LOCUS       NZ_BMSI01000025        49385 bp    DNA     linear   CON 02-AUG-2024
DEFINITION  Streptomyces asoensis strain JCM 4185 sequence25, whole genome
            shotgun sequence.
ACCESSION   NZ_BMSI01000025
VERSION     NZ_BMSI01000025.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces asoensis
  ORGANISM  Streptomyces asoensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 49385)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014649075.1-RS_2024_08_02
            Annotation Date                   :: 08/02/2024 04:45:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,813
            CDSs (total)                      :: 7,736
            Genes (coding)                    :: 7,563
            CDSs (with protein)               :: 7,563
            Genes (RNA)                       :: 77
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 53 of 173
            Pseudo Genes (incomplete)         :: 140 of 173
            Pseudo Genes (internal stop)      :: 10 of 173
            Pseudo Genes (multiple problems)  :: 28 of 173
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:21:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 49385
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMSI01000025.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..49385
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..49385
                     /SMILES="C(C)=CC(C)C(O)C(C)=CC(C)CCC(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..49385
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[2454:29846](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2455..29846
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     gene            <1..2401
                     /locus_tag="IE189_RS37395"
     source          1..49385
                     /culture_collection="JCM:4185"
                     /db_xref="taxon:249586"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces asoensis"
                     /strain="JCM 4185"
                     /submitter_seqid="sequence25"
                     /type_material="type strain of Streptomyces cacaoi subsp.
                     asoensis"
     CDS             <3..2401
                     /NRPS_PKS="Domain: PKS_KR (346-525). E-value: 2.6e-61.
                     Score: 198.7. Matches aSDomain:
                     nrpspksdomains_IE189_RS37395_PKS_KR.1"
                     /NRPS_PKS="Domain: ACP (635-705). E-value: 4.1e-31. Score:
                     99.1. Matches aSDomain: nrpspksdomains_IE189_RS37395_ACP.1"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (723-798). E-value:
                     2.4e-06. Score: 20.3. Matches aSDomain:
                     nrpspksdomains_IE189_RS37395_PKS_Docking_Cterm.1"
                     /codon_start=2
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1047: phosphopantetheine-binding domain-containing
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF020243.4"
                     /locus_tag="IE189_RS37395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_189928430.1"
                     /sec_met_domain="adh_short (E-value: 2.6e-62, bitscore:
                     200.4, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.4e-15, bitscore:
                     48.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="GHVRGLPGVDWRAVFAGTGAARVDLPTYPFQRTRYWLDDLAASVT
                     DEDGSAADPAEAEFWDAVERGDLDGVAAELEVGTDPLGAVLPALSAWRRRRRERSQVDR
                     WRYRTVWRPLEAGSATRSSNDGALATTPVLTGRWLLLIPADLATDPWADAAERTLTGHG
                     AEVERVTIDTADTVNAADASDGGRDRFAGLLRDGTAGVLSLLALDDAPHPGHPAVPASL
                     AAHLALAQAMAGSGTTARLWAATRGGVLTGRSDPRTSPGQAQTWGLGRVVALEEPALWG
                     GLVDLPDTADDAAAARLAAVLGGLPAPDGHGQEDQLAIRPDGVHAARLVRAPLGDEPAR
                     RAWQPGGTVLITGGTGGIGSKVARWFAGNGARHLLLTGRRGPGAPGAAELRAELEQLGA
                     QVTITACDMADRDAVAALVAAVPQEHPLTAVVHAAGVPQGYTPFTDTTAGDLAEVTAGK
                     VAGAAHLDDVLADTPLDAFVLFSSNAAVWGSGGQAAYAAGNAYLDALAARRRALGRTAT
                     SLAWGAWGGGGMMAAEGAAEYMGRRGVLEMAPEPATAAMVQAVEHDETTVAVADVEWER
                     FVLGFTARRPSPLLAEIPEVRAALREDADEQDAGQDTARAALTARLAGMTGHEQLRTLM
                     ELVREEAAAVLRHDGTDGIQGGRAFKELGFDSLTAVELRNRLKAATGLRLSAAVVFDHP
                     TPAALAAHLRGLLVADGAQKETGAAMDGLKALEDSAAALAGDRDADGKARIVERLEALL
                     WKLRDNGAEAGSGPGDDADPAPDTDDLAAATAEDMFDLLDRELGTA"
     aSDomain        1043..1579
                     /ASF="KR domain putatively catalyzing L-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37395_PKS_KR.1"
                     /evalue="2.60E-61"
                     /label="IE189_RS37395_PKS_KR.1"
                     /locus_tag="IE189_RS37395"
                     /protein_end="525"
                     /protein_start="346"
                     /score="198.7"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: A1"
                     /tool="antismash"
                     /translation="GTVLITGGTGGIGSKVARWFAGNGARHLLLTGRRGPGAPGAAELR
                     AELEQLGAQVTITACDMADRDAVAALVAAVPQEHPLTAVVHAAGVPQGYTPFTDTTAGD
                     LAEVTAGKVAGAAHLDDVLADTPLDAFVLFSSNAAVWGSGGQAAYAAGNAYLDALAARR
                     RALGRTATSLAWGAWG"
     aSModule        1043..2119
                     /domains="nrpspksdomains_IE189_RS37395_PKS_KR.1"
                     /domains="nrpspksdomains_IE189_RS37395_ACP.1"
                     /incomplete
                     /locus_tags="IE189_RS37395"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       1046..1144
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37395_0001"
                     /evalue="5.30E-14"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE189_RS37395"
                     /protein_end="380"
                     /protein_start="347"
                     /score="44.7"
                     /tool="antismash"
                     /translation="TVLITGGTGGIGSKVARWFAGNGARHLLLTGRR"
     CDS_motif       1424..1534
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37395_0002"
                     /evalue="7.60E-18"
                     /label="PKSI-KR_m4"
                     /locus_tag="IE189_RS37395"
                     /protein_end="510"
                     /protein_start="473"
                     /score="57.1"
                     /tool="antismash"
                     /translation="LDAFVLFSSNAAVWGSGGQAAYAAGNAYLDALAARRR"
     aSDomain        1910..2119
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37395_ACP.1"
                     /evalue="4.10E-31"
                     /label="IE189_RS37395_ACP.1"
                     /locus_tag="IE189_RS37395"
                     /protein_end="705"
                     /protein_start="635"
                     /score="99.1"
                     /tool="antismash"
                     /translation="ELVREEAAAVLRHDGTDGIQGGRAFKELGFDSLTAVELRNRLKAA
                     TGLRLSAAVVFDHPTPAALAAHLRG"
     aSDomain        2174..2398
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37395_PKS_Docking_Cterm.
                     1"
                     /evalue="2.40E-06"
                     /label="IE189_RS37395_PKS_Docking_Cterm.1"
                     /locus_tag="IE189_RS37395"
                     /protein_end="798"
                     /protein_start="723"
                     /score="20.3"
                     /tool="antismash"
                     /translation="KALEDSAAALAGDRDADGKARIVERLEALLWKLRDNGAEAGSGPG
                     DDADPAPDTDDLAAATAEDMFDLLDRELGT"
     gene            2455..8043
                     /locus_tag="IE189_RS37400"
                     /old_locus_tag="GCM10010496_75990"
     CDS             2455..8043
                     /EC_number="2.3.1.-"
                     /EC_number="6.4.-.-"
                     /GO_component="GO:0034081 - polyketide synthase complex
                     [Evidence IEA]"
                     /GO_process="GO:0030639 - polyketide biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_Docking_Nterm (4-32). E-value:
                     4.5e-15. Score: 46.9. Matches aSDomain:
                     nrpspksdomains_IE189_RS37400_PKS_Docking_Nterm.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (36-463). E-value:
                     3.2e-178. Score: 584.9. Matches aSDomain:
                     nrpspksdomains_IE189_RS37400_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (582-881). E-value: 2.6e-105.
                     Score: 344.0. Matches aSDomain:
                     nrpspksdomains_IE189_RS37400_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (951-1117). E-value: 1.5e-53.
                     Score: 173.5. Matches aSDomain:
                     nrpspksdomains_IE189_RS37400_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (1427-1607). E-value: 4.6e-56.
                     Score: 181.6. Matches aSDomain:
                     nrpspksdomains_IE189_RS37400_PKS_KR.1"
                     /NRPS_PKS="Domain: ACP (1706-1778). E-value: 1.4e-32.
                     Score: 103.8. Matches aSDomain:
                     nrpspksdomains_IE189_RS37400_ACP.1"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (1789-1859). E-value:
                     1.4e-17. Score: 56.3. Matches aSDomain:
                     nrpspksdomains_IE189_RS37400_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1047: phosphopantetheine-binding domain-containing
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173983.1"
                     /locus_tag="IE189_RS37400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_75990"
                     /product="type I polyketide synthase"
                     /protein_id="WP_189928432.1"
                     /sec_met_domain="mod_KS (E-value: 1.9e-224, bitscore:
                     735.7, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 3.2e-93, bitscore:
                     302.4, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 9.7e-106, bitscore:
                     344.0, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1e-57, bitscore:
                     185.4, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.7e-17, bitscore:
                     53.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAENEEKLLEYLKRVTGDLRQTQRRLREAEAAHSEPVAIVGMACR
                     YPGGVDSPEDLWELVARGGDAVTGFPTDRGWDVEGQYDPDPARSGKNYVRAGGFLHGVT
                     DFDAGFFGISPREALAMDPQQRLLLEGAWELFERSGIDPTSLKGSPTGTFIGFSSADYG
                     WELPRIPESVEGYYATGNFASVMSGRIAYTFGLEGLAVTVDAACSSSLVALHLAAQALR
                     SGECSLAVAGGVTVMSTAVGYAEFSRQRALSPDGRCRAFSASADGFGPAEGLGLLLVER
                     LRDARRNGHQVLAVVRGSAVNQDGASNGLTAPNGPAQERVIRAALRNARVSPDEVDAVE
                     AHGTGTPLGDPIEAHALLSTYGERRPKERPLWLGSVKSNIGHTSAAAGVAGVIKMVQAM
                     RHGVLPKTLHADEPTPHVDWSPGTVRLLSEPRPWPDTGDRPRRAGVSAFGISGTNTHVV
                     LEQAPAANPTATEPAPAPRPLSGLTAATVPWPLSARSAPALRDQAELLSAHLSENPGTP
                     LDGVGRTLATARAALEHRAVLLAADRDEALAALAAVSGGHPDARVVHGVTLTDGTEQEL
                     AGRVVFVFPGQGSQWLGMGAGLWESSPVFRERLQECDAALSVLVDWSVTDVVRGVPDAA
                     SLDDVVVVQASLWAVMVSLAAVWRSVGVEPGAVIGHSQGEIAAAVVAGGLSVEDGARVV
                     VLRARAIARSLSGHGGMVSVATGADRVRELIAGWGERISIASVNGPSSTVVSGEPVALD
                     ELMAACESEGIRARRIAVDYASHSPQVESIREQVTDALADVEPRTAHVPFYSTVTGSVI
                     DTSGLDAGYWVTNLRQEVRFDVTVRELLADGFGYFVECSPHPVLTVGMQETFDDVADVQ
                     AVALGTLRRDEGGPERFLTSLAEGYVRGLSVDWNAVFAGTGDDEPLLDLPTYAFQRRRY
                     WLDGGAASVTDPAGLGLGDSGHPLLGATVGVADDERLLLTGLLSRRAQPWLADHAVHGR
                     ALVGGATVAELALAAAVQAGADRVETLVVEAGLPLPEGGGVQVQLSVGAPDGEGRRDLA
                     LYARPGDALPDTPWTRHARGTVAASPSTAPAGEPAGVWPPEDAVPVGTGEVYERLASAG
                     YGYGPAFQGLRALWRRGGDLFAEVALTEEQARGAGAFGLHPALLDAALHPVLLDHLDGA
                     DPAVLLPAEWHGLALHAVGATLLRVRIRPAGPGAVSLFLADAAGAPVASVAEVRLRGHS
                     PEELAGAPGALRDALFRLEWAPFDRPLSAAAPVGGWTVVGPDELGIGSDAERDAEPGLA
                     LASFAAFPAADPAAALAPRVHEAAAEALGLVQKWLVDQRSESVPLVLVTSEAVAAAPGD
                     RITDLVHAPLWGLVRSAQAEYPPGRFLLVDVDDHEGSRTALAAAAAAALEAGEPQLAVR
                     NGTVLVPRLVRAGTVEGAAAPFPESGTVLITGGTGTSGALVARHLVAAHGARHLLLVSR
                     RGPDAPGAGALAEELRGLGADTVDVVACDAADRDALADVVDSVPGNRPLTAVVHAAGVL
                     DDALTASLTAPQMGRVLRPKADAALVLHELTRDRELSAFVLFSSAAGTLGNAGQANLAA
                     ANAFLDALAARRRALGLPAVSLAWGPWALGEDDGRAAGGGVRPFSPEEGLGLLDAALAD
                     GAALTVPVRLDLPALEAAAASGTLPAPLRRLVRVPARRAAAAGPGTAAGTGLARGLAVV
                     PEAERRRILLDLVRTEVAAVLRHATVDDVEADRAFKELGFDSLTAVELRNRLGAATGLR
                     LPPTLVFTYPTPAALVRFLLDEIAPGTGEDSATPVLADLERLDASLSGLAADAVTRDRI
                     TRRLEALLWKWSGEPDGEEGVLDRGDLDAASDDEMFALIDQELGGAG"
     aSDomain        2467..2550
                     /aSDomain="PKS_Docking_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37400_PKS_Docking_Nterm.
                     1"
                     /evalue="4.50E-15"
                     /label="IE189_RS37400_PKS_Docking_Nterm.1"
                     /locus_tag="IE189_RS37400"
                     /protein_end="32"
                     /protein_start="4"
                     /score="46.9"
                     /tool="antismash"
                     /translation="EEKLLEYLKRVTGDLRQTQRRLREAEAA"
     aSDomain        2563..3843
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37400_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="3.20E-178"
                     /label="IE189_RS37400_PKS_KS.1"
                     /locus_tag="IE189_RS37400"
                     /protein_end="463"
                     /protein_start="36"
                     /score="584.9"
                     /tool="antismash"
                     /translation="VAIVGMACRYPGGVDSPEDLWELVARGGDAVTGFPTDRGWDVEGQ
                     YDPDPARSGKNYVRAGGFLHGVTDFDAGFFGISPREALAMDPQQRLLLEGAWELFERSG
                     IDPTSLKGSPTGTFIGFSSADYGWELPRIPESVEGYYATGNFASVMSGRIAYTFGLEGL
                     AVTVDAACSSSLVALHLAAQALRSGECSLAVAGGVTVMSTAVGYAEFSRQRALSPDGRC
                     RAFSASADGFGPAEGLGLLLVERLRDARRNGHQVLAVVRGSAVNQDGASNGLTAPNGPA
                     QERVIRAALRNARVSPDEVDAVEAHGTGTPLGDPIEAHALLSTYGERRPKERPLWLGSV
                     KSNIGHTSAAAGVAGVIKMVQAMRHGVLPKTLHADEPTPHVDWSPGTVRLLSEPRPWPD
                     TGDRPRRAGVSAFGISGTNTHVVLEQAP"
     aSModule        2563..7788
                     /complete
                     /domains="nrpspksdomains_IE189_RS37400_PKS_KS.1"
                     /domains="nrpspksdomains_IE189_RS37400_PKS_AT.1"
                     /domains="nrpspksdomains_IE189_RS37400_PKS_DH.1"
                     /domains="nrpspksdomains_IE189_RS37400_PKS_KR.1"
                     /domains="nrpspksdomains_IE189_RS37400_ACP.1"
                     /locus_tags="IE189_RS37400"
                     /monomer_pairings="mmal -> Me-ccmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       3049..3093
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37400_0001"
                     /evalue="1.30E-04"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE189_RS37400"
                     /protein_end="213"
                     /protein_start="198"
                     /score="14.3"
                     /tool="antismash"
                     /translation="LAVTVDAACSSSLVA"
     CDS_motif       3235..3273
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37400_0002"
                     /evalue="4.20E-02"
                     /label="PKSI-KS_m4"
                     /locus_tag="IE189_RS37400"
                     /protein_end="273"
                     /protein_start="260"
                     /score="7.5"
                     /tool="antismash"
                     /translation="FSASADGFGPAEG"
     CDS_motif       3469..3513
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37400_0003"
                     /evalue="5.40E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE189_RS37400"
                     /protein_end="353"
                     /protein_start="338"
                     /score="12.3"
                     /tool="antismash"
                     /translation="VEAHGTGTPLGDPIE"
     CDS_motif       3574..3618
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37400_0004"
                     /evalue="1.50E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="IE189_RS37400"
                     /protein_end="388"
                     /protein_start="373"
                     /score="11.1"
                     /tool="antismash"
                     /translation="GSVKSNIGHTSAAAG"
     CDS_motif       4195..4248
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37400_0005"
                     /evalue="6.00E-08"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="IE189_RS37400"
                     /protein_end="598"
                     /protein_start="580"
                     /score="24.6"
                     /tool="antismash"
                     /translation="VFVFPGQGSQWLGMGAGL"
     aSDomain        4201..5097
                     /ASF="Methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37400_PKS_AT.1"
                     /evalue="2.60E-105"
                     /label="IE189_RS37400_PKS_AT.1"
                     /locus_tag="IE189_RS37400"
                     /protein_end="881"
                     /protein_start="582"
                     /score="344.0"
                     /specificity="substrate consensus: mmal"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFPGQGSQWLGMGAGLWESSPVFRERLQECDAALSVLVDWSVTDV
                     VRGVPDAASLDDVVVVQASLWAVMVSLAAVWRSVGVEPGAVIGHSQGEIAAAVVAGGLS
                     VEDGARVVVLRARAIARSLSGHGGMVSVATGADRVRELIAGWGERISIASVNGPSSTVV
                     SGEPVALDELMAACESEGIRARRIAVDYASHSPQVESIREQVTDALADVEPRTAHVPFY
                     STVTGSVIDTSGLDAGYWVTNLRQEVRFDVTVRELLADGFGYFVECSPHPVLTVGMQET
                     FDDVADVQAVALGTLRRD"
     CDS_motif       4363..4434
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37400_0006"
                     /evalue="4.30E-06"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="IE189_RS37400"
                     /protein_end="660"
                     /protein_start="636"
                     /score="19.6"
                     /tool="antismash"
                     /translation="LDDVVVVQASLWAVMVSLAAVWRS"
     CDS_motif       4438..4548
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37400_0007"
                     /evalue="8.00E-16"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="IE189_RS37400"
                     /protein_end="698"
                     /protein_start="661"
                     /score="50.0"
                     /tool="antismash"
                     /translation="GVEPGAVIGHSQGEIAAAVVAGGLSVEDGARVVVLRA"
     CDS_motif       4657..4695
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37400_0008"
                     /evalue="2.50E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="IE189_RS37400"
                     /protein_end="747"
                     /protein_start="734"
                     /score="11.2"
                     /tool="antismash"
                     /translation="ASVNGPSSTVVSG"
     CDS_motif       4765..4797
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37400_0009"
                     /evalue="2.50E-04"
                     /label="PKSI-AT-mM_m6"
                     /locus_tag="IE189_RS37400"
                     /protein_end="781"
                     /protein_start="770"
                     /score="13.7"
                     /tool="antismash"
                     /translation="VDYASHSPQVE"
     CDS_motif       4903..4950
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37400_0010"
                     /evalue="6.40E-05"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="IE189_RS37400"
                     /protein_end="832"
                     /protein_start="816"
                     /score="15.2"
                     /tool="antismash"
                     /translation="LDAGYWVTNLRQEVRF"
     CDS_motif       4993..5022
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37400_0011"
                     /evalue="3.30E-03"
                     /label="PKSI-AT-mM_m9"
                     /locus_tag="IE189_RS37400"
                     /protein_end="856"
                     /protein_start="846"
                     /score="10.1"
                     /tool="antismash"
                     /translation="FVECSPHPVL"
     CDS_motif       5131..5151
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37400_0012"
                     /evalue="1.80E+01"
                     /label="PKSI-KS_m4"
                     /locus_tag="IE189_RS37400"
                     /protein_end="899"
                     /protein_start="892"
                     /score="-0.2"
                     /tool="antismash"
                     /translation="AEGYVRG"
     aSDomain        5308..5805
                     /ASF="catalytic triad H,G,P found: False"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37400_PKS_DH.1"
                     /evalue="1.50E-53"
                     /label="IE189_RS37400_PKS_DH.1"
                     /locus_tag="IE189_RS37400"
                     /protein_end="1117"
                     /protein_start="951"
                     /score="173.5"
                     /tool="antismash"
                     /translation="HPLLGATVGVADDERLLLTGLLSRRAQPWLADHAVHGRALVGGAT
                     VAELALAAAVQAGADRVETLVVEAGLPLPEGGGVQVQLSVGAPDGEGRRDLALYARPGD
                     ALPDTPWTRHARGTVAASPSTAPAGEPAGVWPPEDAVPVGTGEVYERLASAGYGYGPAF
                     QGL"
     CDS_motif       5392..5469
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37400_0013"
                     /evalue="2.20E-06"
                     /label="PKSI-DH_m2"
                     /locus_tag="IE189_RS37400"
                     /protein_end="1005"
                     /protein_start="979"
                     /score="20.2"
                     /tool="antismash"
                     /translation="WLADHAVHGRALVGGATVAELALAAA"
     aSDomain        6736..7275
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37400_PKS_KR.1"
                     /evalue="4.60E-56"
                     /label="IE189_RS37400_PKS_KR.1"
                     /locus_tag="IE189_RS37400"
                     /protein_end="1607"
                     /protein_start="1427"
                     /score="181.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="GTVLITGGTGTSGALVARHLVAAHGARHLLLVSRRGPDAPGAGAL
                     AEELRGLGADTVDVVACDAADRDALADVVDSVPGNRPLTAVVHAAGVLDDALTASLTAP
                     QMGRVLRPKADAALVLHELTRDRELSAFVLFSSAAGTLGNAGQANLAAANAFLDALAAR
                     RRALGLPAVSLAWGPWA"
     CDS_motif       6739..6840
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37400_0014"
                     /evalue="2.90E-08"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE189_RS37400"
                     /protein_end="1462"
                     /protein_start="1428"
                     /score="26.3"
                     /tool="antismash"
                     /translation="TVLITGGTGTSGALVARHLVAAHGARHLLLVSRR"
     CDS_motif       7126..7230
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37400_0015"
                     /evalue="1.10E-16"
                     /label="PKSI-KR_m4"
                     /locus_tag="IE189_RS37400"
                     /protein_end="1592"
                     /protein_start="1557"
                     /score="53.3"
                     /tool="antismash"
                     /translation="AFVLFSSAAGTLGNAGQANLAAANAFLDALAARRR"
     aSDomain        7573..7788
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37400_ACP.1"
                     /evalue="1.40E-32"
                     /label="IE189_RS37400_ACP.1"
                     /locus_tag="IE189_RS37400"
                     /protein_end="1778"
                     /protein_start="1706"
                     /score="103.8"
                     /tool="antismash"
                     /translation="LDLVRTEVAAVLRHATVDDVEADRAFKELGFDSLTAVELRNRLGA
                     ATGLRLPPTLVFTYPTPAALVRFLLDE"
     aSDomain        7822..8031
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37400_PKS_Docking_Cterm.
                     1"
                     /evalue="1.40E-17"
                     /label="IE189_RS37400_PKS_Docking_Cterm.1"
                     /locus_tag="IE189_RS37400"
                     /protein_end="1859"
                     /protein_start="1789"
                     /score="56.3"
                     /tool="antismash"
                     /translation="PVLADLERLDASLSGLAADAVTRDRITRRLEALLWKWSGEPDGEE
                     GVLDRGDLDAASDDEMFALIDQELG"
     gene            8134..13185
                     /locus_tag="IE189_RS37405"
                     /old_locus_tag="GCM10010496_76000"
     CDS             8134..13185
                     /NRPS_PKS="Domain: PKS_Docking_Nterm (18-46). E-value:
                     2.6e-15. Score: 47.6. Matches aSDomain:
                     nrpspksdomains_IE189_RS37405_PKS_Docking_Nterm.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (50-477). E-value:
                     2.4e-177. Score: 582.0. Matches aSDomain:
                     nrpspksdomains_IE189_RS37405_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (586-885). E-value: 7.3e-106.
                     Score: 345.8. Matches aSDomain:
                     nrpspksdomains_IE189_RS37405_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_KR (1234-1412). E-value: 2.3e-62.
                     Score: 202.1. Matches aSDomain:
                     nrpspksdomains_IE189_RS37405_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1510-1600). E-value: 2.1e-30.
