gcgtcccagt ggtccgggtc cagcagcgcg
     1021 gcgtgccgcc tccactcctc cggcgtagtg ccgggaaaga acacgtcggt cgtcatcggg
     1081 gagatgtcgg agaactcgat cacccgggtg atctcgacgt ctccgagacg gagcgtggtg
     1141 acctggggcg atgctgtgcg ggcggtgggc atgggtctcc ctcgtacggg gccggggcag
     1201 ggtggcggac cgcttccacg gagaacgggg cggccgtacg accgactctg cggccccccg
     1261 ccccgcggga ccagccccgc ccctgcctac ccctgacagg tgcaggctgc gggacaccgc
     1321 tcccgcgcat actgggcgca tggaccgcac atcaccgctc ggcgcgttcc tgaaggcgcg
     1381 gcgggcgcgg ctgagccccg acgacgtcgg cctgccccgg tacggggacc ggcggcgcgt
     1441 ccccgggcta cgccgggagg aggtcgcgct gctcgcgggc gtcagcgccg ggtactacac
     1501 gcggctcgaa cagggccaac agggcaacgc ctcacccgaa gtcctcgacg cgctggcacg
     1561 ggcgttgcac ctgtccccgg ccgagcggga ccacctgcac gacctgtccc cgacgaccgg
     1621 tcaccgcacc cgcccggcca catccggcga cgacgagaag gtgtccgccg acctgcgtac
     1681 attgctgacc acgatggccg tccacgtgcc cgccctggtc gtcggccgcc gtaacgacgt
     1741 actggcctgg aaccgcaccg gccacgccct cctcgccgcg cacctggact tcgccgcgcc
     1801 cgaatccccg ggcacccggc ccaacctgtc ccgcctggtc ttcctggacg cccccacccg
     1861 cgccctctac cgcgactggc cggcgaaggc acgcgcggtg gtcggcaacc tccggatcct
     1921 gaccgcccgc aacccgggcg acacacacct cgccgcgctg atcgccgaac tgacggcgct
     1981 gagccaggag ttcaggagca tgtgggacgc ccacaccgtc gctccctgtg gccgcgacgt
     2041 gcacacgctc tcccacccgg ccgtcggtga actgaccgtc acccagcaga cgttcgacgt
     2101 cccgaaggag ccgcaccagt ccctggtcac cttcacggcg gaaccaggct cgccctcggc
     2161 ggtggccctg gaagcactca aatgccgtgg acgaatcgtg gacacccccg tagcgtgtgc
     2221 tcccacgccc tgactcggac ggaaggaggc gagtgccgtg cggttcccac ctttccagcg
     2281 ctcccttccc caccgtcccg gcgtgcgcga cgagttctga ccgggagcgc tccgagcggc
     2341 agcaggcgac cctgctgcac gcatcctgga ggatcccatg accgatctgg tcatccgtac
     2401 gctctccgcg agcgacgccc acctgttcga cgcgcttccc gacccgctgg gggcccgtga
     2461 ggcccaccgg cgcacccgct tccgccccga ctggaagcgc gtcgtcctgc gcgacggcga
     2521 ggtcgtggca cgcggggcgt ggtggggcgg gcccgacgac ccggagcccg tcaacatcaa
     2581 ctggttcgac gtggccgagg gcgaggagaa ggccggagcc gaactgctgc gctccgcgcc
     2641 ccggcaggtc gagctcgaga tcaacctgcc cggcggctgg cgggacgacc ccgtcctgcg
     2701 cgcggccgcc gaggcgcgct tcaccgccgc acgcgccgcc ggctacgaac tcctggtgga
     2761 acgcttcctg taccgctgga cccctgaccg gggcctcccc gaccgccccg gccgcctgaa
     2821 cttccgcccc gaacccgacg acaccgtctt cttcgacgcg ctgcgccgca tccactccgt
     2881 gaccctggac gcccacgcgc tcaaggccgt cgaggagggc ggcctcgacc aggcggcgca
     2941 ggaggagctc gacttcttcc actggtgccc gtccccgcgt gactggtggc gcaccgcgca
     3001 caccccggac ggcgacctgg ccggcatcca catcccggcc cacaacccct cgggccccac
     3061 catcggcttc atcggagtgg tcccggaaca ccgcggccac ggctacgcct acgacctgct
     3121 cgtcgaatgc acccgccacc tggtcgaaca gggggcggag cacatcagcg cggcgaccga
     3181 ccggggcaac atcccgatgg ccgcgtgctt cgccgaggcg ggcttcccgg tcgtcaggga
     3241 acgggtcaac ttccacccgg cgacggcgac caccgccgaa ctctgacgcc gtcgcgtgga
     3301 cgtaccgcgc caacccgtcc gggccctgga cccggccgga tgagccccgc ggtgggtgcg
     3361 ggcctgaggg ccggcaccca ccgcggagcg atgagccggc actactggta gcggatgcgg
     3421 cgagggacag cgtggtactg gccgtattcg ctgaggtagt cgtcgaggag ttcacgcagt
     3481 gtgccggcct ctgccgggag cgacgccgag aaggcgtccc atccggtgaa ggtcagctcg
     3541 tacggcaggt cgacgaggcc ggtgaccgcg tcccagaaag cgttccagtt ccggccgtag
     3601 aagtcgggga actgcagctc cctctgcagg agtcgttgga ggccctcggc gtcccgtacc
     3661 tcggtcaggt cgatgaccag tgagtcgggg accgtgggtt ccacttcgct tgttccgtct
     3721 gtctcgtccg tcatcacggc caggatcttt cagtaggtgc cgacataatc gacggtcttg
     3781 tagtggtcgg tggtcacgta cagcaggccg tcgtcggagt agagcagccg cgtgcctggc
     3841 tgcttggagc gcttcatggt attggtcagg ccgacatcgg cctcgtacca cacacgtccc
     3901 gactcggtgg gcaggccgat ggaggcgggg tcgcggaaga tgtcgccgcc gatctggccg
     3961 cccggcacgt ggttgccgag ggccttgccc ggttcccagc ccttctgggc ggcctggctc
     4021 ttcgtcacgt agttcgaagg gagcttgccg gtcttgcgca ggctgtcgat gagagggttg
     4081 gccttctccg cggtgctcag tactgcggtg agccgggagg cgttgtacag gctgtcggcg
     4141 cccttgtacc cggccttcat cgtgcgcagg atgacgactg ctcccacggc gcggtccagg
     4201 ccggacagag gttcaccggt ggaagggtgt ccaggttgga gaagtcgaag tcgatccggc
     4261 cgggggtgat gtggttcagc tgctcgaagc ccttggccat gttcttgacg gccttgtcgg
     4321 tctcggccag ggccttgttc gcctcgctga tccccttgtt catctgggcc atgccacggt
     4381 tggcgcggtc gatgccggcg tttgcgtgct tgagtccggc gttgacctcc gccacaccct
     4441 ggttcatctg gtcgagcccg gagttcattt gcgccatgcc ggcgttcatg gtgtccaggg
     4501 cactcatgat gtccttgtag gtcttgccga cctccagctc cttgatcagg tacatcgtgt
     4561 ccctgagcag tttggcggtc gacttggtga ccttcaccgc ctcacggccg aatgcggcgg
     4621 cggccttgcc cttcttctcc gccttcgcgg cggactggag gaacttcgta cgaagcgcct
     4681 cgtcggtcaa cagcagtgac gggtcatcca gcgccgcgta cgccttgacg gtggcgtcgt
     4741 aggcgtactg ggcatcgagc tgtccgtcgc gggcctcatg gatgaggtgc agtaccagaa
