LOCUS       NZ_BMSI01000023        43729 bp    DNA     linear   CON 02-AUG-2024
DEFINITION  Streptomyces asoensis strain JCM 4185 sequence23, whole genome
            shotgun sequence.
ACCESSION   NZ_BMSI01000023
VERSION     NZ_BMSI01000023.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces asoensis
  ORGANISM  Streptomyces asoensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 94470)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014649075.1-RS_2024_08_02
            Annotation Date                   :: 08/02/2024 04:45:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,813
            CDSs (total)                      :: 7,736
            Genes (coding)                    :: 7,563
            CDSs (with protein)               :: 7,563
            Genes (RNA)                       :: 77
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 53 of 173
            Pseudo Genes (incomplete)         :: 140 of 173
            Pseudo Genes (internal stop)      :: 10 of 173
            Pseudo Genes (multiple problems)  :: 28 of 173
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:21:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 43729
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMSI01000023.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..43729
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="True"
                     /product="T1PKS"
                     /product="other"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /rules="(Neocarzinostat or bcpB or frbD or mitE or prnB or
                     CaiA or bacilysin or orf2_PTase)"
                     /tool="antismash"
     cand_cluster    1..43729
                     /SMILES="C(CC)=CC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /detection_rules="(Neocarzinostat or bcpB or frbD or mitE
                     or prnB or CaiA or bacilysin or orf2_PTase)"
                     /kind="neighbouring"
                     /product="T1PKS"
                     /product="other"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..27084
                     /SMILES="C(CC)=CC(=O)O"
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..27084
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[1780:7084](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1781..7084
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     gene            65..>238
                     /locus_tag="IE189_RS39875"
                     /pseudo=""
     CDS             65..>238
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012901.4"
                     /locus_tag="IE189_RS39875"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRSQVRFGPAIADLLGEGYSVFVESSAHPVLVHPVSEIVDEADDT
                     VRLRAVVAGSLRR"
     gene            347..1747
                     /locus_tag="IE189_RS36745"
     CDS             347..1747
                     /NRPS_PKS="Domain: PKS_DH (32-187). E-value: 1.5e-42.
                     Score: 137.7. Matches aSDomain:
                     nrpspksdomains_IE189_RS36745_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_PP (297-383). E-value: 9.3e-31.
                     Score: 98.0. Matches aSDomain:
                     nrpspksdomains_IE189_RS36745_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (391-459). E-value:
                     2.6e-08. Score: 26.6. Matches aSDomain:
                     nrpspksdomains_IE189_RS36745_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1047: phosphopantetheine-binding domain-containing
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF044701.1"
                     /locus_tag="IE189_RS36745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphopantetheine-binding protein"
                     /protein_id="WP_229901594.1"
                     /sec_met_domain="PP-binding (E-value: 5.4e-14, bitscore:
                     44.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELPTYAFDHERYWLRSAPAVDAVALGQVGGDHPLIGAVVGRPDS
                     GGFLTTSRWSVEAYPWLGDHVVGEVVVVPSAVLVELAIRLGDEVGCAVVEELSVDRPVL
                     LPLRGGRAVQMTVGEADGQGRRAVEVFSRADDAGLEGVWTRHAHGMLVPGPVTGSPSAS
                     GAVWPDGSPAAEVALDRAVSDADRYGLHPALLDAAVCTVLPPGMIVTRWSGVALLASGA
                     AAVRVRAARDAAGVSRLELVDATAAPVLTADAVVAEPFQPPSPEHAETTDTSVVRAGRR
                     TTRQVAASRLGGLAEQLAATPPVQREQLLLDLIRREVASVLGHSAPGKVDPDRAFQEVG
                     FDSVLAVELRNRLTGLVGIRLPATIIFDHPTPRGLMRRLLAELCPDAVGELAGREDEIR
                     RVLVSTPLSRFQELGLMEKLLHLVASPGGEGATAPDTAGPEQDARLLIEEMDADDLVER
                     AMRKAGKQ"
     aSDomain        443..907
                     /ASF="catalytic triad H,G,P inconclusive"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS36745_PKS_DH.1"
                     /evalue="1.50E-42"
                     /label="IE189_RS36745_PKS_DH.1"
                     /locus_tag="IE189_RS36745"
                     /protein_end="187"
                     /protein_start="32"
                     /score="137.7"
                     /tool="antismash"
                     /translation="HPLIGAVVGRPDSGGFLTTSRWSVEAYPWLGDHVVGEVVVVPSAV
                     LVELAIRLGDEVGCAVVEELSVDRPVLLPLRGGRAVQMTVGEADGQGRRAVEVFSRADD
                     AGLEGVWTRHAHGMLVPGPVTGSPSASGAVWPDGSPAAEVALDRAVSDADR"
     aSModule        443..1495
                     /domains="nrpspksdomains_IE189_RS36745_PKS_DH.1"
                     /domains="nrpspksdomains_IE189_RS36745_PKS_PP.1"
                     /incomplete
                     /locus_tags="IE189_RS36745"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       527..595
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS36745_0001"
                     /evalue="2.00E-08"
                     /label="PKSI-DH_m2"
                     /locus_tag="IE189_RS36745"
                     /protein_end="83"
                     /protein_start="60"
                     /score="26.7"
                     /tool="antismash"
                     /translation="WLGDHVVGEVVVVPSAVLVELAI"
     aSDomain        1238..1495
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS36745_PKS_PP.1"
                     /evalue="9.30E-31"
                     /label="IE189_RS36745_PKS_PP.1"
                     /locus_tag="IE189_RS36745"
                     /protein_end="383"
                     /protein_start="297"
                     /score="98.0"
                     /tool="antismash"
                     /translation="LAATPPVQREQLLLDLIRREVASVLGHSAPGKVDPDRAFQEVGFD
                     SVLAVELRNRLTGLVGIRLPATIIFDHPTPRGLMRRLLAEL"
     aSDomain        1520..1723
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS36745_PKS_Docking_Cterm.
                     1"
                     /evalue="2.60E-08"
                     /label="IE189_RS36745_PKS_Docking_Cterm.1"
                     /locus_tag="IE189_RS36745"
                     /protein_end="459"
                     /protein_start="391"
                     /score="26.6"
                     /tool="antismash"
                     /translation="AGREDEIRRVLVSTPLSRFQELGLMEKLLHLVASPGGEGATAPDT
                     AGPEQDARLLIEEMDADDLVERA"
     gene            1781..7084
                     /locus_tag="IE189_RS36750"
                     /old_locus_tag="GCM10010496_74730"
     CDS             1781..7084
                     /EC_number="2.3.1.-"
                     /EC_number="6.4.-.-"
                     /GO_component="GO:0034081 - polyketide synthase complex
                     [Evidence IEA]"
                     /GO_process="GO:0030639 - polyketide biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (36-462). E-value:
                     1.5e-179. Score: 589.3. Matches aSDomain:
                     nrpspksdomains_IE189_RS36750_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (571-869). E-value: 2e-99. Score:
                     324.6. Matches aSDomain:
                     nrpspksdomains_IE189_RS36750_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (936-1103). E-value: 3.9e-61.
                     Score: 198.2. Matches aSDomain:
                     nrpspksdomains_IE189_RS36750_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (1398-1577). E-value: 6.1e-60.
                     Score: 194.2. Matches aSDomain:
                     nrpspksdomains_IE189_RS36750_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1669-1755). E-value: 5.5e-26.
                     Score: 82.7. Matches aSDomain:
                     nrpspksdomains_IE189_RS36750_PKS_PP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009712605.1"
                     /locus_tag="IE189_RS36750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_74730"
                     /product="type I polyketide synthase"
                     /protein_id="WP_189928195.1"
                     /sec_met_domain="mod_KS (E-value: 1.1e-221, bitscore:
                     728.3, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 5.9e-92, bitscore:
                     300.1, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 2.7e-99, bitscore: 324.6,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 4.9e-62, bitscore:
                     201.3, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.4e-14, bitscore:
                     46.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSSEEKLVEALRASLIENERLESEIKKIRDSSDEPIAIVGMACR
                     FPGGVSSPEELWELIADGRSAVGPFPTDRGWDLENLYDPDLDRTGTTYVREGGFLHDVG
                     EFDAGFFGISQSETLVMDPQQRLMLETSWEAIERAGIDPAALRGRNVGVFAGVGGHDYA
                     TGFHSVPDELEGYLMTGGLASVLSGRVSYTLGFEGPAVTIDTACSSSLVALHMAVQSLR
                     SEESSLALAGGSSVMCTPAGLVLASRMRSLATDGQCKAFAASADGTNSAEGVGVLLLER
                     VSDAIRDGHEILGVVRATAVNQDGASNGLTAPNGPSQQRVIRQALASAGLSSADVDIVE
                     AHGTGTPLGDPIEAQALLATYGQGRDPGLPLWLGSVKSNLGHAGHAAGVAGVIKMVMAM
                     RHGVLPRTLNVDEPTPQVDWSTGAVELLAEAHEWPETGRPRRAGVSGFGVSGTNAHVIL
                     EQAPEQTSVTPPDGKARVLGDSVVPLVLSARGEAGLAGQAGRLASFLGQRQELDLLDVG
                     RSLVRSRGLLPDRAVVLAEDREEALAALDAVAAGESATGVVRGTAESVVGRTVFVFPGQ
                     GSHWAGMGRELLEASPVFATRMAACAEALDPLTGWSLLDVVRQAEGARSLDDLDVVLPV
                     SWALMLSLAALWEACGVVPDAVVGHSQGEIAAACFAGALSLPDAARLVVYRAEAIRAEL
                     SGRGGMASLVAGVKAVSVLVEEWPGLEIAAVNGPSTVVVSGELPALEELLARCRTEGIH
                     ARRILGANAAGHSSQMEVLRESFLEAIAAIPCGPSRVPLYSTVTGRLQDTTELDAEYWY
                     RNLRQTVQFDPAVRTLAGEGHGVFVEISSHPVLAQSVQDVLEELQAPAVVTGTLHRDEG
                     GPRRFLASLAHLHTHGVRITWETVLGSGTERPVDLPTYAFQRRRYWLDAADAGGDAPGL
                     GLDAADHPLLGAVTEIPGSDGVLFTSRLSLRTHPWLADHAAAGIVLVPGAAFVELAVRA
                     GDEIGCGLVGELVIERPLLLPGSGGVQVRVWVGEPDGSSHRTVQIHSRREEAGPRGSWT
                     RHACGRLVPEEGGADFDLTRWPPPGATAVDPDALADAYDGMAQAGYGYGPAFRGLRRAW
                     TRGEDVFAEVSLPEAAGKGDHYGLHPALLDSAMHACAFRTDMAGESPKLALPFVWRDVR
                     LHAAGTSALRVHLTPLALDTIRLRLADASGAPVAAVDSMVLRPVVPESLRVGSGASQEQ
                     MFRVAWEPVSVRSVRDEPDVARVTTAEDVRAVAATPPGMLLLDVSGNGRTDLAAVRDLT
                     GRVLKVVRAWLAEPAFQGVPLVALTRAGAVVRDGDPVPDPAVAAAAGLLRSAQSENPGR
                     IVLVDTDGTQASARRLPDVLASGQPQAALRGGAVAVPRLVKAAPADAPGRPLDPEGTVL
                     ITGGTGRLGRLAATHLVSKHKIRNLVLVSRRGPDAPGAAELEAEIEGLGAFVRIVACDV
                     SDRDSMVALLASVPEDAPLTGVIHTAGALDDGVVTSLTPERLDAVLRPKADAARILDEL
                     TRDLDLAAFVLYSSLSGIFGSAGQGNYAAANSYLDALAVRRRAAGLPATSLVWGWWGRG
                     SGMLDELDEANLKRFDRWNNAELTAQEGMELFDLALLHRDAVQVLAKMELHTPGDRTDS
                     ASVPPLLRGLVRVGRRPAREGATGADTLADRLAGAAPDQRGKILVDLVQREVVAILGYV
                     SADEVGPDTSFFDIGFDSLTAIELRNRLSALTGVRIPATFAFEYPTAELAAEELGERLE
                     LPMGSPDTSGT"
     misc_feature    complement(1822..1836)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.56"
                     /tool="antismash"
     aSDomain        1889..3166
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS36750_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="1.50E-179"
                     /label="IE189_RS36750_PKS_KS.1"
                     /locus_tag="IE189_RS36750"
                     /protein_end="462"
                     /protein_start="36"
                     /score="589.3"
                     /tool="antismash"
                     /translation="IAIVGMACRFPGGVSSPEELWELIADGRSAVGPFPTDRGWDLENL
                     YDPDLDRTGTTYVREGGFLHDVGEFDAGFFGISQSETLVMDPQQRLMLETSWEAIERAG
                     IDPAALRGRNVGVFAGVGGHDYATGFHSVPDELEGYLMTGGLASVLSGRVSYTLGFEGP
                     AVTIDTACSSSLVALHMAVQSLRSEESSLALAGGSSVMCTPAGLVLASRMRSLATDGQC
                     KAFAASADGTNSAEGVGVLLLERVSDAIRDGHEILGVVRATAVNQDGASNGLTAPNGPS
                     QQRVIRQALASAGLSSADVDIVEAHGTGTPLGDPIEAQALLATYGQGRDPGLPLWLGSV
                     KSNLGHAGHAAGVAGVIKMVMAMRHGVLPRTLNVDEPTPQVDWSTGAVELLAEAHEWPE
                     TGRPRRAGVSGFGVSGTNAHVILEQAP"
     aSModule        1889..7045
                     /complete
                     /domains="nrpspksdomains_IE189_RS36750_PKS_KS.1"
                     /domains="nrpspksdomains_IE189_RS36750_PKS_AT.1"
                     /domains="nrpspksdomains_IE189_RS36750_PKS_DH.1"
                     /domains="nrpspksdomains_IE189_RS36750_PKS_KR.1"
                     /domains="nrpspksdomains_IE189_RS36750_PKS_PP.1"
                     /locus_tags="IE189_RS36750"
                     /monomer_pairings="emal -> ccemal"
                     /tool="antismash"
                     /type="pks"
     cand_cluster    2356..43729
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(Neocarzinostat or bcpB or frbD or mitE
                     or prnB or CaiA or bacilysin or orf2_PTase)"
                     /kind="single"
                     /product="other"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    2356..43729
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[22355:23729](+)"
                     /cutoff="20000"
                     /detection_rule="(Neocarzinostat or bcpB or frbD or mitE or
                     prnB or CaiA or bacilysin or orf2_PTase)"
                     /neighbourhood="20000"
                     /product="other"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      22356..23729
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Neocarzinostat or bcpB or frbD or mitE or
                     prnB or CaiA or bacilysin or orf2_PTase)"
                     /neighbourhood="20000"
                     /product="other"
                     /protocluster_number="2"
     CDS_motif       2372..2419
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS36750_0001"
                     /evalue="9.50E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE189_RS36750"
                     /protein_end="213"
                     /protein_start="197"
                     /score="20.7"
                     /tool="antismash"
                     /translation="GPAVTIDTACSSSLVA"
     CDS_motif       2795..2839
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS36750_0002"
                     /evalue="4.20E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE189_RS36750"
                     /protein_end="353"
                     /protein_start="338"
                     /score="12.5"
                     /tool="antismash"
                     /translation="VEAHGTGTPLGDPIE"
     CDS_motif       3488..3544
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS36750_0003"
                     /evalue="3.90E-09"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="IE189_RS36750"
                     /protein_end="588"
                     /protein_start="569"
                     /score="28.2"
                     /tool="antismash"
                     /translation="VFVFPGQGSHWAGMGRELL"
     aSDomain        3494..4387
                     /ASF="Neither malonyl-CoA or methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS36750_PKS_AT.1"
                     /evalue="2.00E-99"
                     /label="IE189_RS36750_PKS_AT.1"