                     Score: 96.9. Matches aSDomain:
                     nrpspksdomains_IE189_RS37405_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (1612-1682). E-value:
                     3.6e-17. Score: 55.0. Matches aSDomain:
                     nrpspksdomains_IE189_RS37405_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173984.1"
                     /locus_tag="IE189_RS37405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_76000"
                     /product="type I polyketide synthase"
                     /protein_id="WP_189928434.1"
                     /sec_met_domain="mod_KS (E-value: 1.1e-227, bitscore:
                     746.4, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 5.3e-92, bitscore:
                     298.4, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 2.7e-106, bitscore:
                     345.8, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.4e-63, bitscore:
                     204.6, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 6.6e-10,
                     bitscore: 29.0, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.2e-15, bitscore:
                     47.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNGSKDGSRGGSGDGGTEAKLRDYLKRVTAELGQARHRLREAEA
                     AAGQPIAIIGMACRYPGGCDSPERLWELVDSGRDAITPFPADRGWDLDALYHPDPDHRG
                     TSYVREGGFLHDAADFDAAFFGITPREALGMDPQQRLLLETSWEACERAGIDPLTLKGA
                     QVGVYTGIVNSGYVSRLRETPESVEGYVVTGTMASVASGRIAYTLGLEGPAVSIETACS
                     SSLVALHLAVQALRDGECSMALAGGVAVMPVPDAFVEFSRQRGMAPDGRIKAFAAAADG
                     TTWSEGAGVLLVERLADARRNGHPVLAVVRGSAINQDGASNGLSAPNDLAQERVIRAAL
                     ANARLTPADVDAVEAHGTGTTLGDPIEAQALLAAYGRERPQDRPLWLGSIKSNLGHSGP
                     AAGVAGVIKMVEAMRHGVLPRTLHVDAPTPHVDWSSGAVRLLTEPVPWTGHDDRPRRAG
                     VSAFGISGTNAHVILEEAPEAGPGERRPSGEPHLVADVLPWVVSGRSDAALRAQAGRLA
                     GFVEQRSELTVGDVARSLVETRSALEHRAVVLAGDRDAAVGALRSVAEGVPVPGVVAGV
                     VSGEQGRVVFVFPGQGSQWLGMGAGLWESSPVFRERLQECDAALSALVDWSVTDVVRGV
                     PDAASLDDVVVVQASLWAVMVSLAAMWRSVGVEPGAVIGHSQGEIAAAVVAGGLSVEDG
                     ARVVVLRARAIGQSLSGHGGMVSLAAGADRVRELIAAWGERISIASVNGPSSTVVSGEP
                     DALDDLMAACDGEGIRARRIAVDYASHSAQVESIREQVTEALEDIEPRAAEVPFYSTVL
                     GSVIDTGDLDAGYWVTNLRQEVRFDATVRELLADGFGYFVECSPHPVLTVGMQETFEDH
                     ADSQAVALGTLRRDEGGPERLLTSLAEGYVRGLAVDWHTLFAGTGAQRIELPTYAFRRR
                     RYWLEEPAGAAPKQDAGELDEVDAGFWAAVDAGALETLTTELGVPADEPFSALLPALSS
                     WRGRRREESRADGWRYRVVWRPARFPADRQPRGHWLVVVPEGRADDPWAAGSVRALERA
                     GAGVTRLVVDAVGADRDRLAHVLREAFTEGSGAGSGETPPGGVLSLLALDDAPHPAYPA
                     VPSGLAATVTLVQAMVQAGEGMPAPPRLWCATRGAVSTGASDPLASPAQAHAWGLGRVA
                     ALEHPLLWGGLVDLPADAGDTEVARLAAVLRAPAEEDHLAVRGDGVHVRRLVRAPAEAV
                     PAVREWRPRGSVLVTGGTGGIGGHLARRLAQTGAEHLVLVSRSGPEAPGATELAEELTA
                     AGAKVSLVACDVADRDALAAVLASVPADQPLTAVVHAAAVLDDGVIESLDPERMERVLR
                     VKAQGALHLDELTRDADLSAFVLCSSFGATFGLPALGNYAPGNAFLDALAERRRAQGLP
                     ATSVAWGTWAGTGMAAGDVGARGRLEGIHEMDPEPASAALGRILDRDETTAVLIDLRWE
                     RFAPVFHAKRPTALFSEIPEAVRALARGAGDGDADPATADEAADGLRARLAGVPRAEQE
                     RELLELVRSHAGVVMGHVTLTGNARDAVAPDRPFRDLGFDSLMAVELRNRVGAATGVAL
                     PATLVFDHPTPEAVARHLRQEMGLGDADGIPPGFPELERLEAALAAAPADDEARARLAK
                     RLERLLWTVSGDDLATTPGEGSGDREFSTVSNDEMFDLIDRELGA"
     aSDomain        8188..8271
                     /aSDomain="PKS_Docking_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37405_PKS_Docking_Nterm.
                     1"
                     /evalue="2.60E-15"
                     /label="IE189_RS37405_PKS_Docking_Nterm.1"
                     /locus_tag="IE189_RS37405"
                     /protein_end="46"
                     /protein_start="18"
                     /score="47.6"
                     /tool="antismash"
                     /translation="EAKLRDYLKRVTAELGQARHRLREAEAA"
     aSDomain        8284..9564
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37405_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="2.40E-177"
                     /label="IE189_RS37405_PKS_KS.1"
                     /locus_tag="IE189_RS37405"
                     /protein_end="477"
                     /protein_start="50"
                     /score="582.0"
                     /tool="antismash"
                     /translation="IAIIGMACRYPGGCDSPERLWELVDSGRDAITPFPADRGWDLDAL
                     YHPDPDHRGTSYVREGGFLHDAADFDAAFFGITPREALGMDPQQRLLLETSWEACERAG
                     IDPLTLKGAQVGVYTGIVNSGYVSRLRETPESVEGYVVTGTMASVASGRIAYTLGLEGP
                     AVSIETACSSSLVALHLAVQALRDGECSMALAGGVAVMPVPDAFVEFSRQRGMAPDGRI
                     KAFAAAADGTTWSEGAGVLLVERLADARRNGHPVLAVVRGSAINQDGASNGLSAPNDLA
                     QERVIRAALANARLTPADVDAVEAHGTGTTLGDPIEAQALLAAYGRERPQDRPLWLGSI
                     KSNLGHSGPAAGVAGVIKMVEAMRHGVLPRTLHVDAPTPHVDWSSGAVRLLTEPVPWTG
                     HDDRPRRAGVSAFGISGTNAHVILEEAP"
     aSModule        8284..12933
                     /complete
                     /domains="nrpspksdomains_IE189_RS37405_PKS_KS.1"
                     /domains="nrpspksdomains_IE189_RS37405_PKS_AT.1"
                     /domains="nrpspksdomains_IE189_RS37405_PKS_KR.1"
                     /domains="nrpspksdomains_IE189_RS37405_PKS_PP.1"
                     /locus_tags="IE189_RS37405"
                     /monomer_pairings="mmal -> Me-ohmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       8767..8814
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37405_0001"
                     /evalue="9.20E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE189_RS37405"
                     /protein_end="227"
                     /protein_start="211"
                     /score="17.8"
                     /tool="antismash"
                     /translation="GPAVSIETACSSSLVA"
     CDS_motif       9190..9234
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37405_0002"
                     /evalue="4.50E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE189_RS37405"
                     /protein_end="367"
                     /protein_start="352"
                     /score="12.5"
                     /tool="antismash"
                     /translation="VEAHGTGTTLGDPIE"
     CDS_motif       9886..9939
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37405_0003"
                     /evalue="5.40E-08"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="IE189_RS37405"
                     /protein_end="602"
                     /protein_start="584"
                     /score="24.8"
                     /tool="antismash"
                     /translation="VFVFPGQGSQWLGMGAGL"
     aSDomain        9892..10788
                     /ASF="Methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37405_PKS_AT.1"
                     /evalue="7.30E-106"
                     /label="IE189_RS37405_PKS_AT.1"
                     /locus_tag="IE189_RS37405"
                     /protein_end="885"
                     /protein_start="586"
                     /score="345.8"
                     /specificity="substrate consensus: mmal"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFPGQGSQWLGMGAGLWESSPVFRERLQECDAALSALVDWSVTDV
                     VRGVPDAASLDDVVVVQASLWAVMVSLAAMWRSVGVEPGAVIGHSQGEIAAAVVAGGLS
                     VEDGARVVVLRARAIGQSLSGHGGMVSLAAGADRVRELIAAWGERISIASVNGPSSTVV
                     SGEPDALDDLMAACDGEGIRARRIAVDYASHSAQVESIREQVTEALEDIEPRAAEVPFY
                     STVLGSVIDTGDLDAGYWVTNLRQEVRFDATVRELLADGFGYFVECSPHPVLTVGMQET
                     FEDHADSQAVALGTLRRD"
     CDS_motif       10054..10125
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37405_0004"
                     /evalue="2.10E-06"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="IE189_RS37405"
                     /protein_end="664"
                     /protein_start="640"
                     /score="20.5"
                     /tool="antismash"
                     /translation="LDDVVVVQASLWAVMVSLAAMWRS"
     CDS_motif       10129..10239
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37405_0005"
                     /evalue="7.10E-16"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="IE189_RS37405"
                     /protein_end="702"
                     /protein_start="665"
                     /score="50.2"
                     /tool="antismash"
                     /translation="GVEPGAVIGHSQGEIAAAVVAGGLSVEDGARVVVLRA"
     CDS_motif       10348..10386
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37405_0006"
                     /evalue="2.20E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="IE189_RS37405"
                     /protein_end="751"
                     /protein_start="738"
                     /score="11.4"
                     /tool="antismash"
                     /translation="ASVNGPSSTVVSG"
     CDS_motif       10456..10488
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37405_0007"
                     /evalue="4.30E-04"
                     /label="PKSI-AT-mM_m6"
                     /locus_tag="IE189_RS37405"
                     /protein_end="785"
                     /protein_start="774"
                     /score="13.0"
                     /tool="antismash"
                     /translation="VDYASHSAQVE"
     CDS_motif       10594..10641
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37405_0008"
                     /evalue="5.60E-05"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="IE189_RS37405"
                     /protein_end="836"
                     /protein_start="820"
                     /score="15.3"
                     /tool="antismash"
                     /translation="LDAGYWVTNLRQEVRF"
     CDS_motif       10684..10713
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37405_0009"
                     /evalue="2.90E-03"
                     /label="PKSI-AT-mM_m9"
                     /locus_tag="IE189_RS37405"
                     /protein_end="860"
                     /protein_start="850"
                     /score="10.3"
                     /tool="antismash"
                     /translation="FVECSPHPVL"
     misc_feature    10807..10809
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS_motif       10864..10896
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37405_0010"
                     /evalue="3.10E+01"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="IE189_RS37405"
                     /protein_end="921"
                     /protein_start="910"
                     /score="-1.6"
                     /tool="antismash"
                     /translation="LFAGTGAQRIE"
     aSDomain        11836..12369
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37405_PKS_KR.1"
                     /evalue="2.30E-62"
                     /label="IE189_RS37405_PKS_KR.1"
                     /locus_tag="IE189_RS37405"
                     /protein_end="1412"
                     /protein_start="1234"
                     /score="202.1"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B2"
                     /tool="antismash"
                     /translation="GSVLVTGGTGGIGGHLARRLAQTGAEHLVLVSRSGPEAPGATELA
                     EELTAAGAKVSLVACDVADRDALAAVLASVPADQPLTAVVHAAAVLDDGVIESLDPERM
                     ERVLRVKAQGALHLDELTRDADLSAFVLCSSFGATFGLPALGNYAPGNAFLDALAERRR
                     AQGLPATSVAWGTWA"
     CDS_motif       11839..11937
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37405_0011"
                     /evalue="1.00E-13"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE189_RS37405"
                     /protein_end="1268"
                     /protein_start="1235"
                     /score="43.8"
                     /tool="antismash"
                     /translation="SVLVTGGTGGIGGHLARRLAQTGAEHLVLVSRS"
     CDS_motif       12220..12324
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37405_0012"
                     /evalue="1.70E-14"
                     /label="PKSI-KR_m4"
                     /locus_tag="IE189_RS37405"
                     /protein_end="1397"
                     /protein_start="1362"
                     /score="46.3"
                     /tool="antismash"
                     /translation="AFVLCSSFGATFGLPALGNYAPGNAFLDALAERRR"
     aSDomain        12664..12933
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37405_PKS_PP.1"
                     /evalue="2.10E-30"
                     /label="IE189_RS37405_PKS_PP.1"
                     /locus_tag="IE189_RS37405"
                     /protein_end="1600"
                     /protein_start="1510"
                     /score="96.9"
                     /tool="antismash"
                     /translation="LAGVPRAEQERELLELVRSHAGVVMGHVTLTGNARDAVAPDRPFR
                     DLGFDSLMAVELRNRVGAATGVALPATLVFDHPTPEAVARHLRQE"
     aSDomain        12970..13179
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37405_PKS_Docking_Cterm.
                     1"
                     /evalue="3.60E-17"
                     /label="IE189_RS37405_PKS_Docking_Cterm.1"
                     /locus_tag="IE189_RS37405"
                     /protein_end="1682"
                     /protein_start="1612"
                     /score="55.0"
                     /tool="antismash"
                     /translation="FPELERLEAALAAAPADDEARARLAKRLERLLWTVSGDDLATTPG
                     EGSGDREFSTVSNDEMFDLIDRELG"
     gene            13191..18842
                     /locus_tag="IE189_RS37410"
                     /old_locus_tag="GCM10010496_76010"
     CDS             13191..18842
                     /EC_number="2.3.1.-"
                     /EC_number="6.4.-.-"
                     /NRPS_PKS="Domain: PKS_Docking_Nterm (4-32). E-value:
                     1.7e-12. Score: 38.7. Matches aSDomain:
                     nrpspksdomains_IE189_RS37410_PKS_Docking_Nterm.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (36-461). E-value:
                     1.1e-174. Score: 573.3. Matches aSDomain:
                     nrpspksdomains_IE189_RS37410_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (583-882). E-value: 8.5e-105.
                     Score: 342.3. Matches aSDomain:
                     nrpspksdomains_IE189_RS37410_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (951-1124). E-value: 8.9e-57.
                     Score: 184.0. Matches aSDomain:
                     nrpspksdomains_IE189_RS37410_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (1445-1624). E-value: 8e-58.
                     Score: 187.3. Matches aSDomain:
                     nrpspksdomains_IE189_RS37410_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1717-1801). E-value: 9e-30.
                     Score: 94.9. Matches aSDomain:
                     nrpspksdomains_IE189_RS37410_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (1812-1881). E-value:
                     1.3e-16. Score: 53.1. Matches aSDomain:
                     nrpspksdomains_IE189_RS37410_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173985.1"
                     /locus_tag="IE189_RS37410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_76010"
                     /product="type I polyketide synthase"
                     /protein_id="WP_189928436.1"
                     /sec_met_domain="mod_KS (E-value: 6.8e-220, bitscore:
                     720.7, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 2.2e-86, bitscore:
                     280.0, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 3.1e-105, bitscore:
                     342.3, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 5.6e-61, bitscore:
                     196.1, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.6e-07,
                     bitscore: 21.2, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2e-15, bitscore:
                     47.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTDEQKLREYLNKVMTDLRRTQRRLRSVEERDHEPVAVVGMACR
                     YPGGTESPEDLWRLVEGGGDAISGFPTDRGWDLASLRLTDPEGRELAPEGGFVAGAAAF
                     DAGLFGISPREALAMDPQQRLVLECSYEAFERAGIDPFSLKGSDTGVFVGASYTGYGAD
                     VERIPDGLEGYTMTGSANSVVSGRVAYTFGLEGPAVTIDTACSSSLVALHWAVQSLRAG
                     ETSLALAGGAMVMPSPMEFVEFSRQRILAADARCKAFAEAADGTGFSEGAGLVLLERLS
                     DARRHGHRVLAVVRGSAVNQDGASNGLTAPNGPSQRRVIEAALANARLAPADVDAVEAH
                     GTGTTLGDPIEAQALLAVYGKERPAEHPLWLGSVKSNIGHTQAAAGIAGVIKTVEALRH
                     RSLPRTLHVDAPTPQVDWSPGTVRLLTEARPWDTPGGRARRAAVSAFGISGTNAHVILE
                     EAPEDTGTPGTDGTGATGVGATTTGEHPVGLVGDVVPWPLSGRTTAALHAQAARLSAYL
                     DDHPGTSPLDVGATLALSRGALDHRAVLLATDAGSIHTALTALGEGVPTADVVPGTVLS
                     GAPRVVFVFPGQGSQWLGMGAGLWESSPVFRERLQECDAALSSLVDWSVTEVVRGLPTA
                     ASLDDVVVVQASLWAVMVSLAAVWRSVGIEPGAVIGHSQGEIAAAVVAGALSVQDGARV
                     VVLRARAIARSLSGHGGMVSVAAGADRVRELIAGWGERISIASVNGPSSTVVSGEPVAL
                     DDLMAACDGEGIRARRIAVDYASHSAQVELIREQVIEALADIEPRAAEVPFYSTVLGSV
                     IDTGDLDAGYWVTNLRQEVRFDATVRELLADGFGYFVECSPHPVLTVGMQETFDDVADA
                     QAVALGTLRRDEGGPERFLTSLAEGYVRGLAVDWHTLFAGTGADRRLDLPSYAFQRQRY
                     WLESGPAGAGDPAGLGLADAGHPLLGAAVEVAGGDQLLLTGRLSLHAHPWLADHAVQGT
                     PVLTGAAFAELALHAGERAGAEVVESLTVEAPLVVPESGGVQVQLSVGAPDEDGARELG
                     VHARPGTQEDGTPWVRYATARLVPDGARRTGAADDAGTVERLAQWPPPGAQPVSVANFH
                     QRAADAGQGYGPAFRGLRAVWRQGREMYAEVALPGDQERQAAGYGIHPALLDAALQPAR
                     LEERSGVLWTDWSGVSLRAMGATELRVHVRPSDDGAVTVTLGDASGRPVGTVEAVAARA
                     VAPEELRRGADGVRDALYRVEWTPVPAPGQTADWVVLGDDPLGVTDVLEEAGAYPQTYD
                     DLDALAGAVDAGLPLPELTVVSHGGVAPAKDGAVARHALEAVTGLLAVVQRWLADERFA
                     GARLLVVTRGAVAAGPGDGAVDLAHAAAWGLLRSATAAHPGRFGLLDLDGDDGSLAVLP
                     DAVPAVVASGEPETALRAGVVLVPRIRPAATAPAAARAVWDPDGTVLITGGTGALGRVL
                     ARHLVKQHGVRHLLLVSRRGRDADGAEALERELSSLGATVSVEACDAADREALARVLAA
                     VPADRPLTAVLHAAGALADRPLEALTAQDVEHVFTPKVTAAANLHELTRESDLAAFVLF
                     SSASGVLGSLAQPNYAAANAFLDALAAHRRAAGLAGLSLAWGLWAGASEMAGGADTDRF
                     ARAGILALSPDEGTALFDAASATDEALLVPVLLDTAALRSRAADGTLSGMLRGLVKAAP
                     GKRAASAPGTGPQEPDWAARLAGLTRDEQLHRLVELTRAHVASVLGHGTPEAIEPDRPF
                     KEIGFDSLTALELRNRLGAATGLTLPATLVFDHPTLNATAALLLDLLAPAATTAPPPAL
                     AELDRLEEALAAVPDDDTATRARVRERLQALLAGWNGAPRPSDGGDEELDDATDSELFA
                     LLDDELDTP"
     aSDomain        13203..13286
                     /aSDomain="PKS_Docking_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37410_PKS_Docking_Nterm.
                     1"
                     /evalue="1.70E-12"
                     /label="IE189_RS37410_PKS_Docking_Nterm.1"
                     /locus_tag="IE189_RS37410"
                     /protein_end="32"
                     /protein_start="4"
                     /score="38.7"
                     /tool="antismash"
                     /translation="EQKLREYLNKVMTDLRRTQRRLRSVEER"
     aSDomain        13299..14573
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37410_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="1.10E-174"
                     /label="IE189_RS37410_PKS_KS.1"
                     /locus_tag="IE189_RS37410"
                     /protein_end="461"
                     /protein_start="36"
                     /score="573.3"
                     /tool="antismash"
                     /translation="VAVVGMACRYPGGTESPEDLWRLVEGGGDAISGFPTDRGWDLASL
                     RLTDPEGRELAPEGGFVAGAAAFDAGLFGISPREALAMDPQQRLVLECSYEAFERAGID
                     PFSLKGSDTGVFVGASYTGYGADVERIPDGLEGYTMTGSANSVVSGRVAYTFGLEGPAV
                     TIDTACSSSLVALHWAVQSLRAGETSLALAGGAMVMPSPMEFVEFSRQRILAADARCKA
                     FAEAADGTGFSEGAGLVLLERLSDARRHGHRVLAVVRGSAVNQDGASNGLTAPNGPSQR
                     RVIEAALANARLAPADVDAVEAHGTGTTLGDPIEAQALLAVYGKERPAEHPLWLGSVKS
                     NIGHTQAAAGIAGVIKTVEALRHRSLPRTLHVDAPTPQVDWSPGTVRLLTEARPWDTPG
                     GRARRAAVSAFGISGTNAHVILEEAP"
     aSModule        13299..18593
                     /complete
                     /domains="nrpspksdomains_IE189_RS37410_PKS_KS.1"
                     /domains="nrpspksdomains_IE189_RS37410_PKS_AT.1"
                     /domains="nrpspksdomains_IE189_RS37410_PKS_DH.1"
                     /domains="nrpspksdomains_IE189_RS37410_PKS_KR.1"
                     /domains="nrpspksdomains_IE189_RS37410_PKS_PP.1"
                     /locus_tags="IE189_RS37410"
                     /monomer_pairings="mmal -> Me-ccmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       13722..13748
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37410_0001"
                     /evalue="3.90E+01"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="IE189_RS37410"
                     /protein_end="186"
                     /protein_start="177"
                     /score="-1.6"
                     /tool="antismash"
                     /translation="GSANSVVSG"
     CDS_motif       13776..13823
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37410_0002"
                     /evalue="1.00E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE189_RS37410"
                     /protein_end="211"
                     /protein_start="195"
                     /score="20.6"
                     /tool="antismash"
                     /translation="GPAVTIDTACSSSLVA"
     CDS_motif       14199..14243
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37410_0003"
                     /evalue="5.20E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE189_RS37410"
                     /protein_end="351"
                     /protein_start="336"
                     /score="12.3"
                     /tool="antismash"
                     /translation="VEAHGTGTTLGDPIE"
     CDS_motif       14304..14348
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37410_0004"
                     /evalue="7.30E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="IE189_RS37410"
                     /protein_end="386"
                     /protein_start="371"
                     /score="12.0"
                     /tool="antismash"
                     /translation="GSVKSNIGHTQAAAG"
     CDS_motif       14934..14987
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37410_0005"
                     /evalue="6.10E-08"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="IE189_RS37410"
                     /protein_end="599"
                     /protein_start="581"
                     /score="24.6"
                     /tool="antismash"
                     /translation="VFVFPGQGSQWLGMGAGL"
     aSDomain        14940..15836
                     /ASF="Methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37410_PKS_AT.1"
                     /evalue="8.50E-105"
                     /label="IE189_RS37410_PKS_AT.1"
                     /locus_tag="IE189_RS37410"
                     /protein_end="882"
                     /protein_start="583"
                     /score="342.3"
                     /specificity="substrate consensus: mmal"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFPGQGSQWLGMGAGLWESSPVFRERLQECDAALSSLVDWSVTEV
                     VRGLPTAASLDDVVVVQASLWAVMVSLAAVWRSVGIEPGAVIGHSQGEIAAAVVAGALS
                     VQDGARVVVLRARAIARSLSGHGGMVSVAAGADRVRELIAGWGERISIASVNGPSSTVV
                     SGEPVALDDLMAACDGEGIRARRIAVDYASHSAQVELIREQVIEALADIEPRAAEVPFY
                     STVLGSVIDTGDLDAGYWVTNLRQEVRFDATVRELLADGFGYFVECSPHPVLTVGMQET
                     FDDVADAQAVALGTLRRD"
     CDS_motif       15102..15173
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37410_0006"
                     /evalue="4.40E-06"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="IE189_RS37410"
                     /protein_end="661"
                     /protein_start="637"
                     /score="19.5"
                     /tool="antismash"
                     /translation="LDDVVVVQASLWAVMVSLAAVWRS"
     CDS_motif       15177..15287
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37410_0007"
                     /evalue="1.30E-16"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="IE189_RS37410"
                     /protein_end="699"
                     /protein_start="662"
                     /score="52.5"
                     /tool="antismash"
                     /translation="GIEPGAVIGHSQGEIAAAVVAGALSVQDGARVVVLRA"
     CDS_motif       15396..15434
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37410_0008"
                     /evalue="2.50E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="IE189_RS37410"
                     /protein_end="748"
                     /protein_start="735"
                     /score="11.2"
                     /tool="antismash"
                     /translation="ASVNGPSSTVVSG"
     CDS_motif       15504..15536
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37410_0009"
                     /evalue="4.90E-04"
                     /label="PKSI-AT-mM_m6"
                     /locus_tag="IE189_RS37410"
                     /protein_end="782"
                     /protein_start="771"
                     /score="12.8"
                     /tool="antismash"
                     /translation="VDYASHSAQVE"
     CDS_motif       15642..15689
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37410_0010"
                     /evalue="6.40E-05"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="IE189_RS37410"
                     /protein_end="833"
                     /protein_start="817"
                     /score="15.2"
                     /tool="antismash"
                     /translation="LDAGYWVTNLRQEVRF"
     CDS_motif       15732..15761
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37410_0011"
                     /evalue="3.30E-03"
                     /label="PKSI-AT-mM_m9"
                     /locus_tag="IE189_RS37410"
                     /protein_end="857"
                     /protein_start="847"
                     /score="10.1"
                     /tool="antismash"
                     /translation="FVECSPHPVL"
     aSDomain        16044..16562
                     /ASF="catalytic triad H,G,P found: False"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37410_PKS_DH.1"
                     /evalue="8.90E-57"
                     /label="IE189_RS37410_PKS_DH.1"
                     /locus_tag="IE189_RS37410"
                     /protein_end="1124"
                     /protein_start="951"
                     /score="184.0"
                     /tool="antismash"
                     /translation="HPLLGAAVEVAGGDQLLLTGRLSLHAHPWLADHAVQGTPVLTGAA
                     FAELALHAGERAGAEVVESLTVEAPLVVPESGGVQVQLSVGAPDEDGARELGVHARPGT
                     QEDGTPWVRYATARLVPDGARRTGAADDAGTVERLAQWPPPGAQPVSVANFHQRAADAG
                     QGYGPAFRGL"
     CDS_motif       16128..16202
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37410_0012"
                     /evalue="4.90E-09"
                     /label="PKSI-DH_m2"
                     /locus_tag="IE189_RS37410"
                     /protein_end="1004"
                     /protein_start="979"
                     /score="28.7"
                     /tool="antismash"
                     /translation="WLADHAVQGTPVLTGAAFAELALHA"
     CDS_motif       16947..16982
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37410_0013"
                     /evalue="1.10E+01"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="IE189_RS37410"
                     /protein_end="1264"
                     /protein_start="1252"
                     /score="-0.3"
                     /tool="antismash"
                     /translation="PGQTADWVVLGD"
     aSDomain        17526..18062
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37410_PKS_KR.1"
                     /evalue="8.00E-58"
                     /label="IE189_RS37410_PKS_KR.1"
                     /locus_tag="IE189_RS37410"
                     /protein_end="1624"
                     /protein_start="1445"
                     /score="187.3"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GTVLITGGTGALGRVLARHLVKQHGVRHLLLVSRRGRDADGAEAL
                     ERELSSLGATVSVEACDAADREALARVLAAVPADRPLTAVLHAAGALADRPLEALTAQD
                     VEHVFTPKVTAAANLHELTRESDLAAFVLFSSASGVLGSLAQPNYAAANAFLDALAAHR
                     RAAGLAGLSLAWGLWA"
     CDS_motif       17529..17630
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37410_0014"
                     /evalue="3.10E-11"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE189_RS37410"
                     /protein_end="1480"
                     /protein_start="1446"
                     /score="35.8"
                     /tool="antismash"
                     /translation="TVLITGGTGALGRVLARHLVKQHGVRHLLLVSRR"
     CDS_motif       17910..18017
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37410_0015"
                     /evalue="3.10E-17"
                     /label="PKSI-KR_m4"
                     /locus_tag="IE189_RS37410"
                     /protein_end="1609"
                     /protein_start="1573"
                     /score="55.1"
                     /tool="antismash"
                     /translation="AAFVLFSSASGVLGSLAQPNYAAANAFLDALAAHRR"
     aSDomain        18342..18593
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37410_PKS_PP.1"
                     /evalue="9.00E-30"
                     /label="IE189_RS37410_PKS_PP.1"
                     /locus_tag="IE189_RS37410"
                     /protein_end="1801"
                     /protein_start="1717"
                     /score="94.9"
                     /tool="antismash"
                     /translation="LAGLTRDEQLHRLVELTRAHVASVLGHGTPEAIEPDRPFKEIGFD
                     SLTALELRNRLGAATGLTLPATLVFDHPTLNATAALLLD"
     aSDomain        18627..18833
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37410_PKS_Docking_Cterm.