     4801 accaggtgac accgcgttcg gctatctgat ggaccaggtc ctcaaggcag gccgggcgct
     4861 cggtcagcgg tttgtccagg cattcctgca ccgacgccgg cggtcttctt cagggcgtcc
     4921 ctgacacagc cgatcttctt cagaaggttc aggttctcgc aggaggcgag cgggctcgat
     4981 gcggcggtgg ccggctgtgc gggcgcggcg gcgatggttc cggtcaaggc caggaccatt
     5041 gccaggacgg cagtgacgat ccgggatacc ggcttgttct gtctcaattg ttcccccgcg
     5101 tcatcaggac tgcgctcgca ccaccgtagg aggtcactcc tggtcaggga gtgggaggca
     5161 ggccggagac gccgtttgat gaaaaatgtg cacgcgtatg ttactggaca gtagggcagt
     5221 tgtcgccaag ggggccctct gcgtcgagac cgtgcaacag ggtccggccg ccgaagtagc
     5281 gcccaaggcc atgacgtccg ctcgatgcac cccttgaatg gggacgacaa cagcttctca
     5341 gcgatcgaca acccggcgtg tgtcctgcgg ccaagacccc gtccttacga tccgctgtac
     5401 gagcctgaag gcctcgtgca cggggacggt gtccgcgtcc gggtacgcgt cgtgctgccc
     5461 gttggagagg acgtatccgt cactcgatcc ctcggcccca gggtccacgg catgctcgcc
     5521 cggaccgccc tcttcttcga acagcatcac catggcccgc tcgttgttcg tcacgaaggc
     5581 cagcgatcgt ccggacgagc tggtcatcca cgtctcgaga tgcccgctgt tgatcctcga
     5641 ccgaagtccc cgcaccaccg tcgcggacga cacaggcaca aggctgctgc catcgatcac
     5701 ccacgtctcg gtcacgcgga cgaccatctc acgcacggtc acacggccgt cgtcggcggc
     5761 gtccccgtct gtgcggccag ggcggcgagg agccagtcgt gggcggtgcc gggtgtcggt
     5821 tcgggccgtc ggcccggctc ggtgacgacc tcggccacca gctcccagta gcggtcgatc
     5881 cgcgcgtcgg tcgcgagctg cccggccagc ccgcgacgga actgctcgcc gtcccggacg
     5941 ccgtacgcgc cggtgtacgc gtcgacgaag cagtccagcg cctcaccggg ccgcggctcc
     6001 cggcccctcc gcagctggac acccgccagc tcgtacgcct ccgccagccc cgcgtacagc
     6061 acggccgccc cctgggcgcc gacggcccgg tgcgcctccg gctggggctg tgcggcgccc
     6121 ggacacgggc cgagagtgag cgcgttgagc cgggcgaagg cgaggacctg ggccggagcg
     6181 gggtcgtccg gcggctgcgg caccgcgacg tccaggaacg cgtcgaccga ccgccggggc
     6241 atccgcggcg gaagccagcc gcgccagaag cggaccagcg gggccgtgct gggcgggacg
     6301 gacaggcccc cgatcagctg gagccggtcg gccctctccc cgggcgtgga ctcctgcacc
     6361 agacggagtg ccgcctccct ccaccgcaac gaccgtatct cggtgccgag ttcacgcaga
     6421 cgctccgcga ccgcgccttc cagtgcctgt cccaggccgt cggtcgcgtc ctcctcgtcg
     6481 aggacgcgcc gcacctcggg caccgagagg ccgagtgtgc gcagggagcg gatcaggcgg
     6541 agcctgtcga gcgcgtcgga gccgtagcgc cggtgtccgc ccgcgctgcg ggaggcctcg
     6601 ggcagcagcc cgccgtcgga gtagaagcgg acggtcttga cggtgacacc ggcccgcgcg
     6661 gccagctccc cgatgcccca cagatcgtcg tacctcgtgc gcacgcttga acctccctca
     6721 aggggagttc ctacggtacc ggcgagcggg accggtgacc ggaccggacc gtcgagtccg
     6781 aaggggaggg ccatgaccat cttcgtcctg gtgccgggca tgttcaccgg cgcgcatgtc
     6841 tggcaggaga ccgccgaccg gctgacggcg gccggcgccg tggcgcatcc cgtgcggctg
     6901 accgggcttg acgccgcgct ccgcccggcg ggcggtgaca tcgacctgga gacccacatc
     6961 gcggacgtcg tcgaggtgat cgactccctc ggccggaccg gccggaagct cgtgctggtc
     7021 ggccacgact acggcatcca tcccgcgctg ggcgcggccg accgcagggc gggacgcgtc
     7081 gaccggatcg tgtacctgga ctcgggcatg ccggggaacg gcgtacccgc cgtggccgcg
     7141 gtgcccgacc ggtccttgcg cgatcggacg gccgcaacgg atggcaaggc gctcccgcct
     7201 ccggccaccc ccgaggactg gcgccggtgg ggcagcaccg agggcgtgcc cggcccggcg
     7261 cttgaccagc tcacggccat ggccgctccg cagccgatgg ggaccctgct ccagccgctc
     7321 aggctgaccg gagcggtgga cccggtgccc gccaccggca tcctgtgcac cggcaacggg
     7381 gcgagcatcg agatggtcca gatgatggtg gaccggggcg acccgacact gcgggaactg
     7441 gccgatgcgc gggtcgcctt cttcgaactg cccaccgggc actggccgat gctctccatg
     7501 cccgccgaac tggcggacgt cctgctgcgt gccgcggccg gcgaggggca ccgcctggca
     7561 cccgccgacg cttcggaacc gcccgcacac ctgcgtccct tcccgctgga ggtccccgag
     7621 gccccgcggg agcggcacgg gaacgtcgac ctgtacctgc cgccaggcgc cgaagcgccg
     7681 cgccccgcgg tgctgttcgt gcacggcggc cccgtccccg ccgacgcccg ccccacaccg
     7741 agggactggc cgaccctgag gggctacgca cactgcgccg cggcgggcgg cgcggtggcc
     7801 gccgtcgtcg accaccgtct gcacaccctg gacgactacg agcgcgcggc cgccgatgtc
     7861 gccgccgcca tggaacaggt gcgggccgat ccccgcgtgg acgcggaccg ggcggcgctg
     7921 tggttcttct ccggcggcgg tccgatcgcg gccccctggc tggacgcgcc cccgccctgg
     7981 ctgcgctgcc tggccgccac ctatgcggtc ctcgggccgc tgcccggctg gggactgacc
     8041 gacagccgct tcgacccggc gcgcgcggtg gcgcacgccg gcggcctgcc cgtcgtcctc
     8101 acccgcgtcg gactggagac gcccgcgatc gccgccaccg tcgagggatt cctcgcctcg
     8161 gcgaaggagt gcggggcgga cgtggaggtc gtcgacgtac cgcgcggtca ccacgccttc
     8221 gagaccgtcg accccacgga cgagtcccgc gacgcggtac gccgtgcgat ccgggcggta
     8281 ctggaccgcc tgggcgtgcc tgacacccac cagggcttcc cgcccgcggg gtgacgcggg
     8341 ggcgcgtcgg agcgacacgg cgcgccggag tgggagagcg ggccctccag agggcctgag
     8401 gcgtgtacga ctcgtaccgc ccggagggcc tcgtccccca cccgtaagga acccctgtgc
     8461 acgacctcgc cgactccgtc gagtcgaggg catctcgagc gaccagcgcg cggtcggcgc
     8521 gggtggccga cagaccgggc cgtgtgccgt cgcctactgc cggtacccgc tcaggaagcg
