LOCUS       NZ_BMSZ01000002        26387 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces badius strain JCM 4350 sequence02, whole genome shotgun
            sequence.
ACCESSION   NZ_BMSZ01000002
VERSION     NZ_BMSZ01000002.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces badius
  ORGANISM  Streptomyces badius
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 555338)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: BGI assembly pipeline
            Genome Coverage                   :: 154X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014649415.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 03:57:07
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,894
            CDSs (total)                      :: 6,825
            Genes (coding)                    :: 6,582
            CDSs (with protein)               :: 6,582
            Genes (RNA)                       :: 69
            rRNAs                             :: 2 (23S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 244
            CDSs (without protein)            :: 243
            Pseudo Genes (ambiguous residues) :: 0 of 244
            Pseudo Genes (frameshifted)       :: 70 of 244
            Pseudo Genes (incomplete)         :: 206 of 244
            Pseudo Genes (internal stop)      :: 7 of 244
            Pseudo Genes (multiple problems)  :: 38 of 244
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:11:55
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 258000
            Orig. end                         :: >284387
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMSZ01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..>26387
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..>26387
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..>26387
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:>16387](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..>16387)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            328..1713
                     /locus_tag="IE135_RS04945"
                     /old_locus_tag="GCM10010253_10010"
     CDS             328..1713
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010058004.1"
                     /locus_tag="IE135_RS04945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_10010"
                     /product="STM4012 family radical SAM protein"
                     /protein_id="WP_069741197.1"
                     /sec_met_domain="PF04055 (E-value: 1.3e-17, bitscore: 59.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTITTSTTAPPAVRPYESYVYAYPHKTAYRPLADRPALRSLWAAE
                     PKDALSLYLHIPFCEVRCGFCNLFTRIGAPEMLTTRYLDALDRQALAVREALGDEEPVR
                     FAAAAFGGGTPTFLTAGELERLCDIAEKRMGADLSAVPLSVETSPSTATPDRLAVLADR
                     GTTRISIGVQSFVDEEARAAVRPQRRADVEAALGRIRDARIPVLNIDLIYGIDGQTERS
                     WLASLDAALAWRPEELYLYPLYVRPLTGLHRIGPAATGPEAQAPEDAAWDEQRLRLYAV
                     GRDHLLAHGYEQVSMRMFRRTDAPREQEGPEDYACQTDGMIGLGCGARSYTSALHYSFD
                     YAVDMREIRSIIDRFTATEDFSRAEVGRYVDAAEARRRHLLQSLLQAAGLPVAEYRARF
                     GTDPGEDFPAELAEFADRGWLDAAAPDGLLRLSPSGLAHSDALGPALFSPGVRAAMAAY
                     ERK"
     gene            1721..2638
                     /locus_tag="IE135_RS04950"
                     /old_locus_tag="GCM10010253_10020"
     CDS             1721..2638
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378201.1"
                     /locus_tag="IE135_RS04950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_10020"
                     /product="STM4011 family radical SAM protein"
                     /protein_id="WP_199887577.1"
                     /transl_table=11
                     /translation="MDLTILYRGPLASCDYDCPYCPFAKRRDSRAQLTADREALERFTG
                     WAAAQTADRLSVLFTPWGEGLVRSWYRRALTELSRLPHIGRVAIQTNLSGRTEWLADAD
                     PERIALWCTYHPGQTPYDRFLGKCRELSAKGIRYSVGVVGFDEHLDEARRLRAELPGEV
                     YLWVNAAEGQTYTDEEAARWTELDPLFPYSRDPHRSAGLPCRTGESVISVNGDGTVRRC
                     HFVEAELGNLYDGSYRRALGPRACPLAECDCHIGYVHLESLPLYDVFAGGVLERIPAAS
                     GTGTPPGGFVVPNTPRRALPLLEP"
     gene            complement(2650..3489)
                     /locus_tag="IE135_RS04955"
                     /old_locus_tag="GCM10010253_10030"
     CDS             complement(2650..3489)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007449852.1"
                     /locus_tag="IE135_RS04955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_10030"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_069740051.1"
                     /transl_table=11
                     /translation="MADDSRNNQQHTIGSYAAIGDSFTEGVGDPGPDGTFVGWADRFAV
                     LLADRLPAPGRAGSEDAPHEDSPHGDFRYANLAVRGRLLDQIVEEQVPRAKELAPDLVS
                     FCAGGNDIIRPGTDPDDLAERFERAVAELSNAVGTVMVTTGFDTRGVPVLRHMRGKIAT
                     YNVHLRAIADRYQCPVLDLWSLRSVQDRRAWDADRLHLSPEGHTRVALRAAQVLGHDVP
                     ADPDQPWPPQAQRSPFDERRDNIQWAREYLVPWIGRRLRGESSGDHVEAKRPDLLPL"
     misc_feature    complement(3557..3572)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.38"
                     /tool="antismash"
     gene            complement(3654..4613)
                     /locus_tag="IE135_RS04960"
                     /old_locus_tag="GCM10010253_10040"
     CDS             complement(3654..4613)
                     /EC_number="3.4.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128943.1"
                     /locus_tag="IE135_RS04960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_10040"
                     /product="LysM peptidoglycan-binding domain-containing M23
                     family metallopeptidase"
                     /protein_id="WP_199887578.1"
                     /transl_table=11
                     /translation="MPAKGKHRRPKSGPISRGVLAAGTGGAALALPLIGATAANAADQA
                     APAAKPAAASVAAAHTAPAAAPAASKAAPKTYSVVSGDYLSKIAAEHRLKGGWEKLYQD
                     NRSTVGDNPSLIHPGMKLTLGAKGSAPAEKSAALKAAPKKAEPAPKAAPKEEAPKGDTI
                     SADDSEGSGAPARTGAAEATGSGWSAPLANANVTTQYRASGASWSSGYHTGSDFQAATG
                     TPVLAIGPGTVVSAGNSGAYGNEVVIQHEDGMYSQYAHQSALNVSVGQTVTGGQQIGLS
                     GSTGNSTGPHLHFEVRTGPSYGSDVDPIAYLRQHGVSL"
     regulatory      complement(4617..4777)
                     /bound_moiety="cyclic di-AMP"
                     /db_xref="RFAM:RF00379"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00379"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-AMP (ydaO/yuaA leader) riboswitch senses
                     the signaling molecule cyclic di-AMP; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(4922..4937)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.65"
                     /tool="antismash"
     misc_feature    complement(5033..5047)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.37"
                     /tool="antismash"
     misc_feature    complement(5131..5146)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.49"
                     /tool="antismash"
     gene            5222..>6020
                     /locus_tag="IE135_RS04965"
                     /old_locus_tag="GCM10010253_10050"
     CDS             5222..>6020
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964842.1"
                     /locus_tag="IE135_RS04965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_10050"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_199887579.1"
                     /transl_table=11
                     /translation="MTQQVPQIPPTEVVLTGVRNFRDVGGLPTADGRRTAFGRLYRSGH
                     LAHATAEDAAFLGGLGLHTIFDFRHSADHRLDGYDIELAGVRNVSIPLSDPADGAEFWR
                     LVGSGNIEQLRSVLSGSKGVDRMIRMYRATIEDRTAEHSRVLHALAEDSVPALMHCAAG
                     KDRAGLSIAVALLAVGVVPEAIEEDYLKSNDLHRRYKVKRSDPSGAGMSPEVLELLDPL
                     FGARPAYLAAAFAAIEENWGTTDRYLSEGLKLSPATRERLRERL"
     assembly_gap    6021..6057
                     /estimated_length=37
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<6058..6195)
                     /locus_tag="IE135_RS04970"
     CDS             complement(<6058..6195)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955417.1"
                     /locus_tag="IE135_RS04970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6126 family protein"
                     /protein_id="WP_199887580.1"
                     /transl_table=11
                     /translation="MSDSEHYDPLGPGRRANEDPQEKRMPRGVIIRLFAYLVAGHIIAA
                     F"
     gene            complement(6260..6868)
                     /locus_tag="IE135_RS04975"
                     /old_locus_tag="GCM10010253_10060"
     CDS             complement(6260..6868)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955416.1"
                     /locus_tag="IE135_RS04975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_10060"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_199887581.1"
                     /transl_table=11
                     /translation="MNPPDEGAPDELPGVAPRLRDLRRARGFTLETAAQRAGLSPAHLS
                     RLETGRRQPSLPMLLGLARIYGTTVSELLGEQPPERDAIIRGGGFEGAEADGWMYRRAG
                     GSGRAMQALRVRVPYGAQGDLVRVHPGEEWLYVLEGRLRVGLGDTVHDLEPGDSAHFDS
                     LTPHRIVAVDRRGAELLFVHSLLQSPAAELCLGSGLHSR"
     gene            complement(6932..8329)
                     /locus_tag="IE135_RS04980"
                     /old_locus_tag="GCM10010253_10070"
     CDS             complement(6932..8329)
                     /NRPS_PKS="Domain: Aminotran_3 (45-367). E-value: 2.1e-91.
