LOCUS       NZ_BMSZ01000003        22372 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces badius strain JCM 4350 sequence03, whole genome shotgun
            sequence.
ACCESSION   NZ_BMSZ01000003
VERSION     NZ_BMSZ01000003.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces badius
  ORGANISM  Streptomyces badius
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 550873)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: BGI assembly pipeline
            Genome Coverage                   :: 154X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014649415.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 03:57:07
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,894
            CDSs (total)                      :: 6,825
            Genes (coding)                    :: 6,582
            CDSs (with protein)               :: 6,582
            Genes (RNA)                       :: 69
            rRNAs                             :: 2 (23S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 244
            CDSs (without protein)            :: 243
            Pseudo Genes (ambiguous residues) :: 0 of 244
            Pseudo Genes (frameshifted)       :: 70 of 244
            Pseudo Genes (incomplete)         :: 206 of 244
            Pseudo Genes (internal stop)      :: 7 of 244
            Pseudo Genes (multiple problems)  :: 38 of 244
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:11:55
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 323554
            Orig. end                         :: 345926
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMSZ01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22372
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="3"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22372
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22372
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[<10000:12372](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<10001..12372)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    complement(61..74)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.51"
                     /tool="antismash"
     misc_feature    62..75
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     misc_feature    711..725
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.11"
                     /tool="antismash"
     misc_feature    complement(772..787)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.84"
                     /tool="antismash"
     gene            897..1364
                     /locus_tag="IE135_RS07510"
                     /old_locus_tag="GCM10010253_15200"
     CDS             897..1364
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127370.1"
                     /locus_tag="IE135_RS07510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_15200"
                     /product="ATP-binding protein"
                     /protein_id="WP_128818514.1"
                     /transl_table=11
                     /translation="MSLPLTRRIARAALLIAAGATPVVGAAGAASAADLPAAPELGGLT
                     ALDGANAGDTLDSAARQGTQAAGETGGRLVGTALPAAGETVGKSAKVAVPAAQETAGQA
                     AGNAGQAVGGVAEAAGGGLPTDGLGEGLPTDSLGKGGLPTDALPLNGLPIG"
     gene            complement(1498..2592)
                     /gene="dapC"
                     /locus_tag="IE135_RS07515"
                     /old_locus_tag="GCM10010253_15210"
     CDS             complement(1498..2592)
                     /EC_number="2.6.1.17"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (29-363). E-value: 4e-46.
                     Score: 149.7. Matches aSDomain:
                     nrpspksdomains_IE135_RS07515_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="dapC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010984558.1"
                     /locus_tag="IE135_RS07515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_15210"
                     /product="succinyldiaminopimelate transaminase"
                     /protein_id="WP_069743481.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 3e-45, bitscore:
                     149.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAVSSRLPVFPWDKLAPYKSTAQAHPDGIVDLSVGTPVDPVPEL
                     IQRALVAAADSPGYPTVWGTEALRDALTGWVERRLGAVGVSHANVLPVVGSKELVAWLP
                     TQLGLGAGDKVAYPRLAYPTYEVGARLCGAEPVVYDDPTELDPAGLKLLWLNSPSNPTG
                     KVLSKDELTRIVAWAREHGVLVFSDECYLELGWDAEPVSVLHPDVCGGHYDGIVAVHSL
                     SKRSNLAGYRAAFIAGDAAVLGELLLIRKHGGMMTPAPVQAATVAALGDDVHVSEQRAR
                     YADRRLALRGALEAHGFRVEHSEASLYLWATRDEPCWDTVAYLAERGILVAPGDFYGPA
                     GASFVRVAFTATDERVAAAVKRLS"
     aSDomain        complement(1504..2505)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE135_RS07515_Aminotran_1_2.1"
                     /evalue="4.00E-46"
                     /label="IE135_RS07515_Aminotran_1_2.1"
                     /locus_tag="IE135_RS07515"
                     /protein_end="363"
                     /protein_start="29"
                     /score="149.7"
                     /tool="antismash"
                     /translation="IVDLSVGTPVDPVPELIQRALVAAADSPGYPTVWGTEALRDALTG
                     WVERRLGAVGVSHANVLPVVGSKELVAWLPTQLGLGAGDKVAYPRLAYPTYEVGARLCG
                     AEPVVYDDPTELDPAGLKLLWLNSPSNPTGKVLSKDELTRIVAWAREHGVLVFSDECYL
                     ELGWDAEPVSVLHPDVCGGHYDGIVAVHSLSKRSNLAGYRAAFIAGDAAVLGELLLIRK
                     HGGMMTPAPVQAATVAALGDDVHVSEQRARYADRRLALRGALEAHGFRVEHSEASLYLW
                     ATRDEPCWDTVAYLAERGILVAPGDFYGPAGASFVRVAFTATDERVAAAVKRL"
     gene            complement(2699..3019)
                     /gene="fdxA"
                     /locus_tag="IE135_RS07520"
                     /old_locus_tag="GCM10010253_15220"
     CDS             complement(2699..3019)
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fdxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004950253.1"
                     /locus_tag="IE135_RS07520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_15220"
                     /product="ferredoxin"
                     /protein_id="WP_007446848.1"
                     /transl_table=11
                     /translation="MTYVIAQPCVDVKDKACIEECPVDCIYEGQRSLYIHPDECVDCGA
                     CEPVCPVEAIFYEDDTPEEWKDYYKANVEFFDDLGSPGGASKLGLIERDHAFIAGLPPQ
                     NQ"
     gene            3137..4132
                     /locus_tag="IE135_RS07525"
                     /old_locus_tag="GCM10010253_15230"
     CDS             3137..4132
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061638.1"