     8581 gccgatgcgg ccgatcgccg cctccaggtc ctccgcgtgg gggagggtga ggatgcggaa
     8641 gtggtcgggg gagggccagt tgaagccggt gccctggacc acctggatct tctcccggag
     8701 cagcaggtcc aggacgaact tctcgtcgtc gtggatcttg tgcaccttcg ggtcgagacg
     8761 cgggaaggcg tacagcgcgc ccttcggctt cacgcagctc acgcccggga tctcgttcag
     8821 cttctcccag gccgtgtcgc gctgttcgcg cagcctgccg cccggggcgg tgaggtcccg
     8881 gatggactga cggccgccca gcgcggcctg aatggcgtac tgcgcgggcg cgttggcgca
     8941 caggcgcatc gacgccagca tggtcaggcc ctcgaggtag tccttcgcgt gctgcttcgg
     9001 tccggtgacc accagccagc ccgagcggaa gcccgccacg cggtacgtct tggacaggcc
     9061 gcagaaggtc agcacgacga ggtcgggggc gagcgcggcg gccgagtggt gcacggcgtc
     9121 gtcgtacagg atctggtcgt agatctcgtc cgcgaggacc atcagtccgt ggcggcgggc
     9181 caggtcgagg atgccctcga cgacctcctt cggatacacc gcgcccgtcg ggttgttggg
     9241 gttgatgatg acgacggcct tggtgcggtc ggtgatcttc gcggccatgt cgtcgaggtc
     9301 cgggtaccag tcggaccgct cgtcgcacag gtagtgcacc gccttgccgc cggacagggt
     9361 ggtcaccgcc gtccacagcg ggaagtccgg ggccgggatg aggatttcgt cgccgtcctc
     9421 cagcagggcc tgcaccgcca tggacaccag ctcggagacg ccgttgccga ggaagacgtc
     9481 gtccacgtcg acctccaggc cgagcgtctg gtagcgctgg gcgaccgcgc ggcgggcgga
     9541 gaggatgccg cgcgagtcgg tgtagccgtg cgcctggggg agcatccgga tcatgtcctg
     9601 gaggatctcc tccggcgcct cgaaaccgaa cagggccggg ttgccggtgt tgaggcgaag
     9661 cacgctgtgc cccgcctcct ccagcgcgtt ggcgtgctcg atcaccgggc cgcggatctc
     9721 gtaacagacc tcgctgagct tgctcgactg ccggaactcc atgcgcccct ccggtttctg
     9781 gtgttacttg gttttaccaa gtgggtgctt ggaaagtcca acgacatgtc tagactgcga
     9841 ggcatgccac ctcgccgaag ctacgaccag tactgctccg ccgcccgcgc gctcgacgtc
     9901 gtcggcgacc gctggaccct gctgatcgtc cgggagctgc tggccgggcc gcgccgctac
     9961 accgacctgc acgcggacct gccgggcgtc agcacggacg tactggcctc acggctgaag
    10021 gacatggaac gcgacggcct caccacccgc cgccgccttc cgcctcccgg cgcggtctac
    10081 gtctacgaac tcaccgcgcg cggacgtgag ttgctgcccg tcctccaggc gctcgggacg
    10141 tggggccggc cggagctcgg cgcacgccgg ccgaccgacg cggtccgcgc ccactggttc
    10201 gccctgccgc tgctgcgtga actggagggc gacggactcg tcgaagtacg cctggacgag
    10261 ggctgcttcc acgtccacgc gggcgcggcc gacagccccg tctacggcga cggcccggcc
    10321 cctcgcgacc cggacgcggt cctcaccctc gacaccccgg cgtgcatcgc cctcagccga
    10381 ggcgatctgt ccctgccgga ggcgatccgg gacggccgcg tcgagatcac cggcgacagc
    10441 ccgctcgcca agcagctcag ggaggcgtga gaaggcgctg cggcgcccgc cctcacgcct
    10501 cgacgaaccg agccgcgagc gccggacggc ggccccctct gcctccgccg gccggcttac
    10561 gttcggcacc caccgcacgt gatctctgcc ggaacacggc aatgatcagg tggcgggggc
    10621 tgtggcagcc tcccggacat ggggtggagc ttcaaggtgc acgggggaat cgcgctcgcg
    10681 atgagcgcca cggcgttgtt gttggccttg ctttcgtggg tgccggggat gacgttgtcg
    10741 ctcaccgacg tggactggct ggcagtcgtg gtgctcatgc tgcccgttgt tctggccgca
    10801 ggggtgcgcg tgctgctgac cgggtccgac aagaagacgc tgtggcgggc cttctggtgt
    10861 ctgccgggcc gattgcaggc gacgctgggc gtgctgttca tatcgggctt cgcgctgttc
    10921 ttcatgggca tgtccaacga caccaggcaa cagacagaaa tgatcaaaga cggtcgctac
    10981 tacgtcttcg acatgaccac ttcaaagcgg gccctggtgg aggtgccacg cagtcagtac
    11041 gagaaggtcg ccagggagga ccagcggccg atgttcgccg gcttcacatg gctgtgcgcc
    11101 gtcagcgcct tcggtgtctt caccgccggt gaactgcgcc gagccgatgc ccggtccgga
    11161 tcggtggacg cggccacata gaggggcgca ccgcaacttc gacagatccc gtcgatgggg
    11221 ctaccttcac ccggccctgg gcgagtccgc gcccaggtgc accccttcga agccccccgc
    11281 taagggagac gcatgccccg cctcgcgctc tacaccttcg gcgtcctcaa gtcccccctc
    11341 tccgaccccg gtcccatcac ccgcgagttc tacgacatcg gtgaggccgt ctaccggagg
    11401 atcagcgcgc accccggtta cctcggccgg gccgaaccgg agggcggtga gcacggcgtg
    11461 ctcttcgggg cggactgggg tgcgtggggc gagttcgccg taccggcgtg gtacgccaag
    11521 ggccgtaccc ccgacaccac cgccctggcc gcgaccctct ccctctggac cgacctgcgc
    11581 tccgcccgcg acgccgtcca caccgggctc caccgcgagg cgctgaccag gcgccacgac
    11641 tggttcgaga ggtcgcggca cccgacgcac gtgctctggt gggttcccga ggacgcgacc
    11701 cccacctggc gggagggcgt cggcaagctg gagcgcctgc accaccatgg ccccgcaccc
    11761 cagcgcttca ccttccctca gccgttcact ccggagggcg ccccgacctg cggctgaggg
    11821 cccggacagc cggaaggccc gcacacggcg ggccttccga accgaaacgc gaaacgaggc
    11881 tcacgccccc ggcgggacgt gccgcgggcg gcccggtcct cgcgtcaggc ggtagccgca
    11941 cacacccgcc agggccgcca gcgcgccgcc gatcgccgtc cagatccagc ggtccgacca
    12001 ccagcccgac gtccagccgt cctccggttc gaggtcggcc aggacggcgg agggagagtc
    12061 gtccgactcc tcctgcggac gggaggcgac acccggcacc aacggctcgg acagcgagcc
    12121 gtcgaccgcc gtcgcaccac ccatgtcctt ggatttgacg cgcagttcgg cgtcgaccgg
    12181 cttgcccagg tcgtccgccg acagtttcag ggccgtcagg cgcacgtagt acgtgccggg
    12241 cagcggatcg ttggcccacg gctccgacca ggcgcggacc gtgcgcagca cgcacgccag
    12301 ttccacgctc gccgcgcccg ccccggcggt gcgggtctgc gcgccgtact ggcaggcctg
