LOCUS       NZ_BMSZ01000010        21053 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces badius strain JCM 4350 sequence10, whole genome shotgun
            sequence.
ACCESSION   NZ_BMSZ01000010
VERSION     NZ_BMSZ01000010.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces badius
  ORGANISM  Streptomyces badius
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 292234)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: BGI assembly pipeline
            Genome Coverage                   :: 154X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014649415.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 03:57:07
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,894
            CDSs (total)                      :: 6,825
            Genes (coding)                    :: 6,582
            CDSs (with protein)               :: 6,582
            Genes (RNA)                       :: 69
            rRNAs                             :: 2 (23S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 244
            CDSs (without protein)            :: 243
            Pseudo Genes (ambiguous residues) :: 0 of 244
            Pseudo Genes (frameshifted)       :: 70 of 244
            Pseudo Genes (incomplete)         :: 206 of 244
            Pseudo Genes (internal stop)      :: 7 of 244
            Pseudo Genes (multiple problems)  :: 38 of 244
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:11:55
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 223343
            Orig. end                         :: 244396
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMSZ01000010.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21053
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="4"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21053
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21053
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11053](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11053
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(359..1462)
                     /locus_tag="IE135_RS18845"
                     /old_locus_tag="GCM10010253_38050"
     CDS             complement(359..1462)
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007455231.1"
                     /locus_tag="IE135_RS18845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_38050"
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /protein_id="WP_069735217.1"
                     /transl_table=11
                     /translation="MVRQRRAKWIPLGVIVLGVVLDLVTPADVTSAPLLMAAPVAAAPL
                     LGLRGIIAIGALAMAVHAVLAWYDGTFGWQRGVANQLTLVAVTVLAVLINRSLEGRDAR
                     TRRARHIAAVAQSAVLPRPPSRLGELRIAARYVPAEDEAMIGGDLYVVQDTPHGVRVMV
                     GDVRGKGLGAVSAVCADLGAFRYAADEAEDLPGLVAALERALLREGGRRGGQDQDEGFT
                     TALIAEFADDLGTVRVVNRGHPPPVLLDARGRATVLEPSEEAPPLGMSGLGTWSCPVDT
                     FPFPPGATLICYTDGVTEARDESGVFYDASVRLPFLVHHRALVGYPASPAQILHLLIED
                     VGHHTGGRIQDDQALLALHRPPAPPHA"
     gene            complement(1523..2356)
                     /locus_tag="IE135_RS18850"
                     /old_locus_tag="GCM10010253_38060"
     CDS             complement(1523..2356)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012382057.1"
                     /locus_tag="IE135_RS18850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_38060"
                     /product="Scr1 family TA system antitoxin-like
                     transcriptional regulator"
                     /protein_id="WP_069735275.1"
                     /transl_table=11
                     /translation="MRARSGPTVEHRVLAVRLRMLRERAGVSLRAAAEALDAHPATVRR
                     IERAETGLDARQVGELLRCYGVPPAVAEPIMAGLAAANLPGWWHRWRDTMEAWQQEVIG
                     VESSASLVRTWHPALVPELLRTPAYAAALHRTQYPEDSPARRERRVELLRERRRRLCER
                     GATLWALFPAAALHTRVGDRATMEGQRAALAEAMKEQHVTVQVVPLDHPPHPLTGVPPL
                     HILRVPAPEIGDQAVLETPGVRVDLIDDPEAVTAHRIRLDAACAAAPGPGAPLPE"
     misc_feature    2317..2331
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.64"
                     /tool="antismash"
     misc_feature    complement(2519..2533)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.35"
                     /tool="antismash"
     gene            2588..2953
                     /locus_tag="IE135_RS18855"
                     /old_locus_tag="GCM10010253_38070"
     CDS             2588..2953
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012382056.1"
                     /locus_tag="IE135_RS18855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_38070"
                     /product="ATP-binding protein"
                     /protein_id="WP_069735276.1"
                     /transl_table=11
                     /translation="MRAWGEPAERIEAAALIATELVTNAVQHTSTRRIRCRLLRSAGGV
                     RICVWNRGRARIPAPASPADSAGLPVGQVPAAADLEGDPALARLPEDGRGLLLVDALAA
                     RWGTRAALAGRLVWADL"
     gene            complement(2981..3694)
                     /locus_tag="IE135_RS18860"
                     /old_locus_tag="GCM10010253_38080"
     CDS             complement(2981..3694)
                     /EC_number="3.1.26.4"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012382055.1"
                     /locus_tag="IE135_RS18860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_38080"
                     /product="ribonuclease H"
                     /protein_id="WP_199888615.1"
                     /transl_table=11
                     /translation="MNESIIAACDGASKSNPGPAAWAWVVADAQGEPVRWEAGPLGAAT
                     NNVAELTALAQLLESTDPAVPVEVRMDSQYAMNAVTKWLPGWKRNGWKTSGGKPVANRE
                     LVTRIDALLADRSVTFRYVPAHQVNGDPLNAIADQAASEVAVTQLPAGTAHGATALPVP
                     APARSTKGRTEASGASGGSKGRGAGGASRSGRSGGTIKARFAGRCHCGKPYAAQEPIAK
                     NPNGWGHPECRTVPA"
     gene            3910..5808
                     /locus_tag="IE135_RS18865"
                     /old_locus_tag="GCM10010253_38090"
     CDS             3910..5808
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) ABC_efflux"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061756.1"
                     /locus_tag="IE135_RS18865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_38090"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_199888616.1"
