LOCUS       NZ_BMSZ01000030        21614 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces badius strain JCM 4350 sequence30, whole genome shotgun
            sequence.
ACCESSION   NZ_BMSZ01000030
VERSION     NZ_BMSZ01000030.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces badius
  ORGANISM  Streptomyces badius
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 53170)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: BGI assembly pipeline
            Genome Coverage                   :: 154X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014649415.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 03:57:07
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,894
            CDSs (total)                      :: 6,825
            Genes (coding)                    :: 6,582
            CDSs (with protein)               :: 6,582
            Genes (RNA)                       :: 69
            rRNAs                             :: 2 (23S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 244
            CDSs (without protein)            :: 243
            Pseudo Genes (ambiguous residues) :: 0 of 244
            Pseudo Genes (frameshifted)       :: 70 of 244
            Pseudo Genes (incomplete)         :: 206 of 244
            Pseudo Genes (internal stop)      :: 7 of 244
            Pseudo Genes (multiple problems)  :: 38 of 244
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:11:55
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 21614
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMSZ01000030.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21614
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lassopeptide"
                     /region_number="1"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..21614
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21614
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[8868:11614](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(8869..11614)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            <1..375
                     /locus_tag="IE135_RS32415"
                     /pseudo=""
     CDS             <1..375
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006126501.1"
                     /locus_tag="IE135_RS32415"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="MarR family transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="LAAQWLDRGVTTDYLTSTLTAGLPAQVDSPVGLLRRRLTDKLPPR
                     IPATPSTPPNTPDPTATRRLLVECTDCGRPGQPEALPDGLCHPCHRTHTAHDDTTPPDP
                     TQIAAVKAHMANLRHLLKPV"
     gene            396..1382
                     /locus_tag="IE135_RS32420"
                     /old_locus_tag="GCM10010253_65680"
     CDS             396..1382
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007388482.1"
                     /locus_tag="IE135_RS32420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_65680"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_234428182.1"
                     /transl_table=11
                     /translation="MADQSVAAGVSLAGVMAHCGGSPVGAVELLVGAIASAPTAPEPYA
                     ALAALWQGLRPDGLRESLAEDGSLSTVPAQAYFLFLEGDMDNAVMALGSVTGVRPDVAW
                     GAAPWFGDARFLGAVSAAALAEACLRTLDYGRDLDTDAMRERFAPWFHALDVVSERDPA
                     PESLAAMARLPRACGRYELSFALCDRADAVDPVMWTALARAATWRAMGNLDQAAASFER
                     ALLLEPGNWSLYLDLADLRAEQGDFAAAASIVEQGLQHEPREATLRAASAAYRTRLVGS
                     ADDLTALIALAPSLADTAYRNLLIDYACAGPQLPPGLVAEAHRIQES"
     gene            complement(1669..>1920)
                     /locus_tag="IE135_RS32425"
                     /old_locus_tag="GCM10010253_65700"
                     /pseudo=""
     CDS             complement(1669..>1920)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010071624.1"
                     /locus_tag="IE135_RS32425"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_65700"
                     /product="GNAT family N-acetyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="VRTRRTGTDLHVGRLAVAPDLRGQGVGRWLLRLAESAGEGCGRIV
                     LSTGAASHRNIALYQQQGYALLPETQEAGAVDLAKAVA"
     misc_feature    2048..2061
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.15"
                     /tool="antismash"
     misc_feature    2064..2080
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.76"
                     /tool="antismash"
     gene            2079..2543
                     /locus_tag="IE135_RS32430"
                     /old_locus_tag="GCM10010253_65710"
     CDS             2079..2543
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006126496.1"
                     /locus_tag="IE135_RS32430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_65710"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_069735445.1"
                     /transl_table=11
                     /translation="MSTNETAPPVDWLTPDEDRAWRAYLRMVTAVQVGVAQDLAALGLS
                     EPDYEVLSTLSEREDGTSTLHEQAAKMGWSRSRLSRHASRMEARGLIRRAPDPTDGRGC
                     LLVLTSAGWDVLRDAAPSHVTSVRRHFVDRLTPEELATLGRIAGKLSADR"
     gene            complement(2580..3026)
                     /locus_tag="IE135_RS32435"
                     /old_locus_tag="GCM10010253_65720"
     CDS             complement(2580..3026)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005482038.1"
                     /locus_tag="IE135_RS32435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_65720"
                     /product="anthrone oxygenase family protein"
                     /protein_id="WP_069735446.1"
                     /transl_table=11
                     /translation="MLDVLEVVTTVIVGLLVGVEFSVAFVINRILDALPDDSAQRGRSH
                     GGRMLGAVMPFWYIGSLVLSAIWAVAGWGEPGAGLVVAAGALLLLGVLMSLLLLVPIND
                     RGKTWTSENRPEDWKEQMNRWDRYHYARVAVLIGAFASLVAALA"
     gene            3118..3696
                     /locus_tag="IE135_RS32440"
                     /old_locus_tag="GCM10010253_65730"
     CDS             3118..3696
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981641.1"
                     /locus_tag="IE135_RS32440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_65730"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_069735447.1"
                     /transl_table=11
                     /translation="MSVQERKERERANRERLIVATARELADQQGWDAVTTRRLAERIEY
                     SQPVLYSHFRGKREIIGAVALEGATEMASALRAASSGADGRRTRVAALAHAYLEFAERN
                     PAVYDALFQLDGGLAFAREDTPEPLKDAFAALLETLGEVAGEGVHPALFTELFWSALHG
                     LATLTRAGRLLPEGAGERLDLLVERLAVL"
     gene            complement(3828..5051)
                     /locus_tag="IE135_RS32445"
                     /old_locus_tag="GCM10010253_65740"
     CDS             complement(3828..5051)