    12361 ccggcggcgc agcccgtcgt acacgtcgac ctgccacgtc tgggcggcgt ggctctccgg
    12421 cagcttcacc gtcgcgcgaa cggtgggccg ctgtccggcg tccgcgggga acgaccagta
    12481 cagatagtca cccgtggagg cccgcgccgt ggcggtctgc ccctgctcga cctccgtcgc
    12541 ggtgcggaac gacgtccccg cgcgggtggg cccgccgccg tcgccggaag cctccgggga
    12601 cggggaggaa tccgccgcgg cgggcgcggc ggccaggccc agcgtcagca gggcggcact
    12661 cagtactcgt acggcgcgca tcagttggtc ctccagacag cgacccgcca gcgggacagc
    12721 cagccccaga cgagaccggc gaggaagccg gtcacgacca gcgcgccgag cagccaccag
    12781 ccccggccga ggccgaagga ggcgacgtcg gacgcgtcgt ccgggccgtc gacgacgtcg
    12841 accgtcagct ccagcggcag gccgggcgtg gtcttcaccc cggcgtccgc cgagaaggag
    12901 gtggtcacgc cgaggcacac cgtctccgcc gcgggcttgc cgctgtcgtc gtcgtccagc
    12961 tccggcttgg ggtggcgcag gcccgtggac accacgtccg tacggccgtt gcccgtggcc
    13021 tcgccgcgca cgatctcccg gccgtgcacg gtgaccgcgc gcatcagcac accgtggtcg
    13081 gggcgtacgg cgcggtccgc ggcgatgctc accgaggcgc gcagctcctg cccggcgagc
    13141 agctccacgc ggtaccagcg ctgctggccg aactcctggc ggtcggtgta gagaccggac
    13201 cgcagctcgg gcgcccgctc gcacgcgtcg gcgccttcga cggccaccgg ggtcaccacc
    13261 ggctcggccg cgcggtcgac caactcgttc acacggtcgg tgagttcgtc ctggtgctcg
    13321 atggaggtgt acgttccgcc cgtcgcctcg gcgatgcagc tgagctgccg gctcagcttg
    13381 gcgttcggca ccagtcccag cgtgtcgatg gtcaggccga tgcccttggc cgcgatctcg
    13441 cgggccacct cgcacgggtc gagcggggcg caggtgtcct cgccgtcgct gatcagcacg
    13501 atccgcttgg agccgtcgcc gccgtcgagg tcgtcggccg cctggagcag cgccgggccg
    13561 atcggggtcc agccggtcgg gacgagggtc gccaccgccg tcttcgcctc ggtgcggtcc
    13621 agcgggccga ccgggtagag ctgcgcggtg tccttgcagc cctccttgcg gtcgtcgccg
    13681 gggtagtcgg cgccgagggt gcggatgccg agctgcacct cctccggcgt cgcgtccagc
    13741 acctcgttga acgcctgctt cgccgccgcc atccgggact ggccgtcgat gtccttggcg
    13801 cgcatcgagc cgctcacgtc gaggacgagg tcgaccttgg gcgcgctctc gcccgtgggt
    13861 tcaccggcgg ccgccccggc ggggaaggcg atcccggccg tcagggcggc gagcagggct
    13921 atggcgccca ccaccggccg tgttcttctg atcatcggcg gatcctattg atcaggaacg
    13981 ccgcacatca aaacggcccg tcatccggac ccggaacgaa ggggattggg aagttccgcc
    14041 cactggtcgc ccgccgtgcc cggtgacagc cgcatcagtg tcagcgcctt cgccggcagc
    14101 ggtccgccga gcagcgccga gaggtcgtcg gtgcgcggca gatccggtac ggccgtctcc
    14161 agcgccgccc gcagggccga gcccgacccc gccgtcccgg ccagcgctcc cgccaccagc
    14221 gagccgaaca gcttgcggcg cagcgccagg gcgtcgtccg tgaccatgcg gtccggcacg
    14281 tccggcaccg ggatgccgtg ccgggccagg cgcgccggcg agacgcgcag atcggccagg
    14341 tcccggtaga ccagccgtac cggctccccg tccggcgaca gcaccacgag caggttctgt
    14401 ccgtgtgcct ccagcgccac ccccaggtcc agcagccgca gcccgacggt gagcgcgagc
    14461 cgggcgagac gggccagccg cgcgggggag cggggcaggt ccgtggccgc cagcgccgcc
    14521 accggaacca cccgttcccc ggggcccgcg tacttctccg gagactcccg cagcagcgcc
    14581 gtgaggtcgg gcgaaccggc cgccaccgcg gccggcgtgc gggtgatccg cagcagcccg
    14641 tccgtgcgct ccgccaccgc ctgcccgaag tccgacaggg ccgccgacgc ggcgaccgac
    14701 cccagggaga tgtcccgcac ggaggacgtc agccgggcgc tcaccgccgt cttgacgtgc
    14761 ggcccgtccg gcagcgcgag ggtgcgcagc gccatcagcg gatgcgccgc gagcgccccc
    14821 tcacccctga ccgaggccgc cccctgacgg ctggccgagg ccgtcccctc acccctgccc
    14881 gaagcccccg gctcacccgc ccgcttcagc acatgcgccg cctgccacgg atgcaccggc
    14941 accagcaccc ggtccccgtc ccgcagccgg tcgggccacg cccccgacac cagacactcc
    15001 cgggccggca ccggaatcag ctccagctcc accaccggcc ggtgctcggg gccgtacgcg
    15061 agctgttcgg ccaccgagaa gccgggtcgg gaacggcagt tcggatggaa agggtgcccg
    15121 tcgaccaccc gctgctccca ctcccagtcc cgcaccggcg ccgcgtcccc aggccccccg
    15181 aagtcccgct gccccgcccg cgacagcgcc aacgaggccg tgctgtgtcc cagttcggcg
    15241 gcgaacgagc ccgagtgcgg gaccgccagg tccgccatca gccgcgccgg atcgtcgtac
    15301 tccgtcccgt ccagccgtac ggcggtcacg ccggcgtttg tcgcgtacgg gtccgggacc
    15361 ggaccctcca gccgccgccc gtccgccagc cgcagcacca cccccgaccg ggtgtcctcc
    15421 cgtccggtga tccacggcag cggatcgtgg gtcagccccc gccacagccg ggtcagcacc
    15481 gccgcacgcg cgccgggcag cgcccgcgtg tacgcgggaa ggagagcggg ccgtacgacg
    15541 gccagctcct cggcgatctc ggcctcggcg gtggagggac gcggcacggg cagactcctc
    15601 ggatcggcgg aaaggtggga cgtagggagg gacgatgcca gacatactga tcgtctccgc
    15661 cggacagacg tagggaacca gaacgcgtgg acctcatgcc cccgcccgca gacgacgacg
    15721 cggcgagccg tgcggacctg gcagggcgcg ccgacgccca cgcggccgtg ccgctgctga
    15781 actgcctgct gcgcgaagtg gccgagcccc tgcccgggcc cgcccgcccg gacggcccgc
    15841 gcacctaccg cctgccccac agccggcggc tgctgcgcgt gcgcggcgcc cggcgcccca
    15901 ccgcgcccga ggtgcacacc gccggttcct ggcgccgtct cacccacgcg gaactggtca
    15961 aactcgtcgc cgaggagctc cgccggcaca ccggccgctc caactacgaa ctgcccgccg
    16021 agatgctcga cagccgtgac gccgtcgccg cgctgctcgc cgcccgcgac cgggctgacc
    16081 cgcccgacgg cctctacccg cgctccgagc agtccctgct caccggccac acccaccatc