                     /locus_tag="IE135_RS07525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_15230"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_199887760.1"
                     /transl_table=11
                     /translation="MEFTIGGRLEVRITPADVGKRVSVRRRTNSGGTGVEFTDVVGVLT
                     SWNDGVMAITRRGGESVHIVESSLVAGKVVPAAPARRRGPAASFEELAAVTARAWQPVE
                     NETLGDWRLRAAGGFTRRANSALPLGDPGLPLGEALGRVRRWYEERGLPAYVQTATGAE
                     GTQELLCAELEGHGWRREVSAEVRIAALAPVGDREAEVSAVRLTREPDAAWLARYQRFS
                     TPGPHVLRVLGSGPSVWFATVPGSGDAPDAIGRCVVDGRWAGFMAVEVAPEQRRRGLAT
                     AVMAALAGRALDEGASAAWLQVEEDNEGARALYDGMGFAGHHRYHHYRSA"
     gene            4233..5114
                     /locus_tag="IE135_RS07530"
                     /old_locus_tag="GCM10010253_15240"
     CDS             4233..5114
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956285.1"
                     /locus_tag="IE135_RS07530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_15240"
                     /product="transglutaminase-like domain-containing protein"
                     /protein_id="WP_069743483.1"
                     /transl_table=11
                     /translation="MSGLDSGAADRRRQFAEEARSERPDLALLCLLLGAEAGPVGPAEV
                     VPVTPGEPVPDPYGFDAAQIELDRLAGLLPHGSRSPADWASALAELLGERCGFGGSSAD
                     YQRLDSSLLQQVLRRRRGLPILLSVVWIEVARRAGAPVCGVALPGHFVVGFGDLEHLVL
                     ADPFAGGAPLSDRDAELLVRGATGAPLEPSMMVPARPLEIVLRILNNIRAWAAARPERT
                     DVALWAVELSLLLPSHPARLRYEHAQLLVQRGEFLRGAAEMEEYAEVLAGIEPTAAENI
                     RRKARAARALLN"
     misc_feature    5158..5172
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 17.94"
                     /tool="antismash"
     misc_feature    complement(5253..5268)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.41"
                     /tool="antismash"
     misc_feature    5318..5333
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.69"
                     /tool="antismash"
     gene            5418..6023
                     /locus_tag="IE135_RS07535"
                     /old_locus_tag="GCM10010253_15250"
     CDS             5418..6023
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127364.1"
                     /locus_tag="IE135_RS07535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_15250"
                     /product="response regulator transcription factor"
                     /protein_id="WP_069740223.1"
                     /transl_table=11
                     /translation="MTTVLLVHTVPLWRASLASLLGTGRGIEVRTAERGAIQAALHGTG
                     PDVLLTDLDCPGARDVLAEVKTATAPHGGTYPLAVLTCSDQPRGLRRAYEAGALGYIDK
                     YRPVDDLSEVMHKLADGGRHIDESLAFSLLQVADMPLSPRELSVLSMAEEGDNVAGIAA
                     RLHLTPGTVRNYLAAAIRKSGARNRLDAIRRAKEAGWI"
     misc_feature    5838..5840
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(5992..7863)
                     /locus_tag="IE135_RS07540"
                     /old_locus_tag="GCM10010253_15260"
     CDS             complement(5992..7863)
                     /EC_number="7.-.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061641.1"
                     /locus_tag="IE135_RS07540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_15260"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_199887761.1"
                     /transl_table=11
                     /translation="MKPGHAPARPARDTALRRVAREARPFLRARTGAILRLAGWSLLEF
                     AQTFLSGYGVARALDDGFLAGRPASGLLWLAVAAVAVLPSVLAARGVFGRLADLVEPLR
                     DGLVRRAVARALSGALGGSGDVSTRSLSQVTHQSEIARDGWAGLVLTLRSFVFTAAGAV
                     TGLLALSPALLLIVLPPLVLGAALFLGTLPPMAARQRAYLAADEAYAAHAGELAASVRD
                     IAAAGTAERTVAESRALADTQLAASRSLARWSAVRVVALAVCGRFPPLLLLLGAPWLLR
                     NGLTPGGLVGALTYLTQALAPAVQALMTMLGTAGGRLVVVLDRFTDAPPPPAEEPAPAT
                     SHEDPSPPPRPDRDAPVAELHAVTFAYGPRAHPVLDRLSLTVGAGEHLAVVGPSGSGKS
                     TLAAVLAGTERPTGGAVGGRGRPARPADATAVRVLLPQHAYVFSGTLRDNLRYLRPDAR
                     DQEIAAMADAVGLDALLSRLGSLDAAVEPGRLSQGERQLVALGRAYLAAPPLLILDEAT
                     SRLDPAAETRAELAFAALPGALVVVAHRLSSARRADRTLVMDGPRTRCGTPAELLRSSA
                     LYRDLSGLWEPEGPQGPRPEERGARRHERRRDDERGIVRSTPPPSPV"
     gene            complement(7860..9725)
                     /locus_tag="IE135_RS07545"
                     /old_locus_tag="GCM10010253_15270"
     CDS             complement(7860..9725)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010272357.1"
                     /locus_tag="IE135_RS07545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_15270"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_199887762.1"
                     /transl_table=11
                     /translation="MPLPPPDPSPGEASGVRRLARLHPAALTWLFLCSTGGALAALALP
                     AALGHTVDRLVSGGPVPWSGLLLCAALTLAETGFDAAAAVTGTTTTARLTASLRTRTAA
                     RILAAEPRRALALPTGDLTARLTARTADAASAPVTAAGAVAGVLLPLGALVGLFLIDVW
                     TAAALLLGAPLLVALLRTFTRHTADAGADYQRAQSLIAHRLTEALEGADTIRAARTGAR
                     EHRRVLEPLAALADHGRRTWTVYGRAVGRSGLLLPLLMLLVLAVAGLRLAAGAIGVGDL
                     VAASRYASLAVGIGALTGALGSLARSRAAARSLDPLLTLAPLPHRGLGPVLDAPGHLEL
                     RDVGVAQDGHPLLTGVHLTVPGGTSLAVVGRSGSGKSQLAAVAGRLLDPDTGSVLLDGV
                     PLDAMEPARLRREVAYAFARPALLGTTVEDTIAHGPWTASSDAVREAARAARADGFLAL
                     LPYGYATPVADAPLSGGERQRLGLARAFAHPGRLLILDDALSSLDTVTEHHVRRALDAR
                     AGQCTRIIVAHRLSSAARADRVAWLEDGRLRATGRHDELWQDPDYRAVFSTGSSGTGSS
                     GTGGTTAAGSSGADATAAATATGTDTTATGTDTTAPSPLAAAETR"
     gene            complement(9822..9953)
                     /locus_tag="IE135_RS07550"
                     /old_locus_tag="GCM10010253_15280"
     CDS             complement(9822..9953)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611153.1"
                     /locus_tag="IE135_RS07550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_15280"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_003966507.1"
                     /transl_table=11
                     /translation="MALLDLQAMDTPAEDSFGELATGSQVSLLVCEYSSLSVVLCTP"
     CDS_motif       complement(9888..9953)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MALLDLQAMDTPAEDSFGELAT"
                     /locus_tag="IE135_RS07550_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9822..9887)
                     /prepeptide="core"
                     /locus_tag="IE135_RS07550_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="31.80"
                     /molecular_weight="2076.4"
                     /monoisotopic_mass="2075.1"