                     Score: 298.4. Matches aSDomain:
                     nrpspksdomains_IE135_RS04980_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018492039.1"
                     /locus_tag="IE135_RS04980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_10070"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_199887582.1"
                     /sec_met_domain="Aminotran_3 (E-value: 2.1e-91, bitscore:
                     301.5, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDGGPGGFDLGRLLAERGAERYELHARHLNHQLPRMLHTIGFDK
                     VYERAQGAYFWDAEGNDYLDMLAGFGVMGIGRHHPVVAKALHDVLDAQLADLTRFDCQP
                     LPGLLAEKLLTHSPHLDRVFFGNSGTEAVETALKFARYATGKSRVLYCDHAFHGLTTGS
                     LSVNGESGFRDGFAPLLPDTAVPLGDLDALRRELKRGDVAALIVEPIQGKGVHPAPPGY
                     LREAQELLHRHKALLIADEVQTGLGRTGDFYAYQHEEGVEPDLVCVAKALSGGYVPVGA
                     TLGKDWIFRKVYSSMDRVLVHSASFGSNAQAMAAGLAVLTVMEDEETVANARRTGDLLR
                     ERLAALVDRYELLHEVRGRGLMIGIEFGRPSSLKLRSRWTMLQAARKGLFAQMIVVPLL
                     QKHRILTQVSGDHLEVIKLIPPLVIGDEEVDRFVAAFTSVMEEAHSGGGLMWDFGRTLV
                     KQAVANR"
     aSDomain        complement(7229..8194)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE135_RS04980_Aminotran_3.1"
                     /evalue="2.10E-91"
                     /label="IE135_RS04980_Aminotran_3.1"
                     /locus_tag="IE135_RS04980"
                     /protein_end="367"
                     /protein_start="45"
                     /score="298.4"
                     /tool="antismash"
                     /translation="VYERAQGAYFWDAEGNDYLDMLAGFGVMGIGRHHPVVAKALHDVL
                     DAQLADLTRFDCQPLPGLLAEKLLTHSPHLDRVFFGNSGTEAVETALKFARYATGKSRV
                     LYCDHAFHGLTTGSLSVNGESGFRDGFAPLLPDTAVPLGDLDALRRELKRGDVAALIVE
                     PIQGKGVHPAPPGYLREAQELLHRHKALLIADEVQTGLGRTGDFYAYQHEEGVEPDLVC
                     VAKALSGGYVPVGATLGKDWIFRKVYSSMDRVLVHSASFGSNAQAMAAGLAVLTVMEDE
                     ETVANARRTGDLLRERLAALVDRYELLHEVRGRGLMIGIEF"
     gene            complement(8326..9345)
                     /gene="hpnH"
                     /locus_tag="IE135_RS04985"
                     /old_locus_tag="GCM10010253_10080"
     CDS             complement(8326..9345)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128938.1"
                     /locus_tag="IE135_RS04985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_10080"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_006128938.1"
                     /sec_met_domain="PF04055 (E-value: 2.3e-17, bitscore: 58.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 2e-09, bitscore: 32.2,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQTIKVATYLFEQKLRKREKFPLIVELEPLFACNLACEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIDEIVRQLVARKKYVF
                     LCTNAMLMRKKLDKFTPSPYFAFAVHIDGLRERHDESVAKEGVFDEAVAAMKEAKARGF
                     RVTTNSTFFNTDTPQTIIEVLNYLNDDLKVDEMMISPAYAYEKAPDQEHFLGVEQTREL
                     FKKAFAGGNRARWRLNHSPLFLDFLEGKADFPCTAWAIPNYSLFGWQRPCYLMSDGYVP
                     TYRQLIEETDWEKYGRGKDPRCANCMAHCGYEPTAVLATMGSLKESLRAARESVGGNR"
     gene            complement(9351..10001)
                     /locus_tag="IE135_RS04990"
                     /old_locus_tag="GCM10010253_10090"
     CDS             complement(9351..10001)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964847.1"
                     /locus_tag="IE135_RS04990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_10090"
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_069740056.1"
                     /transl_table=11
                     /translation="MGDPRGSGSPVTPLLVACALGIEQVALRSGRGAPGPVRILRTGMG
                     PRAAEAAVARLLGGPDGLSDAAVIASGFCAGLAPGMHPGDLVVAEETRDADGTTPCTGT
                     GVLVAALTRALPGRRVHTGPLTGSDHVVRGPERAALRAGGAIAVDMESAATLRTALCHG
                     PRPVAAVRVVVDAPEHELVRIGTVRGGISAFRVLRAVLPAFYEWHRSLLLPRR"
     misc_feature    complement(9369..9371)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10001..11998)
                     /gene="shc"
                     /locus_tag="IE135_RS04995"
                     /old_locus_tag="GCM10010253_10100"
     CDS             complement(10001..11998)
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0016866 - intramolecular transferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128936.1"
                     /locus_tag="IE135_RS04995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_10100"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_069740057.1"
                     /sec_met_domain="T2TS (E-value: 3e-146, bitscore: 483.0,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSTGAANTTGAPDDPTDTRTAANDVTDIARRAAERSVEH
                     LLGRQDEQGWWKGDLATNVTMDAEDLLLRQFLGIQDPGTTRAAALFIRGEQLGDGTWNT
                     FYGGPGDLSATIEAYVALRLAGDRPDEPHMARASGWIRDQGGIAAARVFTRIWLALFGW
                     WKWDDLPELPPELMFLPKRVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHT
                     DPDHPNPARKLAPPTSWDGLFQRLDKGLHLYHKIAPRPLRRIAMNVAARWIIERQENDG
                     CWGGIQPPAVYSIIALHLLGYDLDHPVMKAGLASLDRFAVHREDGARMIEACQSPVWDT
                     CLATIALADAGLRPDHPALVKAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYP
                     DIDDTAEVVLALRRVRHPDPARLEAAIARGVRWNLGMQSRNGAWGAFDADNTSPFPNRL
                     PFCDFGEVIDPPSADVTGHVVEMLAVEGLANHPRTREGIEWLLAEQEACGAWFGRWGVN
                     YVYGTGSVVPALITAGLPAGHPAIRRAVDWLESVQNDDGGWGEDLRSYQEEKWIGHGES
                     TASQTAWALLALLAAGRRDTASVTRGIIWLTEAQQADGSWDEPYFTGTGFPWDFSINYH
                     LYRQVFPLTALGRYVYGDPFADRADAAEGM"
     misc_feature    complement(12082..12098)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.23"
                     /tool="antismash"
     gene            complement(12106..13209)
                     /locus_tag="IE135_RS05000"
                     /old_locus_tag="GCM10010253_10110"
     CDS             complement(12106..13209)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964849.1"
                     /locus_tag="IE135_RS05000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_10110"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_069741203.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.9e-61, bitscore:
                     201.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSTTGTRGESVTPANPAFDTVADTADVTALLERGRALSAPVLRA
                     AVDRLAPPMDTVAAYHFGWIDAEGRPSDGDGGKAVRPALALLSAEAAGAPAEAGIPGAV
                     AVELVHNFSLLHDDLMDGDEQRRHRDTVWKVHGPAQAILVGDALFALAYDLLLELGTVQ
                     AGRAARRLTTATRKLIDGQAQDISYEHRERVTVEECLEMEGNKTGALLACAVSIGAVLG
                     GADDRTADTLEAYGYHLGLAFQAVDDLLGIWGDPESTGKQTWSDLRQRKKSLPVVAALA
                     AGGEASERLGELLAADAKSNDFDSFSEEEFAARAALIEEAGGREWTAQEARRQHAVAIE
                     ALHAVDMPHRVRKQLTELADFVVVRKR"
     gene            complement(13206..14591)
                     /gene="hpnE"
                     /locus_tag="IE135_RS05005"
                     /old_locus_tag="GCM10010253_10120"
     CDS             complement(13206..14591)
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010072793.1"
                     /locus_tag="IE135_RS05005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_10120"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_199887583.1"
                     /transl_table=11
                     /translation="MSDESPRPVGVVVGGGLAGVTAALRLADAGLDVTLLEGRPRLGGL
                     AFSFQRGDLTVDNGQHVYLRCCTGYRWFLDRIDAAHLAPLQDRLDVPVLDVGRAAGPRL
                     GRIRRTALPVPLHLAGGLAAYPHLSLAEKAAVGRAALALGRLDPADPELDRIDFATWLR
                     RHGQSDRAIEALWDLVGVATLNATAPDASMALAAKVFKTGLLSDPGAADIGWATVPLGD
                     LHDTLARKALDTAGVRTELRAKVGSLARTEDGRWSVERAGERIIADTVVLAVPQTETHD
                     LLPAGALDEPELLLDIACAPILNVHVIYDREVLRRPFFAAIGSPVQWVFDRTPSSGLKG
                     PGQYLAVSQSAAQAEIDLPVAELRSRYLPELERLLPAARGAGIRDFFVTRERTATFAPA