                     /transl_table=11
                     /translation="MDMEVTAWHSLHSAMNAQQDRRPFSRASLRRIMLFARPHRRRIHR
                     FLLLSVLTALLAVATPLLAGKVVDTIVSGEDTGAVTRLALLIALIAVVEAGLGLLTRWL
                     SATLGEGLILDLRTAVFDHVQKMPVAFFTRTRTGALVSRLNNDVIGAQRAFSNTLSGVV
                     SNLVTLLLTLAVMLTISWQITLLSLVLLPVFVVPARRMGARMAGLQREAADHNAAMGTQ
                     MTERFSAPGATLVKLFGRPSDESAEFAARADRVRDIGVRTAMAQSAFITALTLVSALAL
                     ALVYGLGGFYALRGSLDPGAVVALALLLTRLYAPLTALAGARVEVMSALVSFERVFEIL
                     DLKPLIEQKPDARRVPEGPVSVEFDEVSFGYPTAEKVSLASLEEVATLDDRGGTPVLHQ
                     VSFRAEPGQTIALVGSSGAGKSTIAQLLPRLYDADAGSVRLNGVDVRDLSADSIRDTLG
                     MVTQDGHLFHESVRANLLIARPDASEAEIWDALRRSRLDGLIASLPDGLDTVVGERGYR
                     LSGGERQRLTIARLLLARQRVVILDEATAHLDSTSEAAVQEALAEALSGRTALVIAHRL
                     STVRAADRILVLEAGRVVESGTHAELLTAGGRYEELYRTQFERPSSDGERPVQPVG"
     misc_feature    complement(3911..3925)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.77"
                     /tool="antismash"
     assembly_gap    5836..5877
                     /estimated_length=42
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<5878..6092)
                     /locus_tag="IE135_RS18870"
     CDS             complement(<5878..6092)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018514850.1"
                     /locus_tag="IE135_RS18870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_199888643.1"
                     /transl_table=11
                     /translation="MTTEAPRRPRIEHVTTAGSALAVTLLPLVVGVLLAKTLAADPMTS
                     VNALVTNGHRPRVSPKEWRRCGGHALR"
     gene            6245..6898
                     /locus_tag="IE135_RS18875"
                     /old_locus_tag="GCM10010253_38110"
     CDS             6245..6898
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010069847.1"
                     /locus_tag="IE135_RS18875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_38110"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_199888617.1"
                     /sec_met_domain="PCMT (E-value: 6.7e-06, bitscore: 20.1,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDSQGRAGEGHGSEAAAVFDALGAEYERAFAASAAHRQSLERLL
                     AGLAPGSSVLDVGSGTGRPTAQTLADAGHRVLGVDVSPVMTALAARQVPGAEFRCADIR
                     DLPLAEGEFDAVCVYFSLLQLERGEQSDLLERLVRSLRPGGLLAAATVPVDVAGVDAVF
                     MGQPVRVSSFGAEEFTALTARAGVAVEWTHSALFTPDHPAGEPEPHLFVHGRRI"
     misc_feature    complement(7124..7139)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.96"
                     /tool="antismash"
     misc_feature    complement(7152..7172)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.75"
                     /tool="antismash"
     gene            7216..7812
                     /locus_tag="IE135_RS18880"
                     /old_locus_tag="GCM10010253_38120"
     CDS             7216..7812
                     /GO_function="GO:0004089 - carbonate dehydratase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010069848.1"
                     /locus_tag="IE135_RS18880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_38120"
                     /product="carbonic anhydrase"
                     /protein_id="WP_069735222.1"
                     /transl_table=11
                     /translation="MQSLVEHARTFTEHVAANAKDFERFADGQTPEALFVTCSDSRVVP
                     SLITGARPGQLFELRTAGNIVPPYPGRDRPTGEAATIEYALCVLQVRDIIVCGHSHCGA
                     VGAILRGDDLSAMPAVRHWLERSTDGRTPPDDAGDLPGAVQAHALAQLDTLRGYPAVRE
                     RLAEGSLGLHAWYYEVHTGSVSVHRPERGTEFARL"
     gene            7885..9354
                     /locus_tag="IE135_RS18885"
                     /old_locus_tag="GCM10010253_38130"
     CDS             7885..9354
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015103 - inorganic anion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003970902.1"
                     /locus_tag="IE135_RS18885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_38130"
                     /product="SulP family inorganic anion transporter"
                     /protein_id="WP_199888618.1"
                     /transl_table=11
                     /translation="MISAKELKNPHVVRRDLLASLVVFLVALPLCVGVAVASGVPAELG
                     LVTGIVGGLVVGLLPGSKLQVSGPAAGLTVLVFEAVKEFGLSTLGPIVLAAGLLQVVLG
                     LARFGRWFRAISVSVVQGMLAGIGLIIVLGQVYAMADLEQPGSGLAKLAGLPGLAADIV
                     TNQEALTAFGLGAGTVAMLLLWPKLPARVRIVPAPLAAVALATAVASLAGLRPAVADVN
                     GLLNAIDLPGGAEFSRLADVAVIGTVLAFALIASAESLFSAAAIDRMHDGPRTDYDKEL
                     VAQGVGNTLCGALGALPMTAVIVRSAANVQAGATTALSRVAHGLWLLLFAALLPAAVGI
                     IPLAALAGVLVHAGCKLVPAKEFGPLWREHRGEAVLLAITAIAIVVTNLFEGVVLGLLL
                     AVVKSAWETSHVQLTTHELTGGRVVVTLTGNATFLRLPRILEQLEKLPQDQPIELDLTG
                     LRHLDHACRVALENWARRHNNAEIEPVTIRQ"
     gene            9730..10008
                     /locus_tag="IE135_RS18890"
                     /old_locus_tag="GCM10010253_38140"
     CDS             9730..10008
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007379395.1"
                     /locus_tag="IE135_RS18890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_38140"
                     /product="polyprenyl synthetase"
                     /protein_id="WP_069735224.1"
                     /transl_table=11
                     /translation="MTSESGHGETLDERAVLLVAGAADLAVSAIGSALGAVRGLLRRSD
                     TAELAAEAEHELKARGRLVLDRYAAPPPAHLEILARQAVARRSTEDV"
     gene            10001..11053
                     /locus_tag="IE135_RS18895"
                     /old_locus_tag="GCM10010253_38150"
     CDS             10001..11053
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031263.1"
                     /locus_tag="IE135_RS18895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_38150"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_199888619.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4e-37, bitscore:
                     121.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDRWDAAAFKTRVDEVLHQFVAREVDLFAKIDPSLAPVAAQLEA
                     AVQDGKRLRAAFCYWGWRAVGQPDSSALLRAAASLELIHAAAVVHDDLIDDSALRHGRP
                     TAHVALRGAVRRRPRSAAAARSLAMLVGDLLMGMAGQLFATSGLPAAYVGRARPLWSVL
                     GRELIAGECLEILRTGSEPDTDASLQVIRYKTAKYTVEQPLLIGGALAGAGGRLREGYS
