LOCUS       NZ_BMSZ01000010        22214 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces badius strain JCM 4350 sequence10, whole genome shotgun
            sequence.
ACCESSION   NZ_BMSZ01000010
VERSION     NZ_BMSZ01000010.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces badius
  ORGANISM  Streptomyces badius
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 292234)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: BGI assembly pipeline
            Genome Coverage                   :: 154X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014649415.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 03:57:07
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,894
            CDSs (total)                      :: 6,825
            Genes (coding)                    :: 6,582
            CDSs (with protein)               :: 6,582
            Genes (RNA)                       :: 69
            rRNAs                             :: 2 (23S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 244
            CDSs (without protein)            :: 243
            Pseudo Genes (ambiguous residues) :: 0 of 244
            Pseudo Genes (frameshifted)       :: 70 of 244
            Pseudo Genes (incomplete)         :: 206 of 244
            Pseudo Genes (internal stop)      :: 7 of 244
            Pseudo Genes (multiple problems)  :: 38 of 244
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:11:55
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 13496
            Orig. end                         :: 35710
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMSZ01000010.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22214
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22214
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22214
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12214](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12214
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(363..1154)
                     /locus_tag="IE135_RS17885"
                     /old_locus_tag="GCM10010253_36110"
     CDS             complement(363..1154)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019766343.1"
                     /locus_tag="IE135_RS17885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_36110"
                     /product="DUF4389 domain-containing protein"
                     /protein_id="WP_069735062.1"
                     /transl_table=11
                     /translation="MAEGQWSPGRKEADADEFRPVLDIVEPARQRRLTVLLRLLLLIPH
                     FIVLFFLHIAAFFTVIVGWFAALVLGRLPDPVFRFLTGVLGYDMRVSASDMLLIDRYPP
                     FALTPPADYPVQIEVRPTPLNRLAVLFRVFLMIPAAIVQSLAVYGWWALAFVWWLITLC
                     LGRMPRPLFEATAATLRYRMRFSAYVMMLTPAYPKGLFGDDALAVPPEQARSATRPLIL
                     SSAAKWLVVLFLVLGLAGHITSSLTASTTDDTTDTQLTGAP"
     gene            complement(1267..1941)
                     /locus_tag="IE135_RS17890"
                     /old_locus_tag="GCM10010253_36120"
     CDS             complement(1267..1941)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014158023.1"
                     /locus_tag="IE135_RS17890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_36120"
                     /product="VanZ family protein"
                     /protein_id="WP_069735063.1"
                     /transl_table=11
                     /translation="MTAEANPPARQRTWVRVLVRGAVLSVVLLGLVAFSVLLAKVTLTP
                     SPASEDIVTANLRPGRSLRQYAEDYTFLAACKQAGGNLLLGVPFGLLLPFFVPRRLRMI
                     RTTLLTAVAMAVVELIQGALVQGRAFDIDDVILNTAGALLGYFVLGRRISHRYYAYSDV
                     PRSSEPRDEPKPGPAPRPKRTGTKGTGAKRTGTGSAAEKTTDVKSAGAKAPRPLLDRLR
                     RR"
     gene            2040..2540
                     /locus_tag="IE135_RS17895"
                     /old_locus_tag="GCM10010253_36130"
     CDS             2040..2540
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971171.1"
                     /locus_tag="IE135_RS17895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_36130"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_199888534.1"
                     /transl_table=11
                     /translation="MSTEKKKDLLDEADRLREGGRPEEARERLLALTAEYPDDAEVACR
                     TAWIHDVLGLESEAVPYYERALADPELSAEDRRGTLLGLGSTYRVLGRYGQGVETLRRG
                     VEEFPDDGAMRTFLAMALFNTGEHDEAMRLLLELTAATSQDPYVQQYRRAIEHYAKDLH
                     ETV"
     gene            2644..3267
                     /locus_tag="IE135_RS17900"
                     /old_locus_tag="GCM10010253_36140"
     CDS             2644..3267
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010060704.1"
                     /locus_tag="IE135_RS17900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_36140"
                     /product="DUF1275 domain-containing protein"
                     /protein_id="WP_199888535.1"
                     /transl_table=11
                     /translation="MSSAPPALPPSPPSASSSGGSRTGDAPWGGEAALLLLSAASGAAD
                     AFVAAAGALMAGRWGYRVPALLGVEVVLLGAAAALWGLELVSSYGDRLGLLSLVAVAMG
                     VQGRVRVTPTNYFTGTLTSLAGRVALRKLRGGDGWVLGRLAAVVAGAAVAALAERWWSP
                     GAALGAVVMAAGALALETVWGRGGRLRPDRRKPRPDRGNPAGAA"
     gene            complement(3492..3752)
                     /locus_tag="IE135_RS17905"
                     /old_locus_tag="GCM10010253_36150"
     CDS             complement(3492..3752)
                     /GO_component="GO:0005840 - ribosome [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606682.1"
                     /locus_tag="IE135_RS17905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_36150"
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="WP_199888536.1"
                     /transl_table=11
                     /translation="MKPRIHPVSRPVVFRDRAADVAFLTRSTADSGEHVVWEDGSTYPV
                     IDVETSSASHPFYTGGTRVLDTAGRVEQFRRRYGTGEASGS"
     gene            complement(3817..3981)
                     /gene="rpmG"
                     /locus_tag="IE135_RS17910"
                     /old_locus_tag="GCM10010253_36160"
     CDS             complement(3817..3981)
                     /GO_component="GO:0005840 - ribosome [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpmG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010470368.1"
                     /locus_tag="IE135_RS17910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_36160"