                     PGVGRLRPGPRTRLPGLQLAGAWTDTGWPATMEGAVRSGGAAADAALQDLGRPSGHPLQ
                     EAA"
     gene            complement(14710..15630)
                     /gene="hpnD"
                     /locus_tag="IE135_RS05010"
                     /old_locus_tag="GCM10010253_10130"
     CDS             complement(14710..15630)
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018492033.1"
                     /locus_tag="IE135_RS05010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_10130"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_199887676.1"
                     /sec_met_domain="phytoene_synt (E-value: 4.9e-59, bitscore:
                     194.7, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 3.9e-71,
                     bitscore: 234.6, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPPVQAAYSYCEAVTGQQARNFAYGIRLLPYEKRQAMSALYAFS
                     RRVDDIGDGELDAGTKRTRLESTRELLDRVRHGKVEEDDTDPVAVALADAARRFPLPLG
                     GLDELIDGVLMDVRGATYETWDDLKAYCRCVAGAIGRLSLGVFGTAPGARGADRAAEYA
                     DTLGLALQLTNILRDVREDAGNGRTYLPADDLAKFGCSAGFHRTTPPPGSDFAGLIHFE
                     VRRARALFAEGYRLLPMLDRRSGACVAAMAGIYRRLLDRIERDPEAVLRGRVSLPGHEK
                     AYVAVRGLSGLDARHISRRTARGRA"
     misc_feature    15599..15617
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.72"
                     /tool="antismash"
     CDS             complement(15660..>16387)
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=2
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018513262.1"
                     /locus_tag="IE135_RS05015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_10140"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_234427736.1"
                     /sec_met_domain="PT_phytoene_like (E-value: 9.8e-34,
                     bitscore: 111.8, seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="phytoene_synt (E-value: 2e-31, bitscore:
                     104.1, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="ARHLGLEPEQSDDRLAMLDALETDLRRVFATTGEEPHHPLLRNLR
                     PTVRRRALTPEPFLGLIEANRQDQKVRRYGTYAELAAYCELSANPVGRLVLALTGTTSP
                     ERVRRSDAVCTALQIVEHLQDVAEDLERDRIYLPAEDMERFRVTEADLAAPSAGASVRA
                     LIAYEAQRASDLLDEGPPLVGSVDGRLKLLLAGFVGGGRSALTAISAAGFDVLPGPPKP
                     TKPSLLREVGTVLRRARGER"
     gene            complement(15660..>16389)
                     /gene="hpnC"
                     /locus_tag="IE135_RS05015"
                     /old_locus_tag="GCM10010253_10140"
     assembly_gap    16390..16439
                     /estimated_length=50
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(16930..17715)
                     /locus_tag="IE135_RS05020"
                     /old_locus_tag="GCM10010253_10150"
     CDS             complement(16930..17715)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964853.1"
                     /locus_tag="IE135_RS05020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_10150"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_199887584.1"
                     /transl_table=11
                     /translation="MADDNAQGRIPTVIADDVHIVYRVNGAGGGRGSATAALSRMLRRG
                     KGEPRGVRKVHAVRGVSFTAYRGEAIGLIGTNGSGKSTLLRAIAGLLPTESGHVYTDGQ
                     PSLLGVNAALMSDLTGERNVVLGGLAMGMTQAEIRSRYQEIVDFSGINEKGDFITLPMR
                     TYSSGMAARLRFSIAAAKNHDVLMIDEALATGDRKFRIRSEERIRELRKEAGTVFLVSH
                     NNKSIRDTCDRALWLEKGELLMDGPTEEVLKAYERATGK"
     gene            complement(17708..18637)
                     /locus_tag="IE135_RS05025"
                     /old_locus_tag="GCM10010253_10160"
     CDS             complement(17708..18637)
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964854.1"
                     /locus_tag="IE135_RS05025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_10160"
                     /product="ABC transporter permease"
                     /protein_id="WP_006128930.1"
                     /transl_table=11
                     /translation="MSDTTHDGGVALGTPPSADEGLDAAQLAAKYGLTVSGARPGLFAY
                     MRQLWGRRHFILAFSRAKLTAQYSQAKLGQLWQVVTPLLNACVYYLIFGLILGTREGIP
                     HDVFVPFLVTGVFVFTFTQSSVMAGVRSISGNLGLVRALHFPRASLPISFSLQQLQQLL
                     FSMIVMVAVTVIFGSYPSLSWLLVIPALLLQFVFNTGLALVMARLGSKTPDLAQLMPFV
                     MRTWMYASGVMFSIPVMLKDKPAWIADVLQYNPAAIYMDLVRFAMIDGYGSENLPDHVW
                     AAGLGWAVLLGVVGFVYFWKAEERYGRG"
     misc_feature    complement(18633..18647)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.52"
                     /tool="antismash"
     misc_feature    18644..18658
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.73"
                     /tool="antismash"
     gene            complement(18739..19611)
                     /locus_tag="IE135_RS05030"
                     /old_locus_tag="GCM10010253_10170"
     CDS             complement(18739..19611)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018513265.1"
                     /locus_tag="IE135_RS05030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_10170"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_176734522.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3e-11, bitscore:
                     38.4, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLGAVIITMGNRPDELRALLDSVTAQHGDRIEVVVVGNGAPVPD
                     VPAGVRTVELPENLGIPGGRNVGIEAFGPCGADVDALLFLDDDGLLPNRDTAELCRQAF
                     AADPKLGIVTFRIADPETGVTQRRHVPRLRAADPMRSSRVTTFLGGANAVRTKVIAEVG
                     PLPEDFFYAHEETDLAWRALDAGWMIDYRADMVLNHPTTAPSRHAVYHRMVARNRVWLA
                     RRNLPAPLVPLYTGVWLLLTLVRRPSPPALKAWFGGFREGWTTPCGTRRPMKWRTVWRL
                     TRLGRPPVI"
     gene            complement(19620..20399)
                     /locus_tag="IE135_RS05035"
                     /old_locus_tag="GCM10010253_10180"
     CDS             complement(19620..20399)
                     /EC_number="2.7.8.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049651.1"
                     /locus_tag="IE135_RS05035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_10180"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_079149742.1"
                     /transl_table=11
                     /translation="MSRPSVAELRPVVHPPGVKDRRSGEHWAGRMYMREVSLRVDRYLV
                     NTRVTPNQVTYVMTLAGALAAPALLVPGVWGAVLGVVMVQLYLLFDCVDGELARWKKQY
                     SLSGVYLDRVAAYLCDAAVLVGLGLRAADIWGEGRIDWLWAFLGTLAALGAILIKAETD
                     LVGVARHQGGLPPVKEAASEPRSSGMALARKAAAALKFHRLILGIEASLVILVVAVVDS
                     IAGDLFYTRLTVAVMAGIALLQTLLHLVSVLASSRLK"
     gene            complement(20377..21438)
                     /locus_tag="IE135_RS05040"
                     /old_locus_tag="GCM10010253_10190"
     CDS             complement(20377..21438)
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007452391.1"
                     /locus_tag="IE135_RS05040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_10190"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_069740063.1"
                     /sec_met_domain="Fe-ADH (E-value: 2.2e-19, bitscore: 64.3,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 2e-10, bitscore:
                     35.2, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVVVDIRRGAMDDLAGLLADQRISSSGKLAIAISD
                     GSGRALRERLAPVLPGADWYPVSDGTIDSAVKLADGIKGNRYDAVVGLGGGKIIDVAKY
                     AAARVGLPMVAVATNLSHDGLCSPVATLDNDNGRGSYGVPTPIAVVIDLDVIREAPARY
                     VRSGIGDAISNISCVADWELAHEVNGEEIDGLAAAMARQAGEAVLRHPGGVGDDAFLKV
                     LAEGLVLTGISMSVAGDSRPASGACHEINHAFDLLYPQRAASHGEQVGLGACFAMHLRG
                     ARQESLLMASILRRHGLPVLPEEIGFSVDEFVKAVDYAPQTRPGRFTVLEHLNLSTDQI
                     RDAYADYVSTISS"
     gene            complement(21426..22163)
                     /locus_tag="IE135_RS05045"
                     /old_locus_tag="GCM10010253_10200"