                     AYGLPLGEAFQLRDDLLGLFGDPEHTGKANADDVRGQRPTALLAETWRIAGEDDRTRLR
                     ALLGQRGLDEAGLQAVREVMCRLRSPSLVEDMITARVEEALGALGDLDLPAGPADALGA
                     LANSATVRLF"
     gene            11097..12260
                     /locus_tag="IE135_RS18900"
                     /old_locus_tag="GCM10010253_38160"
     CDS             11097..12260
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240938.1"
                     /locus_tag="IE135_RS18900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_38160"
                     /product="oxygenase MpaB family protein"
                     /protein_id="WP_069735226.1"
                     /transl_table=11
                     /translation="MNYTEASMNVLRQGGDELADATVAALFERGEVGKFNTLMRHVSTT
                     GTPLPDGLPDVAREYLRTTSAPPDWVDWELMEKARLFFIDNNVHISTALSFASMPACYV
                     VPHVARLLSATHGLRYPSKRMAETGQFTVYLMQPDAFEAGGRFIPAAQKVRLLHASIRH
                     HLQRENRWDTSALGTPICQEDMIGGQMFFSLLVLDSLHRLGIHMSTEGAEAYYYAWRVV
                     GAMLGVDQQAVPPTLDDARAFLDLYMVRHMGPSEEGALLTRQLIDLYEEVVPGTLFDPV
                     VSALIRHLIGDTCADWLRVPRSSWDTAVKAVPHLLGLLETIEDRSPLGARALDHLGRLT
                     TLLELSSLTRGRVMHYAIPEQLKDAYGVTPASHRARRWNPPAATSSS"
     misc_feature    12350..12365
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.41"
                     /tool="antismash"
     misc_feature    12371..12386
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.46"
                     /tool="antismash"
     gene            12611..>13581
                     /locus_tag="IE135_RS34405"
                     /old_locus_tag="GCM10010253_38170"
     CDS             12611..>13581
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010062579.1"
                     /locus_tag="IE135_RS34405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_38170"
                     /product="cellulose binding domain-containing protein"
                     /protein_id="WP_234427967.1"
                     /transl_table=11
                     /translation="MVGLATPAQAAASATATYTKASDWGSGFEGKWTVKNTGTTTLSAW
                     TVEWDFPANTKVTSAWDATVTNSANHWTAKNLGWNGTLAPGASVSFGFNGSGSGAPSGC
                     KLNGNPCDGGSTNPGDNAPSAPGKPTASDITNSSVKLSWAAATDDKGIKNYDVKRDGAT
                     VATVTGTTYTNTGLTAGTDYSYSVVARDTADQTGPASAATTVRTTGGGGGGENPGGNGK
                     INLGYFTNWGSYTVKNLVTSGSAEKITHINYAFGNVQNGKCTIGDAYEDYEKSYTAAQS
                     VDGKADAWDQPLRGHFNQLRKLKAQYPHIKILWSFGGWTWSGG"
     assembly_gap    13582..13628
                     /estimated_length=47
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <13629..14292
                     /locus_tag="IE135_RS34410"
                     /old_locus_tag="GCM10010253_38180"
     CDS             <13631..14292
                     /codon_start=2
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004925477.1"
                     /locus_tag="IE135_RS34410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_38180"
                     /product="glycoside hydrolase family 18 protein"
                     /protein_id="WP_234427960.1"
                     /transl_table=11
                     /translation="GLTCDTSGPAAFKNMMQAMRAEFGPDNLLTAAITADGSNGGKLDA
                     ADYGGAAPYINWYDVMTYDYFGSWAAQGPTAPHSPLTSYPGIPAQGFNSADAIAKLKAK
                     GVPASKLLLGIGFYGRGWTGVTQSAPGGTATGPAAGIEPGNQYYKVLKTSCPATGTVGG
                     TAYAHCGNDWWSYDTPATVGTKMAWAKSQGLGGAFFWEFNGDTANGELVTAINSGLK"
     gene            complement(14456..14893)
                     /locus_tag="IE135_RS18910"
                     /old_locus_tag="GCM10010253_38190"
     CDS             complement(14456..14893)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956703.1"
                     /locus_tag="IE135_RS18910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_38190"
                     /product="DUF2267 domain-containing protein"
                     /protein_id="WP_069735228.1"
                     /transl_table=11
                     /translation="MTHEPRNAGAPMDTTFGLLLEKIRYEGAYPTRERAEESLCAVLGA
                     LGRQITGDERVALAAALPEEAARVFTAEVPAVKQLAGAAFVAELAERTGGTPATARWDA
                     GVVLSQIAALVGDDLVAEVVSCLPPGYALLFGRAELLAQAA"
     gene            complement(14998..15396)
                     /locus_tag="IE135_RS18915"
                     /old_locus_tag="GCM10010253_38200"
     CDS             complement(14998..15396)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010069852.1"
                     /locus_tag="IE135_RS18915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_38200"
                     /product="DUF2267 domain-containing protein"
                     /protein_id="WP_069735229.1"
                     /transl_table=11
                     /translation="MTLRWEAFLDRVQERGEYETHGEAERAARVVLALLGAHLVGGERA
                     ELAARLPETMALILLNPLQAAEPLSPERFVRATAAWIEGAGEQTARWDVGAVLSVAAEA
                     AGEDLTRRILLQLPPGYDLLFGGHPKST"
     misc_feature    complement(15358..15371)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.79"
                     /tool="antismash"
     gene            complement(15501..15932)
                     /locus_tag="IE135_RS18920"
                     /old_locus_tag="GCM10010253_38210"
     CDS             complement(15501..15932)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010069853.1"
                     /locus_tag="IE135_RS18920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_38210"
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="WP_069735230.1"
                     /transl_table=11
                     /translation="MLMRTDPFRELDRITEQLLRPGTWSRPSAMPMDAYREGDEYVVAF
                     DLPGVSPDAIDIDVERNMLTVKAERRPAVNADNVQMELSERPLGVFSRQIVLADTLDTE
                     RIDADYEAGVLTLRIPIAERAKPRKIAIGGESRRKQIKG"
     misc_feature    complement(15920..15940)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.99"
                     /tool="antismash"
     gene            16072..16755
                     /locus_tag="IE135_RS18925"
                     /old_locus_tag="GCM10010253_38220"
     CDS             16072..16755
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010069854.1"
                     /locus_tag="IE135_RS18925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_38220"