    16141 ccgcgcccaa ggcccgcggc ggcggccccg cggccggctg gctgccgtac gcacccgagg
    16201 cgtacgcccg cttcccgctg gccctgctgg gcgtgcgcga ggacaccctg gtggacgagg
    16261 gcgacaccgc cgccctggac cgtctcggcg ccgccccgcc cggctaccgg ctgctgcccg
    16321 cccacccctg gcagctcgac ctcgccgccg acgacctcgc ccccgccttc gccgacggcc
    16381 gcctgctccg gctcggcgag acgccctggc cggtgtggcc cacggccgcc gtccgcaccg
    16441 tccacgcgcc cgccgaggac ctcttcctca agttcagcct cgacgtgcgc atcaccaacg
    16501 acatccgccg cctgtggcgg cacgacctgg cacgcctgcg cgtcaccgac accgccgtac
    16561 gggacgcctt cgcggacggc ccggcgggcg gggcctggct gagcgaccgg gggcaccgca
    16621 ccgcggactt cgccttcgag cagctcgccg tggtcgtccg tgacgggttc cgcgggcggc
    16681 tggtcccggg cgccaccccc tgcctggccg ccgccctggt ggagggtttc gccggtgacc
    16741 cgctcgcggc caccgaccgt cccgccgcct ggtgggaggc gtacctggcc cgggtggtgc
    16801 ccccggcgct cgccgccttc caccggcacg gcgtcgtcct ggaggcgcac ctgcagaaca
    16861 cgctgatcgc cgtcgacgcc gacggcatgc cggtgcaggc cctctaccgc gacgcggagg
    16921 gcgtgaagct gctcgcgtcc ccgcaccgcc ccggcggccc gcccacggtg acgcgggagg
    16981 ccgggtggga gcggctggtg tactgcctgg tcgtcaacca cctcatggag atcgccgccg
    17041 ccctcgccga ccaccacccc ggcctcgacc cctggcccgc ggtccgccgc gaactggccc
    17101 gccacgacct ccccgagatt cccgctctcc tgaccgcgcc caccctgccc gccaagacca
    17161 acctcctcct gcgctggacc gcggccgacg gcgccgacgc ccgctaccgg ccgctgccca
    17221 acccgctgtc cggtcactga gcgtgccccg cgtggaacgc gacgagaggc gaccgccgcc
    17281 ccgatgcccc agactcggga ggagggccgc agggaaggcc cccgggggga ccgccccccg
    17341 accgcgcccg gaggaggccg gcctgtgcat gacgtgccgt tctggctgtg gatcgtgttc
    17401 gtcgtcatcg tcgtcgtgtc cctcgcgatc gacctgttcg cacaccgctc ggcccatgtc
    17461 atcgacttcc gtgaggcggc ggcgtggagc gccgggtgga tcggcctggc catcgtcttc
    17521 ggcggtgtgg tctttctcgt cgtcggcacc gacgcgggcg tggagtacac caccgcgtgg
    17581 ctgctggaga agagcctgtc cgtcgacaac ctcttcgtct tcgccctgat cttcagctac
    17641 ttccaggtgc cgcgcgccta ccagcaccgc gtgctgttcc tcggcgtcct gggcgcgctg
    17701 gtcttccgcg gtctgttcct cgcggcaggc gtggcggtgg tcagcaggtt caccgccgtg
    17761 ctgtacgtct tcgccgcgat cctcttctgg agcacgtaca agatcctcaa gggggaggag
    17821 gagagcttcg accccggcaa gagcatcgcg gtccggctgc tgcgcaaggt cgtccccgtc
    17881 cgggacgagt acgcgggtcc ccacttcttc gtcaaggagg cgggcaaacg ggtggcgacc
    17941 ccgctgctcg cggtcgtcgc cgccatcgag gccgccgacc tcgtcttcgc cgtcgacagc
    18001 gtgcccgcgg tgctcgccgt cagcagcgac gtgttcatcg tctacaccag taacgccttc
    18061 gccatcctcg gcctgcgcgc cctgtacttc atgctggccg gactgctcga ccgcttccac
    18121 tacctgagcg tcggcctcgc gctgatcctc ggcttcatcg gcgtgaagct ggtcctccag
    18181 gcgacccacg agacggtcag caccgccgtc ccggagatcc cgtccctggt cagcctggcc
    18241 gtcatcgtcg tcgtcctggc cgtgtcgatc acggtgagcg tgctgcggcc gcccgccgag
    18301 caggatgaaa acacgtaaag cgggagtaaa gtggaggcat gagcagcgac cgcaggcgcg
    18361 acgggagccg gtccaccgaa ctgctgtgcg gctcgtgcgg acagccggtc gacaccgtcg
    18421 tcacccgaca caagaccatg ggcatcaacg tcccccgctg gcgggccggc ccctgccaca
    18481 accccgactg ccccgactac gtccccgaga tggtgccggc ggacaccctc cgccgggcgg
    18541 aggagcgcga gaaggagacc gggccgcctg cctgaccggc ccggcgtcgc cccaccccgc
    18601 gcggttagga ttcctgtccg acgtcgtacg aggatggggt ggcccggagc atgctgaagc
    18661 aggtcaccgc cacccgttac gtcgagcccc tgcactccgg gggttccgtg ccgggcgtcg
    18721 tcgaggcgga cgatctgggc acctacgtcg tcaagttcac cggctccgcg cagggccgca
    18781 aggcactggt cgccgaggtg atcgtcggcg agctggcgcg ggcgctcggg ctgcgcttcc
    18841 cggagctggt gctggtgcac ttcgacccgg cgatcgccga cgctgaaccc caccaggagg
    18901 tgcgcgacct gcacgccgcc agcgccgggg tcaacctcgg catggaccac ctgccgggag
    18961 cgcgcgactt cacccccgag gccgccgaga cgttcgccgt cgatccgctg gaggccgggc
    19021 ggatcgtgtg gctcgacgca ctcaccgcga acgtcgaccg caccgtgcac agctccaacc
    19081 tgctgctgtg gccgacgctc ggcgtcgccc cgccccggct gtggctgatc gaccacggtg
    19141 ccgcgctcgt cttccaccac cgctgggacg ccggcgaccc ggcgaaggcg tacgacttcc
    19201 gccaccacgc cctcggccgg tacgggcccg acgtgcgcgc cgccgacgcg gaactggcgc
    19261 cccgggtgac ggaggaactg ctgcggtcga tcgtgcacca ggtgcccgac ccctggctgg
    19321 acggcgagcc ggggttcgcc tcgcccgagg cggtccgcgc ggcgtacgtg gaacacctgc
    19381 acgcgcgggc acgggcgtcc ggcgcgtggc tgcccctcga cttccccacg gcggaggaga
    19441 tcgccgcgga gaacgccctc cgggcggcac ggacgcaaca gggccgcccg gcctggctca
    19501 agcaggtgcc cgacctgcac ggccggccgg cggtggaaca ggacgggacg gtgcacctgc
    19561 gatgacggcc gacgcgcggc gcgtggagat cgagtactgc acccggtgcc gctggctgcc
    19621 ccgggcggcc tggctggcgc aggagctgct gaccaccttc gagcaggaac tgaccgagct
    19681 ggcgctcagg cccggcaccg gcggcgtgtt cgtggtcagg gtcgggggcg aggtcgtctg
    19741 ggaccggcgc gagcagggct tcccggagcc gacggcggtc aagcaggccg tacgcgaccg
    19801 agtggccccg gggaaacccc tgggccactc ggagaggtga accgcccgga cgggccgcct
    19861 cagcccttca gctgctggta cgccggcagt gtcaggaagt ccgcgtagtc ctcgtcgagg