                     1"
                     /evalue="1.30E-16"
                     /label="IE189_RS37410_PKS_Docking_Cterm.1"
                     /locus_tag="IE189_RS37410"
                     /protein_end="1881"
                     /protein_start="1812"
                     /score="53.1"
                     /tool="antismash"
                     /translation="PALAELDRLEEALAAVPDDDTATRARVRERLQALLAGWNGAPRPS
                     DGGDEELDDATDSELFALLDDELD"
     misc_feature    18870..18884
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     gene            18904..25515
                     /locus_tag="IE189_RS37415"
                     /old_locus_tag="GCM10010496_76020"
     CDS             18904..25515
                     /EC_number="2.3.1.-"
                     /EC_number="6.4.-.-"
                     /NRPS_PKS="Domain: PKS_Docking_Nterm (3-30). E-value:
                     3.1e-14. Score: 44.2. Matches aSDomain:
                     nrpspksdomains_IE189_RS37415_PKS_Docking_Nterm.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (33-459). E-value:
                     9e-179. Score: 586.7. Matches aSDomain:
                     nrpspksdomains_IE189_RS37415_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (576-874). E-value: 1.2e-103.
                     Score: 338.5. Matches aSDomain:
                     nrpspksdomains_IE189_RS37415_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (943-1108). E-value: 2.4e-57.
                     Score: 185.9. Matches aSDomain:
                     nrpspksdomains_IE189_RS37415_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_ER (1443-1749). E-value: 1.5e-114.
                     Score: 374.2. Matches aSDomain:
                     nrpspksdomains_IE189_RS37415_PKS_ER.1"
                     /NRPS_PKS="Domain: PKS_KR (1758-1939). E-value: 7.5e-57.
                     Score: 184.1. Matches aSDomain:
                     nrpspksdomains_IE189_RS37415_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2036-2122). E-value: 2.4e-31.
                     Score: 99.9. Matches aSDomain:
                     nrpspksdomains_IE189_RS37415_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (2135-2202). E-value:
                     3.4e-10. Score: 32.6. Matches aSDomain:
                     nrpspksdomains_IE189_RS37415_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014180969.1"
                     /locus_tag="IE189_RS37415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_76020"
                     /product="type I polyketide synthase"
                     /protein_id="WP_189928438.1"
                     /sec_met_domain="mod_KS (E-value: 2.2e-223, bitscore:
                     732.2, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.5e-93, bitscore:
                     303.4, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 4.4e-104, bitscore:
                     338.5, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_N (E-value: 1.6e-09, bitscore: 28.2,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 3e-17, bitscore:
                     53.4, seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.6e-60, bitscore:
                     194.5, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.1e-14, bitscore:
                     43.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSEDKLRDYLKRATADLRRARRRIQELEEPEPVAVVSMACRYPG
                     SADTPEALWELLASGVDAISPFPVDRGWDLEALYDPDPDAEGRNYVRESGFLHDAGEFD
                     ADFFGINAREALIMDPQQRLLLETSWELFERAGIDPRSVRGSRTGVFVGAATVDYVTGH
                     QYVPEGLEGYTGVGSFASVISGRVAYSFGMEGPALTVDTACSSSLVALHLAVRSLRQGE
                     CAMALAGGVALMPTPQGFIAFSRQRALAPDGRCKAFADAADGFGPSEGAGMLLLERLSD
                     ARRNGHPVLALIRGTAVNQDGASNGLTAPNGPSQERVVRDALADARLTPAEVDAVEAHG
                     TGTTLGDPIEARALLTTYGRDRDPARPLWLGSVKSNFGHTAHAAGAAGVMKMVLALRNE
                     LLPRTLHVDRPSTHVDWTSGAVALLTEPVAWKRNGRPRRAGVSAFGISGTNAHVIVEEA
                     PQPEDGAAPPDGGGGSGASARPPLALPVVPWVLSARTPAALAAQAERLAAFAERRGEVP
                     DTDIGRSLATGRAALEHRAVVLAGDRARALAGLEAVRRGEPTAGVVTGTARPGAARVAF
                     VFPGQGSQWQGMAAGLLESSPVFAQRLTACDAALRPWTGCSVIDAVRGGEGAASLDDVV
                     VVQSALWAVMVSLAALWRSAGVEPAAVIGHSQGEIAAAVVAGALSLEDGARVVALRARA
                     IAGGLSGRGGMVSVPLPAGRVAARLARWEGRVGIASANGPSSTVVSGDPEALDELLADC
                     EADGVRARRIAVDYASHSAHVETIRDEVLTALDDIRPRGGAVPFHSTVTAGPLDTAGLD
                     AGYWYTNLRRTVRFEETVRGLLAGGIRFFVECSAHPVLAVGLQEIFDDAGADAVALGSL
                     RRDEGGPERFLTSLAEGHARGLPVDWDAVFAGTGARRVPDLPTYPFQRRHYWLEAEYRN
                     AGDAGDLGLTSAGHPLLGAAVRLAEGDRLLLTGRLSLKTHPWLADHAVGGTALVPGTAF
                     AELALEAAARTGCAGVAEMTLHSPLTVPARGAVHVQVEVDGPDDAGRRALTVHARPGDA
                     ADGDPWTRHATAFLAPPGPVTDGEALTAWPPPGAARLDTAGMYEPVPGGAYRFGPAFQG
                     LRSAWRLGDTVYAEAALPPELHQDAARFGVHPALLDAALHAIGFGGFLGEGTHLPFSWH
                     DVTLRAVGPAAVRVRVRAAGNDAVTVTLADAEGAPVATVGRLVFRPLPAGGDDTGDGLR
                     DSLFHVDWAPLPVDAAAPSGAGWAVLGGDGHGLVPALRGAGVFAGAHRGPAELAAAVAS
                     GAPAPDVALLSCPSDPATVAADGLPAAVRRATEGVLRVVQEWLADDRLRGVVLAVVTRR
                     AVAAGPGEDVEDLAHAGVWGLLRSAQMENPGRFLLVDLDGRDESRARAAAAVRAALTAD
                     EPQLALRLGAARVPRLARTPAGAFLVPPPGEAAWRLDTTGPGDLDRLALLPHPQALARL
                     TDNQVRVSVRAAGVNFRDVLVGLGMVPSQERLGSEGAGVVTEVGPGVTGVAVGDRVMGL
                     LPDPFGPVSVVDRRLVTRIPRGWTFEQAAGVPAAFLTAWFGLADLGGLREDETVLVHAA
                     TGGVGMAAVQLARYRGAEVFATAGEGKWDTLRRMGFDTGHIASSRTLDFEKKFHAATGG
                     RGVDVVLNSLANEFTDASLRLLPRGGRFLEMGKTDIRDPHEVAERHPGVVYRPYDLIDA
                     GADRIGEILDTLVRLFERRVLRPLPVRTWDVRRAPEAFRFMAQARHTGKLVLTVPRPPD
                     PDGTVLVTGGTGTLGGILARHLVTAHGARHLLLAGRRGPQAPGADGLREDLLARGAHTV
                     TVAACDTADREALSDLLASVPADRPLTAVVHAAGTTADGVLSSLTPQRLDDVLRPKADA
                     AFHLHELTRESDLAAFVLYSAGAGVLGNPGQANYAAANTFLDALAHQRRAAGLPAVSLA
                     WGYWAETSELTGRMDDSHVERMTRSGVLPIDAGHGMRLFDAARAAGEALLVPTRLDVSA
                     LRTGASTDVGPAMLRGLLGGRRQAPRQAARAGTAAVEARSLEARLAALPADEQRLLLED
                     LVRGHVAAVLGASGPEAVGAGRAFKDMGLDSLTAVELRNRLGAATGLTLPSTLVFDFPS
                     PRELAGHLHQELAPDGAAAAADGPDPQEARVRALLATVPLARLRAGGLLDTLLGLAEEP
                     APGTTGPAPDRNAGAIADMDLEDLVRAALGGTGS"
     aSDomain        18913..18993
                     /aSDomain="PKS_Docking_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37415_PKS_Docking_Nterm.
                     1"
                     /evalue="3.10E-14"
                     /label="IE189_RS37415_PKS_Docking_Nterm.1"
                     /locus_tag="IE189_RS37415"
                     /protein_end="30"
                     /protein_start="3"
                     /score="44.2"
                     /tool="antismash"
                     /translation="EDKLRDYLKRATADLRRARRRIQELEE"
     aSDomain        19003..20280
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37415_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="9.00E-179"
                     /label="IE189_RS37415_PKS_KS.1"
                     /locus_tag="IE189_RS37415"
                     /protein_end="459"
                     /protein_start="33"
                     /score="586.7"
                     /tool="antismash"
                     /translation="VAVVSMACRYPGSADTPEALWELLASGVDAISPFPVDRGWDLEAL
                     YDPDPDAEGRNYVRESGFLHDAGEFDADFFGINAREALIMDPQQRLLLETSWELFERAG
                     IDPRSVRGSRTGVFVGAATVDYVTGHQYVPEGLEGYTGVGSFASVISGRVAYSFGMEGP
                     ALTVDTACSSSLVALHLAVRSLRQGECAMALAGGVALMPTPQGFIAFSRQRALAPDGRC
                     KAFADAADGFGPSEGAGMLLLERLSDARRNGHPVLALIRGTAVNQDGASNGLTAPNGPS
                     QERVVRDALADARLTPAEVDAVEAHGTGTTLGDPIEARALLTTYGRDRDPARPLWLGSV
                     KSNFGHTAHAAGAAGVMKMVLALRNELLPRTLHVDRPSTHVDWTSGAVALLTEPVAWKR
                     NGRPRRAGVSAFGISGTNAHVIVEEAP"
     aSModule        19003..25269
                     /complete
                     /domains="nrpspksdomains_IE189_RS37415_PKS_KS.1"
                     /domains="nrpspksdomains_IE189_RS37415_PKS_AT.1"
                     /domains="nrpspksdomains_IE189_RS37415_PKS_DH.1"
                     /domains="nrpspksdomains_IE189_RS37415_PKS_ER.1"
                     /domains="nrpspksdomains_IE189_RS37415_PKS_KR.1"
                     /domains="nrpspksdomains_IE189_RS37415_PKS_PP.1"
                     /locus_tags="IE189_RS37415"
                     /monomer_pairings="mmal -> Me-redmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       19486..19533
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37415_0001"
                     /evalue="1.20E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE189_RS37415"
                     /protein_end="210"
                     /protein_start="194"
                     /score="20.4"
                     /tool="antismash"
                     /translation="GPALTVDTACSSSLVA"
     CDS_motif       19909..19953
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37415_0002"
                     /evalue="6.30E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE189_RS37415"
                     /protein_end="350"
                     /protein_start="335"
                     /score="12.1"
                     /tool="antismash"
                     /translation="VEAHGTGTTLGDPIE"
     CDS_motif       20629..20682
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37415_0003"
                     /evalue="2.10E-08"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="IE189_RS37415"
                     /protein_end="593"
                     /protein_start="575"
                     /score="26.0"
                     /tool="antismash"
                     /translation="FVFPGQGSQWQGMAAGLL"
     aSDomain        20632..21525
                     /ASF="Methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37415_PKS_AT.1"
                     /evalue="1.20E-103"
                     /label="IE189_RS37415_PKS_AT.1"
                     /locus_tag="IE189_RS37415"
                     /protein_end="874"
                     /protein_start="576"
                     /score="338.5"
                     /specificity="substrate consensus: mmal"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFPGQGSQWQGMAAGLLESSPVFAQRLTACDAALRPWTGCSVIDA
                     VRGGEGAASLDDVVVVQSALWAVMVSLAALWRSAGVEPAAVIGHSQGEIAAAVVAGALS
                     LEDGARVVALRARAIAGGLSGRGGMVSVPLPAGRVAARLARWEGRVGIASANGPSSTVV
                     SGDPEALDELLADCEADGVRARRIAVDYASHSAHVETIRDEVLTALDDIRPRGGAVPFH
                     STVTAGPLDTAGLDAGYWYTNLRRTVRFEETVRGLLAGGIRFFVECSAHPVLAVGLQEI
                     FDDAGADAVALGSLRRD"
     CDS_motif       20794..20865
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37415_0004"
                     /evalue="5.40E-07"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="IE189_RS37415"
                     /protein_end="654"
                     /protein_start="630"
                     /score="22.3"
                     /tool="antismash"
                     /translation="LDDVVVVQSALWAVMVSLAALWRS"
     CDS_motif       20869..20979
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37415_0005"
                     /evalue="2.40E-18"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="IE189_RS37415"
                     /protein_end="692"
                     /protein_start="655"
                     /score="57.9"
                     /tool="antismash"
                     /translation="GVEPAAVIGHSQGEIAAAVVAGALSLEDGARVVALRA"
     CDS_motif       21088..21129
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37415_0006"
                     /evalue="1.60E-02"
                     /label="PKSI-AT-mM_m5"
                     /locus_tag="IE189_RS37415"
                     /protein_end="742"
                     /protein_start="728"
                     /score="8.0"
                     /tool="antismash"
                     /translation="ASANGPSSTVVSGD"
     CDS_motif       21196..21228
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37415_0007"
                     /evalue="9.00E-04"
                     /label="PKSI-AT-mM_m6"
                     /locus_tag="IE189_RS37415"
                     /protein_end="775"
                     /protein_start="764"
                     /score="12.1"
                     /tool="antismash"
                     /translation="VDYASHSAHVE"
     CDS_motif       21334..21381
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37415_0008"
                     /evalue="3.30E-05"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="IE189_RS37415"
                     /protein_end="826"
                     /protein_start="810"
                     /score="16.0"
                     /tool="antismash"
                     /translation="LDAGYWYTNLRRTVRF"
     aSDomain        21733..22227
                     /ASF="catalytic triad H,G,P found: False"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37415_PKS_DH.1"
                     /evalue="2.40E-57"
                     /label="IE189_RS37415_PKS_DH.1"
                     /locus_tag="IE189_RS37415"
                     /protein_end="1108"
                     /protein_start="943"
                     /score="185.9"
                     /tool="antismash"
                     /translation="HPLLGAAVRLAEGDRLLLTGRLSLKTHPWLADHAVGGTALVPGTA
                     FAELALEAAARTGCAGVAEMTLHSPLTVPARGAVHVQVEVDGPDDAGRRALTVHARPGD
                     AADGDPWTRHATAFLAPPGPVTDGEALTAWPPPGAARLDTAGMYEPVPGGAYRFGPAFQ
                     GL"
     CDS_motif       21817..21894
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37415_0009"
                     /evalue="3.50E-11"
                     /label="PKSI-DH_m2"
                     /locus_tag="IE189_RS37415"
                     /protein_end="997"
                     /protein_start="971"
                     /score="35.5"
                     /tool="antismash"
                     /translation="WLADHAVGGTALVPGTAFAELALEAA"
     aSDomain        23233..24150
                     /ASF="ER domain putatively catalyzing 2R-configuration
                     product formation"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37415_PKS_ER.1"
                     /evalue="1.50E-114"
                     /label="IE189_RS37415_PKS_ER.1"
                     /locus_tag="IE189_RS37415"
                     /protein_end="1749"
                     /protein_start="1443"
                     /score="374.2"
                     /tool="antismash"
                     /translation="GDLDRLALLPHPQALARLTDNQVRVSVRAAGVNFRDVLVGLGMVP
                     SQERLGSEGAGVVTEVGPGVTGVAVGDRVMGLLPDPFGPVSVVDRRLVTRIPRGWTFEQ
                     AAGVPAAFLTAWFGLADLGGLREDETVLVHAATGGVGMAAVQLARYRGAEVFATAGEGK
                     WDTLRRMGFDTGHIASSRTLDFEKKFHAATGGRGVDVVLNSLANEFTDASLRLLPRGGR
                     FLEMGKTDIRDPHEVAERHPGVVYRPYDLIDAGADRIGEILDTLVRLFERRVLRPLPVR
                     TWDVRRAPEAFRFMAQARHTGKLVL"
     CDS_motif       23380..23418
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37415_0010"
                     /evalue="6.10E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="IE189_RS37415"
                     /protein_end="1505"
                     /protein_start="1492"
                     /score="9.7"
                     /tool="antismash"
                     /translation="LGSEGAGVVTEVG"
     CDS_motif       23545..23589
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37415_0011"
                     /evalue="6.60E-04"
                     /label="PKSI-ER_m4"
                     /locus_tag="IE189_RS37415"
                     /protein_end="1562"
                     /protein_start="1547"
                     /score="13.2"
                     /tool="antismash"
                     /translation="AAGVPAAFLTAWFGL"
     CDS_motif       23614..23676
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37415_0012"
                     /evalue="1.10E-09"
                     /label="PKSI-ER_m5"
                     /locus_tag="IE189_RS37415"
                     /protein_end="1591"
                     /protein_start="1570"
                     /score="30.5"
                     /tool="antismash"
                     /translation="DETVLVHAATGGVGMAAVQLA"
     CDS_motif       23809..23847
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37415_0013"
                     /evalue="1.10E-05"
                     /label="PKSI-ER_m7"
                     /locus_tag="IE189_RS37415"
                     /protein_end="1648"
                     /protein_start="1635"
                     /score="17.7"
                     /tool="antismash"
                     /translation="TGGRGVDVVLNSL"
     misc_feature    23872..23874
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS_motif       24103..24150
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37415_0014"
                     /evalue="9.20E-06"
                     /label="PKSI-ER_m9"
                     /locus_tag="IE189_RS37415"
                     /protein_end="1749"
                     /protein_start="1733"
                     /score="18.6"
                     /tool="antismash"
                     /translation="AFRFMAQARHTGKLVL"
     aSDomain        24178..24720
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37415_PKS_KR.1"
                     /evalue="7.50E-57"
                     /label="IE189_RS37415_PKS_KR.1"
                     /locus_tag="IE189_RS37415"
                     /protein_end="1939"
                     /protein_start="1758"
                     /score="184.1"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GTVLVTGGTGTLGGILARHLVTAHGARHLLLAGRRGPQAPGADGL
                     REDLLARGAHTVTVAACDTADREALSDLLASVPADRPLTAVVHAAGTTADGVLSSLTPQ
                     RLDDVLRPKADAAFHLHELTRESDLAAFVLYSAGAGVLGNPGQANYAAANTFLDALAHQ
                     RRAAGLPAVSLAWGYWAE"
     CDS_motif       24181..24282
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37415_0015"
                     /evalue="1.20E-08"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE189_RS37415"
                     /protein_end="1793"
                     /protein_start="1759"
                     /score="27.5"
                     /tool="antismash"
                     /translation="TVLVTGGTGTLGGILARHLVTAHGARHLLLAGRR"
     CDS_motif       24565..24672
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37415_0016"
                     /evalue="1.40E-19"
                     /label="PKSI-KR_m4"
                     /locus_tag="IE189_RS37415"
                     /protein_end="1923"
                     /protein_start="1887"
                     /score="62.7"
                     /tool="antismash"
                     /translation="AAFVLYSAGAGVLGNPGQANYAAANTFLDALAHQRR"
     aSDomain        25012..25269
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37415_PKS_PP.1"
                     /evalue="2.40E-31"
                     /label="IE189_RS37415_PKS_PP.1"
                     /locus_tag="IE189_RS37415"
                     /protein_end="2122"
                     /protein_start="2036"
                     /score="99.9"
                     /tool="antismash"
                     /translation="LAALPADEQRLLLEDLVRGHVAAVLGASGPEAVGAGRAFKDMGLD
                     SLTAVELRNRLGAATGLTLPSTLVFDFPSPRELAGHLHQEL"
     aSDomain        25309..25509
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37415_PKS_Docking_Cterm.
                     1"
                     /evalue="3.40E-10"
                     /label="IE189_RS37415_PKS_Docking_Cterm.1"
                     /locus_tag="IE189_RS37415"
                     /protein_end="2202"
                     /protein_start="2135"
                     /score="32.6"
                     /tool="antismash"
                     /translation="PQEARVRALLATVPLARLRAGGLLDTLLGLAEEPAPGTTGPAPDR
                     NAGAIADMDLEDLVRAALGGTG"
     gene            25599..29846
                     /locus_tag="IE189_RS39760"
                     /old_locus_tag="GCM10010496_76030"
     CDS             25599..29846
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (36-461). E-value:
                     5.6e-171. Score: 561.0. Matches aSDomain:
                     nrpspksdomains_IE189_RS39760_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (639-940). E-value: 3e-110.
                     Score: 360.2. Matches aSDomain:
                     nrpspksdomains_IE189_RS39760_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DHt (892-1018). E-value: 7.3e-07.
                     Score: 21.2. Matches aSDomain:
                     nrpspksdomains_IE189_RS39760_PKS_DHt.1"
                     /NRPS_PKS="Domain: PKS_PP (1035-1121). E-value: 9.7e-25.