                     /product="50S ribosomal protein L33"
                     /protein_id="WP_069735066.1"
                     /transl_table=11
                     /translation="MARSESRPVVTLRSTAGTGRSYVTRKNRRNDPDRLELRKFDSAVG
                     RHVLFREVR"
     misc_feature    4029..4044
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.8"
                     /tool="antismash"
     misc_feature    4031..4045
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.65"
                     /tool="antismash"
     misc_feature    complement(4032..4047)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.07"
                     /tool="antismash"
     misc_feature    4170..4185
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.28"
                     /tool="antismash"
     gene            4338..5768
                     /locus_tag="IE135_RS17915"
                     /old_locus_tag="GCM10010253_36170"
     CDS             4338..5768
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956434.1"
                     /locus_tag="IE135_RS17915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_36170"
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /protein_id="WP_199888537.1"
                     /transl_table=11
                     /translation="MPSPLFADRPAPQLPAHDAVDDLIHRTRRLRGDVDAVRRDAVMSD
                     EDDPQLRWQRALCELAVHHLDTLGEHLGQLRAGLPGPRAGGSAPGGEEAPKDPKAGSLL
                     SRVGSAEWNLLTDESSWSEELYEIFGRPLDSAPLSLDDLPSVLLPEDQPVLTAMVTGCL
                     VDGRPMDGEFRIVRPDGDTRTLHMTGEPVLDAEGCTASMWAVLRDVSELRRSEQAVTRS
                     RASVQREEHIERAEHRMAVELQETVLPPWRGSLRLPPQGPGALDIAAHYLPSASSGLIG
                     GDWYDAMELPDGRTLLTVGDLTGHGIPATSAMAMLLGALRGMAVAGIEPGALMGHLNQV
                     LETTMQPALGSALCCRFDPGTSVLSWAQAGHPAPLLFRGGSGRLLPPPDGILLGAAPQA
                     VFEQDEVRLFPGDVLVLHTDGLTRRGDRGAGPEALLALAPRFAEARTAQECVRGVVEEF
                     GGTERLDDACVLVARIGA"
     gene            complement(5854..7341)
                     /locus_tag="IE135_RS17920"
                     /old_locus_tag="GCM10010253_36180"
     CDS             complement(5854..7341)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458453.1"
                     /locus_tag="IE135_RS17920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_36180"
                     /product="hypothetical protein"
                     /protein_id="WP_199888538.1"
                     /transl_table=11
                     /translation="MTGEPNTRLSDLFGLAGWSKGELARMVNRQAAAMGHPQLATDTSR
                     VRRWIDMGESPRDPVPEVLAALFTERLGRVVTIEDLGFGRRGRVGKRRDSGTENNPDQL
                     PWAPERTAAVLTEFTGMDLMLNRRGLVGAGAALAAGSTIAGPMYDWLHSDPAPAADAPR
                     TNDPLHADPAGFDRYEAAPVGSEEIEALEHSVEVFRAWDASRGGGLQRKAVVGQLNEVG
                     GMLAYRHPDHLQRRLWGVAANLAVLAGWMSHDVGLEPTAQKYFVIAAHAAREGGDRPRA
                     GEALSRAARQMVHLGRPDDALDLMKLAKSGSGDETLPRTQAMLRTIEAWAQASMGRGQA
                     MRRTLGEAEELFVSDKSDVPPPSWMQMFDEADMHGMQALAFRTLAEHDPGAAIIAQRHA
                     KQALELRVNGRQRSKIFDYISLASACFIANDPEQADRYARLALVSMGETSSHRTWDRLR
                     EMYRLTGQFAGYAGIQDLREEIELSLPSQKKARGAQI"
     gene            7573..8709
                     /locus_tag="IE135_RS17925"
                     /old_locus_tag="GCM10010253_36200"
     CDS             7573..8709
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010060711.1"
                     /locus_tag="IE135_RS17925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_36200"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_069735069.1"
                     /sec_met_domain="APH (E-value: 1.3e-18, bitscore: 61.9,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYTASSSVSAPPRPLRPMGAGGGPYLAPHAGAPVQGPGRARRAAG
                     PGAGPLSGRIDLSGPQGAQVRMAIASVQRICPEFNPVQVLRRSGRSVLIVGTTGRATAV
                     AKCLLDHSPAWTERFRHEIAAYRAFVRHRPPVRVPRLIAADPENCTLVIERMPGRVAAL
                     TRHPAEAPPRADIRAALGAIARVNAWRPPPGLFEAPLDYASRIARYHELGLFTDRDLGD
                     LQKLLHGLAHAGGRQGMGQFCHGDALLSNILLSPTGPVLVDWEHAGWYLPGYDLATLWA
                     VLGDAPVARRQISQLAQARGPAARDAFLVNLMLVLTREIRNYETAVQRTMREAPVAGAG
                     ADRPGALSSGEEQRLLLRRLHDDCAMARRAVRAAVGTR"
     misc_feature    7894..7896
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            9199..9864
                     /locus_tag="IE135_RS17930"
                     /old_locus_tag="GCM10010253_36210"
     CDS             9199..9864
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971163.1"
                     /locus_tag="IE135_RS17930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_36210"
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="WP_069735070.1"
                     /transl_table=11
                     /translation="MPRISTLRITRSHKIATAVLVAAGSVTAITATGGPSEAQTTATRS
                     SVSVEPVAAAGIPTAKDAAEKAAKENAAKEAAAKKAAAKATAKKAAEKERSEKQAANRS
                     TERKAVTPKKYANNLDGWIRESLDIMKKKNIPGSYEGLHRNIMRESSGNPNAVNDWDIN
                     ARNGIPSKGLLQVIQPTFDAYHVKGTPKNLTDPVANITAAANYAADRYGSIDNVDSAY"
     gene            10001..12214
                     /locus_tag="IE135_RS17935"
                     /old_locus_tag="GCM10010253_36220"
     CDS             10001..12214
                     /EC_number="4.2.3.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971162.1"
                     /locus_tag="IE135_RS17935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_36220"
                     /product="terpene synthase family protein"
                     /protein_id="WP_199888539.1"
                     /sec_met_domain="T1TS (E-value: 5.3e-86, bitscore: 283.7,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQPFSLPDFYVPYPARLNPHVEAARSHTREWARSMGMLEGSGIW
                     EEKDLEAHDYALLCAYTHPDCSAEALSLVTDWYVWVFFFDDHFLELFKRTPDRAGGKRY
                     LDRLPAFMPMERGAATPEPENPVEAGLADLWARTVPAMTDDWRARFAESTENLLNESLW
                     ELANIHEGRIANPVEYIEMRRKVGGAPWSAGLVEYAANAEVPASVAGSRPLRVLRDAFS
                     DAVHLRNDLFSYQREVEDEGENSNGVLVLEKFLGCSTQEAAEAVNDLLTSRLQQFENTA
                     LTELGPLCAEKALDPAQTAAVLAYAKGLQDWQSGGHEWHMRSSRYMNGGGAGEAVPGLG
                     MSAASIRFTLRSEAARARSHSHVPYQHVGPSLLPDFELPFTTTLSPHLEGARGRLVEWA
                     RRMGILEAQPGVPGSHIWDEERIRAIDLPLCAAGIHPDASPDELDLSSGWLAWGTYGDD
                     WFPVVHGRARDLAGARLANDRLSLFMPLDDEGTPEPVNALERSLGDLWRRTAGPMDRDA