                     /GO_function="GO:0000009 - alpha-1,6-mannosyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004376 - glycolipid mannosyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006506 - GPI anchor biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003967341.1"
                     /locus_tag="IE135_RS32445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_65740"
                     /product="mannosyltransferase family protein"
                     /protein_id="WP_199889816.1"
                     /transl_table=11
                     /translation="MSTLSPGLRPSPVRPAPEPRSAEPRLARFRLAPADRGILWLYLLT
                     RVSLWITAHFARWLFPAQSGVREAAPVLAPFQQWDANHYLHIARDGYFPAGAGPWTSGW
                     DNREAFFPGYPLLLRAVHTVVPHWTAAGLLISFIAGAVAVLALARLARAYLPEDAAGPR
                     TAVLFLLSPCAVFLAAGYTEALFLAFALPAWLVAMKHRWALAAVLTTSATAVRVSGLFL
                     AAAVGLLFLLSVRAGEGRRRWRAAGWTLLPALPPAAYSWYLHARTGDWVAWKHAQERGW
                     YRTFHAPWEAWANTWTGAFGGTQSTGYAFMFQAELAAMVVGLALVVLLVRRRRWPEAVY
                     VALSLWALGTSYWYTSVPRATLLWWPLWIGLAALSLRRPWFRTAYLCVAAPVTTLVALT
                     FLTGRWAG"
     gene            complement(5172..5648)
                     /locus_tag="IE135_RS32450"
                     /old_locus_tag="GCM10010253_65750"
     CDS             complement(5172..5648)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006126494.1"
                     /locus_tag="IE135_RS32450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_65750"
                     /product="hypothetical protein"
                     /protein_id="WP_069735448.1"
                     /transl_table=11
                     /translation="MSEPRDPKEPQDPLRSLFREAGEFGQALTAPDTASSITRRGMRAQ
                     RRRMAVVAVGVCLVVGGGGAVAVGLLPVRPQPVAPATNPSPSYPSPVPSEGLPTEQPST
                     PPSPSTTVPGSAGTRGAEGPSGRTTEPGGPPTRTRTSTTPPTASATTDGGASTP"
     gene            complement(5641..6141)
                     /locus_tag="IE135_RS32455"
                     /old_locus_tag="GCM10010253_65760"
     CDS             complement(5641..6141)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018489040.1"
                     /locus_tag="IE135_RS32455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_65760"
                     /product="SigE family RNA polymerase sigma factor"
                     /protein_id="WP_065487879.1"
                     /transl_table=11
                     /translation="MTVEEFEEFYAQAVARLTGQLYVMTGDLQEAQDVVQEAFVKAWVR
                     RGRLERDGQPEAWIRTVAWRLAVSRWRFRRRSADAWGRGSGGAEHVAPPDPDHVVLVDA
                     LRELPAQQRRTLTLHYLCDLTVEQIAGETGLSTSTIKTHLVRGRAALAHRLRDPRIEEA
                     PDV"
     misc_feature    6113..6126
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.98"
                     /tool="antismash"
     misc_feature    6222..6237
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     gene            complement(6340..6894)
                     /locus_tag="IE135_RS32460"
                     /old_locus_tag="GCM10010253_65770"
     CDS             complement(6340..6894)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006126492.1"
                     /locus_tag="IE135_RS32460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_65770"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_199889817.1"
                     /transl_table=11
                     /translation="MTHTSSSPWKSSPELSFRRAGEGDLAELVRLRDDAARWQIERGID
                     QWKPGELGPEHFGARLRAGEVWIATAGPGGPNAGAWELWWEDEPAWGVQPPVAGYVHRL
                     MTDRRTAPPGVGRALLAEAERRIAASGRPLCRLDCLTSNTRLRRYYEQAGYVVVGEQAG
                     KNGDGGRTYGVTLLEKRVGAG"
     gene            complement(7053..8942)
                     /locus_tag="IE135_RS32465"
                     /old_locus_tag="GCM10010253_65780"
     CDS             complement(7053..8942)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012379740.1"
                     /locus_tag="IE135_RS32465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_65780"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_199889818.1"
                     /transl_table=11
                     /translation="MSAVTGTSAGAGQAGPGPVPGRSPESTERPGPETPPDRTVPAPAA
                     APTPPPAPGPSPLRLLLARVRPHRGVLIRAGLLSLAGSGAGLAMPLMAKHAVDTFAEGR
                     SPVAPLVALTALVLAGACLSAYGSFLMSRTGEGVVLRARDQLVGRIMRLKVPAVDRLTP
                     GDLQSRVTSDTTLLRTVLSSGLVESFNSVLMLLGTLALMAYMDLTLLGVTLVVVVGIGA
                     VTSLLMPRIQRAQLKAQESVGAMGAALDRVLQAFRTVKASGAEERETAVVAAAARHAHD
                     RGVSVAKWASVTEVTMTMSIQLAFLAVLGVGGARVASGSLEISSLIAFLLYLFYLIGPI
                     GGLVEGWTGLQSGLAAVRRIDEVESLPGEPAEEPVALTKADGGPLGVTFQDVTFDYGDE
                     RAPAHQGVTFDVPAGGMVALVGPSGAGKSTVFSLLERFYDHEAGTITVGGRDIRDWPLA
                     ELRGSLAYVEQDAPVLAGTLRENLLFAAPDAGESELTAAVARTRLDALVERLPDGLDTA
                     VGHRGVTLSGGERQRIAIARALLRRPRLLLLDEVTSQLDAVNEQALRDVILELAERTTV
                     LVIAHRLSTVRHADRIVVLEEGRVRTAGTHEELMAGDELYRELATTQLAAEAR"
     gene            complement(8869..9366)
                     /locus_tag="IE135_RS32470"
                     /old_locus_tag="GCM10010253_65790"
     CDS             complement(8869..9366)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010071618.1"
                     /locus_tag="IE135_RS32470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_65790"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_199889819.1"
                     /sec_met_domain="PF13471 (E-value: 4.6e-25, bitscore: 79.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTEMTMPRRGAGAGGIRLRTAIAAAFVLARLKPGRLRRTLARCA
                     RGARPATYAETSEVLDAVIATSRRCASRYGCLPRSVAVALACRMSGVWPDWCAGVWATP
                     PFSPHAWVQAEGRTVGEQAEAADLRPLMVVTVREGVQGERGDGDVGGGGAGGPGPGSGE
                     IT"
     gene            complement(9363..9614)
                     /locus_tag="IE135_RS32475"
                     /old_locus_tag="GCM10010253_65800"
     CDS             complement(9363..9614)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006126488.1"
                     /locus_tag="IE135_RS32475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_65800"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_069735451.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.4e-27,
                     bitscore: 87.4, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 4.3e-15, bitscore: 47.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLRKGIAVTTTEYGGVLLDEKSGSYWQLNDTSVIVVETLAAGRA
                     PEAAVERIVAEFDVERAEAESDVAELTRRLVEARILRP"
     aSDomain        complement(9369..9614)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_IE135_RS32475_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="7.40E-28"
                     /identifier="RREFam002.1"
                     /label="IE135_RS32475"