                     /core_sequence="GSQVSLLVCEYSSLSVVLCTP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MALLDLQAMDTPAEDSFGELAT"
                     /leader_location="[9887:9953](-)"
                     /alternative_weights="2094.4"
                     /alternative_weights="2112.4"
                     /alternative_weights="2130.5"
                     /alternative_weights="2148.5"
     gene            complement(<10001..>12372)
                     /gene="lanKC"
                     /locus_tag="IE135_RS07555"
                     /old_locus_tag="GCM10010253_15290"
                     /pseudo=""
     CDS             complement(<10001..12372)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446862.1"
                     /locus_tag="IE135_RS07555"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="GCM10010253_15290"
                     /product="class III lanthionine synthetase LanKC"
                     /pseudo=""
                     /sec_met_domain="micKC (E-value: 4.1e-210, bitscore: 694.7,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 2.8e-13, bitscore: 44.7,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 7.5e-06, bitscore:
                     19.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHRLAFKCVPNAGLLALRNAKYADRAGSGKFITVYPPSEEAFPE
                     VCTALMQLLEGEHGPYILSDLRCGNGPVHTRYGAFAARFCSGPDGRPVPAVADPRGRLV
                     PDDRGPAFRVPSWVTPPGFLTPHLEARAAVGLADLPYTVEKALHFSNGGGVYLGRDTRT
                     GEQVVLKEARPYAGLAADGADAVARLERERTALEHLAGLDCVPAVRDVFQVGDHHFLVL
                     QYIPGTTLNTVFARRFPLARQHPSAELLAEHAAWAEELYGQVERAVAAVHDRGIVISDL
                     HMSNVMVDEEAGRIVLLDFEAASPAAERRRQIVANPAFVAPPDRRGTDIDRYALACLRL
                     ALYLPLTTLFGIDRTKAAGLARDIARAFPVTEDALRPAVEEILRDVRDAGEAASRTAPA
                     AARGTAFAAGLRDWPRARDTLARAITASCTPERDDRCFPGDIAQFATATGGQSFAYGAA
                     GVLYALHETGAPPCAPAEDWLLRHAKDPASGSPLGFYDGLTGIAWTLHRIGRTAEAADL
                     LRIILDQPLEGLAPGLHNGYAGIGLALDDLARTASAADAPALSTAAAGCTALAVRALVD
                     GPPSPRTGLLHGASGIALLLIRRYATTGDTALLDLAATALRRDLERCRAGDDGALLVVE
                     GKRLMPYVGSGSAGIAAVIDAYLAQRPDPELAAAGRALLPAAFSAFYVQPGLLRGSAGL
                     LLHLAATPLCDPADRRRAVDRHTDLLGSHALPYGGGLAFPGEQLMRLSMDLATGTAGAL
                     LALGAASGRPTGLPFLPAAPAAQPAATAAPRTGPSRG"
     assembly_gap    12373..12410
                     /estimated_length=38
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<12411..12599)
                     /locus_tag="IE135_RS33910"
     CDS             complement(<12411..12599)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003962284.1"
                     /locus_tag="IE135_RS33910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_234427772.1"
                     /transl_table=11
                     /translation="MNPEYAAYCQADRRFYDAPHRSPGPDDGTVDEEKAYYAAVRGSAP
                     EGWTRSRRGDWLAYHPDG"
     misc_feature    12644..12656
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.27"
                     /tool="antismash"
     gene            complement(12818..13795)
                     /locus_tag="IE135_RS07560"
                     /old_locus_tag="GCM10010253_15300"
     CDS             complement(12818..13795)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611151.1"
                     /locus_tag="IE135_RS07560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_15300"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_069740237.1"
                     /transl_table=11
                     /translation="MGWWQVSADTLAGSRFVVSPLAEAVASLLLLERATAAHPGERAWL
                     EAHLPAYRRRAADDPVSALVIRSALAPRWTADFLTPAPVPVPPGQTPPSFAEELARVRA
                     TPPDRARADLEEALGGPLPAALDRDDLAERAADALEWVWTHTVLPDWPRRRRILEADVI
                     ARTAQLGRAGWAGALNGMRPGIRWLGGSRLQINTYDNPPRELDRAQLLFIPVTPDQSWV
                     CWDIPHRYGLVYPCSGVLAEAGRVSAPTALGALIGPARAAVLLLLASPLSTTQLVALTG
                     QGLGSVGRHLRILLDAGLVRRRRAGRSVLYFRTEAGDALVHGAG"
     gene            14030..15283
                     /locus_tag="IE135_RS07565"
                     /old_locus_tag="GCM10010253_15310"
     CDS             14030..15283
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127359.1"
                     /locus_tag="IE135_RS07565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_15310"
                     /product="MFS transporter"
                     /protein_id="WP_199887763.1"
                     /transl_table=11
                     /translation="MRTYRELFRTPEFTPFFAAVSVQTAAQTATGLALGTLVYARTGSP
                     LLSALAMFGPSLAQVAGALTLLSAADRLPPRAALTALALLSAGAACVQALPGLPLGVAF
                     AVLLVVGVAASPGGGVRYGLLNEIVPREGFLLGRSVLNMAGGAMQICGFAVGGALVAGF
                     SARGTLLIGAALYVVAAAVTRFGLTARPPRATGRPSVRETWRTNALLWSSTPRRYVFLA
                     LWVPNGLVVGCESLYVAYAPGHAGLLFAGGALGMLAGDTLVGRFVTTRWRARLGAPLRL
                     LLAAPYLLFAVRPGLPLALALVVVASVGFAASLLLQERLLALTPPELSGQALGLSSSGM
                     LAMQGAGAAVAGGIAQLTSPATGMAAVAGLSVVVTLALAPGLRTSPGADGGRLLGADGS
                     PRASRTPRTTHPAPEETT"
     gene            15280..15864
                     /locus_tag="IE135_RS07570"
                     /old_locus_tag="GCM10010253_15320"
     CDS             15280..15864
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Mac"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156: Chloramphenicol acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956278.1"
                     /locus_tag="IE135_RS07570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_15320"
                     /product="sugar O-acetyltransferase"
                     /protein_id="WP_069740220.1"
                     /sec_met_domain="Mac (E-value: 1.2e-17, bitscore: 58.8,
                     seeds: 568, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDETRRSQKEAMLAGEPYLADDPELAAEALHAAVLSERYNATSA
                     ADPEARRAVLAELLGKVGEGVEVRPPLRVDYGYRTTIGPRTFINFGAVLLDVARITIGA
                     DVQMGPNVQLLTPTHPIDPEQRRAKWEAAEPITIGDNVWLGGGVVVCPGVTIGENTVVG
                     AGAVVTRDLPANVVAVGNPARVIRTIGEPEA"
     gene            complement(15907..16413)
                     /locus_tag="IE135_RS07575"
     CDS             complement(15907..16413)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446870.1"
                     /locus_tag="IE135_RS07575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4265 domain-containing protein"
                     /protein_id="WP_199887764.1"
                     /transl_table=11
                     /translation="MSSPACPERPSREADQIKVWFRLPPREDGPLPYETEGLWATRLGP
                     DTARVDNAPFLRDGLAEGETVRFRTDGDGVHWAGERVADSGNCTVRVLPVPDGPLGRDV