                     RRTFRTAIETMTESWLWELANQAQNRIPDPVDYMEMRRATFGSDLTMSLCRLGHGRKVP
                     EEVYRSGPMRSLENAAADYACLLNDLFSYQKEIEYEGEVHNGALVVQNFFGVDYPTGVA
                     IVHDLMNSRLRQFRHVAEVELPVLYDDFGLDAEAREILAGYVRELEHWLAGILIWHRGC
                     RRYREEDLRSGHAAPWHLGGPTGLGTSAAQVTRMMTPLAGSRG"
     gene            complement(12491..12991)
                     /locus_tag="IE135_RS17940"
                     /old_locus_tag="GCM10010253_36230"
     CDS             complement(12491..12991)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018550733.1"
                     /locus_tag="IE135_RS17940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_36230"
                     /product="hypothetical protein"
                     /protein_id="WP_003971159.1"
                     /transl_table=11
                     /translation="MSFLRRRSAATPAGPDFDVLAMDPGDWPGNLGAGLLPAPDGSCQG
                     VFLRYDLYGGRGPAMIIGNLPEGSPARETEEGQVPFEVAQLLLALENDEPIEVVSSEDV
                     PVMQGDNLLIVRRVKLSESRIACVQFDRSDGVLVTIASWDRPITDDLYTLLKPLPAELF
                     QQG"
     misc_feature    12995..13005
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.79"
                     /tool="antismash"
     gene            complement(13069..>13734)
                     /locus_tag="IE135_RS17945"
                     /old_locus_tag="GCM10010253_36240"
                     /pseudo=""
     CDS             complement(13069..>13734)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971158.1"
                     /locus_tag="IE135_RS17945"
                     /note="Catalyzes the synthesis of acetoacetyl coenzyme A
                     from two molecules of acetyl coenzyme A. It can also act as
                     a thiolase, catalyzing the reverse reaction and generating
                     two-carbon units from the four-carbon product of fatty acid
                     oxidation; incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_36240"
                     /product="thiolase domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="HKDRRNALKNPYAHIHDHDLTLEKVQSSPMLWDPVRYSETCPSSD
                     GACAMILTGRDGAARSPHPPAWVHGGAMRSEPTLFAGKDFVSPRAGKDCAADVYRQARI
                     TDPRREIDAVEMYVPFSWYEPMWLENLGFAEGEGWKLTEAGVTELDGDLPVNPSGGVLS
                     TNPIGPSGMIRFAEAALRVRGRAGEHQIDAATRALGHAYGGGSQFFAMWLVGTEPPPG"
     gene            <13725..14326
                     /locus_tag="IE135_RS17950"
                     /old_locus_tag="GCM10010253_36250"
                     /pseudo=""
     CDS             <13725..14326
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012382252.1"
                     /locus_tag="IE135_RS17950"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="GCM10010253_36250"
                     /product="acyl-CoA synthetase"
                     /pseudo=""
                     /transl_table=11
                     /translation="GPCVVVHRKFVPEEVLRTIEKEKVTSVSLVGDAMLRPVSRAASPS
                     ADMCRSATTTIRPRPPTPSSTGAMSAGCCWATWRPWTRTASSRCSGGARSASTPMGRRC
                     IRRRSSRRSRRMRMCTTRSSRASPTSAGESGSPPWSNCARVRLC"
     gene            14532..18194
                     /locus_tag="IE135_RS17955"
                     /old_locus_tag="GCM10010253_36260"
     CDS             14532..18194
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012298.5"
                     /locus_tag="IE135_RS17955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_36260"
                     /product="WD40 repeat domain-containing serine/threonine
                     protein kinase"
                     /protein_id="WP_199888540.1"
                     /sec_met_domain="Pkinase (E-value: 7e-40, bitscore: 131.1,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSPLTQDDPERIGEYWLAARLGAGGQGVVYEAYDASGARFALKT
                     LHRAADPFLRERFTREAEAARRVAPFCTARIVRAGVDGEVPYLVSEYVAGPTLAASVRE
                     NGTSSPDAVLRLATGVATALAAIHQAGVVHRDLKPGNVLLGPDGPRIIDFGIARAPDMS
                     LTATGAIMGTFGYMAPEVLAGQRATEASDVFAWAAVVLYAATGTEPFRGENIAEVAHRT
                     TTVEPDLGALPPEVRPLLAAALAKDPELRPTAADLLLGLVGAPVKAADPRAALMEAGAR
                     KAAAPGADGPMATGTDGAGSGDGAGGVGGTVVEAPLGERAEAAYAALSPAAQLAAHGLL
                     LRLTVPGAAADGSQDSVRTAHPDELLADRPEGEQQEVTAAAQRLLAAGVLASEADGALR
                     PASAALLPAWRRLHAWVDADRPGLAVLQRIGTAARLWQRHGERPEDLLRGTELTRCLDW
                     LPTAPYSLRPNPLEQRFLTASRATVARTTRRRRQLLSGLAGATALALLAGGLAWTQSRE
                     ADRRRAEATARAVARAAENLPATEPETAMLLGLASWRIAEVPEARAALAAAAVQPVRSV
                     IDLSDVNDGEEQSSHLSRDGRRLIASSSLGVRIHDLAGGQAALKKPVATLSPEEFALDD
                     TRRPAFSPDGRLMLLVAEDGTFRVMNTEDGTPAAPPVRAPSGYFEGEAISNSGHMLLSD
                     GRSTALADRDGNGLAVVPRGSTLTPDGSYSAGCEGGELRVAGLLPGEAPVIREELPDKA
                     GPCGFEFSPDGRHMSVRIGSTANLYDLVTHKRTGSMRHRGDGLRFGSQGRFLVGWGNDG
                     TTIDVWARGSEEPLFTVTAPTGQGDKGMYAHQLALDEEAERLRYFSTTTGRLYEIDLAG
                     ALSGRADRRVTAAVSAGGRFGLVRSAPSSVDPPTLQAVDLRTGEPVGDLVAQREAGDPL
                     EGEELFASIDDEGRVMAYSYRERVSRYETDDEVVVRDVREGKNLHRVPVAANHRPLHLA
                     VSPDGRHLSLVSQEFGVNSADSHIHEVWDIEKRTKIRQFNDRTAEAVFSHDGERLVTAA
                     GTEVTLADGAVRKTGLARDPGGRPVFSPDGRYLAVLKESGWLELWDGAVREREAVLASE
                     LVPGATRFGQPLGDLAFSADGSLLAVAVRGEAVQLWETSTRTPLGNPLPITGRRVDALA
                     FEGTRLRTVTGSAVHRLDLSPDRLAEQVCRRAGRDITPQEWRTYVPDAPYRSLC"
     gene            complement(18221..19216)
                     /locus_tag="IE135_RS17960"
                     /old_locus_tag="GCM10010253_36270"
     CDS             complement(18221..19216)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1015: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971138.1"
                     /locus_tag="IE135_RS17960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_36270"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_199888541.1"
                     /transl_table=11
                     /translation="MLSAGRFRTDTMPRGDRFAYWHTYMADVVAPMEISSPYAHDFRAE
                     YRLLRIEDAALWPTRAPASRYRRTPRLIRKSDPELLHMTLVQPGSGSVQVEQGTVRSAV
                     APDDIYFIDTSKPYEVATVDAPIRGIGLDLPRSQLPLPPSTSLDGVVGRRLSGRHGFGA
                     LISQILLHLVDQTEVYGPADGPRLHRVLLDLMAGVLADGLDQESALSPEARSHNLVLAI
                     RSFIGGNLHDPRLTPAAVAAAHHISTRHLHRLFQQEGTTVAALIRNRRLERARRDLAEP
                     GLAGTPVHVIAARCGFGSPAHFSRVFRAAHGMSPVDYRYAKLRESDESAN"