                     /locus_tag="IE135_RS32475"
                     /protein_end="82"
                     /protein_start="0"
                     /score="87.4"
                     /tool="antismash"
                     /translation="MKLRKGIAVTTTEYGGVLLDEKSGSYWQLNDTSVIVVETLAAGRA
                     PEAAVERIVAEFDVERAEAESDVAELTRRLVEARILR"
     gene            complement(9611..11614)
                     /locus_tag="IE135_RS32480"
                     /old_locus_tag="GCM10010253_65810"
     CDS             complement(9611..11614)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010071617.1"
                     /locus_tag="IE135_RS32480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_65810"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_199889820.1"
                     /sec_met_domain="Asn_synthase (E-value: 7.7e-32, bitscore:
                     103.0, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGQLRDYFVVLPDSAAGAAAAGQLPVPGEAAGRSAAPDATGPAR
                     EVGDTLTVAHPSGRPWIVARPLVRRVSQIARGSDALVLIGPDRVPDAVLAGILEGARDR
                     TGLERRLARLPGLYHVVARLSGQSWIRGTATGLRRIYHARHPAAGTIASDRPAVLARLI
                     DAPLDDSALALRLLDFLPHPLSRRPVWRGIHETGAGHGLALPAAAPGTAAVPGPTEHRW
                     WEPPPGELPLAEGARKAGDAIAASVRAHVGGLDRISCELSGGLDSTALAFAARETGPAS
                     LSLLTVAARDRYSEDETWARRAVEAAGGTPATATRNTHSAATRGRPSAPALDHHVIPAD
                     DAPYFYADLASTAAELNDEPLPVAPGRARAELLLGRAHATGSRYHLTGYGGDEIFLGLP
                     HAYQDLFHGSPFTAWSHLGGLRHQLGWALLPTVKALFDRSTFPRWLAGAVTAAPQPVAR
                     TPLFSWGVRQSLHPWLTEHATALIAEEFRAAAEQAEPIDPRRGRHVDIDGVRMGARHFQ
                     AMEDIGMTIGLPVAAPFYDDRVLEATLAVRLPERISPWRYKPLLVEAMRGVVPDALLAR
                     TTKDHMASDEHQGLREHAPELVELWTGSRLAEHGLVDARRLLRLAAEPFSPVLVEHSIS
                     STVAGETWLRTAENAWPPPEPSLPTTPSEASL"
     gene            complement(11665..11796)
                     /locus_tag="IE135_RS32485"
                     /old_locus_tag="GCM10010253_65820"
     CDS             complement(11665..11796)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010071616.1"
                     /locus_tag="IE135_RS32485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_65820"
                     /product="keywimysin-related RiPP"
                     /protein_id="WP_107403431.1"
                     /transl_table=11
                     /translation="MKPQKQQKKAYVKPSMFQQGDFSKKTAGYFVGSYKEYWSRRII"
     CDS_motif       complement(11716..11796)
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MKPQKQQKKAYVKPSMFQQGDFSKKTA"
                     /locus_tag="IE135_RS32485_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       complement(11665..11715)
                     /prepeptide="core"
                     /locus_tag="IE135_RS32485_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="-1.40"
                     /molecular_weight="2006.3"
                     /monoisotopic_mass="2005.0"
                     /core_sequence="GYFVGSYKEYWSRRII"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MKPQKQQKKAYVKPSMFQQGDFSKKTA"
                     /leader_location="[11715:11796](-)"
     misc_feature    complement(12070..12085)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.76"
                     /tool="antismash"
     gene            complement(12319..12828)
                     /locus_tag="IE135_RS32490"
                     /old_locus_tag="GCM10010253_65830"
     CDS             complement(12319..12828)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015610344.1"
                     /locus_tag="IE135_RS32490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_65830"
                     /product="hypothetical protein"
                     /protein_id="WP_069735453.1"
                     /transl_table=11
                     /translation="MSVRATGRTGGRGRLKGVSLVVGGAVLFAAGLFVVVAGTGLSGAL
                     GMRVETFGRIDCDDTRTEKGQTVWHCSGETPAQQRANDAERERVAHEALRAHVDGVPRS
                     AEISRSRILFADHDGRMDPETITATQVFDGGRWYAHSSMLVGYGMIPLFLGAGTAAWGG
                     YRLRAG"
     gene            complement(13010..14632)
                     /gene="groL"
                     /locus_tag="IE135_RS32495"
                     /old_locus_tag="GCM10010253_65840"
     CDS             complement(13010..14632)
                     /GO_function="GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA]"
                     /GO_process="GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /gene="groL"
                     /gene_functions="other (smcogs) SMCOG1299: chaperonin
                     GroEL"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006133870.1"
                     /locus_tag="IE135_RS32495"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES; misfolded
                     proteins enter the barrel where they are refolded when
                     GroES binds; 60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES; misfolded
                     proteins enter the barrel where they are refolded when
                     GroES binds; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_65840"
                     /product="chaperonin GroEL"
                     /protein_id="WP_003967345.1"
                     /transl_table=11
                     /translation="MAKIIAFDEEARRGLERGMNQLADAVKVTLGPKGRNVVLEKKWGA
                     PTITNDGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVREGLR
                     NVAAGANPMALKRGIEKAVEAVSAALLEQAKDVETKEQIASTASISAADTEIGAKIAEA
                     MDKVGKEGVITVEESQTFGLELELTEGMRFDKGYISAYFATDMERMEASLDDPYILIVN
                     SKIGSVKDLIPLLEKVMQSGKPLLIIAEDVEGEALSTLVVNKIKGTFKSVAVKAPGFGD
                     RRKAMLADIAILTGGTVISEEVGLKLENAGLDLLGRARKVVITKDETTIVDGAGDSDQV
                     QGRVNQIRAEIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVR
                     NAKAAVEEGIVAGGGVALLQASAVFEKLDLTGDEATGANAVKLALEAPLKQIAVNGGLE
                     GGVVVEKVRNLPIGHGLNAATGEYVDMIAEGILDPAKVTRSALQNAASIAALFLTTEAV
                     IADKPEKAGAAAPGGMPGGDMDF"
     misc_feature    14751..14766
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.09"
                     /tool="antismash"
     misc_feature    14754..14768
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.78"
                     /tool="antismash"
     misc_feature    14785..14800
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.11"
                     /tool="antismash"
     misc_feature    complement(14788..14803)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.7"
                     /tool="antismash"
     gene            complement(14999..15205)
                     /locus_tag="IE135_RS32500"
                     /old_locus_tag="GCM10010253_65850"
     CDS             complement(14999..15205)