                     RAVHERLAGFGLTGEVFSADFPLVALTVPGGADLRGVKALLTRGRDEGWWHFEVSCVTD
                     AWRAA"
     assembly_gap    16554..16615
                     /estimated_length=62
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<16616..18823)
                     /locus_tag="IE135_RS07580"
                     /old_locus_tag="GCM10010253_15330"
     CDS             complement(<16616..18823)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012379171.1"
                     /locus_tag="IE135_RS07580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_15330"
                     /product="hypothetical protein"
                     /protein_id="WP_199887765.1"
                     /transl_table=11
                     /translation="MSRETDSSSSGPQGRGGAAYPSGTPPYGSRQYPSLHPSQDGSDEN
                     PESVDPPRPEEPKTETTLTTRIRINIPGSRPIPPVVMRTPMAESDISGGGRSDAERTGA
                     TPRPGTPPAAPGTGASAGAGTGPSDRSGGPGSGSNGGAPADRSRDGGPAADPTPAEKPA
                     REKSGSDWFAPRKAPTAGPATAGQGGPGAPGGPGGAGGPGGQSGPGGARGPGAGGPGSG
                     GPGGPGGPGGASDGGAGPSRPDLPYFSDAPKSGGGPGAPGSGPGRSALDSYGTEPPGGG
                     PRATPGPGMRTPGPSGPTTGPATGASSLTPNLDGVPGLGGPGPMVPGTPGGVPPRMSDD
                     TAILTPQAPAPEPGPGGHVSGDTLTSGIPVVPSEPRTPFPGGPGTPGAPVTGHGGPGGP
                     GVPTPGPTAPRPASQTASAPAAPAKKGRSKLVLLGVAAVVLLGIAYGAGLLLNHAEVPK
                     GTTVLGVDIGGGTKEEAVTKLEAALGERAKTPLTLSVDGKEEKLDPEKAGLTLDSQETV
                     RGAAGSDYNPVSVIGSLFGGERPADPVIPVDEEKLGVALTDLAGASGSANDGTIRFEPN
                     KAVAVPGKPGKTLDAGQSLISVRDAYRAQVQTGQAKVVELPVTTSEPTITQAELNRAMK
                     EFAEPAMSDLITIKAGPKQIQFGPARSLPQILSMKPVDGRLVDVYDKKAIETLLDGVFD
                     GIMAVKADGKKHQVGPDDVAQAMKTALTGKTPAERTVTINLT"
     gene            complement(18999..19472)
                     /locus_tag="IE135_RS07585"
                     /old_locus_tag="GCM10010253_15340"
     CDS             complement(18999..19472)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956268.1"
                     /locus_tag="IE135_RS07585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_15340"
                     /product="DUF6113 family protein"
                     /protein_id="WP_069743487.1"
                     /transl_table=11
                     /translation="MSDAPKKARGRADSSHAPRRNAPPREPAPIGFAARPNPARIAAHL
                     GLAVLGALVALAGTLVQAAWFPGGLIIALLGSAGLFYGGRILTRTQIGALAPAGGWFIT
                     VFLLLSGRPEGDYVFGDELGLVLFMLGGTAVAVICATTSKVPQSAIHSGRSGT"
     gene            complement(19469..20386)
                     /gene="mshB"
                     /locus_tag="IE135_RS07590"
                     /old_locus_tag="GCM10010253_15350"
     CDS             complement(19469..20386)
                     /EC_number="3.5.1.103"
                     /GO_function="GO:0035595 - N-acetylglucosaminylinositol
                     deacetylase activity [Evidence IEA]"
                     /GO_process="GO:0010125 - mycothiol biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="mshB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010063246.1"
                     /locus_tag="IE135_RS07590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_15350"
                     /product="N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-
                     D-glucopyranoside deacetylase"
                     /protein_id="WP_199887766.1"
                     /sec_met_domain="PIG-L (E-value: 2.1e-28, bitscore: 94.5,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDLPARRLLLVHAHPDDESINNGATMARYAAEGAHVTLVTCTLG
                     EEGEVIPPSLARLTADRDDALGAHRIGELAAAMRELGITDHRFLGGAGRYRDSGMMGAE
                     QNGRPGSFWSTPVDEAAAHLVEVIREVRPQVLVTYDPDGGYGHPDHIQAHRVAMRAADL
                     AADPAHGSGAPHTIAKIYWNRVEREVLEAAFDRLRTTAPDAFPGIAAVADVPGVTDAEQ
                     ITAEIDGSAYAGAKSAAMRAHATQIAVDGPFFALSNDLGQPLLTTECYQLVRGVRGVAG
                     PERESDLFAGVPLAGAPGAGGGAA"
     gene            complement(20471..20665)
                     /locus_tag="IE135_RS07595"
                     /old_locus_tag="GCM10010253_15360"
     CDS             complement(20471..20665)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009190440.1"
                     /locus_tag="IE135_RS07595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_15360"
                     /product="hypothetical protein"
                     /protein_id="WP_010063247.1"
                     /transl_table=11
                     /translation="MALSISAVVLLAIIVFLLIRKSGLKGGHAVVCMLLGFYIASSSIA
                     PTISDLTTNVAGMISSIKF"
     misc_feature    complement(21394..21408)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
     misc_feature    complement(21645..21656)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
ORIGIN
        1 gactcggtgg gcctgttcca gcagcggccc tcgcagggct ggggcaccgt ggagcagatc
       61 atggacccgg tctactcggc cgggaagttc tacgagggcc tggccgaggt gccgggctat
      121 tcgcgcctcc cgctgaccgt ggccgcgcag cgcgtgcagc gcagcgggtt cccgcaggcg
      181 tacgcgaagc acgagccgga cgccgcgctg ctcgcggccg cgctgaccgg gcgcagggcg
      241 gcctcgttga actgcacccc gtcgacggcc acggccgagg gcccggggga tgccgggcgg
      301 gtgcgggccg agttggtgcg ggccttcggc aaggacgtgc tgcccgccgc gaaggccgcg
      361 ggcgcgtccg ccgcctcgac cgtctcggtg cccgtcccgg cgacctcggc gcgggccgag
      421 gacaaggcct cgccgcggcg cggctgggag ctggcgcact gggccgtggc gcagtccgag
      481 gcgctgcgga tcgagcgcgt gagctatgcg gaccgggtct gggacgccgg cacgggctgg
      541 cggacggaac gcgcgaagga caaggaaacg ggcacgaacg cggtcaggat ccaggtcgtt
      601 cagtagtacg ccccgtccct cgttcgggcc atgggggcca catccccaag ctctttccac
      661 caccctcccc gcagtcgcgc agccttgctc cgattccctt gccgcacaag ggaagtgacg
      721 gttcatcggg tctcggcggt atggattgtt tgcccgggtt cttccgctgc ggataatcgg
      781 acccattact cagtctttac cttcgcccac cgcaaccttc ccctcccccg aagcggttgt
      841 cagtgcgtcc gatcaccgga caaggaaatt cgtgcacaac ccgctgaagg agcatcatgt
      901 ccctccccct gacccgtcgg atcgctcgtg ccgcgctgct gatcgccgcc ggcgcgaccc
      961 ccgtggtcgg tgcggccggt gccgcgagcg ccgcagatct cccggcggcc cccgagctgg
     1021 gcggcctgac cgcactggac ggcgcgaacg cgggcgacac cctggacagc gccgcccggc
     1081 agggcaccca ggccgccggt gagaccggtg gccgactcgt cgggaccgcg ctcccggcgg
     1141 cgggcgagac cgtcggcaag tccgccaagg tcgccgtccc ggccgcccag gagaccgccg
     1201 gccaggccgc gggcaacgcg ggccaggcag tcggcggggt ggccgaggcc gccggtggcg
     1261 gtctgcccac cgacggcctc ggcgaggggc tgcccaccga cagcctcggc aagggcggtc
     1321 tgcccaccga cgccctgccg ctgaacggcc tgccgatcgg ctgaccggat cacccacacg
     1381 cgagcgggcc tgaggagtgc gcactcctca ggcccgctcg cgtcgtccgg gccccgcttg