                     Score: 78.7. Matches aSDomain:
                     nrpspksdomains_IE189_RS39760_PKS_PP.1"
                     /NRPS_PKS="Domain: Thioesterase (1204-1411). E-value:
                     6.9e-30. Score: 97.1. Matches aSDomain:
                     nrpspksdomains_IE189_RS39760_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014057116.1"
                     /locus_tag="IE189_RS39760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_76030"
                     /product="type I polyketide synthase"
                     /protein_id="WP_189928440.1"
                     /sec_met_domain="mod_KS (E-value: 2.3e-209, bitscore:
                     686.0, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.3e-84, bitscore:
                     274.2, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.1e-110, bitscore:
                     360.2, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6.9e-13, bitscore:
                     39.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 1.4e-23, bitscore:
                     74.8, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSTEQIIEALRAALTDNERLREQNRRLVAAASEPLAVVGMACRF
                     PGGADSPDLLWERLADGRDMMSPLPRDRGWDLDALLGTADGGPAASAAREGGFLADVSR
                     FDAELFGISPREALAMDPQQRVMLEVAWEAFEHSGLDPLSLKGSPTGVFLGVSYAAYGS
                     DVTHVPAEVQGYSMTGNVTSVASGRIAYTLGLEGPAVSVDTACSSSLVALHQAAHALRA
                     GECSLALVGGVSVMPTPALLVEFTRQRGMAGDGRAKAFAAAADGTAWAEGAAAVVVERL
                     SDARRHGHRVLALVRGSAVNQDGASNGLTAPNGAAQRRVIRAALDSAGLTPQEVDAVEA
                     HGTGTRLGDPIEARALFDTYGRDRDPAHPLWLGAVKSNFGHAGTAAGLAGLVKTVLAMR
                     AGRLPRTLHVDEPTRAVDWSSGTVRLLTEDVAWTRAGHPRRAGISSFGISGTNAHVIVE
                     EAPQAPDFPAPGTPQARGLTEPEGAVGAATAGDGTAAVTEGPGSARGTGAVPGAGRAPV
                     PEAASAPGEGTGRPEAAAAADRHTSGSGSTPAETPLPLAGRTGAALRAQAARLADHIAR
                     RTGVPLADVGLSLATTRARLPRRAVVVADGREEALRALRALAAGEPDPAVTEGEAETEN
                     RPAFLFTGQGAQRPGMGAGLYAAFPVFAAAFDETCGSLDRHLEHSLREVVLAAPGTRGA
                     ALLDTTAYTQPATFALQVALHRLWESWGAAPRFLIGHSVGEISAAHVSGVLSLDDAAAL
                     VTARGALMQALPPGGAMYAVQATPDELAPHLAGREAEVSLAAVNGPRSAVLSGDAEAVA
                     GVAAHWAERGRRTKRLRVGHAFHSARMEPMLDAFREVAAALSYRQPTVPVISNVTGRAA
                     APGELADPGYWVRHVRGTVRFLDGMRALADEHVTAYVELGPDAVLTAMARECLGGRAAA
                     RVLAPTLRRDRPETRTALTAVAAVHAHGVPLDWEAVFSGRGARRTDLPTYAFQGRRYWL
                     TSAPDAHAGDVVPTLLAQAPSRDRDPAAAGDGTPPPADVGERWADRLPALDEEARTALL
                     TGLVRRHVAAVLGHTSPEEVLVARDFGELGLDSMPAADLLTRLQAATGLDLPATAVLDH
                     PSCERLAAHLADRLADGVPVAAPPARPDGLAGLFLRACREGRAREAHELTAGLAAFRSS
                     FTDSAGLDRAPRTAWLCDGPDEPVLLCFPSFVWQQNFYTYAKLASGFRSGRAVATIGLP
                     GFEEGEPLPASVDALAEALADAARRAAAGRTFALLGHSGGGNVAAVVAARLERRGTPPG
                     ALVLLDTPAWGGGHGLGGERWGDAVQRALVERAALVARAADGAAEAWITARARYAGFDY
                     AVPHLGTPTLLVRATEPLPAQGGPDPADDGWRVAWALPHTVADAPGDHFSMLEADHAAK
                     TAQAVDDWLRGPR"
     aSDomain        25707..26981
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS39760_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="5.60E-171"
                     /label="IE189_RS39760_PKS_KS.1"
                     /locus_tag="IE189_RS39760"
                     /protein_end="461"
                     /protein_start="36"
                     /score="561.0"
                     /tool="antismash"
                     /translation="AVVGMACRFPGGADSPDLLWERLADGRDMMSPLPRDRGWDLDALL
                     GTADGGPAASAAREGGFLADVSRFDAELFGISPREALAMDPQQRVMLEVAWEAFEHSGL
                     DPLSLKGSPTGVFLGVSYAAYGSDVTHVPAEVQGYSMTGNVTSVASGRIAYTLGLEGPA
                     VSVDTACSSSLVALHQAAHALRAGECSLALVGGVSVMPTPALLVEFTRQRGMAGDGRAK
                     AFAAAADGTAWAEGAAAVVVERLSDARRHGHRVLALVRGSAVNQDGASNGLTAPNGAAQ
                     RRVIRAALDSAGLTPQEVDAVEAHGTGTRLGDPIEARALFDTYGRDRDPAHPLWLGAVK
                     SNFGHAGTAAGLAGLVKTVLAMRAGRLPRTLHVDEPTRAVDWSSGTVRLLTEDVAWTRA
                     GHPRRAGISSFGISGTNAHVIVEEAP"
     aSModule        25707..29831
                     /complete
                     /domains="nrpspksdomains_IE189_RS39760_PKS_KS.1"
                     /domains="nrpspksdomains_IE189_RS39760_PKS_AT.1"
                     /domains="nrpspksdomains_IE189_RS39760_PKS_DHt.1"
                     /domains="nrpspksdomains_IE189_RS39760_PKS_PP.1"
                     /domains="nrpspksdomains_IE189_RS39760_Thioesterase.1"
                     /final_module
                     /locus_tags="IE189_RS39760"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       26187..26234
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS39760_0001"
                     /evalue="1.60E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE189_RS39760"
                     /protein_end="212"
                     /protein_start="196"
                     /score="20.0"
                     /tool="antismash"
                     /translation="GPAVSVDTACSSSLVA"
     CDS_motif       26610..26654
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS39760_0002"
                     /evalue="3.00E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE189_RS39760"
                     /protein_end="352"
                     /protein_start="337"
                     /score="12.9"
                     /tool="antismash"
                     /translation="VEAHGTGTRLGDPIE"
     aSDomain        27516..28418
                     /ASF="Malonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS39760_PKS_AT.1"
                     /evalue="3.00E-110"
                     /label="IE189_RS39760_PKS_AT.1"
                     /locus_tag="IE189_RS39760"
                     /protein_end="940"
                     /protein_start="639"
                     /score="360.2"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFTGQGAQRPGMGAGLYAAFPVFAAAFDETCGSLDRHLEHSLREV
                     VLAAPGTRGAALLDTTAYTQPATFALQVALHRLWESWGAAPRFLIGHSVGEISAAHVSG
                     VLSLDDAAALVTARGALMQALPPGGAMYAVQATPDELAPHLAGREAEVSLAAVNGPRSA
                     VLSGDAEAVAGVAAHWAERGRRTKRLRVGHAFHSARMEPMLDAFREVAAALSYRQPTVP
                     VISNVTGRAAAPGELADPGYWVRHVRGTVRFLDGMRALADEHVTAYVELGPDAVLTAMA
                     RECLGGRAAARVLAPTLRRD"
     CDS_motif       27519..27566
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS39760_0003"
                     /evalue="7.20E-05"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="IE189_RS39760"
                     /protein_end="656"
                     /protein_start="640"
                     /score="15.5"
                     /tool="antismash"
                     /translation="FTGQGAQRPGMGAGLY"
     CDS_motif       27699..27758
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS39760_0004"
                     /evalue="2.20E-04"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="IE189_RS39760"
                     /protein_end="720"
                     /protein_start="700"
                     /score="14.4"
                     /tool="antismash"
                     /translation="AYTQPATFALQVALHRLWES"
     CDS_motif       27768..27884
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS39760_0005"
                     /evalue="1.30E-19"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="IE189_RS39760"
                     /protein_end="762"
                     /protein_start="723"
                     /score="62.4"
                     /tool="antismash"
                     /translation="APRFLIGHSVGEISAAHVSGVLSLDDAAALVTARGALMQ"
     CDS_motif       27978..28016
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS39760_0006"
                     /evalue="2.30E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="IE189_RS39760"
                     /protein_end="806"
                     /protein_start="793"
                     /score="11.3"
                     /tool="antismash"
                     /translation="AAVNGPRSAVLSG"
     CDS_motif       28239..28274
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS39760_0007"
                     /evalue="1.20E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="IE189_RS39760"
                     /protein_end="892"
                     /protein_start="880"
                     /score="15.4"
                     /tool="antismash"
                     /translation="YWVRHVRGTVRF"
     aSDomain        28275..28652
                     /aSDomain="PKS_DHt"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS39760_PKS_DHt.1"
                     /evalue="7.30E-07"
                     /label="IE189_RS39760_PKS_DHt.1"
                     /locus_tag="IE189_RS39760"
                     /protein_end="1018"
                     /protein_start="892"
                     /score="21.2"
                     /tool="antismash"
                     /translation="LDGMRALADEHVTAYVELGPDAVLTAMARECLGGRAAARVLAPTL
                     RRDRPETRTALTAVAAVHAHGVPLDWEAVFSGRGARRTDLPTYAFQGRRYWLTSAPDAH
                     AGDVVPTLLAQAPSRDRDPAAA"
     CDS_motif       28494..28523
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS39760_0008"
                     /evalue="6.00E+01"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="IE189_RS39760"
                     /protein_end="975"
                     /protein_start="965"
                     /score="-2.5"
                     /tool="antismash"
                     /translation="VFSGRGARRT"
     aSDomain        28704..28961
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS39760_PKS_PP.1"
                     /evalue="9.70E-25"
                     /label="IE189_RS39760_PKS_PP.1"
                     /locus_tag="IE189_RS39760"
                     /protein_end="1121"
                     /protein_start="1035"
                     /score="78.7"
                     /tool="antismash"
                     /translation="LPALDEEARTALLTGLVRRHVAAVLGHTSPEEVLVARDFGELGLD
                     SMPAADLLTRLQAATGLDLPATAVLDHPSCERLAAHLADRL"
     CDS_motif       28902..28970
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS39760_0009"
                     /evalue="6.60E+00"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="IE189_RS39760"
                     /protein_end="1124"
                     /protein_start="1101"
                     /score="0.0"
                     /tool="antismash"
                     /translation="TAVLDHPSCERLAAHLADRLADG"
     aSDomain        29211..29831
                     /ASF="active site serine present: True"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS39760_Thioesterase.1"
                     /evalue="6.90E-30"
                     /label="IE189_RS39760_Thioesterase.1"
                     /locus_tag="IE189_RS39760"
                     /protein_end="1411"
                     /protein_start="1204"
                     /score="97.1"
                     /tool="antismash"
                     /translation="TYAKLASGFRSGRAVATIGLPGFEEGEPLPASVDALAEALADAAR
                     RAAAGRTFALLGHSGGGNVAAVVAARLERRGTPPGALVLLDTPAWGGGHGLGGERWGDA
                     VQRALVERAALVARAADGAAEAWITARARYAGFDYAVPHLGTPTLLVRATEPLPAQGGP
                     DPADDGWRVAWALPHTVADAPGDHFSMLEADHAAKTAQAVDDWL"
     CDS_motif       29370..29426
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS39760_0010"
                     /evalue="5.20E-04"
                     /label="NRPS-te1"
                     /locus_tag="IE189_RS39760"
                     /protein_end="1276"
                     /protein_start="1257"
                     /score="12.6"
                     /tool="antismash"
                     /translation="ALLGHSGGGNVAAVVAARL"
     gene            29967..30749
                     /locus_tag="IE189_RS37425"
                     /old_locus_tag="GCM10010496_76040"
     CDS             29967..30749
                     /NRPS_PKS="Domain: Thioesterase (25-248). E-value: 7.8e-52.
                     Score: 168.9. Matches aSDomain:
                     nrpspksdomains_IE189_RS37425_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013166.4"
                     /locus_tag="IE189_RS37425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_76040"
                     /product="thioesterase II family protein"
                     /protein_id="WP_189928442.1"
                     /sec_met_domain="Thioesterase (E-value: 1.5e-52, bitscore:
                     169.5, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1e-16, bitscore:
                     52.8, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 4.9e-07, bitscore: 20.1,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPWDRAAGPWLTRYTPPRPAGGRIQLVCLPHAGGSATFFQPLAR
                     AFEALPDAPFEVLAVQYPGRQERRAEPLLDDLAALADRVAEALRHAGDAPLVLFGHSMG
                     ALVAWEAARRLCRPGDTPPAGLVVSGRGAPSLHRDVRLHLRTDAELVADLRYLSGTASD
                     LLTDPDVLGMVLPVLRGDYKAVDGYRYEPGSPLSCPVAVFLGDRDPWARQREARGWQEE
                     TTGPVTFRTFPGDHFYLTARWDAVALAVAESLAGVTAG"
     aSDomain        30042..30710
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37425_Thioesterase.1"
                     /evalue="7.80E-52"
                     /label="IE189_RS37425_Thioesterase.1"
                     /locus_tag="IE189_RS37425"
                     /protein_end="248"
                     /protein_start="25"
                     /score="168.9"
                     /tool="antismash"
                     /translation="QLVCLPHAGGSATFFQPLARAFEALPDAPFEVLAVQYPGRQERRA
                     EPLLDDLAALADRVAEALRHAGDAPLVLFGHSMGALVAWEAARRLCRPGDTPPAGLVVS
                     GRGAPSLHRDVRLHLRTDAELVADLRYLSGTASDLLTDPDVLGMVLPVLRGDYKAVDGY
                     RYEPGSPLSCPVAVFLGDRDPWARQREARGWQEETTGPVTFRTFPGDHFYLTARWDAVA
                     L"
     CDS_motif       30243..30311
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37425_0001"
                     /evalue="1.50E-08"
                     /label="NRPS-te1"
                     /locus_tag="IE189_RS37425"
                     /protein_end="115"
                     /protein_start="92"
                     /score="27.1"
                     /tool="antismash"
                     /translation="DAPLVLFGHSMGALVAWEAARRL"
     gene            30800..32218
                     /locus_tag="IE189_RS37430"
                     /old_locus_tag="GCM10010496_76050"
     CDS             30800..32218
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1246: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018384520.1"
                     /locus_tag="IE189_RS37430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_76050"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_189928444.1"
                     /transl_table=11
                     /translation="MSETTRAVVLGAGMAGMLAATTLARHVDAVTVLDRDRLPGDADPR
                     RGVPQARHTHVLWSGGARVIESLLPGTTDRLLDAGAHRIGLPEDLVSLTAYGWQRRFPE
                     TQFMIAASRSLLDWTVRDRAGADPRITVTGDTDIIGLRGDASAVTGVTYKPRREGTVSV
                     LDADVVVDATGRGSPVKRWLAALGLPPVQEDVIDSGMAYATRIFRAPPGARKKFPLVSV
                     YADHRAGVPGRNGILLPIEDGRWMVTLSGTRGGEPPTTEEGFTAYLRTLRHPLIADLVE
                     RAEPLTGVQASRSTANRRLYYDRLVEWPDGLVVLGDAVAAFNPVYGHGMSAAALSAAAL
                     GATLAERGLRPGTARAVQRAVGAVVDTPWSLGTSQDICYPDVLARTDDPRLTRHAAQRR
                     AQADLIGTAALADAAVCAAAMRVNTLSGVADDAFQAPEVRAALAGAAALDLPDGPTLSD
                     DEYAAARTAVPAGH"
     gene            32344..32880
                     /locus_tag="IE189_RS37435"
                     /old_locus_tag="GCM10010496_76060"
     CDS             32344..32880
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE189_RS37435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010496_76060"
                     /product="GbsR/MarR family transcriptional regulator"
                     /protein_id="WP_189928446.1"
                     /transl_table=11
                     /translation="MSSDDAGRQQDPDAERLRAWMERVTAWFMLQAGWPPIMGRTMAWL
                     MISEPPEQTAAQIAEAVQASRASLTTTLRLLTEARMVQAVTRAGERATYYRITEDAWSG
                     VLKRRLESMTSFADITAEGLRLFPEGEVRAARMREAHRMFTWLNSEAEPMWKRWDAVNR
                     GDRADDPNDEDGMPL"
     misc_feature    32875..32877
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            32877..34436
                     /locus_tag="IE189_RS37440"
                     /old_locus_tag="GCM10010496_76070"
     CDS             32877..34436
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004944183.1"
                     /locus_tag="IE189_RS37440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_76070"
                     /product="MFS transporter"
                     /protein_id="WP_189928448.1"
                     /transl_table=11
                     /translation="MSDVQSRKWWALGAIGLSLLAIGVDATILNVALPTVSADLDASTS
                     QLQWIVDAFTLVLAAVLLPAGLLGDKFGRKKFLVAALLLFGVASLLCAYCTSSGQLIAA
                     RAVLGLAAAFIVPLSTSVLLNIFETEAERTKAIAVIAVSQMLGLPLGPIIGGALLNHFW
                     WGSVFLINVPLVLLGVLAVAKLVPESRSAERVTIDLGGVVLSSAGLTALTYGAIEAGEK
                     GWDSTETAVALLAGAVLTGLFVLWELRVTAAGKDPLVDLGLFRGRGFVWGSVLSTIVSF
                     AMFGLMFALPQYFQAVLGSDALGTGLRLLPLIGGLLVGASVINKMPAQLGPRAVPALGF
                     LLVSVGLFMGTATETDSGYGYVAIWLVVIGAGLGLAMTRSMAAALNSLSKERSGVGSAV
                     VQALRQVGGAIGVAVLGAVANSAYRGNLDLPGTPDEIADAAGRSVSTGVAVAAKLRDPA
                     MLEEVRDAFMGAMHTLLYVCSGIALVAALLALAFMPKQAAVPAKDTEQESAEGKRITGS
                     VA"
     misc_feature    32925..32927
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            34699..36045
                     /gene="ccrA"
                     /locus_tag="IE189_RS37445"
                     /old_locus_tag="GCM10010496_76080"
     CDS             34699..36045
                     /EC_number="1.3.1.85"
                     /GO_function="GO:0043880 - crotonyl-CoA reductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (52-414). E-value: 8.8e-24.
                     Score: 76.1. Matches aSDomain:
                     nrpspksdomains_IE189_RS37445_PKS_ER.1"
                     /codon_start=1
                     /gene="ccrA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009712584.1"
                     /locus_tag="IE189_RS37445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_76080"
                     /product="crotonyl-CoA carboxylase/reductase"
                     /protein_id="WP_189928450.1"
                     /sec_met_domain="ADH_N (E-value: 2.3e-09, bitscore: 27.8,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.9e-30, bitscore:
                     95.5, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEAIVSAVLSDDARPEDIAALPLPESYRGAVIRKEDATMFEGLAT
                     RDKDPAKALRVEEVPTPQPGPGEALIAVMASAINYNTVWSAIFEPLPTFTFLERYARSG
                     DPDAVRHDQPYHVLGSDLAGVVLRTGPGVRGWKPGDRVVAHCLSIELQAPDGHDDTMLD
                     PEQRIWGFETNFGGLAELSLVKVNQLMPMPGHLTWEEAAASGLVNSTAYRQLVSRNGAR
                     MKQGDTVLIWGAAGGLGSYATQIALNGGAVPVCVVSGQRKAELVRSMGAELVIDRAQEG
                     YRFWKDESTPDPREWKRFGARIRKLTGGEDPDVVVEHPGRETFGASVYVTRRGGSVVTC
                     ASTSGYRHEYDNRYLWMSLKRIIGSHFANYREAWEANRLIAKGMIHPTLSTVYPLSAVG
                     TATQDVHRNRHSGKVGVLCLAPEPGLGVRNGELRERHLPAINRFRAPTD"
     aSDomain        34855..35940
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37445_PKS_ER.1"
                     /evalue="8.80E-24"
                     /label="IE189_RS37445_PKS_ER.1"
                     /locus_tag="IE189_RS37445"
                     /protein_end="414"
                     /protein_start="52"
                     /score="76.1"
                     /tool="antismash"
                     /translation="ALRVEEVPTPQPGPGEALIAVMASAINYNTVWSAIFEPLPTFTFL
                     ERYARSGDPDAVRHDQPYHVLGSDLAGVVLRTGPGVRGWKPGDRVVAHCLSIELQAPDG
                     HDDTMLDPEQRIWGFETNFGGLAELSLVKVNQLMPMPGHLTWEEAAASGLVNSTAYRQL
                     VSRNGARMKQGDTVLIWGAAGGLGSYATQIALNGGAVPVCVVSGQRKAELVRSMGAELV
                     IDRAQEGYRFWKDESTPDPREWKRFGARIRKLTGGEDPDVVVEHPGRETFGASVYVTRR
                     GGSVVTCASTSGYRHEYDNRYLWMSLKRIIGSHFANYREAWEANRLIAKGMIHPTLSTV
                     YPLSAVGTATQDVHRNRHSGKV"
     CDS_motif       35374..35436
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37445_0001"
                     /evalue="1.50E-04"
                     /label="PKSI-ER_m5"
                     /locus_tag="IE189_RS37445"
                     /protein_end="246"
                     /protein_start="225"
                     /score="14.5"
                     /tool="antismash"
                     /translation="GDTVLIWGAAGGLGSYATQIA"
     gene            complement(36150..36974)
                     /locus_tag="IE189_RS37450"
                     /old_locus_tag="GCM10010496_76090"
     CDS             complement(36150..36974)
                     /NRPS_PKS="Domain: Thioesterase (35-260). E-value: 2.8e-53.