     CDS             complement(21426..22163)
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955403.1"
                     /locus_tag="IE135_RS05045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_10200"
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="WP_015612697.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 8.7e-13, bitscore:
                     43.8, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVDGDKTVLDLTLANFAAV
                     GLTEVAIVVGYRKEAVYARKAELEATYGVTLTLIDNDKAEEWNNAYSLWCARDVIKRGV
                     ILANGDTVHPVSVEKTLLDARGKGQKIILALDTEKSLADEEMKVITEEGKGVQRITKLM
                     DPATATGEYIGVTLIEAEAAEELADALKTTFERDPDLYYEDGYQELVNRGFTVDVAPIG
                     TVTWVEIDNHDDLKKGREIACQY"
     gene            complement(22160..23914)
                     /locus_tag="IE135_RS05050"
                     /old_locus_tag="GCM10010253_10210"
     CDS             complement(22160..23914)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955402.1"
                     /locus_tag="IE135_RS05050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_10210"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_199887585.1"
                     /transl_table=11
                     /translation="MQTAADAGDAATLLAAVPAGRRVALVDPRFVGHVHALRLGLTDPR
                     FAAATVPGALTAQPEARGALLRALRRTTAAVGAGAPVVAPDTDPAPEDRTVPGRIAVAL
                     EAEGTAVKRPELGSLTATVPADATARAAAESARDAVDDEAVRLRSAVKAHDGFFTTFAI
                     SPYSRYIARWCARRGLTPNQVTTASLITALVAAGAAATGTRGGYIAAGILLLVSFVLDC
                     TDGQLARYSLQYSTMGAWLDATFDRAKEYAYYAGLAIGAVRGGDDVWVLALGAMVLQAC
                     RHVVDFSFNEANHDAVANTSPTAALSDKLDSVGWTVWARRMIVLPIGERWAMIAVLTAL
                     TTPRIVFYALLIGCALAACYTTAGRLLRSLTRRASRTDRAAQALADLADSGPLAQGVAA
                     VAPNLRGAFTAPAVALLGTLVMIGGALFLPYGSRLTVAAAAVYVVLSGLAVARPLKGAL
                     DWLVPPFFRAAEYVTILVLAARSDVPHAVPAAFGLVSAVAYHHYDTVYRIRGGTGAPPQ
                     WLVRTIGGHEGRTALVAVLAAVLTHASGFTTALTALAVAVALVVLVESIRFWVSSSAPA
                     VHDEGELA"
     misc_feature    24142..24157
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.5"
                     /tool="antismash"
     misc_feature    complement(24153..24168)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.59"
                     /tool="antismash"
     misc_feature    24154..24168
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 19.02"
                     /tool="antismash"
     gene            24253..25230
                     /gene="galE"
                     /locus_tag="IE135_RS05055"
                     /old_locus_tag="GCM10010253_10230"
     CDS             24253..25230
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (65-185). E-value:
                     2.1e-09. Score: 28.8. Matches aSDomain:
                     nrpspksdomains_IE135_RS05055_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128924.1"
                     /locus_tag="IE135_RS05055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_10230"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_069738219.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 6.7e-19, bitscore:
                     62.9, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 3.2e-12,
                     bitscore: 41.1, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWLITGGAGYIGAHVARAMVAAGERVVVLDDRSSGVVDRLPDAV
                     TLVEGSASDRALLDRVLAGHAVSGVVHLAAKKQVGESVEKPLLYYRENVAGLAVLLEAV
                     VAAGVRRFLFSSSAAVYGVPDVDLITEETPCLPINPYGETKLAGEWLVRATGKAHGLST
                     ACLRYFNVAGAAAPELADTGVFNIVPMMFERLTGGEAPRIFGDDYPTPDGTCIRDYIHV
                     ADLAEAHLAVARRLDETGAGDLTLNVGRGEGVSVRELADVIGEVTGSGLKPVVEPRRAG
                     DAPKAVASAARITGELGWTARRGVREMVESAWEGWCLHHPEARP"
     CDS_motif       24256..24342
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE135_RS05055_0001"
                     /evalue="9.40E-09"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE135_RS05055"
                     /protein_end="30"
                     /protein_start="1"
                     /score="27.9"
                     /tool="antismash"
                     /translation="TWLITGGAGYIGAHVARAMVAAGERVVVL"
     misc_feature    24294..24314
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 19.68"
                     /tool="antismash"
     aSDomain        24448..24807
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE135_RS05055_NAD_binding_4.1"
                     /evalue="2.10E-09"
                     /label="IE135_RS05055_NAD_binding_4.1"
                     /locus_tag="IE135_RS05055"
                     /protein_end="185"
                     /protein_start="65"
                     /score="28.8"
                     /tool="antismash"
                     /translation="AVSGVVHLAAKKQVGESVEKPLLYYRENVAGLAVLLEAVVAAGVR
                     RFLFSSSAAVYGVPDVDLITEETPCLPINPYGETKLAGEWLVRATGKAHGLSTACLRYF
                     NVAGAAAPELADTGVF"
     misc_feature    complement(25303..25317)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     gene            25413..26354
                     /locus_tag="IE135_RS05060"
                     /old_locus_tag="GCM10010253_10240"
     CDS             25413..26354
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049646.1"
                     /locus_tag="IE135_RS05060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010253_10240"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_069741209.1"
                     /transl_table=11
                     /translation="MGAGHDHGHAHGGPPPTGTAAAAHRGRLRIALAITLSVMVMEIVG
                     GVLSDSLALIADAAHMATDALGLGMALLAIHFANRPAALNRTFGFARAEILAALANCLL
                     LLGVGAYLIYEAVERFITPAETKGGLAIAFAAVGLVANVVSLSLLMRGQKESLNVRGAY
                     LEVMADTLGSIAVIVSAGIIMATGWQAADPIASLVIGLMIVPRTVKLLRETLDVLLEAA
                     PKGVDMAEVRAHITALPGVLDVHDLHAWTITSGMPVLSAHVVVRQEMLDSIGHEKVLHE
                     LQGCLGDHFDVEHCTFQLEPSGHAEHEARLCH"
ORIGIN
        1 ccgggaacag cggctgttcc tcttcgtcaa cgtgtccgcc ctgcaccagc cgaactggtt
       61 ccatctgccc ggcgcgaccc gcgaggcggg cgactcccgg gccacgcacg cggcggccct
      121 ggagtacgtg gaccggcaca tcggccggct cttcgccgcc gcgagcagcc gtcgccggtg
      181 cttcgccatc gtctgctccg accacggcac cgcctacggc gacgacggct acaccggtca
      241 ccggctcggc cacccggccg tctggaccgt cccgtacgcc cacttcttcc tcgaaccacc
      301 cgcaacgccc gaaccggggg ccgcccgatg acgatcacga ccagcaccac cgcgccgccc
      361 gccgtccggc cgtacgagag ttacgtctac gcgtatccgc acaagacggc ctaccggccg
      421 ctggcggacc gccccgccct gcggtcgctc tgggcggcgg agccgaagga cgccctctcc
      481 ctctacctcc acataccgtt ctgcgaggtc cgctgcggct tctgcaatct cttcacccgg
      541 atcggcgcgc cggagatgct gacgacgcgc tatctggacg cgctggaccg gcaggccctg
      601 gcggtgcggg aggcgctggg cgacgaggag ccggtgcggt tcgcggcggc ggcgttcggc
      661 ggcgggacgc cgacgttcct gaccgccggg gagctggagc ggctctgcga tatcgcggag
      721 aagcggatgg gcgccgatct gagcgcggtc ccgctgtccg tggagacctc gccctccacc
      781 gccacccccg accggttggc ggtgctggcc gaccggggca cgacgaggat cagcatcggt
      841 gtgcagagct tcgtggacga ggaggcccgg gcggccgtcc gtccccagcg ccgcgccgac
      901 gtggaagcgg cgctcggccg gatccgggac gcccggatcc cggtgctgaa catcgacctg
      961 atctacggca tcgacgggca gaccgagcgc agctggctcg cctcgctgga cgcggcgctg
     1021 gcctggcggc cggaggagct gtacctctat ccgctgtacg tgcgtccgct caccggtctg
     1081 caccgcatcg ggccggccgc gaccggcccg gaggcgcagg ccccggagga cgccgcctgg
     1141 gacgagcagc ggctgcggct gtacgcggtg gggcgggacc atctcctggc ccacggctac
     1201 gagcaggtgt cgatgcggat gttccggcgg accgacgccc cgcgcgagca ggagggcccg
     1261 gaggactacg cctgccagac cgacggcatg atcggcctcg gctgcggtgc ccgttcgtac
     1321 acgtccgccc tgcactactc cttcgactac gcggtggaca tgcgggagat ccggtcgatc
     1381 atcgaccgct tcaccgccac cgaggacttc tcccgcgccg aggtcggccg gtacgtcgac
     1441 gcggccgagg cgcgtcggcg gcacctgttg cagtcgctgc tccaggcggc ggggctgccg