     1441 tccgggtccc cgcgtcgtcc ggggccccgc gtatccaggc cctctctcgc gtccgggtca
     1501 ggacaggcgc ttgaccgccg ccgccacccg ctcgtccgtc gcggtgaacg ccacccggac
     1561 gaagctcgcg cccgccggcc cgtagaagtc gccgggcgcg accaggatgc cccgctccgc
     1621 gaggtacgcc acggtgtccc agcacggctc gtcgcgggtc gcccacaggt agaggctcgc
     1681 ctcgctgtgc tcgacccgga agccgtgcgc ctccagggcc ccgcgcaggg ccaggcgccg
     1741 gtcggcgtac cgggcgcgct gctcggagac gtgcacgtcg tcgccgaggg cggcgacggt
     1801 ggcggcctgg accggggcgg gcgtcatcat cccgccgtgc ttgcggatca gcaacagctc
     1861 accgaggacg gccgcgtcgc ccgcgatgaa cgcggcccgg tatccggcca ggttggagcg
     1921 cttggagagg gagtggaccg ccacgatgcc gtcgtagtgg ccaccgcaga cgtccgggtg
     1981 cagcaccgag accggttcgg cgtcccagcc cagctccagg tagcactcgt cgctgaagac
     2041 gaggacgccg tgctcgcgcg cccaggccac gatccgggtc agctcgtcct tcgacagcac
     2101 cttgccggtg gggttggacg gcgagttgag ccagagcagc ttcagccccg ccgggtccag
     2161 ctcggtcggg tcgtcgtaga cgacgggctc cgcgccgcag agccgggcgc cgacctcgta
     2221 cgtcgggtag gcgagccggg ggtaggccac cttgtcgccc gcgccgagcc cgagctgcgt
     2281 cggcagccag gccaccagtt ccttcgagcc gacgaccggc agcacgttgg cgtggctgac
     2341 gccgaccgcg ccgaggcggc gctccaccca gccggtgagc gcgtcccgca gggcctcggt
     2401 gccccacacc gtcgggtagc cggggctgtc cgcggcggcg accagcgccc gctggatcag
     2461 ttcggggacc gggtcgaccg gggtgccgac cgacaggtcc acgatgccgt ccgggtgggc
     2521 ctgggccgtc gacttgtagg gcgcgagctt gtcccagggg aagacgggga ggcgggagga
     2581 gactgcggac acggagctct gctttctcgg ggggttcgga tacggcggca cggggaaacg
     2641 gctcggtccc gcacgggacg agccgtacgg gaccgggctg cgcgcgtggt gccgccgctt
     2701 actggttctg cggcggcagt ccggcgatga acgcgtggtc gcgctcgatg agaccgagct
     2761 tggaagcacc gcccggcgag ccgaggtcgt cgaagaactc gacgttcgcc ttgtagtagt
     2821 ccttccactc ctccggagtg tcgtcctcgt agaagatggc ctcgaccggg cacaccggct
     2881 cacaggctcc acagtcgacg cactcgtccg ggtggatgta caaggaccgc tggccctcgt
     2941 agatgcagtc gacggggcac tcttcgatgc aggccttgtc cttcacgtcg acacaaggct
     3001 gcgcgatgac gtaggtcacg ctgtcgttcc tcctcggtag ggcgttggct ctcgcgcggg
     3061 agcgcggcgt cgtcgatgcc cgcccctagt atctccgttc tcgggcacga tccgaacagg
     3121 aggggcggac agagctgtgg aattcaccat cggcggacgg ctggaagtcc gcatcacacc
     3181 cgctgacgtg ggcaaacgcg tatccgtgcg gcgtcggacg aacagtggcg gcacgggcgt
     3241 ggagttcacc gacgtggtcg gcgtgctcac atcatggaac gacggtgtga tggcgatcac
     3301 acgaaggggc ggggaatccg tccacatcgt ggaatcttcc ctggtcgcgg gcaaggtcgt
     3361 acccgccgcc ccggcccggc ggcggggccc cgccgcctcc ttcgaggagc tggcggccgt
     3421 caccgcgcgc gcctggcagc cggtggagaa cgaaacgctg ggcgactggc ggctgcgcgc
     3481 ggccgggggt ttcacccggc gcgccaactc cgcacttccg ctcggcgatc cgggtctgcc
     3541 gctcggcgag gcgctcgggc gcgtccgccg ctggtacgag gagcggggtc tgcccgcgta
     3601 cgtccagacg gcgaccgggg ccgagggcac gcaggagttg ttgtgcgccg agctggaggg
     3661 acacggctgg cggcgcgagg tgtcggcgga ggtgcggatc gccgcgctgg ccccggtcgg
     3721 tgaccgggag gcggaggtgt ccgcggtccg gctgacccgg gagccggacg cggcctggct
     3781 cgcccgctac cagcgattct ccacccccgg cccgcatgtg ctgcgggtgc tgggcagcgg
     3841 cccttcggtc tggttcgcca cggtgccggg cagcggcgac gcgccggacg cgatcggccg
     3901 gtgtgtggtg gacggccggt gggcggggtt catggccgtg gaggtcgcgc cggagcagcg
     3961 gcggcgcggg ctggccacgg cggtgatggc cgcgctggcc ggccgggcgc tggacgaggg
     4021 cgcctcggcg gcctggctcc aggtcgagga ggacaatgag ggggcgcggg cgctgtacga
     4081 cggcatgggg ttcgcgggcc atcaccggta ccaccactac cgctcggcgt gagggggcac
     4141 gcggcggact ccgggggccg ggaccggggc cggcgtcgtc acgggggccg gggccagggc
     4201 gggaacagga cgggcaggaa cgtgggtcgg acatgagcgg gctggattcc ggggcggccg
     4261 atcggcggcg gcagttcgcc gaggaggccc ggtccgagcg gcctgacctc gccctcctct
     4321 gcctgctgct gggcgcggag gccggaccgg tcggaccggc cgaggtcgtc ccggtgactc
     4381 cgggggaacc cgtccccgac ccgtacggct tcgatgccgc gcagatcgag ctggaccggc
     4441 tggcggggct gctgccccac ggctcccgct cccccgccga ctgggcctcg gcgctggccg
     4501 aactgctggg tgagcgctgc ggattcggcg gctcctcggc cgactaccag cggctggact
     4561 cctcgctcct ccagcaggtg ctgcgccgcc gccggggcct gccgatcctg ctgtccgtcg
     4621 tctggatcga ggtcgcgagg agggcgggcg caccggtgtg cggggtcgcg ctgcccgggc
     4681 acttcgtggt cggcttcggc gacctggaac acctggttct ggccgatccg ttcgccgggg
     4741 gcgcgccgct gtccgaccgg gacgcggagc tgctggtgag gggggcgacc ggggcgccgc
     4801 tggagccgtc gatgatggtg ccggcccgtc cgctggagat cgtgctgcgg atcctgaaca
     4861 acatccgggc gtgggcagcg gcccggcccg agcgcacgga cgtggccctg tgggcggtgg
     4921 agctgtcgct gctcctgccc tcgcacccgg ccaggctccg ctacgagcac gcccagctcc
     4981 tggtccagcg cggtgagttc ctgcgcgggg cggcggagat ggaggaatat gcggaggtcc
     5041 tcgccgggat cgagccgacg gcggccgaga acatccggcg caaggcccgg gcggcgcgcg
     5101 ccctgctgaa ctgaaccccg ccttccggta aaggcttccg cggatcggcg gttccgtgga
     5161 catgccggtc cgcggaaatc tgcctgacct cactcgtgca agcaccccgg ccgtgacgag
     5221 agggatgggg ccgtgagcga cgtgcgctcc cggtttacat ccgaacgccc ccttccgcgc
     5281 ccaacagccg cgttattcgg ccggttcgtc ggcgtagacg aatgcccgtg cgctcaactg
     5341 gaaacccgtc acggggcgcg cacggcccat cgcattccgc gttgggcggc cggaagagaa
     5401 gagctgaggg cagattgatg acaaccgtgc tgctggtcca caccgtgccg ttgtggcgcg
     5461 cgtcgctggc ctcgctcctc ggcacggggc ggggcataga ggtccgcacc gccgaacgcg
     5521 gtgcgataca ggccgccttg cacggaaccg gccccgatgt gctgctcacc gacctcgact
     5581 gtccgggcgc acgggacgta ctcgccgagg tgaagacggc caccgcaccg cacggaggaa
     5641 cgtatcccct cgccgtgctc acctgtagcg accagccgcg cggcctgcgg cgggcgtacg
     5701 aggcgggggc gctcggctac atcgacaagt accgcccggt ggacgatctc tccgaggtga
     5761 tgcacaagct ggcggacggc ggacggcata tcgacgagtc gctggccttc agtctcctcc
     5821 aggtggccga catgccgtta tcgccgaggg aattgagcgt gctctcgatg gccgaggagg
     5881 gtgacaacgt ggcggggata gccgcgcggc tgcatctgac cccgggaacg gtccgcaatt
     5941 acctggccgc cgccatccgg aagtccgggg cgcggaatcg gctggacgcg atcagacggg
     6001 cgaaggaggc ggggtggatc tgacgatgcc gcgctcgtcg tcccgccgcc gctcgtgccg
     6061 ccgcgctccc cgctcttccg gccgcggtcc ttgcggtcct tccggttccc agaggccgga
     6121 caggtcgcgg tagagggcac tggagcgcag gagttcggcg ggggtgccgc accgggtgcg
     6181 cgggccgtcc atcaccaggg tgcggtcggc gcgacgggcc gagctgagcc ggtgcgcgac
     6241 gacgacgagt gcgcccggca gggcggcgaa cgccagctcg gcgcgggtct cggcggccgg
     6301 gtcgagccgg ctggtggcct cgtcgaggat cagcagcggc ggtgcggcga gataggcgcg
     6361 gccgagggct acgagctgcc gttcgccctg ggagagccgg cccggttcga cggccgcgtc
     6421 gagggagccg agccgggaga gcagcgcgtc caggccgacc gcgtccgcca tggccgcgat
     6481 ctcctggtcc cgggcgtcgg gccggaggta gcggaggttg tcccgcagcg tcccgctgaa
     6541 cacataggcg tgctggggca gcaggacgcg tacggccgtg gcgtcggccg gcctcgccgg
     6601 gcgcccccgc ccccccaccg ctcccccggt gggccgctcg gtcccggcga ggacggcggc
     6661 cagggtcgac ttgccactgc cgctcgggcc gacgaccgcc aggtgctcgc ccgccccgac