                     /locus_tag="IE189_RS36750"
                     /protein_end="869"
                     /protein_start="571"
                     /score="324.6"
                     /specificity="substrate consensus: emal"
                     /specificity="PKS signature: Ethylmalonyl-CoA"
                     /specificity="Minowa: emal"
                     /tool="antismash"
                     /translation="VFPGQGSHWAGMGRELLEASPVFATRMAACAEALDPLTGWSLLDV
                     VRQAEGARSLDDLDVVLPVSWALMLSLAALWEACGVVPDAVVGHSQGEIAAACFAGALS
                     LPDAARLVVYRAEAIRAELSGRGGMASLVAGVKAVSVLVEEWPGLEIAAVNGPSTVVVS
                     GELPALEELLARCRTEGIHARRILGANAAGHSSQMEVLRESFLEAIAAIPCGPSRVPLY
                     STVTGRLQDTTELDAEYWYRNLRQTVQFDPAVRTLAGEGHGVFVEISSHPVLAQSVQDV
                     LEELQAPAVVTGTLHRD"
     CDS_motif       3656..3724
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS36750_0004"
                     /evalue="9.70E-05"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="IE189_RS36750"
                     /protein_end="648"
                     /protein_start="625"
                     /score="15.5"
                     /tool="antismash"
                     /translation="LDDLDVVLPVSWALMLSLAALWE"
     CDS_motif       3731..3847
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS36750_0005"
                     /evalue="5.80E-18"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="IE189_RS36750"
                     /protein_end="689"
                     /protein_start="650"
                     /score="57.0"
                     /tool="antismash"
                     /translation="GVVPDAVVGHSQGEIAAACFAGALSLPDAARLVVYRAEA"
     CDS_motif       3947..3985
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS36750_0006"
                     /evalue="5.60E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="IE189_RS36750"
                     /protein_end="735"
                     /protein_start="722"
                     /score="13.2"
                     /tool="antismash"
                     /translation="AAVNGPSTVVVSG"
     CDS_motif       4196..4243
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS36750_0007"
                     /evalue="1.90E-05"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="IE189_RS36750"
                     /protein_end="821"
                     /protein_start="805"
                     /score="16.7"
                     /tool="antismash"
                     /translation="LDAEYWYRNLRQTVQF"
     aSDomain        4589..5089
                     /ASF="catalytic triad H,G,P found: False"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS36750_PKS_DH.1"
                     /evalue="3.90E-61"
                     /label="IE189_RS36750_PKS_DH.1"
                     /locus_tag="IE189_RS36750"
                     /protein_end="1103"
                     /protein_start="936"
                     /score="198.2"
                     /tool="antismash"
                     /translation="HPLLGAVTEIPGSDGVLFTSRLSLRTHPWLADHAAAGIVLVPGAA
                     FVELAVRAGDEIGCGLVGELVIERPLLLPGSGGVQVRVWVGEPDGSSHRTVQIHSRREE
                     AGPRGSWTRHACGRLVPEEGGADFDLTRWPPPGATAVDPDALADAYDGMAQAGYGYGPA
                     FRGL"
     CDS_motif       4673..4747
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS36750_0008"
                     /evalue="1.80E-07"
                     /label="PKSI-DH_m2"
                     /locus_tag="IE189_RS36750"
                     /protein_end="989"
                     /protein_start="964"
                     /score="23.7"
                     /tool="antismash"
                     /translation="WLADHAAAGIVLVPGAAFVELAVRA"
     aSDomain        5975..6511
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N found: True"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS36750_PKS_KR.1"
                     /evalue="6.10E-60"
                     /label="IE189_RS36750_PKS_KR.1"
                     /locus_tag="IE189_RS36750"
                     /protein_end="1577"
                     /protein_start="1398"
                     /score="194.2"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="GTVLITGGTGRLGRLAATHLVSKHKIRNLVLVSRRGPDAPGAAEL
                     EAEIEGLGAFVRIVACDVSDRDSMVALLASVPEDAPLTGVIHTAGALDDGVVTSLTPER
                     LDAVLRPKADAARILDELTRDLDLAAFVLYSSLSGIFGSAGQGNYAAANSYLDALAVRR
                     RAAGLPATSLVWGWWG"
     CDS_motif       5978..6079
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS36750_0009"
                     /evalue="1.50E-08"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE189_RS36750"
                     /protein_end="1433"
                     /protein_start="1399"
                     /score="27.2"
                     /tool="antismash"
                     /translation="TVLITGGTGRLGRLAATHLVSKHKIRNLVLVSRR"
     CDS_motif       6359..6466
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS36750_0010"
                     /evalue="3.70E-18"
                     /label="PKSI-KR_m4"
                     /locus_tag="IE189_RS36750"
                     /protein_end="1562"
                     /protein_start="1526"
                     /score="58.1"
                     /tool="antismash"
                     /translation="AAFVLYSSLSGIFGSAGQGNYAAANSYLDALAVRRR"
     aSDomain        6788..7045
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS36750_PKS_PP.1"
                     /evalue="5.50E-26"
                     /label="IE189_RS36750_PKS_PP.1"
                     /locus_tag="IE189_RS36750"
                     /protein_end="1755"
                     /protein_start="1669"
                     /score="82.7"
                     /tool="antismash"
                     /translation="LAGAAPDQRGKILVDLVQREVVAILGYVSADEVGPDTSFFDIGFD
                     SLTAIELRNRLSALTGVRIPATFAFEYPTAELAAEELGERL"
     gene            7165..7932
                     /locus_tag="IE189_RS36755"
                     /old_locus_tag="GCM10010496_74740"
     CDS             7165..7932
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006123013.1"
                     /locus_tag="IE189_RS36755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_74740"
                     /product="arylamine N-acetyltransferase"
                     /protein_id="WP_189928197.1"
                     /transl_table=11
                     /translation="MFDKDKYLEHLGFSGTPDASLETLRKIHREHQMRIPYDSGYALAL
                     DSSGDALGLAQAHFDLDAAFETIVLSGRGGICVELNFMFHRLLVELGFEVQVLAASTLL
                     PGGVWGPEVEHMVMRVTLDGEDWLADAGHAGISIVEPLPFSGETVVQDGIEFRLTRREE
                     YYFLEYKTRAKDWRDSYRFLPETRTTADWARWRDALPVEELVAHPRRRRRVIDNGQVTL
                     TANLFVSVEDGKERLRLIRDENELEKIVGTYWR"
     gene            8157..9536
                     /locus_tag="IE189_RS36760"
                     /old_locus_tag="GCM10010496_74750"
     CDS             8157..9536
                     /EC_number="2.5.1.54"
                     /GO_function="GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019984114.1"
                     /locus_tag="IE189_RS36760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_74750"
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="WP_189928199.1"
                     /transl_table=11
                     /translation="MTRSSEAAHGEVRGRNTRDARLADRLAAALDRPAAQQPEWPDPAR
                     ARTVVELLRTAPPIVAEPETAQLSERLAAVARGQAFLLQSGDCAETFAETTASHLRANL
                     GLLKRMSLLLARAAGLPVVPLARMAGQYAKPRSRSVDADGLPVYRGDMVNSAEPTLAAR
                     TCDPDRMLHAHEHAARAMTLARRAYAREQSNPRTGPSSYPHGTAGGRLVGTAEETGRDQ
                     GPRSEQIYVGHEMLLLDYECAPLRAAGLTTGPEPLLVSPLAHFLWIGERTRGLGDAHLA
                     VAELLANPIGVKIGPSTTPEEAVEYVRRLDPHATPGRLTLISRMGRSQVREVLPPIVEK
                     VTSTGHQVVWQCDAMHGNSRTTPDGRKTRHFDDIVAEIEGFFEVHRSLGTHPGGLHLEA
                     TGEDVTECLGGARGLGEADLPARYRTACDPRLNEEQSMELAFTVADLLAEAMRPAGTGS
                     P"
     misc_feature    9772..9783
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: strong, score: 21.4"
                     /tool="antismash"
     gene            9776..10936
                     /gene="rifK"
                     /locus_tag="IE189_RS36765"
                     /old_locus_tag="GCM10010496_74760"
     CDS             9776..10936
                     /EC_number="4.2.1.144"
                     /NRPS_PKS="Domain: Aminotran_1_2 (25-167). E-value:
                     1.3e-13. Score: 42.8. Matches aSDomain:
                     nrpspksdomains_IE189_RS36765_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="rifK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013222557.1"
                     /locus_tag="IE189_RS36765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_74760"
                     /product="3-amino-5-hydroxybenzoate synthase"
                     /protein_id="WP_189928201.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.1e-114,
                     bitscore: 375.8, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.6e-13, bitscore:
                     42.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNARPAPEFPSWPQYDDGERTGLIRALEQGQWWRVGGSEVDSFES
                     EFADFHGAPHALAVTNGTHALELALQCLGVGPGTEVIVPAFTFISSSQAAQRLGAVAVP
                     VDVDPDTYNIDVAAAASAITPRTRVIMPVHMAGLIADMDALDRLSADTGVTLLQDAAHA
                     HGARWQGKRVGELGTVAAFSFQNGKLMTAGEGGALLFPDEETYEAAFLRHSCGRPVTDR
                     RYLHRTAGTNMRLNEFSASVLRAQLSRLDAQLTLREQRWTLLSRLLGEIDGVVPQGGDA
                     RADRNSHYMAMFRIPGISEEGRNALVDTLVEAGLPAFAAFRAIYRTDAFWETAAPDTTV
                     DKLAGSCPHTEAISTDCVWLHHRVLLASEEALHITAEIVADAVAAR"
     aSDomain        9851..10276
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS36765_Aminotran_1_2.1"
                     /evalue="1.30E-13"
                     /label="IE189_RS36765_Aminotran_1_2.1"
                     /locus_tag="IE189_RS36765"
                     /protein_end="167"
                     /protein_start="25"
                     /score="42.8"
                     /tool="antismash"
                     /translation="ALEQGQWWRVGGSEVDSFESEFADFHGAPHALAVTNGTHALELAL
                     QCLGVGPGTEVIVPAFTFISSSQAAQRLGAVAVPVDVDPDTYNIDVAAAASAITPRTRV
                     IMPVHMAGLIADMDALDRLSADTGVTLLQDAAHAHGAR"
     gene            10933..12033
                     /locus_tag="IE189_RS36770"
                     /old_locus_tag="GCM10010496_74770"
     CDS             10933..12033
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019984884.1"
                     /locus_tag="IE189_RS36770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_74770"
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="WP_189928204.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 8.4e-25, bitscore:
                     80.2, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 5.5e-18,
                     bitscore: 57.5, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLRAAVVGLGWAGRELWLRLLSEHEDFEVVAAVDPDPASRAAAV
                     AMGLPAHTTMDALDSRTVDLAVVAVPNHLHAEVAAALLRRGISVFLEKPVCLTTAEADA
                     LAAAEHSGGMLLAGSAAAHRGDVQRLAGLLPQVGRIRHVTLAWVRARGVPQPGGWFTQR
                     SKSGGGVLVDLGWHLLDVLTHLLGPAPVTQVIGSVSDDFVSSGAWSAAWREDRSTDVPA
                     GNVEDTARGFLLREDGISVALQASWASHEALDASVVTVEGSRGTARLHCTFGFSPNRAP
                     ERVLTLTREGTTERIPLPAEPIGAEYGRQLDGLAGLLADPGRRGVAVAQARDTVQLVES
                     FYASARGARPTDHAPRCTSHQEVSTA"
     gene            12030..12728
                     /locus_tag="IE189_RS36775"
                     /old_locus_tag="GCM10010496_74780"
     CDS             12030..12728
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019886424.1"
                     /locus_tag="IE189_RS36775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_74780"
                     /product="HAD-IA family hydrolase"
                     /protein_id="WP_189928206.1"
                     /sec_met_domain="HAD_2 (E-value: 2.5e-33, bitscore: 108.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTGSHHHAGTTSEQRSPVSRHAVVFDLDGVVVDSFAVMGEAFSL
                     AYAEVVGPGEAPFEEYRRHQGRYFPDIMRIMGLPPEMEEPFVRESYRLARHVQVYDGVA
                     DVLRTLNERGLRLAVATGKAGERARSLLDVLGLLPYFAHVIGSDEVPRPKPAPDIVHRA
                     LELLGVPAERAVMIGDAPTDLASAQGADVTAAAALWGCHDVTGLLAAGPDIVLRRPADL
                     LVLCPAVPGR"
     misc_feature    complement(12818..12836)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.02"
                     /tool="antismash"
     misc_feature    12857..12877
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.19"
                     /tool="antismash"
     gene            12862..13380
                     /locus_tag="IE189_RS36780"
                     /old_locus_tag="GCM10010496_74790"
     CDS             12862..13380
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020131923.1"
                     /locus_tag="IE189_RS36780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_74790"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_229901595.1"
                     /transl_table=11
                     /translation="MEETTKAHSSPARIRWLTDEQQRVWRSFVHATTLLEDHMCRQLQR
                     TVNMPHSYYLLLVNLAESPHQRLQMSELAMHAKITRPRLSHAVARLEKDGLVRREEAPS
                     GKRGTFTVLTEEGLEALGRAAAGYATVVQHALFDRLTPQQQESLGAIMQIVTEGLQTDR
                     AGADLPWLR"
     gene            complement(13454..14320)
                     /locus_tag="IE189_RS36785"
                     /old_locus_tag="GCM10010496_74800"
     CDS             complement(13454..14320)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /GO_process="GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1095: 3-hydroxybutyryl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020139665.1"
                     /locus_tag="IE189_RS36785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_74800"
                     /product="3-hydroxybutyryl-CoA dehydrogenase"
                     /protein_id="WP_307822248.1"
                     /transl_table=11
                     /translation="MERLGVVGGGTMGAGLAEVSLRAGVEVTVLVSAPHRIEDAVGRLT
                     AAFARAVAKGRMTEPEQAAAMGRLRVTADVGGLADRQFVVEAVTERLDVKQRVLKAVDE
                     VLTDPAAVLASTTSSLLVGDLAEATGRAGSVVGMHFFNPVPLMPLVEVVVTDRTSQQCA
                     ASAESFARDTLGKEVIRTADRSGFVVNALLVPYLMAAVRMYEQGIADADDIDRGMVLGC
                     GHPMGPLALLDLIGIDTITDVARSMAENSDGLVLDLPPLLTRMVQEGRLGRKTGHGFHR
                     YDEPSRS"
     gene            complement(14329..15372)
                     /locus_tag="IE189_RS36790"
                     /old_locus_tag="GCM10010496_74810"
     CDS             complement(14329..15372)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019070821.1"
                     /locus_tag="IE189_RS36790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_74810"
                     /product="3-oxoacyl-ACP synthase III family protein"
                     /protein_id="WP_229901596.1"
                     /sec_met_domain="fabH (E-value: 2e-90, bitscore: 295.4,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVQRDQGYVTSVLGTGSYLPERVVTNEEIEARVPGASAGWIADR
                     TAILERRYAAPDEAASDLAVHAARAALDQAGVDADGIDFIIVATTTGDAPIPSTASLVQ
                     LALGARRAACFDVNIACTGFVTALSIARAYVALDPATKVLVIGSDVWTRFIDFGDRATS
                     VLFGDGAGAAVVGSVPHAPGDPERGLLKVELVSRADAHELISMPAGGSRRPASVETVAD
                     GGHLLSMRGRGVRDFVLDNVPGLIAGLLKRSGCQPADVRHFVPHQANGRLVAELAEASG
                     LERARTHLPLCHSGNIGSASVPVALDAANRSGVLRDGDLVLLAGFGAGMAAGAALLRWT
                     GTEGGAR"
     gene            complement(15369..16727)
                     /gene="ccrA"
                     /locus_tag="IE189_RS36795"
                     /old_locus_tag="GCM10010496_74820"
     CDS             complement(15369..16727)
                     /EC_number="1.3.1.85"
                     /GO_function="GO:0043880 - crotonyl-CoA reductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (50-411). E-value: 1.5e-23.