     gene            complement(19210..20760)
                     /locus_tag="IE135_RS17965"
                     /old_locus_tag="GCM10010253_36280"
     CDS             complement(19210..20760)
                     /NRPS_PKS="Domain: Abhydrolase_1 (21-267). E-value:
                     2.1e-27. Score: 88.3. Matches aSDomain:
                     nrpspksdomains_IE135_RS17965_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956456.1"
                     /locus_tag="IE135_RS17965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_36280"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_199888542.1"
                     /sec_met_domain="PF00561 (E-value: 4.1e-25, bitscore: 83.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.4e-19, bitscore:
                     65.7, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTFSAYDTTPLAWHPVGEGEPLICLPGGPMRASAYLGDLGGLAA
                     RRRLILLDLRGTGASGVPEDPSTYRCDRLVDDVEALREHLGLERVDLLAHSAGADLALL
                     YAARHPERLRTLTLVTPSTRAVGIEVTDDDLREAAELRRGEPWYPEARAAQEALLAGGP
                     FAELWPAVRPLTYGRWDEAARAHAEASAGQTNAEARQRYPGEGAFDPAATAAALREVTV
                     PVLVLAGEYDGHPGPDRAAELAALFPGAEFVVQRGAGHFPWLDDPGAFARTVEAFLDPE
                     ILSVQAGGVRLSYRVWGAPDAPPVVLLHGRTGSGETWTRIARDLAADHRVYAPDFRGHG
                     LSDWPGRYSFEMFRDDLHAFLEARNLAGATVVGHSMGGVAAYLLAQREPGLIGRLIIED
                     APPLLPLDPPRPPAVRPDGDLDFDWPVVPDTDAQLNDPDPAVRERFPEITVPTLVIGGG
                     PDSHIDQEQLARMVRAIPDAELVTVDAGHLIHTDRPREFLAAIRAFGLHGREGGGDAC"
     CDS_motif       complement(19600..19650)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE135_RS17965_0002"
                     /evalue="3.90E-05"
                     /label="NRPS-te1"
                     /locus_tag="IE135_RS17965"
                     /protein_end="387"
                     /protein_start="370"
                     /score="16.2"
                     /tool="antismash"
                     /translation="VVGHSMGGVAAYLLAQR"
     aSDomain        complement(19960..20697)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE135_RS17965_Abhydrolase_1.1"
                     /evalue="2.10E-27"
                     /label="IE135_RS17965_Abhydrolase_1.1"
                     /locus_tag="IE135_RS17965"
                     /protein_end="267"
                     /protein_start="21"
                     /score="88.3"
                     /tool="antismash"
                     /translation="PLICLPGGPMRASAYLGDLGGLAARRRLILLDLRGTGASGVPEDP
                     STYRCDRLVDDVEALREHLGLERVDLLAHSAGADLALLYAARHPERLRTLTLVTPSTRA
                     VGIEVTDDDLREAAELRRGEPWYPEARAAQEALLAGGPFAELWPAVRPLTYGRWDEAAR
                     AHAEASAGQTNAEARQRYPGEGAFDPAATAAALREVTVPVLVLAGEYDGHPGPDRAAEL
                     AALFPGAEFVVQRGAGHFPWLDDP"
     CDS_motif       complement(20440..20478)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE135_RS17965_0001"
                     /evalue="5.60E+00"
                     /label="NRPS-te1"
                     /locus_tag="IE135_RS17965"
                     /protein_end="107"
                     /protein_start="94"
                     /score="-0.2"
                     /tool="antismash"
                     /translation="HSAGADLALLYAA"
     misc_feature    20779..20794
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.45"
                     /tool="antismash"
     misc_feature    complement(20952..20966)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.75"
                     /tool="antismash"
     misc_feature    21441..21460
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: medium, score: 24.1"
                     /tool="antismash"
     misc_feature    21460..21473
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.89"
                     /tool="antismash"
ORIGIN
        1 ccccggttca ccgcccgcga ggtgcccggg ggcgatgtgg ccgcgttcgt ggccgcccgg
       61 ttccagggct ccggcggccc cggcgtctgg ccctgccgcg gcgaggtgat cctcgacgct
      121 ccggcctccg ccgtggcggg ccacgtccgc gacggaatcg tcgaggagca cgggcccgac
      181 cgctgccggg tggttctggg ggcctggtcg tggcccggcc tggccgccgg gctcggcagg
      241 ttcgacgtgg acatcgaggt ggtggggccc gacgagctca gggacgcctt cgccgatctg
      301 gcccgccgct tcgccgaagc ggcgggccag gggcacagcg gttccgcggg gcccggtgcc
      361 ccttaggggg cgccggtgag ctgggtgtcg gtcgtgtcgt cggtcgtcga ggcggtcaag
      421 gacgaggtga tgtgtccggc gaggccgagc accaggaaga ggacgacgag ccacttggcg
      481 gcgctgctca ggatcagcgg gcgcgtcgcc gaccgcgcct gctccggggg aacggcgaga
      541 gcgtcgtcgc cgaacaggcc cttggggtag gcgggggtga gcatcatgac gtacgcggag
      601 aagcgcatcc ggtagcgcag ggtggccgcc gtcgcctcga acagcggccg gggcatccgg
      661 ccgaggcaga gcgtgatcag ccaccagacg aaggccagcg cccaccaccc gtacacggcg
      721 aggctctgga cgatcgccgc cgggatcatc aggaagacgc ggaagagcac cgcgagccgg
      781 ttgagcgggg tgggccgcac ctcgatctgc accgggtagt cggcgggcgg ggtgagggcg
      841 aacggcgggt agcggtcgat gagcagcatg tcgctcgccg agacgcgcat gtcgtaaccg
      901 aggacaccgg tcaggaagcg gaagaccggg tcgggcagcc gccccagcac cagggcggcg
      961 aaccacccca cgatgacggt gaagaacgcc gcgatgtgca ggaagaacag cacgatgaag
     1021 tgcgggatca gcagcaggag tcgcaggagg acggtcagcc gccgctggcg tgccggttcg
     1081 acgatgtcca ggacgggcct gaactcgtcg gcgtccgcct ccttgcggcc cgggctccac
     1141 tggccttcgg ccatgtcgct cctcctcggc aggggatccg tacggcatcc gcacgcagga
     1201 cgtgtcccca ccgtgcgtcc ggtccgggcc gctcgcaaac ggcccggccc gaacgggtac
     1261 ccgggctcag cgcctgcgga ggcggtcgag gagggggcgg ggggccttgg cgccggcgga
     1321 cttcacgtcg gtggtcttct cggcggcgga cccggtgccc gtgcgcttgg cgcctgtgcc
     1381 cttggtacct gtgcgcttcg gcctcggtgc gggcccgggc ttgggctcgt cccgcggttc
     1441 cgaggagcgg ggaacgtcgg agtacgcgta atagcggtgg ctgatccggc ggccgagcac
     1501 gaagtacccg agcagtgcgc ccgccgtgtt gaggatgacg tcgtcgatgt cgaaggcgcg
     1561 cccctggacc agggctccct ggatcagctc gacgacggcc atcgcgacgg ccgtcagcag
     1621 cgtggtccgg atcatccgca ggcgccgtgg cacgaagaac ggcagcagga gtccgaacgg
     1681 cacgccgagc agcaggtttc cacccgcctg cttgcacgcg gcgaggaagg tgtagtcctc
     1741 ggcgtactgg cgcagcgagc gcccggggcg aaggttggcg gtgacgatgt cctcggaggc
     1801 cggcgagggg gtgagcgtca ccttggccag cagtacggag aacgccacca gtcccagcag
     1861 caccaccgac aggaccgccc cgcgcaccag tacacgtacc catgtcctct ggcgggcggg
     1921 gggattcgcc tctgctgtca tggcccacgg atgcccccgc ccggccggaa cacacgccga
     1981 agcgggcggc ggagcaaaat ctggtccggc cgtccgcgac cgcctgcgac gatgtgcgca