     6721 cgtcagcgag agccggtcca gaacggggtg ggcgcggggc ccgtaggcga aggtgaccgc
     6781 gtggagctcg gcgaccgggg cgtcccggtc ggggcgtgga ggaggcgacg ggtcctcgtg
     6841 ggaggtggcc ggggccggtt cctcggcggg cgggggcggg gcgtccgtga aacggtccag
     6901 gaccacgacg aggcggccgc ccgccgtgcc cagcatggtc atcagcgcct ggaccgcagg
     6961 ggcgagcgcc tgggtgaggt aggtcagcgc accgacgaga ccgcccggcg tgagcccgtt
     7021 ccgcaacagc cagggcgcgc ccaggagcag caggagcggg gggaaccggc cgcagaccgc
     7081 gagggccacc acccgtacgg ccgaccagcg ggccagcgaa cgggaggcgg cgagctgcgt
     7141 gtcggcgagg gcccgggact cggccaccgt ccgttcggcg gtcccggcgg cggcgatgtc
     7201 cctcacggag gcggcgagct cgcccgcgtg ggcggcgtac gcctcgtcgg cggcgaggta
     7261 ggcgcgctgg cgggcggcca tcggcggcag ggtgccgagg aacagggctg cccccaggac
     7321 cagcggtggc agcacgatga ggaggagggc gggtgagagg gccagcaggc cggtgacggc
     7381 tccggcggcc gtgaacacga acgaccgcag ggtcaggacg agtccggccc agccgtcccg
     7441 ggcgatctca ctctgatggg tgacctggga gagggaccgg gtgctgacgt cgccggagcc
     7501 gccgagcgcg ccggacagcg cccgcgccac cgcgcgccgc accagcccgt cgcgcagcgg
     7561 ctccaccagg tcggcgagcc ggccgaacac gcctcgggcg gcgagcacgg agggcagcac
     7621 ggcgacggcg gcgacggcca gccagaggag gccggacgcc ggacgtccgg cgaggaagcc
     7681 gtcgtcgagg gcgcgggcga ccccgtatcc gctgaggaag gtctgcgcga actccagcag
     7741 ggaccatccg gccagccgca ggatcgcccc ggtgcgcgcc cgcaggaagg gccgggcctc
     7801 gcgggcgacc cggcgcagag ccgtgtcgcg ggcggggcgc gccggggcgt ggccgggctt
     7861 catcgggtct ccgctgcggc gagaggggaa ggtgcggtgg tgtccgtacc ggtggcggtg
     7921 gtgtccgtac cggtggccgt ggcggcggct gtggcgtccg cgccgctgct tccggcggcc
     7981 gtcgtgccgc ctgtaccgct gctgcccgta ccgctgctgc ccgtgctgaa gaccgcccgg
     8041 tagtccgggt cctgccacag ctcgtcgtgg cggcccgtcg cgcggagccg gccgtcctcc
     8101 agccaggcga cccggtccgc ccgcgcggcc gaggagagcc ggtgggcgac gatgatccgg
     8161 gtgcactgcc ccgcccgcgc gtcgagggcg cggcggacgt ggtgctcggt cacggtgtcg
     8221 aggctcgaca gcgcgtcgtc caggatcagc aaccggcccg gatgggcgaa cgcgcgggcc
     8281 agccccaggc gttggcgttc gccgccggag agcggggcgt cggccaccgg ggtggcgtac
     8341 ccgtacggga gcagcgcgag gaacccgtcg gcgcgggcgg cgcgggccgc ttcgcgtacg
     8401 gcgtcggacg aggcggtcca ggggccgtgg gcgatcgtgt cctcgacggt ggtgccgagg
     8461 agggcgggac gggcgaaggc gtacgccacc tcgcggcgga gccgggccgg ttccatggcg
     8521 tccagcggga cgccgtccag cagcacgctg ccggtgtccg ggtcgagcag ccgcccggcg
     8581 accgcggcga gctgggactt gccggagccg gagcgtccga cgacggccag ggacgtgccg
     8641 ccggggacgg tcaggtggac gccggtcagc agggggtggc cgtcctgtgc cacgccgacg
     8701 tcccggagtt cgaggtgtcc gggggcgtcg aggaccgggc ccaggccgcg gtgcggcagc
     8761 ggggcgaggg tgaggagggg gtcgaggctc cgggcggcgg cgcggctgcg ggccagggag
     8821 ccgagcgctc cggtgagggc gccgatgccg acggcgaggc tcgcgtagcg ggaggcggcg
     8881 acgaggtcgc cgacgccgat cgcgcccgcg gcgagccgga gtccggcgac cgcgaggacc
     8941 agcagcatga gcaggggcag caggagtccg ctgcggccga cggcccgccc gtacacggtc
     9001 caggtccggc ggccgtggtc ggcgagggcg gccaggggct ccaggacgcg gcggtgttcg
     9061 cgggctccgg tgcgggcggc gcggatggtg tcggcgccct ccagggcttc ggtgagccgg
     9121 tgggcgatga gcgactgggc gcgctggtag tcggccccgg cgtcggcggt gtgccgggtg
     9181 aaggtgcgca gcagggcgac gaggagcggg gcgcccagga ggagggcggc ggccgtccag
     9241 acgtcgatga ggaagaggcc gacgagcgcg ccgagcggaa gcaggacgcc cgcgacggct
     9301 ccggcggcgg tgacgggcgc ggacgcggcg tcggcggtgc gggcggtgag ccgggcggtg
     9361 aggtcaccgg tgggcagggc gagggccctg cgcggttcgg cggccaggat ccgggcggcg
     9421 gtgcgggtgc gcagggacgc ggtgagccgg gcggtggtgg tcgtgccggt cacggcggcc
     9481 gccgcgtcga acccggtctc ggcgagggtc agggcggcgc agagcagcaa cccggaccag
     9541 ggcacgggtc cgccggagac gagccggtcg acggtgtggc cgagggcggc gggcagggcg
     9601 agggcggcga gcgccccgcc ggtggagcag aggaacagcc aggtgagggc ggccgggtgg
     9661 agccgggcga gccgccggac gccggacgcc tcgccggggc tcgggtccgg gggcggcagc
     9721 ggcacgggct cgcctttcgg atcggtcggc gggacggccc ctgggggcac gtggccggcc
     9781 ggcccgtcgg tggtgcgcac cgacgggccg gccggggcgg gtcacggggt gcagaggacc
     9841 acgctgaggg agctgtactc acagaccagc agcgagacct ggctgcccgt ggcgagctcg
     9901 ccgaaggagt cctcggccgg ggtgtccatc gcctgaaggt cgagaagggc catgatgtgt
     9961 cctttcgggg acggttgctt actgaacggt ggtgttgcca cgacccctgg aggggccggt
    10021 ccgtggggcc gctgtcgcgg ccggttgcgc cgccggagcg gcgggcagga agggaagtcc
    10081 ggtggggcgg cccgacgcgg cgcccagggc gaggagagcg ccggcggtcc cggtggccag
    10141 gtccatcgac aggcgcatca actgctcgcc ggggaaggcg agtccgccgc cgtacggcag
    10201 ggcgtggctg cccagcaggt cggtgtggcg gtcgaccgcg cgccgccggt ccgccgggtc
    10261 gcacagcggg gtggccgcga ggtgcagcag gagtccggcg gagcccctga gcagtccggg
    10321 ctggacgtag aaggcggaga acgcggccgg gaggagggcc cggcccgccg ctgccagctc
    10381 cgggtcgggg cgctgggcga ggtaggcgtc gatgacggcc gcgatacccg cgctgcccga
    10441 accgacgtac ggcatcagcc gtttgccctc gacgacgagg agcgccccgt cgtccccggc
    10501 ccggcagcgt tccaggtcgc ggcggagtgc ggtggcggcc aggtccagca gggcggtgtc
    10561 cccggtggtc gcgtaccggc ggatcagcag cagggcgata ccgctcgcgc cgtgcagcag
    10621 tccggtgcgg ggcgacggcg ggccgtccac gagcgcgcgg acggcgagtg cggtgcagcc
    10681 ggccgcggcg gtggacaggg ccggggcgtc ggcggcggag gcggtgcggg ccaggtcgtc
    10741 gagggcgagg ccgatgcccg cgtacccgtt gtgcaggccg ggcgcgaggc cctccagggg
    10801 ctggtcgagg atgatgcgga ggaggtcggc ggcctcggcg gtgcggccga tccggtgcag
    10861 ggtccaggcg atgccggtga gcccgtcgta gaagccgagg gggctgccgg acgcggggtc
    10921 cttggcgtgt cgcaggagcc agtcctcggc cggtgcgcac ggcggggcgc cggtctcgtg
    10981 gagggcgtag agcaccccgg ccgccccgta cgcgaaggac tggccgccgg tggcggtggc
    11041 gaactgggcg atgtccccgg ggaagcagcg gtcgtcgcgc tccggtgtgc aggaggcggt
    11101 gatggcccgg gccagcgtgt cccgggcgcg cggccagtcg cggaggccgg cagcaaaagc
    11161 cgtgccgcgg gccgctgccg gagccgtccg ggaggcagcc tcccccgcgt cccgcacgtc
    11221 ccgcaggatc tcctcgaccg ccggacgcag cgcgtcctcc gtcaccggga aggcgcgggc
    11281 gatgtcccgg gcgagcccgg cggccttcgt gcggtcgatg ccgaacagtg tcgtgagcgg
    11341 caggtacagg gcgagccgca gacaggcgag cgcgtagcgg tcgatgtcgg tgccgcgccg
    11401 gtcgggcggg gcgacgaagg ccgggttggc gacgatctgc cggcggcgtt cggcggccgg
    11461 ggaggcggcc tcgaagtcga gcaggacgat ccgcccggcc tcctcgtcga ccatcacgtt
    11521 gctcatgtgc agatcgctga tgacgatgcc ccggtcgtgc accgccgcga cggcccgctc
    11581 gacctgcccg tacaactcct ccgcccacgc ggcgtgttcg gcgagcagtt cggccgaagg
    11641 gtgctgccgg gcgagcggga agcgacgggc gaagacggtg ttgagggtgg tgccggggat
    11701 gtactggagg accaggaagt ggtggtcgcc gacctggaac acgtcccgga cggccgggac
    11761 gcagtccagc ccggccaggt gctccagggc ggtcctctcc cgctccagac gggccaccgc
    11821 gtccgccccg tcggcggcca gacctgcgta cggccgggcc tccttgagga cgacctgttc
    11881 gccggtgcgg gtgtcgcggc cgaggtagac cccgccgccg ttggagaagt gcagcgcctt
