LOCUS       NZ_BMSZ01000046         3222 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces badius strain JCM 4350 sequence46, whole genome shotgun
            sequence.
ACCESSION   NZ_BMSZ01000046
VERSION     NZ_BMSZ01000046.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces badius
  ORGANISM  Streptomyces badius
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 3222)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: BGI assembly pipeline
            Genome Coverage                   :: 154X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014649415.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 03:57:07
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,894
            CDSs (total)                      :: 6,825
            Genes (coding)                    :: 6,582
            CDSs (with protein)               :: 6,582
            Genes (RNA)                       :: 69
            rRNAs                             :: 2 (23S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 244
            CDSs (without protein)            :: 243
            Pseudo Genes (ambiguous residues) :: 0 of 244
            Pseudo Genes (frameshifted)       :: 70 of 244
            Pseudo Genes (incomplete)         :: 206 of 244
            Pseudo Genes (internal stop)      :: 7 of 244
            Pseudo Genes (multiple problems)  :: 38 of 244
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:11:55
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 3222
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMSZ01000046.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..3222
                     /culture_collection="JCM:4350"
                     /db_xref="taxon:1941"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces badius"
                     /strain="JCM 4350"
                     /submitter_seqid="sequence46"
                     /type_material="type strain of Streptomyces badius"
     gene            complement(<1..>3222)
                     /locus_tag="IE135_RS33400"
     region          1..3222
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..3222
                     /SMILES="NCC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..3222
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<0:3222](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<1..3222)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     CDS             complement(<1..3222)
                     /NRPS_PKS="Domain: AMP-binding (87-482). E-value: 9.4e-116.
                     Score: 378.7. Matches aSDomain:
                     nrpspksdomains_IE135_RS33400_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (591-660). E-value: 2.4e-27. Score:
                     86.9. Matches aSDomain: nrpspksdomains_IE135_RS33400_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (674-975). E-value:
                     4.9e-114. Score: 372.3. Matches aSDomain:
                     nrpspksdomains_IE135_RS33400_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011028843.1"
                     /locus_tag="IE135_RS33400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_199889938.1"
                     /sec_met_domain="AMP-binding (E-value: 7.6e-124, bitscore:
                     399.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7.1e-17, bitscore:
                     48.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 2.3e-72, bitscore:
                     229.7, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFGERRDEAGEPDGLDGRLEFASDLFDTETAERLVQRLLHVLAQ
                     VTEAPDRRLAEIDLLDDAERRQTLTAWNDTGAPVPDAPLDALFAAQAVRTPDAPAVTAG
                     AETLTYSQLDARANRLAHHLKVRGAGPGRYVGLLLPRTADLLVGLLAVLKTGAAYLPID
                     PDYPTERIGHMVEDADPALLVTVSALEPVLPTGENAAGQTGGRVLLDRADLAAEPTGAP
                     ESGHSAAHPAYVIFTSGSTGRPKGVVIGHRALVNFLTSMQQRFGLTAKDRLLAVTTTGF
                     DIAGLELFLPLLHGATVVLADRDDVRDSAALRRLVTDSGTTILQATPGLWRSLLAEEPQ
                     LSAVRALVGGEALPADLAEALVARTAGVTNLYGPTETTIWSTAFEVTAGAPVRIGRPIA
                     NTRAYVLDARLAPVPPGVAGELYLAGDGIAAGYLGRPDLTAERFTADPFHPGARMYRTG
                     DLARWTRDGELAYLGRVDHQVKIRGYRIELGEIESVLTAHPDVRSAAVLVREDRPGDRR