                     Score: 173.6. Matches aSDomain:
                     nrpspksdomains_IE189_RS37450_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010638157.1"
                     /locus_tag="IE189_RS37450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_76090"
                     /product="thioesterase II family protein"
                     /protein_id="WP_189928453.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 6.7e-16, bitscore:
                     50.1, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 5.9e-52, bitscore:
                     167.6, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTDRSTGTGAPGGAADAGDTLWVRRFHPVADARVRVVFLPHAGG
                     SASFFFPFSAALAATGRVEALSVQYPGRQDRRDEAPLRSLAELADGVHRALRGWTDRPL
                     VLMGHSMGAVIAYEVARLGEREGNGVPLGVIASGRRAPSVHRVEDAHRLGDKEFLAEVR
                     SLSGTASALLDDEEIVRMILPGLRADYQAVETHEPAPEPLLRCPVGVVTGDADPRVTPE
                     EAQAWRRHTTGGFRFRVFPGGHFYLNDHQASVADTIDEYVAAFAKEAAADAG"
     aSDomain        complement(36195..36869)
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS37450_Thioesterase.1"
                     /evalue="2.80E-53"
                     /label="IE189_RS37450_Thioesterase.1"
                     /locus_tag="IE189_RS37450"
                     /protein_end="260"
                     /protein_start="35"
                     /score="173.6"
                     /tool="antismash"
                     /translation="RVVFLPHAGGSASFFFPFSAALAATGRVEALSVQYPGRQDRRDEA
                     PLRSLAELADGVHRALRGWTDRPLVLMGHSMGAVIAYEVARLGEREGNGVPLGVIASGR
                     RAPSVHRVEDAHRLGDKEFLAEVRSLSGTASALLDDEEIVRMILPGLRADYQAVETHEP
                     APEPLLRCPVGVVTGDADPRVTPEEAQAWRRHTTGGFRFRVFPGGHFYLNDHQASVADT
                     IDE"
     CDS_motif       complement(36612..36674)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS37450_0001"
                     /evalue="1.30E-09"
                     /label="NRPS-te1"
                     /locus_tag="IE189_RS37450"
                     /protein_end="121"
                     /protein_start="100"
                     /score="30.5"
                     /tool="antismash"
                     /translation="DRPLVLMGHSMGAVIAYEVAR"
     gene            37277..37567
                     /locus_tag="IE189_RS37455"
                     /old_locus_tag="GCM10010496_76100"
     CDS             37277..37567
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020133269.1"
                     /locus_tag="IE189_RS37455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_76100"
                     /product="SCO0607 family lipoprotein"
                     /protein_id="WP_189928455.1"
                     /transl_table=11
                     /translation="MRIAAAAFASVAAVVALTGCSGWEYREDVCASGEYPVLSVGGTGS
                     ACVSDGQEPPSGFARYPQGKVPQEVGDKWDTYWDTHTLDKEGNVIDAPAEG"
     gene            complement(<37784..>38309)
                     /locus_tag="IE189_RS39405"
                     /pseudo=""
     CDS             complement(<37784..38309)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020114989.1"
                     /locus_tag="IE189_RS39405"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPDRQALCGIQCVLHTGIQWEHLPQELGFGSGMPVGDRRPRGNGP
                     ARGTSCIWCC"
     gene            complement(38409..39113)
                     /locus_tag="IE189_RS37465"
                     /old_locus_tag="GCM10010496_76110"
     CDS             complement(38409..39113)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018514251.1"
                     /locus_tag="IE189_RS37465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_76110"
                     /product="hypothetical protein"
                     /protein_id="WP_189928457.1"
                     /transl_table=11
                     /translation="MDSTGAESSTGTGAEQDEAAVGLTKAAPAPAPAPTPAEAPDIQSH
                     DTFVIKKSLSLTTGEYVVSVARPDGSEGEPVAYARQKRLSLRGQVTVYTDASRKSVLAA
                     FKGRDHEVGYMYDVRDASGRSFGSFHEDAGASFLRRTWQVRQPGTTKLTCRERSRVVAF
                     VRFVWEFVPYLEYVPFIWPYRFEYTESGKPLMTVTKKLGLHTRYVLEILAPDIDRRLAI
                     AHTLALDALEVD"
     gene            39410..41185
                     /locus_tag="IE189_RS37470"
                     /old_locus_tag="GCM10010496_76120"
     CDS             39410..41185
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018514252.1"
                     /locus_tag="IE189_RS37470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_76120"
                     /product="sensor histidine kinase"
                     /protein_id="WP_229901607.1"
                     /transl_table=11
                     /translation="MIWSPARIVGEAVLAVTLAGLATGIGAWMDTIGAQTVLLAGAMAL
                     LAPARHALPATALILSAPLAGGWNVMASVLLVCAAWSAGRRITEPWRVAAAFGAACVLH
                     TVPDLYQDIASGVAPVLLVTLGWNVATFLTLAVVPALVGRYRDQRRRLLDALWLNNEQL
                     RREQAMVAREARLLERNRIAHDMHDSLGHQLALISVHAGALQVDPELTANQREAVRILR
                     GASVTAMAELRAAVGVLHDEAEYGEYREHQGHQPQSVGDAASVSYAPRTIAAIDGLVES
                     SRGAGTAVSLDRSGVRRPLAPAADHEAYRIVQEGLTNAHKHAPGAPIRLALRYEPDSLV
                     VEVTNGPVSGGAPEVPPEISGGQGLKGLCERVGRVGGMVHTGPTEDGGFRIAGMLPYGE
                     ESKAGSGAEGRVGNLGGHGAGSGARGGAGPNGATSVVSARDFRGQRRPGAVGDGGTVIN
                     GADPQREFTTTMSTRKNVAIGCAVTAVVLVAGVIGLGVWGIGVMTEEVKKADISPSVYE
                     EAKVGDAEADIQARLPEEDSWLTSDLADQGPKLPEGATCRHFTSKDDQGADALTVFRFC
                     FQDGKLVSKETYKAK"
     gene            41291..41968
                     /locus_tag="IE189_RS37475"
                     /old_locus_tag="GCM10010496_76130"
     CDS             41291..41968
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018489391.1"
                     /locus_tag="IE189_RS37475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_76130"
                     /product="response regulator transcription factor"
                     /protein_id="WP_189928461.1"
                     /transl_table=11
                     /translation="MIRVLVADDEPLIRAGIRMILTSADDIDVIAEAGDGREAVETARG
                     GGVDVALLDIQMPVMDGLTALVELGRAAPKVRVLILTTFGERDNVLRTLGHGGAGFLLK
                     DSAPDELIQAVRAAAAGNAYLSPAATRHVADALSATGATTRGEAARRRLDGLTTREREV
                     LALLGEGLSNADAGRRLHMSEATVKTYVSRILTKLDCDNRVQAALLARDAGLQPGGLQP
                     GRH"
     misc_feature    41338..41353
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.1"
                     /tool="antismash"
     gene            42196..42737
                     /locus_tag="IE189_RS39410"
                     /pseudo=""
     CDS             42196..42737
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040391.3"
                     /locus_tag="IE189_RS39410"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="DUF6368 family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSGPVLVIELAEPVPLISIQRLRELLVRSSSHFEEKRVGEYELNI
                     HAESLGVAYTGGIDGGRPVMVSLMGPGIGDEAVFEAEHADEVDQEPLIGFTPTQPSTS"
     gene            complement(43042..43242)
                     /locus_tag="IE189_RS37490"
                     /old_locus_tag="GCM10010496_76170"
     CDS             complement(43042..43242)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013001788.1"
                     /locus_tag="IE189_RS37490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_76170"
                     /product="hypothetical protein"
                     /protein_id="WP_189928467.1"
                     /transl_table=11
                     /translation="MNHTFPALLLLALAVAVLFSVIAAAIAFALARWEGAAVPAALSRC
                     GIAFAASLTLCLAVFAALDRT"
     misc_feature    complement(44003..44018)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.07"
                     /tool="antismash"
     misc_feature    complement(44553..44568)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.86"
                     /tool="antismash"
     gene            <45021..46514
                     /locus_tag="IE189_RS37495"
                     /pseudo=""
     CDS             <45021..46514
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019072468.1"
                     /locus_tag="IE189_RS37495"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="diguanylate cyclase"
                     /pseudo=""
                     /transl_table=11
                     /translation="LHLARSLADTLQIVADGLVTGLGYELACVNLVRTDGNLVVASFAG
                     NPAAEELITGRVGSRESWERRLSMGEAWGDLRFIPHTEGWVLDDDDVPQWYTDGPAPSS
                     EDEWHPSDRLFAPLYTRSASGASRGELLGVISVDRPLTRRRPTPDERRDLEEYAFQAAI
                     AISNARLRANMQRALVRQEREQQALRASEESFRQAFEYAPNGMAIAEMGGDHHGRILQT
                     NDALCRMLGRPASAMRRYSFSDLVHPEDIGTLLRTSSEGGHAELRLGRRDGTYLWTSLR
                     NSVVADADDGPRFLLTHVEDIEERKHREFELAHRASHDDLTGLPNSAELHARIDARLCA
                     LPEHGADAAGEPHDNSYLGYDDQAAPPHTHVWAPVREDDTHGLALIFFALRDFKAINTQ
                     FGHDAGDSVLVEVARRLRQAIRDNDTVARYGGDEFVVLADDFGPADAHTAAVWMQSQIH
                     LPISLGGQVVRMHAGVGIAWAQCGTSPSDTLRAARGFAS"
     misc_feature    45528..45530
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(46722..47336)
                     /locus_tag="IE189_RS37500"
                     /old_locus_tag="GCM10010496_76190"
     CDS             complement(46722..47336)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007268940.1"
                     /locus_tag="IE189_RS37500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_76190"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_189928469.1"
                     /transl_table=11
                     /translation="MNRIPDLRGEHLRLRELHAGDHDTFARILTHRALTRYLGNDRMDA
                     AQAHDAFAQCLAQPHTHPRRKYTLAICAPDDDTMVGTMGLLVEDYGSNAMLTALVMLPG
                     APVRGHGHEAGRLLMAYAFGHLGLHRIWAGHRSDHHHMAQIMHAAGLRPEATLRQLFRT
                     RGCWHDVTTYATVAPEWKRQATETELAILDSTPRPVEPVPR"
     gene            complement(47333..48415)
                     /locus_tag="IE189_RS37505"
                     /old_locus_tag="GCM10010496_76200"
     CDS             complement(47333..48415)
                     /GO_function="GO:0008641 - ubiquitin-like modifier
                     activating enzyme activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018530120.1"
                     /locus_tag="IE189_RS37505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_76200"
                     /product="ThiF family adenylyltransferase"
                     /protein_id="WP_229901608.1"
                     /sec_met_domain="ThiF (E-value: 5.6e-15, bitscore: 45.8,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLDPSRPAGAQALSMLRGSPLVREVHDRIEDQVAELVGCQAPGE
                     SFGPQALDRAVAKVVSGRPDRYGRWAWYPWSGRLVHVLPEAEFRLVRTDRNRNKITRGQ
                     QQRLLLRRIGVIGLSVGSSAALTCAMEGVGGAFRLADFDHLGLSNLNRLRAGVHELGLE
                     KSVLCARRMYELDPYLDIEVHRGGVNEENVGDFFGDQDNGLDLLVEECDTLWVKVAARE
                     HARRRRVPVLMDTNDRGVLDIERFDLDGNRPLFHGRIGTTTAADVVGLSREETIRFLLT
                     IVDGQRLSPAMSDALTRVGRTLSSWPQLASGVMLGAALITDTARRILLGEPVPSGRHWA
                     DLEALIPTVSTLPTPHGAAL"
     misc_feature    48559..48574
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.1"
                     /tool="antismash"
ORIGIN
        1 gggccatgtg cgcggcctgc ccggcgtcga ctggcgggcc gtcttcgccg ggaccggcgc
       61 cgcacgggtg gacctgccca cctacccctt ccagcgcacg cgctactggc tggacgacct
      121 cgccgcgtcc gtgaccgatg aggacgggag cgcggccgac ccggccgagg cggagttctg
      181 ggacgcggtg gaacgcggtg acctcgacgg cgtcgccgcg gaactggagg tcggcaccga
      241 tccgctcggg gcggtcctgc ccgccctgtc cgcctggcgc aggcgccgcc gcgaacgctc
      301 ccaggtcgac cgctggcgct accgcaccgt ctggcggccc ctcgaggccg ggagcgcgac
      361 gcgctcctcc aacgacggtg ccctcgccac cacccccgtc ctcacagggc gctggctgct
      421 gctcatcccg gcggacctcg ccacggaccc gtgggccgac gccgccgaga ggaccctgac
      481 gggccacggc gcggaggtgg aacgcgtgac catcgacacc gctgacaccg tgaacgccgc
      541 ggacgcttcg gacggcgggc gcgaccggtt cgccggactg ctgcgcgacg gcaccgccgg
      601 cgtcctgtcc ctcctcgccc tggacgacgc cccgcacccc ggccaccccg ccgttcccgc
      661 gagcctcgcc gcccatctgg cgctcgctca ggccatggcc ggctccggga ccacggcacg
      721 gctgtgggcc gccacccgag gcggtgtgct caccggccgc agcgaccccc ggacgagccc
      781 gggccaggcc cagacctggg gcctcgggcg ggtcgtcgcc ctggaggaac ccgcgctgtg
      841 gggcggcctc gtcgacctgc ccgacaccgc cgacgacgcg gccgccgccc ggctggccgc
      901 ggtcctcggc ggcctccccg cccccgacgg acacgggcag gaggaccagc tcgccatccg
      961 cccggacggc gtccacgcgg cccgcctcgt ccgtgccccg ctcggcgacg agccggcgcg
     1021 acgcgcctgg cagcccggcg gcaccgtgct gatcaccggc ggcaccggag ggatcggctc
     1081 caaggtcgcg cgctggttcg cgggcaacgg agcgcggcac ctgctgctca ccggccgccg
     1141 cgggcccggc gcacccggcg ccgcggaact ccgcgcggaa ctggagcaac tgggcgccca
     1201 ggtgaccatc accgcctgcg acatggccga ccgggacgcg gtcgccgccc tggtggcggc
     1261 cgtaccgcag gagcacccgc tcaccgcggt cgtccacgcg gccggcgtgc cgcagggcta
     1321 caccccgttc accgacacca cggccggtga cctcgcggag gtcaccgcgg gcaaggtcgc
     1381 gggcgccgcc cacctggacg acgtgctcgc ggacacgccc ctggacgcct tcgtgctgtt
     1441 ctcgtccaac gcggccgtat ggggcagcgg cggccaggcc gcctacgcgg cgggcaacgc
     1501 gtacctcgac gcgctcgccg cgcggcgccg cgccctcggc aggaccgcca cctccctcgc
     1561 ctggggcgcc tggggcgggg gcggcatgat ggccgccgag ggggccgccg aatacatggg
     1621 ccgccgcggc gtgctggaga tggcgcccga gccggccacg gccgccatgg tgcaggccgt
     1681 ggaacacgac gagaccaccg tcgcggtggc ggacgtcgag tgggagcgtt tcgtcctcgg
     1741 cttcaccgcc cgccgcccca gcccgctgct cgccgagatc cccgaggtcc gggcagccct
     1801 gcgcgaggac gcggacgagc aggacgccgg gcaggacacc gcccgggccg cgctcaccgc
     1861 ccgcctggcc ggcatgacgg ggcacgaaca gctcaggacg ctcatggagc tggtccgcga
     1921 ggaggccgcg gccgtcctgc ggcacgacgg caccgacggc atccagggcg gtcgggcgtt
     1981 caaggagctg ggcttcgact cgctgaccgc cgtagaactg cgcaaccgcc tcaaggccgc
     2041 caccggcctg cggttgtccg cggccgtcgt cttcgaccac ccgaccccgg ccgcgctcgc
     2101 cgcccacctg cgcggcctgc tggtcgcgga cggcgcccag aaggaaaccg gcgccgcgat
     2161 ggacgggctc aaggccctcg aggactccgc cgccgcactc gccggcgacc gcgacgcgga
     2221 cggcaaggcc aggatcgtcg aacgcctcga ggcgctgctg tggaagctcc gcgacaacgg
     2281 cgcggaggcc gggtcgggtc cgggcgacga cgcggacccc gcaccggaca ccgacgacct
     2341 cgcggcggcc acggccgagg acatgttcga cctgctcgac cgcgaactcg gcaccgcctg
     2401 acccgccgcc cggacacggc acggactcga cgcgcgactg ggggaccaga ggcaatggca
     2461 gagaacgaag agaaactgct cgagtatctg aagcgggtga cgggcgacct ccgccagacg
     2521 cagcgccgcc tgcgcgaggc cgaggcggcg cacagcgaac ctgtcgccat cgtcgggatg
     2581 gcctgccgct acccgggcgg ggtcgactcc ccggaggacc tgtgggagct cgtcgcccgc
     2641 ggcggcgacg ccgtcaccgg tttccccacc gaccgggggt gggacgtcga gggccagtac
     2701 gaccccgacc ccgcccgcag cgggaagaac tacgtccgcg ccggcggctt cctgcacggc
     2761 gtcaccgact tcgacgccgg gttcttcggc atctcccccc gggaggccct ggccatggac
     2821 ccccagcagc ggctgctgct ggaaggcgcg tgggagctgt tcgaacgctc cggcatcgac
     2881 cccacatcgc tcaagggcag ccccaccggc accttcatcg gcttcagctc ggcggactac
     2941 ggctgggagc tgcccaggat ccccgagtcc gtcgagggct actacgccac cggcaacttc
     3001 gccagcgtca tgtccgggcg gatcgcctac accttcggcc tcgaaggact cgcggtcacc
     3061 gtggacgcgg cctgctcctc ctctctggtc gccttgcacc tggccgccca ggcgctgcgc
     3121 tcgggcgagt gctccctggc cgtcgccggt ggcgtcaccg tgatgtccac cgcggtcggg
     3181 tacgccgagt tcagccggca gcgcgcactg tcccccgacg gaaggtgccg cgcgttctcc
     3241 gcctccgccg acggcttcgg cccggccgaa gggctgggcc tgctgctcgt ggagcggctc
     3301 cgcgacgccc gtcgcaacgg tcaccaggtc ctcgccgtgg tccggggctc ggccgtcaac
     3361 caggacggcg ccagcaacgg cctcaccgca cccaacggcc ccgcccagga gcgcgtgatc
     3421 cgcgccgccc tgcgcaacgc ccgcgtgtcc cccgacgagg tggacgcggt cgaggcgcac
     3481 ggcaccggca ccccgctcgg cgaccccatc gaagcccacg ccctcctgtc cacctacggc
     3541 gaacgccgcc ccaaggagcg cccgttgtgg ctgggctccg tcaagtccaa catcggccac
     3601 acctcggccg cggccggggt cgcgggcgtc atcaagatgg tgcaggccat gcggcacggc
     3661 gtcctgccca agacgctgca cgccgacgag cccacacccc acgtcgactg gtcccccggc
     3721 accgtgcgcc tgctcagcga accccggccg tggcccgaca ccggtgaccg cccgcgccgg
     3781 gccggcgtgt ccgcgttcgg catcagcggc accaacaccc acgtcgtcct cgaacaggcc
     3841 ccggccgcga accccaccgc caccgagccc gcgcccgccc cacgcccact gtccgggctc
     3901 accgcggcga ccgtgccgtg gccgctctcg gcacgctccg cacccgcact gcgcgaccag
     3961 gcggaactcc tgagcgccca cctgagcgag aaccccggaa cccccctcga cggcgtcggc
     4021 cgcaccctgg ccaccgcccg tgccgcgctg gaacaccgcg ccgtactcct ggcagccgac
     4081 cgcgacgagg ccctcgccgc cctggccgcc gtgtccggcg ggcacccgga cgcacgtgtg
     4141 gtgcacggcg tcactctgac ggacgggacc gaacaggaac tggccggccg ggtggtgttc
     4201 gtgttcccgg gtcagggctc gcagtggctc gggatgggtg cggggttgtg ggagtcgtcg
     4261 ccggtgttcc gggagcggct tcaggagtgt gacgcggcgc tgtctgtgct ggtggactgg
     4321 tcggtgaccg atgtggtgcg gggtgtgccg gatgcggctt cgctggacga tgtggtggtt
     4381 gttcaggcgt cgttgtgggc ggtgatggtg tcgctggcgg cggtgtggcg ttcggtgggt
     4441 gtggagccgg gtgcggtgat cgggcattcg cagggcgaga tcgctgctgc tgtggtggcg
     4501 ggtgggttgt ccgtcgagga cggtgcccgg gtggtcgtgc tgcgggcgag ggcgatcgcg
     4561 cggagcctgt cgggccacgg cgggatggtg tcggtggcca cgggtgcgga ccgggtaagg
     4621 gagttgatcg cgggctgggg tgaacgtatc tcgatcgcct cggtcaacgg cccctcgtcg
     4681 acggtggttt cgggtgagcc ggtggctttg gacgagctga tggctgcctg cgagagcgaa
     4741 gggatacggg cgcgtcgtat cgcggtggat tacgcctcgc actcgccgca ggtggagtcg
     4801 atccgggagc aggtcaccga cgccctcgcg gacgttgaac cccgtaccgc gcacgtcccg
     4861 ttctactcga cggtgaccgg ttcggtgatc gacacgagcg gcctggatgc cggttattgg
     4921 gtgaccaatc tgcgtcagga ggtgcggttc gacgtcacgg tccgtgagtt gctggcggac
     4981 ggcttcggtt acttcgtgga atgcagccct cacccggtcc tgaccgtcgg catgcaggag
     5041 accttcgacg acgtcgcgga cgtccaggcc gtggcgctcg gcaccctccg ccgcgacgaa
     5101 ggcggtccgg agcgcttctt gacctccctc gccgagggct acgtgcgcgg cctgtccgtc
     5161 gactggaacg ccgtcttcgc cgggacaggt gacgacgagc cgctgctcga cctgccgacc
     5221 tacgcgttcc agcgcaggcg ttactggctc gacgggggtg ccgcgtccgt caccgacccg
     5281 gccggtctcg ggctcggtga cagcggtcat ccgctgctgg gagcaacggt cggggtggcg
     5341 gacgacgagc ggctgctgct caccgggctg ctctcccgcc gggcccagcc ctggctggcc
     5401 gaccacgccg tccatggcag ggcgctggtc ggcggcgcca ccgtcgccga actggcgctc
     5461 gccgctgcgg tgcaggccgg tgccgaccgc gtggagacgc tggtcgtgga ggcggggctg
     5521 ccgctgcccg agggaggcgg cgtgcaggtc cagttgtccg tcggcgcacc ggacggcgag
     5581 gggcggcgcg acctggcgct ctacgcgcgc cccggcgacg cgttgcccga caccccgtgg
     5641 acccggcacg cccggggcac cgtggcggcg tccccgtcca cggcccctgc cggggagccg