                     Score: 75.4. Matches aSDomain:
                     nrpspksdomains_IE189_RS36795_PKS_ER.1"
                     /codon_start=1
                     /gene="ccrA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020139663.1"
                     /locus_tag="IE189_RS36795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_74820"
                     /product="crotonyl-CoA carboxylase/reductase"
                     /protein_id="WP_189928210.1"
                     /sec_met_domain="ADH_N (E-value: 3.9e-10, bitscore: 32.0,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.2e-24, bitscore:
                     79.2, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMSLSDAVRAGAGPRELAAAEVPAEFLAAHLRIEDEKTFEGIEGD
                     RDVRNTLHVGAVPMPELAPDEVLIAVMASSINYNTVWSATFEPLSTFGFLQAYGRQGGW
                     AKRHDRPFHVLGSDAAGVIVRAGSGVRRWRVGDHVLVNAACVEDQEASVQADGMLSENQ
                     LAWGFETNYGGLAHYTIARASQLIPKPAHLAWEEAASIPACGGTAYRMLVSDRGARMKQ
                     GDVVLIWGASGGLGSYAVQLVKNGGGIAVGVVGSEEKARAARALGCDLVINRQEHDFGG
                     DTDDEPEVAVAQGKRLGRLIRDGVGEDPHIVFDNVGRSTFGISVFLARRGGTVVTCGSS
                     TGYQHRFDNRYLWMRLKRIVGSHVANLQEQVDTARLFDQGSLVPALTSLFPLEETGEAT
                     RLVQLNQHIGKVGVLCLADRPGLGVTDPERRARIGEDRLTLMRAYAHDGVRAA"
     aSDomain        complement(15495..16577)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS36795_PKS_ER.1"
                     /evalue="1.50E-23"
                     /label="IE189_RS36795_PKS_ER.1"
                     /locus_tag="IE189_RS36795"
                     /protein_end="411"
                     /protein_start="50"
                     /score="75.4"
                     /tool="antismash"
                     /translation="TLHVGAVPMPELAPDEVLIAVMASSINYNTVWSATFEPLSTFGFL
                     QAYGRQGGWAKRHDRPFHVLGSDAAGVIVRAGSGVRRWRVGDHVLVNAACVEDQEASVQ
                     ADGMLSENQLAWGFETNYGGLAHYTIARASQLIPKPAHLAWEEAASIPACGGTAYRMLV
                     SDRGARMKQGDVVLIWGASGGLGSYAVQLVKNGGGIAVGVVGSEEKARAARALGCDLVI
                     NRQEHDFGGDTDDEPEVAVAQGKRLGRLIRDGVGEDPHIVFDNVGRSTFGISVFLARRG
                     GTVVTCGSSTGYQHRFDNRYLWMRLKRIVGSHVANLQEQVDTARLFDQGSLVPALTSLF
                     PLEETGEATRLVQLNQHIGKV"
     CDS_motif       complement(16002..16061)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS36795_0001"
                     /evalue="5.60E-04"
                     /label="PKSI-ER_m5"
                     /locus_tag="IE189_RS36795"
                     /protein_end="242"
                     /protein_start="222"
                     /score="12.6"
                     /tool="antismash"
                     /translation="GDVVLIWGASGGLGSYAVQL"
     gene            complement(16921..17676)
                     /locus_tag="IE189_RS36800"
                     /old_locus_tag="GCM10010496_74830"
     CDS             complement(16921..17676)
                     /NRPS_PKS="Domain: Thioesterase (23-245). E-value: 3.1e-56.
                     Score: 183.3. Matches aSDomain:
                     nrpspksdomains_IE189_RS36800_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018538269.1"
                     /locus_tag="IE189_RS36800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_74830"
                     /product="thioesterase II family protein"
                     /protein_id="WP_189928212.1"
                     /sec_met_domain="Thioesterase (E-value: 2.5e-55, bitscore:
                     180.4, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.6e-15, bitscore:
                     49.5, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 9.4e-07, bitscore: 21.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHRATAQFEKWVSVSHPAPLSSVRLACLPYAGGSASFFFPVSRAL
                     HPSVEVLALQYPGRQTRLHEPRIDNVPEFADQIFAALRHLDDKPLALFGHSMGAVLAYE
                     VALRMQDAGLPAPVRLFASGRRAPSRGAGGRVHTGSDAELVSELRELSGTNEMLLGDPE
                     VLAMILPAIRSDYTAIERYRHEPGRRLDCPVTVLTGDRDPRVSLDEAEAWAEHTTGTSE
                     TKVFRGGHFFLVDHMAEVVGLVARRLGPF"
     aSDomain        complement(16942..17607)
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS36800_Thioesterase.1"
                     /evalue="3.10E-56"
                     /label="IE189_RS36800_Thioesterase.1"
                     /locus_tag="IE189_RS36800"
                     /protein_end="245"
                     /protein_start="23"
                     /score="183.3"
                     /tool="antismash"
                     /translation="RLACLPYAGGSASFFFPVSRALHPSVEVLALQYPGRQTRLHEPRI
                     DNVPEFADQIFAALRHLDDKPLALFGHSMGAVLAYEVALRMQDAGLPAPVRLFASGRRA
                     PSRGAGGRVHTGSDAELVSELRELSGTNEMLLGDPEVLAMILPAIRSDYTAIERYRHEP
                     GRRLDCPVTVLTGDRDPRVSLDEAEAWAEHTTGTSETKVFRGGHFFLVDHMAEVVGLVA
                     "
     CDS_motif       complement(17353..17415)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS36800_0001"
                     /evalue="2.80E-08"
                     /label="NRPS-te1"
                     /locus_tag="IE189_RS36800"
                     /protein_end="108"
                     /protein_start="87"
                     /score="26.2"
                     /tool="antismash"
                     /translation="KPLALFGHSMGAVLAYEVALR"
     misc_feature    complement(17745..17759)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.6"
                     /tool="antismash"
     gene            17869..19503
                     /locus_tag="IE189_RS36805"
                     /old_locus_tag="GCM10010496_74840"
     CDS             17869..19503
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010070089.1"
                     /locus_tag="IE189_RS36805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_74840"
                     /product="bifunctional
                     3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid
                     hydroxylase"
                     /protein_id="WP_229901597.1"
                     /transl_table=11
                     /translation="MPETSPHKQPAGAGPETDADVIVVGNGPVGATLGILLAQRGRRTV
                     VLERRGRPYTLPRATSFDGETARLLAGCGTGPGLGRITEPATGYQWHSADGEVLLDIAF
                     RAEGPYGWPDASTVHQPALEELLASRAAALPGSTVVRGRRVVGIEEQDDRVVVTAEDED
                     GAARTYTARWVVGCDGANSFVRDHLEVPVTDLGFSYEWLLCDVRLHEPGEFVPTNVQIC
                     DPARPTTLVGSGPGHRRWEFMRLPGERAADLNREETAWRLLAPYGVTPDTATLLRSTTY
                     IFQSRWAERWRAGRVLLAGDAAHLMPPFAGQGMCSGIRDVVNLVWKLDLVAGGLAPESL
                     LDTYTEERRAQVHRSILSSVQLGRVICVTDPSAAAERDSTILAGRRGRGPALPDLASPL
                     TEGLLHRRADGSPLSPAGEVVPQGRVRGLSGTGLFDDVVGRGFVLMLAEGADAGLDAER
                     SAFLADLGTHVVTLLPEDGTPQSMSVADVGGVYRAFLARHGADAVLIRPDYHVYGAASG
                     LGAAAALVDDLRARLSSSSKEPTNCPT"
     gene            19703..20107
                     /locus_tag="IE189_RS36810"
                     /old_locus_tag="GCM10010496_74850"
     CDS             19703..20107
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009719519.1"
                     /locus_tag="IE189_RS36810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_74850"
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="WP_189928214.1"
                     /transl_table=11
                     /translation="MQRGEVWWVGFDERRLFVLLSAEDASGIQAMQVVEPAGVDISGLA
                     VEVPVGATEGLPFEGVLRFAFTRPGFIPCTWLTTVARDDLVERAGVLSSEKLGEIEDAL
                     RIAGQPQEWTATAAAKLSDMKDALRLGRPE"
     gene            complement(20220..20705)
                     /locus_tag="IE189_RS36815"
                     /old_locus_tag="GCM10010496_74860"
     CDS             complement(20220..20705)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971393.1"
                     /locus_tag="IE189_RS36815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_74860"
                     /product="hypothetical protein"
                     /protein_id="WP_189928215.1"
                     /transl_table=11
                     /translation="MAFRHPDGDFAITAMYSVPDDAWYLELDLVAGQRALVTAIVPDED
                     PAREPTVCFDPRAEHVDVPYEVMRWFMQQVDEEIRTSRAWMRLRPELVEIIHRLRQEHM
                     GVIDDDAFPQVLADVRAMVPEEDLPDVLEAAFGRQPDGTTMDHPQTPRPVGDQGDRV"
     gene            complement(20805..22004)
                     /locus_tag="IE189_RS36820"
                     /old_locus_tag="GCM10010496_74870"
     CDS             complement(20805..22004)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607916.1"
                     /locus_tag="IE189_RS36820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_74870"
                     /product="PAS domain-containing protein"
                     /protein_id="WP_189928216.1"
                     /transl_table=11
                     /translation="MGDPSLKTPLKNLPVFWTEVDEPWQTEDANPGGPRRAGEQCTGGP
                     AAPDGSQHAPDHGPVEGGPAVSRGYAAFADLVCLAPAAAFIRDRDGRYLWANHAYAHLY
                     GTVPEQLVGRYIEDFDAPAEADRFRALDQQILTRGTPVRHTLRYLRQDGTTGRAVGHRF
                     PVREESRTCVAGIYVDITDHLRATEQRQEAEENLSALRDHSGLPCALLSANGRVIEASV
                     AAAELFHLGLTDLVGRRAHTLLAPQPVPDLERLHRRWNSLIARRTRRVETTAVLVDTHG
                     LQRRAELHLTTIGHSAGRARHVWAVITHQSLAHEAHPPLTAAQIRILSLLAQGSSNGDI
                     AASLHLSRQTLDYHLSRLRHLLGAATRPALVARAYVLGILAPHVWPPRSATAAHPLSTA
                     "
     misc_feature    22063..22083
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.06"
                     /tool="antismash"
     gene            22356..23729
                     /locus_tag="IE189_RS36825"
                     /old_locus_tag="GCM10010496_74880"
     CDS             22356..23729
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) other:
                     bacilysin"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004949665.1"
                     /locus_tag="IE189_RS36825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_74880"
                     /product="acetyl-CoA carboxylase biotin carboxylase subunit
                     family protein"
                     /protein_id="WP_189928217.1"
                     /sec_met_domain="bacilysin (E-value: 3.6e-59, bitscore:
                     192.8, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTVLLVHAKGGPPLGHVLSRTAARADVHLLALSALPPAVAGSAG
                     RLCASVTTPDDRGRRDLVSLIVSHAREVGADAVTTFSEYAVVAVAEACETLGLPGAGPA
                     AALARDKRLMRGTWQRSGLPQPAFRPVATEADLQDAVDSLSCPLLLKAAWSAGSTAHQI
                     IGSAAEASAAWARSRQVMEDSARLGYAELHVAEADADFVVEEIVSGTAADWFDEPGWGD
                     YLSVEGVVADGVFHPVCLSGRMPTVEPFTERAGITPALLSPEAQDRVVDLARRAVDALG
                     LRDCGTHTEIKLGSDGSMWLIETAARFGGAMTVPQIEEVFGLDLVGMLVDQLLGRPVAW
                     PAQALTPAQARGAAGSLVVLAVDGRGEAWQDRRIWDFPVVASHVPLSPDSELSVVAESS
                     LPDGGVVPVYDPAAGANTMAALCLLSAADPRTVLKDFETLVDALPRVLPAAQGEEVPA"
     gene            23726..25732
                     /locus_tag="IE189_RS36830"
                     /old_locus_tag="GCM10010496_74890"
     CDS             23726..25732
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PPDK_N"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091958.1"
                     /locus_tag="IE189_RS36830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_74890"
                     /product="PEP/pyruvate-binding domain-containing protein"
                     /protein_id="WP_189928218.1"
                     /sec_met_domain="PPDK_N (E-value: 5.5e-35, bitscore: 113.5,
                     seeds: 105, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTHLATGTAEPATDRTVVGENLSLPLFRTLSGVLAGHPYLKVVV
                     DREENVWHLLDTAAHPFHVDYVATRVLGMDLAALDARLDAFNASVYTDPERRFLLGVLS
                     LHTEQEDGRERPFLVLETTEADTMNGDMLTYFYEFVRARLDSGLPLLLKPANHGQEEQL
                     SAIGEQRVPRVLGHELFGSRERTPLNPGDATGRLRFFRTAEEYRAAEFGLGWADIVAMP
                     CLPDDVPRVAGFVNTAPITPLSHTNVLASGWGIPNAIVRDLEQLVDQEGLDGAWVRYRV
                     DEDDISLQRLDHEPDLRAPAWHQQRIRLEPPLLEDAPVLSLHRLRGSDRDRYGTKAANL
                     GELHHVLDSRTVDLTAYYGRPRPPREDLYGHLAARLGLTDFTAEQLRFRAAEFVAEAVG
                     APDGVALPFALQQRFLASSPALQQGIGKLKMALELDAVDVLDSLCLHLQHLIRHTPVPE
                     AVTRQIEHAFPASAASRGRLVVRSSSNAEDLPGFSAAGVYDSVTTVHGTGELLDAVRQV
                     WASLVSPRSVRLRHQVGISLDETYMGVIIQEYVPASLGGVLVTCNPTRREDFRNVYLNC
                     SPGSPEQVVDGTVLPQQYLYNTVEGGGRTVALGSWGEGLSAAVRARLGDLSLTGRLLQS