                     IAAYVVAGPGADPAATVAELRRHVGASLPVYMVPATVTLLGALPQTPNGKLDRRALPAP
                     EYGTAAVPAAPRSPREEILCCLFAEVLDVPAVGIDDGFFDLGGHSLLATRLAGRVRAVL
                     GVELPVRQLFDTPTVAGLSVALERAERARPAVVAAVPRPDRLPMSFAQRRLWFLHQLEG
                     PGATYNIPAVLRLTGDLDEAALRLALGDVMARHESLRTVFCEDADGPYQLVVEPEICEP
                     GLSVVTTSPEDLPERLRTATRYGFDLANESPLRSWLFRLGGQEHVLLVLLHHIAADGWS
                     LPLLARDLMAAYTARARGAAPDWEPLPVQYADYSIWQREVLGSEDAPDSLSAQQLAFWQ
                     RTLAGLPDELVLPTDRPRPVSASHRGDAARFRITAAQHERLIALAREHDVSLFMVVQAA
                     VATVLTRLGAGTDIPLGSTVAGRGDPALEDLVGFFVNTLVLRTDTSGDPTFAELLGRVR
                     EVDLAAYAHQDVSFEQLVEKLNPVRSLNRHPLVQTIISFNNTGNEAAVGDFEDLPGLRV
                     SRYETDTVAVKFDLLFRFVERFGADG"
     CDS_motif       complement(151..258)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE135_RS33400_0011"
                     /evalue="6.10E-17"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="IE135_RS33400"
                     /protein_end="1024"
                     /protein_start="988"
                     /score="54.0"
                     /tool="antismash"
                     /translation="REVDLAAYAHQDVSFEQLVEKLNPVRSLNRHPLVQT"
     aSDomain        complement(298..1200)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE135_RS33400_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="4.90E-114"
                     /label="IE135_RS33400_Condensation_LCL.1"
                     /locus_tag="IE135_RS33400"
                     /protein_end="975"
                     /protein_start="674"
                     /score="372.3"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIAADG"
                     /tool="antismash"
                     /translation="DRLPMSFAQRRLWFLHQLEGPGATYNIPAVLRLTGDLDEAALRLA
                     LGDVMARHESLRTVFCEDADGPYQLVVEPEICEPGLSVVTTSPEDLPERLRTATRYGFD
                     LANESPLRSWLFRLGGQEHVLLVLLHHIAADGWSLPLLARDLMAAYTARARGAAPDWEP
                     LPVQYADYSIWQREVLGSEDAPDSLSAQQLAFWQRTLAGLPDELVLPTDRPRPVSASHR
                     GDAARFRITAAQHERLIALAREHDVSLFMVVQAAVATVLTRLGAGTDIPLGSTVAGRGD
                     PALEDLVGFFVNTLVLRTDT"
     CDS_motif       complement(307..396)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE135_RS33400_0010"
                     /evalue="2.30E-15"
                     /label="C5_LCL_267-296"
                     /locus_tag="IE135_RS33400"
                     /protein_end="972"
                     /protein_start="942"
                     /score="48.9"
                     /tool="antismash"
                     /translation="DIPLGSTVAGRGDPALEDLVGFFVNTLVLR"
     CDS_motif       complement(664..702)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE135_RS33400_0009"
                     /evalue="5.50E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="IE135_RS33400"
                     /protein_end="853"
                     /protein_start="840"
                     /score="18.8"
                     /tool="antismash"
                     /translation="QYADYSIWQREVL"
     CDS_motif       complement(751..816)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE135_RS33400_0008"
                     /evalue="4.50E-11"
                     /label="C3_LCL_132-143"
                     /locus_tag="IE135_RS33400"
                     /protein_end="824"
                     /protein_start="802"
                     /score="35.2"
                     /tool="antismash"
                     /translation="LHHIAADGWSLPLLARDLMAAY"
     CDS_motif       complement(1021..1134)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE135_RS33400_0007"
                     /evalue="8.10E-19"
                     /label="C2_LCL_024-062"
                     /locus_tag="IE135_RS33400"
                     /protein_end="734"
                     /protein_start="696"
                     /score="60.0"
                     /tool="antismash"
                     /translation="ATYNIPAVLRLTGDLDEAALRLALGDVMARHESLRTVF"
     CDS_motif       complement(1153..1185)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE135_RS33400_0006"
                     /evalue="2.70E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="IE135_RS33400"