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003967346.1"
                     /locus_tag="IE135_RS32500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_65850"
                     /product="cold-shock protein"
                     /protein_id="WP_003967346.1"
                     /transl_table=11
                     /translation="MAQGTVKWFNAEKGYGFIAVDGGADVFVHYSAIQMDGYRTLEEGQ
                     RVEFEISQGQKGPQADMVKLAVG"
     gene            complement(15651..15929)
                     /locus_tag="IE135_RS32505"
                     /old_locus_tag="GCM10010253_65860"
     CDS             complement(15651..15929)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007265553.1"
                     /locus_tag="IE135_RS32505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_65860"
                     /product="MoaD/ThiS family protein"
                     /protein_id="WP_006126483.1"
                     /transl_table=11
                     /translation="MSVKVRIPTILRTYTGGQAEVPAEGTKLSEVIESLEKDHPGIAAR
                     VLDDQGKLRRFVNVYVNDDDVRFEGGLDAATPDGAGVSIIPAVAGGC"
     gene            complement(15965..17260)
                     /gene="thrC"
                     /locus_tag="IE135_RS32510"
                     /old_locus_tag="GCM10010253_65870"
     CDS             complement(15965..17260)
                     /EC_number="4.2.3.1"
                     /GO_function="GO:0004795 - threonine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thrC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010056010.1"
                     /locus_tag="IE135_RS32510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_65870"
                     /product="threonine synthase"
                     /protein_id="WP_069735454.1"
                     /sec_met_domain="PALP (E-value: 9.3e-63, bitscore: 204.0,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVQTIAGNATTAPVDLGPAAALSCRECGERFELGPLFACASCFG
                     PLEVAYDLPTGSAEELRKRIEAGPDNIWRYAPLLPVPADVADKPNLNPGFTKLVKADNL
                     ARELGVTGGLYVKDDSGNPTHSFKDRVVAIAVEAARAFGFTTLSCSSTGNLAGAVGAAA
                     ARAGLRSCVFIPHDLEQGKVVMAAVYGGELVGIEGNYDDVNRFCSELIGDPLGEGWGFV
                     NVNLRPYYGEGSKTLAYEICEQLGWRLPDQIVIPIASGSQLTKIDKGLQELIKLGLVED
                     KPYKVFGAQAEGCSPVSAAFKGGHDVVRPQKPNTIAKSLAIGNPADGPYVLDIARRTGG
                     AVEDVTDEQVVDAIKLLARTEGIFGETAGGVTLGVTKKLIEAGVIDPALTTVVVNTGDG
                     LKTLDAVSATSQATATIKPSLDAFRAAGLGTA"
     misc_feature    complement(17243..17257)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.51"
                     /tool="antismash"
     regulatory      complement(17279..17406)
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(17514..17534)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.9"
                     /tool="antismash"
     gene            17560..18510
                     /locus_tag="IE135_RS32515"
                     /old_locus_tag="GCM10010253_65880"
     CDS             17560..18510
                     /EC_number="2.4.1.266"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511020.1"
                     /locus_tag="IE135_RS32515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_65880"
                     /product="glucosyl-3-phosphoglycerate synthase"
                     /protein_id="WP_199889831.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.6e-12,
                     bitscore: 38.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEEVERWLTRRSWSSGDRPLNRLTDARAADPRRTSVSVVLPALN
                     EEATVGAIVATIRRELMEKIRLVDELVVIDSGSTDATAAVARAAGARVVHRDTILPRIP
                     AVPGKGEVLWRSLLVTSGEIVCFVDADLKDFSADFVSGTVGPLLTDPTVQFVKAMYDRP
                     LGGSAGQGGRVTELVARPLLNLHWPQLAGFVQPLGGEYAVRRSLLERLPFPVGYGVELG
                     LLVDALHTVGLDALGQVDVGVRVHRHQDGQALGRMAAAIYRTAQLRLSRGHLVRPVLTQ
                     FERGEEGFVPRTHAVDTEERPPMREIAEYAERHAA"
     gene            18637..20028
                     /locus_tag="IE135_RS32520"
                     /old_locus_tag="GCM10010253_65890"
     CDS             18637..20028
                     /EC_number="2.4.1.15"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018101576.1"
                     /locus_tag="IE135_RS32520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_65890"
                     /product="trehalose-6-phosphate synthase"
                     /protein_id="WP_069740895.1"
                     /transl_table=11
                     /translation="MVSEHTSSSHAQVLVASNRGPITYTLDEDGTLDSKRGGGGLVSGL
                     SAVDDKLWVCAALGDGDREAVRRGVGEPGVRMLDIDAEVHADAYNGIANSVLWFVHHLL
                     YQTPVEPVFDTEFRRQWAAYEAYNRAFAQALAEEAGPEAAVLVQDYHLALVPGMLRELR
                     PDLRIGHFSHTPWAPVDYFRLLPDDIAEQLLRGILGADRAAFLTRRWSDAFIGCCTEIL
                     GGTGRTRIGVHGLGADADFLRRRSHEADVDERMAALREQVGENRKTIVRVDRTELSKNI
                     VRGLHAYRTLLETRPEWRERVVHIAFAYPSRQDLSVYRDYTAAVQSLATEINGAYGTDG
                     WTPVVLHVKDDFARSLAAYRLADVALVNPIRDGMNLVAKEVPVVSDHGCALVLSREAGA
                     YEELGEDAIVVNPYDVTGTAEALHEALTMSVDERSGRTKRLAEAATALPPQRWFLDQLE
                     ALRQE"
     gene            complement(20082..20933)
                     /gene="otsB"
                     /locus_tag="IE135_RS32525"
                     /old_locus_tag="GCM10010253_65900"
     CDS             complement(20082..20933)
                     /EC_number="3.1.3.12"
                     /GO_function="GO:0004805 - trehalose-phosphatase activity
                     [Evidence IEA]"
                     /GO_process="GO:0005992 - trehalose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="otsB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018958814.1"
                     /locus_tag="IE135_RS32525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_65900"
                     /product="trehalose-phosphatase"
                     /protein_id="WP_069740894.1"
                     /transl_table=11
                     /translation="MGSHPERLPNPTTPAGREGLDAVLARPDRAVVALDFDGTLADIVP
                     DPEQARAHPGTVAALAALAPKVAAIAVITGRPAGVAVRYGGFAGVPGLERLVVLGHYGA
                     ERWDAVTGTVRAPAPHPGVTAVRAELPGVLHDVGAWNGTWIEEKGQALAVHTRRAQDPQ
                     AAFESLRGPLGELAAKHGLIVEPGRLVLELRPPGMDKGVALAGFVAELDAESVIYAGDD
                     LGDLAAFAAVEKLRGEGPDGVPGLLVCSGSAEVPELAERADLSVPGPAAVVDFLAALAD
                     RL"
     misc_feature    complement(20933..20951)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.82"
                     /tool="antismash"
ORIGIN
        1 ctcgcagcgc aatggctcga ccgaggcgtc accaccgact acctcaccag caccctcacc
       61 gccggactcc ccgcacaggt cgactccccc gtcggactcc tccgccgccg cctcaccgac
      121 aaactgccgc cccgaatccc ggccacccca agcaccccgc ccaacacccc cgaccccact
      181 gccacccgcc gcctcctcgt cgaatgcacc gactgcggcc gccccggaca gcccgaagcc