                     HFSGTDVDKPLDIEWLMTEQGDFRLVQIRPYAL"
     gene            25729..27171
                     /locus_tag="IE189_RS36835"
                     /old_locus_tag="GCM10010496_74900"
     CDS             25729..27171
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019359352.1"
                     /locus_tag="IE189_RS36835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_74900"
                     /product="MFS transporter"
                     /protein_id="WP_189928220.1"
                     /transl_table=11
                     /translation="MRARLGRSRPGSEAATGLTDTARRIIRLNYGFQLLFNLLWWMPVF
                     YAYQKAAGLSDAQIFGIQSIYYVAFCLLEIPTGLIADRIGTRNCLRAGAVVMTAANLAP
                     VVSASYTGFLLHFLAIAAGRSLTSGAASAYLYDGLRAQRCDEHYLRAEGTARALGLAAK
                     VVCWPLVGPLMTLAHPAPYVLSAASAAGSLVCAVLLPRLAGTEAAADPGRSSGGRRGSA
                     FLRDAGTALRCVASSPWLALVMVQGVAVFTLSRICQVNLFQPILLDHGIGESSHGGVLA
                     AMTVAEAVASARPQWLSRRLPPVAWVSVLSLALAGTLAAMTLGGPWVVVVLLCLFAAAT
                     GFAFPVQRKLVNDAVPAHAPRATLLSVESIVDRAVCALAAIAAGAYLSAGHLDALLWHS
                     ALATALLLGVFQLLLRSGAVARDGWDGEAAPPRPRPDAGAEADDTSPAAAGEGAPDRAE
                     AADAGFTEVLEPDRARRAPRTP"
     gene            complement(27209..27904)
                     /locus_tag="IE189_RS36840"
                     /old_locus_tag="GCM10010496_74910"
     CDS             complement(27209..27904)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004949654.1"
                     /locus_tag="IE189_RS36840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_74910"
                     /product="hypothetical protein"
                     /protein_id="WP_229901598.1"
                     /transl_table=11
                     /translation="MAMTGGDGTVHVNGFASNASARAGLALGAALASTLLCAPATTAAP
                     EEGGTVRGAAALAPAPAPAPAPAPGERSCPVVYFDLGETLVHTADDGSTAYLPGAASYL
                     RTLRERHIRVGLITNVPPSWGTTDAERAARLRTEVDATWRGPTAFAWADFGDRIRTPRT
                     EAERKPSPVLWQRAKEGSGGCRVVYEAETAQEVSVASSVGFVSYQVGLPHRPAFLPAGL
                     VELLGRRPG"
     gene            complement(27947..28969)
                     /locus_tag="IE189_RS36845"
                     /old_locus_tag="GCM10010496_74920"
     CDS             complement(27947..28969)
                     /EC_number="3.1.2.-"
                     /NRPS_PKS="Domain: ECH (11-201). E-value: 3.2e-35. Score:
                     113.5. Matches aSDomain:
                     nrpspksdomains_IE189_RS36845_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019432503.1"
                     /locus_tag="IE189_RS36845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_74920"
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="WP_189928222.1"
                     /transl_table=11
                     /translation="MTDNAAGEILADVHRGVGRILLNRPEALNALTTDMVLAIDRVLAE
                     WEHARLSRVVLASTGPKAFCAGGDIRTIREHSLAGDAGASERFFASEYRLNARIAEYGV
                     PVVSLIDGLCMGGGLGLSVHGGFRVVTERAVLAMPETAIGFFPDVGASYFLPRLPGAIG
                     MYLGLTGHRLDAADALYTGLGTHFVPSHELEAVGDALADHPDEPVDVVLSRLAGRSPVA
                     RSRLAAVRGDVDRAFGAPTLGEIEDRLGHLGTAWASSALAALESASPHSLDVTHDLLAR
                     GRQRTLRECLDAELALTRTLIRTPDFLEGVRAALVDKDRTPVWRPARQGRPRRGAESSQ
                     "
     aSDomain        complement(28367..28936)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS36845_ECH.1"
                     /evalue="3.20E-35"
                     /label="IE189_RS36845_ECH.1"
                     /locus_tag="IE189_RS36845"
                     /protein_end="201"
                     /protein_start="11"
                     /score="113.5"
                     /tool="antismash"
                     /translation="DVHRGVGRILLNRPEALNALTTDMVLAIDRVLAEWEHARLSRVVL
                     ASTGPKAFCAGGDIRTIREHSLAGDAGASERFFASEYRLNARIAEYGVPVVSLIDGLCM
                     GGGLGLSVHGGFRVVTERAVLAMPETAIGFFPDVGASYFLPRLPGAIGMYLGLTGHRLD
                     AADALYTGLGTHFVPSHELEAVGDALA"
     gene            29117..29542
                     /locus_tag="IE189_RS36850"
                     /old_locus_tag="GCM10010496_74930"
     CDS             29117..29542
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE189_RS36850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010496_74930"
                     /product="hypothetical protein"
                     /protein_id="WP_189928224.1"
                     /transl_table=11
                     /translation="MRTRMLGRLLGGLLAAGLVMGTAGAGHAAPTASGTTAAAPARTSA
                     TAAKAAAYPKVYLNTVVNQWTHWTPDYYDSTHAGWLYAGSNYFYCLKEGVYYTDNGRRS
                     RYWLLTDDDSGNRNVYVSEVYLDQWGWDNVYSLLDYC"
     misc_feature    complement(29135..29144)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            complement(29566..30363)
                     /locus_tag="IE189_RS36855"
                     /old_locus_tag="GCM10010496_74940"
     CDS             complement(29566..30363)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012382345.1"
                     /locus_tag="IE189_RS36855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_74940"
                     /product="phosphotransferase enzyme family protein"
                     /protein_id="WP_229901599.1"
                     /sec_met_domain="APH (E-value: 1.8e-10, bitscore: 33.4,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQRDEERRDEEQPLPGGNVSAGVVRVGDTVRRPSGPWTPAVHALL
                     THLYEVGYRAAPRPLGIDDQGREVLTFMPGHVVWPDRFSLLDAEGHLADVARLIRDFHE
                     AVRGFTPPPDAHWQVLIPAEGSDIIAHQDLAPWNLVAGDEGRWAFIDWDTAGPGSRLWD
                     VAYAMHGFIPLSAHPDWQRPDAAARLRVFADAYGLDEAERRHTVPLLGRRTRSMHDFLR
                     DRAARGVQPWATLWAEGHGTAWRNDAEYIEEREEQWLRALLAG"
     gene            complement(30413..31645)
                     /locus_tag="IE189_RS36860"
                     /old_locus_tag="GCM10010496_74950"
     CDS             complement(30413..31645)
                     /EC_number="6.3.2.2"
                     /GO_function="GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0042398 - cellular modified amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1165: carboxylate-amine ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007262230.1"
                     /locus_tag="IE189_RS36860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_74950"
                     /product="glutamate--cysteine ligase"
                     /protein_id="WP_229901600.1"
                     /transl_table=11
                     /translation="MTSQPQQQLPPDDAPAGCPSSFREVPAALSVGIEEEFLLVDPVSR
                     TLRPEGPQVADSAADELGHRVGTELTRYQVEGRTEPHTCLNEAVAELRTVRAGLARAAA
                     ERGLRIASSGSPITGPVAPVPLTPGPRYAESMSLFRALDDEQSACACHVHIGVADPREA
                     IEVSNHLRPWLATLTALAANSPYWEGRDTGYASWRTIAWGRWPVAGPPPYFDSPAHFED
                     LVDELILTRTVLDRGGLYWDVRPSHHLPTVEVRVADAALTPEDTVLLAAVVRALVATAL
                     EAIRAGEPAPRPGPEILRAASWRAARDGLAGQALDPITRRLVPAAAQVERMLRALSPAL
                     RHSGDLDLVRSQWRRLRTQGSGADRQRAAYRHRSSLHDVVDHVIGATCSSGRAADGFRA
                     GSARAEIRRPG"
     misc_feature    complement(31619..31621)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            31801..32424
                     /locus_tag="IE189_RS36865"
                     /old_locus_tag="GCM10010496_74960"
     CDS             31801..32424
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003969902.1"
                     /locus_tag="IE189_RS36865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_74960"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_189928228.1"
                     /transl_table=11
                     /translation="MTGPPDVGHDDHEHHHDDSSAIAQSLRRPEVFAVLYDRYAADVHR
                     YVMRRLGDAAADDLTADTFLVAFRARSRYDLTRTNARPWFFGIAAILISKQRRTEERAL
                     RALARTGHDPVTESWVDHADDRITAQAVHRLLAGALASLSGGDRHVLLLVAWADLSYQE
                     VAEALAIPVGTVRSRLNRARRKVRSALGDDPTLVQDFAPEAGHG"
     gene            32417..33346
                     /locus_tag="IE189_RS36870"
                     /old_locus_tag="GCM10010496_74970"
     CDS             32417..33346
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE189_RS36870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010496_74970"
                     /product="hypothetical protein"
                     /protein_id="WP_189928230.1"
                     /transl_table=11
                     /translation="MDEMTTLKNFRPDAPACDRARLVPGRQRLLDAAAAQRRRRRFWPR
                     AGWKLAAAGAAAGVAVAAVLVAQVMPTNHTHRVEAEYATSPEPADGQWLYQKTLTRQST
                     LNFRDDLNPVPEKGAPAYAEFTQETWTQYGSGKTRRMLMQGGLDSVVGKAVAGSPKELR
                     RKVQKLPSEPQLLLRSLSKIIRHGGDYERIAYTFSSADTIPFEVRISLFRALETIPGVV
                     VRPQLVKDALGRPALAVHPTDDNSFTRQTHRREELLLDPKTYEYRGERTMMLAGGVIDS
                     KVTTEETLISVSAVQRFAAAVDEPGVRP"
     gene            complement(33407..34123)
                     /locus_tag="IE189_RS36875"
                     /old_locus_tag="GCM10010496_74980"
     CDS             complement(33407..34123)
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009063214.1"
                     /locus_tag="IE189_RS36875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_74980"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_189928232.1"
                     /transl_table=11
                     /translation="MPRDEGADAPGISPEQLWLSPARPRRGRKPAYSREAITAAAVALA
                     DAEGLEAVTMRKVAAQVGAGAMSLYSYAPDKETLLELMVDHVSGELPTTGTPTGDWRTD
                     LKAIARLQRAHMLRHPWLPAALAARRIPGPNTLAFLERALAALRPSGLDGAAKLEVFAQ
                     LTAFVAGHVAHEIARTAASQSPDRAAAEARYLAAVAADGRHPELAEALAAPGRPLTPEA
                     TFTRFLNRLIDGLDTD"
     gene            34300..35916
                     /locus_tag="IE189_RS36880"
                     /old_locus_tag="GCM10010496_74990"
     CDS             34300..35916
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018547919.1"
                     /locus_tag="IE189_RS36880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_74990"
                     /product="CocE/NonD family hydrolase"
                     /protein_id="WP_189928234.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 3.2e-07, bitscore:
                     22.4, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRATWRGLPAGRHDVGWEPGLPVPAADGSQLITDHYFPRAEGDFP
                     TLLVRSPYGRGLPWSPMYGVLFAEQGFHVVLQSCRGTGGSGGEFDLWRNEVADGRATVS
                     WLREQNWFDGRLGTVGPSYLGYVQWALAVDPPPELKAMVVQVGLHDPHALFHAQGALRL
                     ENALAVGVGMTYQHQGMRAFLTATLRLHRRLRDVVTAQPLRGAYVTALGGDVPWLDDVM
                     SHPEAEDAYWQGASLATVAERLDVPTGLITGWHDALGDQTFEQYRRLREAGCRTALLVG
                     PWTHTSALQQGWPEVFAESLAWLRAHLYGDRSGLRPTRVRVHVGGEDDWRDSDDWPPAA
                     AVNPWFPTAQGHLTRQAPTDSAPLTSFRYDPGDPTPSLGGPLLSRTAGPRDNRTLETRD
                     DVLTFTGPPLTEPVDILGPVSARLSISTDTGHADVFTRLCDVDAQGRSVNICDGLGRLR
                     TAGQAPSHITVPMSSTAHRFAVGHRIRWQISGGAHPRYTRNPGTGESPMDATTFTPVRI
                     TLHADSALMLATPRAARSPRD"
     gene            complement(35968..37170)
                     /locus_tag="IE189_RS36885"
                     /old_locus_tag="GCM10010496_75000"
     CDS             complement(35968..37170)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981812.1"
                     /locus_tag="IE189_RS36885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_75000"
                     /product="CdaR family transcriptional regulator"
                     /protein_id="WP_189928332.1"
                     /transl_table=11
                     /translation="MAAALHARLPELGERIARRIRSDVEAYDEESLIPFDSLRSSCTAN
                     ADLVLSHLERADAPDASPARETGRVRAEQGVPLADTLHAYRVGFEQLWTEILLESRTHP
                     GVTDDQLVSQSAEIWSLFGLYAEAVAAAYRETSAELTSQGRARRSALVEALFTGVMADR
                     STLWEAARELGLPEHGPYAVAAATAAVPGQEPLAGVEAALRRARLPSAWRLLPDHRIGL
                     VALPTAEAESTFLRVLRGTQSRVGVSPSFPSLRDTPQALRFARLALAGLREARAGVARF
                     DDDPLAMVVAAAPAEAAHLVGVVLQPLIDLPVAERARLLDTLEHWFAAAGSATEAARTL
                     FVHPNTVRYRLRRIEELTGRSLSDPRALSEIGVALLAARDPGATRPARTPPPPPGPAPA
                     R"
     gene            37335..38819
                     /locus_tag="IE189_RS36890"
                     /old_locus_tag="GCM10010496_75010"
     CDS             37335..38819
                     /NRPS_PKS="Domain: AMP-binding (9-399). E-value: 1.1e-118.