                     /protein_end="690"
                     /protein_start="679"
                     /score="10.3"
                     /tool="antismash"
                     /translation="SFAQRRLWFLH"
     aSDomain        complement(1243..1449)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE135_RS33400_PCP.1"
                     /evalue="2.40E-27"
                     /label="IE135_RS33400_PCP.1"
                     /locus_tag="IE135_RS33400"
                     /protein_end="660"
                     /protein_start="591"
                     /score="86.9"
                     /tool="antismash"
                     /translation="EEILCCLFAEVLDVPAVGIDDGFFDLGGHSLLATRLAGRVRAVLG
                     VELPVRQLFDTPTVAGLSVALERA"
     aSModule        complement(1243..2961)
                     /complete
                     /domains="nrpspksdomains_IE135_RS33400_AMP-binding.1"
                     /domains="nrpspksdomains_IE135_RS33400_PCP.1"
                     /locus_tags="IE135_RS33400"
                     /monomer_pairings="Gly -> Gly"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(1747..1812)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE135_RS33400_0005"
                     /evalue="8.60E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="IE135_RS33400"
                     /protein_end="492"
                     /protein_start="470"
                     /score="40.1"
                     /tool="antismash"
                     /translation="YLGRVDHQVKIRGYRIELGEIE"
     aSDomain        complement(1777..2961)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE135_RS33400_AMP-binding.1"
                     /evalue="9.40E-116"
                     /label="IE135_RS33400_AMP-binding.1"
                     /locus_tag="IE135_RS33400"
                     /protein_end="482"
                     /protein_start="87"
                     /score="378.7"
                     /specificity="substrate consensus: Gly"
                     /tool="antismash"
                     /translation="FAAQAVRTPDAPAVTAGAETLTYSQLDARANRLAHHLKVRGAGPG
                     RYVGLLLPRTADLLVGLLAVLKTGAAYLPIDPDYPTERIGHMVEDADPALLVTVSALEP
                     VLPTGENAAGQTGGRVLLDRADLAAEPTGAPESGHSAAHPAYVIFTSGSTGRPKGVVIG
                     HRALVNFLTSMQQRFGLTAKDRLLAVTTTGFDIAGLELFLPLLHGATVVLADRDDVRDS
                     AALRRLVTDSGTTILQATPGLWRSLLAEEPQLSAVRALVGGEALPADLAEALVARTAGV
                     TNLYGPTETTIWSTAFEVTAGAPVRIGRPIANTRAYVLDARLAPVPPGVAGELYLAGDG
                     IAAGYLGRPDLTAERFTADPFHPGARMYRTGDLARWTRDGELAYLGRVDHQVKIR"
     CDS_motif       complement(1828..1848)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE135_RS33400_0004"
                     /evalue="3.70E+01"
                     /label="C4_LCL_164-176"
                     /locus_tag="IE135_RS33400"
                     /protein_end="465"
                     /protein_start="458"
                     /score="-2.1"
                     /tool="antismash"
                     /translation="DLARWTR"
     CDS_motif       complement(1894..1983)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE135_RS33400_0003"
                     /evalue="1.80E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="IE135_RS33400"
                     /protein_end="443"
                     /protein_start="413"
                     /score="52.1"
                     /tool="antismash"
                     /translation="PPGVAGELYLAGDGIAAGYLGRPDLTAERF"
     CDS_motif       complement(2470..2529)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE135_RS33400_0002"
                     /evalue="2.50E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="IE135_RS33400"
                     /protein_end="251"
                     /protein_start="231"
                     /score="32.2"
                     /tool="antismash"
                     /translation="AYVIFTSGSTGRPKGVVIGH"
     CDS_motif       complement(2734..2775)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE135_RS33400_0001"
                     /evalue="2.70E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="IE135_RS33400"
                     /protein_end="163"
                     /protein_start="149"