                     /product="HSP18 transcriptional regulator"
                     /protein_id="WP_069735231.1"
                     /transl_table=11
                     /translation="MTPPTQPEPPRRSTPDAVSFLAAWAALQTIDEAVRDAHGHAGDAT
                     SGPPPATERAEALASLQLLREVREQLAGWETGLIETARAAGASWADLADPLGVASRQAA
                     ERRYLRLRPGSEGSTGEQRVRATRDRRAGDRSITAWARQHAADLRSLAGRIAALTDLPA
                     AADAPLDRLRQALGTDDAAALVTPLTALHPHLAPGHGELADRVDALTQHTGRLREDTAA
                     RRRGD"
     gene            complement(16849..17634)
                     /locus_tag="IE135_RS18930"
                     /old_locus_tag="GCM10010253_38230"
     CDS             complement(16849..17634)
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606939.1"
                     /locus_tag="IE135_RS18930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_38230"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_069742031.1"
                     /transl_table=11
                     /translation="MSADDDEFRRSIRSDVPHSARVWNAWLGGKDHYPVDRELAEAVSA
                     AYPQMADIARASRAFQIRAIRHLVSVGVRQFLDVGTGLPVANSTHEVAQSIAPESRVVY
                     VDNDPIVLAHAEALLTGAPEGRTAYVDADLSATDVVVDEAAKTLDLSEPVAVLLLSTLG
                     HLVPAEGIEVVQRYLARMPSGSHLVLCDTVKTPQTLAAQEAYASGDNPPYLVREPAEIT
                     GCAEGLELVEPGFVPIDRWRPEEEDAVPVDQWGLVARKP"
     gene            complement(17762..17917)
                     /locus_tag="IE135_RS18935"
                     /old_locus_tag="GCM10010253_38240"
     CDS             complement(17762..17917)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061771.1"
                     /locus_tag="IE135_RS18935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_38240"
                     /product="hypothetical protein"
                     /protein_id="WP_164873471.1"
                     /transl_table=11
                     /translation="MDLFDGELGGRDDRGLDTGGGWSWCGVITVGIFILLAVLISWIFG
                     LVGRLF"
     gene            18102..18308
                     /locus_tag="IE135_RS18940"
                     /old_locus_tag="GCM10010253_38250"
     CDS             18102..18308
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE135_RS18940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010253_38250"
                     /product="hypothetical protein"
                     /protein_id="WP_199888620.1"
                     /transl_table=11
                     /translation="MHNGNHVRAEAPWNCSTLPPYGGAKTKVNLYRDGVLVKSAEFRPN
                     GLLNARYGRARPSPSVRSDTRTG"
     gene            18399..19859
                     /locus_tag="IE135_RS18945"
                     /old_locus_tag="GCM10010253_38260"
     CDS             18399..19859
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010069857.1"
                     /locus_tag="IE135_RS18945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_38260"
                     /product="dienelactone hydrolase family protein"
                     /protein_id="WP_199888621.1"
                     /transl_table=11
                     /translation="MTEPTAGLPLSAPEALTVLGALVLVLARWLPDRLRGPAALAAGAL
                     LAGSVTVLVATGTRWQLVPVLVVAAVAGGFALAPLLARRSGRTPWRARWWLAVPGSVVC
                     AALVATGPVSAWAFPVPDFPAPSGRFPVGTETVEWSVPATRSEREKRPRVAGPRPLVVQ
                     LWYPAGRSAPEARRAPYLGRTEAEARTVSAALADYAGVPGFLLDGLPRARSHAVPGAPV
                     ANGGGRFPVVLFSPGLGGARTQNTAWAEELASHGYVVAAVDHPYDSAAVVLSDGRTLRT
                     RVTATGDRAKDRALAEKWTRTRAADLRAMLTRLERLERGGAEGRLAGRLDVGRVAAAGH
                     SIGGAAALRAARQDPRFDAVVDLDGFPHGPVGGRFEQPVLALTQEIGRGTDPDYLPRLT
                     RVLERSDATSYRLTVPGAAHLTFTDAPLYLPPVPGIVGSLGRTEGHRITAGATLSFLDA
                     TLRRAPVDVPAALSAHGEVTVHRPEGAR"
     CDS             complement(20005..>20734)
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=3
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012382041.1"
                     /locus_tag="IE135_RS34415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="WP_308432632.1"
                     /sec_met_domain="LANC_like (E-value: 1.5e-40, bitscore:
                     133.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="ADDITRHGSRLPAWWITDGLDHGLPEHVNLGLAHGVPGPLALLAL
                     AWRAGVRVDRQDEAIERTMALLTSLRTFDEAGPRWPHLMSRERIEKGEPPERGRDSWCY
                     GAAGAARAVHLAGSALDRPEWRADAEAALRGALAVASDESIRDSALCHGWAGLLQIVLR
                     TAEDTDDPELHATADRLAARVLDGFDPGAPFGFRYAHALAHRPLDRPGFLEGAAGIALA
                     LHTYAIGRAPVTSWDSALLLS"
     gene            complement(20005..>20738)
                     /locus_tag="IE135_RS34415"
     assembly_gap    20739..20786
                     /estimated_length=48
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     misc_feature    20892..20906
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.54"
                     /tool="antismash"
ORIGIN
        1 ttcagggcgc gccgctcgtt ctcggacagg ccgccccaga tgccggagtc ctggccgttc
       61 tccagggccc actccaggca ggcggcctgg acggggcagg tccggcagac ggccttcgcc
      121 tcctcggtct ggacgaccgc ggggcccgtg ctcccgatgg ggaagaacag gtccgggtcc
      181 tcctcgcggc aggcggcgtg caagcgccag ttctcggtgc tgctcaactc tgctcactcc
      241 cgaatgtcgt gacgtcgtcg gtgtgttgcc gtacgtgtct tccgtgcggg tgaccgacga
      301 tcgacgcctc aaacacgtat cgggcgggca ggtcccggag ccggaagcgc agggcccgct
      361 acgcgtgcgg aggggcaggc gggcggtgca gcgcgaggag ggcctgatcg tcctggatcc
      421 ggcccccggt gtgatggccg acgtcctcga tcagcagatg gaggatctgc gccggggagg
      481 ccgggtagcc gaccagcgcg cggtggtgga cgaggaaggg cagccggacg gacgcgtcgt
      541 agaagacccc ggactcgtcg cgcgcctcgg tgaccccgtc cgtgtagcag atgagggtgg
      601 cgccgggcgg aaacgggaac gtgtcgaccg ggcacgacca ggtccccagg ccgctcatgc
      661 cgagcggggg cgcctcctcg gagggttcga ggacggtggc ccggccccgg gcgtccagga
      721 gcaccggcgg aggatgcccg cgattgacga cccgtacggt accgaggtcg tcggcgaact
      781 cggcgatcag cgcggtggtg aacccctcgt cctgatcctg gccgccgcgc ctgccgccct
      841 cgcgcagcag ggcccgctcc agcgcggcga ccaggccggg caggtcctcc gcctcgtccg
      901 ccgcgtaccg gaaggccccc aggtccgcgc agaccgcgct gaccgcgccc aggcccttgc
      961 cgcgcacgtc cccgaccatc acgcgcaccc cgtgcggggt gtcctggacg acgtagaggt
     1021 cgccgccgat catggcctcg tcctcggcgg gcacgtaccg ggcggcgatc cggagctccc
     1081 cgaggcgcga agggggccgg ggcaggacgg cgctctgggc cacggcggcg atatggcggg