     2041 tgagcacaga gaagaagaag gacctgctgg acgaggccga ccggctgcgt gaggggggcc
     2101 ggcccgagga ggcgcgcgaa cggctgctcg ccctgacggc cgagtatccg gacgatgccg
     2161 aggtggcctg ccggacggcg tggatccacg acgtgctggg cctggagtcg gaggcggtgc
     2221 cgtactacga gcgtgctctt gccgacccgg agctatcggc ggaggaccgg cgcgggacgc
     2281 tgctggggct gggcagtacg tatcgagtcc tcggccggta cgggcagggg gtggagacgc
     2341 tgcgccgggg cgtggaggag tttccggacg acggtgcgat gcggacgttc ctggcgatgg
     2401 cgctgttcaa caccggcgag cacgacgagg cgatgcggct gttgctggag ctgacggccg
     2461 cgaccagcca ggacccgtac gtccagcagt accggcgggc gatcgagcac tacgccaagg
     2521 acctccacga gaccgtctga cccacgcggc ggccggggtc ggtggtgcgc ggcgcgccga
     2581 gggcgacgcg ccggtcgggg agcggcgcgt cgtcggggag ctgcgcgtgc cgagaatgct
     2641 cgggtgtcct ccgctccccc ggcgcttccg ccgtccccgc cttccgcctc ttcctccggc
     2701 gggtcccgga ccggtgacgc gccgtggggc ggcgaggcgg cgctgcttct gctgtccgcg
     2761 gcttccggcg cggcggacgc gttcgtcgcg gcggcggggg cgctgatggc cgggcggtgg
     2821 gggtaccggg tcccggcgct gctgggggtg gaggtggtcc tgctgggggc ggccgccgca
     2881 ctgtgggggc tggagctggt ctcgtcgtac ggggaccgac tcgggctgct gtctctggtg
     2941 gcagtggcga tgggagtgca ggggcgggtc cgggtgacgc cgacgaacta cttcaccggg
     3001 acgctgacct cgctcgccgg ccgcgtggcg ttgcgcaagc tgcggggcgg ggacggctgg
     3061 gtgctggggc ggctggccgc ggtggtggcg ggggccgcgg tcgcggcgct ggccgagcga
     3121 tggtggagcc ccggggccgc gctgggggcg gtggtgatgg ctgccggcgc gctggccctg
     3181 gagacggtct gggggcgggg cggccgattg cggccggaca ggaggaagcc ccggccggat
     3241 cgggggaatc cagccggggc ggcttgagtg cgggcgtgaa gggcggtcgc ctctcggcgg
     3301 ggggctccac ggggcttcgg cggtgccgat cgtccccatg ggctacaggt gaggcccggg
     3361 gacactgtcc ccctcacacc cacgtataga tgaacgataa accatcccgg ggtgttcccg
     3421 ggaatcagcc cccgcggatg tgatccacag cacggaattc ccggctcttc ccctggtcag
     3481 gccgcgttcg gtcagcttcc ggacgcctcg ccggtgccgt agcggcgccg gaactgctcg
     3541 acacggcccg ccgtgtcgag cacccgggtg ccaccggtgt agaacgggtg gctcgccgac
     3601 gaggtctcca cgtcgatgac ggggtaggtg ctgccgtcct cccacaccac gtgctcgccg
     3661 gagtcggcgg tcgaacgggt caagaaggcg acgtcggccg cgcggtcacg gaagaccacg
     3721 ggacgggaga cggggtggat acggggcttc atcgatgcgt tccttcctca ccgcccgtgg
     3781 cggtgccgta cagggtgagg ggccttctcc gtgcggtcag cggacctcgc ggaacaggac
     3841 gtggcgaccg acggccgagt cgaacttgcg gagctccagc cggtcggggt cattgcggcg
     3901 gttcttgcgt gtcacatagc tgcgacccgt tccggcggtg gaccggagag tgacgacggg
     3961 cctggactca ctgcgcgcca tgggcgcctc cttcgctgcc tccgacgacc cccagcccct
     4021 ctatcgggaa tgggattcat tttctttctg gtggggtaac gcaggtcggt cgcgcggcat
     4081 tcccgcccgc cccacaccct tcacctgtca cccgtgcgcc actcccacac catcggccct
     4141 cctcagggac cccagtcaac tcgccccaca cgcaagcctg ttcggacggg aaccatctcg
     4201 gccagccgct ggcatatgcc agaagcaact acgcatcgag tgtcgccaaa tcccttacgg
     4261 cccgccgcgg cctgtgcgac agtcggtagc ggtccccctt cggaaccggc taggccgcgc
     4321 ctgcaacgga gtacgagatg ccgtcccccc tcttcgcgga ccgccccgca ccacagcttc
     4381 ccgcgcacga cgccgtcgac gacttgatcc accggacgcg ccgactgcgc ggagatgtgg
     4441 acgccgtgcg gcgggacgcc gtcatgtccg acgaggacga cccgcagctg cgctggcagc
     4501 gcgccctgtg cgagctggcc gtgcaccacc tggacaccct cggcgagcat ctgggccagc
     4561 tcagggcggg tctgccgggc ccgcgcgccg gaggctccgc cccggggggc gaggaagccc
     4621 cgaaggaccc caaggccggt tccctgctga gccgggtggg cagcgccgag tggaacctcc
     4681 tcaccgacga gtccagctgg tccgaggagc tgtacgagat cttcggcagg ccgctcgact
     4741 ccgcccccct ctccctggac gacctgccgt ccgtgctgct gccggaggac cagccggtgc
     4801 tgaccgccat ggtgacgggc tgcctggtcg acggtcggcc gatggacggc gagttccgta
     4861 tcgtgcggcc cgacggcgac acgcgcacgc tgcacatgac gggcgagccg gtcctcgacg
     4921 ccgagggctg cacggcctcc atgtgggcgg tcctgcggga cgtcagcgag ctgcgccgca
     4981 gcgagcaggc cgtgaccagg agccgcgcgt cggtacagcg cgaggagcac atcgagcgcg
     5041 ccgagcaccg catggccgtg gagctccagg agaccgtcct gcccccgtgg cgcggatcac
     5101 tgcgcctccc gccgcagggc cccggcgccc tggacatcgc ggcgcactac ctcccctccg
     5161 cgtcgagcgg gctcatcggc ggcgactggt acgacgccat ggagctgccg gacggacgca
     5221 cgctcctcac cgtcggcgac ctcaccgggc acgggatccc cgccacctcg gcgatggcga
     5281 tgctgctggg cgcgctgcgg ggcatggccg tcgccggcat cgagccgggc gcgctgatgg
     5341 gacacctcaa ccaggtgctg gagacgacga tgcagcccgc gctgggcagt gccctgtgct
     5401 gccgcttcga ccccggaacc tccgttctct cctgggcgca ggccggtcat cccgcgccgc
     5461 tgctcttccg cggcggttcg gggcggctgc tgcccccgcc ggacgggata ctgctgggtg
     5521 ccgcgccgca ggccgtgttc gagcaggacg aggtacggct gttccccggc gacgtgctcg
     5581 ttctgcacac cgacgggctg acccgacgcg gcgaccgggg tgcgggcccg gaagcactgc
     5641 tcgccctcgc ccctcggttc gcagaggccc gtacggcaca ggagtgcgtg cggggcgtcg
     5701 tcgaggagtt cggcgggacc gagcgcctgg acgacgcgtg cgtgctggtc gcccgcatcg
     5761 gggcgtgagg gaacacggac ggatcagggc atgccgctga agcgcggacg cgtcagggtg
     5821 tgaaggagcg cggggcggcg cggtgggggc ggttcagatc tgcgcgcccc tggccttctt
     5881 ctggctcggc agcgacagct cgatctcctc gcgcagatcc tggatgcccg cgtatccggc
     5941 gaactggccg gtgagccggt acatctcacg gagccggtcc caggtccggt gcgaggaggt
     6001 ctcccccatc gacaccagcg cgagccgggc gtagcggtcg gcctgttccg ggtcgttggc
     6061 gatgaagcag gccgaggcga gcgagatgta gtcgaagatc ttcgaccgct ggcgcccgtt
     6121 gacccgcagc tccagcgcct gcttggcgtg gcgctgggcg atgatcgccg cccccgggtc
     6181 gtgctcggcg agcgtacgga aggcgagcgc ctgcatgccg tgcatatcgg cctcgtcgaa
     6241 catctgcatc caactgggcg gcgggacgtc gctcttgtcc gagacgaaga gttcctcggc
     6301 ctcgccgagg gtgcgtcgca tggcctggcc gcgccccatg gacgcctgtg cccaggcctc
     6361 gatggtgcgc agcatcgcct gcgtacgggg cagggtctcg tcgccggaac cggatttggc
     6421 gagcttcatc aggtcgagtg cgtcgtcggg gcggcccagg tgcaccatct ggcgcgccgc
     6481 ccgggagagc gcctctccgg cgcgcggccg gtcgccgccc tcgcgggccg catgggcggc
     6541 gatgacgaag tacttctggg cggtgggttc gaggccgacg tcgtgggaca tccagcccgc
     6601 caggacggcg aggttggcgg cgacgcccca caggcggcgc tggagatggt cggggtggcg
     6661 gtaggcgagc atgccgccca cctcgttgag ctggcccacg accgccttgc gctggagtcc
     6721 gccgccccgg gacgcgtccc aggcgcggaa gacctcgacc gaatgctcca gggcctcgat
     6781 ctcctcggag ccgaccggtg cggcctcgta ccggtcgaaa ccggcgggat cggcgtgcag
     6841 cgggtcgttg gtccgtggcg cgtcggccgc cggagcgggg tcgctgtgca gccagtcgta
     6901 catggggccg gcgatggttg agccggcggc gagcgcggcg cccgcaccca ccaagccgcg
     6961 tcggttgagc atgaggtcca ttcccgtgaa ttcggtgagg accgctgccg tccgttcggg
     7021 cgcccacggc agttgatcgg gattgttctc cgtcccggag tcacgccgtt tccccacacg