                     /score="17.3"
                     /tool="antismash"
                     /translation="LAVLKTGAAYLPID"
ORIGIN
        1 cccatccgca ccgaaccgct ccacgaaccg gaacagcaga tcgaacttga ccgcgacggt
       61 gtccgtctcg taccggctca cccggagacc gggaaggtcc tcgaagtcgc cgaccgcggc
      121 ctcgttcccg gtgttgttga agctgatgat ggtctggacg agcgggtgcc ggttgagcga
      181 gcggaccggg ttgagcttct ccaccagttg ttcgaacgac acgtcctgat gggcataggc
      241 cgcgaggtcc acttcccgta ctcggcccag cagttcggcg aacgtcggat cgcccgaggt
      301 gtcggtccgc agcaccaggg tgttgacgaa gaagccgacg aggtcctcca gggccggatc
      361 gccgcgcccc gcgaccgtgc tgccgagggg gatgtccgtg ccggcgccga gccgggtgag
      421 gaccgtcgcg acagcggcct gcaccaccat gaagaggctg acgtcgtgct cgcgggccag
      481 cgcgatcagc cgttcgtgct gcgcggcggt gatccggaag cgggcggcgt cgccccggtg
      541 cgaggcggac acgggacgcg gccggtcggt cgggagcacc agttcgtcgg ggagcccggc
      601 cagggtccgc tgccagaaag ccagttgttg ggcggagagg ctgtccgggg cgtcttcgga
      661 gcccagtacc tcacgctgcc agatgctgta gtcggcgtac tggaccggca gcggttccca
      721 gtcgggggcc gcgccccggg cgcgggcggt gtaggcggcc atcaggtcgc gggcgagcag
      781 gggcagcgac cagccgtcgg cggctatgtg gtggagcagt acgagcagca cgtgctcctg
      841 gccaccgagc cggaagagcc agctgcgcag cgggctctcg ttggcgaggt cgaagccgta
      901 ccgggtggct gtgcgcagcc gctccggcag gtcctcgggc gaggtggtga cgacggagag
      961 gcccggctcg cagatctccg gttccaccac gagctggtag ggcccgtcgg cgtcctcgca
     1021 gaagaccgtc cgcaggcttt cgtggcgagc catcacatcg cccagcgcca ggcggagtgc
     1081 ggcctcgtcg aggtcgccgg tgagccgcag cacggcggga atgttgtacg tggcgccggg
     1141 gccctccagc tggtggagga accacagacg ccgctgggcg aaggacatcg gcagtcggtc
     1201 ggggcgcggt acggcggcga cgacggcggg ccgcgcccgc tcggcgcgct ccagcgcgac
     1261 ggacagcccc gcgacggtcg gcgtgtcgaa gagctggcgg accggcagct ccacaccgag
     1321 caccgcgcgc acccgcccgg ccagccgggt cgccagcagc gagtggccgc ccaggtcgaa
     1381 gaagccgtcg tcgatgccga cagccggtac gtccagcacc tccgcgaaga ggcagcagag
     1441 gatctcctcc cgcggggagc ggggtgcggc cgggacggcg gccgtgccgt actcgggggc
     1501 gggcagcgcg cgccggtcga gcttgccatt gggcgtctgc gggagcgcgc ccagcagggt
     1561 cacggtggcg ggcaccatgt agacgggcag cgacgcgccg acgtgccggc gcagctcggc
     1621 cacggtggcg gccgggtccg cgccggggcc ggccaccacg tacgcggcga tgcgacggtc
     1681 gccgggccgg tcctcgcgca ccagcacggc ggcgctccgc acgtcggggt gggcggtcag
     1741 cacggactcg atctcgccca gttcgatgcg gtagccgcgg atcttgacct ggtggtcgac
     1801 ccttccgagg taggcgagtt cgccgtcccg cgtccagcgg gcgaggtcgc cggtccggta
     1861 catccgcgcg ccggggtgga acgggtcggc cgtgaagcgc tcggcggtca ggtcggggcg
     1921 gcccaggtag ccggccgcga tgccgtcccc cgccaggtac agctcgccgg cgacgcccgg
     1981 gggcaccggg gcgaggcggg cgtccaggac gtacgccctg gtgttggcga tcgggcggcc
     2041 gatgcgcacg ggcgcaccgg cggtgacctc aaaggcggtg gaccagatgg tggtctcggt
     2101 ggggccgtag aggttggtca cgccggccgt acgtgccacg agggcctcgg cgagatcggc
     2161 gggcagcgcc tcgccgccga cgagggcgcg caccgcggac agctggggtt cctccgcgag
     2221 cagcgaacgc cagagtcctg gggtcgcctg gaggatcgtc gtcccgctgt ccgtgacgag
     2281 tcgccgcagc gccgcggagt cgcgtacgtc gtcccggtcg gccaggacca cggtggcacc
     2341 gtggagcagg ggcaggaaga gttcgagccc ggcgatgtcg aatccggtgg tcgtgacggc
     2401 gagcagccgg tccttcgccg tgaggccgaa gcgctgctgc atggaggtga ggaagttgac
     2461 cagggcccgg tggccgatca cgacgccctt gggccgcccg gtggaaccgg aggtgaagat
     2521 cacgtacgcg ggatgggccg cgctgtgccc gctctcgggg gcgccggtgg gctcggcggc
     2581 gaggtcggcg cggtcgagca gcacccgccc gccggtctgg ccggcggcgt tctcgcccgt
     2641 cggcaggacg ggctccagcg cgctcaccgt gacgaggagt gcggggtccg cgtcctcgac
     2701 catgtggccg atgcgctcgg tgggatagtc ggggtcgatc ggcaggtatg cggcgccggt
     2761 cttcagtacc gcgagcagcc ccacgagcag gtcggcggtg cggggcagca gcaggccgac
     2821 gtacctgccg gggcctgcgc cccggacttt gaggtggtgg gccagccggt tggcacgcgc
     2881 gtcgagttgg gagtacgtga gggtctcggc gcccgccgtg accgcggggg cgtccggcgt
     2941 gcggacggcc tgggcggcga agagcgcgtc gagcggggcg tccgggaccg gggccccggt
     3001 gtcgttccag gcggtgaggg tctgccgtcg ctcggcgtcg tccagcaggt cgatctcggc
     3061 gagccgccgg tcgggggcct cggtcacctg cgccaggacg tgcagcagcc gctgcacgag
     3121 tcgctcggcg gtctccgtgt cgaagaggtc ggaggcgaac tccagccggc cgtccagtcc
     3181 gtcgggttct cccgcctcgt cgcgccgttc accgaacccg aa
//