     1501 gtggcggagt accgggcccg gttcggcacg gatccggggg aggacttccc ggccgagctg
     1561 gcggagttcg cggaccgggg ctggctggac gcggcggcgc cggacggtct gctcaggctg
     1621 tccccgtcgg gtctcgccca ctccgacgcg ctggggcccg cgctgttctc ccccggggtg
     1681 cgggcggcga tggccgcgta cgagaggaag tgaccgggcc gtggacctga cgattctcta
     1741 ccggggaccg ctcgcctcct gtgattacga ctgcccctac tgcccgttcg ccaagcggcg
     1801 ggacagccgt gcgcagctca cggcggaccg ggaggcgctg gagcggttca ccggctgggc
     1861 cgcggcacag acggccgacc ggctgtcggt gttgttcacg ccgtggggcg agggcctggt
     1921 gcgctcctgg taccggcggg cgctgaccga gctgtcccgg ctgccgcaca tcggccgggt
     1981 cgcgatccag acgaacctga gcggtcggac cgaatggctg gcggacgccg atccggagcg
     2041 gatcgcgctc tggtgcacgt accacccggg gcagaccccg tacgaccgtt ttctggggaa
     2101 atgccgtgag ctgtcggcga agggcatccg ctacagcgtg ggcgtggtgg ggttcgacga
     2161 gcatctcgac gaggcgcggc ggctgcgggc ggagttgccg ggcgaggtct atctctgggt
     2221 gaacgccgcc gaggggcaga cgtacacgga cgaggaggcg gcgcggtgga cggagctgga
     2281 tccgctcttc ccctacagcc gtgatccgca ccgctcggcg gggctgccct gccggacggg
     2341 cgagtcggtc atctcggtga acggggacgg cacggtgcgg cgctgccact tcgtcgaggc
     2401 ggagctgggc aatctctacg acggcagcta ccgccgggcg ctcggcccgc gggcgtgccc
     2461 gctcgccgag tgcgactgcc acatcggcta tgtgcatctg gagtcgctgc cgctgtacga
     2521 cgtgttcgcc ggcggtgtgc tggagcggat accggcggcg tccggcacgg gcacgccgcc
     2581 gggcgggttc gtcgtgccga acacgccccg gcgtgcgctt cccctgctgg agccctgagg
     2641 gggcaggccc tacagcggca gcaggtccgg gcgcttggcc tcgacgtggt cgccggagga
     2701 ctcgccgcgc agccgtcggc cgatccaggg caccaggtat tcgcgggccc actggatgtt
     2761 gtcgcgccgc tcgtcgaagg ggctgcgctg ggcctgcggc ggccagggct ggtcggggtc
     2821 ggcgggcacg tcgtggccga ggacctgggc ggcgcggagc gcgacgcggg tgtgtccctc
     2881 gggcgacagg tgcagccggt cggcgtccca cgcacggcgg tcctggacgg agcgcagcga
     2941 ccacaggtcc agcacggggc actggtagcg gtcggcgatg gcccggagat ggacgttgta
     3001 cgtggcgatc ttgccgcgca tgtggcgcag taccgggacg ccccgggtgt cgaagccggt
     3061 ggtgaccatg accgtgccga cggcgttgct cagctcggcg acggctcgct cgaagcgctc
     3121 ggcgagatcg tcggggtcgg tgccgggtcg gatgatgtcg ttgccgcccg cgcagaagct
     3181 gaccaggtcg ggggccagtt ccttggcgcg cgggacctgt tcctcgacga tctggtcgag
     3241 gagacgtcct cgtacggcga gattggcgta gcggaagtcc ccgtgcgggg agtcctcgtg
     3301 cggggcgtcc tcggagccgg cccggccggg ggccggcaac cggtcggcga ggagcaccgc
     3361 gaagcggtcc gcccagccga cgaaggtccc gtcggggccg gggtcgccga cgccctcggt
     3421 gaaactgtcg ccgatcgccg cgtacgaccc gatggtgtgc tgctggttgt ttctcgaatc
     3481 gtctgccaca aggacttatc ctgcatcgtc cgatgtgacc tacgcgaccg taatacgggg
     3541 ttgacgggtg gtgagataga ccacccggtc agttttcggt aaacccggaa taaagcgagg
     3601 ggcggtgcgc cgccgcgcac cgcccctcgc ggacacttct cgtcgccgct gggtcagagg
     3661 gagacgccgt gctgacgcag gtaggcgatc gggtcgacgt ccgaaccgta gctcgggccg
     3721 gtgcggacct cgaagtgcag gtgcgggccg gtggagttgc cggtggagcc ggagaggccg
     3781 atctgctggc cgccggtgac ggtctggccg accgagacgt tcagcgcgga ctggtgggcg
     3841 tactgggagt acatgccgtc ctcgtgctgg atgacgacct cgttgccgta cgcgccgctg
     3901 ttgccggccg agaccacggt gcccgggccg atggcgagga cgggggtgcc ggtggcggcc
     3961 tggaagtccg agccggtgtg gtagccgctg gaccagctgg cgccggaagc gcggtactgg
     4021 gtggtgacgt tggcgttggc cagcggggcg gaccagccgg agccggtggc ctcggcggcg
     4081 ccggtccgcg ccggggcgcc ggagccctcg gagtcgtcgg cggagatggt gtcgcccttc
     4141 ggggcttctt ccttcggcgc ggccttcggg gccggttcgg ccttcttcgg ggcggccttg
     4201 agggcggcgg acttctcggc cggggcggag cccttggcgc cgagggtcag cttcatgccc
     4261 gggtgaatca ggctggggtt gtcgccgacc gtggagcggt tgtcctggta gagcttctcc
     4321 cacccgccct tgagccggtg ctcggcggcg atcttcgaca ggtagtcgcc ggagaccacg
     4381 gagtacgtct tcggggcggc cttcgacgcg gcgggggcgg cggccggagc ggtgtgcgcg
     4441 gcggcgaccg aggcggcggc cggcttggcg gccggggcgg cctggtccgc ggcgttcgcg
     4501 gcggtggcgc cgatgagcgg gagggcgagt gcggcgccgc cggtcccggc ggcgaggacg
     4561 ccgcgggaga tcgggccgga cttcggacga cggtgcttac cctttgcggg catggggaag
     4621 ttcctctccg gcgcctgcga ggtgagctgt cgggttcggg ctggagatgc ccggtcgcgt
     4681 cgcggcgact tcacccctag ccggtccgga tcactccggc tcggcggctt acctggttcc
     4741 cccgctcctg ccacacgtga gtgggtgggt gcgaattccg ggcggcggca ggattaggcg
     4801 atccgtccgg attgacggtg accgtaaacc ggtcaggacg ggcggaacaa gccatcggtt
     4861 gcccggcgga atcagcgatt cgatatcgct ccggatttcc cgtcacactc cgtggatggc
     4921 ggatcttgaa tttccttacg ggcaacggga atgctcgacg gcgctctcac cacggaccgt
     4981 cacggatatg atcccgctca cctccgaaat cccatctccc ccattagcgg ggcatgttct
     5041 gcgaaatgca ccaatacgga catgccgcga gcggcaccgc ctgacacccg gtcagccggg
     5101 ccgcccggca cccgcccccg gggaggcgac catgatgatt ttccgtcgaa tcgatgtcgt
     5161 atcgtcacgg gagcgccctc gccggagagc cgcgccgacg cccgagaacc gaggagtccc
     5221 cgtgacgcag caggtgccgc agatcccgcc gacagaggtc gtgctgaccg gagtccgcaa
     5281 cttccgcgat gtgggcgggc tccccaccgc ggacgggcgg cgcaccgcct tcggccggct
     5341 ctaccgcagc ggccatctgg cacacgccac cgccgaggac gcggccttcc tcggcgggct
     5401 gggactgcac acgatcttcg acttccggca ctccgccgat caccggctcg acgggtacga
     5461 catcgagctg gccggtgtcc gcaatgtcag cattccgctc tcggacccgg ccgatggcgc
     5521 ggagttctgg cggctggtgg gcagcgggaa catcgagcag ctgcgctcgg tcctctccgg
     5581 cagcaaaggc gtcgaccgca tgatccggat gtaccgcgcg acgatcgagg accgcaccgc
     5641 cgagcacagc cgggtcctgc acgccctggc cgaggacagc gtcccggcgc tgatgcactg
     5701 cgcggcgggc aaggaccggg ccggcctctc gatcgcggtc gccctgctcg cggtcggcgt
     5761 cgtgccggag gcgatcgagg aggactacct caagtccaac gatctccacc gccggtacaa
     5821 ggtgaagcgc tccgacccgt ccggcgccgg catgtcgccc gaggtgctgg agctgctgga
     5881 cccgctgttc ggggcgcggc ccgcctatct cgcggcggcc ttcgcggcca tcgaggagaa
     5941 ctgggggacg acggaccgct atctgtccga ggggctgaag ctctcccccg cgacgcggga
     6001 gcggctgcgc gagcggctgc nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnngaa
     6061 ggccgcgatg atgtggcccg ccaccagata ggcgaagagc cggatgatga cgccgcgcgg
     6121 catccgcttc tcctgcgggt cctcgttcgc gcggcgtccg gggcccagcg ggtcgtagtg
     6181 ctcggaatcg gacatgacgg tcctctctgc cggcctcgcg gccggtggca tgaagggtgg
     6241 ggccggcggg agcggccggt cagcgcgagt gcagtccgct gccgaggcag agctcggcag
     6301 cggggctctg cagcagggag tggacgaaga gcagctccgc gccgcggcgg tcgacggcca
     6361 cgatccggtg cggggtgagc gagtcgaagt gggcgctgtc gccgggttcg aggtcgtgga
     6421 cggtgtcgcc gagaccgacc cgcagccggc cctccaggac gtagagccac tcctcgccgg
     6481 ggtggacccg gaccaggtcg ccctgagccc cgtacgggac gcgcacccgc agcgcctgca
     6541 tcgcgcggcc ggagccgccc gcccgccggt acatccaacc gtcggcctcc gcgccctcga
     6601 agccgccgcc gcggatgatc gcgtcccgtt cgggcggctg ctcgccgagc agctcggaga
     6661 ccgtcgtacc gtagatgcgg gcgagcccca gcagcatggg cagcgagggc tgcctgcggc
     6721 cggtctccag ccgggagaga tgggccggcg agagcccggc ccgctgggcc gcggtctcca
     6781 gggtgaagcc gcgggcgcgg cgcagatcgc gcagtcgggg tgcgacgccg gggagctcgt
     6841 ccggcgcccc ttcgtccgga gggttcatat gcctattggg ccaggagttt tcctcagagg
     6901 caaataactt gcctctgagg caaatgcgag gtcagcggtt ggcgacggcc tgcttgacga
     6961 gggtccggcc gaagtcccac atcagtccgc cgccgctgtg cgcctcctcc atgacggacg
     7021 tgaacgccgc cacgaaacgg tccacctcct cgtccccgat gaccaggggc ggaatcagtt
     7081 tgatcacttc caggtggtcg ccggagacct gggtgaggat ccggtgcttc tggaggagcg
     7141 gcacgacgat catctgagcg aagagtccct tgcgggcggc ctggagcatg gtccagcggc
     7201 tgcggagctt cagcgaggag ggccggccga actcgatgcc gatcatcagc ccgcgcccgc
     7261 gcacctcgtg cagcagttcg tagcggtcca ccagggcggc cagccgctca cgcagcagat
     7321 cgccggtgcg ccgggcgttc gcgacggtct cctcgtcctc catcaccgtc aggacggcga
     7381 gcccggcggc catcgcctgg gcgttggagc cgaagctcgc ggagtggacg aggacccggt
     7441 ccatggagga gtagaccttg cggaagatcc agtccttgcc gagggtcgcg ccgaccggca
     7501 catagccgcc ggagagggcc ttggccacgc acacgaggtc gggctccacc ccctcctcgt
     7561 gctggtaggc gtagaagtcc ccggtacgcc ccaggcccgt ctggacctcg tcggcgatca
     7621 gcagcgcctt gtgccggtgc agcagctcct gggcctcgcg cagatagccg ggcggcgcgg
     7681 ggtgcacgcc cttgccctgg atcggctcga cgatcagcgc cgcgacgtcg ccccgcttca