     5701 gccggtgtgt ggccgcccga ggacgccgtg cccgtgggga ccggtgaggt gtacgagcgg
     5761 ctggcttccg ccgggtacgg gtacggtccc gcgttccagg ggctgcgggc cctgtggcga
     5821 cggggcgggg acctcttcgc cgaggtcgcg ctgacggagg aacaggcgcg gggcgcgggc
     5881 gcgttcggtc tgcacccggc cctgctggac gccgccctgc accccgtgct gctcgatcac
     5941 ctggacggcg ccgacccggc ggtgctgctg ccggccgagt ggcacggcct cgccctgcac
     6001 gcggtgggcg ccaccttgct gcgggtccgg atccggcccg ccggacccgg cgccgtgtcg
     6061 ctgttcctcg ccgacgcggc cggtgccccg gtggcctcgg tcgccgaggt gcgactgcgc
     6121 gggcacagcc ccgaggagct ggccggtgcc ccgggggcgc tccgggacgc gctgttccga
     6181 ctcgagtggg ccccgttcga ccggccgctc tccgcggccg cccccgtcgg cgggtggacc
     6241 gtggtcggcc cggacgagct cgggatcggc tcggacgcgg agcgggacgc cgaaccgggt
     6301 ctcgccctcg cctcgttcgc ggcgtttccg gcggccgacc ccgctgccgc gctcgcccca
     6361 cgggtgcacg aggcggccgc ggaggccctc ggcctggtgc agaaatggct cgtcgaccag
     6421 cgctccgaat ccgtccctct ggtgctggtg accagcgagg cggtggccgc cgcacccggc
     6481 gaccggatca ccgacctcgt ccacgcccca ctgtggggcc tggtccggtc cgcgcaggcc
     6541 gagtacccgc ccggcaggtt cctcctggtg gacgtggacg accacgaggg gtcccgcacg
     6601 gcgctcgcgg cagcggcagc cgccgcgctg gaggcgggcg agccgcaact ggccgtgcgg
     6661 aacggcaccg tgctggtgcc acgcctggtg cgcgcgggga cggtggaggg cgccgcggcg
     6721 ccgttccccg aatccggcac cgtgctgatc accggcggca ccggaacctc cggcgccctc
     6781 gtcgcccggc acctcgtggc cgcccacggg gcgcggcacc tgctgctggt gtcccgccga
     6841 ggcccggacg cccccggtgc cggggccctc gcggaggagc tgcgcgggct gggtgccgac
     6901 accgtggacg tcgtggcctg cgacgcggcc gaccgggacg ccctggcgga cgtcgtcgac
     6961 tccgtgccgg ggaaccgtcc gctgaccgca gtggtgcacg cggccggggt gctggacgac
     7021 gccctcaccg cgtccctgac cgccccgcag atgggacggg tgctgcggcc gaaggccgac
     7081 gccgcgctcg tcctgcacga actgacccgc gaccgcgaac tgtcggcgtt cgtcctgttc
     7141 tcgtcggccg ccggcacgct cggcaacgcc ggacaggcca acctcgccgc cgccaacgcc
     7201 ttcctcgacg ccctcgccgc acgccggcgc gccctcggcc tgccggccgt ctccctggcc
     7261 tggggcccct gggccctggg ggaggacgac ggcagggcgg cgggcggggg agtgcggccc
     7321 ttctccccgg aggaagggct ggggctgctg gacgcggccc tggcggacgg cgccgccctc
     7381 accgtgccgg tacggctcga cctcccggcg ctcgaggccg ccgcggcctc ggggacgctc
     7441 cccgcaccgc tgcgccgcct ggtgcgcgtc cccgcccgtc gcgcggcggc cgcgggaccg
     7501 ggcacggcgg cgggcaccgg tctcgcccgc gggctggccg tggtgcccga ggccgagcgg
     7561 cgcaggatcc tgctcgacct ggtgcgcacc gaggtcgcgg cggtcctgcg gcacgcgacc
     7621 gtggacgacg tggaggccga ccgggcgttc aaggagctgg gcttcgactc cctgaccgcc
     7681 gtggagctgc gcaaccggct cggcgccgcg accggcctgc ggctgccgcc cacgctggtc
     7741 ttcacctacc cgacccccgc ggccctggtg cgtttcctgc tcgacgagat cgcaccgggg
     7801 accggggagg attccgcaac ccccgtcctc gccgacctgg agcggctcga cgcgagcttg
     7861 tccggcctcg ccgcggacgc cgtcacccgc gacaggatca cgcggcgcct ggaagcgctg
     7921 ctgtggaagt ggagcggtga accggacggc gaggagggcg tcctcgaccg gggagacctc
     7981 gacgccgctt cggacgacga gatgttcgcg ctcatcgacc aggagctcgg cggagccggc
     8041 tgaggtcccc gccacccacc acgcggagaa cccgccgcgg gcgcacccgc gccgcacatc
     8101 gctcgtacgg cttgcgaagg agttctgggg aagatgtcca acggcagcaa ggacggcagc
     8161 aggggcggca gcggcgacgg cggtaccgag gcgaagctcc gcgactacct caagcgggtc
     8221 accgccgagc tgggccaggc ccggcaccgt ctgcgggagg ccgaggccgc cgccgggcag
     8281 ccgatcgcga tcatcggcat ggcctgccgc tacccgggcg gctgcgattc ccccgagcgg
     8341 ctgtgggagt tggtcgactc gggacgggac gccatcacgc ccttccccgc cgaccgcggc
     8401 tgggacctcg acgcgctcta ccacccggac ccggaccacc gcggcaccag ctacgtcagg
     8461 gagggcgggt tcctgcacga cgccgccgac ttcgacgccg cgttcttcgg catcacccca
     8521 cgcgaggcgc tcggcatgga cccccagcag cgcctgctgc tggagacctc ctgggaggcg
     8581 tgtgaacggg cgggcatcga ccccctcacc ctcaagggcg cgcaggtcgg cgtctacacc
     8641 ggcatcgtca actccggcta cgtctcccgg ctgcgggaga cccccgagtc cgtcgagggc
     8701 tacgtcgtca ccggcaccat ggcgagcgtc gcatcgggcc gcatcgccta caccctcggc
     8761 ctggaaggac cggccgtcag catcgagacc gcctgctcgt cctccctggt cgccctgcac
     8821 ctggccgtgc aggccctgcg ggacggcgag tgctccatgg ccctggcggg cggggtcgcg
     8881 gtgatgccgg tgccggacgc cttcgtggag ttcagccgcc agcgtggcat ggccccggac
     8941 gggcgcatca aggccttcgc cgccgccgcc gacggcacca cctggtccga gggcgccggc
     9001 gtgctgctcg tggaacggct cgccgacgcc cgccgcaacg gccaccccgt gctcgccgtg
     9061 gtccggggct ccgccatcaa ccaggacggc gcgagcaacg gcctgtccgc ccccaacgac
     9121 ctcgcccagg aacgggtgat ccgcgccgcg ctcgccaacg cacggctcac cccggccgac
     9181 gtggacgccg tcgaggcgca cggcaccggg acgacgctgg gcgacccgat cgaggcccag
     9241 gccctgctgg ccgcctatgg cagggaacgc ccgcaggacc ggcccctgtg gctcggttcc
     9301 atcaagtcca acctcggcca ctcaggcccc gccgccggcg tggccggggt gatcaagatg
     9361 gtggaggcga tgcggcacgg cgtcctgccc aggaccctgc acgtggacgc gcccaccccg
     9421 cacgtggact ggtcgtccgg tgccgtccgg ctgctcaccg aacccgtccc gtggaccggt
     9481 cacgacgatc gcccccgcag ggcgggcgtg tccgccttcg gaatcagcgg caccaacgcc
     9541 cacgtcatcc tggaggaggc gccggaggcg gggccggggg agcggaggcc gtccggcgaa
     9601 ccgcacctcg tggcggacgt gctgccgtgg gtggtgtcgg gtcgttcgga cgcggcgttg
     9661 cgggcgcagg cggggcggct cgccgggttc gtcgagcagc gctccgagct gaccgtcggc
     9721 gatgtggcgc gttccctggt ggagacgcgg tcggctctgg agcaccgtgc cgtggttctg
     9781 gccggtgatc gggacgcggc ggtcggggcg ttgcggtcgg tggcggaagg tgtgccggta
     9841 ccgggtgtcg tggccggtgt ggtgtccggg gagcagggcc gggtggtgtt cgtgttcccg
     9901 ggccagggct cgcagtggct cggcatgggt gcggggttgt gggagtcgtc gccggtgttc
     9961 cgggagcggc tccaggagtg tgacgcggcc ctgtctgcgc tggtggactg gtcggtgacc
    10021 gatgtggtgc ggggtgtgcc ggatgcggct tcgctggacg atgtggtggt tgttcaggcg
    10081 tcgttgtggg cggtgatggt gtcgctggct gcgatgtggc gttcggtggg cgtcgagccg
    10141 ggtgcggtga tcggtcattc gcagggggag attgccgctg ctgtggtggc gggcgggttg
    10201 tccgtcgagg acggtgcccg ggtggtcgtg ctgcgggcga gggcgatcgg gcagagcctg
    10261 tcgggccacg gtggcatggt gtcgctggcc gcgggcgcgg accgggtacg ggagttgatc
    10321 gcggcgtggg gtgagcggat ctcgatcgcc tcggtcaacg gcccctcctc gacggtggtt
    10381 tcgggtgagc cggatgcgct ggacgatttg atggccgcct gtgacggcga aggcatacgg
    10441 gcccgtcgta tcgcggtgga ctacgcctcc cactccgcac aggtggagtc gatccgggag
    10501 caggtcaccg aggccctcga ggacatcgaa ccccgtgccg ctgaagtgcc cttctactca
    10561 actgtcttgg gctcggtgat cgacaccggc gatctggacg ccggttattg ggtgacgaac
    10621 ctgcgccagg aggtgcggtt cgacgccacg gtccgtgagc tgctggcgga cggcttcggt
    10681 tacttcgtgg agtgcagtcc ccatccggtc ctgaccgtcg gcatgcagga gaccttcgag
    10741 gaccacgccg actcccaggc tgtcgcgctc ggcaccctcc gccgcgacga aggcggtccg
    10801 gagcgcttac tgacctccct cgccgagggc tacgtgcgcg gcctggccgt cgactggcac
    10861 accctcttcg ccggcaccgg cgcccaacgg atcgagctgc ccacctacgc cttccggcgc
    10921 cggcgctact ggctggagga gcctgccggg gcggcgccga agcaggacgc cggggaactt
    10981 gacgaggtgg acgccgggtt ctgggccgcg gtggacgctg gagccctgga gacgctgacc
    11041 accgagctgg gcgttcccgc cgacgagccg ttcagtgcgc tgctgccggc cctgtcgtcg
    11101 tggcggggcc ggcgtcggga ggagtcgcgg gccgacgggt ggcgctaccg ggtggtgtgg
    11161 cgccccgccc ggttccctgc cgaccggcaa ccgcgggggc attggctcgt cgtcgtaccc
    11221 gagggccgcg cggacgatcc gtgggccgcc ggttccgtgc gcgccctgga acgggcgggc
    11281 gccggagtga cgcggctggt cgtggacgcg gtgggcgccg atcgcgaccg cctcgcgcat
    11341 gtgctgcgtg aggcgttcac cgagggctcc ggcgcaggct ccggtgagac gccgccgggc
    11401 ggggtgctgt ccctgctcgc cctggacgac gccccgcatc ccgcgtaccc ggccgtcccc
    11461 tcgggactcg ccgcgaccgt gacgctcgtg caggcgatgg tccaggcggg tgaggggatg
    11521 cccgcaccgc cccggctgtg gtgcgccacg cggggggccg tgtccaccgg cgcgtccgac
    11581 ccgctggcca gtccggcgca ggcccacgcc tggggtctgg gccgcgtcgc ggcgctggag
    11641 cacccgctgc tgtggggcgg tctcgtcgac ctgcccgcgg acgccggtga caccgaggtg
    11701 gcccggctgg cggccgtgct ccgcgcgccc gccgaggagg accacctggc cgtgcgcggc
    11761 gacggcgtgc acgtccgccg tctggtgcgg gcgccggccg aggcggttcc cgcggtgcgc
    11821 gagtggcggc cgcgcggcag cgtcctggtc accggcggga ccggaggcat cggcgggcac
    11881 ctggcacgtc gtctggcaca gacgggcgcc gagcacctgg tgctggtcag ccggagcggc
    11941 cccgaggcgc ccggcgccac ggaactggcg gaggagctga ccgcggccgg cgcgaaggtg
    12001 tccctggtgg cgtgcgacgt cgccgaccgg gacgcgctgg ccgccgtact cgcgtccgtc
    12061 cccgccgacc agccgctgac ggccgtcgtc cacgccgccg ccgtgctgga cgacggagtg
    12121 atcgaatcgc tggaccccga gcggatggaa cgcgtgctgc gggtgaaggc gcagggtgcg
    12181 ctccacctgg acgagctgac ccgggacgcg gatctgtcgg cgttcgtgct ctgctcgtcg
    12241 ttcggtgcca ccttcggtct cccggcgctc ggcaactacg cgcccggcaa cgccttcctc
    12301 gacgccctcg ccgagaggcg ccgggcgcag gggctgcccg cgacctccgt ggcctggggc
    12361 acctgggcgg ggaccgggat ggcggccggg gacgtcggcg cccgtggccg tctggagggc
    12421 atccacgaga tggatccgga accggcctcc gccgccctgg gacggatcct cgaccgtgac
    12481 gagaccacgg cggtcctcat cgacctgcgc tgggagcgct tcgcccccgt cttccacgcc
    12541 aagcggccca ccgccctgtt ctccgagatc cccgaggccg tcagggcact ggcccggggc
    12601 gccggggacg gggacgcgga cccggccacg gccgacgagg cggccgacgg actgcgggcc
    12661 agactcgccg gtgtcccgcg ggccgagcag gagcgcgaac tgctggaact ggtccgctcc
    12721 cacgcgggag tggtcatggg ccacgtcacc ctcaccggga acgcgcgcga cgccgtcgca
    12781 cccgaccgtc ccttccgcga cctggggttc gactccctga tggccgtgga gctgcgcaac
    12841 cgggtcggcg ccgccaccgg tgtcgccctg ccggccacgc tggtcttcga ccacccgacc
    12901 ccggaggcgg tggcccgtca tctgcggcag gagatgggtc tgggagacgc cgacggcatt
    12961 ccgcccggct tccccgagct ggaacgcctc gaggccgcgc tcgccgccgc gcctgccgac
    13021 gacgaggccc gggcccgcct ggccaaacgc ctggaacggc tgctgtggac ggtgagcggg
    13081 gacgacctcg cgacgacgcc cggagagggc tccggggacc gcgagttctc caccgtcagc
    13141 aacgacgaga tgttcgacct catcgaccgc gaactggggg cctagccgac atgaccaccg
    13201 acgagcagaa actccgggaa tacctcaaca aggtcatgac cgacctgcgc cgcacgcagc
    13261 gccgcctgcg ctcggtcgag gaacgggacc acgagccggt cgccgtcgtc ggcatggcct
    13321 gccgctaccc cggcggcacg gagtcccccg aggacctgtg gcggctcgtc gagggcggcg
    13381 gtgacgccat ctccggtttc cccacggacc gtggttggga cctggcgagc ctgcggctca
    13441 cggacccgga gggcagggag ctggcgcccg agggcggctt cgtggccggg gcggccgcct
    13501 tcgacgccgg actgttcggc atctcgccgc gcgaggccct ggcgatggac ccgcagcagc
    13561 gactggtcct ggagtgctcc tacgaggcgt tcgagcgtgc gggcatcgac ccgttctcgc
    13621 tgaagggcag cgacaccggc gtcttcgtcg gtgcctccta caccggttac ggcgccgacg
    13681 tggagcgcat cccggacggt ctcgagggct acaccatgac cgggtccgcg aacagcgtcg
    13741 tgtccgggcg ggtcgcctac accttcggcc tggaagggcc cgcggtgacc atcgacacgg
    13801 cgtgttcctc ctccttggtg gcgctgcact gggcggtgca gtcgctgcgg gcgggggaga
    13861 cctccctggc gctggcgggc ggggccatgg tgatgccgag cccgatggag ttcgtggagt
    13921 tcagcaggca gcggatcctg gccgcggacg cccgctgcaa ggcgttcgcc gaggccgcgg
    13981 acggcaccgg cttctccgag ggcgccggtc tcgtcctgct ggaacggctg agcgacgccc
    14041 ggcgccacgg ccaccgggtc ctcgctgtcg tccggggctc ggccgtcaac caggacggtg
    14101 cgagcaacgg cctcaccgcc cccaacggcc cttcccagcg acgcgtcatc gaggccgccc
    14161 tcgccaacgc ccggctcgct ccggcggacg tggacgccgt ggaggcgcac ggcaccggca
    14221 ccaccctggg cgaccccatc gaggcccagg ccctgctcgc cgtctacggc aaggagcgtc
    14281 cggccgaaca cccgctgtgg ctgggctcgg tgaagtccaa catcggccac acccaggccg
    14341 ccgcgggcat cgccggcgtg atcaagaccg tcgaggctct gcgccaccgc tcgctgcccc
    14401 gcaccctgca cgtggacgcc ccgaccccac aggtcgactg gtccccggga acggtgcgcc
    14461 tgctgaccga ggcccgtccg tgggacactc cggggggccg cgcgcgccgc gccgccgtct
    14521 ccgcgttcgg catcagcggc accaacgccc acgtcatcct ggaggaggca ccggaggaca
    14581 cggggactcc cggcaccgac gggaccggcg cgacgggcgt cggcgccacc acgaccgggg
    14641 agcacccggt cggcctggtc ggcgacgtcg tcccctggcc cctgtccggt cggacgacgg
    14701 cagccctgca cgcccaggcc gcccgcctct ccgcctacct ggacgaccac cccggcacgt
    14761 ccccgctcga cgtgggagcc accctggccc tctcccgggg cgctctcgac caccgtgcgg
    14821 tcctgctggc gaccgacgcg ggaagcatcc acaccgcgct gaccgctctg ggcgaaggcg
    14881 ttcccacggc cgacgtagtg cccggcacgg tgctgtccgg ggcgccgcgg gtggtgttcg
    14941 tgttcccggg gcaggggtcc cagtggctcg ggatgggggc ggggttgtgg gagtcctctc
    15001 cggtgttccg ggagcggctt caggagtgtg acgcggcgct gtcttcgttg gtggactggt
    15061 cggtgaccga ggtcgtccgg ggtctgccga cggctgcctc tcttgacgat gtggtggttg
    15121 ttcaggcgtc gttgtgggcg gtgatggtgt cgctggcggc ggtgtggcgt tcggtgggca
    15181 tcgagccggg ggcggtgatc gggcattcgc agggggagat cgctgctgct gtggtggcgg
    15241 gcgctctgtc ggtgcaggac ggtgcccggg tggtcgtgtt gcgggcgagg gcgatcgcgc
    15301 ggagcctgtc cggtcatggt ggcatggtgt cggtggccgc gggtgcggac cgggtacggg
    15361 agttgatcgc gggctggggt gagcggatct cgatcgcctc ggtcaacggc ccttcttcga
    15421 cggtggtttc gggtgagccg gtggctttgg acgatttgat ggccgcctgt gacggcgaag
    15481 ggatacgggc gcgtcgtatc gcggtggatt acgcctccca ctccgcgcag gtggagttga
    15541 tccgggagca ggtcatcgag gccctcgcgg acattgaacc ccgtgccgct gaagtgccct
    15601 tctactccac tgtcttgggc tcggtgatcg acaccggcga tctggacgcc ggttattggg
    15661 tgacgaacct gcgtcaggag gtgcggttcg acgccacggt ccgtgagttg ctggcggacg
    15721 gcttcggcta tttcgtggaa tgcagtcctc accccgttct gaccgtcggc atgcaggaga
    15781 cgttcgacga cgtcgcggac gcccaggctg tcgcgctcgg caccctccgc cgcgacgaag
    15841 gcggcccgga gcgcttcttg acctccctcg ccgagggcta cgtccgcggc ctggccgtcg
    15901 actggcacac cctcttcgcc ggcaccggcg ccgaccgccg gctcgacctt ccctcgtacg
    15961 ccttccagcg gcagcggtac tggctggagt ccggccccgc cggggccggt gacccggccg
    16021 ggctcgggct cgcggacgcg ggacatccgc tgctgggcgc ggccgtcgag gtggcgggcg
    16081 gcgaccaact gctgctgacc gggcggctgt cgctccacgc ccacccctgg ctggccgacc
    16141 acgccgtgca gggcacaccg gtgctgaccg gtgccgcgtt cgcggagctc gccctgcacg
    16201 ccggtgagcg ggccggggcc gaggtcgtcg agagcctgac cgtggaggcg ccgctggtgg
    16261 tgccggagag cggcggggtg caggtccagc tgtccgtggg cgcgccggac gaggacggcg
    16321 cgcgtgaact gggcgtccac gcacggccgg ggacgcagga ggacgggacg ccgtgggtgc
    16381 ggtacgccac cgcccggctg gttcccgacg gcgcccgacg gaccggggct gccgacgatg
    16441 ccgggaccgt cgagaggctc gcgcagtggc cgcccccggg ggcccagccg gtcagcgtcg
    16501 ccaacttcca ccagcgcgcg gccgacgccg gacagggcta cggcccggcg ttccgcgggc
    16561 tgcgcgcggt gtggcggcag ggccgtgaga tgtacgccga ggtggccctg ccgggcgatc
    16621 aggagcgaca ggccgccggg tacgggatcc acccggcgct gctcgacgcg gcgttgcagc
    16681 cggcccggct ggaggagcgc tccggagtgc tgtggaccga ctggtcgggc gtgtcgctgc
    16741 gcgcgatggg agcgaccgag ctgcgggtgc acgtaaggcc ttcggacgac ggcgccgtca
    16801 ccgtgaccct cggcgacgcg tcaggccgcc cggtcggcac cgtggaggcg gtggccgcgc
    16861 gcgcggtggc ccccgaggaa ctgcgccgtg gcgcggacgg cgtccgggac gcgctgtacc
    16921 gggtggaatg gacgccggtg ccggcgcccg ggcagaccgc cgactgggtg gtgctgggcg
    16981 acgacccgct cggggtgacc gacgtgctgg aggaggcggg cgcgtacccg cagacgtacg
    17041 acgacctgga cgcgctggcc ggtgccgtgg acgcgggact gccgctgccg gagctgaccg
    17101 tggtgtccca cggtggcgtg gcgcccgcga aggacggtgc cgtggcgcgg cacgccctgg
    17161 aggcggtcac gggcctgctg gcggtcgtgc agcgctggct cgccgacgag cggttcgccg
    17221 gagcgcggct gctggtggtg accaggggcg cggtcgcggc cggccccggg gacggcgcgg
    17281 tggacctggc gcacgccgcc gcgtggggcc tgctccgctc cgcgacggcc gcccacccgg
    17341 gccggttcgg gctgctggat ctggacgggg acgacggttc gctggcggtc ctgccggacg
    17401 ccgtgcccgc cgtcgtcgcc tcgggcgagc ccgagacggc cctgcgcgcg ggtgtggtcc
    17461 tggtgcccag gatccgcccg gcggccaccg cgcccgccgc ggcacgggcc gtctgggacc
    17521 ccgacggcac cgtgctgatc accggcggta ccggcgcgct cggccgggtc ctcgcccgcc
    17581 acctggtcaa gcagcacggt gtgcgccacc tgctgctggt gagccgccgc ggccgcgacg
    17641 cggacggcgc cgaggccctg gaacgcgaac tgtcctcgct cggggcgacg gtgtccgtgg
    17701 aggcgtgcga cgccgcggac cgcgaggcgc tggcgcgggt gctggccgcc gttcccgccg
    17761 accggcccct gacggccgtc ctgcacgccg ccggggcgct cgccgaccgg cccctggagg
    17821 ccctgacagc acaggacgtg gagcacgtct tcacgcccaa ggtgacggcg gcggcgaacc
    17881 tgcacgaact cacccgggag tccgacctgg ccgcgttcgt gctgttctcc tccgcgtccg
    17941 gtgtgctcgg cagcctcgcc cagccgaact acgccgccgc gaacgccttc ctcgacgccc
    18001 tcgccgcgca ccgcagggcg gcgggcctgg ccggtctgtc cctggcctgg gggctgtggg
    18061 ccggggcgag cgagatggcg ggaggcgcgg acacggaccg gttcgcccgc gcgggcatcc
    18121 tggcgctgtc cccggacgag ggcaccgccc tgttcgacgc cgcgtcggcc accgacgagg
    18181 cgctgctggt gcccgtgctc ctggacacgg ccgcgctgcg ctcccgtgcc gccgacggca
    18241 ccctgtccgg gatgctgcgc ggcttggtga aggcggcgcc aggcaagcgg gccgcgtccg
    18301 cacccggcac cgggccgcag gagccggact gggcggcacg gctcgccggc ctcacccggg
    18361 acgagcagct gcaccggctg gtggagctga cccgcgccca cgtggcgtcg gtcctcggcc
    18421 acgggacccc ggaggccatc gagcccgacc gtccgttcaa ggagatcggc ttcgactcgc
    18481 tgaccgcgct ggagctgcgc aaccgcctcg gtgcggccac cggcctcacc ttgcccgcca
    18541 ccctcgtctt cgaccacccg acgctgaatg ccaccgccgc cctcctcctc gacctgctcg
    18601 cgcccgccgc cacgaccgcg ccgccacccg ccctggccga actggaccgg ctggaggagg
    18661 cactggccgc cgtccccgac gacgacaccg cgacccgcgc ccgggtgcgg gaaaggctcc
    18721 aggccctgct ggccgggtgg aacggcgcgc cccggccgtc cgacggtggc gacgaggaac
    18781 tggacgacgc caccgacagc gagctgttcg cactgctcga cgacgagctg gacacgccgt
    18841 gaccacggcc tgccttccac acagcgaccc gaggacctcg gccatggatg ggtgtgacag
    18901 ccgatgaaca gcgaagacaa gctgcgggac tacctgaagc gggccaccgc cgacctgcgc
    18961 agggcgcgcc gccgcatcca ggagctggag gagcccgaac cggtcgccgt ggtgagcatg
    19021 gcctgccgct accccggctc cgccgacacc ccggaggccc tgtgggagct gctggcctcc
    19081 ggcgtcgacg ccatctcccc gttccccgtc gaccggggct gggacctgga ggccctgtac
    19141 gacccggacc cggacgcgga gggccgcaac tacgtgcggg agagcgggtt cctgcacgac
    19201 gcgggcgagt tcgacgccga cttcttcggc atcaacgccc gcgaggcgct gatcatggac
    19261 ccgcagcagc ggctgctgct ggagacgtcg tgggagctgt tcgaacgggc gggcatcgac
    19321 ccgcggtccg tccggggcag ccgcacgggc gtcttcgtgg gcgccgccac cgtcgactac
    19381 gtgacgggcc accagtacgt gccggaaggc ctggagggct acaccggcgt cggctcgttc
    19441 gccagcgtca tctccggccg ggtcgcctac tccttcggca tggagggacc cgcgctcacc
    19501 gtcgacacgg cctgctcctc ctccctggtc gccctgcacc tggccgtcag gtcgctgcgg
    19561 cagggcgagt gcgccatggc gctcgccggg ggcgtcgcac tgatgccgac gccgcagggg
    19621 ttcatcgcct tcagcaggca gcgcgccctg gcgcccgacg gccgctgcaa ggccttcgcc
    19681 gacgccgccg acggcttcgg gccgtccgag ggcgccggga tgctgctgct ggaacgcctg
    19741 tcggacgcgc ggcgcaacgg ccacccggtg ctcgccctga tccgcggcac cgccgtcaac
    19801 caggacggcg ccagcaacgg cctcaccgcc cccaacggcc cctcccagga gcgggtcgtg
    19861 cgcgacgccc tcgccgacgc ccggctgacg cccgccgagg tggacgccgt cgaggcgcac
    19921 ggcaccggga ccaccctcgg cgaccccatc gaggcccgcg ccctgctcac cacgtacggc
    19981 agggaccggg acccggcacg ccccctgtgg ctcggctcgg tcaagtccaa cttcgggcac
    20041 accgcgcacg ccgcgggcgc ggccggggtc atgaagatgg tcctggcgct gcgcaacgaa
    20101 ctgctgccgc gcaccctcca cgtggaccgc ccctccacgc acgtcgactg gacctccggc
    20161 gcggtcgcgc tgctcaccga acccgtggcc tggaagcgca acggccgccc gcgccgcgcc
    20221 ggcgtgtccg cgttcggcat cagcggcacc aacgcccacg tgatcgtgga ggaggccccg