     1141 cgcgccgggt ccgggcgtcc cggccctcca gggaacggtt gatgaggacg gccagcacgg
     1201 ttacggccac aagggtgagc tggttggcga cgccgcgctg ccagccgaag gtgccgtcgt
     1261 accacgcgag gaccgcgtgg acggccatgg cgagcgcccc gatcgcgatg atgccgcgca
     1321 ggccgagcag cggcgcggcg gcgaccgggg ccgccatcag caggggcgcc gaggtgacat
     1381 ccgccggggt caccaggtcc agcacgacgc ccagcacgat gacccccagc gggatccact
     1441 tggccctgcg ctgccgcacc actcccccac gctgcacggg actggagccc gccgcatccc
     1501 ggcgggcttc ggccggacac ggtcactccg gcagcggggc cccggggccg ggcgcggcgg
     1561 cgcacgcggc gtcgagccgg atgcggtggg ccgtcacggc ctcggggtcg tcgatgaggt
     1621 cgacccgcac gcccggggtc tccagcaccg cctggtcccc gatctcgggt gcgggcaccc
     1681 ggaggatgtg caggggcggg acgccggtca gagggtgcgg cgggtggtcg aggggcacca
     1741 cctggacggt gacgtgctgc tccttcatcg cctcggccag cgcggcccgc tgcccctcca
     1801 tggtcgcccg gtcgccgacc cgcgtatgaa gggccgcggc cgggaacagg gcccacaggg
     1861 tggccccgcg ctcgcacagc cggcggcggc gttcgcgcag cagctcgacc cggcgttccc
     1921 gccgggcggg gctgtcttcg gggtactgcg tgcggtggag ggcggcggcg tacgcggggg
     1981 tgcgcagcag ttcgggcacg agcgccgggt gccaggtccg cacgaggctc gccgaggact
     2041 ccacgccgat gacctcctgc tgccaggcct ccatcgtgtc ccgccagcgg tgccaccagc
     2101 cgggcaggtt cgcggccgcg agcccggcca tgatgggttc ggccacggcg ggcggcacgc
     2161 cgtagcagcg cagcagttcg ccgacctgcc gggcgtcgag tccggtctcc gcgcgttcga
     2221 tgcgccgtac ggtggcgggg tgggcgtcca gtgcctcggc ggcggcccgc aggctgacgc
     2281 ccgcgcgttc ccgcagcatg cggaggcgga ccgcgaggac gcggtgttcc acggtggggc
     2341 cggaccgggc tctcatgcgc ataccttttt cgtccagccc cgtggcggag catgacacac
     2401 tctgtcgctt gcaaagtatg cgttttgcgt cgagagtgca tacatgtcgg aaatagtcag
     2461 ttgcgcggag cgtgcccccg atgacggagg tgtccaaggt gccgaaggca cccgaagtgc
     2521 acacagctgg tgggtccccc gattgccagg tggcgtgccg gaggcccggc accgggtcca
     2581 ggaggccatg cgggcctggg gcgaaccggc cgagcggatc gaagcggcgg ctctgatagc
     2641 gaccgaactg gtcaccaacg cggtgcagca caccagcacc cggcggatcc gctgccggct
     2701 cctgcgctcc gcggggggcg tgcgcatctg cgtgtggaac cgcggccggg cccggatccc
     2761 ggccccggcc tctccggccg actcggcagg ccttcccgtc ggccaggtcc cggcggcggc
     2821 cgacctcgaa ggcgacccgg cgctcgcccg cctgcccgag gacggcaggg gcctcctgct
     2881 cgtcgacgcg ctggcagccc gctggggcac gcgcgccgcg ctggcgggcc ggctcgtctg
     2941 ggccgacctc tgagactccc ttccccgcct ccccgtccgg tcaggcgggg accgtacggc
     3001 actccgggtg gccccagccg ttcgggttct tcgcgatcgg ctcctgggcc gcgtacggct
     3061 tgccgcagtg gcaccggccc gcgaagcgcg ccttgatcgt gccgccggac cgcccgctcc
     3121 gggacgcgcc cccggccccc ctgcccttcg agccgcccga cgccccggac gcctccgtac
     3181 gccccttcgt ggagcgcgcg ggcgcgggca ccggcagagc cgtcgcgccg tgcgccgtac
     3241 cggccggaag ctgggtgacg gccacctcac tggccgcctg gtcggcgatc gcgttgagcg
     3301 ggtcgccgtt cacctggtgg gccgggacat agcggaacgt caccgagcgg tcggcgagca
     3361 gggcgtcgat gcgggtgacc agctcgcggt tggcgacggg cttgcccccg gaggtcttcc
     3421 agccgttgcg cttccagccc ggcagccact tggtcacggc gttcatggcg tactgcgagt
     3481 ccatccgcac ctcgacgggc accgccggat cggtggactc cagcagctgc gccagagccg
     3541 tcagctcggc cacgttgttg gtcgcggcgc cgagcggacc ggcctcccag cgcacgggct
     3601 cgccctgcgc gtcggccacg acccacgccc aggcggccgg cccggggtta ctcttcgacg
     3661 ccccgtcaca cgcggcgatg atgctctcgt tcatccctcg atcatgccag ccccgcatga
     3721 ccgctccgac cggccgcgcg accggccggc cacgaccccg ccaggctctc cccctgcccc
     3781 cggcacaccg tccgtcttga cctcaagcaa acttcaggtt ctagcgttct cagtgaaccc
     3841 ggggccgcac ggccgacggg gtccgcaggc cgtcgggcga tccgggggcc atcgatatcg
     3901 gagcgcccca tggacatgga agtcacggcg tggcattcgc tgcacagcgc gatgaacgcc
     3961 cagcaggacc gccggccctt ctcccgggcg tccttgcgcc gcatcatgct cttcgcccgc
     4021 ccccaccgac ggcggatcca ccgcttcctg ctgctgagcg tcctcaccgc gctgctcgcg
     4081 gtggcgactc cgctgctggc cgggaaggtc gtcgacacga tcgtcagcgg cgaggacacc
     4141 ggcgcggtca cccggctcgc cctgctcatc gcgctcatcg ccgtcgtcga ggccggcctc
     4201 ggtctgctca cccgctggct gtcggcgacg ctgggcgagg ggctgatcct ggacctgcgc
     4261 accgccgtct tcgaccatgt gcagaagatg ccggtggcct tcttcacccg gacccggacc
     4321 ggcgccctgg tcagcaggct caacaacgac gtgatcggcg cgcagcgggc gttcagcaac
     4381 acgctctccg gagtcgtctc caacctcgtc acgctgctgc tgacactcgc ggtgatgctc
     4441 acgatctcct ggcagatcac cttgctgtcg ctggtgctgc ttccggtgtt cgtcgtaccg
     4501 gcccgccgga tgggagcccg gatggcggga ctccagcggg aggcggccga ccacaacgcc
     4561 gcgatgggca cccagatgac cgagcgcttc tccgcccccg gcgcgacgct cgtcaagctc
     4621 ttcggccggc cctcggacga atcggccgag ttcgccgccc gcgccgaccg ggtgcgtgac
     4681 atcggcgtcc gtacggcgat ggcccagtcg gcgttcatca ccgccctcac cctggtctcc
     4741 gccctggcgc tggccctggt ctacgggctc ggcggcttct acgccctgcg cggcagcctg
     4801 gacccgggcg ccgtggtggc gctggcgctg ctgctgaccc ggctgtacgc gccgctcacc
     4861 gccctcgccg gggcccgggt cgaggtgatg agcgcgctcg tcagcttcga gcgggtcttc
     4921 gaaattctgg acctgaagcc gctgatcgag cagaagccgg acgcccgccg ggtgcccgaa
     4981 gggccggtct ccgtggagtt cgacgaggtg tccttcggct accccaccgc cgagaaggtc
     5041 tccctggcct cgctggagga ggtcgccacg ctcgacgacc ggggcggcac cccggtcctg
     5101 caccaggtgt ccttccgggc cgaaccgggc cagacgatcg ccctggtggg ctcctcgggc
     5161 gcgggcaagt cgacgatcgc gcagttgctg ccccggctgt acgacgcgga cgccggttcc
     5221 gtacggctga acggtgtcga cgtccgcgat ctgagcgccg actcgatccg ggacacgctc
     5281 ggcatggtca cccaggacgg gcacctgttc cacgagtcgg tacgcgccaa cctgctgatc
     5341 gcccggcccg acgcctccga ggccgagatc tgggacgccc tgcgccgctc ccggctggac
     5401 ggtctgatcg cctcgctgcc cgacgggctc gacaccgtgg tcggcgagcg tggctaccgg
     5461 ctctccggcg gggagcgcca gcgcctcacc atcgcccggc tgctgctggc ccgtcagcgg
     5521 gtcgtgatcc tcgacgaggc gaccgcgcac ctcgactcca cctcggaggc ggccgtccag
     5581 gaggcgctgg ccgaggcgct gtcgggccgg accgccctgg tgatcgccca ccggctctcg
     5641 accgtacggg cggccgaccg gatcctggtg ctggaggcgg gccgggtcgt cgagagcggc
     5701 acgcacgcgg agctgctgac ggccggcggc cggtacgagg agctgtaccg cacccagttc
     5761 gagcggccgt catcggacgg ggagcggccg gtccagccgg tcggctgagc cgggttccac
     5821 gcccgtagcg gagtgnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnncgc
     5881 agggcgtggc cgccgcaccg gcgccactcc ttcggcgaga cccgcgggcg gtgcccgttg
     5941 gtgacgagcg cgttcaccga tgtcatcggg tccgccgcca aggtcttggc cagcagcacg
     6001 ccgaccacca gcgggagcag cgtgacggcc agggcggaac cggcggtggt gacgtgctcg
     6061 atacgggggc ggcgcggcgc ttcggtggtc atacggccat cgaacagcgg ccgggtggcc