    11941 ctcgacggtg tacgggaggt cggcgaggcc tacggcggcc cgggcttcga ggtgcggcgt
    12001 cagaaagccg ggcggggtca cccaggaggg gacgcggaag gcgggtcccc ggtcgtccgg
    12061 gacgagccgg ccccgcgggt cggcgacggc gggcacgggc cggccgtccg gaccggagca
    12121 gaagcgggcg gcgaacgcgc cgtaccgggt gtgcacgggc ccgttcccgc accgcagatc
    12181 gctcaggatg tacgggccgt gctcgccctc caggagctgc atcagggcgg tgcacacctc
    12241 ggggaacgct tcctcggacg gcgggtagac ggtgatgaac ttcccgctgc ccgcccggtc
    12301 cgcgtacttg gcgttccgca gggccagcag ccccgcgttc ggtacgcact tgaaggcgag
    12361 ccggtgctcc agnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn cccgtcgggg
    12421 tggtaggcga gccagtcacc gcgccgggag cgggtccacc cctcgggggc ggagccacgg
    12481 acggcggcgt agtacgcctt ctcctcgtcg acggttccgt cgtccggtcc gggggaacgg
    12541 tggggtgcgt cgtagaagcg gcggtccgcc tggcagtacg cggcgtactc cggattcacg
    12601 cacggccccc tcgctcggtt cattcgcgtc gttcgcggcg agagagaaac tgtcacaacg
    12661 accagcggcg cccctagtca ccgttgtcac gactcgtaca tgcgcgccaa ccatgcggag
    12721 cgcaccacgt actgatgcgt atccgctcgt cgccccgcca ggaaagggca ccggccgggg
    12781 gcgtgcgggg gcgcgcaccg ggcgctttcg cctcccctca gcccgcgccg tgcaccaggg
    12841 cgtcgcccgc ctccgtacgg aaatagagca cggagcggcc cgcccggcgg cggcggacca
    12901 gcccggcgtc caacaggatc cgcagatggc ggccgaccga acccagcccc tggccggtca
    12961 gcgcgacgag ctgcgtcgtg ctgagcgggg aggccagcag caacaggacg gctgcccgcg
    13021 cggggccgat cagcgcgccc agggcggtgg gtgcggaaac gcggcccgcc tcggcgagca
    13081 ccccggaaca cgggtacacc agcccgtacc ggtgcgggat gtcccagcag acccaggact
    13141 ggtccggggt gacggggatg aacaggagct gggcgcggtc cagttcgcgg ggcgggttgt
    13201 cgtaggtgtt gatctgcaac cggctgccgc ccagccaacg gatgccgggc cgcatgccgt
    13261 tcagggcccc ggcccagccg gcccgtccca actgggcggt acgggcgatc acgtcggcct
    13321 ccaggatccg ccgccgcctc ggccagtcgg gcagcacggt gtgcgtccag acccactcca
    13381 gggcgtcggc ggcacgctcg gccaggtcgt cccggtccag cgcggcgggc agcggcccgc
    13441 ccagcgcctc ctccagatcg gcccgcgccc ggtcgggcgg ggtggcccgg acccgcgcca
    13501 gctcctcggc gaaggagggc ggggtctggc ccggcggtac gggtaccggg gcgggggtga
    13561 ggaagtcggc ggtccagcgg ggcgcgaggg cggagcggat cacgagggcg gagaccgggt
    13621 cgtcggccgc ccgtcgccgg tacgcgggca gatgggcctc cagccaggca cgctcccccg
    13681 ggtgcgcggc ggtggcccgc tccaggagca gcaggctcgc gacggcctcc gcgagcggcg
    13741 agacgacgaa ccggctgccg gcgagcgtgt ccgcactgac ctgccaccag cccacgccca
    13801 ccaccgcccg ttctccgtca gccctgcggg ccgcgcccga ccgtctcaat caggccgccc
    13861 cgtgggccgt gcccgaccct gtcgacgagg ccgccctgtc ggccccgtcc gtcgggccgc
    13921 gcggtcggcc cggccgcccc ggttcaggag accccgcacg ctccgccccg gctttcgcgt
    13981 ccgcgcgaaa cagtaaccgc ccccgtgacg gcgtcccgag actcccccca tgcgcaccta
    14041 ccgcgaactg ttccggaccc cggagttcac ccccttcttc gcggccgtct ccgtgcagac
    14101 ggccgcccag accgcgaccg gcctcgccct cggcaccctc gtgtacgcgc ggacgggctc
    14161 gcccctgctg tcggcgctgg cgatgttcgg cccctcgctg gcccaggtgg ccggggcgct
    14221 gaccctgctg tcggcggcgg accggctgcc gccgcgcgcc gcgctgaccg ccctcgccct
    14281 gctgtcggcg ggggccgcct gcgtccaggc cctccccggg ctgccgttgg gggtcgcgtt
    14341 cgccgttctg ctcgtggtgg gcgtggccgc gtcgccgggt ggtggcgtgc ggtacgggct
    14401 gctcaacgag atcgtgccgc gtgaggggtt cctgctcggc cgctcggtgc tgaacatggc
    14461 gggcggcgcg atgcagatct gcggattcgc ggtgggcggg gcgctggtgg cggggttctc
    14521 ggcgcgcggc acgctgctga tcggggcggc tctctacgtc gtcgcggcgg ccgtgacccg
    14581 gttcgggctg accgcccggc ctcccagggc gaccggccgc ccctcggtcc gcgagacctg
    14641 gcggacgaac gcgctgctct ggtcgtccac gccgcgccgg tacgtcttcc tcgccctctg
    14701 ggtccccaac ggtctcgtcg tcggctgcga gtccctgtac gtggcgtacg cgcccgggca
    14761 cgccgggctc ctcttcgccg gcggggccct ggggatgctg gccggggaca cgctggtcgg
    14821 acggttcgtc acgacccggt ggcgggcgcg gctgggggct ccgctgcgac tgctgctcgc
    14881 cgcgccctac ctcctcttcg cggtgcgccc ggggctgccc ctcgccctgg cgctggtcgt
    14941 cgtggcgagt gtgggcttcg ccgcgagcct gctgctccag gaacggctgc tggccctcac
    15001 cccgcccgag ctgagcggcc aggcgctcgg gctcagctcc tcggggatgc tcgcgatgca
    15061 gggggcgggt gcggccgtgg cgggcggtat cgcccagctg acctcccccg cgacgggcat
    15121 ggcggcggtc gcgggcctct ccgtggtggt gacactggcg ctggcgccgg ggctgcgtac
    15181 ctcgccgggc gccgacgggg gcagactgct cggagcggac ggatcaccgc gtgcttcccg
    15241 tacgccccgc accacacacc ccgcaccgga agagacgaca tgagcgacga gaccaggcgc
    15301 agccagaagg aagccatgct cgcgggcgag ccgtacctcg ccgacgaccc cgaactggcg
    15361 gcggaggccc tgcacgcggc cgtgctgagc gagcgctaca acgccacgtc ggccgccgac
    15421 cccgaggccc ggcgcgcggt gctggccgag ctgctcggca aggtgggcga gggcgtggag
    15481 gtacggccgc cgctgcgggt cgactacggc taccggacca ccatcggccc gcgtacgttc
    15541 atcaacttcg gcgcggtcct cctggacgtc gcccgcatca cgatcggcgc ggacgtccag
    15601 atgggcccga acgtccagct gctcaccccg acccacccca tcgaccccga gcagcgccgc
    15661 gccaagtggg aggccgccga gccgatcacc atcggcgaca acgtgtggct gggtggcggg
    15721 gtcgtcgtct gccccggggt caccatcggg gagaacacgg tggtcggcgc gggggcggtc
    15781 gtcacgaggg acctgcccgc gaacgtggtg gcggtcggca atccggcccg ggtgatccgg
    15841 acgatcggcg agccggaggc gtaaccagcc gtctccacgc acccgggcgc tccccgcacc
    15901 cccgcgctac gccgcccgcc aggcgtccgt gacgcacgag acctcgaagt gccaccagcc
    15961 ctcgtcccgc ccccgggtga gcagcgcctt cactccgcgc agatccgcgc cgcccggcac
    16021 ggtcagggcg accagcggaa agtcggcgct gaagacctcg cccgtgagcc cgaacccggc
    16081 gagccgctcg tgcacggccc gtacgtcgcg cccgagcgga ccgtccggca cgggcagcac
    16141 gcgtacggtg cagttgcccg agtccgccac ccgctcgccg gcccagtgca ccccgtcgcc
    16201 gtccgtccgg aaccgtacgg tctccccctc ggcgagaccg tcgcgcagga agggcgcgtt
    16261 gtccacccgc gcggtgtccg ggccgagccg ggtcgcccac aacccctcgg tctcgtacgg
    16321 cagcggcccg tcctcgcgcg ggggcagccg gaaccagacc ttgatctgat cggcttcgcg
    16381 ggacgggcgc tccgggcagg cgggggaact catggcccca tggtcccgcg cacgcggcgc
    16441 gtccgcctgt ccacgaccac cgcctccgcc tccgcctccg cctccgccac gacgggcacg
    16501 gcatcagctg gtgaagccgg cggccgcccc cggcgcgccc ggaccgcgca cttnnnnnnn
    16561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnggtca
    16621 ggttgatggt gaccgtgcgc tcggccgggg tcttcccggt cagggcggtc ttcatcgcct
    16681 gggccacgtc gtccgggccg acctggtgct tctttccgtc ggccttgacg gccatgatgc
    16741 cgtcgaagac gccgtcgagc agcgtctcga tcgccttctt gtcgtagacg tcgaccagtc
    16801 ggccgtccac cggcttcatg gacaggatct gcggcagcga ccgggccggg ccgaactgga
    16861 tctgcttggg accggccttg atggtgatca ggtcggacat cgcgggctcg gcgaactcct
    16921 tcatcgcccg gttcagttcg gcctgggtga tggtgggttc gctggtggtg acggggagtt
    16981 cgaccacctt ggcctgcccg gtctggacct gggcgcggta ggcgtcccgg accgagatca
    17041 gggactggcc ggcgtccagc gtcttgcccg gcttgcccgg caccgcaacg gccttgttcg
    17101 gctcgaagcg gatcgtgccg tcgttggccg aaccggaagc gcccgccagg tcggtcagcg