                     Score: 388.3. Matches aSDomain:
                     nrpspksdomains_IE189_RS36890_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656031.1"
                     /locus_tag="IE189_RS36890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_75010"
                     /product="long-chain fatty acid--CoA ligase"
                     /protein_id="WP_189928236.1"
                     /sec_met_domain="AMP-binding (E-value: 4e-126, bitscore:
                     413.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANLAQYLVETAQRQPGRPALRLGEHVTTYAELDERSARAAALLR
                     AQGVRPGDRVALMLPNVPEFVVLYYGVLRAGGIVVPMNPLLKTRETAYHLEDSGAVLLC
                     EWHLAPGEGAQGAEAAGVRHLAVEPAAFAALLAGHEPVREVADGVDDVAVLLYTSGTTG
                     RPKGATLTHSGLRHNTEVNAVHVQRITPDDVVVGCLPLFHIFGQICTMSVAVRAGASLT
                     LVPRFEPQAVLEAIARDRATVFEGVPTMYAALLQHPSQADVSTLRMCISGGASLPVEVL
                     HGFERRFGCAVLEGFGMSETSPVVTFNHPDRPRKAGSVGTPIRDVEVRLLDAEGRDVAP
                     GEVGELAVRGPNVMRGYWNRPEETAATVQDGWLRSGDLARRDEDGYLYIVDRKKDMIIR
                     GGYNVYPRELEEVLHEHPAVALAAVVGLPHTHLGEEIAAAVVLRPGARATPDELREFVK
                     SRVAAYKYPREVWLVDALPTGPSGKILKREITAPAG"
     aSDomain        37362..38531
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS36890_AMP-binding.1"
                     /evalue="1.10E-118"
                     /label="IE189_RS36890_AMP-binding.1"
                     /locus_tag="IE189_RS36890"
                     /protein_end="399"
                     /protein_start="9"
                     /score="388.3"
                     /specificity="substrate consensus: bOH-Tyr"
                     /tool="antismash"
                     /translation="ETAQRQPGRPALRLGEHVTTYAELDERSARAAALLRAQGVRPGDR
                     VALMLPNVPEFVVLYYGVLRAGGIVVPMNPLLKTRETAYHLEDSGAVLLCEWHLAPGEG
                     AQGAEAAGVRHLAVEPAAFAALLAGHEPVREVADGVDDVAVLLYTSGTTGRPKGATLTH
                     SGLRHNTEVNAVHVQRITPDDVVVGCLPLFHIFGQICTMSVAVRAGASLTLVPRFEPQA
                     VLEAIARDRATVFEGVPTMYAALLQHPSQADVSTLRMCISGGASLPVEVLHGFERRFGC
                     AVLEGFGMSETSPVVTFNHPDRPRKAGSVGTPIRDVEVRLLDAEGRDVAPGEVGELAVR
                     GPNVMRGYWNRPEETAATVQDGWLRSGDLARRDEDGYLYIVDRKKDMIIR"
     CDS_motif       37791..37850
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS36890_0001"
                     /evalue="2.00E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="IE189_RS36890"
                     /protein_end="172"
                     /protein_start="152"
                     /score="23.4"
                     /tool="antismash"
                     /translation="AVLLYTSGTTGRPKGATLTH"
     CDS_motif       38352..38432
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS36890_0002"
                     /evalue="1.00E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="IE189_RS36890"
                     /protein_end="366"
                     /protein_start="339"
                     /score="40.2"
                     /tool="antismash"
                     /translation="PGEVGELAVRGPNVMRGYWNRPEETAA"
     misc_feature    complement(38928..38945)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.94"
                     /tool="antismash"
     gene            38958..39650
                     /locus_tag="IE189_RS36895"
                     /old_locus_tag="GCM10010496_75020"
     CDS             38958..39650
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018568567.1"
                     /locus_tag="IE189_RS36895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_75020"
                     /product="1,4-alpha-glucan branching protein"
                     /protein_id="WP_189928238.1"
                     /transl_table=11
                     /translation="MAVIHRTVLEPTKLELLAAWLPTRPWYVPGAGGPELTKAGGFRLD
                     DPQGEVGIEFMAVTDTAGDDAVTYLVPLTYRGAPLAGAEHALVGTMEHGVLGRRWAYDG
                     CHDPVLRTQLLALLRGRVLAQDQNTSDTPDREVTRSYDGDGGDLADLAAGAVDDREGTR
                     LSAGRGSTLFLHRVLRPAPDGPPSLPPGTNGHVAGSWRTPDGSRARGLFVVLRSGPGDR
                     YGRTGRPA"
     gene            39728..40021
                     /locus_tag="IE189_RS36900"
                     /old_locus_tag="GCM10010496_75030"
     CDS             39728..40021
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006382927.1"
                     /locus_tag="IE189_RS36900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_75030"
                     /product="hypothetical protein"
                     /protein_id="WP_189928240.1"
                     /transl_table=11
                     /translation="MAQKKDHVESVRAVRQLRRVRPLYAGGALLWAASAAWTGWDEPGS
                     RQMWVSVLFLVVFTGLLSVTSVWLSRQRAAGAGRSVHHAAPRRAFANRHASA"
     misc_feature    complement(40196..40210)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.31"
                     /tool="antismash"
     gene            40243..40701
                     /locus_tag="IE189_RS36905"
                     /old_locus_tag="GCM10010496_75040"
     CDS             40243..40701
                     /NRPS_PKS="Domain: Polyketide_cyc2 (3-146). E-value:
                     2.3e-13. Score: 42.7. Matches aSDomain:
                     nrpspksdomains_IE189_RS36905_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020126584.1"
                     /locus_tag="IE189_RS36905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_75040"
                     /product="SRPBCC family protein"
                     /protein_id="WP_189928242.1"
                     /transl_table=11
                     /translation="MAGQFEATVEVDRAVEEVFAYLADGRNDPQFSPRVLRIDRTPDTP
                     TAVGTVFRSTVKDAGMKTAREFRITAFEAPVRIRWQEASKNSVTVREGGYDLERLTDGR
                     TRVRIFNSLEGHGVGKLLVGLALAAARKDADAFGARIKAAAEAAIPAR"
     aSDomain        40252..40680
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS36905_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="2.30E-13"
                     /label="IE189_RS36905_Polyketide_cyc2.1"
                     /locus_tag="IE189_RS36905"
                     /protein_end="146"
                     /protein_start="3"
                     /score="42.7"
                     /tool="antismash"
                     /translation="QFEATVEVDRAVEEVFAYLADGRNDPQFSPRVLRIDRTPDTPTAV
                     GTVFRSTVKDAGMKTAREFRITAFEAPVRIRWQEASKNSVTVREGGYDLERLTDGRTRV
                     RIFNSLEGHGVGKLLVGLALAAARKDADAFGARIKAAAE"
     gene            complement(40742..40915)
                     /locus_tag="IE189_RS36910"
     CDS             complement(40742..40915)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676958.1"
                     /locus_tag="IE189_RS36910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_189928244.1"
                     /transl_table=11
                     /translation="MSLFLFLILLALVLGIIGFAVHGLFYLLIIGAVVLVADLCYVGLR
                     FRRGGRRHRIAR"
     gene            complement(40939..41295)
                     /locus_tag="IE189_RS36915"
                     /old_locus_tag="GCM10010496_75050"
     CDS             complement(40939..41295)
                     /GO_function="GO:0042314 - bacteriochlorophyll binding
                     [Evidence IEA]"
                     /GO_process="GO:0019684 - photosynthesis, light reaction
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009062940.1"
                     /locus_tag="IE189_RS36915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_75050"
                     /product="PRC-barrel domain-containing protein"
                     /protein_id="WP_189928245.1"
                     /transl_table=11
                     /translation="MVEASDIREWRGHDVVDAQGHRIGVLESVYVDTGTDLPSFATVTV
                     GLPTRRRLVFVPLLGATVGPGYLKVAHDKNAVKKAPSIDTDGELLAPDEPKVFAHYALD
                     YAPGAGGERRLARR"
     misc_feature    complement(41275..41286)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.29"
                     /tool="antismash"
     gene            complement(41355..43340)
                     /locus_tag="IE189_RS36920"
                     /old_locus_tag="GCM10010496_75060"
     CDS             complement(41355..43340)
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004003755.1"
                     /locus_tag="IE189_RS36920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_75060"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_189928334.1"
                     /transl_table=11
                     /translation="MLRELLPIALWREDSDGRIVEWSLAAQDLLGHRPQDVLGRAAAAL
                     LVPEGRHELADQLTYRVQGGETVVGTLAVRHRDGHEVTMEMWIVPAADARGRTGALLIA
                     VETSQVLRMRDSLAALESLFSQSPIGLATLGTDLRFLRVNDALARMNGVSAAAHTGRRL
                     TEVVPGVNAVALESTMREVLDGGKAVVDVRRTGRTPADPDRERTWSCSYAPLVDGAGRT
                     LGLIASLIDITESQRAEHEAARARRRFALLAEAGTRIGTTLDLRQTSEEIVRMLVPQLA
                     DSADVQLLEEVLAPDESTAATHGVVRRMAALFPDPSAPTARLLPGMTSRIARGSLYERV
                     IADGRPTDLYRSDVPALVTDPRADELRAYLMGLGSARLIPLVARGKVLGAVVVTRLRSR
                     EPFDEQDSVLIDELAARAALNIDNALMYTRQRAAALTLQRSLTNSALPAVPGLELTGRY
                     LPASEHDVGGDWFDVIALPEGRTGLVIGDVMGHGVHAAALMGQLRTAVRALARHDVDPA
                     RLLRSLDTVVADMGEDQMATCVYAVHDPASGGCLVARAGHPPPAVVPPGGPPAFLDGSP
                     GTPLGTGGRQFRTERIPLPPGSVLVLYTDGLIETRAADLDQGLDRLARALRFPGQPLAA
                     LCDGVLGEMLPHPAQDDVAVLMARPL"
     misc_feature    complement(43536..43545)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
ORIGIN
        1 gaccgtcata ggtgagtggg tcaaggaggc ggatgtcctc gacggtggtt actggtatcg
       61 gaacctgcgg agccaggtcc gtttcggtcc cgcgatcgcc gacctcctgg gtgagggtta
      121 ctcggtgttc gtggagtcga gcgcacaccc ggttctggtg cacccggtca gcgagatcgt
      181 ggacgaggcg gatgacacgg tccggctgcg tgctgtcgtc gctggttcgc tgcgccgcgg
      241 ggagggcggc ccgcgccgac tgctgacgtc gattgcggag ctgttcgtgc ggggcgtccc