      241 ctccccgacg gcctctgcca cccctgccac cgaacccaca ccgcccacga cgacaccaca
      301 ccccccgacc ccacccagat cgccgccgtc aaagcccaca tggccaacct ccgccacctc
      361 ctcaaacccg tctgaggtgc gggtactctc tggcgatggc cgatcagtca gtagcagcgg
      421 gagtcagtct cgcgggtgtg atggcgcact gcggcgggag ccccgtgggt gccgtggagc
      481 ttctggtggg ggcgatagcc tccgcgccga cggctccgga gccctatgcg gccctcgcgg
      541 cgttgtggca gggcctccgc ccggacggcc tgcgggagag cctcgcagag gacggctcct
      601 tgagtaccgt gccggcgcag gcgtacttcc tgttcctcga aggggacatg gacaacgcgg
      661 tgatggccct cggttcggtc acgggtgtgc ggcccgacgt cgcctggggt gccgcgccct
      721 ggttcggcga tgcgcggttt ctcggtgcgg tgagtgctgc ggcgctggcc gaggcgtgtc
      781 tgcggacctt ggactacggc cgcgacctgg acaccgacgc gatgcgggag cggttcgcgc
      841 cctggttcca tgccctcgac gtggtgtccg aacgggaccc ggcacctgag tcgctggccg
      901 ccatggcccg gctgccccgg gcctgcggcc ggtacgaact gtccttcgcc ctgtgcgacc
      961 gtgcggacgc cgtcgatccg gtcatgtgga cagcgctcgc gcgagcggcc acctggcgcg
     1021 cgatgggcaa cctggatcag gctgccgcgt ccttcgaacg cgccctgctc ctggagcccg
     1081 gcaactggtc cctctacctg gacctggcag acctgcgtgc cgagcagggc gacttcgccg
     1141 cagccgcgag catcgtcgaa cagggcctgc agcacgaacc tcgcgaagcc accctgcgcg
     1201 cggcgagcgc tgcctaccgg acacgcctcg tcggctcggc cgacgacctc acggccctga
     1261 tcgccctggc cccctcgctc gccgacaccg cctaccggaa cctgctgatc gactacgcgt
     1321 gcgcaggacc gcaactccct ccgggactgg ttgccgaggc ccaccgaatc caggaaagct
     1381 gaacgggtag tcgtgaacag tcagatgttc gagctgatgt ggggtggcgt cgcgctcgtg
     1441 ggcggggggc tcctggccgc aaacgtccga ggggcggccg aacggttcca ggcgatgtcc
     1501 tacgcctacc ggtcgtggcc cgccagtgtc gtcacatgca gagtgatcgg tggcgccttc
     1561 gctctcgccg gggcaggggt ccttgttgac gccggactcc ggaccatggg cgggtgacgg
     1621 tgtgcccgac ccggcgtcgt cgcagatcgc gccggtgacg gcgtgcgctc acgccaccgc
     1681 cttcgccaga tccaccgcgc cggcctcctg cgtctcgggc agcagtgcgt acccctgctg
     1741 ctggtacagc gcgatgttgc ggtggctggc cgcgccggtc gacaggacga tgcggccgca
     1801 cccctccccc gccgactcgg ccaggcgcag cagccagcgg cccacgccct gcccccgcag
     1861 gtcgggggcg acggccaggc gtcccacgtg gaggtcggtg ccggtgcggc gggtgcggac
     1921 aggtctgcgc cgaggagctc cgcgccgggt gcgagcacgt cggtcagcca ctgccccacg
     1981 gcggggccga gcgcgttggg gcgggtactg cagaccagaa cgaggacgcg cagccgtttc
     2041 gttgtcatag aaatgaaata agccggtagg ttggttacat gtcaacgaac gagacggctc
     2101 ccccggtcga ctggctcacc cccgacgagg accgcgcctg gcgggcgtac ctccgcatgg
     2161 tgaccgccgt ccaggtcggc gtcgcacagg acctggccgc actcggcctg tccgagccgg
     2221 actacgaggt gctcagcacc ctgtccgagc gcgaggacgg caccagcacg ctgcacgaac
     2281 aggccgccaa gatgggctgg tcgcgcagtc gcctgtcccg gcacgcctcc cgcatggagg
     2341 cacgcggact catccgccgc gcccccgacc ccaccgacgg ccggggctgc ctcctcgtcc
     2401 tgacctcggc gggctgggac gtgctacggg acgccgcgcc ctcccatgtc acctccgtac
     2461 ggcggcactt cgtcgaccgc ctgacaccgg aggagctcgc cacgctgggc cggatcgccg
     2521 ggaagctcag cgccgaccgg taggggcggc cgggaggagg cggcggtgcc gggcccgcct
     2581 caggcgaggg ccgcgaccag cgacgcgaag gcgccgatga ggacggccac gcgcgcgtag
     2641 tggtagcggt cccagcggtt catctgctct ttccagtcct cgggccggtt ctccgaggtc
     2701 cacgtcttac cccggtcgtt gatcgggacg agcagcagaa gcgacatgag cacgccgagg
     2761 agcaacagcg cgcccgccgc gacgaccagc cccgcgcccg gctcgcccca cccggccacg
     2821 gcccagatcg cgctcaggac gagtgaaccg atgtaccaga acggcatcac cgccccaagc
     2881 atccggcccc cgtggcttcg cccgcgctga gcactgtcgt cgggcagcgc gtccaggatc
     2941 cggttgatga caaaggcgac ggagaactcc acccccacca gcagtccgac gatcacggtg
     3001 gtgacgacct caagtacgtc gagcatgatg acccctctcg gaatctagcg atgctagatg
     3061 atggtgcaac gctagacctg ctgccgcttg attgtctagc gatgctaggg tcggtacatg
     3121 tcggtccagg aacgcaagga acgggaacgg gcgaaccgcg agcgcctcat cgtggcgacg
     3181 gctcgcgaac tcgccgacca gcaggggtgg gacgcggtca ccacgcgccg gctcgccgag
     3241 cgcatcgaat acagccagcc cgtcctctac agccacttcc gcggcaagcg cgagatcatc
     3301 ggcgcggtcg cgctcgaagg cgccaccgag atggcttcgg cgctgcgggc cgccagctcg
     3361 ggcgcggacg gccgccgcac ccgggtcgcc gccctcgccc acgcgtacct ggagttcgcc
     3421 gagcggaacc ctgcggtcta cgacgccctg ttccagctcg acggcggcct ggccttcgcg
     3481 cgcgaggaca ccccggaacc gctgaaggac gccttcgccg cgctgctgga gaccctcggc
     3541 gaggtcgccg gggagggcgt gcacccggcg ctgttcaccg aactcttctg gtcggccctg
     3601 cacgggctgg ccaccctgac ccgggcgggg cggctcctgc cggagggcgc gggggagcga
     3661 ctggatctcc tggtggaacg gctcgccgtg ctctgaccgt ccccgtgcac gtacaccgac
     3721 tgcccgtcac gccccggagg ggaactgttc ggggaaccgg cgggggctgt tcgggaaaac
     3781 gccgggactg ttcgggagac cggccgggag aaccggcccc cgcctcctca ccccgcccat
     3841 ctccccgtca ggaacgtcag cgcgacgagc gtcgtcaccg gggccgccac acacaggtac
     3901 gccgtcctga accacggccg acgcaggctc agcgccgcca ggccgatcca cagcggccac
     3961 cacagcagcg tcgcgcgcgg gacggacgtg taccagtacg aggtgcccag cgcccagaga
     4021 ctgagggcca cgtacaccgc ttccggccag cggcgtcggc gtaccagcag caccaccagg
     4081 gcgagcccca ccaccatcgc cgccaactcc gcctggaaca tgaacgcgta gccggtcgac
     4141 tgcgtaccgc cgaacgcccc ggtccaggtg ttcgcccacg cctcccacgg ggcgtggaac
     4201 gtgcggtacc aaccgcgttc ctgcgcgtgc ttccaggcca cccagtcacc ggtccgcgcg
     4261 tgcagatacc agctgtacgc ggccgggggc agcgccggaa gcagcgtcca gcccgccgca
     4321 cgccacctcc gccggccctc gcccgcacgt acggacagca ggaacagcag cccgacggcc
     4381 gccgcgagga acaggccgct cacgcgcacc gccgtcgccg acgtggtcag tacggcggcg
     4441 agcgcccacc ggtgcttcat cgccacgagc caggcgggca gcgcgaacgc gaggaacagc
     4501 gcctccgtgt aacccgccgc caggaacacc gcgcagggcg agagcaggaa gaggacagcc
     4561 gtacgggggc ccgccgcgtc ctccggcaga tacgcccgcg cgagacgggc cagggccagt
     4621 acggcaacgg cccccgcgat gaacgagatc agcagcccgg ccgccgtcca gtggggcacc
     4681 accgtgtgca cggcgcggag caggaggggg tagccgggaa agaacgcctc ccggttgtcc
     4741 cagccgctcg tccacggtcc cgcgcccgcc gggaagtagc cgtcgcgggc tatgtggagg
     4801 tagtggttcg cgtcccactg ctggaacggc gccaggaccg gggccgcctc ccgtacgccg
     4861 gactgcgcgg gaaacagcca gcgggcgaag tgggccgtga tccacaggga gacgcgggtc
     4921 aggagataga gccacaggat gccgcgatcg gcgggagcca ggcggaaccg tgccaaccgg
     4981 ggctcggccg accggggttc gggtgcggga cggacaggag acggccgcag ccccggggag
     5041 agcgtggaca acgcaggcac ctttcgggcg cgcctcgcgg gtacgtcggg gcgcgccgga
     5101 tcgcccggag agccgccggg gcacggaagg gaagaagagg agaagggaag ggtcgaggcc
     5161 gcgcggcggc gtcagggcgt cgacgcgccc ccatcggttg tcgccgatgc cgtcggtggc
     5221 gtcgtgctcg tacgcgtacg cgtgggcggc ccgcccggct cggtggtccg gcccgacggc
     5281 ccctccgccc cccgcgtccc cgcgctcccc ggcaccgtgg tgctcggcga cggcggcgtt
     5341 gacggctgct cggtgggcag gccctccgac ggtacgggcg aggggtagct gggcgacggg
     5401 ttcgtggccg gggccaccgg ctgcggccgc accggcagca ggcccaccgc gaccgcgccg
     5461 cccccgccga cgaccaggca cacccccacc gcgaccacgg ccatccggcg tcgctgcgcg
     5521 cgcatgccgc gccgggtgat gctcgacgcg gtgtccgggg cggtgagggc ctgcccgaac