    20281 cagcccgagg acggcgccgc gcccccggac ggcggtggcg ggagcggcgc ttcggcccgc
    20341 cccccgctcg cgctgcccgt cgtgccctgg gtgctgtccg ccaggacgcc ggccgccctc
    20401 gccgcgcagg ccgagcgcct cgccgccttc gcggaacgcc gcggcgaggt gcccgacacc
    20461 gacatcggcc ggtccctggc caccggacgc gccgccctgg aacaccgcgc cgtggtcctc
    20521 gcgggcgacc gcgcccgcgc cctcgccggc ctggaagccg tgcgccgcgg cgagcccacc
    20581 gccggggtgg tcaccggcac cgcgcggccc ggtgcggccc gcgtggcgtt cgtcttcccc
    20641 ggccaggggt cccagtggca gggcatggcg gccgggctgc tggagtcgtc cccggtgttc
    20701 gcgcagcggc tcaccgcctg cgacgccgcc ctgcgcccgt ggaccggctg ctcggtgatc
    20761 gacgccgtcc gcggcggcga gggcgcggcg tcgctggacg acgtggtggt cgtccagtcg
    20821 gcgctgtggg ccgtcatggt gtcgctggcc gcgctgtggc gctccgccgg agtggagccc
    20881 gccgccgtca tcgggcacag ccagggcgag atcgccgccg ccgtggtcgc cggggcgctg
    20941 tccctggagg acggggccag ggtcgtggcg ctgcgcgccc gcgccatcgc cgggggcctg
    21001 tccgggcgcg gcggcatggt gtccgtgccg ctgcccgcgg gacgcgtcgc cgcgcgcctc
    21061 gcccgctggg agggccgcgt cgggatcgcc tccgccaacg ggccgtcctc caccgtggtc
    21121 tcgggcgacc ccgaagccct cgacgagctg ctggccgact gcgaggcgga cggggtgcgg
    21181 gcccgccgca tcgccgtgga ctacgcctcc cactcggccc acgtcgagac gatccgcgac
    21241 gaggtcctca ccgccctgga cgacatccgg ccgcgcggcg gcgccgtccc cttccactcc
    21301 accgtcaccg ccggccccct cgacacggcc gggctcgacg ccgggtactg gtacaccaac
    21361 ctccggcgta ccgtgcgctt cgaggagacc gtgcgcggcc tcctggcggg cggcatccgc
    21421 ttcttcgtcg aatgcagcgc ccacccggtg ctggccgtcg gcctccagga gatcttcgac
    21481 gacgccgggg ccgacgccgt cgcgctcggc tccctgcgcc gcgacgaggg cggcccggag
    21541 cgcttcctca cctcgctcgc cgaggggcac gcacgcggac tgcccgtgga ctgggacgcc
    21601 gtgttcgcgg gcaccggcgc ccgccgcgtt cccgacctgc cgacctaccc gttccagcga
    21661 cggcactact ggctggaggc cgagtaccgc aatgcgggcg acgcgggcga cctcggtctc
    21721 acctccgcgg gacaccccct gctcggggcc gcggtgcggc tcgccgaagg ggaccggctg
    21781 ctgctgaccg ggcggctgtc gctcaagacc cacccctggc tcgccgacca cgccgtgggc
    21841 gggaccgccc tcgtgcccgg caccgcgttc gcggaactcg ccttggaggc cgccgcgcgc
    21901 accggctgcg cgggcgtcgc cgagatgacc ctgcacagcc ccctcaccgt ccccgcacgc
    21961 ggcgccgtcc acgtccaggt ggaggtcgac ggccccgacg acgccggccg gcgcgccctc
    22021 accgtgcacg cccgtcccgg cgacgccgcc gacggcgatc cctggacccg gcacgccacc
    22081 gccttcctcg ccccgcccgg gcccgtcacc gacggcgagg cgctcaccgc gtggcccccg
    22141 cccggcgcgg cgcgcctgga caccgcgggg atgtacgagc cggtcccggg cggcgcctac
    22201 cggttcggcc ccgccttcca ggggctgcgc tccgcgtggc ggctcggcga caccgtctac
    22261 gcggaggccg cgctcccgcc cgaactgcac caggacgccg cccggttcgg cgtccacccg
    22321 gccctcctgg acgccgccct gcacgccatc ggcttcggcg gcttcctcgg cgagggcacc
    22381 cacctgccgt tctcctggca cgacgtcacc ctgcgcgccg tcggtcccgc cgcggtgcgg
    22441 gtgcgggtgc gcgccgccgg gaacgacgcg gtcaccgtca ccctcgccga cgccgagggc
    22501 gcccccgtgg ccacggtcgg gcgcctggtg ttccggcccc tcccggccgg cggcgacgac
    22561 acgggcgacg gcctgcgcga ctcgctgttc cacgtcgact gggcgccgct gcccgtcgac
    22621 gccgccgccc cgtccggcgc gggctgggcc gtgctcggcg gtgacggcca cggtctggtg
    22681 ccggccctgc gcggcgccgg cgtgttcgcc ggcgcccacc gcggcccggc cgagctcgcc
    22741 gccgccgtcg cgtccggcgc gcccgccccc gacgtggcgc tgctgtcctg cccgtccgac
    22801 ccggccaccg tcgccgccga cggcctgccc gccgccgtcc gccgtgccac cgagggcgtg
    22861 ctgcgcgtcg tacaggagtg gctggccgac gaccggttgc gcggggtcgt cctcgccgtg
    22921 gtcacccgcc gtgccgtggc cgcggggccc ggcgaggacg tcgaggacct ggcgcacgcc
    22981 ggcgtgtggg gcctgctgcg ctccgcgcag atggagaacc ccggccggtt cctcctcgtc
    23041 gacctcgacg ggcgcgacga gtccagggcc cgcgccgcgg ccgccgtcag ggccgccctc
    23101 accgccgacg agccccagct cgccctgcgc ctcggcgccg cccgcgtccc ccgcctggcc
    23161 aggaccccgg ccggcgcctt cctcgtcccc ccgcccggcg aggccgcctg gcgcctggac
    23221 accaccggcc ccggcgacct cgaccggctc gcgctgctgc cccacccgca ggcactggcg
    23281 cgcctcacgg acaaccaggt ccgggtctcc gtacgcgccg ccggcgtgaa cttccgcgac
    23341 gtgctggtcg gcctcggcat ggtgccctcc caggaacgtc tgggcagcga gggcgccggg
    23401 gtggtcaccg aggtcggccc cggcgtcacc ggcgtcgccg tcggcgaccg ggtgatgggc
    23461 ctgctgcccg acccgttcgg ccccgtctcc gtcgtcgacc ggcgactggt cacccgcatc
    23521 ccgcgcggct ggaccttcga gcaggccgcc ggtgtgcccg cggcgttcct caccgcctgg
    23581 ttcggcctcg ccgacctcgg cgggctccgc gaggacgaga ccgtgctcgt ccacgccgcg
    23641 accggcggcg tcggcatggc cgccgtgcag ctggcccgct accggggtgc ggaagtgttc
    23701 gcgaccgccg gtgagggaaa gtgggacacc ctgcgccgga tgggcttcga caccggccac
    23761 atcgcctcct ccaggaccct ggacttcgag aagaagttcc acgccgccac cggcggacgc
    23821 ggcgtcgacg tcgtcctcaa ctccctcgcg aacgagttca ccgacgcctc cttacggctg
    23881 ctgccgcgcg gcggccggtt cctggagatg ggcaagaccg acatccgcga cccccacgag
    23941 gtcgccgagc gccaccccgg cgtcgtctac cgcccctacg acctcatcga cgccggcgcc
    24001 gaccgcatcg gtgaaatcct cgacaccctc gtccggctct tcgaacgccg cgtgctgcgg
    24061 ccgctgcccg tccgcacctg ggacgtgcgc cgcgcccccg aggcgttccg gttcatggcc
    24121 caggcccggc acaccggcaa gctcgtcctc accgtccccc gtcccccgga ccccgacggc
    24181 accgtgctcg tcaccggcgg caccggaacc ctcggcggca tcctcgcccg gcacctggtc
    24241 accgcccacg gcgcgcggca cctcctgctg gccggacgcc gcggcccgca ggcacccggc
    24301 gccgacggcc tgcgcgagga cctgctcgca cgcggcgcgc acacggtcac cgtcgccgcc
    24361 tgcgacaccg cggaccgcga ggcgctctcc gacctgctgg cctccgtgcc cgcggaccgc
    24421 ccgctgaccg ccgtcgtgca cgccgcgggc accaccgccg acggcgtcct gtcctccctc
    24481 accccgcagc ggctcgacga tgtgctgcgg cccaaggcgg acgcggcgtt ccacctgcac
    24541 gagctcaccc gggagtcgga cctggccgcg ttcgtcctgt actccgcggg tgccggcgtc
    24601 ctcggcaacc ccggccaggc caactacgcc gccgccaaca ccttcctgga cgccctcgca
    24661 caccaacgcc gtgccgccgg tctccccgcc gtctccctgg cctgggggta ctgggccgag
    24721 accagcgaac tgaccggccg catggacgac tcccacgtgg agcggatgac ccgctccgga
    24781 gtcctgccca tcgacgccgg gcacggcatg cgcctgttcg acgccgcccg ggcggcgggc
    24841 gaggccctcc tcgtgcccac gcggctcgac gtgtcggcgc tgaggacggg cgcctccacg
    24901 gacgtcggcc cggcgatgct gcgcggcctg ctcggcggcc ggcggcaggc accccgccag
    24961 gccgcccggg ccgggaccgc agccgtcgag gcccgctcgc tggaggccag gctcgcggcc
    25021 ctgcccgccg acgagcagcg gctcctgctg gaggacctgg tgcgcggcca cgtcgccgcg
    25081 gtcctgggcg cctccgggcc cgaggccgtc ggcgccggga gggccttcaa ggacatgggc
    25141 ctggactcgc tcaccgccgt ggaactgcgc aaccgcctcg gcgcggccac cggcctcacc
    25201 ctgcccagca ccctcgtctt cgacttcccc tcgccccggg agctcgccgg gcacctgcac
    25261 caggagctcg ccccggacgg ggccgcggcg gccgcggacg gccccgaccc gcaggaggcc
    25321 cgggtgcggg ccctgctcgc caccgtcccg ctggcccgcc tgcgcgccgg cggactgctc
    25381 gacaccctgc tcgggctcgc cgaggagccg gcgcccggca ccaccggacc cgcgccggac
    25441 cggaacgccg gggcgatcgc cgacatggac ctcgaggacc tggtgcgcgc cgccctcggc
    25501 ggcaccgggt cgtgaaccgg ccgcccgcgg cgggccaccg ccgcaccccc ggggaccagg
    25561 aacggcgcgg tgagcgcccg acagagaggg agtgaccgat gacctccacc gaacagatca
    25621 tcgaggccct gcgcgcggcc ctcaccgaca acgaacgact gcgcgagcag aaccggcggc
    25681 tggtcgccgc agcctcggaa ccgctcgccg tcgtcggcat ggcctgccgc ttcccgggcg
    25741 gggccgactc cccggacctg ctgtgggagc gcctggccga cggcagggac atgatgtccc
    25801 cgctgccccg cgaccggggg tgggacctcg acgccctgct cggcaccgcc gacggcggcc
    25861 ccgccgcgtc cgccgcgcgg gagggcgggt tcctggccga cgtctcccgc ttcgacgccg
    25921 agctgttcgg catctcgccc cgtgaagccc tggccatgga cccgcagcag cgggtcatgc
    25981 tggaggtcgc ctgggaggcg ttcgaacact ccggcctgga cccgctgtcc ctcaagggca
    26041 gccccaccgg ggtcttcctc ggcgtgtcct acgccgccta cggctccgac gtcacccacg
    26101 tccccgccga ggtccagggc tactccatga ccggcaacgt caccagcgtc gcctccggtc
    26161 gcatcgccta cacgctcggc ctggagggcc cggccgtgtc cgtcgacacc gcctgctcgt
    26221 cctccctggt cgccctgcac caggcggcgc acgcgctgcg ggccggcgag tgctcgctcg
    26281 cgctcgtcgg cggggtgtcg gtcatgccca cgccggcgct gctcgtggag ttcacccggc
    26341 agcgcggcat ggcgggcgac ggccgcgcca aggcgttcgc ggccgccgcc gacggcaccg
    26401 cctgggccga gggcgccgcg gccgtcgtcg tggaacggct gtccgacgcg cgacgccacg
    26461 gccaccgggt cctcgcgctg gtgcgcggct cggccgtcaa ccaggacggc gccagcaacg
    26521 gcctcaccgc ccccaacggc gccgcacagc gccgggtgat ccgcgccgcg ctggacagcg
    26581 ccggcctcac gccccaggag gtggacgccg tcgaggcgca cggcaccggg acccgcctgg
    26641 gcgaccccat cgaggcccgc gccctgttcg acacctacgg cagggaccgg gacccggcgc
    26701 acccgctgtg gctgggcgcc gtcaagtcca acttcggcca cgccgggacc gcggcgggcc
    26761 tcgccgggct cgtcaagacg gtgttggcga tgcgcgcggg gcggctgccg aggaccctgc
    26821 acgtggacga gcccacccgg gccgtcgact ggtcgtccgg cacggtgcgg ttgctcaccg
    26881 aggacgtcgc ctggacccgc gccggccacc cgcgccgcgc cgggatctcc tcgttcggca
    26941 tcagcggcac caacgcccac gtgatcgtgg aggaggcccc gcaagccccg gacttcccgg
    27001 ccccgggcac cccgcaggcc cgagggctca cggaacctga gggcgcggtg ggcgcggcca
    27061 cggcgggcga cgggacggcg gccgtcacgg aaggaccggg atcggcccgc ggcacgggcg
    27121 cggttcccgg cgcgggccgg gccccggtcc ccgaggcggc ttcggccccc ggcgagggca
    27181 cgggccgccc ggaggcggcc gccgcggccg acaggcacac gtccggctcc ggctccaccc
    27241 ccgccgagac ccccttgccc ctcgccgggc ggaccggggc cgcgctgcgc gcccaggccg
    27301 cccggctcgc cgaccacatc gcccgcagga ccggcgtccc cctcgccgac gtcggcctct
    27361 cgctcgccac cacccgcgcg cggctgcccc ggcgcgccgt cgtggtcgcg gacggccggg
    27421 aggaggccct gcgggccctg cgcgccctcg ccgccggtga gcccgacccg gccgtcacgg
    27481 aaggcgaggc ggagaccgag aaccggcccg cgttcctgtt caccggccaa ggcgcccagc
    27541 gccccggcat gggcgcgggc ctgtacgccg cgttcccggt gttcgccgcg gcgttcgacg
    27601 agacctgcgg gtccctggac cggcacctgg agcactcgct gcgcgaggtc gtcctcgccg
    27661 cgccgggcac ccgaggagcc gccctgctcg acaccaccgc ctacacccag cccgccacct
    27721 tcgccctcca ggtcgccctc caccggctgt gggagtcctg gggcgccgcc ccgcgcttcc
    27781 tcatcggcca ctccgtcggg gagatatccg ccgcgcacgt ctccggtgtc ctctccctgg
    27841 acgacgcggc cgccctggtc accgcgcgcg gcgccctgat gcaggccctg ccgcccggcg
    27901 gcgccatgta cgccgtgcag gccacgccgg acgaactcgc gccccacctg gcgggccgcg
    27961 aggccgaggt gtccctcgcg gccgtcaacg ggccccgctc cgccgtgctg tccggcgacg
    28021 ccgaggccgt ggccggggtc gccgcgcact gggcggagcg cggtcgcagg accaagaggc
    28081 tgcgcgtcgg ccacgccttc cactcggccc gtatggaacc catgctcgac gccttccgcg
    28141 aggtcgcggc cgccctctcc taccggcagc ccaccgtgcc cgtgatctcc aacgtcaccg
    28201 gccgggccgc cgcccccggt gaactggccg acccgggcta ctgggtgcgg cacgtgcgcg
    28261 gcaccgtccg cttcctcgac gggatgcgcg cgctcgccga cgagcacgtc accgcctacg
    28321 tcgagctggg gcccgacgcc gtcctcaccg ccatggcgcg cgagtgcctg ggcggccgcg
    28381 ccgcggcccg cgtcctggcc cccaccctgc gccgtgaccg gccggagacg cgcaccgccc
    28441 tcaccgcggt cgccgccgtg cacgcccacg gggtgccgct cgactgggag gcggtgttct
    28501 ccgggcgcgg ggcgcgccgc accgacctgc ccacgtacgc gttccagggc aggcgctact
    28561 ggctgaccag cgcacccgac gcccacgccg gtgacgtcgt gccgaccctg ctggcccagg
    28621 ccccgtcccg ggaccgggac ccggccgccg ccggggacgg tacgccgccg cccgcggacg
    28681 tgggggagcg gtgggccgac cggctgcccg ccctggacga ggaggccagg accgccctgc
    28741 tgacgggact ggtccgccgg cacgtcgccg cggtgctcgg ccacacctcc ccggaggagg
    28801 tcctcgtcgc ccgcgacttc ggcgagctgg gtctcgactc catgccggcc gccgacctgc
    28861 tgacgcggct ccaggcggcc accgggctcg acctgccggc caccgcagtc ctcgaccacc
    28921 ccagctgcga acgcctcgcg gcgcatctcg ccgaccgtct cgccgacggc gtccctgtcg
    28981 ccgcgccccc cgcccgcccg gacgggctcg ccgggctgtt cctgcgggcc tgccgcgagg
    29041 gccgggcgcg cgaggcccac gagctgaccg ccggcctcgc ggcgttccgg tcctcgttca
    29101 ccgactccgc cgggctcgac cgggcgccgc gcaccgcctg gctgtgcgac ggcccggacg
    29161 agccggtgct gctgtgcttc ccctcgttcg tctggcagca gaacttctac acctacgcca
    29221 agctggcctc cggcttccgc agcggtcgcg ccgtcgccac gatcgggctg ccgggcttcg
    29281 aggagggcga gcccctgccg gcctccgtgg acgccctcgc cgaggcgctg gccgacgcgg
    29341 cccggcgggc ggccgcgggc cggacgttcg ccctgctcgg gcactccggc ggcggcaacg
    29401 tcgccgcggt ggtcgccgcc cggctggagc ggcgcggcac cccgcccggg gcgctggtgc
    29461 tgctcgacac cccggcatgg ggcggcgggc acggcctcgg cggcgagcgg tggggcgacg
    29521 ccgtgcagcg cgccctcgtc gagcgggccg ccctggtggc gcgggccgcg gacggcgccg
    29581 cggaggcgtg gatcaccgca cgggcccggt acgccgggtt cgactacgca gtcccccacc
    29641 tcggcacccc cacgctgctc gtgcgcgcca ccgaacccct cccggcgcag ggcggcccgg
    29701 accccgccga cgacggctgg cgggtggcct gggcgctgcc gcacaccgtg gccgacgcgc
    29761 ccggcgacca cttctcgatg ctggaggccg accacgcggc caagacggca caggccgtcg
    29821 acgactggct gcgcggcccc cggtgagccc ggcggcgccc ccggacgccc cggatcctct
    29881 tcggcccgac ggcgtccgac cccgggccgg gacgcaaccg ggccggcccc cttccccgca
    29941 ccacggagca gaaacggaca cacggcatga ccccctggga ccgtgcagcc ggaccatggc
    30001 tgacgcgcta caccccgccc cggcccgctg gtggccgcat ccagctcgtc tgcctgccgc
    30061 acgccggcgg ctcggccacc ttcttccagc cgctcgccag ggcgttcgag gcgctgccag
    30121 acgccccctt cgaggtgctc gcggtccagt acccgggccg tcaggaacgg cgcgcggaac
    30181 cgctcctcga cgacctggcg gccctggcgg accgggtggc cgaggccctg cggcacgccg
    30241 gggacgcccc gctcgtgctg ttcgggcaca gcatgggagc gctcgtggcc tgggaggccg
    30301 cacgcaggct gtgccggccc ggggacacac ccccggcggg gctggtcgtc tccggccgcg
    30361 gcgcgccctc cctccaccgc gacgtgcggc tgcacctgcg caccgacgcc gaactggtcg
    30421 cggacctgcg ctacctcagc ggcaccgcgt ccgacctgct gaccgacccg gatgtcctcg
    30481 gcatggtcct gcccgtgctg cgcggcgact acaaggccgt cgacggttac cgctacgagc
    30541 ccgggtcccc gctgagctgc cccgtcgccg tctttctcgg cgaccgcgac ccgtgggcca
    30601 ggcagcggga ggcgcgcggc tggcaggagg agaccaccgg accggtgacg ttccgcacct
    30661 tccccggcga ccacttctac ctcaccgcgc ggtgggacgc ggtggccctc gcggtcgcgg
    30721 agtccctggc cggcgtcacg gccggctgac ggcgcgcacg cagacgatcg tcttccccga
    30781 aaggaacgtg agaggaacga tgtccgagac gacacgggcg gtggtcctgg gcgcgggcat
    30841 ggcgggcatg ctggccgcca ccacgctggc gcggcacgtc gacgcggtga ccgtgctcga
    30901 ccgcgaccgg ctgcccggcg acgccgaccc ccgccgcggc gtgccgcagg cccggcacac
    30961 ccacgtgctg tggtcgggcg gcgcgcgggt catcgagtca ctgctgcccg gcaccacgga
    31021 ccggctcctc gacgcgggag cgcaccgcat cgggctcccc gaggacctgg tgtcgctgac
    31081 cgcgtacggc tggcaacggc gcttccccga gacccagttc atgatcgccg ccagccgctc
    31141 gctgctggac tggaccgtgc gcgaccgtgc cggggccgac ccacggatca ccgtgaccgg
    31201 cgacaccgac atcatcgggc tgcggggcga cgcgtcggcg gtcaccggcg tcacctacaa
    31261 gccgcgccgg gagggcaccg tgtcggtgct cgacgccgac gtcgtggtgg acgccacggg
    31321 ccggggctcc ccggtgaagc gctggctcgc cgcgctcggc ctgcccccgg tgcaggagga
    31381 cgtcatcgac tccggcatgg cgtacgccac ccggatcttc cgggcgcccc cgggcgcgcg
    31441 gaagaagttc ccgctggtca gcgtgtacgc cgatcaccgc gccggggtgc cggggcgcaa
    31501 cggcatcctg ctgcccatcg aggacggccg ctggatggtc acgctctccg gcacccgcgg
    31561 cggcgagccg ccgaccaccg aggagggctt caccgcctac ctgcgcaccc tgcgccaccc
    31621 cctgatcgcc gacctcgtcg agcgcgcgga gccgctgacg ggtgtccagg cgtcccgttc
    31681 gaccgcgaac cggcgcctgt actacgaccg gctcgtggaa tggcccgacg gactggtggt
    31741 cctgggcgac gcggtcgccg cgttcaaccc cgtctacggg cacgggatga gcgccgcggc
    31801 gctcagcgcg gcggccctcg gcgccaccct ggccgaacgc ggactgcggc cgggcaccgc
    31861 ccgggccgtg cagcgggccg tcggtgcggt ggtggacacc ccgtggtcgc tgggcacctc
    31921 ccaggacatc tgctacccgg acgtgctcgc ccgcacggac gacccgcgcc tgaccaggca
    31981 cgcggcgcag cggcgcgccc aggccgacct gatcggcacg gcggccctcg cggacgccgc
    32041 ggtgtgcgcg gccgcgatgc gcgtcaacac cctgtcgggc gtcgccgacg acgccttcca
    32101 ggcaccggag gtgcgcgcgg cactggccgg ggcggccgcg ctcgacctgc ccgacgggcc
    32161 gacgctgagc gacgacgagt acgcggcggc gcggacggcg gtgcccgcgg gccactgaaa
    32221 cgggcggatc cgggctccgg cagcgcgcca ccgctgtcgc gagcttcccg tttcctcgtt
    32281 cagtcattac agtgatgact gaaacggcta tagctcacta tgagctacag gaggtgctgc
    32341 agcatgtcgt cggacgacgc cgggagacag caggatcccg acgcggagcg gctccgcgcc
    32401 tggatggagc gggtgacggc atggttcatg ctgcaggccg gctggccgcc gatcatgggc
    32461 aggaccatgg cgtggctgat gatcagcgag ccgccggagc agacggccgc gcagatcgcc
    32521 gaagccgtgc aggccagccg cgcgtccctg accaccaccc tccggctgct caccgaggcc
    32581 cgcatggtgc aggccgtcac ccgcgccggt gagcgggcca cgtactaccg gatcacggag
    32641 gacgcctggt cgggcgtcct caagcggcgc ctggagagca tgacgtcctt cgcggacatc
    32701 acggcagagg gcctgcggct gttcccggag ggtgaggtgc gcgcggccag gatgcgcgag
    32761 gcccaccgca tgttcacctg gctgaactcc gaggccgaac ccatgtggaa gcgctgggac
    32821 gccgtcaacc gcggtgaccg ggcggacgat ccgaacgacg aggacgggat gccgttatga
    32881 gtgatgtgca gagccgcaaa tggtgggccc tcggggccat cggcttaagc ctgctggcga
    32941 tcggtgtcga cgcgaccatc ctcaacgtgg cgctccccac ggtgagcgcc gacctcgacg
    33001 cgtccaccag ccagctccag tggatcgtcg acgccttcac cctggtcctg gcggccgtgc
    33061 tgctgcccgc cggcctgctg ggtgacaagt tcggccgcaa gaagttcctg gtcgccgcgc
    33121 tcctgctgtt cggcgtcgcc tccctgctgt gcgcctactg caccagctca gggcagctca
    33181 tcgccgcccg ggccgtgctc ggcctggccg cggccttcat cgtgccgctg tccacctccg
    33241 tcctgctgaa catcttcgag accgaggcgg agcgtacgaa ggccatcgcc gtcatcgccg
    33301 tctcccagat gctcggcctg ccgctcggcc ccatcatcgg cggcgccctg ctcaaccact
    33361 tctggtgggg ctcggtcttc ctcatcaacg tgcccctggt gctgctcggc gtcctcgccg
    33421 tcgcgaagct cgtgcccgag tcccgcagcg ccgagcgcgt gaccatcgac ctgggcggcg
    33481 tggtgctctc cagcgccggt ctcaccgcgc tcacctacgg cgccatcgag gcgggcgaga
    33541 agggctggga cagcaccgag acggccgtcg cgctgctcgc cggcgccgtg ctgaccggcc
    33601 tgttcgtcct gtgggagctg cgcgtcaccg cggccggcaa ggacccgctg gtcgacctcg
    33661 gcctcttccg cggcaggggc ttcgtgtggg gctccgtcct gagcaccatc gtcagcttcg
    33721 cgatgttcgg cctgatgttc gccctgccgc agtacttcca ggcggtgctg ggatccgacg
    33781 ccctcggcac cggcctgcgg ctgctgccgc tcatcggcgg cctgctcgtc ggggccagcg
    33841 tcatcaacaa gatgccggcg cagctgggcc cgcgcgccgt ccccgccctg ggcttcctgc
    33901 tggtgagcgt gggcctgttc atgggcaccg ccaccgagac cgactccggc tacggctacg
    33961 tcgcgatctg gctggtcgtc atcggcgccg gcctcggcct ggcgatgacc cgctccatgg
    34021 cggcggccct caactccctg tccaaggagc gcagcggcgt cggctcggcc gtggtgcagg
    34081 cgctccgtca ggtcggcggc gcgatcggtg tcgcggtgct cggcgccgtc gccaactccg
    34141 cctaccgcgg caacctcgac ctccccggca ccccggacga gatcgcggac gccgccgggc
    34201 gcagcgtctc caccggcgtg gccgtcgccg ccaagctccg tgacccggcg atgctcgagg
    34261 aggtccggga cgcgttcatg ggcgccatgc acaccctgct gtacgtctgc tccggcatcg
    34321 ccctggtcgc cgcgctgctc gccctcgcct tcatgcccaa gcaggccgcc gtcccggcca
    34381 aggacaccga gcaggagagc gcggaaggga agcggatcac cggctcggtc gcctgaggaa
    34441 tcccccgtcc caggcgaccg tgaaaaggcc gcggcaccac cggctcacgc cgagggtgcc
    34501 gcggccgccc catacccgcc gcaccgcccg ttcccggccg cacccctaac caccgccccc
    34561 gacccctaac cccggcccgc ggcggggccc cggcgggtac ggggcgtccc ggcagattag
    34621 gggttctggc ccctcgtcga cggtccctac agtcgcagac ggcggtcagt cactcctcac
    34681 gccagaatcg gggacctcgt ggaagccata gtcagcgccg tactctccga cgatgcccgg
    34741 cccgaggaca tcgcggccct cccgctgccc gagtcgtacc gcggggcggt gatccgcaag
    34801 gaggacgcca cgatgttcga ggggctcgcc acccgggaca aggacccggc caaggccctg