    17161 ccacgccgag cttctcctcg tcgaccggga tcaccgggtc ggcggggcgc tctccgccga
    17221 acagcgaacc gatcaccgag acggggttgt agtcgctgcc cgccgcgccg cgcacggtct
    17281 cctggctgtc cagggtgaga ccggccttct cggggtcgag cttctcctcc ttgccgtcca
    17341 ccgacagcgt gagaggcgtc ttggcccgct caccgagggc ggcttcgagc ttggtgaccg
    17401 cctcttcctt cgtgccgccg ccgatgtcga cgccgagcac cgtggtgccc ttggggacct
    17461 cggcgtggtt cagcaggaga cccgccccgt acgcgatgcc gagcagcacg accgcggcca
    17521 cgccgagcag gaccagcttg gagcggccct tcttcgcggg ggcggcgggg gcggacgcgg
    17581 tctgcgacgc ggggcgcggg gcggtgggcc ccggcgtggg aacacccggt ccgccggggc
    17641 ctccgtggcc cgtcaccggg gcgccggggg tgcccggccc gcccgggaac ggggtgcgcg
    17701 gctcgctggg caccacgggg atgccgctgg tgagcgtgtc gcccgagaca tggccgccgg
    17761 ggccgggctc gggcgccggg gcctgcgggg tgaggatcgc ggtgtcgtcg gacatccggg
    17821 gcggtacgcc gccgggggtg cccgggacca tcgggccggg gccgccgagg cccgggacac
    17881 cgtcgaggtt cggggtcagc gaggaggcgc cggtggccgg tcccgtggtg gggccggacg
    17941 gaccgggcgt acgcatgccg ggaccggggg tggcgcgcgg gcctccgccg ggaggctcgg
    18001 tgccgtagct gtcgagcgca ctgcggccgg ggccggagcc gggcgcgccc ggtccaccgc
    18061 cggacttcgg cgcgtccgag aagtacggca ggtcggggcg cgaaggtccc gcgcccccgt
    18121 cggacgcacc accgggacca ccgggaccgc cgggaccgcc ggagccggga ccgcctgcac
    18181 ccggaccacg cgccccaccg ggaccgctct ggccgcccgg accacccgcg ccgccgggac
    18241 caccgggcgc acccggaccg ccctggccgg ccgtcgccgg gcctgcggtc ggggccttgc
    18301 gcggagcgaa ccagtcgctg ccgctcttct cccgggccgg cttctccgcg ggcgtcgggt
    18361 cggcggccgg gccgccgtcc cgggaccggt ccgcgggggc gccgccgttc gagccggagc
    18421 ccgggccgcc ggagcggtcc gagggtccgg tgccggcacc ggcgctcgca ccggtgcccg
    18481 gtgcggccgg cggcgtgccg ggccgcgggg tcgcgcccgt gcgctcggcg tcggaacggc
    18541 cgccgccgga gatgtcgctc tccgccatcg gcgtacgcat gacgaccggc gggatgggac
    18601 gcgagccggg gatgttgatc cggatgcgcg tcgtcagcgt cgtctcggtc ttgggttcct
    18661 cgggccgggg cggatccacg gattccgggt tctcgtcaga gccgtcctgc gacgggtgga
    18721 gcgacggata ctggcgggat ccgtacggcg gcgtacccga ggggtacgcg gctccgccgc
    18781 ggccctgggg cccggaggac gaactgtcag tttcacgact caaagcaggt tctcccgatt
    18841 ggctccgccg cccgtacttc ccccatgccg caggccaggg gacggctcgg cgcgcgcacc
    18901 accatactgg ccgccgccgt cggacactcc gcggccgggg gaaacctcca cccgtgcctc
    18961 acacctgtga gggtcgccga cggcccggac gtggcacttc atgtaccgga ccggccgctg
    19021 tggatggctg attgcggcac cttggaggtg gtggcacaga tcacagcgac cgccgtgccg
    19081 ccgagcatga agagcaccag gccgagttcg tcgccgaaga cgtagtcgcc ctccggccgg
    19141 ccgctcagca gcaggaagac ggtgatgaac cagccccccg ccggggcgag cgcgccgatc
    19201 tgggtgcggg tcaggatgcg gccgccgtag aagagtccgg cggagccgag cagggcgatg
    19261 atcaacccac cggggaacca ggccgcttgg acgagggttc cggcgagggc gacgagcgcg
    19321 ccgaggaccg cgaggcccaa gtgggcggcg atccgggccg ggttcggccg ggcggcgaaa
    19381 ccgatgggcg cgggctccct ggggggtgcg ttccggcgcg gcgcgtggga ggagtccgcg
    19441 cggccgcggg ccttcttggg ggcgtcgctc atgccgcgcc tcccccggcg cccggggcgc
    19501 ccgcgagcgg gacaccggcg aacaggtcgc tctcgcgctc cggtccggcc actccgcgaa
    19561 cgccgcgcac cagttggtag cactcggtcg tcagcagggg ctggccgaga tcgttggaga
    19621 gggcgaagaa ggggccgtcc accgcgatct gggtggcgtg ggcgcgcatc gccgccgact
    19681 tcgccccggc gtacgccgat ccgtcgatct ccgcggtgat ctgctccgcg tcggtcacgc
    19741 ccgggacgtc ggccacggcg gcgatgccgg ggaaggcgtc gggcgcggtg gtgcgcagcc
    19801 ggtcgaaggc ggcctccagc acctcgcgct ccacccggtt ccagtagatc ttggcgatgg
    19861 tgtgcggggc gccggagccg tgcgccgggt cggcggccag atcggcggcg cgcatcgcga
    19921 cgcggtgggc ctggatgtgg tcggggtggc cgtagccgcc gtccgggtcg taggtgacca
    19981 ggacctgggg gcggacctcg cggatcacct cgacgaggtg ggcggccgcc tcgtccaccg
    20041 gggtggacca gaaggagccg gggcggccgt tctgttcggc gcccatcatc ccggagtccc
    20101 ggtagcggcc cgcgccgccg aggaagcggt ggtcggtgat gccgagctcc cgcatcgccg
    20161 cggccagctc gccgatccgg tgggcgccca gcgcgtcgtc ccggtccgcg gtgaggcggg
    20221 cgagcgaggg cgggatgacc tcgccctcct cgccgagcgt gcacgtcacc agggtgacgt
    20281 gggcaccctc ggccgcatac ctggccatgg tggcgccgtt gttgatcgac tcgtcgtcgg
    20341 ggtgcgcgtg cacgagcagc agacggcggg cggggaggtc cttcatgggg accaccctac
    20401 gagcccggag gccccccgcg cccccgcgcc cctgcccccg ccggtcgccg gtcgccggcg
    20461 cccgcccggg tcagaacttg atgctgctga tcattcccgc cacgttggtc gtcagatcgg
    20521 agatggtcgg cgcgatggac gagctcgcga tgtagaaccc gagcagcatg cagaccaccg
    20581 cgtgccctcc cttcagtccg gatttccgga tcagcaggaa gacgatgatc gccagcagca
    20641 ctaccgccga aatcgagagc gccacggcgg ttcacctcca tcggtacgtt cggacggtcg
    20701 gaacgggggt acacggtgtc agcaggttgt cagcgggttc ctacccaccg agcgctacgg
    20761 atcataactt tccgtgccaa cgcattgatc ggggcacagc agcacgaggg gcgcacgaac
    20821 cgtgccacgc ggccgagttc ggcactaggt tcagagccat gacctcgcag aagctgtctt
    20881 ttccccgtca gcacgcccgg acccagcgct tcactctcgg cgcacctcgc gccttcaccg
    20941 tctcaccgga tgagacacgt gtgatcttcc tgcggtccac gtccggaacg gaccggacca
    21001 cccggctctg ggtgctcgac ccggcgaccg gcgaggagcg gatcgcggcc gaccccgatg
    21061 tgctgctggg gggttcggcg gagaagctgt cggcgcagga gcgggcccgg cgggagcgga
    21121 cccgggaggg ttcggcgggg atcgtctcct acgcggtgga cgcggcggcg gagttggccg
    21181 cgttcgcgct gtccggaaag gtgtacgtgg ccgagctgcg ggccgggacc gcgcgggcgc
    21241 tgccggtgcc gggtccggtg atcgaccccc gcccgtcccc cgacggccgg cacatcgcgt
    21301 acgtggccaa gggcgcgctg cgggtggtgg acgcgacggg cgagggcgac cgggcgctgg
    21361 ccgagccgga ggacccccag gtcacctatg gtctggccga gttcatcgcg gccgaggaga
    21421 tgcaccgcta ccggggtttc tggtggtcgc ccgagtcgga ccggctgctg gtcgcgcggg
    21481 ccgacgagag ccccgtacag cggtggtaca tcgccgatcc ggcacacccc gagcgcaagc
    21541 cggccgaggt cgcctacccg gcggccggga cgcccgacgc ggaggtgcgg ctcttcgtca
    21601 tggacctgga gggggaccgc accgaagtgg tctgggaccg ggaggcgttc ccgtacctgg
    21661 cccaggtgca ctggtcgtcc gcgggtgccc cgctgctgct ggtgcaggcc cgtgaccagc
    21721 gcagtcagcg gtatctggcg gtggacccgg agaccggcgc gacccggctc gtccatgtcg
    21781 acgaggaccc ggtctggctg gatcttttcc ccggggtgcc cgcgtgggcg ccggacgggc
    21841 ggttggtgcg gatcgccgac gagggcggcg cgcgggtgct ggcggtcggg gaccggccgc
    21901 tcaccgggtc gcaactgcac gtccaggcgg tgctggacat cggggagtcg gacatcctga
    21961 tctcggcggt ggccggtgag gacgcggtgg agccggagat cggccagatc catgtgtacc
    22021 gggtcaacga gctgggaatc gagcggattt ccgaaggggt gggtgtgcac tccgcggtcc
    22081 gctcgggtgc tctgtcggtg gtggtctcgg ccgttcccga ggagcccggc accgccgcgt
    22141 gggtcgtgcg ggacggcaag cggctgttcc gtgtcgcgag cttcgcccag gagccggtgc
    22201 tcaccgcccg cgtgaccctg accgaggggg gcgcacggcg gattccgtgc gccgtgctgc
    22261 ttccgtcgga ctaccaggag tcggacggtc cgcttccggt gctgctggat ccgtacggcg
    22321 gcccgcacgg ccgccgggtg gtcgccgccc acaacccgca cctgacgtca ca
//