     5581 tcaccggcct cccggaacag ggaccgcaac ggatcctgcg gctccttcgg atcccgcggt
     5641 tcagacatca ggagcctcct cgatgcgggg gtcgcgcagc cggtgggcga gcgccgcccg
     5701 gccacggacc agatgcgtct tgatggtgct ggtggaaagc ccggtctccc cggcgatctg
     5761 ctcgaccgtg aggtcgcaca ggtagtgcag ggtcagcgtc cgccgctgct gggcgggcag
     5821 ctcccgcagc gcgtcgacca ggaccacatg gtccgggtcc ggcggcgcga cgtgctccgc
     5881 cccaccgctc ccccggcccc acgcgtcagc cgaccgccgc cggaaacgcc aacggctcac
     5941 cgccagccgc caggcgaccg tacggatcca cgcctcgggc tgcccgtccc gctccagccg
     6001 cccccgccgg acccacgcct tgacgaacgc ctcctgcacg acgtcctgcg cctcctggag
     6061 gtcgccggtc atcacgtaca actggccggt gagacgtgcg accgcctggg cgtagaactc
     6121 ttcgaactcc tcgacggtca aaagttgctc ccggatcttt cgcttcaccg ggtatacgcc
     6181 tgccgtcggg catccggtct acagcgtcga ccgagcatcc gggtgacggt cgtcacagcc
     6241 gggctcagcc tgccgggcgg ggattcagcc gacgctcagc ccggcccggc ggggattcag
     6301 ccagcgctca atccgctccg gcgggggttc agccgccgct caacccgccc ccacccgctt
     6361 ctccaacagg gtgaccccgt acgtccggcc gccgtccccg ttctttcccg cctgctcgcc
     6421 gaccaccacg taccccgcct gctcgtagta gcggcggagc cgggtgttcg acgtcaggca
     6481 gtcgagtcgg cacagcggcc ggcccgacgc ggcgatccgg cgctcggcct ccgccagcag
     6541 cgcacgcccg accccgggcg gggcggtgcg ccggtcggtc atcaggcggt ggacgtagcc
     6601 cgccaccggc ggctggacgc cccaggccgg ctcgtcctcc caccacagct cccacgcccc
     6661 ggcgttcggc ccgccgggac cggcggtggc gatccacacc tcgcccgcac gcaaccgcgc
     6721 cccgaagtgt tccggcccca gctccccggg tttccactgg tcgatgccgc gctcgatctg
     6781 ccagcgcgcg gcatcgtccc ggaggcgcac gagctcggcc agatccccct cccccgcccg
     6841 ccggaacgac aactcgggcg acgacttcca gggagaagag cttgtatgcg tcatgccgcg
     6901 atccttcctc aacaggtttc gcggtacggg acggccggca gcctgcgacc agtcgacctc
     6961 ctcggcgaac cggcctctca gttcctcgtt cgcgccacac ccaccgtccg cgtccgcctc
     7021 gccgcccccg ccgtccgcac cctccggatt tctcaccgcg cctccgccgc cagctgggtc
     7081 gtcgccagct cgcggtacag ctcgtccccg gccatcagct cctcgtgcgt gcccgccgtg
     7141 cgcacccggc cctcctccag aaccacgatg cggtccgcgt gccggactgt ggacaggcgg
     7201 tgcgcgatca ccagcaccgt tgtgcgctcg gcgagttcga ggatcacatc gcgcagcgcc
     7261 tgctcgttga ccgcgtccag ttgcgaggtc acctcgtcca ggagaagcag ccgggggcgg
     7321 cgcagcaggg cccgggcgat ggcgatgcgc tggcgttcgc cgccggagag ggtgacgccc
     7381 cggtggccga ccgccgtgtc caggccgtcc ggcagccgct cgaccagggc gtccagccgg
     7441 gtgcgggcga ccgcggccgt cagctcgctc tccccggcgt ccggggcggc gaagaggagg
     7501 ttctcccgca gcgtcccggc gagcaccggc gcgtcctgtt ccacgtacgc cagtgagccc
     7561 cgcagttcgg ccagcggcca gtcgcggatg tcccggccgc ccacggtgat cgtgccggcc
     7621 tcgtggtcgt agaagcgctc cagcaggctg aacaccgtcg acttgcccgc cccggacggg
     7681 cccaccagcg ccaccatccc gccggccggc acgtcgaacg tcaccccctg gtgggcgggg
     7741 gcgcgctcgt ccccgtagtc gaaggtcacg tcctggaagg tgaccccgag cgggccgccg
     7801 tccgccttcg tcaacgcgac cggctcctcg gccggttctc cgggcagtga ctccacctcg
     7861 tcgatccggc gcaccgccgc cagcccgctc tggaggcccg tccagccctc gaccaggccg
     7921 ccgatcgggc ctatcaagta gaagaggtac agcaggaacg cgatcaggga ggagatctcc
     7981 agcgagccgg acgcgacccg tgcgccgccg acgcccagca ccgccaggaa cgccagctgg
     8041 atcgacatcg tcatcgtgac ctcggtgacc gaggcccact tcgccaccga cacgccccgg
     8101 tcgtgcgcat gccgcgccgc cgccgcgacc accgcggtct cccgctcctc cgccccgctc
     8161 gccttgaccg tacggaacgc ctggagcacc cggtccaggg ccgcgcccat cgcacccacg
     8221 gactcctgcg ccttgagctg cgcccgctgg atgcgcggca tcagcaggga cgtcacggcc
     8281 ccgatgccga cgacgaccac cagcgtcaca ccgagcagcg tcaggtccat gtacgccatg
     8341 agagcgagcg tgcccagcag catcaggacg ctgttgaacg actcgacgag tccgctggag
     8401 agcaccgtac ggaggagggt cgtgtcgctc gtgacccgtg actggaggtc gccgggcgtc
     8461 agccggtcca ccgccgggac cttcaaccgc atgatgcggc ccaccagttg gtcgcgtgcg
     8521 cgcaggacga cgccctctcc cgtccgggac atgaggaagc tcccgtacgc ggagaggcag
     8581 gccccggcca gcacgagcgc ggtcagcgcg acgagcgggg ccacgggcga gcggccttcg
     8641 gcgaacgtgt ccaccgcgtg cttcgccatc agcggcatcg ccagacccgc cccggacccg
     8701 gcgagcgaga gcaggcccgc ccggatcagg acgccccggt gcgggcggac ccgggccagg
     8761 agcaggcgga ggggcgaagg gccgggggcg ggcggaggcg tgggggcggc agccggggcg
     8821 ggcacagtcc ggtccggagg tgtctccggc cccggtcgct ccgtgctctc aggtgatctc
     8881 cccggaaccg ggcccgggcc cgcctgcccc gcccccgccg acgtccccgt caccgcgctc
     8941 accctggacc ccctcgcgta ccgtcaccac catcagagga cgcagatcgg cggcctctgc
     9001 ctgctccccg accgtacgtc cttccgcctg cacccaggcg tgcggggaga acggcggggt
     9061 cgcccacacc cccgcgcacc agtcgggcca gacaccggac atccggcagg ccagggcgac
     9121 ggccaccgag cggggcaggc agccgtaacg gctcgcgcag cggcggctgg tggcaatgac
     9181 cgcgtccagc acctccgacg tctcggcgta cgtggccggg cgcgcgcctc gggcgcaccg
     9241 ggcgagcgtc cggcgcagcc ggccgggctt gagccgggcc aggacgaacg cggcggcgat
     9301 ggcggtgcgc agccgtatcc cgcccgcccc ggcgccccgg cggggcatcg tcatctcggt
     9361 ggtcatggcc gcaggatcct cgcctcgacg agccggcggg tcagctccgc gacgtccgac
     9421 tcggcctcgg cccgctcgac gtcgaactcg gcgacgatcc gctcgacggc ggcctccggg
     9481 gcgcggcccg ccgcgagggt ctcgaccacg atgacgctgg tgtcgttcaa ctgccagtag
     9541 ctgccgctct tctcgtcgag gagaacgccg ccgtactcgg tggtcgtgac ggcgatgcct
     9601 tttctgagct tcacagggat gcctcgctgg gggtggtggg gagggacggc tcgggtgggg
     9661 gccaggcgtt ctcggccgtg cggagccagg tctccccggc cacggtggag ctgatggagt
     9721 gttcgaccag gaccggcgag aagggctcgg ccgccagtcg cagcagtcgg cgggcgtcga
     9781 ccagaccgtg ttcggcgagg cgggagcccg tccacaactc gaccagttcc ggagcgtgtt
     9841 cgcgcaggcc ctggtgttcg tcggaggcca tgtggtcctt cgtcgtccgg gccagcagcg
     9901 cgtccggcac caccccgcgc atcgcctcga cgaggagcgg tttgtagcgc caggggctga
     9961 tgcgctccgg caggcgtacc gcgagggtcg cctccaggac ccggtcgtcg tagaaggggg
    10021 cggcgaccgg cagcccgatc gtcatgccga tgtcctccat cgcctggaag tgccgggccc
    10081 ccatccgtac gccgtcgatg tcgacgtgcc gtccccgccg cgggtcgatc ggttcggcct
    10141 gctcggcggc ggcccggaac tcctcggcga tcagggcggt cgcgtgttcg gtgagccagg
    10201 ggtgcaggga ctgccgtacg ccccaggaga acagcggggt ccgggcgacc ggctggggtg
    10261 cggcggtgac cgccccggcg agccagcggg ggaacgtcga acggtcgaac agcgccttca
    10321 ccgtgggcag gagcgcccag ccgagctggt ggcgcaggcc ccccaggtgg ctccaggcgg
    10381 tgaacgggct gccgtggaag aggtcctggt aggcgtgggg caggccgagg aagatctcgt
    10441 cgccgccgta gccggtgagg tggtagcggg agccggtggc gtgggcgcgg ccgaggagca
    10501 gttccgcgcg ggcccggccg ggggcgacgg ggagcggttc gtcgttcaac tcggcggcgg
    10561 tggaggcgag atcggcgtag aagtaggggg cgtcgtcagc agggatgacg tggtggtcca
    10621 gggcgggggc ggaggggcgg ccccgggtgg cggcggagtg ggtgttccgg gtcgccgtcg
    10681 cgggggtgcc gcctgccgcc tcgaccgctc tgcgcgccca ggtctcgtcc tcgctgtagc
    10741 ggtcccgggc ggccacggtc agcagggaca gcgacgcggg gccggtctcg cgggcggcga
    10801 aggcgagggc ggtggagtcc agtccgccgg agagttcgca gctgatccgg tccaggccgc
    10861 cgacatgggc ccgtacggag gccgcgatgg cgtccccggc ctttcgcgcc ccctccgcca