      301 tgtcgactgg gcgggtgtcc ttccggccgg tgccgctgcc gctcacgtgg aactccccac
      361 gtatgccttc gatcacgagc gttactggct gcgttctgcg cctgctgtgg atgctgtcgc
      421 gttgggtcag gtgggtggtg atcatccgtt gatcggtgcg gtcgtgggtc ggccggactc
      481 gggtggtttc ctgacgactt cgcggtggtc ggtggaggcg tatccgtggc tgggtgatca
      541 cgtcgtcggt gaggtggtcg tggtgccgag tgcggtgttg gtggagttgg cgatccgctt
      601 gggtgacgag gtgggctgtg cggtggtcga ggagttgagt gtggaccggc ccgtgctgtt
      661 gccgttgcgg ggtggcaggg cggtgcagat gaccgtgggg gaggcggacg ggcaggggcg
      721 gcgggcggtc gaggtgttct cccgtgcgga cgatgccggc ctggaggggg tgtggacccg
      781 tcacgcgcac ggcatgttgg tgcccggccc ggtgacgggg tccccgtcgg cttccggcgc
      841 ggtgtggcct gacggcagcc ccgcagccga ggtggccctg gacagggcgg tgagcgacgc
      901 cgaccgctac ggcctgcatc cggcgttgct ggacgcggcg gtgtgcacgg tccttccgcc
      961 gggcatgatc gtgacccggt ggagcggggt cgccttgctc gcttccggtg cggcagcggt
     1021 ccgggtacgt gctgcccgtg acgcggcagg ggtgagccgt cttgagctgg tggacgccac
     1081 ggcagctccg gtactgaccg ctgacgccgt tgtcgccgag ccgttccagc cgccctcgcc
     1141 cgaacacgcc gagaccacgg acacatcggt cgtccgtgcc ggccgtcgga ccactcggca
     1201 ggtggcagcc tcccgcctgg gcggcctcgc cgaacagctg gccgccacgc ctccggttca
     1261 gcgggagcag ctgctgctgg atctgatccg gcgcgaggtc gcctcggtcc tgggccattc
     1321 ggcacccggc aaggtcgacc ccgaccgggc attccaggag gtcggcttcg actcggtgct
     1381 ggccgtcgaa ctccgcaacc gactcaccgg actcgtgggg atccgccttc ctgccacgat
     1441 catcttcgac catcccaccc cccggggcct gatgcgccgg ctgctcgcgg aactgtgccc
     1501 cgacgccgtc ggcgagttgg cgggtcggga ggacgagatc cgcagggtcc tggtcagcac
     1561 gcctctgtcc cggttccagg aactcgggct catggagaag ctcctgcacc tggtggcgag
     1621 ccccggtggt gaaggtgcca cggcgccgga caccgccgga ccggagcagg acgccaggct
     1681 gctgatcgag gagatggacg ctgacgatct ggtggagcgg gcgatgagga aagccgggaa
     1741 gcagtagcgg acccacgacc ggaacgaggg gagacaggga atgaccagct cagaggaaaa
     1801 gcttgtcgag gcgctgcggg cttcactgat cgagaacgag cggctcgaat ccgagatcaa
     1861 gaagatccgc gacagctccg atgaaccgat cgccatcgtg ggcatggcgt gccggttccc
     1921 cggtggggtg tcctcccccg aggagttgtg ggagttgatc gccgatggcc gttccgcggt
     1981 cggcccgttc cccaccgacc ggggctggga tcttgagaac ctgtacgacc cggacctcga
     2041 tcgcaccggc accacatatg tacgcgaagg cgggttcctg cacgacgtgg gcgagttcga
     2101 cgccggtttc ttcggcatct cacaaagcga gacgctggtc atggacccgc agcagcgtct
     2161 gatgctggag acgtcgtggg aggcgatcga acgggcgggc atcgacccgg ctgctctgcg
     2221 tggcaggaac gtcggggtgt tcgccggcgt gggcggacac gattacgcca ccggtttcca
     2281 cagcgtcccc gacgagctcg agggctacct gatgaccggc ggtttggcga gcgtcctgtc
     2341 gggacgggtt tcctacacgc tcgggttcga ggggcccgca gtcacgatcg acacggcctg
     2401 ctcgtcgtcc ctggtagccc tgcacatggc agtacagtcc ctgcgttcgg aagagtcgtc
     2461 gttggcgctg gccgggggct ccagcgtgat gtgcactccg gctggcttgg tgttggcctc
     2521 gcgtatgcgc agtcttgcga cggacggcca gtgcaaggcg ttcgcggcat ccgcagatgg
     2581 aacgaactct gccgagggcg tgggtgttct gctgttggag cgggtttccg atgccatccg
     2641 tgacggacat gagattctcg gcgtcgtacg ggccaccgcg gtgaaccagg acggcgcgtc
     2701 caacggactt accgcgccga acgggccgtc gcagcagcgg gtgatccgcc aggcactcgc
     2761 ttcggctggt ttgtcgtccg ccgatgtcga catcgtcgag gcgcacggca ccgggacccc
     2821 tctgggcgac ccgatcgagg cacaggccct gctcgccact tatggtcagg gccgtgaccc
     2881 cggactgccc ctgtggctcg gttcggtgaa gtcgaatctt ggacacgcgg gccatgcggc
     2941 aggcgtcgcc ggtgtgatca agatggtgat ggccatgcgg catggtgtgc tgccgcggac
     3001 tttgaacgtg gacgagccca cgcctcaggt ggactggtcc acgggagctg ttgagctgct
     3061 ggccgaggcg cacgagtggc ccgagaccgg ccgtcctcgt cgtgcggggg tctccggctt
     3121 cggcgtcagc ggcaccaacg cgcacgtcat cctggagcag gcgcccgagc agacatccgt
     3181 gaccccgccc gacgggaagg cgcgtgtgct gggcgactcg gtcgtgccgc tggtcctctc
     3241 ggcccgtggc gaggcgggcc tcgccggcca ggccgggcgc ctcgcttcgt tcctggggca
     3301 acgtcaagag ctggacctgc tcgacgtggg ccggtcgctg gtgcggagcc ggggtcttct
     3361 ccccgaccgt gcggtcgtgc tcgccgagga ccgggaagag gcgctggccg cattggacgc
     3421 cgtggccgcc ggggagtccg cgaccggagt cgtcagggga acggccgaga gcgtggtggg
     3481 ccggaccgtc ttcgtgttcc ccggccaggg ctcgcactgg gcgggcatgg ggagggaact
     3541 gctcgaggcg tcgcccgtgt tcgcgacgcg catggccgcg tgcgccgagg cgctcgaccc
     3601 gctgaccggc tggtcgttgc tcgacgtggt gcggcaggcg gagggcgccc ggtccctgga
     3661 cgacctcgac gtcgtgctgc cggtgtcgtg ggcactgatg ttgtcgctcg ccgcgctgtg
     3721 ggaagcgtgc ggggtcgtcc cggacgcggt cgtgggccat tcccagggag agatcgccgc
     3781 tgcctgtttt gccggtgcgc tgtccctccc ggacgccgcc cgcctcgtgg tctaccgggc
     3841 cgaggccatc cgcgccgagt tgtcgggacg cggggggatg gcatccctcg tcgccggggt
     3901 caaggccgtg tccgtgctgg tcgaggaatg gccgggcctg gagatcgccg cggtcaacgg
     3961 accctccacg gtggtcgtgt ccggtgaact gcccgccctg gaggagctgc tcgcccggtg
     4021 ccggaccgag ggcatccacg cccgcaggat tctcggggcc aacgccgccg ggcactcctc
     4081 acagatggag gtgctccgcg agtccttcct cgaggcgatt gctgcgatcc cctgcgggcc
     4141 ttcgcgtgtg ccgctctact ccacggtgac cgggcgactc caggacacca cggaactgga
     4201 cgccgagtac tggtaccgca acctgcggca gaccgtgcag ttcgacccgg ccgttcggac
     4261 cctggccggt gaaggacacg gggtgttcgt cgagatcagc tcgcaccctg tgctggcgca
     4321 gagcgtccag gacgtgctgg aggagctcca ggcacccgct gtcgtcaccg ggacgctgca
     4381 ccgcgacgag ggcgggcccc gcaggttcct cgcctcgctg gcccatctgc acacccacgg
     4441 cgtccggatc acctgggaga ccgtcctcgg cagcggtacg gagcggcccg tggatctgcc
     4501 cacgtacgcc tttcagcgtc ggcgctactg gctggacgcg gcggacgccg gcggcgacgc
     4561 accgggcctc ggtctcgacg cggcggacca tcccctgctc ggcgcggtca ccgagatccc
     4621 cggctcggac ggcgtgctgt tcacgtcccg gctctcgctg cgcacgcacc cctggctcgc
     4681 cgaccacgcg gccgccggaa tcgtcctcgt gcccggagcg gccttcgtgg aactcgcggt
     4741 ccgcgccggc gacgagatcg ggtgcggcct ggtcggcgaa ctggtcatcg agcgccccct
     4801 gctgctgccc gggagcggcg gtgtccaggt acgcgtgtgg gtgggcgagc ccgacggatc
     4861 cagccaccgc accgtccaga tccactcccg ccgggaggaa gccggtccac gggggagctg
     4921 gacccgtcat gcctgcggac ggctggtgcc ggaggagggc ggggccgatt tcgacctgac
     4981 ccggtggccg ccgcccggcg ccaccgccgt cgacccggac gccctcgccg acgcctacga
     5041 cggcatggcg caggcgggat acggctacgg tccggccttt cggggcctgc gccgggcgtg
     5101 gacgcgcggg gaggacgtgt tcgccgaggt ctccctgccc gaggcagcgg gcaagggcga
     5161 tcactacggc ctgcacccgg ccctcctgga ctccgccatg catgcctgtg ccttccgcac
     5221 cgacatggca ggtgagagcc cgaagctcgc tctgccgttc gtctggcgcg atgtcagact
     5281 gcacgccgcc ggaacctccg cactgcgggt ccacctcaca ccgctcgccc tcgacacgat
     5341 ccgcttgcgc ctggccgacg cctccggcgc acccgtggcc gccgtcgact cgatggtcct
     5401 gcggccggtg gtcccggagt cgctgcgtgt cggctcagga gcgtcccagg agcagatgtt
     5461 ccgggtggcc tgggagcccg tctccgtcag gagcgtgcgg gacgagcccg acgtcgcacg
     5521 cgtgacgact gccgaggacg tccgtgccgt ggccgcaacg ccccccggca tgctcctcct
     5581 cgatgtgtcc ggcaacggac gaacggacct cgccgccgtc cgggacctca ccgggcgcgt
     5641 gctgaaggtc gtccgggcat ggctcgcgga acccgccttc cagggcgttc ctctcgtcgc
     5701 tctcacccgg gccggtgccg tcgtccggga cggggacccg gttcccgatc cggccgtcgc
     5761 agcggctgcc ggcctgctgc gttcggcgca gtccgagaac ccgggccgca tcgtcctggt
     5821 cgacacggac ggcacgcagg cgtcagcccg gcgcctgccc gacgtactcg cgtccgggca
     5881 gcctcaggcg gcactgcgcg gcggcgcggt ggcggtgccg aggctcgtca aggcagcccc
     5941 cgccgatgcc cctggccgtc cgctggaccc cgagggcacg gtcctgatca ccggcggtac
     6001 gggccggctc ggtcgcctgg cggccacgca cctggtttcc aagcacaaga tcagaaacct
     6061 cgtcctggtc agccggaggg gcccggacgc accgggcgcg gccgagttgg aagccgaaat
     6121 cgaagggctc ggcgcgttcg tccggatcgt ggcgtgcgac gtgtccgacc gggactccat
     6181 ggtcgcgctt ctggcctcgg ttcccgagga cgcccccctc accggcgtga tccacacagc
     6241 cggcgcgctg gatgacggcg tggtgacgtc cctgacgccc gaacggctcg acgcggtgct
     6301 ccgcccgaag gccgatgcgg cacgcatcct ggacgaactc acgcgcgatc tcgacctcgc
     6361 ggccttcgtc ctgtactcct ccctttcggg gatcttcggt tcagcggggc agggcaacta
     6421 cgctgccgcg aactcctacc tcgacgcgct ggccgtacgc cgtcgtgccg ccggactgcc
     6481 ggcgacctca ctggtgtggg gttggtgggg gcggggatcg ggcatgctgg acgaactcga
     6541 cgaggccaac ctgaagcgtt tcgaccgctg gaacaacgcc gaactcacgg cgcaggaggg
     6601 catggagctg ttcgacctcg cgctgctcca ccgtgacgcc gttcaggtcc tggcgaagat
     6661 ggaactccac acgcccgggg accggaccga ctccgcgtcc gtccccccac tgctgcgcgg
     6721 cctcgtccgg gtcggccggc ggcccgcccg tgagggggcg accggggccg acaccctggc
     6781 ggaccggctg gccggggcgg ccccggacca gcgagggaag atcctggtcg acctggtcca
     6841 gcgcgaggtc gtcgcgatcc tcggctacgt ctctgcggac gaggtcggac cggacacctc
     6901 cttcttcgac atcggtttcg actcgctgac cgccatcgaa ctcaggaacc ggctgtcggc
     6961 gctcaccggc gtccgcatcc cggccacctt cgccttcgag taccccaccg cggaactggc
     7021 cgccgaggaa ctgggggaac ggctcgaact ccccatgggc tcgccggaca cgtccgggac
     7081 gtgatcgaac gccggaccgg cgcaccggtc accgacccac cccctccgcc cctcgccgac
     7141 gaagaacacc caaggagaca cagcatgttc gacaaggaca agtacctgga acacctcggc
     7201 ttctcgggaa cgcccgacgc gagcctggag accctgcgga agatccaccg cgagcaccag
     7261 atgcggatcc cctacgacag tggttacgcc ctggccctgg acagcagcgg tgacgccctc
     7321 ggcctggccc aggcgcattt cgacctcgac gcggccttcg agacgatcgt gctcagcggc
     7381 cggggcggca tctgcgtcga gttgaacttc atgttccatc gcctcctcgt cgagttgggc
     7441 ttcgaggtgc aggtactggc cgcgagcacc ctcctgccgg gaggagtgtg gggccctgag
     7501 gtcgagcaca tggtcatgcg cgtcaccctc gacggcgagg actggctcgc cgacgccggg
     7561 cacgcgggca tctccatcgt ggagccgctg ccgttctccg gagagaccgt cgtccaggac
     7621 ggcatcgagt tccggctgac gcgacgggag gagtactact tcctcgagta caagacccgc
     7681 gccaaggact ggcgcgactc ctaccggttc ctgccggaga cacgtaccac cgcggactgg
     7741 gcccgctggc gcgacgccct gccggtggaa gagctggtgg cgcacccgcg gcgccgccga
     7801 cgggtcatcg acaacgggca ggtcacgctc accgcgaacc tcttcgtgtc cgtcgaggac
     7861 ggcaaggagc ggctccgtct catccgggac gagaacgaac tcgagaagat cgtcggcacc
     7921 tactggcgct gagctgacga gacagcggcg gggtggccgc cccggcgcgg caccggcttc
     7981 cacaggacgg agtgaggcgg agtgagagaa cagataccgg gccacgtcct ggagccggcc
     8041 gtcggctctg cgctccggca cgccgggacc gccggggttc cggagcgcat gccacggcgg
     8101 ccattcgggc aactcaccgg tccggcatgc ctccatggaa cgggagcccc gccggcatga