     7741 gctcacggcg cagcgcgtcg aggtcgccga gcggaacggc cgtgtcgggg agcagcgggg
     7801 cgaagccgtc gcggaagccg ctctccccgt tgacggacag cgagcccgtg gtgagcccgt
     7861 ggaaggcgtg gtcgcagtag aggacccggg atttcccggt ggcgtaccgg gcgaacttca
     7921 gcgccgtctc gaccgcttcg gtgccgctgt tgccgaagaa gacccggtcc aggtgcgggc
     7981 tgtgggtcaa cagcttctcc gcgagcagtc cgggaagcgg ctgacagtcg aagcgggtga
     8041 ggtcggcgag ctgggcgtcg agcacgtcgt ggagggcctt ggctacgacc gggtggtgcc
     8101 ggccgatgcc catgacgcca aatccggcga gcatgtcgag gtagtcgttg ccctccgcgt
     8161 cccagaagta cgcgccctgg gcccgctcgt agaccttgtc gaagccgatg gtgtgcagca
     8221 tgcgcggcag ctggtggttg agatggcgcg catgcagctc gtaccgctcg gcgccgcgct
     8281 cggccaggag tcgtcccagg tcgaagccgc ccggcccgcc gtccgtcacc ggttgccgcc
     8341 cacgctctcc cgcgccgcgc gcagggactc cttgagcgat cccatggtgg ccagcacggc
     8401 cgtgggttcg tagccgcagt gcgccatgca gttggcgcag cgcgggtcct tgccccgccc
     8461 gtacttctcc cagtcggtct cctcgatgag ctgacggtac gtcggtacgt agccgtcgct
     8521 catcaggtag caggggcgct gccagccgaa gagcgagtag ttggggatgg cccaggcggt
     8581 gcacgggaag tccgccttgc cctccaggaa gtccaggaag agcggcgagt ggttgagccg
     8641 ccagcgggct cggttgccgc ccgcgaaggc cttcttgaag agttcgcggg tctgctcgac
     8701 gccgaggaag tgctcctggt cgggggcctt ctcgtaggcg taggcgggag agatcatcat
     8761 ctcgtcgacc ttgaggtcgt cgttgaggta gttgaggacc tcgatgatgg tctgcggggt
     8821 gtcggtgttg aagaaggtgg agttggtggt gacacggaag ccgcgcgcct tggcctcctt
     8881 catcgcggcg acggcctcgt cgaagacgcc ttccttggcg accgactcgt cgtgccgctc
     8941 gcgcagtccg tcgatgtgca cggcgaaggc gaagtacggg gacggggtga acttgtcgag
     9001 cttcttgcgc atcagcatgg cgttggtgca gaggaagacg tacttcttcc gcgcgacgag
     9061 ctggcgcacg atctcgtcga tctgcggatg catcagcggc tcgccgccgg cgatggacac
     9121 catgggggcc ccggattcga ggaccgcgcc caccgcctgg gcgaccggca tgcgctgctt
     9181 caggacaccg gccgggtgct ggatcttgcc gcatccctcg caggcgaggt tgcaggcgaa
     9241 caacggctcc agctcgacga tcagcgggaa cttctcacgc ttgcggagct tctgttcgaa
     9301 gagatacgtc gcaaccttga tggtctggcg gagcggcatg gccatctggc tcacctcctg
     9361 gggagcagta aagatcggtg ccattcgtag aaagccggaa ggacggcacg aagaacgcgg
     9421 aacgccgata ttccaccgcg tacggtgccg atgcggacga gctcatgctc tggagcgtcc
     9481 acgaccaccc ggacggccgc aaccgggcgc ggtccgtgac acagggcggt acgcagtgtc
     9541 gcggcggact ccatgtccac cgcgatggcc ccgcccgccc gcagcgcggc ccgctcgggc
     9601 ccccgtacga cgtggtcgga gccggtcagc ggaccggtgt ggaccctgcg gccgggcagg
     9661 gcgcgggtca gcgcggcgac caggacgccg gtgcccgtgc agggggtggt gccgtcggcg
     9721 tcccgggtct cctcggcgac gacgaggtcc ccggggtgca tccccggggc gaggccggcg
     9781 cagaagccgg aggcgatgac ggcggcatcg gacaacccgt cggggccgcc cagaaggcgc
     9841 gccacggccg cctccgccgc ccgggggccc atcccggtgc gcaggatgcg gaccgggccc
     9901 ggggcgcccc tgccgctgcg cagggccacc tgctcgatgc cgagggcgca ggcgaccagc
     9961 agcggcgtca cggggctccc ggaccctcgc ggatcgccca tcacatcccc tcggcggcgt
    10021 ccgcgcggtc cgcgaacggg tcgccgtaca cataccgccc gagtgcggtg agggggaaca
    10081 cctggcggta gaggtggtag ttgatcgaga agtcccaggg gaatccggtg ccggtgaaat
    10141 acggctcgtc ccaggagccg tcggcctgct gcgcctcggt cagccagatg atgccccggg
    10201 tgacggaggc ggtgtcccgg cgtcccgcgg cgaggagggc gagcagcgcc caggcggtct
    10261 gggaggcggt ggactcaccg tgcccgatcc acttctcctc ctggtaggag cgcaggtcct
    10321 cgccccagcc gccgtcgtcg ttctggacgg actccagcca gtcgacggcc cggcggatcg
    10381 cggggtggcc cgcgggcagt ccggcggtga tcagggcggg caccacggaa ccggtgccgt
    10441 agacgtagtt gacgccccag cggccgaacc aggcgccgca cgcctcctgt tcggcgagca
    10501 gccactcgat gccctcgcgg gtacgggggt ggttcgcgag cccctcgaca gcgagcatct
    10561 ccacgacgtg gccggtgacg tcggccgacg ggggatcgat gacctcgccg aagtcgcaga
    10621 agggcagccg gttggggaag gggctggtgt tgtcggcgtc gaacgcgccc caggccccgt
    10681 tgcgggactg catcccgagg ttccagcgga ccccgcgggc gatcgccgcc tcgagccggg
    10741 cggggtcggg gtggcgcacc cggcgcagcg ccaggacgac ctcggcggtg tcgtcgatgt
    10801 ccgggtagtt gtcgttgtgg aactcgaacg cccaaccgcc cggggccagt tcgggtttgc
    10861 ggaccgacca gtcgccgggg cgggtgatct cctcggccag catccagtcg gcggccttca
    10921 ccagggcggg gtggtcgggt ctcaggccgg cgtcggccag cgcgatggtg gccaggcagg
    10981 tgtcccagac gggcgactgg caggcctcga tcatgcgggc gccgtcctcg cggtgtacgg
    11041 cgaaccggtc gagcgaggcc aggccggcct tcatcaccgg gtggtcgagg tcgtagccga
    11101 gcaggtgcag ggcgatgatc gagtagacgg cgggcggctg gatcccgccc cagcagccgt
    11161 cgttctcctg gcgttcgatg atccagcggg cggccacgtt catcgcgata cggcgcagcg
    11221 ggcgcggggc gatcttgtgg tagaggtgca gccctttatc gaggcgctgg aagagcccgt
    11281 cccaactggt gggcggggca agcttcctgg ccgggttggg gtggtccggg tcggtgtgca
    11341 gctcgtccag ggcgaagggg gcggggcgca cggggcgttt cgcggagacg atggtgagcg
    11401 gcacgatggt ctgccgggcc cagcagccga agtcatagat gttgagcggg acccgcttgg
    11461 ggaggaacat cagctcgggc gggagttcgg ggaggtcgtc ccatttccac cagccgaaga
    11521 gggccagcca gatgcgggtg aagacgcggg cggcggcgat gcctccctgg tcccggatcc
    11581 agccggaggc gcgggccatg tgcggttcgt cggggcggtc cccggccagc cgcagggcga
    11641 cgtacgcctc gatcgtggcg gagaggtccc cgggtccgcc gtagaaggtg ttccaggtgc
    11701 cgtcgccgag ttgttcgccg cggatgaaga gggcggcggc ccgggtggtc ccggggtcct
    11761 ggattccgag gaactggcgc aggagcaggt cctcggcgtc catcgtgacg ttggtggcga
    11821 ggtcgccctt ccaccagccc tgctcgtcct gtctgccgag gaggtgctcc acggagcgtt
    11881 ccgcggcccg ccgcgcgatg tcggtgacat cgttggcggc ggttctcgtg tcggtcggat
    11941 cgtccggtgc cccggtggtg ttcgcggccc cggtcgatcc gtcggtcgtc gctgtcatga
    12001 gcttcccctt acgtgcagtc gtctctctgc tgtgctgggg tctccgtcgg ccggcgcccc
    12061 gatgagggcg ccggccggcg actgcgagtc atatggagaa agtgatcatc tctttcgtac
    12121 caccacgaag tcggcgagct cggtgagctg cttccgcacc cggtggggca tgtcgacggc
    12181 gtgcagcgcc tcgatggcga cggcgtgctg gcgacgggct tcctgggcgg tccactcgcg
    12241 gccgcccgcc tcctcgatga gcgccgcgcg ggcggcgaac tcctcttcgg agaagctgtc
    12301 gaagtcgttg ctcttggcgt cggcggcgag cagttcgccg aggcgctcgg aggcctcgcc
    12361 gcccgcggcg agcgcggcga cgaccggcag ggacttcttg cgctggcgca ggtcgctcca
    12421 ggtctgcttg ccggtggact ccgggtcgcc ccagatgccg agcaggtcgt cgacggcctg
    12481 gaaggcgagg ccgaggtggt agccgtacgc ctccagggtg tcggcggtgc ggtcgtcggc
    12541 gccgccgagc accgctccga tggagacggc gcaggccagc agggcgccgg tcttgttgcc
    12601 ctccatctcc aggcactcct cgacggtgac ccgctcgcgg tgctcgtagg agatgtcctg
    12661 ggcctgcccg tcgatgagct tgcgggtggc ggtggtcagc cggcgggccg cgcggcccgc
    12721 ctggacggtg ccgagctcga ggagcaggtc gtaggcgagg gcgaagagcg cgtcgccgac
    12781 caggatcgcc tgggcggggc cgtgcacctt ccatacggtg tcgcggtggc ggcgctgttc
    12841 gtcgccgtcc atcaggtcgt cgtgcagcag agagaagttg tgcacgagct cgacggccac
    12901 ggcgccgggg ataccggcct ccgccggggc gcccgccgcc tcggcggaca gcagggcgag
    12961 cgcggggcgc acggccttgc cgccgtctcc gtccgagggc cgcccctctg cgtcgatcca
    13021 gccgaagtgg tacgcggcga cggtgtccat gggcggcgcg agccggtcca cggcagcccg
    13081 caggaccggc gctgacaggg ctcgtccgcg ctccagaagc gcggtgacgt ccgcggtgtc
    13141 agccacggtg tcgaaagccg gattcgccgg ggtcacagac tctcctcttg ttccggtggt
    13201 actgctcatg ccgcctcctg aagcggatgt cctgaggggc ggccgaggtc ctggagggcc
    13261 gcgtcggcgg cggctccgcc actgcgcacg gcaccctcca tcgtcgcggg ccagccggtg
    13321 tcggtccagg ccccggccag ctggaggccg ggcagccggg tacgggggcc ggggcgcagc
    13381 cgcccgacgc ccggggcggg cgcgaaggtg gcggtgcgct cccgggtgac gaagaagtcg
    13441 cggatgcccg cgccgcgggc ggcgggcagc agccgctcca gctcgggcag gtagcgggag
    13501 cgcagttcgg cgacggggag gtcgatctcg gcctgggcgg ccgactggga gaccgccaga
    13561 tactgcccgg ggcccttgag gcccgaggag ggggtgcggt cgaagaccca ctggaccggg
    13621 gagccgatcg cggcgaagaa cggccggcgc aatacctcgc ggtcgtagat gacgtgcacg
    13681 ttgaggatcg gggcgcatgc gatgtcgagc agcagctccg gctcgtccag cgcgccggcg
    13741 ggcagcaggt cgtgggtctc ggtctgcggc acggccagca cgacggtgtc ggcgatgatc
    13801 cgctcccccg cgcgctcgac gctccagcgg ccgtcctcgg tgcgggcgag ggagccgacc
    13861 ttggcgcgca gttcggtgcg gacgcccgcg gtgtccaggg ccttgcgggc gagggtgtcg