     7081 cccgcgtcgg ccgaacccga ggtcctcgat ggtcacgaca cggccgagcc gctcggtgaa
     7141 cagagctgcc agcacttcgg gcacgggatc acgcggggac tcccccatgt cgatccagcg
     7201 cctgacacgc gaggtgtcgg tggccagctg cgggtggccc atggccgccg cctgccggtt
     7261 caccattctc gcgagttcgc ccttggacca gccggccagg ccgaacaggt cactcagacg
     7321 ggtgttgggt tctccggtca cttcaagccc ccaggttctc ggctgacttg acactaaccc
     7381 cctgtcagat gcgctgtgac tattcgccag ggttcgccag ggtccgccag atggtctgcc
     7441 acccgtgacc cgttgtcagg taggagtgcg ccaccccgcc cggcagccct aggtactccc
     7501 cagggtgccg aacggccgtc ggccgggttg gcgcacgtac cttgtcggcg cacgaaggga
     7561 tctgtctcgc ccatgtacac agcatcgtcc tccgtgtccg ccccgccccg tccgctccgc
     7621 ccgatgggcg cgggcggcgg gccctatctc gctcctcacg ccggtgcgcc ggtgcagggt
     7681 ccgggccggg cccgacgggc cgcgggaccg ggcgccggac cgctcagcgg aaggatcgac
     7741 ctgtccgggc cgcagggcgc gcaggtgcgg atggccatcg cctccgtgca gcgcatctgc
     7801 cccgagttca acccggtcca ggtactgcgc cgcagcggac gttcggtcct gatcgtggga
     7861 acgaccgggc gggcgacggc cgtggcgaag tgtttactgg accactcgcc ggcgtggacc
     7921 gagcggttcc ggcacgaaat agcggcgtac cgcgcgttcg tccggcatcg gcccccggtt
     7981 cgggtgcccc ggctgatcgc ggcggatccg gagaactgca cgctggtgat cgagcggatg
     8041 cccggacggg tcgccgccct cacccggcat ccggcggagg cgccgccgcg ggccgacatc
     8101 cgggccgccc tgggcgcgat cgcccgggtg aacgcctggc ggccgccgcc cggactgttc
     8161 gaggcgccgc tcgactacgc ctcgcggatc gcccgctacc acgagctcgg actgttcacc
     8221 gaccgtgacc tcggtgacct ccagaagctg ttgcacggtc tggcccacgc gggcggccgg
     8281 cagggcatgg ggcagttctg ccacggggac gccctgctct ccaacatcct gctgtcgccg
     8341 accggaccgg tgctcgtcga ctgggagcac gccggctggt atctcccggg gtacgacctg
     8401 gcgacgctgt gggcggtgct gggtgacgcc ccggtggcgc gtcgccagat cagccagctg
     8461 gcccaggcca ggggcccggc cgcgcgggac gcgttcctgg tgaacctgat gctggtgctg
     8521 acccgcgaga tccggaacta cgagacggcg gtgcagcgca ccatgcggga ggcgcccgtg
     8581 gcgggcgcgg gggcggaccg cccgggtgcg ctctcctcgg gtgaggagca gcggctgctg
     8641 ctgcggaggc tgcacgacga ctgcgcgatg gcgcggaggg cggtgcgggc ggcggtcggc
     8701 acccgctgag gcgggacgac gccgacggac gaaagggcgg gcggagggcc tgcccgtcga
     8761 ggaccccagt gccccgtcgc tgtgggccca gaccactgtg aagaagaagc gcgctgcggg
     8821 accggtgccg acacaccggt cccgcagcgc gctgttctgc gttctgtgac cgtgtgctga
     8881 ccctgtgccg ttccggggcc cctcgcgggt gaggcccgcc acgagaccca cgtcacctac
     8941 gacgcccggt aggaggcccg agccctcccg tccggcgtaa cgaaccgccc atatggctca
     9001 taaattggca tctcacgatg aagcgtagta aaggcggtca ttgcttccta tgtcggtgcc
     9061 cgctaaccat ggatcccggc aggcaccgag ttcgagtccg cgtcgatcgc ccaccggcga
     9121 ccgcggcccg gacggtccgg tacccgccga cgcggcgcga aggccgcgaa gcccgtcccc
     9181 cataggaaga gctcacgcat gccccgcatc tccaccctgc gcatcacccg ctcgcacaag
     9241 atcgccaccg ctgtgctcgt cgcggccggt tccgtcaccg ccataaccgc caccggcggt
     9301 ccgagcgaag cgcagaccac cgcgacccgg tcctccgtct ccgtggagcc ggtcgccgcc
     9361 gcgggcatcc ccacagcgaa ggacgcggcc gagaaggccg cgaaggagaa cgccgccaag
     9421 gaagccgcag cgaagaaggc cgccgccaag gcgaccgcga agaaggccgc cgagaaggag
     9481 cgctccgaga agcaggccgc caaccggtcc accgagcgca aggccgtcac accgaagaag
     9541 tacgcgaaca acctcgacgg ctggatccgc gagtcgctcg acatcatgaa gaagaagaac
     9601 atccccggct cctacgaggg gctgcaccgc aacatcatgc gcgagtccag cggcaacccg
     9661 aacgccgtca acgactggga catcaacgcg cggaacggga tcccctccaa gggtctcctc
     9721 caggtgatcc agcccacctt cgacgcgtac cacgtcaagg gcaccccgaa gaacctcacc
     9781 gacccggtcg ccaacatcac cgccgccgcc aactacgccg cggaccggta cggctcgatc
     9841 gacaacgtcg actccgccta ctgagccgac acccccgacg cgccgatgat gtgactaatg
     9901 gccatcgtgc gtgccccgga tggccgaagg gtagtgctgc gcggacacca ccggtccgcg
     9961 cgattccccg cgcggaggct tctggaaagg cctgacgcac atggcacagc ccttctcact
    10021 gccggacttc tacgttccgt atccggcccg gctcaacccc catgtggaag cggcacgctc
    10081 gcacacccgg gagtgggccc gttccatggg gatgctggag ggatccggca tctgggagga
    10141 gaaggacctg gaggcgcacg actacgccct cctgtgcgcc tacacccatc ccgactgctc
    10201 ggcggaggcg ctcagcctcg tcaccgactg gtacgtgtgg gtcttcttct tcgacgacca
    10261 cttcctggaa ctgttcaagc gcacccccga ccgggcgggc ggcaagcggt atctggaccg
    10321 gctgcccgcc ttcatgccga tggagcgcgg agccgcgaca cccgagcccg agaaccccgt
    10381 agaggcgggg ctcgccgatc tgtgggcccg gacggtgccc gcgatgacgg acgactggcg
    10441 ggcccggttc gcggagtcga cggagaacct cctcaacgag tccctgtggg agctcgccaa
    10501 catccacgag ggccgcatcg cgaacccggt ggagtacatc gagatgcgcc gcaaggtggg
    10561 cggcgcgccc tggtccgcgg gcctggtcga gtacgcggcg aacgcggagg taccggcgtc
    10621 ggtcgccggg tcccggccgc tgcgggtgct gcgggacgcg ttctccgacg ccgtgcacct
    10681 gcgcaacgac ctcttctcct accagcgtga ggtggaggac gagggggaga acagcaacgg
    10741 cgtgctggtg ctggagaagt tcctcggctg ctccacccag gaggccgccg aggccgtcaa
    10801 cgatctgctg acctcacggc tccagcagtt cgagaacacc gccctcaccg aactcggccc
    10861 tctctgcgcc gagaaggccc tcgacccggc gcagaccgcg gccgtgctgg cgtacgccaa
    10921 ggggctccag gactggcagt ccggcggcca cgaatggcac atgcgttcca gccgctacat
    10981 gaacggcggt ggcgcgggcg aggccgtgcc cggcctgggc atgtccgccg cctccatcag
    11041 gttcaccctc cgctcggagg ccgcgcgggc gcgcagccac agccatgtgc cgtaccagca
    11101 cgtgggcccc tcgctcctcc ccgacttcga gctgcccttc accaccacgc tgagccccca
    11161 tctggaaggg gcccggggcc ggctcgtcga gtgggcacgg cggatgggca tcctggaggc
    11221 ccagccgggt gtgccgggtt cgcacatctg ggacgaggag cggatccgcg cgatcgacct
    11281 gccgctctgc gctgccggta tccacccgga cgcgagcccg gacgagctgg atctgtcctc
    11341 gggctggctg gcctggggga cgtacgggga cgactggttc ccggtggtgc acggacgggc
    11401 ccgggatctg gccggggcgc ggctggcgaa cgaccggctg tcgctgttca tgccgctgga
    11461 cgacgaggga acgccggagc cggtgaacgc gctggagcgg agtctgggcg acctgtggcg
    11521 caggaccgcc ggcccgatgg acagggacgc gcggcgcact ttccgtaccg cgatcgagac
    11581 gatgaccgag agctggctgt gggagctggc gaaccaggcg cagaaccgca tccccgatcc
    11641 ggtggactac atggagatgc gacgggcgac gttcggttcg gacctgacga tgagcctgtg
    11701 ccggctcggc catggccgga aggttccgga ggaggtctac cgcagtggtc cgatgcgttc
    11761 cctggagaac gcggcggcgg actacgcgtg tctgctcaac gacctgttct cgtaccagaa
    11821 ggagatcgag tacgagggtg aggtgcacaa cggcgccctg gtcgtgcaga acttcttcgg
    11881 cgtcgactat ccgacgggcg tggcgatcgt gcacgacctg atgaactcgc ggctgcggca
    11941 gttccggcat gtggccgagg tggagctccc ggtgctgtac gacgacttcg gcctggacgc
    12001 cgaggcgcgg gagatcctgg cgggctatgt gcgggagctg gagcactggc tggcgggcat
    12061 cctgatctgg caccggggct gccgccgcta ccgcgaggag gatctgcgga gcggtcacgc