     8161 cgcgctcgtc agaggccgcg cacggcgagg tccggggcag gaacacgcgg gacgcgaggc
     8221 tcgcggaccg cctcgccgcg gccctggacc gacccgcggc gcagcagccc gagtggccgg
     8281 acccggcccg ggcccggacc gtcgtggaac tgctgcgcac cgcacccccg atcgtcgccg
     8341 agccggagac ggcacagctc tccgagcggc tcgcggcggt cgcccgcggc caggcgttcc
     8401 tgttgcagag cggggactgc gcggagacct tcgccgagac caccgcatcg cacctgcggg
     8461 ccaacctcgg tctcctgaag cgcatgtcgc tgctcctggc ccgcgccgcc gggctgccgg
     8521 tggttcccct cgcccgtatg gccggacagt acgcgaagcc acgctcccgg tccgtcgacg
     8581 cggacggcct gccggtctac cggggtgaca tggtcaactc cgccgaaccc acccttgccg
     8641 cacgcacgtg tgacccggac aggatgctcc acgcccacga gcacgcggcc cgcgcgatga
     8701 cgctggcccg ccgggcgtac gcgcgggagc agtcgaaccc gcgcaccggc ccctcctcgt
     8761 acccgcacgg cacggccggc ggccgcctcg tcggcacggc cgaggagacc ggccgggacc
     8821 agggcccgag gagcgaacag atctatgtgg gccacgagat gctcctgctc gactacgaat
     8881 gcgctccgct ccgcgccgcc gggctcacca ccggcccgga gccgctgctc gtcagcccgc
     8941 tcgcgcactt cctctggatc ggcgagcgca cgcgaggcct cggcgacgcg cacctcgccg
     9001 tcgccgaact gctcgccaac cccatcgggg tgaagatcgg ccccagcacg accccggaag
     9061 aagccgtcga gtacgtccgc aggctcgacc cccatgccac gcccgggcgg ctgacgctga
     9121 tcagcaggat gggccgctcc caggtccgcg aggtgctgcc gccgatcgtg gagaaggtca
     9181 cctccaccgg ccaccaggtg gtgtggcagt gcgacgcgat gcacggcaac tcccgcacga
     9241 cgccggacgg ccgcaagacc cgccacttcg acgacatcgt cgcggagatc gagggattct
     9301 tcgaggtcca ccgcagcctc ggcacccacc cgggcggcct ccacctggag gcgaccggcg
     9361 aggacgtcac cgagtgcctg ggcggggccc gcggcctcgg tgaggccgac ctgccggccc
     9421 gctaccgtac cgcctgcgac cctcgcctga acgaggagca gtccatggaa ctggccttca
     9481 ccgtcgccga tctgctcgcg gaggccatgc ggccggctgg gaccggatcg ccgtgaccgg
     9541 cccggtcctc gtgcgagttc ctccgcccgc gcgcacccgg aaccggtgac gcgcaccccg
     9601 gcggacggct accagaccgg gggatgcggg gtggtcagcg cggtgcctac cgtgaaagtc
     9661 gcactcttgg gtctgctcct cgatctggaa cctccgtcgg ccacgtgccc cgcccgcctc
     9721 atgccctccg gcggccatcg gccgagaaac gtccgaagtg gagatgtgga gatacatgaa
     9781 cgcgcgaccg gcaccagagt ttccctcctg gccgcagtac gacgacggcg agcgcaccgg
     9841 cctgatccgg gccctggagc agggtcagtg gtggcgcgtg ggcgggtcgg aggtggactc
     9901 cttcgagagt gagttcgccg acttccacgg tgccccgcac gctctggccg tcaccaacgg
     9961 cacccacgcc ctggagctgg cgttgcagtg cctgggtgtc ggtccgggca ccgaggtcat
    10021 cgtgccggcc ttcaccttca tctcctcgtc ccaggccgct cagcggctcg gcgcggtcgc
    10081 cgtccccgtc gacgtcgatc ccgacacgta caacatcgac gtggccgccg cggcgtccgc
    10141 catcaccccc cgcaccaggg tgatcatgcc cgtgcacatg gcggggctca tcgctgacat
    10201 ggacgcgctc gacaggcttt ccgcggacac cggcgtgacc ctcttgcagg acgccgccca
    10261 cgcgcacggt gcccgctggc agggcaagcg ggtgggcgag ttgggcacgg tcgccgcgtt
    10321 cagcttccag aacggcaagc tgatgacggc cggcgagggt ggtgcactgc tcttccccga
    10381 cgaggagacg tacgaggccg ccttcctgcg gcacagctgc ggccgccccg tcaccgaccg
    10441 ccgctacctg caccggaccg ccggcaccaa catgcggctc aacgaattct ccgcgtccgt
    10501 gctccgcgcc cagctgagcc gcctcgacgc ccagctcacg ctgcgcgaac agcgctggac
    10561 cctgctgtcc cggctgctcg gcgagatcga cggcgtcgtg ccccagggag gcgatgcgcg
    10621 cgccgaccgg aactcgcact acatggccat gttccggatc cccggcatct ccgaggaggg
    10681 ccgcaacgcc ctcgtcgaca cgctcgtcga ggccgggctg ccggccttcg ccgccttccg
    10741 ggcgatctac cgcaccgacg cgttctggga gacggccgcg cccgacacca ccgtcgacaa
    10801 gctcgccgga agctgcccgc acacggaggc gatcagcacc gactgcgtct ggctgcacca
    10861 ccgggtgctg ctggcctccg aggaagccct ccacatcacg gccgagatcg tcgccgacgc
    10921 ggtggccgca cgatgaagct ccgcgccgcc gtcgtcgggc tcggctgggc aggccgcgag
    10981 ctgtggctca gactgctgag cgagcacgag gacttcgagg tggtcgccgc cgtcgacccc
    11041 gacccggcct cccgggcagc cgccgtggcg atgggcctgc ccgcccacac caccatggac
    11101 gccctcgact cccgcacggt cgacctcgcc gtcgtcgcgg tacccaacca tctgcacgcc
    11161 gaggtggcgg ccgccctgct ccgccgcggg atctccgtct tcctggagaa gccggtctgc
    11221 ctgaccaccg ccgaggccga cgccctcgcc gccgccgaac acagcggcgg gatgctgctc
    11281 gcgggcagcg ccgccgccca ccgcggcgac gtccagcggc tcgccgggct gctgccccag
    11341 gtcggccgga tccgccatgt caccctggcc tgggtcaggg cgcgcggcgt gccacagccc
    11401 ggcggctggt tcacccagcg cagcaagtcc ggtggcggtg tactcgtcga cctcggctgg
    11461 cacctgctcg acgtcctcac ccacctcctc ggccccgccc ccgtcaccca ggtgatcggc
    11521 tcggtctccg acgacttcgt cagcagcggt gcctggtccg ctgcctggcg cgaggaccgg
    11581 tccaccgacg tcccggccgg caacgtcgag gacaccgccc ggggcttcct gctccgcgag
    11641 gacggcatct cggtcgcgct gcaagccagt tgggcctccc acgaggcgct ggacgcgtcc
    11701 gtcgtcaccg tcgagggcag caggggaacg gcacggctgc actgcacctt cggcttcagt
    11761 cccaaccggg cccccgaacg ggtgctcacc ctcacccggg aaggcaccac agagcggatc
    11821 ccgctgcccg ccgagccgat cggcgccgag tacggacgcc agctcgacgg cctcgccggg
    11881 ctcctggccg acccgggccg acgcggcgtg gccgtcgccc aggcccgtga caccgtccag
    11941 ctcgtggaga gcttctacgc gtcggcccgc ggcgctcgcc ccacggacca cgcgccccgg
    12001 tgcacctccc accaggaggt gagtaccgca tgaccactgg gtcgcaccac catgcgggaa
    12061 cgacctccga acagcgctcc ccggtgtcca gacacgcagt cgtcttcgat ctcgacggag
    12121 tcgtcgtcga cagcttcgcg gtgatgggcg aggccttctc cctcgcctac gccgaggtcg
    12181 tcggcccggg cgaggcgccc ttcgaggagt accggcgcca tcagggccgc tacttccccg
    12241 acatcatgcg gatcatgggc cttccgcccg agatggagga gcccttcgtc cgcgagagct
    12301 accggctcgc ccggcacgtc caggtgtacg acggtgttgc cgatgtgctg aggacgctga
    12361 acgagcgcgg cctccggctg gccgtcgcca ccggcaaggc gggcgagcgc gcccggtccc
    12421 tgctcgacgt cctcgggctg cttccgtact tcgcccacgt catcggctcc gacgaggtgc
    12481 cccggcccaa gcccgccccc gacatcgtcc accgcgcgct cgaactcctc ggcgttcccg
    12541 cggaacgggc cgtcatgatc ggcgacgccc ccaccgacct ggccagcgcc cagggcgccg
    12601 acgtcaccgc cgcggccgcg ctgtggggct gccacgacgt gaccggactg ctcgccgccg
    12661 gccccgacat cgtcctgcgc cggcccgccg acctgctcgt cctctgcccg gccgtccccg
    12721 gccgctgaga cgccgcggcc gtccgcggag cctgtccgac cgaacttctc cccccatgga
    12781 ccgccgaggc gcacggggga ccgaaacgac atggggaacc gtatatgtgt tcattaagca
    12841 ttcaagaggt ctgtgcataa cgtggaggag acgacgaagg cacactcatc ccccgcacgg
    12901 atccgatggc tcaccgacga gcagcaacgc gtctggcgct ccttcgtcca cgcgaccacg
    12961 ctcctcgagg accacatgtg ccgccaactg caacgtacgg tgaacatgcc tcacagctac
    13021 tacctgctcc tggtcaacct cgcggaatcc cctcaccagc ggctccagat gtcggagctg
    13081 gcgatgcatg cgaagatcac ccggccccgg ctctcgcacg ccgtggcacg tctggagaag
    13141 gacggcctgg tgaggcgcga ggaagctccc tccggcaagc gcggcacgtt cacggtgctc
    13201 acggaggagg gcctggaggc cctcgggcgg gccgctgcgg gctatgccac ggtcgtgcag
    13261 catgccctgt tcgaccggct caccccccag cagcaggagt ccctcggcgc gatcatgcag
    13321 atcgtcaccg agggactcca gacggacagg gcgggcgccg accttccctg gctgcgctag
    13381 aagcgagacg gggaggccgg tggcggtcgg tcaggtcgtg cccggccgga ccgtgctcgg
    13441 gccggccgtc gggtcaggat cgggagggct cgtcgtaccg gtggaagccg tggcccgtct
    13501 tgcggcccag tcggccctcc tggaccatcc gcgtgagcag cgggggcagg tcgaggacca
    13561 ggccgtcgga gttctccgcc atcgagcggg ccacgtcggt gatcgtgtcg atcccgatca
    13621 ggtcgagcag cgcgagcgga cccatgggat gtccgcagcc cagcaccatt ccccggtcga
    13681 tgtcgtctgc gtcggcgatg ccctgctcgt acatcctgac cgccgccatc agatacggca
    13741 cgagcagggc gttgaccacg aacccgcttc ggtccgcggt gcggatcacc tccttgccga
    13801 gcgtgtccct ggcgaaggac tcggccgacg cggcgcactg ctgcgaggtg cggtccgtca
    13861 ccaccacctc gaccaggggc atcagcggca cgggattgaa gaagtgcatt cccaccacgg
    13921 acccggctct gccggtggcc tccgccagat cgccgaccag caggctggag gtcgtcgagg
    13981 ccaggacggc cgcagggtcg gtcagcacct cgtccaccgc cttgagcacc cgttgtttca
    14041 catcgagtct ctcggtcacg gcctccacga cgaactgccg gtccgcgagg cccccgacat
    14101 cggcggtgac ccgcaaccgg cccatggccg ccgcctgttc cggctccgtc atccggccct
    14161 tggccaccgc gcgggcgaac gcggccgtca gccgtccgac cgcgtcctcg atccggtgcg
    14221 gggcggagac caggaccgtc acctccaccc cggcgcgcag gctcacctcg gcaaggccgg
    14281 cgcccatcgt cccgccgccg accacgccca gtcgttccac cgtcgtcctc atcgggcccc
    14341 gccctcggtc ccggtccagc gcagcagggc ggcaccggcc gccatacccg cgccgaagcc
    14401 cgccagaagc accagatcgc cgtcccgcag cacgccggaa cggttggccg cgtcaagggc
    14461 caccggcacc gacgcagagc cgatgttgcc gctgtgacac aacggcagat gggtccttgc
    14521 ccgctccaga ccactggcct cggccagttc cgccaccagt cggccattgg cctggtgcgg
    14581 tacgaagtgc cgcacgtcgg ccggttggca gccggaacgc ttgagcagcc cggcgatgag
    14641 gccggggacg ttgtccagga cgaagtcgcg caccccccgg ccccgcatgc tcagcagatg
    14701 gccgccgtcc gcgaccgtct cgacggaggc gggacggcgg ctgcccccgg ccggcatgct
    14761 gatcagctcg tgggcgtcgg cccggctcac caactcgacc ttgagcaggc cgcgttcggg
    14821 gtcgccgggc gcatgcggga cggagccgac gaccgcggct ccggctccgt ccccgaacag
    14881 gacactggtc gcccggtcgc cgaagtcgat gaaccgggtc cacacgtcgc tgccgatgac
    14941 caggaccttc gtcgccgggt ccagggccac gtacgcccgg gcgatggaca gcgcggtgac
    15001 gaacccggtg caggcgatgt tgacatcgaa acaggcggcc cgtcgggcac cgagcgccag
    15061 ttgcaccagt gacgcggtgg aggggatcgg ggcgtcaccg gtcgtcgtgg cgacgatgat
    15121 gaagtcgatg ccgtccgcgt ccactccggc ctggtccaag gcggcgcgcg cggcgtggac
    15181 ggcgaggtcg gacgctgcct cgtccggtgc cgcgtaccgc cgttcgagga tggcggtccg
    15241 gtcggcgatc cacccggcgg acgcaccggg cacccgggcc tcgatctcct cgttggtcac
    15301 cacccgttcg ggcaggtagg agccggtccc cagcacggac gtgacgtacc cctgatccct
    15361 ttgcacggtc acgccgcccg cacgccgtcg tgcgcgtacg cgcgcatcag cgtcagtcgg
    15421 tcctcgccga tccgggcgcg ccgctctggg tcggtcacac ccagacccgg acggtcggcc
    15481 agacagagca cgcccacctt gccgatgtgc tggttgagct gcaccagccg cgtcgcctcg
    15541 ccggtctcct ccagcgggaa cagcgaggtc agtgcgggca ccagcgaccc ctggtcgaac
    15601 agtcgcgcgg tgtcgacctg ttcctggagg ttcgccacat ggctgccgac gatgcgcttg
    15661 agccgcatcc acagatagcg gttgtcgaac cggtgctggt agccggtgct cgaaccgcag
    15721 gtcaccacgg tgcctccgcg ccgcgcgagg aacaccgaga taccgaaggt ggatctgccc
    15781 acgttgtcga agacgatgtg cggatcctcg cccacgccgt cacggatgag ccggcccagc
    15841 cgcttcccct gcgccaccgc gacttcgggc tcgtcgtcgg tgtcaccgcc gaagtcgtgc
    15901 tcctgacggt taatcaccag gtcgcagccg agggcgcgcg ccgctcgcgc cttctcctcg