     6121 cggacaatcg gagaacgtac tcaggagcgc ggggccggca tactcaggcg ctcgccgggg
     6181 gacgctctca gcggccgggc acacggcccc cggccggccg ccggaccacg gaaggaccgc
     6241 ctcgatgggt gacagccagg gacgcgcggg cgagggtcac ggaagtgagg ccgcggcggt
     6301 gttcgacgcg ctcggcgcgg agtacgaacg ggccttcgcc gcttcggccg cccaccggca
     6361 gtcgctggag cggctgctgg ccggcctggc cccgggcagc agcgtgctgg atgtgggcag
     6421 cgggacgggc cggccgacgg cacagaccct ggcggacgcg ggccaccggg tgctgggcgt
     6481 cgacgtgtcg ccggtgatga ccgcactggc ggcccggcag gtaccggggg ccgagttccg
     6541 gtgcgcggac atccgtgacc tccctctggc ggagggagag ttcgacgcgg tctgtgtgta
     6601 cttctcgctg ctccagctgg agcgcggcga gcagagcgac ctgttggagc ggctcgtgcg
     6661 ctccctgcgg cccggcgggc tgctggccgc cgcgacggta ccggtggacg tcgcgggagt
     6721 cgacgcggtg ttcatggggc agccggtccg ggtgtccagc ttcggcgccg aggagttcac
     6781 cgccctgacc gcgcgggcgg gggtcgccgt ggagtggacg cacagcgcgc tgttcacccc
     6841 ggaccacccg gcgggcgaac ccgagccgca cttgttcgtg cacggccggc gcatctgacg
     6901 ccgcatacac acctttcgga actccccacc ccttggctat cacagagaac aagccgaatg
     6961 aatgactcgg gtggcgcatt tacgttcctt cacgagaagg taatgcgata gcaaagttct
     7021 ggtctatatg ctcaggtgta gttgtatccg tgcggagcgc ccggaggggg cctcatgacg
     7081 gctgccgtcc ggcaaaccac aggtgaggac cccttcatct attccgaaca cacatacgga
     7141 tataactagc gcattcgtca atatgacccg accacaccgc tccccggcag cgccggatgc
     7201 aggaggcagg ccaccatgca gtccctcgta gaacacgccc ggacattcac cgagcacgtc
     7261 gccgcgaacg caaaggattt cgaacgtttc gcggacggcc agacccccga agcgctcttt
     7321 gtcacgtgct cggactcgcg tgtcgtccct tcgctgatca ccggcgcccg cccggggcag
     7381 ctcttcgaac tccgcaccgc gggcaacatc gttccgccct acccgggccg ggaccggccc
     7441 accggcgagg ccgccaccat cgagtacgcg ctgtgcgtgc tccaggtgcg cgacatcatc
     7501 gtctgcgggc actcccactg cggcgcggtg ggcgcgatcc tccgcggcga cgacctctcc
     7561 gccatgcccg ccgtccgcca ctggctggag cgctccacgg acggccgcac accccccgac
     7621 gacgccggcg acctccccgg cgcggtccag gcccacgccc tcgcccagct cgacaccctg
     7681 cggggctacc ccgcggtgcg cgagcggctc gccgagggct ccctcggcct gcacgcctgg
     7741 tactacgaag tgcacaccgg ctccgtcagc gtgcaccgcc ccgagcgcgg caccgagttc
     7801 gcccgccttt gacggctctc cctcccccca cgtccccgcg ctcggccccg gccgggcgcg
     7861 accgtaccca caagggaagc catcgtgatt tccgcgaagg aactcaagaa cccccacgtc
     7921 gtacgacgtg acctgctggc gtcactcgtc gtcttcctgg tcgcgctgcc gctgtgcgtc
     7981 ggcgtcgccg tcgcctccgg agtcccggcc gaactgggcc tggtcaccgg catcgtcggc
     8041 ggactcgtcg tcggcctcct ccccggaagc aaactccagg tcagcggccc tgccgccgga
     8101 ctcaccgtcc tcgtcttcga agccgtcaag gagttcggcc tgagcacgct cggcccgatc
     8161 gtgctcgcgg ccggactgct ccaggtcgtg ctgggcctgg cgcgcttcgg tcgctggttc
     8221 cgcgccatct ccgtctccgt ggtgcagggg atgctcgccg gcatcggtct gatcatcgtg
     8281 ctgggccagg tgtacgccat ggccgacctc gaacagccgg gcagcggtct cgccaagctg
     8341 gccgggctcc ccggtctcgc ggcggacatc gtcacgaacc aggaggccct gaccgccttc
     8401 ggcctcggcg ccggaacggt cgcgatgctg ctgctgtggc cgaagctccc ggcccgggtc
     8461 cggatcgtcc cggcgcccct cgccgcggtc gccctggcca ccgcggtcgc ctccctggcc
     8521 gggctgcggc ccgcggtggc cgatgtcaac gggctgctga acgccatcga tctgcccggc
     8581 ggggcggagt tctcccggct cgccgatgtg gcggtcatcg gcaccgtcct ggccttcgcc
     8641 ctcatcgcct cggccgagag cctgttcagc gcggcggcca tcgaccggat gcacgacggc
     8701 ccccgtaccg actacgacaa ggagctggtg gcccagggcg tcggcaacac cctctgcggg
     8761 gcgctcggcg ccctcccgat gaccgcggtc atcgtccgca gcgccgccaa cgtccaggcc
     8821 ggggcgacca ccgcgctctc ccgggtcgcc cacggtctgt ggctgctgct cttcgccgcg
     8881 ctcctgcccg ccgccgtcgg gatcatcccg ctggccgcgc tcgccggagt cctcgtgcac
     8941 gccgggtgca agctggttcc cgccaaggag ttcggcccgc tctggcgcga acaccgtggg
     9001 gaggccgtcc tgttggcgat caccgcgatc gccatcgtgg tgaccaacct cttcgagggg
     9061 gtcgtgctcg gcctgctgct ggccgtggtc aagtcggcct gggagacctc gcacgtccag
     9121 ctcaccaccc atgagctcac cggcggccgg gtcgtggtga ccctcacggg gaacgccacc
     9181 ttcctccggc tgccccgcat cctggagcag ttggagaagc tcccgcagga ccagcccata
     9241 gagctggacc tcaccggact gcgccacctc gaccacgcct gccgggtcgc cctggagaac
     9301 tgggcccgcc ggcacaacaa cgcggagatc gaaccggtga cgatccgcca gtaagctccc
     9361 cgcccggggc ttctcgtccg gacctggacg agaagccccg gtagcgcttc gtcgccgcga
     9421 gcgatctcgc gagggcgggt ccgtggcgag cacaacagga gccacggggg acccgatcgt
     9481 ccgtcccgcc ggacgcagcc ctgcgacttc cagcgcgaag cgcgtgtccg cgtcggacgc
     9541 cgtgtcccca gccgtcggtg atcggcttgc cgttcaccag actccggccg accggccggc
     9601 ccgacgatcg cacatgcgag cgcctcgctc actcgatggt gggttctgcc tccccacccc
     9661 ccggtacgtg gggatcctgt gacagagggc gcgacctgcg ccggcgaaag cgtggaggcg
     9721 gggagcggca tgacgagcga atcgggccac ggcgaaactc tcgacgaacg tgcggtgctg
     9781 ctcgtggcgg gggcggccga cctggcggtg agcgcgatcg gttcggccct gggcgcggtc
     9841 cgagggctgc tgcgccgttc ggacaccgcc gagctggcgg cggaggccga gcatgagctg
     9901 aaggcccggg ggcggctggt gctggaccgg tacgcggccc cgccccctgc ccatctggag
     9961 atcctggccc gccaggccgt cgcacggcgg tccaccgaag atgtctgacc ggtgggacgc
    10021 ggcagcgttc aagacccggg tcgacgaggt cctgcatcag ttcgtcgccc gggaagtcga
    10081 tctgttcgcg aagatcgatc cctcactcgc tccggtggcc gcccagctgg aggccgccgt
    10141 ccaggacggc aaacggttgc gagccgcgtt ctgttactgg ggatggcggg cagtggggca
    10201 gccggacagc tccgcactgc tgcgggcggc cgcgtccctg gagctgatcc atgccgccgc
    10261 ggtcgtccat gacgacctca ttgacgacag tgctctgcgg cacggccgtc ccaccgctca
    10321 cgtcgccctg cgcggagccg tgcgacggcg tccccgttcc gcagcggccg ccaggtcgct
    10381 ggccatgctg gtcggggacc tgctgatggg gatggccggg cagttgttcg ccaccagcgg
    10441 cctgcccgcc gcctatgtgg gccgggcccg tccgctctgg tcggttctgg gccgcgagct
    10501 gatcgcaggc gagtgtttgg agatcctgcg taccggaagt gagccggaca ccgatgcgtc
    10561 cctacaggtg atccggtaca agaccgccaa gtacaccgtc gagcagcctc tgttgatcgg
    10621 tggcgcgctg gccggggccg gcgggcggct gcgcgaaggc tactccgcct acggcttgcc
    10681 tctgggcgag gcgttccagc tcagggacga cctgctcggg ctgttcggag accccgagca
    10741 caccggcaag gccaacgcgg acgacgtacg cgggcaacgg cccacagcgt tgctggcgga
    10801 gacctggcgc atcgccggtg aggacgaccg gacccgtctc cgggccctcc tgggccaacg
    10861 tggcctggac gaagccgggc tccaagccgt gcgtgaggtg atgtgccggt tgagatctcc
    10921 ctctctcgtc gaagacatga tcacggcacg ggtggaggaa gctctcggcg ccctcggaga
    10981 cctcgacctt ccggcgggcc cggccgatgc gctcggcgcg ctggcgaact cggccaccgt
    11041 ccgcctgttc tgaccctcgc cgctgccggc agcctcaacg acaaggaagc tacgtcatga