    19921 gcgaccttca gcagcaggtc gtgcgcctgc tgccagttgc ccgccgtgaa cgcctcgtcc
    19981 ccgatctccg cgcggatgtc cgccagttcc tcggcggcga ccttgcgggc cagctcggcg
    20041 gtgacccgct cgccgttgtc gagcaccacg cccgcgttga tccactgcca gatctgggag
    20101 cgggagatct ccgcggtggc cgcgtcctcc atcaggttga agatggccac cgcgcccagg
    20161 ccgcgcagcc acgcctcgat gtaccggatg ccgacctgca cggcgttgac cagacccgcg
    20221 tacgtgggcc tggcgtcgag cgagccgatc gcgatcaggt cctcggcctt gacgtcgacg
    20281 tcctcgcgca gccggtcctt ctggttcggc ctgtcgccga gcacccggtc gaaggactcc
    20341 atcgcgatcg gcaccaggtc cgggtgggcg acccaggagc cgtcgaagcc gtcgttcgcc
    20401 tcgcggtcct tgtccgcctt caccttctcg aaggcgacct tgttgacctc ctcgtcccgc
    20461 cgggacggga tgaacgccgc catgccgccg atcgcgtggg cgccacgcct gtggcaggtg
    20521 cggacgagga gttcggtgta cgcccgcatg aacggggcgg tcatcgtcac cgcgttgcgg
    20581 tccggcagca cgaacccggg tcctgcgtcg cggaagttct tgacgatgga gaacaggtag
    20641 tcccagcggc ccgcgttcag cccggaggcg tggtcgcgca gctcgtagag gatctcctcc
    20701 atctcgtacg cggccgtgat cgtctcgatg aggaccgtgg cgcggacggt gccccggggg
    20761 acgcccagat agtcctgcgc gaacacgaac acgtcgttcc acagccgcgc ctcgaggtgc
    20821 gactccgtct tcggcaggta gaagtacggc cccttgccga ggtcgagcag ccgcttggcg
    20881 ttgtggaaga agtacaggcc gaagtcgacc agcgcgccgg gcaccggggc gccgccggcg
    20941 tcggtgaggt ggcgctcgtc caggtgccag ccgcgcgggc gcatgacgac cgtcgccagc
    21001 tcctcgtccg gacgcagggc gtacgtcttg ccggtgcgtt cgtcggtgaa gtcgatgccg
    21061 cgggtgtacg cgtcgatcag gttgagctgg ccggtgacca cgttctccca ggtcggcgcg
    21121 gaggcgtcct cgaagtcggc gagccacacc ttggcaccgg agttgagcgc gttgacggtc
    21181 atcttgcggt cggtcgggcc ggtgatctcg acgcggcggt cctccagggc cggcggggcc
    21241 ggggcgacct tccaggagtc gtcggcgcgg atcgccgccg tctcggggag gaagtcgagg
    21301 gtggaggtgc gggcgatctc ggcgcggcgc tccgcgcgcc gggcgagcag ctcgtcccgc
    21361 cggggcgtga accgccggtg cagctccgcc aggaaggcga gggccgtctc ggagaggacc
    21421 tcctcctgcc gcggcagggg ttcggcgtcg acgatggcca gcggggacgg cgctggtgcg
    21481 gacatcagct gtcacttcct tcggcgtgcg gggggcaccg ggtgccgggc gacccgggta
    21541 cggcgggaga ggcctctgct ccgggcacag ggcatctgat cagtggatag tagtttcctc
    21601 atggtggaag ttcaatgttt tgttgatgtc gagagtcctc actcaaggtg cgccagatcc
    21661 gcctccgtgt cgatgtcgta cgcctccgcg acgtcgccgc actcgaccag ttccacggcg
    21721 tccgcgtgct ccctcaggta ggcgcgtgcc ccccggtctc cggtggcggt cgcggcgatc
    21781 cccgcccagt gtccggcgcc gaacagcacc ggatggccgc gtacaccgtc gtacgccgcc
    21841 gaggccagcg agcgcggcga ccggtacgcg tgccgcaccc gggccaccgc ctccgggccg
    21901 atccccggct ggtcaaccag cagcaccagc gcggcccgcg cgcccgcacc ggcgagcgcc
    21961 ccaaggccgg cccgcaggga cgtgcccatg ccgtgctccc agtccgggtt gtccacgagc
    22021 gcacagtccg gcagctcggc acgggcgcgc acctcatcgg cgcgcgcccc caataccacg
    22081 tgcacgctcg cgcagccgcc cgcgcgcagc acctccgccg cgtgctccac gaggagccgc
    22141 ccccggtggg ggagcagggc cttggggcgc ccgccgagcc ggcgtccgcc gccggccgcc
    22201 agcaacaggc cggccacccg gttctcgtcg tccgtcatgc gtcctgcata ccccacccga
    22261 agccgcccgt ccgggcgtcc ggcggaaggg tgcctcgggc cacggtgtca cgctccggaa
    22321 caagtcgatg acgcagcggg ctggcgcaaa ggccccggga tggcgtttac tggcgcgcac
    22381 cggtccgcgg gggcgcgtgg gaccggccag gggaggcgca cgacgacctg ccagggggag
    22441 gactgtgttg cgaggcgtgg accagaggtg tgtgcccggc agtcaggtgg atccgcgtgt
    22501 ggcggagctg cgctccgccg tggcccggtt acgccgccaa ctggcggcac atcgtgtgga
    22561 gttccgggac cggggtgtag cggaggaggc gctcgccatg ctggcaggac tggccgccgc
    22621 cgaccacccc gacatcccgg tgctgcgccg ctccctgctg ctcgtcgccg gagccatcgg
    22681 ctcggtgagc gcgctggggg aggggctgcg tcaactccgc gaggcggtcg acctcttcgg
    22741 gacgtcacct cgcgcatgac gtacgggcgt tcgaggtgta gccctcgcgg gtgatccgtg
    22801 cggtgcgcct ccgacgcagg gtgagtgcga ggtccctacg ggcccggggg agggcggtgc
    22861 cggtgccccg acctcaagac gggcgcggcg agcctcgcgt ccgacgcgcc cgcagtgcgc
    22921 cctcaggcgg ccgggcctcc tcccgggtta gccagcgcct ccgacagttc gcgcgcgatc
    22981 tcctgcagca ccggcacgat ccgctccgtc gccgactccg tgacgcggcc cgccgggccc
    23041 gagatcgaga cggccgccgc cgtgggcgcg tccggcaccg ggaccgccag gcagcgcacg
    23101 ccgatctcct gctcgttgtc gtcgatggcg tacccctgcc ggcgcacctc ctccagtgcg
    23161 gcgaggaagc cctcgggtgt ggtgatggtc ctgtccgtgg ccgcgggcat gccggtgcgg
    23221 cccagcagcg cccgcacctc ctggggcggg aacccggcca gcagtgcctt cccgacgccc
    23281 gtggagtgcg gcagcacgcg ccggccgacc tcggtgaaca tccgcatcga gtgcttcgac
    23341 ggcacctgcg ccacgtacac gatctcgtcc ccgtccagca gggccatgtt cgccgtctcg
    23401 ccggtctcct ccaccagccg cgccagatac ggccgcgccc aggtgcccag cagccgggac
    23461 gccgactcgc cgaggcggat caggcgcggg cccagcgcgt accgccgatt gggctgctgg
    23521 cgcacgtagc cgcaggcgac cagcgtgcgc atcaggcggt ggatcgtcgg cagcggcagg
    23581 ccgctgctgg cggacagctc gctcaggccg acctcgccgc ccgcgtccgc catccgctcc
    23641 agcaggtcga aggcgcgctc gagggactgc acgccgccac tggcggcggg ccgggcggag