    13921 tgcaggtcgc cgagcgggac ggtcgcccag ccgatgtcgg cggcgccggg gtcggagagc
    13981 aggccggtct tgaagacctt cgccgcgagc gccatcgagg cgtccggagc ggtggcgttc
    14041 agggtggcga cgccgacgag atcccacagg gcctcgatgg cgcggtcgga ctggccgtgc
    14101 cggcgcagcc aggtggcgaa gtcgatccgg tccagctcgg ggtcggcggg gtcgaggcgg
    14161 cccagcgcga gggcggcccg gcccacggcc gccttctcgg cgagcgagag gtgcggatag
    14221 gcggcgaggc cgcccgccag gtggagcggt acgggcaggg cggtccggcg gatccgtccg
    14281 aggcgtggtc cggcggcccg gccgacgtcc agcacgggca cgtcgaggcg gtcctggagg
    14341 ggggccaggt gggcggcgtc gatccggtcg aggaaccagc ggtagccggt gcagcagcgc
    14401 aggtagacgt gctggccgtt gtcgacggtg aggtcgccgc gctggaagga gaaggcgagg
    14461 ccgccgaggc ggggccggcc ttccaggagg gtcacgtcga gtccggcgtc ggcgaggcgg
    14521 agtgccgccg tgaccccggc gaggccaccg ccgacgacca cgccgacggg gcgcgggctc
    14581 tcgtcgctca tgcctgcccc tcccgtcggg tcgtggctgt ctgccgggtc ctcaccttgc
    14641 agatcgtcgc agtcagtgac gcgtcgggcc accggagggt tgccccgggg ccggagccgc
    14701 gcggccgcat caggctcgcc ccctggcggt gcgccgcgag atatggcggg cgtcgaggcc
    14761 ggacaggccg cgcaccgcga cgtaggcctt ctcgtggccg ggcagggaga cccggccgcg
    14821 caggacggcc tcggggtcgc gctcgatccg gtcgaggagg cggcggtaga tcccggccat
    14881 cgccgcgacg caggcgccgc tgcggcggtc gagcatcggc agcagccggt agccctcggc
    14941 gaacagggcg cgggcgcggc ggacctcgaa gtggatgagg ccggcgaagt cggacccggg
    15001 gggcggggtg gtgcggtgga acccggccga gcagccgaat ttggccaggt cgtcggcggg
    15061 caggtaggtg cgcccgttgc ccgcgtcctc gcggacgtcg cgcaggatgt tggtgagctg
    15121 gagggcgagg ccgagggtgt cggcgtactc cgcggcgcgg tcggccccgc gggcgcccgg
    15181 cgcggtgccg aagacgccga ggctgaggcg tccgatggct ccggcgacgc accggcagta
    15241 ggccttcaga tcgtcccagg tctcgtaggt cgcgccccgt acgtccatca ggacgccgtc
    15301 gatcagctcg tcgagtccgc cgagcgggag cgggaagcgg cgggccgcgt cggcgagcgc
    15361 gacggcgacc gggtcggtgt cgtcctcctc gaccttgccg tgccggaccc ggtcgagcag
    15421 ctcgcgggtg ctctccagcc gggtccgctt ggtcccggcg tcgagctccc cgtcaccgat
    15481 gtcgtcgacc cgacgggaga aggcgtacag cgccgacatg gcctgccgct tctcgtacgg
    15541 cagcagcctg atgccgtagg cgaagttccg ggcctgttgt ccggtgaccg cttcgcagta
    15601 actgtatgcg gcctgcaccg gcggcgacat gtacgtcgtc tgtccctcca cggtccggct
    15661 cacctctctc cacgcgctct tcgcaagacg gttcccactt cacgcagcag gctgggcttg
    15721 gtgggcttgg gtggtccggg cagtacgtcg aacccggcgg ccgagatcgc cgtgagcgcg
    15781 ctgcggccgc ccccgacgaa accggcgagg agcagtttca gcctgccgtc gacgctgccc
    15841 accagcggag gcccctcgtc cagcaggtcg ctcgcacgct gggcctcgta cgcgatcagg
    15901 gcgcgcacgg aggctccggc ggagggtgcc gccaggtcgg cttcggtgac ccggaagcgc
    15961 tccatgtcct cggcgggcag atagatccgg tcgcgttcca ggtcctcggc gacgtcctgg
    16021 aggtgctcga cgatctggag tgcggtgcag accgcgtcgg agcggcggac gcgttcgggg
    16081 ctggtggtgc cggtgagggc gaggaccagg cggccgacgg ggttcgcgga gagctcgcag
    16141 taggcggcga gctcggcgta ggtgccgtag cggcggacct tctggtcctg gcggttcgcc
    16201 tcgatcaggc cgaggaaggg ctcgggggtc agtgcgcggc ggcgcacggt ggggcgcaga
    16261 ttgcgcagca gggggtggtg cggctcctcg ccggtggtgg cgaagacccg gcggaggtcg
    16321 gtctccaggg cgtcgagcat ggcgaggcgg tcgtcgctct gctccggctc caggccgagg
    16381 tggcgggcgn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnng
    16441 gggaagttct cgtccgcggc cttgccgagg gtggcgtcgc cgatgtgcgc cgcgggggtc
    16501 gaggtcactg cggaccaccc ggcgcgggga cggcgagacc acgtcggagc tggagatttt
    16561 ccgtcattgc cgtcacatct cccgttctac actgccgacc caaaacaacc cttttcggac
    16621 acgccgctca gtcttccccg tgcactgcgg cagagcctcg gtgccgcggc gtatcgccct
    16681 acttgccatg aatcagcacc gctccagctt acgttgtaca gctcgcaggg gatcggcggg
    16741 gtggagcgtc cgccaccgct tcccggccgc acctgtcaac cttccccggg cacggctgac
    16801 ttgacgtcat ccgccgggag gagatcggac ctggccccct actgcggagg gcctgcccgg
    16861 caacgggcac cgcacggccc ccgccggacc ggtccggcgg gggccacggg atgggctcgg
    16921 gggctcgggc tacttgcccg ttgcgcgctc gtacgccttg aggacttcct cggtggggcc
    16981 gtccatcagc agctcgccct tctccagcca cagcgcgcgg tcgcaggtgt ccctgatcga
    17041 cttgttgttg tggctgacca ggaagacggt ccccgcctcc ttgcgcagtt cgcggatccg
    17101 ttcctcggag cggatgcgga acttgcggtc accggtggcc agcgcctcgt cgatcatgag
    17161 gacgtcgtgg ttcttggcgg cggcgatcga gaaccgcagg cgcgccgcca tgccggagga
    17221 gtacgtccgc atcggcaggg tgatgaagtc gcccttctcg ttgatgccgg agaagtcgac
    17281 gatctcctgg tagcgggagc ggatctcggc ctgggtcatc cccatggcca gaccgcccag
    17341 caccacgttg cgctcgccgg tcaggtcgct catcagcgcc gcgttcacgc cgagcagcga
    17401 gggctggccg tcggtgtaca catggccgga ttcggtcggc agcagtccgg cgatggcccg
    17461 cagcagcgtc gacttgccgg agccgttggt gccgatgagg ccgatggcct cgccgcggta
    17521 ggcggtgaag gagacgccgc gtacggcgtg caccttccgg acaccgcgcg gctcgccctt
    17581 gccccgccgc agcatgcggc tcagcgcggc ggtggcgctg ccccggccgc cgcccgcgcc
    17641 gttgacccgg tagacgatgt gcacgtcgtc ggcgatcacc gtggggatgc gcccctgcgc
    17701 gttgtcgtca gccacggccg taccgctcct ccgccttcca gaagtacacg aatcccacga
    17761 cgcccagcag caccgcccag cccaggcccg cggcccagac gtggtccggc aggttctcgg
    17821 agccgtagcc gtcgatcatg gcgaagcgga ccaggtccat gtagatcgcc gccgggttgt
    17881 actggagcac gtccgcgatc caggccggct tgtccttgag catcaccggg atggagaaca
    17941 tgacgcccga ggcgtacatc caggtgcgca tcacgaacgg catcagctgc gcgaggtcgg
    18001 gggttttcga gccgagccgc gccatgacga gggccaggcc ggtgttgaag acgaactgga
    18061 gaagcagggc gggaatcacc aggagccacg acagcgaggg gtagctgccg aagatgacgg
    18121 tgaccgcgac catcacgatc atcgagaaga gcagctgctg gagctgctgg agcgagaagg
    18181 agatggggag cgaggcccgg gggaagtgga gggcccggac caggccgagg ttgccggaga
    18241 tcgaccggac acccgccatc accgagctct gggtgaaggt gaagacgaag acgccggtga
    18301 ccaggaacgg cacgaagacg tcgtggggga tcccctccct ggtccccagg atcaggccga
    18361 agatcaggta atagacacag gcgttcagca ggggcgtgac cacttgccac agctggccca
    18421 gtttggcctg gctgtactga gcggtcagct tcgcccggga gaaggccagg atgaagtggc
    18481 gtcggcccca gagctgtcgc atgtacgcga acagccccgg tcgggcgccg ctcacggtca
    18541 ggccgtactt ggcggccagc tgggccgcgt cgaggccctc gtcggcggac ggcggggtcc
    18601 cgagggctac cccaccgtcg tgggtcgtgt cactcacaag ttgagactct cgtcttcacg
    18661 cgcagccagt cgcgggtgcg gctcaggcgg acaggttccg gaaagaaaat acgcctcatg
    18721 ctctcagagg taagcgtctc agatgaccgg aggtcggccc agcctcgtca gccgccacac
    18781 cgtacgccac ttcatcgggc gccgggttcc gcaaggggtc gtccagcctt cccggaatcc
    18841 gccgaaccag gccttcagcg cgggcggcga cgggcgcctg accagggtca gcaacagcca
    18901 gaccccggtg tagagcggta ccagcggggc gggcaggttc cggcgggcga gccagacccg
    18961 gttgcgggcg accatgcggt ggtagaccgc gtgccgggac ggggcggtgg tggggtggtt
    19021 cagcaccatg tcggcgcggt agtcgatcat ccagcccgcg tccagcgccc gccaggcgag
    19081 gtccgtctcc tcgtgggcgt agaagaagtc ctcgggcagg gggccgacct cggcgatgac
    19141 cttggtgcgt acggcgttgg cgccgccgag gaaggtcgtc acccgcgagg agcgcatcgg
    19201 gtcggcggcc cgcagccggg gcacgtgccg ccgctgggtg acgccggtct ccgggtcggc
    19261 gatgcggaag gtgacgatcc cgagcttcgg gtccgccgcg aaggcctgcc ggcacagctc
    19321 ggcggtgtcc cggttcggca gcagcccgtc gtcgtccagg aagagcagcg cgtccacgtc
    19381 cgccccgcag ggtccgaacg cctcgatgcc gacgttgcgg ccgccgggga tgcccaggtt
    19441 ctcgggcagc tccaccgtgc gcaccccggc gggcacgtcg gggaccgggg cgccgttgcc
    19501 gacgaccacg acctcgatcc ggtcaccgtg ctgggcggtg accgaatcga ggagggcgcg
    19561 gagctcgtcc gggcggttgc ccatggtgat gatcaccgcg cccagtttca tgggacgggt
    19621 cacttcagcc tgctggacgc caggacggac accaggtgca gcagggtctg cagcagcgcg
    19681 atgccggcca tgaccgccac ggtcaggcgg gtgtagaaga ggtcgcccgc gatcgagtcc
    19741 acgacggcca ccacgaggat caccagggac gcctcgatac cgaggatcag ccggtggaac
    19801 ttgagcgcgg cggcggcctt gcgggccagc gccatcccgg aggagcgcgg ctcggacgcc
    19861 gcctccttca ccggcggcag cccgccctgg tgacgggcca cgcccaccag gtccgtctcg
    19921 gccttgatca ggatcgcgcc gagcgccgcg agcgtcccga ggaacgccca gagccagtcg
    19981 atccggccct cgccccagat gtcggcggcc cgcaggccga ggcccacgag gaccgccgcg
    20041 tcgcacagat aggcggcgac ccggtccaga tagaccccgc tgagcgagta ctgcttcttc
    20101 cagcgggcca gctcgccgtc cacgcagtcg aagagcagat agagctggac catcaccacg