    34861 cgcgtggagg aggtgccgac cccgcagccg ggtcccggag aggcgctgat cgcggtcatg
    34921 gccagcgcga tcaactacaa caccgtgtgg agcgccatct tcgagccgct ccccacgttc
    34981 acgttcctcg agcgctacgc ccgctccggc gaccccgacg ccgtccggca cgaccagccg
    35041 taccacgtgc tcggctcgga cctcgcgggc gtggtgctgc gcaccggccc cggcgtgcgc
    35101 ggctggaagc cgggggaccg ggtggtggcc cactgcctgt ccatcgagct ccaggcgccg
    35161 gacggccacg acgacaccat gctcgacccc gagcagcgca tctggggctt cgagaccaac
    35221 ttcggcggcc tggccgagct gtccctggtg aaggtcaacc agctcatgcc catgccgggc
    35281 cacctcacct gggaggaggc cgcggcgtcc ggactggtga actccaccgc ctaccggcag
    35341 ctggtctcgc gcaatggcgc ccggatgaag cagggcgaca cggtcctcat ctggggcgcc
    35401 gccggcgggc tcggctccta cgccacccag atcgcgctca acggcggtgc cgttcccgtg
    35461 tgtgtggtct ccgggcagcg caaggccgag ctggtgcgct ccatgggcgc cgaactggtc
    35521 atcgaccggg cgcaggaggg gtaccggttc tggaaggacg agtccacacc ggacccccgg
    35581 gagtggaagc gtttcggcgc caggatcagg aaactgacgg gcggtgagga cccggacgtc
    35641 gtcgtggagc accccggccg ggagacgttc ggcgccagcg tgtacgtgac caggcgcggc
    35701 ggctccgtcg tgacgtgcgc ctccacctcc ggataccggc acgagtacga caaccgctac
    35761 ctgtggatgt ccctcaagcg catcatcggc agccacttcg ccaactaccg tgaggcgtgg
    35821 gaggccaacc gtctcatcgc caagggcatg atccacccca cgctctccac cgtgtacccg
    35881 ctctccgcgg tgggcaccgc cacccaggac gtgcaccgca accgccactc cggaaaggtc
    35941 ggcgtgctgt gcctggcgcc ggagcccggc ctcggagtac gcaacggtga actgcgcgag
    36001 cggcacctgc ccgccatcaa ccgcttccgc gctccgaccg actgacgccc gccgaccgca
    36061 cgagcgccgc agggcagccc gcggacgacg gcgcggcacc accgctcctc acggtggtgc
    36121 cgcgccgtcc gcgtcccgct ccaccggcgt caaccggcgt cggccgccgc ctccttcgcg
    36181 aacgccgcca cgtactcgtc gatcgtgtcc gccaccgacg cctggtggtc gttgaggtag
    36241 aagtgcccgc ccgggaagac gcggaagcgg aagccgcccg tggtgtgccg acgccacgcc
    36301 tgcgcctcct ccggcgtcac ccgcgggtcc gcgtcgcccg tgaccacccc gacggggcag
    36361 cgcaacagcg gctcgggcgc cggctcgtgc gtctccaccg cctggtagtc ggcccgcagc
    36421 cccggcagga tcatccgtac gatctcctcg tcgtccagga gcgccgaagc ggtgccgctc
    36481 agggagcgga cctcggccag gaactccttg tcgccgagcc ggtgcgcgtc ctccacccgg
    36541 tgtaccgacg gggccctgcg gccggaggcg atgacgccga gcggcacacc gttcccctcg
    36601 cgttccccca gccgggccac ctcgtaggcg atgaccgcgc ccatgctgtg ccccatcagc
    36661 accagcggcc ggtccgtcca gccgcgcagc gcccggtgga cgccgtccgc cagttccgcc
    36721 agggaccgca acggcgcctc gtcacgccgg tcctggcgcc ccgggtactg cacgctgagc
    36781 gcctcgacgc gaccggtggc ggccagtgcc gccgagaagg ggaagaagaa cgacgccgaa
    36841 ccacccgcgt gcggcaggaa caccacccgc acccttgcgt ccgccaccgg atggaaccgc
    36901 cgcacccaca gggtgtcccc ggcgtcggca gcgccgcccg gcgcgcccgt tcccgtgctc
    36961 ctgtccgtgc tcatccacgt gactcctcac cgggcggccc cgcggggcgt gtccacatga
    37021 cggcgccagc ctaggtggcc ccgggcccca cccgaacccc taatcccacc ccgggccccg
    37081 acacggccac ccctgagaac tcgtgaaccg cccctgaagc caggcatgtt gagcatccgc
    37141 acgagcgcgt gtgagtacgc gtactcaggg ctcggcagcc ctccggcggc gagagtggtg
    37201 gcacaccgaa cgactggaga aagtcatgaa cacgtcccgc agagcgggct tcaccaccag
    37261 agtccgtcct ggacgcatgc gcatcgcggc cgccgctttc gcgagcgtgg ccgcggtggt
    37321 ggcgctcacc ggttgctccg gctgggagta ccgcgaagac gtctgcgcga gtggcgagta
    37381 ccccgtcctg tccgtgggcg gaaccggcag tgcctgcgtt tcggacggac aggaacctcc
    37441 gtcgggattc gcgcggtatc cgcagggcaa ggtgccgcag gaggtcggcg acaagtggga
    37501 cacgtactgg gacacccaca ccctggacaa ggagggcaac gtcatcgacg ccccggcgga
    37561 gggctgaccc cgacgcccgc atccggcggg catcccagtg catggcgccg cagggccgca
    37621 gccagtcgac ttgccggttc ctgcttaccg tgttcggtcg gcccgcgacg atccgacgtg
    37681 ccggttctgg agctgctgaa ggcccagcag gtcggcgaga caccggagtg gccgtcagcg
    37741 ataagggttc ccgacaacgg cgttggacgt gtcggtgggt gatcaggcag gtgtcgaggc
    37801 agaggaaggt ttcgtggatg tcgtcgcggc tctcccagcg gattcgcggc ggcggatgcc
    37861 gttcagccgt caggtcggcg tcgtggccga ccgaccgcgc cggccacggg tgggaccgtg
    37921 tccagcagcg gcagcaactg cgcgacgtcg ttgcggtttc cgccggtcag cgacaccgcg
    37981 agcgggatgc cctgtccgtc ggtgaggaca tggtgcttgc tgcccggccg tgcgcggtcg
    38041 accgggctgg gcccgcttgt cggccgcgca gggccgcccg cacgtgggag gagtcgatca
    38101 ccgcccgcga ccagtccagc ttcttcgccg ccgcagcttc ttcagcagca ccagatgcag
    38161 ctcgtcccac gcgccggccc gtttccacgc ggtcggcggt cgccaacagg catccccgag
    38221 ccgaagccca gttcctgtgg caggtgctcc cactggatgc cggtatgcag cacgcactgg
    38281 atcccgcaca acgcctgccg gtccggcagg cttgtgactg tggctcggcg gcctgtcggc
    38341 gacgcgacgc gcaacggcga tccgtggcgt acctggccta cttcgccgta acggtcgtga
    38401 tgtacgtgtc agtccacttc gagggcgtcc agggccagcg tgtgggcgat ggcgaggcgg
    38461 cggtcgatgt cgggcgcgag gatctcaagt acgtaccggg tgtgcagccc cagcttcttg
    38521 gtgacggtca tcagcggctt gccgctctcg gtgtactcga agcggtacgg ccagatgaac
    38581 ggcacgtatt cgagatacgg cacgaactcc cagacgaacc ggacgaaggc caccaccctg
    38641 ctgcgctcgc ggcaggtcag cttcgtcgtc cccggctgcc gcacctgcca tgtcctgcgg
    38701 aggaaagacg cgcccgcgtc ctcgtggaac gacccgaagg accggcccga agcgtcccgc
    38761 acgtcgtaca tgtagcccac ttcgtggtcg cggcccttga aagcggcgag aacggacttc
    38821 ctggacgcgt ccgtatagac ggtcacctgc cccctgagcg acagccgctt ctggcgtgcg
    38881 tatgcgacgg gctcgccctc ggagccgtcc ggccgtgcca cgctcaccac gtactcgccg
    38941 gtcgtgaggc tcagtgactt cttgatgacg aaggtgtcgt gggactggat gtccggtgct
    39001 tccgcggggg ttggggccgg ggctggggcg ggggcggcct tggtgagacc gacggcggcc
    39061 tcgtcctgct ccgcgcccgt tcctgtactc gactccgcgc cggtgctgtc catgtggatc
    39121 tcccgttgtc cccgtgtccc cgtttcggtc cgtccatcgt cggccgcacg accggcccgg
    39181 cgcagtctcc ggaagtcgtg atcccgtacg acgaaagatg tcaactttcg tcgtacggtg
    39241 gcacgacgct cggccgatgc aggcgctctt ccgggggcct accgtcggtc cggtgtatgc
    39301 ggacagggaa atggatgtgg atgtgcgggt gggtacggat gtgggagatc gacgggtacc
    39361 ttccgccggg ctcgccgttc ggggtctgcg gcggcggttg accggcggtg tgatctggag
    39421 ccccgcccgt atcgtcgggg aggcggtgct cgccgtcacc ctcgccgggc tcgccacggg
    39481 catcggcgcg tggatggaca ctatcggcgc gcagaccgtc ctcctcgccg gggcgatggc
    39541 cctgctggcg cccgcgcgcc acgcgctgcc cgcgaccgcc ctgatcctct ccgccccgct
    39601 ggccgggggg tggaatgtca tggcctccgt gctgctggtg tgcgccgcct ggtcggcggg
    39661 gcggcggatc acggaaccct ggcgggtggc cgccgcgttc ggggccgcgt gtgtgctcca
    39721 cactgtcccg gacctgtacc aggacatcgc ctcaggggtc gcgcctgtgc tgctcgtcac
    39781 cctcgggtgg aacgtcgcga cattcctcac ccttgccgtg gtgcctgccc tcgtcggccg
    39841 ctaccgggac caacggcggc ggctgctcga tgcgttgtgg ctgaacaacg agcaactcag
    39901 gcgcgagcag gcgatggtgg cccgcgaggc gcggctgctg gagcgcaacc gcatcgccca
    39961 tgacatgcac gacagcctcg gccaccagct cgccctgatc tccgtgcacg cgggcgccct
    40021 ccaggtcgac ccggagctga ccgcgaacca gcgggaggcc gtacggatcc tccggggtgc
    40081 ctccgtcacc gcgatggcgg agctgcgggc ggcggtgggg gtgctccacg acgaggcgga
    40141 gtacggggag taccgggaac accaggggca ccagccgcag tcggtgggcg acgccgcctc
    40201 ggtgtcgtac gcgccccgta ccatcgccgc catcgacggc ctggtcgagt cgtcccgggg
    40261 cgcgggcacg gccgtgtcgc tggaccgaag cggtgtccgg cggccgttgg cgcccgccgc
    40321 cgaccacgag gcgtaccgca tcgtccagga ggggctgacc aacgcccaca agcacgcgcc
    40381 gggcgccccg atacgccttg ccctgcggta cgaaccggac agcctggtcg tggaggtcac
    40441 caacgggccc gtgtcgggcg gagcgcccga ggtgccgccg gagatcagcg gcggccaggg
    40501 gctgaagggg ctgtgcgagc gggtcggccg ggtcggcggc atggtgcaca ccgggcccac
    40561 cgaggacggc ggcttccgga tcgcggggat gctgccgtac ggggaggaga gcaaggcggg
    40621 aagcggcgcg gagggccggg tggggaacct cgggggacac ggggcgggga gcggtgcgcg
    40681 gggcggcgcg ggaccgaatg gcgcgacctc ggtcgtatcg gctcgcgact ttcgggggca
    40741 gcggcgtccc ggggcggtgg gcgacggtgg aacggtcatc aacggggccg atccacaaag
    40801 ggagttcacc accactatga gtaccaggaa gaacgtcgcc atcggctgtg ccgtcaccgc
    40861 cgtcgtcctc gtcgcgggcg tcatcggcct gggcgtctgg gggatcggcg tcatgacgga
    40921 agaggtgaag aaggcggaca tctcgccgag cgtctacgag gaggcgaagg tcggggacgc
    40981 cgaggccgac atccaggcca ggctccccga agaggactcg tggctcacct cggacctggc
    41041 ggaccaaggg cccaagctgc ccgagggagc gacgtgccgg cacttcacct ccaaggacga
    41101 ccagggggcc gacgccctca ccgtcttccg gttctgcttc caggacggga agttggtctc
    41161 caaggagacg tacaaggcga agtgatgccg ggccccgtgc ggagggtcgg ccgctacagg
    41221 gcatgatggc ggggccactc catccgcttc tccatcacca cgtcatgatc gacaccgcgc
    41281 aggaggctgt gtgatccggg tcctcgtcgc cgacgacgag ccgctcatca gggccggcat
    41341 cagaatgatc ctcacctcgg ccgacgacat cgacgtgatc gccgaggccg gggacggccg
    41401 cgaggcggtg gagacggccc ggggcggcgg ggtcgacgtg gcgctgctgg acatccagat
    41461 gccggtgatg gacgggctga cggcgctggt cgaactcggc cgcgccgcgc cgaaggtacg
    41521 ggtcctgatc ctcaccacct tcggagagcg ggacaacgta ctgcgcacgc tcggccacgg
    41581 cggtgcgggg ttcctgctga aggactccgc gcccgacgag ctgatccagg cggtgcgggc
    41641 cgcggcggca ggtaacgcgt acctctcacc cgcagccacc cggcatgtgg cggacgcgct
    41701 ctccgccacc ggggccacca cgcgcgggga ggccgcgcgc cgccggctcg acgggctcac
    41761 cacccgggag cgcgaggtgc tggcgctgct cggggagggg ctctccaacg cggacgcggg
    41821 gcggcggctg catatgagcg aggccacggt gaagacgtac gtcagccgca tcctcaccaa
    41881 gctcgactgc gacaaccgag tccaggccgc cctcctcgct cgcgacgcag ggctccagcc
    41941 ggggggactt cagccgggca ggcactgacc ggacggagct acccagcctg ttgaccagca
    42001 gtgaacgccg tacggtggac acccggaagc agccacggac ccgtcaatga gcggtggccg
    42061 accctgcaga cctacaggtc gtcgtactca tcaggtgcct ccttcgggga agatcacatc
    42121 tgattcggct tgtgtggtga gggcatgctg agtaaccggt tggggatggg agcccaggct
    42181 ggctaggctc tcgtcatgag tggtccggtg ttggtgatcg agttggcgga gcccgtccca
    42241 ctcatatcca tccagcggct ccgggagctc cttgtccgtt cctcgtcgca ctttgaggag
    42301 aagcgggtcg gcgagtacga gctcaacatt cacgcggaga gcctcggcgt cgcctacacc
    42361 gggggcatcg acggaggccg gcctgtcatg gtctctctca tgggacccgg catcggcgac
    42421 gaggccgtct tcgaggccga gcacgccgac gaagtcgatc aggaacccct catcggcttt
    42481 accccgacac agccgtcgac gtcatagcgt tctgtaacag gccggtcgac cacgtcatca
    42541 cggccctgct gaccgctgct gtcatggacg tgatcggcgg cgtcgccaat gccgaacttc
    42601 ttgagggcca agtcccgatc gtgaccgacc ttcctggcat catcgcgacg atgacggatc
    42661 cgtggcctgc cgcctacggt tcggcggaat tcctcagagc gtgggctcgg cagcccggct
    42721 tccggctcct gaagtagccg cagaccagcc cgacaacctg ggaggttcgc gaccgagctt
    42781 ctccagcccg gactacagca gccccgactt tggcggcccg gaacaacaga gggaatgacc
    42841 gaccgcagcc ctctgccggc ccggactcgg acccgcagag tcgccgcaaa cggttccggc
    42901 accgcgaacg cgtgatggcg ctggccagcc ctgagctgtc ctggcttttc ggccaagacc
    42961 atatgatccg gccagacggt acctgccggg gcgtaagggg aagtcccgcc gccggccggc
    43021 ctcttgtccc tacccccttt gctacgtccg gtccaacgcc gcgaagacgg ccaggcacag
    43081 ggtgaggctc gcggcgaacg cgatgccgca gcgggacagg gccgccggca ccgcggcccc
    43141 ctcccagcgg gcgagggcga aggcgatcgc cgcggcgatg acggagaaga ggacggccac
    43201 cgccagcgca aggagcagca acgccgggaa ggtgtggttc atgagagcac cgcctggatc
    43261 gtgtggtgtc gatgacgaat tacgacgatc cccggacgga accgcaggtg gggcggttgg
    43321 atgtttctcc ggcgacaaca gggggttgtc cggcgaacaa accacggggg agacgagtgg
    43381 ccggcgagag gaagcgggcg ggacggccgt ggggaccggc ccagggctcg tgcgtcgaga
    43441 tcaaccagct ggtcgcggtg gtgcggacct ggctcgacga atcggagctg tccgtaaggg
    43501 agttgcacgc acggctcact cccgagcact tcgtggccgc agtcgtgcca gagttacgcc
    43561 agttacgtga ccggctgtcc ggcaagtcgc tggagtggga tctcgtcgag gccgtggccg
    43621 acgtgtgctt tccccacgag caggccgacc tctcccggca acgcctcggt caggcgaaga
    43681 cactgtggga ccgggcgggc gcgaacccca cgccgatcac ggagccacag gagctggtgc
    43741 ccgcccggga actgctggcc gccaaggacc gcaccatcga ggtccttcag gagatgcagc
    43801 gcgcccggca ggcctacgag gccggcgagc acgggcggca gcaggctctg tcgatcgcca
    43861 cattgctgtt cgtcatgctc ggacaggccc aggcgaaggt caccgaactg aggcgtcgcc
    43921 tcgacgcgct ggagtcggtg accgtagaac tccccgacgg ccaaggagta gtggagctcc
    43981 tctcccgggc gcaacggcag gagtcacaac tgtgtgaaca gctggtgcgc gcagagcggg
    44041 agcggggcat cgctcagcag gtcgccgacc acgccgcacg ccgcatccat gaactggagg
    44101 ccgaactcgc cgagctacgg ctccgcatgg gcgacgacga gacctcccga acgcaggagc
    44161 cggcaccgct gctgtcccag ctcgacatgc acgcgctcag ctccgacgat gccgcgctca
    44221 acgacgtgga ccgtgcactg gagaaggcgc gcgccgtcct cgacgaggaa cacgaagccg
    44281 ttcagcaagc cgccgacgag gtgggttact ggtcgccctc gattgcctcg ccttccccgg
    44341 cggaagccgg cgtctccgtg cccgaacagg ttcgccagca cctgggcgga caacccgccg
    44401 ggttgtccgg aacaacccag gacaacccgc cgaccagcca ggagacaacc ttccctgcac
    44461 tcgaatcccc gcagcctgcg gccgccgact ctcaggacga catcttcgag gcggctcgcc
    44521 ggatcacccg gggaagagac ccggaagaca tcgtgacgcg actgtgccgg gccgtcgtcc
    44581 ccaccgtcgc cgacgcggtc atggtctatc tgcgggaccc gatcccggtg ggcgatgaag
    44641 gacacgaggg cccgctggta ctgcggctgc aacaggtgca cccgccccac gccggcatgg
    44701 gttccgcacg gtgcgaggta cgccccggca gcgcgctctt cgaagtgctc aacggggcac
    44761 tgccggtcgc caccgactcg cccggcgctg gcgccgcgct gccggaactg atcggtatga
    44821 ggcatgaggt accacgcgga ggccacaccg tcctcgtgcc cctgcacggc cgcaggcgga
    44881 tcatcggcat agcggtcctc ctgcgccacc ccaaggggca cgccttccag gacgccgacc
    44941 tgtccgtcgc cgccgagttc gccaaccgca gcgccctcgc catcgacaag agccacagtc
    45001 ttcaggccgc ggtccagggt ctccatctcg cccgcagcct cgcggacacc ctgcagatcg
    45061 tcgccgacgg tctggtgact ggtctcggct acgaactggc gtgcgtcaac ctcgtccgca
    45121 cggacggcaa tctcgtcgtc gcctctttcg cgggcaatcc tgccgccgag gagctgatca
    45181 ccggccgcgt cggttcccgc gagtcctggg aacgtcggct gagcatgggc gaggcctggg
    45241 gcgacctgcg gttcataccg cacaccgaag gctgggtcct cgacgatgac gacgtaccgc
    45301 agtggtacac cgacggcccc gcccccagtt ccgaggacga gtggcacccc tccgaccgcc
    45361 tcttcgcgcc gctctacacc cgaagcgctt ccggtgcctc ccgcggtgag ctgctcggtg
    45421 tgatctccgt cgaccggccc ctcacacgcc ggcgtcccac gccggacgag cgccgggatc
    45481 tggaggagta cgccttccag gccgccatcg cgatcagcaa cgcgcggtta cgtgcgaaca
    45541 tgcaacgcgc actggtcaga caagaaagag agcagcaggc gctgcgggcc agcgaggaat
    45601 ccttccgcca agccttcgag tacgcaccca acggtatggc catcgccgag atgggcggcg
    45661 accaccacgg ccgcatcctc cagacgaacg acgcgctgtg ccgcatgctg ggccgcccgg
    45721 cctccgccat gcgccgttac tcgttctccg accttgtcca ccccgaagac ataggcactt
    45781 tgctccgcac cagctctgag ggcgggcacg cggaactgcg cctcgggcgc cgcgacggca
    45841 cgtacctgtg gacctcgctg cgcaacagcg tcgtcgcgga cgccgacgac ggcccccgct
    45901 tcctgctcac tcacgtcgag gacatcgagg agcgcaagca ccgcgagttc gaactcgccc
    45961 accgtgcctc gcatgacgac ctcacaggcc tgccgaactc cgccgagctg cacgcccgca
    46021 tcgacgcccg tctctgcgca ctcccggagc acggggccga cgccgccggg gagccacatg
    46081 acaactccta ccttggatac gacgaccagg ccgcgccccc tcacactcac gtatgggccc
    46141 ccgtacgcga ggacgacacc catggcctgg ccctgatttt cttcgccttg cgcgacttca
    46201 aggcgatcaa cacccagttc gggcacgacg cgggggacag cgtcctcgtc gaggtcgcac
    46261 ggcggctccg tcaagccata cgcgacaacg acacggtcgc ccggtacggc ggagacgagt
    46321 tcgtcgtcct cgccgacgac ttcggccccg ccgacgcaca caccgccgcg gtgtggatgc
    46381 agtcccagat ccacctgccg atctctctgg gcggccaggt ggtccgcatg cacgcgggtg
    46441 tcggtatcgc atgggcccag tgcgggacgt cccctagtga caccctgcgg gcggcccgcg
    46501 ggttcgcgtc gtgagcgaag gctttcaagg gccgatgcgc agaacggcgc cacctgcaag
    46561 gaattcaaac actactgaca agcgtgcgcg attggcgctg agattgatca tgaccctggg
    46621 ccgggcttct cggcgatcgt tcggcctcgg cacagcccgg ccggcggact tcctcggggc
    46681 ggcgatctcg ccgaggatcg ggtccggtgg cgggtgggca gttaccgggg gaccggttcg
    46741 acgggccggg gcgtgctgtc gaggatggcc agttcggtct cggtggcttg gcgtttccac
    46801 tcgggggcga cggtggcgta ggtggtgaca tcgtgccagc agccccgggt gcggaacagc
    46861 tggcgaagtg tggcctcggg gcgcaggccg gcggcgtgca tgatctgggc catgtggtgg
    46921 tggtcgctgc ggtggccggc ccagattcgg tgcaggccca ggtgcccgaa ggcgtaggcc
    46981 atcagcaggc gtccggcctc gtggccgtgg ccgcggaccg gggcgccggg cagcatgacc
    47041 agggcggtga gcatggcgtt gctgccgtag tcctcgacga gcagtcccat ggtgccgacc
    47101 atggtgtcgt cgtcgggggc gcagatggcg agggtgtact tgcgccgcgg gtgggtgtgg
    47161 ggctgggcga ggcattgggc gaaggcgtcg tgggcctggg cggcgtccat gcggtcgttg
    47221 cccaggtaac gggtgagggc gcggtgggtg aggatccgcg cgaaggtgtc gtggtcgccc
    47281 gcgtgcagtt cccgcaaccg cagatgctcg ccgcgcaggt cggggatgcg gttcacaagg
    47341 cggctccgtg cggcgtgggc agggtggaca cggtggggat gagggcctca aggtcggccc
    47401 agtggcggcc cgagggtacc ggctcgccga gcaggatgcg gcgggcagtg tcggtgatga
    47461 gagccgcgcc gagcatcacg ccactggcca gctgcggcca gctggacagg gtgcggccca
    47521 cccgggtgag ggcgtcgctc atggcggggc tcagccgctg cccgtcgacg attgtgagca
    47581 ggaagcggat ggtctcttcc cggctcaggc ccaccacgtc ggcggcggtc gtggtcccga
    47641 tgcggccgtg gaaaagcgga cggttcccgt cgaggtcgaa acgctcgatg tcgagcacgc
    47701 cccggtcgtt ggtgtccatc aggaccggga cccgccggcg gcgcgcgtgc tcacgggcgg
    47761 cgaccttcac ccacagggtg tcgcactcct caacgagcag gtccaggccg ttgtcctggt
    47821 caccgaagaa gtccccgacg ttctcctcgt tcaccccacc ccggtgaacc tcgatgtcca
    47881 ggtaggggtc gagctcatac attcgccggg cgcacagcac gctcttctcc aggcccagtt
    47941 cgtggacgcc tgcgcgcagc ctgttgaggt tcgacaggcc gaggtggtcg aagtcggcca
    48001 gccggaaggc accgccgacg ccttccatgg cgcaggtcag tgcggcgctg ctgcccaccg
    48061 acaggccgat gacgccgatg cggcgcagca gcaggcgctg ctgctgcccg cgggtgatct
    48121 tgttgcggtt gcggtcggtg cggaccaggc ggaactcggc ctcgggcagc acatggacca
    48181 ggcgccccga ccacgggtac caggcccacc tgccgtacct gtcgggccgg cccgacacga
    48241 ccttggcgac cgcccggtca agggcctgcg ggccgaagga ctcgccgggc gcctgacacc
    48301 ccacgagttc ggcgacctgg tcctcgatac ggtcgtggac ctcgcgtacc aggggcgagc
    48361 cacgcagcat ggacagggcc tgggcaccgg caggccggga ggggtccagc agcactggac
    48421 gaaacgattc actggcctgg cgaggcgaag gaaggacgaa ggaggccggc tccgggccgg
    48481 cggacagcga ctgagacaca acggcgacgc taacaatcca agatcaccga attcggggga
    48541 tcacccgccg gggcgcactc gaattgatct tctagctgaa tgcgcccccc tgaaagtaca
    48601 gggcctctgg cggggctgtg gcgcaccgcg cgatcagcgc gtaggccagg ggtagcggct
    48661 ggcgaggatc gtccactcct catccgcccg gccgggacag cccggccctc ggcctcccac
    48721 tgccgggcga gcccggtgaa ggtcagctcc agttcgcaac acgctttttc ccgcacacac
    48781 ggcgaggcac gagaataggc aaccgacggc tcagccggct gtcgaaagcg cggccccagc
    48841 gcggccagca caaccagcgc ctacaccgcg accgtcaccg tccgctagag ggtgttgcac
    48901 aggtctgtgt ttgggcaggt cagggcccgt ggtcatagtc ttctggtcat gatgtgagtg
    48961 ccagattgtg gatgtgggcg acggcttgga cggcggacgg cggagcggat gcggcgcgcg
    49021 ctatagcagg gagcctgctg gagaggatgg tgatgtgcgt cggtgacctg accgagcagg
    49081 acttgggcgg gtctgccgca caatcgggtg acatctcggg tgacatctga actggcttga
    49141 cgggtttccc cggggtggtc tgcgggtggt gtggtggggt cgggtggttg gggtgtgggg
    49201 gttggtgttg tggtgtgtgg gggtgtggtc aggctgggat gggtgcgtgt gcctgtgcct
    49261 gtgcctgtgc ctgtgccggg gcgggtgcct gtgcctgtgc tggggctggt gcgtgtgccg
    49321 gggcgggtgc tggggcgggt gctggtgtct gtgtgtgggt gggtgtgtgg gtgggggtgg
    49381 tgatg
//