    23701 tcggtggtgc tggcgctgga cgtcggcacg gcgcgttcct ttcggtgctg gcaggaggtc
    23761 agaagcctac ccggcggccg gtcggcggcc cgcttgtgcg gagctacgtt ctgtttgacg
    23821 gaatggtaat tccgctttgt ggaaacgtcc agagatggtg ctcgcgccgc cgtggcggcg
    23881 ggagcaccct tgacgcagtg aggtccgaag gcaacactcc ttcaacagaa cgttgaattt
    23941 tccggcggac cgcaggaggc tccgggtgcc cgacgtccaa ctggtgctgc gctcgacccg
    24001 cgtcgtcacc cccgagggga tgcgcgccgc gtccgtcgcc gtggcgggcg gcaccgtcac
    24061 ggccgtcctg ccgcacgacg cgcccgtccc cgacggcgcc cgcctggagg atctcggcga
    24121 cgacgtcctg ctgcccggcc tggtcgacac ccacgtgcac gtcaacgacc ccggccgcac
    24181 cgagtgggag ggcttctgga ccgccacccg cgcggccgcc gccggcggca tcaccacgct
    24241 ggtcgacatg ccgctcaact ccctcccgcc caccacgacg gtcgaccacc tgcgcgtcaa
    24301 gcggaagacg gccgccgaca aggcccacat cgacgtcggc ttctggggcg gcgccctccc
    24361 cgacaacgtg gccgacctgc gcccgctgca cgaggcgggg gtattcggct tcaaggcgtt
    24421 cctgtcgccg tccggcgtcg acgagttccc tcacctcgac caggaacagc tcgcccgcgc
    24481 cctgcgcgag atcgcctcct tcgacggcct gctcatcgtc cacgccgagg acccgggcca
    24541 cctcgccgac gccccgcagc ggggcggccc ccgctacgcc gacttcctcg cctcccggcc
    24601 ccgccgggca gaggacaccg ccatcgcgca gctcctggag caggcccggc gcttcgacgc
    24661 gcgcgtgcac gtgctgcacc tctcctcggc cgacgcgctg cccctgatcg ccgaggccaa
    24721 ggcggacggc gtccgcgtca ccgccgagac ctgcccgcac tacctcaccc tcaccgcgga
    24781 ggaagtcccg gacggcgcga gcgagttcaa gtgctgcccg cccatccgcg aggccgccaa
    24841 ccaggacctg ctgtggcagg ccctggccga cggcaccgtc gactgcgtcg tcaccgacca
    24901 ctccccgtcc accgccgacc tcaagacgga cgacttcgcc accgcctggg gcggcatctc
    24961 cggcctccag ctcagcctcc cggccgtctg gaccgaggcc cgcaggcgcg gccacgccct
    25021 ggaggacgtg gtccgctgga cggcgacgcg cacggcccgg ctggccggcc tcggggcccg
    25081 caagggcgcc atcgcgcccg gccgcgacgc cgacttcgcc gtcctcgccc ccgacgagac
    25141 cttcaccgtc gacccggccg ccctccagca ccgcaaccgc gtgaccgcct acgccggacg
    25201 caccctgcac ggcgtcgtga ggtccacctg gctgcgcggc gaacgcgtcc tgtccgacgg
    25261 ggagttcacc gcaccgaagg gccgcctgct cacccggccc tgaaacgaca tccgaaaggc
    25321 aggaccacat caccgtgacg gcgatcgaga ccttcaccgg cgacgccagc ccctacggcg
    25381 gcggcgaccc gtacgcggac taccgcaccg ccgacttccc cttcacccac ctcgccgacc
    25441 tcgccgaccg ccggctcggc gccggtgtca tcgccgccaa tgacgagttc ttcgccgagc
    25501 gcgagaacct cctgctgccc ggccgccccg tcttcgaccc ggaacgcttc ggccacaagg
    25561 gcaagatcat ggacggctgg gagacccggc ggcggcgcgg cgtctccgcc gaccacccct
    25621 ggcccgccga ggacgaccac gactgggcgc tgatccgcct cggcacgccc ggcgtcgtcc
    25681 gcggcgtcgt cgtcgacacc gcccacttcc gcggcaacta cccgcaggcg gtctcggtgg
    25741 agggcaccgc cgtcgacggc tccccgtcgc ccgaggaact gctctccgac gaagtgaagt
    25801 ggacgacgct ggtgccgcgc acccggatcg gcggccacgc ggccaacggc ttcgccgtca
    25861 ccgccgaaca gcgcttcacc cacctgcgcc tcaaccagca ccccgacggc ggcatcgccc
    25921 gcctccgcgt gtacggcgag gtcgtccccg acctggcctg gctcaccgcg ctcggcacct
    25981 tcgacgtcgt cgccctggag aacggcggcc gtgtcgagga cgcctccgac cgcttctact
    26041 cgcccgccgc caacaccgtc cggcccggcc gctcccggaa gatggacgac ggctgggaga
    26101 cccggcggcg ccgcgaccac ggccacgact ggatcacgta ccgcctggtc gcccggtcgc
    26161 agctccgcgc gctggagatc gacaccgcct acctcaaggg caacgcggcc ggctgggcgt
    26221 cggtgtccgt gcgggacggt gaggacggcg actggcggga gatcctgccc cgcacccgcc
    26281 tccagcccga caccaaccac cgcttcgtcc tcccggaccc cgcggtgggc acccacgcgc
    26341 gcgtggacat ccaccccgac ggcggcatct cccgcctccg cctcttcggc accctgacgg
    26401 accgggggac ggcggcactg gaggcacgga ggcaggagct cgggggctga ctcccgcgcg
    26461 ggcgcccgcc tttcggaacc cgcctccgga agcgggcgcc cccacggtcc gttcaggccg
    26521 cgtgaccgcc gtccaccgcc acctccgcgc ccgtcacgta cgcggcgtcc gcgaggtgga
    26581 cgatggtctc cgccacctcc tccgccgtac cgaaccggcc cagggcggtg gccgccgcct
    26641 gaccggccgc gtaggggccg ccggccgggt tcatctccgt gtcggtcggc cccggatgga
    26701 cgatgttcgc ggtgatcccg cgctcgccca gctcccgcgc cagcgccttg gtgagcccca
    26761 ccagcgccgc cttgctcatc gcgtagaggg tcccgcccgg gcccgtcacc cgctgcgtca
    26821 tgcacgagcc gacggtgacg atccggcccc cgcgcgccat caccgcggcc gccgcgcgcg
    26881 aggtgaggaa gacaccgcgc acgttcaccg cgagcacccg gtcgacgtcg gcgggggaga
    26941 gggactccag cgggccgagc acgccgacgc ccgcgttgtt caccagcacg tccagccggc
    27001 ccagttcccg cacggccgtg gtcaccgccg aggccgcttc ctccgggtcg ccggcgtccg
    27061 cgcgcagggc caccgcgcgg cgccccagcg cctcgacggc ccgtacgacg tcctccgccg
    27121 cctcctttcc gctcacgtac gtcaccgcga cgtccgcgcc ctcccgggcg agccgcagtg
    27181 ccgtcgcggc gccgatgccg cggctgccgc cggtcaccag cgccgcccgg ccgagcaggg
    27241 tcttctccgt gatctgtgtg gtcatacgtc catctcagcg gccgacgcgg gagggcaccg
    27301 gcggcgatcg gacgtcgacc tgccgctccg tcacccggtc cggcacgccc ccgtgccacg
    27361 tcaccgaaaa ctcatcggac cacaccgaaa catccatgta cttgacattg acatgccagt
    27421 gtctacgcgc gtcatcatgg ggtatgcgat tccccccacg agcggcccgg tccggggccg