    20161 ccgagcacgg cgccccagac gccaggcacc agcagcgccg gggcggccag ggctccggcc
    20221 agcgtcatga cgtacgtgac ctggttcggc gtgacgcggg tgttcaccag gtagcggtcc
    20281 acgcgcagcg agacctcgcg catgtacatg cgcccggccc agtgctcgcc gctgcgccgg
    20341 tccttcaccc ccggggggtg cacgaccgga cggagttcag ctactgatgg tcgagacata
    20401 gtcggcgtac gcgtccctga tctgatcggt ggacaggttg aggtgctcca ggaccgtgaa
    20461 gcgtcccgga cgcgtctgcg gcgcgtagtc gacggccttg acgaactcgt cgacgctgaa
    20521 cccgatctcc tccggcagga ccggcagacc gtggcggcgc agtatcgatg ccatcaggag
    20581 ggactcctgg cgggcaccgc gcagatgcat ggcgaagcag gcgccgaggc cgacctgttc
    20641 gccgtggctg gccgcgcgct gggggtagag caggtcgaag gcgtggttga tctcgtggca
    20701 ggcgccggag gccggccgcg agtcgcccgc gaccgacatc gagatgcccg tcagcacgag
    20761 tccctcggcc agcaccttca ggaaggcgtc gtcgccgaca ccgcccgggt ggcgcagcac
    20821 ggcctcgccg gcctggcggg ccatcgcggc cgcgagcccg tcgatctcct cgccgttgac
    20881 ctcgtgggcc agctcccagt cggcgacgca ggagatgttc gagatcgcgt cgccgatgcc
    20941 ggagcggacg taacgggcgg gcgcctcacg gatcacgtcg aggtcgatga ccacggcgat
    21001 cggggtgggg accccgtagg agccgcgtcc gttgtcgttg tccagcgtgg cgacgggcga
    21061 gcacaggccg tcgtgcgaga ggttcgtcgc gacggcgacc atcggcagcc cgacccgcgc
    21121 cgcggcgtac ttcgccacgt cgatgatctt gccgccgccg aggcccacca cggcgtcgta
    21181 ccggttgccc ttgatgccgt cggcgagctt caccgcggag tcgatcgtgc cgtcggagac
    21241 cggataccag tcggcacccg gcaggaccgg agcgagcctc tcccgcaggg cgcgcccgga
    21301 tccgtcgctg atcgcgatgg cgagcttgcc cgaggaggag atccgctgat cggccagaag
    21361 acccgccaga tcgtccatgg cgccgcgccg gatgtcgacg acgaccgggg acggaatgag
    21421 ccgggtcagt actggcacgc gatctcccgg cccttcttca ggtcgtcgtg gttgtcgatc
    21481 tcgacccagg tcacggtgcc gatgggggcc acgtcgacgg tgaagccgcg gttcacgagc
    21541 tcctggtagc cgtcctcgta gtagaggtcg gggtcgcgct cgaaggtggt cttcagcgcg
    21601 tccgccagct cctcggcggc ctcggcctcg atgagggtga ctccgatgta ctcaccggtc
    21661 gcggtggccg ggtccatcag cttcgtgatg cgctggactc ccttgccctc ctcggtgatg
    21721 accttcatct cctcgtcggc aaggctcttc tcggtgtcca gggcgaggat gatcttctgg
    21781 cccttgccgc gggcgtccag gagcgtcttc tcgacggaga ccgggtgcac ggtgtcgccg
    21841 ttggcgagga tcacaccgcg cttgatgacg tcacgggcgc accagaggga gtaggcgttg
    21901 ttccactcct cggccttgtc gttgtcgatg agcgtgaggg tgacgccgta cgtcgcctcc
    21961 agctcggcct tgcgcgcata gacggcttcc ttgcggtagc cgacgacgat cgcgacctcg
    22021 gtgagcccga ccgccgcgaa gttggccagc gtgaggtcga ggaccgtctt gtcgccgtcg
    22081 acagggacga gcgccttggg gagcgtgtcc gtgtaggggc gcagacgtcg tcctgcaccg
    22141 gctgccagta cgaggccgat catgcgagtt ctccttcgtc gtgtacggcg ggcgccgagg
    22201 aggacaccca gaagcggatg gactccacga gcaccaccag agccacggcg accgcgagcg
    22261 cggtcagggc cgtggtgaaa cctgaggcgt gggtgagtac ggcggcgagg acggccacca
    22321 gcgcggtgcg gccctcgtgt ccaccgatcg tccgcaccag ccactggggc ggcgcgccgg
    22381 tgcctccgcg gatgcggtac accgtgtcgt agtgatggta ggcgacggcc gagaccagcc
    22441 cgaaggccgc cggaacggcg tgcggtacgt cgctgcgggc cgccagcacg aggatcgtga
    22501 cgtactccgc cgcccggaag aacggcggca ccagccagtc gagcgcgccc ttgagcgggc
    22561 gggcgacggc gaggccggag aggaccacgt acacggccgc ggccgcgacg gtgagccggc
    22621 tgccgtacgg gaggaagagc gctccgccga tcatgacgag cgtgccgagc agggcgacgg
    22681 ccggagccgt gaacgcgccc cggaggttgg gggcgacggc ggccacgccc tgggcgaggg
    22741 gcccggagtc ggcgaggtcc gcgagggcct gggcggcccg gtcggtacgg ctcgcccggc
    22801 gggtcagcga gcgcagcaga cggccggccg tggtgtagca ggcggcgagc gcgcagccga
    22861 tgagcagggc gtagaagacg atgcgcggcg tggtgagcgc ggtgaggacc gcgatcatgg
    22921 cccagcgctc gccgatcggc agcacgatca tccggcgcgc ccagaccgtc cagccgacgc
    22981 tgtcgagctt gtcggagagg gcggcggtgg ggctggtgtt ggcgaccgcg tcgtggttgg
    23041 cctcgttgaa cgagaagtcc acgacatggc ggcaggcctg gaggaccatg gcgccgagcg
    23101 ccaggaccca gacgtcatca ccgccacgga cggcgccgat ggcgagcccg gcgtagtacg
    23161 cgtactcctt ggcccggtcg aaggtggcgt ccagccaggc gcccatcgtg gagtactgga
    23221 gcgagtagcg ggcgagctgc ccgtcggtgc agtccagcac gaaggagacc agcagcagga
    23281 tcccggcggc gatgtagccg ccgcgggttc cggtggccgc cgcgcccgcc gcgacgagcg
    23341 cggtgatcag ggacgcggtg gtgacctggt tcggggtgag gccccggcgg gcgcaccagc
    23401 gggcgatgta gcgggagtac gggctgatgg cgaaggtggt gaagaagccg tcgtgggcct
    23461 tgaccgcgct gcgcagccgg accgcctcgt cgtcgaccgc gtcgcgggcg ctctcggcgg
    23521 ccgcccgcgc tgtggcgtcg gcggggacgg tggcggtgag cgatcccagc tcggggcgct
    23581 tgacggcggt gccctcggcc tccagcgcca cggcgatccg gccggggacg gtgcggtcct
    23641 cgggcgccgg gtcggtgtcg ggggcgacga cgggggcgcc cgcgccgacg gccgccgtgg
    23701 tgcgccggag cgcgcgcagc agggcgccgc gcgcctcggg ctgggcggtg agggcaccgg
    23761 gcacggtggc ggcggcgaag cgcgggtcgg tcagtccgag cctcagcgcg tggacgtggc
    23821 cgacgaaacg cggatcgacg agggcgaccc ggcggccggc cggaacggcg gcgaggaggg
    23881 ttgcggcgtc accggcgtcg gcggcggtct gcacgtcgaa gcccagggac cgcagatcgt
    23941 ccgcgagcga cgacccgggt accggcgtac cggtgaggat ggcggtcgac agacgaactc
    24001 actccttggc actgacgtgg acgacacacg gcggcacggc cacatggcgg accggcggcg
    24061 tgtcggctga ggctatcgga tgaacggaag accgagttca ccacccgttt gtgcgccgtt
    24121 cgggtggacc tgcgcggtcg ggcgccgttc gcgatcatca tcatcgatcg ggggcccggc
    24181 ccacaaaccg cggaggcggg cgggaacgcc gcgagggcct ggtccggacg acaggccttt
    24241 aggctggcgg ccatgacatg gctgatcact ggcggggcgg gttacatcgg ggcacacgtg
    24301 gcacgggcca tggtcgcggc gggcgagcgg gtcgtggtgc tcgacgaccg ctccagcggc
    24361 gtcgtcgacc ggctgccgga cgccgtcacg ctggtggagg gctccgcctc cgaccgggcg
    24421 ctgctggacc gggtgctggc cggtcacgcg gtgagcggtg tggtgcacct cgcggcgaag
    24481 aagcaggtcg gcgagtccgt ggagaagccg ctgctgtact accgggagaa cgtcgcgggg
    24541 ctggccgtcc tgctggaggc cgtggtcgcg gcgggggtgc ggcgcttcct cttctcgtcc
    24601 tcggcggccg tgtacggcgt accggacgtg gacctcatca cggaggagac gccctgcctc
    24661 cccatcaacc cgtacggcga gacgaagctc gccggtgagt ggctggtgcg ggccaccggc
    24721 aaggcgcacg ggctctcgac cgcctgtctg cggtacttca acgtggcggg agcggccgcg
    24781 ccggagctgg cggacaccgg ggtgttcaac atcgtgccga tgatgttcga gcggctgacg
    24841 ggcggcgagg ccccgcggat cttcggcgac gactacccga cgccggacgg cacctgcatc
    24901 cgcgactaca tccacgtcgc cgatctggcg gaggcgcacc tcgcggtcgc gcggcggctg
    24961 gacgagacgg gcgcgggcga tctgacgctg aacgtcggcc ggggcgaggg cgtgtcggtg
    25021 cgggagctgg cggacgtgat cggcgaggtg acggggagcg gcctgaagcc ggtggtcgag
    25081 ccgcgtcggg ccggtgacgc gccgaaggcg gtggcgtcgg ccgcgcggat caccggggag
    25141 ctgggctgga cggcccggcg gggtgtgcgc gagatggtcg agtcggcctg ggagggctgg
    25201 tgcctgcacc accccgaggc ccgtccgtga tcggtttccg ggcggtgccc ctgatcgtgt
    25261 caacgctctg acctgcgcag cgttttcgca ggtcagagca gatgacaacg gtgttcagtc
    25321 ccgtgttgcc ccataccccc cgcccgtagt tcactgggcc cgaccggggc ggttgggccc
    25381 cggcacgtcc tacggacctg gaggcgtttt ccatgggggc tggccacgat cacgggcatg
    25441 cgcacggcgg gccgcctccg acgggaacgg cggccgccgc gcaccgggga cggctccgga
    25501 tcgccctggc gatcaccctg agcgtgatgg tcatggagat cgtcggcggg gtgctctccg
    25561 actccctcgc gctgatcgcg gacgccgccc acatggccac cgatgccctg gggctcggga
    25621 tggcgctgct cgccatccac ttcgccaacc gcccggccgc gctgaaccgc accttcggct
    25681 tcgcccgcgc ggagatcctg gcggcgctcg ccaactgtct gctgctgctg ggggtcggcg
    25741 cctacctgat ctacgaggct gtggagcggt tcatcactcc ggccgagacg aagggcgggc
    25801 tggccatcgc gttcgccgcg gtcggtctgg tggccaacgt cgtctccctc tcgctgctga
    25861 tgcgcgggca gaaggagagc ctcaatgtgc ggggcgccta cctggaggtc atggccgaca
    25921 ccctgggctc gatcgcggtg atcgtctcgg cggggatcat catggcgacc ggctggcagg
    25981 ccgccgaccc gatcgcctcg ctggtgatcg gcctgatgat cgtcccccgg acggtgaagc
    26041 tgctgcggga gaccctggac gtgctgctgg aggccgcgcc caagggggtc gacatggcgg
    26101 aggtacgggc ccacatcacg gcgctgcccg gggtgctgga cgtccatgac ctgcacgcct
    26161 ggacgatcac ctcggggatg ccggtgctct ccgcccatgt ggtggtgcgc caggaaatgc
    26221 tggactcgat agggcacgag aaggtgctgc acgagttgca gggctgcctc ggggaccact
    26281 tcgacgtgga gcactgcacc ttccagttgg agccgagcgg tcacgcggag cacgaggcgc
    26341 gtctctgcca ctgagccagg ggccgggcgt gccgcactcc ggtgccg
//