    11101 actacaccga ggcctcgatg aacgtcctgc ggcagggcgg cgacgaactg gccgacgcca
    11161 ccgtcgcggc gctcttcgag cgcggagagg tgggcaagtt caacaccctg atgcgccatg
    11221 tgtcgactac gggcacgccc cttccggacg ggctgcccga tgtcgcccgg gagtacctcc
    11281 ggaccacgag cgccccgccg gactgggtcg actgggagct gatggagaag gcccggctgt
    11341 tcttcatcga caacaacgtg cacatctcca ctgccctgtc gttcgcctcc atgccggcct
    11401 gctacgtggt tccgcacgtg gcgaggctgc tatcggccac ccacggactg aggtacccct
    11461 ccaaacgaat ggccgagacc ggccagttca ccgtctacct gatgcaaccc gatgccttcg
    11521 aggccggtgg ccgcttcatc cccgccgccc agaaggtccg tcttctgcac gcgtccatcc
    11581 ggcatcacct tcagcgcgag aaccgctggg acaccagcgc gctgggaacg ccgatctgtc
    11641 aggaggacat gatcggcggg cagatgttct tctccctgct cgttctcgac agcctgcacc
    11701 gcctcggcat ccacatgtcc acggaggggg cggaggccta ctactacgcc tggcgcgtgg
    11761 tcggggcgat gctgggcgtc gaccagcaag ccgtaccccc taccctggac gacgcccgag
    11821 ccttcctgga cctgtacatg gtccggcaca tgggcccctc cgaggagggc gctctgctca
    11881 cccggcagct catcgatctc tacgaggagg tcgtaccagg aaccctcttc gacccggtcg
    11941 tctccgcgct catccggcac ctcatcggcg acacctgcgc cgactggctc cgggtgcccc
    12001 gctcctcgtg ggacaccgcc gtcaaggccg tacctcacct cctcggtctc ctggagacga
    12061 tcgaggaccg ctcgccactg ggcgccaggg cactggacca cctcggccgt ctcaccaccc
    12121 ttctcgaact gtcctcgctc acccgcggac gcgtcatgca ctacgccatc cccgaacagc
    12181 tcaaggacgc atacggcgtc acccccgcct cacaccgcgc ccgccgctgg aatccccccg
    12241 ccgccacctc ctcaagctga tccacgggcc gacacgttgc cccctgccgc acagggccct
    12301 gaaccgcctt ctcctcggcg gccattccac agggcgcccc gccaattccc ttggtccaga
    12361 cctcttgacg attggtctag gccttcctag ggtcacggca acactgcgcg atcgccggcg
    12421 agagccctgt gctcacggtc ccgcagggtt gacgggccag ggattcccct gtccccctgg
    12481 agccactcat ggagcagcct tgagtacaca catacgatgg cgccgtaccg gatccccgcg
    12541 gagcgcctcc cccggcaagc ggtccagggc cgtcgcggga gccactgcgc tcctcgtgcc
    12601 actggccgcc atggtgggcc tcgcgacccc ggcgcaagca gccgcctcgg ccaccgccac
    12661 ctacaccaag gcatccgact ggggcagcgg attcgagggc aagtggacgg tgaagaacac
    12721 cggcaccact accctctccg cctggaccgt cgagtgggac ttcccggcga acaccaaggt
    12781 cacctcggcc tgggacgcca ccgtgaccaa ctccgcgaac cactggaccg ccaagaacct
    12841 cggctggaac ggcaccctgg cccccggcgc gtccgtctcc ttcggcttca acggatccgg
    12901 ctccggcgca ccctccggct gcaagctcaa cggcaacccg tgcgacggcg gctccaccaa
    12961 ccccggcgac aacgccccct ccgctccggg caagcccacc gcgagcgaca tcaccaactc
    13021 ctcggtgaag ctgtcctggg cggccgccac ggacgacaag ggcatcaaga actacgacgt
    13081 caagcgcgac ggtgccacgg tcgcaaccgt caccggcacc acgtacacca acaccggact
    13141 gaccgcgggc acggactaca gctactccgt ggtggcccgc gacaccgccg accagaccgg
    13201 accggcctcg gccgccacga cggtccgtac caccggtggc ggaggcggcg gtgagaaccc
    13261 cggcggcaac gggaagatca acctgggcta cttcaccaac tggggctcct acacggtgaa
    13321 gaacctcgtg acctcaggat ccgccgagaa gatcacgcac atcaactacg ccttcggcaa
    13381 cgtgcagaac ggcaagtgca ccatcggcga cgcgtacgag gactacgaga agtcctacac
    13441 cgccgcccag tcggtcgacg gcaaggccga cgcgtgggac cagccgctgc ggggccactt
    13501 caaccagctg cgcaagctga aggcgcagta cccgcacatc aagatcctct ggtcgttcgg
    13561 cggctggacc tggtccggcg gnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    13621 nnnnnnnncg gtctgacctg cgacaccagc ggcccggccg cgttcaagaa catgatgcag
    13681 gccatgcggg ccgagttcgg cccggacaac ctgctcaccg ccgccatcac cgcggacggc
    13741 tccaacgggg gcaagctcga cgccgccgac tacggaggcg ccgccccgta catcaactgg
    13801 tacgacgtga tgacgtacga ctacttcggt tcctgggcgg cgcagggtcc cacagccccg
    13861 cactccccgc tcacctcgta ccccggcatc ccggcacagg gcttcaactc ggcggacgcc
    13921 atcgccaagc tgaaggccaa gggcgtccct gcttccaagc tgctcctcgg catcggcttc
    13981 tacggccgcg gttggacggg ggtcactcag tcggctccgg gcggtaccgc cacgggcccg
    14041 gccgccggaa tcgagcccgg caaccagtac tacaaggtcc tcaagacgtc gtgcccggcc
    14101 accggcacgg tcggaggcac ggcgtacgcc cactgcggga acgactggtg gagctacgac
    14161 accccggcga ccgtcggcac caagatggcg tgggccaaga gccagggcct gggcggcgcg
    14221 ttcttctggg agttcaacgg cgacacggcc aacggcgaac tcgtgacggc catcaacagc
    14281 ggcctcaagt agccccggta cggtcccggg tccgcccgct ccccacagga gcgggcggac
    14341 ccgggaaccg gagcatccga actccggcgg cccggcggcc gctgatctcg ttcactgtca
    14401 ccctgcggct gcgcgcggga cccggattcc gggtcccgcg cgcagccgtg ccggatcagg
    14461 ccgcctgggc gaggagttcc gcgcggccga agaggagcgc gtaaccgggc ggcaggcagc
    14521 tgaccacctc ggcgacgagg tcgtcgccga ccagcgcggc gatctggctc aggaccaccc
    14581 cagcgtccca ccgggcggtc gccggggtgc ccccggtacg ctcggcgagc tcggcgacga
    14641 aggcggcccc ggcgagctgc ttcacggcag gcacttccgc ggtgaacacc cgggcggctt
    14701 cctcgggcag ggcggcggcg agtgcgacgc gttcgtcgcc ggtgatctgg cggccgagcg
    14761 cccccagcac ggcgcacagg ctctcctcgg cgcgttcacg cgtggggtag gcgccctcgt
    14821 accggatctt ctccaacagc aggccaaagg tcgtgtccat cggtgcgccg gcgttccggg
    14881 gttcgtgggt catcgtggcg gcagcccttc tcgtccgtac tgctcgtgtc gatgcgccgt
    14941 ccgcccccgc gactcgtcgt cgagcaggcg cgggggcgga cagcggtgga tcaaagttca
    15001 ggtgctcttc ggatgcccgc cgaagagcag gtcatacccg ggcggcagtt gaagcaggat
    15061 gcgtcgggtg agatcctcgc ccgccgcctc ggcggcgacg ctgaggacgg ctccgacgtc
    15121 ccaccgggcg gtctgttcgc cggctccctc gatccaggcc gcggtggcgc gcacgaaccg
    15181 ttccggggag agcggttcgg cggcctggag cgggttgagc aggatcagag ccatggtctc
    15241 cgggagccgg gcggccagtt cggcccgttc cccgcccacc aggtgggcac cgaggagggc
    15301 caggacgacg cgcgcggcgc gttcggcctc cccgtgcgtc tcgtactctc cgcgttcctg
    15361 gacccggtcc aggaacgctt cccatcgcag ggtcacctca gccgcctccc agggtggtgc
    15421 gggcgggggc cggaaccggg ggggggggga agaaggggat ctgcgttccg gtccccgccg
    15481 ctgtcgcggg ccggcccggg tcagcccttg atctgcttgc gccgggactc cccgccgatg
    15541 gcgatcttgc ggggcttggc gcgctcggcg atcgggatgc gcagggtcag cacacccgct
    15601 tcgtagtcgg cgtcgatgcg ctcggtgtcg agcgtgtccg cgaggacgat ctgccgggag
    15661 aagacgccca gcggacgctc ggacagctcc atctgcacgt tgtcggcgtt caccgccggc
    15721 cgacgttcgg ccttgacggt cagcatgttc cgctcgacgt cgatgtcgat cgcatccggc
    15781 gagacgccgg gaagatcgaa ggccaccacg tactcgtcgc cctcccgata cgcgtccatc
    15841 ggcatcgccg aggggcgcga ccaggtgccg gggcgcagga gttgctcggt gatccggtcg
    15901 agttcacgga aggggtcggt acgcatcagc atgacggaaa cacctccggt cgatcaggcg
    15961 gtcagcccgc gcttttcacc tgccaccgtt gtagcatgtc atccattcga tgacaactga
    16021 ccgtgtcacc gaaaggatga cggcatcgtc gagcgcagcg aggagccccc tgtgacccca