    27481 cggcatccct cctgtccgcc ctcctgctgg gcggcggcgg agcgctctcc gccccggcgg
    27541 cacacgccgc ccccgccctt cctgtcgccg tgtccgccac gccgtccgtc ctggcggtcg
    27601 gcgacatctg ctacggcgac ctgccgtccg aggcgcacga caccctcgac ctcgtcgaac
    27661 agggcggccc gttccccttc gagcaggacg gcactgtctt ccagaacagg gagggcatcc
    27721 tccccggcca ggacaccggc tactaccacg agtacacggt gatcacgccc ggttccccca
    27781 cccgcggcgc ccgccggatc gtgaccggtg aggagtacca cgaggactac tacaccgccg
    27841 accactacgc ctcgttcgac ctggtcgacc actcctgctg accggttcct ggccggccgg
    27901 cggctcagcc gcctggcttc cgggtctccg cgagggcgaa cagagcgacg cccagcacca
    27961 gcagggcgac gctcgcgtag atctcgtagc ctgcgaggaa cccggcccgc cgcaccaggc
    28021 cccagttcca gtcggtgaac tccgtcacca gaccggccac gccctgaagc acggccagga
    28081 accccacgat ctccagcagc ttcttcatgc ccccgactct cgccccgcgg accccccacc
    28141 cacatcggcc gcggggcgag gccttcccga ccgaggtgga cggcctgctt ccgccgggac
    28201 gccgaaagtc tgaggccgcg cgactttggt cggcgattcc gcccgcgagg cgccgtaccg
    28261 ggcgcccact gcatagattt gtcgaccgtg accgatgaca aggcggcgag gaccgccccc
    28321 gcgtacacgg ggcccagttg gttcttcccg tccgccctca tccacgagct cgaccccgac
    28381 gcgagccgct ccggccgccg tccccggcga accgcccgcg actgggtcgt cgacttctcc
    28441 tgcttcctgc tcgcggtgct gatcggactg ctcggcgccg aagcactgcg ggacaacacc
    28501 gacctcccgc acgccgtcgc cgtcctcgac caggtgctcg gcgcgctctc ctgcgcggcg
    28561 gtctggctgc gccgccggtg gccgttcggc ctggccgtgg ccatggtgcc ggtcggcttc
    28621 ctctccgaga cctccggcgg cgtcgcgatc atcgccctgt tcacgctcgc cgtgcaccgg
    28681 ccgttccggt acgtggcctg ggtggccggc gcgcagctgg cgctcacgcc gctgtacttc
    28741 tggtggcgcc ccgaccccga cctgccgtac ctcgccgtcg tcgtccttct cctcgtgctg
    28801 accgtcgcca cggtcggctg gggcatgttc gtccggtcca aacggcagct catgctcagc
    28861 ctgcgggacc gggcccggcg cgccgagacg gaggcgcggc tgcgggccga acaggcgcag
    28921 cggctcgccc gcgaggccat cgcgcgggag atgcacgacg tgctcgcgca ccggctgacg
    28981 ctgctcagcg tgcacgcggg cgcgctggag ttccggcccg acgccccgcg cgacgagatc
    29041 gcgcgggcgg ccggcgtgat ccgggagagc gcccacgagg cactccagga cctgcgggag
    29101 atcatcgggg tgctgcgggc cggcgacagc gaggacgcgg ggcgtccgca gccgacgctg
    29161 gcggcgctcg acacccttgt cgccgagtcc cgccaggcgg gcatgaaggt caccctggac
    29221 cagcgggtca cccacaccgc ctccgtcccc gcctccgtcg gccgcaccgc ctaccgcatc
    29281 gcccaggagg gcctgaccaa cgcccgcaaa cacgcccccg gcacggaggt cacggtctcc
    29341 gtctccggcg gcccgggcga ggacctcacc gtgcgggtcc acaacccgcc cccggagggg
    29401 gacgtccccc cggttcccgg cgcgggccag ggcctgatcg gcctgacgga acgggcgacg
    29461 ctggctgggg gttccctggc gcacggccgg accccggagg gcggcttcga ggtgagggca
    29521 cggctgccgt ggcgctagac gtggtcccca ccacggcacc tctgcaccgc acctcggctg
    29581 cacgccgtac ctgcggctcg gggggtgctt cgccatgtcg ttcgcgccgg gtgcgggccg
    29641 tgggggggct ggtcgcgccg ttccccgcgc ccctcggggc gcccgcaagc gacgagttgc
    29701 gcggacaccc tcgggtcgcg acaccccggt gcatgattac gtaccgccca tgacaagaat
    29761 ccgcgtgctc ctcgtggacg acgaccccct cgtccgcgcc ggcctctcct tcatgctggg
    29821 cggcgccgac gacatcgaga tcgtcggaga ggccgccgac ggcgccgagg tcagcgcact
    29881 cgtcgaccgc acccacccgg acgtcgtcct catggacatc cgcatgccct ccgtcgacgg
    29941 cctcaccgcc accgagacgc tgcgcggccg cgacgatgcc ccgcagatcg tcgtgctcac
    30001 caccttccac gccgacgacc aggtcctgcg cgcactccgc gcgggcgcgg ccggcttcgt
    30061 gctgaaggac accccgcccg ccgagatcgt cgccgccgta cgccgcgtcg cggccggcga
    30121 cccggtgctg tcgcccgcgg tcacccggca gctgatggcc cacgccgccg gcgacccggg
    30181 accgggcgac ggccgccgtt cccgcgcccg cgaccgcgtc gccgccctaa acgaccgcga
    30241 acgcgaggtc gccgtggccg tcggccgggg cctcgccaac gcggagatcg ccgccgcgct
    30301 gtacatgagc gtggccacgg tcaagacgca cgtctcccgc atcctggcca agctcgacct
    30361 caacaaccgt gtccagatcg cgctgctcgc ccatgacgcg ggcctgctgg aggagaccga
    30421 cagcccgtga cgtccaccgg ccgttccgag gagccccgca ccgtgacccc gccgcccgaa
    30481 ctcgacctcg ccgccgcacg gaagctgctg gacgcccagc cgttcagcag gctcctcggc
    30541 gcccgtgtca ccgccttcgg cgacggcggg gccaccctgg agatcgacat ccgggaggac
    30601 ctgcaccagc agaacggctt cctgcacggc ggcgtcctcg cctacgccgc cgacaacgcg
    30661 ctcaccttcg ccgccggcgc ggtcctcgga ccgtcggtgc tgaccggcgg cttctccgtc
    30721 cagtacctgc gtccggccac cggccgcacc ctccgcgccc gcgccaccgt cgtccacgcg
    30781 ggcagacgcc aggcggtcac ccgctgcgac ctcctcacgg tgacggagga cgacgaggag
    30841 accctgtgcg cggtggcgca ggggacggtc ctcccggtga cggcccgccc ttcatgaggg
    30901 cacgagaagc acgacgacat gaaggagggg gtgtcgcccg acacccccgt gtctcacgtc
    30961 agcgcctcct gcgcgctgct cagcagctcc gccggccgca ccggtctgcg ctcccgccgc
    31021 gatctctcgc acgcctccgc gatcagcagc gcccgcaggg cctcatggcc gtcgcacggg
    31081 ttgggccgct cgccccgcac cacctcgacg aacgcgacca gttccgcctc gtacgcgggt
    31141 ccgaaccgct ccaggaagcc ggtccacggc ttgtccgcgg cgggcggtcc cgtcggctcg
    31201 gtggacgcga tgggcgtacg gtcgtcgaga ccgacgacga
//