    10921 ggggaagttc gccgggcggc ggctcccacc agcgatgctc cgtgggaccg gggacggcgg
    10981 ccgtgcccgg tgctgcggcg ggcagggcca ggccgtgccc ggcaccggtc tcgtggatgc
    11041 cccgccacac ggggcggcgg ctcagggggt gcggcaggaa gtccagcagc cgcagcgcca
    11101 gcgcgctgtc gtccaggggc gcgtcgatca ggcgggccag gacggcgggg cggtcggagg
    11161 cgatggttcc ggccgccggg tgccgggcgt ggtagatccg gcggagtccg gtggcggtgc
    11221 cccggatcca gctctgcccg gacagccggg cgaccacgtg gtagaggccg ggcagccggg
    11281 cgaggcggcg ctccaagccg gtccggtcgc gggcgccctc cagaatcccg gcgagtacgg
    11341 cgtcggggac gcggtccggg ccgatgagga cgagggcgtc cgagccccgg gcgatctggc
    11401 tgacccggcg gaccagcggg cgggcgacga tccagggccg gcccgagggg tgggcgacgg
    11461 tcagggtgtc gcccacctcc cgggcgggcc cggtggcgtc cggcgcggcg gaccgcccgg
    11521 cagcctctcc cggtacggga agctgcccgg ccgctgccgc tcccgccgcg ctgtccggca
    11581 ggacgacgaa gtagtcacgc aactggccgg gcatcttcac ctttcggaag ttctcacgcg
    11641 gtgcacagga aacggatcgg cggatcagat gatccgccgg ctccagtact ccttgtacga
    11701 gccgacgaag tagccggcgg tcttcttcga gaagtcgccc tgctggaaca tcgacggctt
    11761 cacgtaagcc ttcttctgct gcttctgcgg cttcatgaca ccttcccttc tgtgcggttg
    11821 acgcccgtta tgcccaaagg acttctgcat aactggagtt actggtgcga cgggtgttcg
    11881 tcatgcgaac accagggcca tcatgtccga ccgttgaacc ggtacgcgtg attccgactt
    11941 accgcatgaa gttggctgga tagcgcgagc ggcgaggtgc gtcgcggacc ggttcggggg
    12001 cctccgcccg ggcccggtcg ccccgacgtc cgccgtgtgc agtcgcacac cgccccgccg
    12061 gaggggcttc gtggactgga ccaatgactg gacgtggtcg ccggacccta cggtgagctg
    12121 ccacgacggg gagcggccga caggaggccc ggggaaccgg ccggagcggg ccgcggggcg
    12181 gctccgcgac cgctttaccc cagggagccc gggcgcgcca ccgccctcgg caggggtgcg
    12241 ccgaaacgca ctgccgtacg ggagtggcca cggcaagtag tcattcggcc acgccgaggg
    12301 cccgcgctgc cccgtccgct accccgcgcg cagccggtag ccgccccagg ccgccgttcc
    12361 cgcgcccagg aacagcggga tcatgccgta gccgacgagc atcgaggagt gggcgtacca
    12421 gcgtccgccg tcgaacacct gggtcgcggt gatcgtttcg gggtccatcc ggccgtcgtg
    12481 gtcggcgaag aggatcctgc tgcggctgat ctccgcggac cggggcacgc cgtccacatg
    12541 ggcgcgcagg gcctcgtggg ccaccctctc gcgctccgcg tcgttggcgc gctgctgggc
    12601 gggcgtctcg ccggagcagt gccagacggt ctggcccttc tcggtgcggg tatcgtcgca
    12661 gtcgatgcgg ccgaaggtct ccacccgcat accgagggcg ccggagagac ccgtcccggc
    12721 caccacgacg aacagccccg ccgcgaacag cacggccccg cccacgacga gcgagacccc
    12781 cttgagccgc ccccggccgc ccgttctccc cgtagcacgc acgctcatgc ccgtaccgcc
    12841 ccccgtgtcc gtaagaccgc ggcctcgccc cattgtcccc ggacacgccc caggggcggc
    12901 acctccgtga aggagatacc gcccctgggg gacgtacctg cgtactcgac gtactggacg
    12961 tactcggcgt acgcggaacc tcgatcgacc ggcgcggagc cggaaccgat cagaagtcca
    13021 tgtcaccgcc cggcatgccg cccggagcgg ccgcgccggc cttctcgggc ttgtcggcga
    13081 tgacggcctc ggtggtgagg aacagcgcgg cgatggacgc ggcgttctgc agggcggagc
    13141 gcgtgacctt cgccgggtcg agaatgccct cggcgatcat gtcgacgtac tcgccggtcg
    13201 cggcgttgag gccgtgaccg atcggcaggt tgcggacctt ctccacgacg acgccaccct
    13261 cgagaccacc gttgacggcg atctgcttga gcggggcctc cagcgcgagc ttcacggcgt
    13321 tggcgccggt cgcctcgtca cccgtgaggt cgagcttctc gaagacggcc gaggcctgga
    13381 gcagagccac gccaccaccg gcgacgatgc cctcctcgac ggcggccttg gcgttgcgca
    13441 ccgcgtcctc gatgcggtgc ttgcgctcct tgagctccac ctcggtggcg gcgccggcct
    13501 tgatgacggc cacgccgccg gccagcttcg cgaggcgctc ctggagcttc tcgcggtcgt
    13561 agtccgagtc ggagttctcg atctcggcac ggatctggtt gacgcgaccc tgaacctggt
    13621 cgctgtcacc ggcgccgtcg acgatcgtcg tctcgtcctt ggtgatgacg accttgcggg
    13681 cacggccgag caggtccagg ccggcgttct ccagcttgag accgacctcc tcggagatca
    13741 cggtgccgcc ggtgaggatg gcgatgtccg cgagcatggc cttgcggcgg tcgccgaagc
    13801 ccggggcctt gacggcgacg gacttgaacg tgcccttgat cttgttgacg accagggtgg
    13861 agagcgcctc gccctcgacg tcctcggcga tgatcagcag gggcttgccc gactgcatga
    13921 ccttctccag cagcgggatc aggtccttga cgctgccgat cttcgagttg acgatcagga
    13981 tgtacgggtc gtcgagcgac gcctccatac gctccatgtc ggtggcgaag tacgccgaga
    14041 tgtagccctt gtcgaagcgc ataccctcgg tgagctccag ctccagaccg aaggtctggg
    14101 actcctcgac ggtgatgacg ccttccttgc cgaccttgtc catcgcctcg gcgatcttgg
    14161 cgccgatctc ggtgtcggcg gcggagatgg aggcggtcga agcgatctgc tccttggtct
    14221 ccacgtcctt ggcctgctcc agcagagcgg cggagacggc ctcgacggcc ttctcgatac
    14281 cgcgcttgag ggccatcggg ttggcaccgg cggcgacgtt gcgcagaccc tcgcggacga
    14341 gcgcctgggc gagaacggtg gcggtggtcg taccgtcgcc ggcgacgtcg tccgtcttct
    14401 tggcgacctc cttgaccagc tccgcaccga tcttctcgta cgggtcctcg agctcgatct
    14461 ccttggcgat ggaaacacca tcgttggtga tcgtgggcgc gccccacttc ttctcgagga
    14521 cgacgttacg gcccttgggg ccgagggtga ccttgacggc gtcggcgagc tggttcatcc
    14581 cgcgctcgag accgcgccgt gcctcctcgt cgaacgcgat gatcttggcc atgtgaagtg
    14641 gtcctcccgg acaggggtgg attgctccgg accgagaggc gcccgcgacg gacggcctgc
    14701 gtgcgtggtg gttccttgcc ccaccgcgcc tgcgggcctc accggcccgg tccaagtttc
    14761 tgtcactctc acctggagag tgctaacgcc aatgattagc actcgacccc cgagagtgca
    14821 agcgccttcg gccggtgccc gccatgcggt cgagggcgcg gagcgcgacc ggctcccgga
    14881 cgcgcgcacg tcgtcgcccc ccccttgaac gcgcgtaagg cccgatcccc tggaattcgc
    14941 cgatcccggg gtcgggccct acgtgcgtga gtggtgtcgt cggacgaccg cgccgagctc
    15001 agccgacggc gagcttgacc atgtcggcct ggggcccctt ctggccctgc gagatctcga
    15061 attcaactcg ctgaccctct tcgagggtgc ggtacccgtc catctggatc gcgctgtagt
    15121 ggacgaaaac atccgcacca ccgtcgaccg cgatgaagcc gtaccccttc tccgcgttga
    15181 accacttgac ggtgccctga gccatgccta actcccctat tactggccct tgcacgggac
    15241 cgcacttcgc gggcccgggt cggaactcac cctccgacag gagagggtgc gcggcgccgc
    15301 agcgcgtcga ccgcggctga atgtatccgc ccaactgccc tctgcaacag gtcaatcgga
    15361 cgagaattcc gggcgcggcg gaacacgcga atatgcgggt ttgctgagat ttacgggcaa
    15421 gtcgggccag gcaaagggca cttatgccgc aagaggttca ggtactttgg ctgcttctta
    15481 tcggggccgg gcgcattctc atatgcgggc ggcacgggca gcggatgggg cttccccaac
    15541 tgtaccgcgc tcaaccatgc agaattgccc cctccgcttc tctcgcggag ggggcaacag
    15601 gggtcacaca gaggtgcggc gggggccgcc gtggagcggc cccgggcggt tcagcagccg
    15661 ccggccaccg cggggatgat cgagacgccg gcgccgtccg gggtggccgc gtccaggccc
    15721 ccctcgaagc gcacgtcgtc gtcgttgacg tacacgttca cgaagcggcg cagcttgccc
    15781 tggtcgtcca ggacgcgggc cgcgatgccc gggtggtcct tctccaggga ctcgatgacc
    15841 tcggagagct tcgtgccctc cgccggcacc tcggcctggc cgcccgtgta cgtacggagg
    15901 atggtgggga tgcggacctt gacgctcatg gtggtgccct tcttccttcg ttacggggtg
    15961 gtcgtcaggc ggtgccgagg cccgcggcgc ggaacgcgtc caggctcggc ttgatggtgg
    16021 ccgtggcctg cgaggtggcg gagaccgcgt cgagcgtctt caggccgtcg ccggtgttga
    16081 cgacgacggt ggtgagcgcc gggtcgatga caccggcctc gatgagcttc ttcgtcacgc
    16141 cgagcgtcac cccgcccgcc gtctcgccga agatgccctc ggtgcgggcc agcagcttga
    16201 tcgcgtcgac gacctgctcg tcggtgacgt cctccaccgc gccgccggtg cgccgggcga