    12121 cgcgccctgg catctcggcg gacccacggg gctcggcacg tcggcggcgc aggtgacccg
    12181 gatgatgacc ccgttggcgg gcagccgggg ctgacgcctc gggcctgtcg tcaccttccc
    12241 gtcgccgccc ggcaggcggg aaggcggcgg caggtccggg ccgtgcggcc gggcggacca
    12301 ggacgtgtct cggcacggcc tcgaacgatc ccgccctcgg aggtgtgccg gtcggcggtc
    12361 gctggaggag cagtccgtcg acgaccgatt ccagcgagca ggcggtgagc agagggtccg
    12421 ggggtcctgc cgtcggcgtc aagggaaaag gccgcccgga cggccccgga cggccttgcg
    12481 aagggacgtt tcagccttgc tggaacagct ccgcgggcag cggcttgagg agggtgtaga
    12541 ggtcgtcggt gatcggccgg tcccagctgg cgatggtcac gaggacgccg tcgctgcggt
    12601 cgaactggac gcaggcgatc cggctctcgg agagcttgac gcggcggacg atcagcaggt
    12661 tgtcgccctg catgacgggg acgtcctcgg agctgacgac ctcgatcggc tcgtcgttct
    12721 ccagggcgag gagcagttgg gccacctcga aggggacctg gccctcctcg gtctcgcggg
    12781 cgggcgagcc ttccggcagg ttaccgatga tcatcgccgg gccccgtccg ccgtacaggt
    12841 cgtagcggag gaagacgccc tggcagctgc cgtcgggggc ggggagcaga ccggcgccga
    12901 ggttgccggg ccagtccccg gggtccatgg ccaggacgtc gaagtccggg cccgcgggtg
    12961 ttgcggcgct acggcggcgg aggaaggaca tgcctgccat gttacgtgtc ccggctcacg
    13021 ttgcggagcc gggcccgggc cgcgcggggc cgggcccgtc gcgtcttctc agccgggcgg
    13081 gggctccgta cccaccagcc acatggcgaa gaactgggac cctccgccgt aggcgtggcc
    13141 gagcgcccgg gtggccgcgt cgatctggtg ctcgccggct ctcccccgga cccggagggc
    13201 cgcctcggcg aagcggatca tgccggaggg gccgatgggg ttggtggaca gcacgccgcc
    13261 cgaggggttg acggggaggt cgccgtccag ttcggtgacg cccgcctcgg tgagtttcca
    13321 gccctcgccc tcggcgaagc cgaggttctc cagccacatc ggctcgtacc aggagaacgg
    13381 gacgtacatc tccacggcgt cgatctcgcg gcgcgggtcg gtgatccggg cctgccggta
    13441 gacgtcggcg gcgcagtcct tcccggcccg cggagagacg aagtccttgc ccgcgaacag
    13501 ggtcggttcg ctgcgcatgg cccctccgtg gacccaggcg ggcgggtgcg gcgagcgggc
    13561 ggcgccgtcc cggccggtga ggatcatggc gcaggccccg tcggaggagg ggcaggtctc
    13621 ggagtagcgg accgggtccc agagcatggg cgaggactgg accttctcca gggtgaggtc
    13681 gtggtcgtgg atgtgcgcgt aggggttctt cagcgcgttg cggcggtcct tgtgtcgtcg
    13741 tgcatcgcaa gttcgtgccg gaggaagtgc tgcggacgat cgagaaggag aaggtcacca
    13801 gcgtgtcgct ggtcggcgac gcgatgctgc gcccggtgag ccgggccgca tcgcccagtg
    13861 cggacatgtg ccgctcggct actacaacga tccggccaag accgccgaca ccttcttcca
    13921 ccggggcgat gagcgctggg tgctgctggg cgacatggcg accgtggaca cggacggcat
    13981 cgtcacggtg ctcgggcggg gctcgcagtg catcaacacc gatggggaga aggtgtatcc
    14041 ggaggaggtc gagcaggcgc tcaaggcgca tgcggatgtg tacgacgcgc tcgtcgcggg
    14101 cgtccccgac gagcgctggg gaatccgggt cgccgccgtg gtccaactgc gcgagggtgc
    14161 ggctgtgttg accctggagg cggtgcagtc ccactgccgg ctccggctgg ccggctacaa
    14221 gatccccggc gcgctggtgc tcgccgaccg gatccagcgc tcgccgagcg gcaaggcgga
    14281 ccaccggtgg gcgaaggcgg tggtggcggg ggcccaccgg agctgaacga ccggagctga
    14341 acggccgagg ggccccgcct gccccgggcg ctgatcgtca aggccccgtc gccgatcgtc
    14401 aaggacagat cgggaagtga tccgcagact ggtgggtgtc gggtcgcccg gcgccgcggg
    14461 ggtgcgccgg gtgctcgacc ccacgtactc tcccacctgc gccttcatgt tcgaacggga
    14521 aagagatcac agtgagttcg ccgctgacac aggacgatcc ggagcgcatc ggggagtact
    14581 ggctcgccgc caggctgggg gccggcggac agggcgtggt gtacgaggcg tacgacgcgt
    14641 ccggagcccg gttcgcgctc aagacgctgc accgggccgc cgatccgttc ctgcgggagc
    14701 gtttcacacg ggaggcggag gcggcccggc gggtggcgcc gttctgcacg gcgcggatcg
    14761 tgcgcgcggg cgtcgacggc gaagtcccct atctggtcag cgagtacgtg gcggggccga
    14821 ccctcgccgc ctcggtacgg gagaacggga cgtcgtcccc ggacgcggtg ctgcggctgg
    14881 ccaccggggt ggcgaccgcg ctggccgcga tccaccaggc gggcgtcgtg caccgggatc
    14941 tcaagcccgg gaacgtcctg ctcggcccgg acgggccccg gatcatcgac ttcgggatcg
    15001 cccgcgcccc cgacatgtcc ctcaccgcca ccggcgcgat catgggaacg ttcggctaca
    15061 tggcccccga ggtcctggcc gggcagcggg ccaccgaggc gtccgacgtg ttcgcgtggg
    15121 ccgcggtcgt gctgtacgcg gcgaccggca cggagccgtt ccggggcgag aacatcgccg
    15181 aggtcgccca ccgcaccacc accgtcgagc cggatctggg agcgctgccc ccggaggtac
    15241 ggccgctcct ggccgcggcc ctcgccaagg atccggagct gcggcccacc gccgccgatc
    15301 tgctgctggg cctggtcggt gcgcccgtca aggcggcgga cccccgggcc gcgctgatgg
    15361 aagcgggcgc ccggaaggcc gccgcgcccg gggccgacgg accgatggcg accggcacgg
    15421 atggagcggg cagcggggac ggcgctggtg gcgtcggcgg gaccgtggtg gaggcgcccc
    15481 tcggcgagcg ggcagaggcg gcctacgcgg cgctctcccc cgccgcccag ctcgccgccc
    15541 acgggctgct gctccgcctc accgtgccgg gggccgcggc ggacggctcc caggactccg
    15601 tgcgtaccgc ccaccccgac gaactgctgg ccgaccggcc cgagggagag cagcaggagg
    15661 tcaccgccgc cgcccagcga ttgctggccg ccggggtcct cgcctcggag gcggacgggg
    15721 ctctgcgccc cgcgagcgcc gcgctgctgc ccgcgtggcg gcggctgcac gcctgggtcg
    15781 acgccgaccg gccgggcctc gccgtccttc agcgcatcgg cacggcggca cggctgtggc
    15841 agcgtcacgg cgagcggccg gaagacctgc tgcgcggcac cgagctgacc cggtgcctcg
    15901 actggctgcc caccgccccc tacagcctgc ggcccaaccc gctggagcag cgcttcctca
    15961 ccgcgagccg ggccaccgtg gcccgtacca cccggcgtcg gcggcagttg ctgtcggggc
    16021 tcgccggggc cacggcgctc gctctgctgg cgggtggcct ggcctggacc cagagccggg
    16081 aggccgaccg ccgccgggcc gaggccacgg cccgcgcggt ggcccgggcg gcggagaacc
    16141 tgccggccac ggagccggag accgcgatgc tcctgggcct cgcctcctgg cggatcgccg
    16201 aagtgccgga ggctcgggcc gccctcgccg ctgccgccgt ccagccagtg cgctcggtca
    16261 tcgacctgag cgacgtgaac gacggtgagg agcagtcgag ccacctctcc cgtgacggcc
    16321 ggcgtctgat cgcctcctcg tcgctgggtg tgcgcatcca cgatctggcg ggcgggcagg
    16381 cggccctgaa gaagccggtg gcgacccttt ctcccgagga attcgctctc gacgacacac
    16441 gacgcccggc gttcagcccg gacggccggc tcatgctcct ggtcgccgag gacggaacgt
    16501 tccgggtcat gaacaccgag gacggtactc cggccgcgcc cccggtccgg gcgccgtcgg
    16561 ggtacttcga gggagaggcc atatccaaca gcgggcacat gctcctgtcc gacggccgct
    16621 cgaccgccct ggccgaccgg gacggcaacg gactggcggt cgtgccccgc ggaagcacgc
    16681 tgacgcccga cggctcgtac tccgccggct gcgaaggcgg cgagctgcgc gtggcgggcc
    16741 tgctgcccgg ggaggccccg gtcatccgcg aggaactccc cgacaaggcc ggcccctgcg
    16801 gattcgagtt cagcccggac gggcggcaca tgtcggtgcg gatcggttcg accgcgaacc
    16861 tgtacgacct ggtcacccac aagaggaccg gctcgatgcg ccaccgcggc gacggcctcc
    16921 gcttcggctc acaggggcgt ttcctcgtcg gctggggaaa cgacggcacg accatcgacg
    16981 tgtgggcccg tggctcggag gaacccctgt tcacggtgac cgcgcccacc ggacagggtg
    17041 acaaggggat gtacgcccac caactcgccc tggacgagga ggcggagcgg ctgcgctact
    17101 tctcgaccac caccggccgg ctctacgaga tcgacctggc cggcgccctg tccggccggg