    16081 ccgacccaac ccgaaccgcc ccggcgttcc accccggacg ccgtctcctt ccttgccgcg
    16141 tgggcggccc tccagaccat cgacgaggcg gtccgcgacg cacacggcca cgccggggac
    16201 gccacctccg gtccgccacc ggccacggag cgggccgagg ccctggcctc gctccagctg
    16261 ttgcgcgagg tgcgggagca gctcgcgggc tgggagaccg gcctgatcga gacggcccgc
    16321 gcggcggggg cgagttgggc cgacctcgcc gacccgctgg gcgtcgcgag ccggcaggcg
    16381 gccgagcggc gctatctgcg cctgcgtccc ggctccgagg gcagcaccgg ggagcagcgg
    16441 gtccgggcga cccgggaccg ccgggcggga gaccggtcga tcaccgcgtg ggcccggcag
    16501 cacgcggcgg atctgcggtc gctcgccggg cggatcgcgg cgctgaccga tctccccgcc
    16561 gcggcggacg ccccgctgga ccggctccgg caggccctcg gcaccgacga cgccgccgcc
    16621 ctggtcaccc cactcaccgc actgcacccc catctcgctc cggggcacgg tgagttggcg
    16681 gatcgcgtgg acgcactgac gcagcacacc ggtcggctgc gtgaggacac ggccgcccgc
    16741 cggcgcggcg actgaccgca cgagggcggg tccgggcaca tccgcccgga cccgccgtac
    16801 gaccacgact gccggttcct ggctactgct gccgaccacg gcctccggct acggtttgcg
    16861 ggcgacgagc ccccactggt cgaccggcac cgcgtcctcc tcctcgggcc gccagcggtc
    16921 gatcgggacg aaacccggct cgaccagctc cagcccctcg gcgcacccag tgatctccgc
    16981 cggctcccgc acgaggtagg gcgggttgtc gcccgacgcg tacgcctcct gcgccgccag
    17041 cgtctgcggg gtcttcaccg tgtcacagag caccagatgg cttcccgacg gcatccgggc
    17101 cagataccgc tggacgacct cgatgccctc ggccggcacg aggtgcccga gggtcgagag
    17161 caggagcacg gcgacgggct cggacaggtc gagagtcttc gccgcctcgt ccaccaccac
    17221 gtccgtcgcg gagaggtcgg cgtccacgta ggccgtacgg ccctcgggcg cgccggtcag
    17281 gagcgcctcc gcgtgggcga ggacgatcgg atcgttgtcg acgtagacga cgcgggactc
    17341 cggcgcgatg ctctgcgcca cctcatgggt gctgttcgcc accggcaacc cggtcccgac
    17401 gtccaggaac tgacgcacgc ccaccgagac gagatggcgg atcgcgcgga tctggaaggc
    17461 gcgggaggcc cgggcgatgt cggccatctg cgggtaggcc gcgctcaccg cctcggccag
    17521 ctcccggtcc accgggtagt ggtcctttcc gcccagccac gcgttccaga cgcgcgccga
    17581 gtgggggacg tcggaccgga tgctgcggcg gaactcgtcg tcgtcggcgc tcatggctct
    17641 cctctgcccg cttcccgtac ctgacggtcg accggacgca cgccgaccgg cccccggtgg
    17701 cgaccgtacc ccgcgccccg gcaccacgca ccggtgacgg agcggtcagg cccgcgggcg
    17761 ctcaaaaaag ccggcccacg aggccgaaga tccagctgat cagcaccgcg agcaggatga
    17821 agatcccgac ggtgatgaca ccgcaccacg accagccgcc tccggtgtcc agcccccggt
    17881 cgtcccgtcc gcccagctcc ccgtcgaaca gatccatgct ccacgcctcc cccgtacgcg
    17941 gaacccccgt gttccgcggg aatgcactct cccacaccct cacgtggcca cgatacggat
    18001 caggatcgtg accatcggcg ttcagatgag ggcgtgcgcc ccgggcgacc gcccgggagg
    18061 cccaggccct cggccggtgc acggtcagcg tcggcgaccc ggtgcacaac ggcaaccacg
    18121 tccgggccga ggctccgtgg aactgttcca cgctgcctcc gtacggtggc gcgaagacca
    18181 aggtgaacct ctaccgggac ggcgtcctgg tgaagagcgc cgagttccgg ccgaacggcc
    18241 tgctgaacgc ccggtacggc cgggcccggc cgtctccgtc ggtgcggtcg gatacgcgta
    18301 cgggatgacg tgcgccgccg ccgtatgcgc ctcaggtcgc acacgggcgc gacgtgagcc
    18361 cgatgtgccg gacccccgcc ggatccgacg atgggcgcat gaccgaaccg accgcggggc
    18421 tgccgttgtc cgccccggaa gccctcacgg tgctcggggc gctcgtcctc gtcctggccc
    18481 gctggctccc cgaccggctg cgcggcccgg ccgcgctcgc cgccggagcg ttgctggccg
    18541 ggtcggtgac cgtcctcgtc gcgacgggga cgcgctggca actggtcccg gtcctcgtcg
    18601 tggcggccgt cgccggcggg ttcgcgctcg ccccactgct cgcccgccgc tccggccgca
    18661 caccgtggcg ggcccggtgg tggctcgcgg tgcccgggtc ggtggtgtgc gccgccctcg
    18721 tcgcgacggg gccggtgtcg gcgtgggcgt ttcccgtacc ggacttcccc gcgccgtcgg
    18781 ggcgcttccc ggtgggcacc gagacggtgg agtggtcggt gcccgcgacg cgatccgagc
    18841 gggagaagcg accgcgtgtc gccgggccgc gcccgctcgt ggtgcagctc tggtacccgg
    18901 cggggcgcag cgctccggag gcccggcgcg ccccgtacct cgggcgtaca gaggcggagg
    18961 cgcgtacggt ctcggcggcg ctggccgact acgcgggcgt tcccgggttc cttctcgacg
    19021 gtctgccacg cgcccggagc cacgcggtgc ccggcgcacc ggtcgcgaac ggcggcggac
    19081 gtttccccgt ggtgctgttc tcacccggac tgggcggtgc gcgcacccag aacaccgcct
    19141 gggccgagga actcgcctcc cacggctacg tcgtggcggc ggtcgaccac ccgtacgact
    19201 ccgccgccgt ggtcctctcc gacgggcgga ccctccgtac ccgggtcacc gccaccggcg
    19261 accgggcgaa ggaccgggcc ctggcggaga agtggacccg gacgcgggcg gcggatctgc
    19321 gcgcgatgct cacccggctg gagcggctgg aacgcggtgg ggccgaggga cggttggccg
    19381 ggcgcctcga cgtcggccgg gtcgcggccg ccgggcattc gatcggcggc gcggccgctt
    19441 tgcgggcggc ccgccaggac ccccggttcg acgcggtcgt cgatctggac ggcttcccgc
    19501 acgggcccgt cggcggtcgc ttcgagcagc cggtgctggc gctgacccag gagatcgggc
    19561 ggggcacgga cccggactac ctgccccggc tcacccgggt gctcgaacgg agcgacgcga
    19621 cgagctaccg gctgaccgtc cccggggccg cacacctcac cttcaccgac gccccgctct
    19681 atctgccgcc ggtcccgggg atcgtgggct ccctgggccg tacggagggg catcggatca
    19741 ccgccggggc gaccctgtcc ttcctcgacg ccaccttgcg ccgcgccccc gtcgacgtgc
    19801 ccgccgcgct ctcggcccac ggggaggtga cggttcaccg gccggagggc gctcgctgag
    19861 caccccggac ccgggcaggt cgaacagtgc gccggacgcg atcttgatga ccggccggtc
    19921 ggcgagttcg cggtgcacgg gcgatccctc cggccggggc ctcgatgggc tcgcccccac
    19981 ggtcacaccg gtgcaggacc gcgttcagct cagcagcagg gcgctgtccc aggaggtgac
    20041 cggcgcacgg ccgatggcgt acgtgtgcag agccagggcg atgcccgccg ccccctccag
    20101 gaagccgggg cggtcgagcg gtcggtgcgc gagggcgtgg gcgtagcgga agccgaacgg
    20161 ggccccgggg tcgaatccgt ccagcacccg ggccgccaac cggtcggcgg tggcgtggag
    20221 ttccgggtcg tcggtgtcct cggcggtgcg cagcacgatc tggaggaggc cggcccagcc
    20281 gtggcacagc gcggagtcac ggatcgactc gtcgctcgcc accgccagcg caccgcgcag
    20341 tgcggcctcc gcgtcggcgc gccactccgg ccggtccagc gcgcttccgg cgaggtggac
    20401 ggcgcgggcc gcaccggccg ctccgtagca ccaggagtcc cgaccgcgct ccggcggctc
    20461 ccccttctcg atgcgctccc gtgacatcag gtgcggccag cgcgggcccg cctcgtcaaa
    20521 ggtgcgcagg ctggtcagca gcgccatggt ccgttcgatg gcctcgtcct ggcggtccac
    20581 ccggaccccc gcccgccagg cgagggcgag cagggccagt gggccgggga caccgtgggc
    20641 gaggccgagg ttgacgtgct cggggagccc gtggtccagc ccgtcggtga tccaccacgc
    20701 gggcagccgg gaaccgtgcc gggtgatgtc gtcggcggnn nnnnnnnnnn nnnnnnnnnn
    20761 nnnnnnnnnn nnnnnnnnnn nnnnnntccc ggcggtgccg gcgaggacgt cgtagcggct
    20821 ccacgctccg gcgggctccc cggcgcgggt tcgctccagg tcggcgcggg cgcgggtgcg
    20881 gacccggtcg aggatgtgcc ggtccagtcc ggcgagcatc gcggtgtagc cgccggagcc
    20941 ggcggccgtc gtgtgcccgg cgtacgcgag cgccaccatg ccgccgaaca gcgactgggg
    21001 cgccggcctg accccggccg cgaggcccgc ggacaggtgc gcgtgggccc ggt
//