    16261 tgtcgaggac gtaggggccg tcggccgggt tgccgatggc cagcgacttg gcgatggtgt
    16321 tcggcttctg gggccgcacg acgtcgtgcc cgcccttgaa ggcggcggag accggggagc
    16381 agccctcggc ctgggcgccg aagaccttgt acggcttgtc ctcgaccaga ccgagcttga
    16441 tcagctcctg gagccccttg tcgatcttcg tgagctgcga gccggacgcg atcgggatga
    16501 cgatctggtc gggcagccgc cagccgagct gctcgcagat ctcgtacgcc agcgtcttgg
    16561 agccctcgcc gtagtacggg cggaggttga cgttgacgaa gccccagccc tcgccgaggg
    16621 ggtcgccgat cagctcggag cagaagcggt tgacgtcgtc gtaattgccc tcgatgccga
    16681 ccagttcacc gccgtacacc gcggccatga cgaccttgcc ctgctccagg tcgtgcggga
    16741 tgaacacgca ggagcgcagt ccggcgcggg cggcggcggc gccgacggcc ccggccaggt
    16801 tgcccgtgga ggagcaggag agggtggtga aaccgaaggc gcgggcggcc tcgacggcga
    16861 tcgcgacgac gcggtccttg aaggagtgcg tcgggttgcc ggagtcgtcc ttcacgtaca
    16921 ggccgccggt gacgcccagc tcacgggcga ggttgtcggc cttgaccagc ttggtgaagc
    16981 cggggttcag gttgggcttg tccgcgacgt cggcggggac gggcagcagc ggggcatagc
    17041 gccagatgtt gtccggaccg gcctcgatgc gcttgcgcag ttcctcggcg gagccggtgg
    17101 gcaggtcgta ggccacttcg agggggccga aacaggacgc acaggcgaag agggggccga
    17161 gctcgaaacg ctcgccgcac tcgcggcagg aaagcgccgc ggcgggaccg aggtccacgg
    17221 gggcggtggt ggcattacct gcaatggtct gaacagccat gatggcggag gccctttctc
    17281 ctcatcttcc tcgcgacgca tttcgccgca agacggaatt ggcaccttcc ccaccgtgac
    17341 ctcgcggtcg gcaggagggt tgccgggact tcaacgggcc gttccctcag tccctctgga
    17401 tgagctctat ggcgctggat cttcgatcca ggcgtttatg tgcgctccga ccccgacatg
    17461 cgacggtcat ccgcgttgtt caagactgta accgaagcac cggaccgttg agatagtcgt
    17521 ccgaaccgcg agatggatca cacacaggga gtgccgaccg tgctcgaaga ggtggaacgc
    17581 tggctgacca ggcgttcctg gtcgtccggc gaccgcccgc tcaaccggct caccgacgcc
    17641 cgggccgccg acccgcgccg tacgtccgtg agcgtggtcc tgcccgcgct gaacgaggag
    17701 gccacggtcg gcgcgatcgt ggcgacgatc cgccgcgagc tgatggagaa gatccggctg
    17761 gtcgacgagc tcgtggtgat cgactccgga tccaccgacg ccaccgcggc ggtggcccgg
    17821 gcggcgggcg cgcgcgtggt ccaccgggac acgatcctgc cccggatccc ggccgtgccc
    17881 ggcaagggcg aggtgctgtg gcgctcactc ctggtgacca gcggggagat cgtctgcttc
    17941 gtggacgccg acctcaagga cttctcggcg gacttcgtct cgggcacggt cggcccgctg
    18001 ctcaccgatc ccacggtcca gttcgtcaag gcgatgtacg accgcccgct cggcggcagc
    18061 gcaggtcagg gcggccgggt cactgaactg gtggcacgcc cgctgctcaa tctgcactgg
    18121 ccgcagctgg ccggtttcgt acagccgctg ggcggcgagt acgcggtgcg gcggtccctg
    18181 ctggagcggc tgccgttccc ggtcggttac ggagtggagc tggggctgct cgtggacgcg
    18241 ctgcacacgg tgggcctgga cgcgctgggc caggtcgacg tcggtgtacg cgtccaccgc
    18301 caccaggacg gtcaggcgct gggccggatg gcggcggcga tctaccgcac ggcccagctg
    18361 cggctctccc ggggccacct ggtgcggccg gtgctgaccc agttcgagcg cggcgaggag
    18421 ggcttcgtac cgcgcaccca tgcggtggac acggaggagc ggccgccgat gcgggagatc
    18481 gcggagtacg cggagcgcca cgcggcgtga gcgggcgagg ggcggccgtc cggggcggac
    18541 ccgcggcgtg gggcggcggg acgcgtgccc ccgcgagcgg gacgcgtgcc cctgcgaggc
    18601 gtttgacggc ttcccgaacg ggctaggttc cgctacatgg tctccgagca cacgtcttcc
    18661 tcgcatgccc aggtcctcgt cgcgtccaac cgcggcccga tcacgtacac actcgacgag
    18721 gacgggacgc tggactccaa gcgcggcggc ggcggcctcg tctccgggct gagcgccgtc
    18781 gacgacaagc tgtgggtgtg cgccgcgctg ggtgacggtg accgcgaggc ggtacgccgc
    18841 ggggtcggcg agccgggcgt gcggatgctg gacatcgacg ccgaggtgca cgccgacgcg
    18901 tacaacggca tcgccaactc cgtgctgtgg ttcgtccacc acctgctgta ccagacaccc
    18961 gtcgagccgg tcttcgacac ggagttccgg cggcagtggg ccgcgtacga ggcgtacaac
    19021 cgggccttcg cccaggcgct cgccgaggag gccgggccgg aagcggcggt cctggtccag
    19081 gactaccacc tggccctggt ccccggcatg ctccgcgagc tgcgcccgga cctgaggatc
    19141 ggccacttct cgcacacccc gtgggccccg gtggactact tccggctgct gcccgacgac
    19201 atcgccgagc agctgctgcg cggcatcctc ggcgcggacc gggccgcgtt cctgacccgc
    19261 cgctggtcgg acgcgttcat cggctgctgt acggagatcc tcggcggcac gggccgcacc
    19321 aggatcgggg tgcacggcct cggggccgac gcggacttcc tgcgccgccg ctcccacgag
    19381 gcggacgtgg acgagcggat ggcggcgctg cgcgagcagg tcggcgagaa caggaagacg
    19441 atcgtgcggg tggaccgcac ggagctgtcc aagaacatcg tgcgcggcct gcacgcgtac
    19501 cggacgctgc tggagacccg ccccgagtgg cgcgagcgcg tcgtccacat cgccttcgcc
    19561 tacccctccc gccaggacct ctccgtctac cgggactaca cggcggcggt ccagtcactg
    19621 gccacggaga tcaacggggc gtacggcacg gatggttgga cgccggtcgt gctccacgtc
    19681 aaggacgact tcgcccgctc gctggccgcg taccgactgg cggacgtggc cctggtcaac
    19741 ccgatccgcg acggtatgaa cctggtcgcc aaggaggtcc cggtcgtctc ggaccacggc
    19801 tgcgccctgg tgctgtcgcg ggaggcgggg gcgtacgagg agctgggcga ggacgcgatc
    19861 gtggtgaacc cgtacgacgt gacgggcacg gcggaggccc tgcacgaagc gctgacgatg
    19921 agcgtcgacg agcggtcggg ccgcacgaag cggctcgcgg aggcggcgac cgcgctcccg
    19981 ccgcagcggt ggttcctgga ccagctggag gcgctgcggc aggagtgaga cccctcgcgg
    20041 cttcacacag ccgctcggcc agggccgccg cccggtcgtg tctacaggcg gtccgccagg
    20101 gccgccagga agtccaccac cgcggcgggg cccggcaccg acaggtcggc ccgctcggcc
    20161 agttcgggca cctcggcgct gccgctgcac accaggaggc cggggacacc gtccgggccc
    20221 tcgccgcgca gcttctccac cgcggcgaac gcggcgaggt ccccgaggtc gtcgcccgcg
    20281 tagatcacgg actccgcgtc cagctccgcg acgaacccgg cgagcgcgac gcccttgtcc
    20341 atgccgggcg ggcgcaactc cagcaccagc cgacccggtt cgacgatcag cccgtgcttg
    20401 gcggccagct cgccgagggg cccgcgcagc gactcgaagg ccgcctgcgg gtcctgcgcc
    20461 cgccgggtgt ggacggcgag ggcctgcccc ttctcctcga tccaggtgcc gttccaggcc
    20521 ccgacgtcgt ggagtacgcc cgggagttcg gcgcgcaccg ccgtgacgcc cggatgcggg
    20581 gcgggggcgc ggaccgtgcc ggtcacggcg tcccagcgct cggccccgta atgtccgagc
    20641 acgacgaggc gctccaggcc ggggacgccc gcgaagccgc cgtagcgcac ggcgacgccc
    20701 gccgggcggc cggtgatcac ggcgatcgcg gcgaccttcg gcgcgagcgc ggcgagcgcg
    20761 gcgacggtgc cggggtgggc gcgggcctgc tcggggtccg ggacgatgtc ggcgagcgtg
    20821 ccgtcgaagt cgagggcgac gaccgcgcgg tcgggccggg ccagaacggc gtcgagcccc
    20881 tcgcggccgg ccggggtggt cgggttcgga agacgttccg ggtgactgcc catggggcga
    20941 gcctaagccc tcgaccggtc gaccacgagc cctgccccgg gcggaacgcc ccctactcgg
    21001 gggagcccgc cagctcgacc ggccggggcc gcagcgcgga cagggccggc aggacggcgg
    21061 agccggcggc caggagcgcg gcggccgcga cgacgaggcc gagcgttccc cagggcacca
    21121 cgacggcggt cgtgacgccc agcagcgcca gcgcgcccca cacgaccagc aggttcaccg
    21181 cggcgaccag gcccccgagc accgcgccca ccccgaccgc cgccaccgcc tcggccacga
    21241 cgagccgcag gacctgcggg acggtggccc cggcgagtcg gagcacggcg aggtcgcgcc
    21301 cccggtggga ggtggccatc accagggtgt tggccagggc ggtcccggtg gcgagcagag
    21361 cgatgccgag gatcatgcgc agaccggtgc gcgtggggtc gtccgggccg agggcggccg
    21421 cgggcggatc gtcagcgggg cgggcatccg gccccggacc ggtcggggcc ggccgctccg
    21481 cgggggtctc cacccgcgta ccggtgtcgg cagcggcggt gttcagcgcg gcggcgacgg
    21541 cgcgccggtc gccgcccgga gcgaccttga cgtcgatccg gtcgatctcc gcgcccccgg
    21601 cattgcgcgc ggtg
//