    17161 cggaccggcg cgtcaccgca gccgtgtcgg ccgggggccg gttcgggctg gtccggtccg
    17221 cgccgagctc ggtcgacccg ccgacgctcc aggcggtcga cctgcgcacc ggagagcccg
    17281 tgggcgacct cgtcgcgcag cgcgaggccg gcgacccgct ggagggcgag gagctgttcg
    17341 cctccatcga cgacgagggc cgcgtcatgg cgtactcgta ccgggaaagg gtctcccgct
    17401 acgagaccga cgacgaggtg gtcgtgcgcg acgtcaggga gggcaagaac ctccaccgcg
    17461 tccccgtcgc cgcgaaccac cgccctctgc atctcgccgt ctccccggac ggccgccatc
    17521 tctccctggt gtctcaggag ttcggggtga acagtgcgga ctcccacatc cacgaggtct
    17581 gggacatcga gaagcgcacg aagatacggc agttcaacga ccggaccgcg gaagccgtgt
    17641 tcagccacga cggcgaacgg ctggtgaccg ccgcggggac ggaggtcacc ttggccgacg
    17701 gggcggtgcg caagaccgga ctcgcccgcg atcccggtgg ccggccggtc ttctcccccg
    17761 acggtcgcta cctggcggtg ctcaaggagt ccggctggct ggagctgtgg gacggtgcgg
    17821 tacgcgaacg cgaggcggtg ctggcgagcg aactggtgcc gggcgcgacc aggttcgggc
    17881 agcccctcgg cgacctggcc ttctccgccg atggcagcct gctcgccgtg gccgttcggg
    17941 gcgaggcggt ccagctctgg gagacgagca cgaggacgcc cctcgggaac cccctgccca
    18001 tcacgggacg ccgggtggac gccctcgcgt tcgagggcac gcgcctgcgc actgtgacag
    18061 gctccgcggt ccacaggctg gacctctcgc cggaccggct ggcggagcag gtgtgccggc
    18121 gcgccgggcg cgacatcacc cctcaggagt ggcgtacgta cgtgcccgac gccccgtacc
    18181 ggagcctgtg ttgagcgggc gggccgaccg cccccgccgc tcagttcgca gactcgtcgc
    18241 tctcccggag cttggcgtac cggtagtcga cgggggacat cccgtgggcg gcgcggaaca
    18301 cccggctgaa gtgggccggt gatccgaagc cgcaccgcgc ggcgatcacg tggaccggtg
    18361 tgccggccag tccgggttcg gcgaggtccc gccgggcccg ctccaggcgg cggttgcgga
    18421 tgagggcggc taccgtggtt ccctcctgct ggaacagccg gtgcaggtgg cgggtggaga
    18481 tgtggtgcgc ggcggcgacg gccgcaggag tgagccgagg gtcgtggagg ttgccgccga
    18541 tgaaggagcg gatggccagg acgaggttgt ggctgcgggc ctccggtgac agggccgact
    18601 cctggtcgag cccgtcggcg agcacgccgg ccatgaggtc gagcaggacg cggtgcagcc
    18661 ggggtccgtc ggccggtccg tagacctccg tctggtccac caggtgcagg agtatctggg
    18721 agatcagcgc gccgaagccg tggcggccgg acaggcggcg gcccacgacg ccgtccaggg
    18781 acgtgctcgg cggcaggggc agctgcgacc gggggaggtc gaggccgata cccctgatgg
    18841 gggcgtcgac ggtcgccacc tcatagggct tcgaggtgtc gatgaagtag atgtcgtccg
    18901 gtgcgacagc gctgcgcacc gtgccctgtt cgacctggac ggacccgctg ccgggctgaa
    18961 cgagcgtcat gtggagcagc tccgggtcgg acttccggat cagccggggg gtgcgccggt
    19021 aacgggaggc gggcgcccgg gtgggccaca gcgccgcgtc ctcgatgcgc aggagccggt
    19081 actcggcccg gaagtcgtgg gcgtaggggc tgctgatctc catgggcgcg acgacgtcgg
    19141 ccatgtacgt gtgccagtag gcgaaccggt caccccgcgg catcgtgtcg gtccggaacc
    19201 ttcccgcgct cagcatgcgt cgccgcctcc ttcccgcccg tggagcccga acgcccggat
    19261 ggccgcgagg aattccctgg gccggtccgt gtggatcagg tgtccggcgt cgacggtgac
    19321 cagctcggcg tccggtatcg cgcggaccat ccgtgcgagc tgttcctggt cgatgtggct
    19381 gtcgggcccg ccgccgatga cgagggtggg gacggtgatc tccgggaagc gttcccggac
    19441 ggccgggtcg ggatcgttca gctgcgcgtc ggtgtcggga acgacgggcc agtcgaagtc
    19501 gaggtcgccg tcggggcgga cggcgggcgg gcggggcggg tcgagcggga ggaggggcgg
    19561 cgcgtcctcg atgatcaggc gcccgatcag gcccggttcc cgctgggcca gcaggtaggc
    19621 ggcgaccccg cccatggagt gcccgacgac ggtcgctccg gcgaggttgc gggcttccag
    19681 gaaggcgtgc aggtcgtcgc ggaacatctc gaaggagtag cggccgggcc agtcgctcag
    19741 tccgtggccg cggaagtcgg gggcgtacac gcggtggtcg gcggccaggt cccgcgcgat
    19801 ccgggtccag gtctcgccgg agcccgtccg gccgtgcagc aggacgacgg gcggggcgtc
    19861 gggggcgccc cacacccggt aggagagccg gaccccgccc gcctggacgc tcaggatctc
    19921 cgggtcgagg aaggcctcca ccgtacgggc gaaggccccc gggtcgtcca gccacgggaa
    19981 gtgccccgcg ccgcgctgga cgacgaactc ggcgccaggg aagagcgcgg cgagctccgc
    20041 ggcccggtcc gggccggggt ggccgtcgta ctccccggcc aggacgagga ccggcacggt
    20101 cacctcgcgc agggcggcgg cggtggcggc ggggtcgaag gccccttccc ccgggtagcg
    20161 ttggcgggct tccgcgttgg tctggccggc ggaggcctcg gcgtgggcgc gggccgcctc
    20221 gtcccagcgg ccgtaggtga ggggccggac ggcgggccac agctcggcga acggtcctcc
    20281 ggcgagcagc gcctcctggg cggcccgtgc ctcggggtac cagggctcgc cgcgccgcag
    20341 ttcggcggcc tcgcgcaggt cgtcgtcggt cacttcgatg ccgacggccc gggtgctggg
    20401 ggtgacgagg gtcagggtgc gcagccgctc cgggtgccgg gccgcgtaca ggagggcgag
    20461 gtcggctccg gcggagtgcg ccagcaggtc gacgcgctcc aggcccaggt gttcgcgcag
    20521 ggcttccacg tcgtcgacga gacggtcgca acggtacgtc gaggggtcct cgggcacacc
    20581 ggacgcgccg gttccgcgca ggtccagcag gatgaggcgg cgccgcgcgg cgagccctcc
    20641 gaggtccccg agatacgcgc tcgcccgcat cggcccgccg ggcaggcaga tgagcggttc
    20701 cccctccccc accggatgcc aggcgagcgg ggtcgtgtcg tacgcggaga aggtcggcat
    20761 acgccccatc caaacaggaa gccgtgggcg agcacagcgg acttcgcggg gagctgatcc
    20821 acagcgatgt gtgcgctcct cttgccagcg cccccgacct cctgaattac tgctcccagg
    20881 aagatcgacc gaatgatcgg tcgcccgctt cgggagagga agggtcctta tgacggcgat
    20941 gctggacgcg gcggaacagc tcggccgggg cgagctggag gccctgcaac tggagcggct
    21001 gcgaaccacc ctgcggcacg cctacgacaa cgttcctttc taccggaacg ccttcgaccg
    21061 cgcggggctg aagcccgagg actgccgtgc gctcgccgat ctggcccgtt tcccgttcac
    21121 cgcgaagacg gatctgcggg acaactaccc cttcgggatg ttcgccgtac cggagcacga
    21181 ggtgcgccgg atccacgcct ccagcggcac gacgggccgg ccgacggtcg tcgggtacac
    21241 cgaacgggat ctggacacct gggcggacgt ggtggcccgg tcgatccggg cggcgggcgg
    21301 ccgggccggc cacaaggtcc atgtggcgta cgggtacggg ctgttcaccg gtggtctcgg
    21361 ggcgcattac ggggcggagc ggctgggctg cacggtgatc ccggcctccg ggggcatgac
    21421 cgcgcggcag gtccagctga tccaggactt ccggcccgag atcatcatga tcacgccgtc
    21481 ctacatgctg acgctgctgg acgagttcga gcggcagggg gtcgatccgc gttcgacgtc
    21541 cctgaaggtg gggatcttcg gcgcggagcc gtggaccgag gggatgcgcc gggagatcga
    21601 ggatcggttc gcgatcgacg cggtggacat ttacgggctc tcggaggtga tgggcccggg
    21661 ggtggcgcag gagtgcgtgg agacgaagga cggcctgcac gtctgggagg accacttcta
    21721 tccggaggtc gtggacccgt tcaccggtga ggtgctgccc gacggtgagg agggggagct
    21781 ggtcttcacg tcgctgacca aggaggcgat gccggtgatc cgttatcgga cccgggacct
    21841 gacgcggctg ctgccgggga cggcgcggac gttccggcgg atggagaagg tcaccggccg
    21901 cagcgacgac atggtgatcc tgcgcggggt gaacctcttc cccacccaga tcgaggagat
    21961 cgtgctccgt acgcccgccg tcgccccgca cttccagctg cggctgaccc gggacgggcg
    22021 gctggacgcg ctgacggtcc tcgcggaggc gcgggcggac gcgacggccg acgaacggga
    22081 gagggcggcg cggggcatcg cggcggcggt gaaggacggc gtcggggtga cggtgaacgt
    22141 cgaggtcgtg gacccggaga cgctggagcg ctcggtgggc aagatccggc ggatcgtgga
    22201 cctgcgggag aagg
//