    15961 gagccgacga ctccgacggc gatgccgccg ccgttcttca ccaactgaac ggcataggac
    16021 cccagtccgc cggacgcgcc ccagatcagg accacgtcgc cctgcttcat ccgtgcgccg
    16081 cggtcgctga ccagcatccg gtaggcggtt ccgccgcagg ccgggatcga ggcggcctcc
    16141 tcccaggcca ggtgtgccgg cttggggatc aactggctgg cccgggcgat ggtgtagtgg
    16201 gcgagaccgc cgtagttggt ctcgaagccc caggcgagct ggttctcgct gagcatcccg
    16261 tcggcctgga cggacgcctc ctgatcctcg acacaggccg cgttgaccag cacgtggtca
    16321 ccgacccgcc agcgccgcac accggaaccg gcgcggacga tcactccggc ggcgtccgag
    16381 ccgaggacgt ggaacggccg gtcgtgccgc ttcgcccagc cgccctggcg cccgtaggcc
    16441 tggaggaagc cgaaggtcga cagcggttcg aaggtcgcgg accagaccgt gttgtagttg
    16501 atggagctgg ccatgacggc gatcagcacc tcgtcgggcg cgagttccgg catcggcacc
    16561 gcgcccacgt ggagggtgtt gcgcacgtcg cggtcgcctt cgatcccctc gaaggtcttc
    16621 tcgtcctcga tccgcaggtg cgcggcgagg aactccgcag gtacttccgc ggcggccagt
    16681 tcccgcggcc cggcaccggc acgtactgca tcggagagtg acatcatcgg gctcctcgtc
    16741 aagccgtgtg aggctggtgg aacgatcggt ttgcgcaggc cggcggtggc tggagaaggc
    16801 cggtgcgagg acggcgggga ccctggtccg cagaggttcc ggctgcgcct ggtccaccac
    16861 gccgccgggc cggagcaggc ctgcgacgcc ggcttcgtgc cgcgatgtcg cggaggtcct
    16921 tcagaacggc cccagccgcc gggccaccag gccgacgacc tcggccatgt ggtccacgag
    16981 gaagaagtgg ccgccccgga agaccttcgt ctcactcgtc ccggtggtgt gctcggccca
    17041 tgcctcggcc tcgtcgaggg agacccgggg gtccctgtct ccggtgagca cggtcaccgg
    17101 gcagtcgagg cgtcggccgg gctcgtgccg gtaccgttcg atggcggtgt agtcgctgcg
    17161 gatggccggc aggatcatcg ccagcacctc cgggtcgccg agcagcatct cgttggttcc
    17221 gctcaactcc cgcagctcgg atacgagttc ggcgtcgctc ccggtatgca cccgcccgcc
    17281 ggcaccacgg gacggcgccc gccgaccgga cgcgaacagc cgtaccggcg caggcagccc
    17341 ggcgtcctgc atgcgcagcg ccacctcgta cgcgaggacg gcgcccatgc tgtggccgaa
    17401 cagggcgagt ggcttgtcgt ccaggtgccg cagcgcggcg aagatctggt ccgcgaactc
    17461 ggggacgttg tcgatcctcg gttcgtggag ccgggtctgc cgccccgggt actggagggc
    17521 cagcacctcc accgatgggt gcagtgctct ggacaccggg aagaagaagc tggcggagcc
    17581 gcccgcgtac ggaaggcacg cgagccgcac gctgctcagc ggcgcggggt gcgagacact
    17641 cacccatttc tcgaactgcg ccgttgctcg atgcatggcg gacgagctcc tcgtggtcgg
    17701 tgagggaata ccggaagcct aggttcgtgc aggtggcacc gcgtatcccc agatctgata
    17761 gtccggggcc ctcgagcggt cccgacgccg gtacggatgg ttagtcttgc gccgttccca
    17821 ttccggcaca cgtacctgcg ccagccgccc tgcgacgagg ggtttcccgt gcccgagaca
    17881 tcaccgcaca agcagcccgc cggcgcggga cccgagacgg acgcggacgt gatcgtcgtc
    17941 ggcaacggcc cggtcggggc cactctcggg atcctgctgg cacagcgcgg ccgccggacc
    18001 gtcgtcctgg aacggcgcgg acgcccctac accctgccca gggcgacgag cttcgacggc
    18061 gagacggcac ggctgctcgc cggctgcggg acgggcccgg gcctcggccg gatcaccgag
    18121 cccgccaccg gttaccagtg gcattccgcc gacggtgagg tcctcctcga catcgccttt
    18181 cgcgcagaag gcccgtacgg gtggcccgac gccagcaccg tgcaccagcc cgccctcgag
    18241 gaactgctgg cctcgcgggc ggccgcgctg cccggatcga ccgtggtccg gggccgccgg
    18301 gtggtgggaa tcgaggagca ggacgaccgg gtcgtggtga cggccgagga cgaggacggc
    18361 gcggcccgga cgtacaccgc gaggtgggtg gtgggctgtg acggtgccaa cagcttcgtc
    18421 cgggaccatc tggaggtgcc ggtcaccgat ctcggcttct cctacgagtg gctgctgtgc
    18481 gatgtgcggc tgcacgagcc gggcgagttc gtccccacca acgtccagat ctgcgaccct
    18541 gccaggccta ccaccctggt cggcagcggt ccgggacatc ggcgctggga gttcatgcgg
    18601 ctgcccggcg agcgggccgc cgacctgaac cgggaggaaa ccgcctggcg gctgctcgcg
    18661 ccctacgggg tgacccccga cacggcgacg ctgctgcgca gcaccacgta catcttccag
    18721 tcccgctggg ccgagcggtg gcgggccggc cgggtactgc tggccgggga cgcggcccat
    18781 ctgatgccgc cgttcgccgg gcagggcatg tgctcgggca tccgcgacgt cgtcaacctg
    18841 gtgtggaagc tggacctggt ggcgggcggc ctcgccccgg agtcgctcct cgacacctac
    18901 acggaggaac gccgcgcgca ggtgcaccgg tcgatcctgt cctcggtcca actgggtcgg
    18961 gtgatctgcg tgacggaccc ctcggctgcg gccgagcgcg attccaccat cctggcgggc
    19021 cgccgcggcc gcggtccggc gctcccggac ctggcgtcgc ccctcacgga ggggctcctc
    19081 caccgcagag cggacgggtc gcccctgtcc ccggcgggcg aggtggtgcc gcagggccgg
    19141 gtacgcggcc tcagtggcac cggcctcttc gacgatgtgg tcggccgcgg cttcgtcctg
    19201 atgctggcag agggcgcgga cgccggcctc gacgcggagc ggtcggcgtt cctcgcggat
    19261 ctgggcacgc acgtggtgac gctgctcccc gaggacggga cgccgcagag catgtcggtg
    19321 gccgacgtcg gcggcgtcta ccgtgccttc ctggctcgcc acggggccga cgcggtactg
    19381 atccgtccgg actaccacgt gtacggggcg gcctcaggcc tgggggcggc ggccgcactg
    19441 gtggacgacc tgcgggcccg cctctccagc agcagtaagg agcctaccaa ctgccccacg
    19501 tgacaacggg gttcgaccca cgtgaaccgg cctgcgatcc ggcccgccgc gaacgccgct
    19561 gccgaccggc gggtagactg tgacctgggg gcaccgcatg atcgttcgtc ttcacacacc
    19621 gatgacggac ggcggccgca cccgtctcca ccatgcgtca ggggcgcgct ggctcgcctg
    19681 ccgtcccgtg tcaggaggac ctgtgcaacg tggcgaagtc tggtgggtgg ggttcgacga
    19741 gcggcggctg ttcgtcctgc tgtcggccga ggacgcgtcc gggatccagg cgatgcaggt
    19801 cgtcgagccg gcgggcgtcg acatcagcgg tctcgccgtc gaagtgcccg tcggcgccac
    19861 ggaagggctg cccttcgaag gcgtgctgcg gttcgcgttc acgcgtccgg gcttcatccc
    19921 ctgcacctgg ctgaccaccg tggcccggga cgacctcgtc gagcgggcag gcgtgctgtc
    19981 gtccgagaag ctcggtgaga tcgaggacgc cctccgcatc gccggacagc cacaggagtg
    20041 gaccgcgacg gcagccgcga aactcagcga catgaaggac gccctccgcc tcggtcgccc
    20101 ggagtaggcg gacgaaggac ggacgccgcc gatggtgggg gcgacccggt ccagatgatc
    20161 gacaccgccc gcctccaagg cgtcccacac cggcaagatc atgacccacg cccggcacat
    20221 cagaccctgt ctccctgatc acctacaggc cggggcgtct gcgggtggtc catggtggtg
    20281 ccgtcgggct gccgcccgaa ggcggcctcc agaacgtcgg ggaggtcctc ctcggggacc
    20341 atggcgcgca cgtccgccag aacctgggga aaggcgtcgt cgtcgatgac gcccatgtgc
    20401 tcctgacgga gtcggtggat gatctcgacg agctccggcc tcagccgcat ccaggcgcgc
    20461 gaggtgcgga tctcttcatc gacctgctgc atgaaccagc gcatgacctc gtacgggacg
    20521 tccacgtgct ctgcacgcgg gtcgaagcac accgtgggtt cccgtgccgg atcctcgtcg
    20581 gggacgatcg cggtcacgag cgcccgttgc cccgccacga gatccagttc cagataccag
    20641 gcgtcatcgg gcacggagta catcgcggtg atcgcgaagt cgccgtcagg gtgtcggaag
    20701 gccatggccg catgctgcca cgctggaccg ggaaggccgt cgccgcgtca tgcggcccga
    20761 cggccctctg tcgggtcgtc gcccgggcat ggagtgatcc ggggtcaagc ggtgctgagg
    20821 ggatgggcgg ccgtggccga gcgtgggggc cagacatggg gcgcgagtat gcccaggacg
    20881 taggcgcggg cgacgagcgc cggacgggtc gccgcgccca gcaggtggcg cagccggctg
    20941 aggtggtagt cgagcgtctg ccgcgaaagg tgcagcgagg ccgctatgtc gccgttgctg
    21001 ctgccctgcg ccagcagtga caggatgcgg atctgcgcgg cggtgagcgg cgggtgcgcc
    21061 tcatgggcga ggctctgatg ggtgatcacg gcccagacgt gccgggcccg gccggcggaa
    21121 tggccgatag tcgtcaggtg cagctccgcc cgtcgttgca ggccatgggt gtcgacgagc
    21181 acggcggtgg tctcgacgcg ccgggtgcgg cgggctatca ggctgttcca ccgacggtgc
    21241 agccgttcga ggtcgggtac cggttgcggg gcgagcagcg tgtgggcgcg gcggcccacg
    21301 aggtcggtca gtccgaggtg gaagagttcc gcggccgcga cactcgcctc gatcacccgc
    21361 ccgttcgccg acagcagggc gcacggcagg ccgctgtggt cacgcagggc actgaggttc
    21421 tcctcggcct cctggcgctg ctccgtggcc cgcaggtgat cggtgatgtc cacgtagata
    21481 ccggcgacgc acgtgcggga ctcctcccgt acggggaagc ggtggccgac cgctcggccc
    21541 gtcgtgccgt cttggcgcag atagcgcagc gtgtgccgca ccggcgtgcc ccgggtgagt
    21601 atctgctggt cgagggcccg gaaccggtcg gcctcggccg gggcgtcgaa gtcctcgatg
    21661 tatctgccga ccagctgctc cggcacggtg ccgtagaggt gcgcgtaggc gtggttcgcc
    21721 cacaggtagc gtccgtcgcg gtcccggatg aaggcggccg cgggagcgag gcacacgagg
    21781 tccgcgaagg ccgcgtagcc gcgggacacc gcgggccccc cttccaccgg cccgtggtcc
    21841 ggggcgtgct gtgagccgtc cggagcggcg gggccgccgg tgcactgctc tcctgcccgg
    21901 cggggtccgc cgggattcgc atcctccgtc tgccacggct cgtcgacttc cgtccagaac
    21961 acgggaaggt tcttgagcgg tgtcttcagg ctcgggtcac ccacagcggt ctccgttcgt
    22021 acacgactgg ctgacgcaca gtcacatgac ggatataccg gccggtacag cacaagctcg
    22081 attcccggcc gagttgccgg caccggccgg tggcgccggc gccttaccgg tcggcgcggg
    22141 tgcggggacc ggaaaccgac ggatcgccac cgcgactcag gcatttgcct gagtcgtgag
    22201 cgttctctgc ggcgatatga gcggttacag cctggtcccc tggagtgtgc gagggggacg
    22261 ggccggacgg cgtccccgcg cacgatcccc gggcccaccg cgccgacggc gccgaggcgg
    22321 gcctctgccg accaggtgaa tggagacgga tttctgtgag cacggtgctg ttggtgcatg
    22381 ccaagggtgg tccgccgctc ggccatgtcc tgtcgcggac ggctgccagg gcggacgtgc
    22441 acctgctggc gctgagcgct cttccccccg ccgtggccgg atccgccggg agactgtgcg
    22501 cctcggtcac gacgccggac gacaggggac ggcgcgacct ggtctccctg atcgtctcgc
    22561 atgcccggga ggtgggcgcg gacgccgtga ccaccttctc cgagtacgcg gtcgtggccg
    22621 tcgccgaggc ctgcgagacg ctcggcctgc cgggcgcggg cccggccgcc gcactcgcgc
    22681 gcgacaagcg gctgatgcgc ggcacctggc agcgcagcgg cctgccgcag cccgcgttcc
    22741 gtcccgtcgc cacggaggcg gatcttcagg acgcggtgga ctccttgtcc tgtccgctgc
    22801 tgctcaaggc ggcctggagc gccggatcca cggcccacca gatcatcggc tccgcggctg
    22861 aggcgtccgc cgcctgggcc cgctcgcggc aggtcatgga ggactccgcc cggctcgggt
    22921 acgcggagct gcacgtcgcc gaggcggacg ccgacttcgt ggtcgaggag atcgtcagcg
    22981 ggacggccgc ggactggttc gacgagcccg gctggggcga ctacctgagc gtcgaaggcg
    23041 tggtggcgga cggcgtcttc caccccgtct gcctcagcgg ccggatgccc accgtcgagc
    23101 ctttcaccga gcgcgccggc atcacccccg ccctgctctc cccggaggcc caggaccgtg
    23161 tcgtcgacct ggcgcgccgc gccgtcgacg ctctgggcct gcgcgactgc gggacgcaca
    23221 cggagatcaa gctcggctcc gacggcagca tgtggctcat cgagaccgcg gcccggttcg
    23281 gcggcgcgat gacggtgccg cagatcgagg aggtcttcgg actggacctg gtgggcatgc
    23341 tcgtcgatca gctcctggga cgccctgtcg cctggcccgc gcaggccctg accccggcgc
    23401 aggcccgggg cgcggcgggc tccctcgtcg tcctcgcggt cgacggccgc ggcgaggcct
    23461 ggcaggaccg ccggatctgg gacttccccg tggtcgcctc gcacgtgccg ctgagcccgg
    23521 acagcgaact gtcggtcgtg gcggagagtt ccctgcccga cggcggtgtc gtgccggtct
    23581 acgaccccgc ggcgggcgcc aacaccatgg cggccctgtg cctgctctcc gccgccgacc
    23641 cgcgcacggt actgaaggac ttcgagaccc tggtggacgc cctgccccgg gtgctgcccg
    23701 ccgcgcaggg cgaggaggtc cccgcatgag cacccacctg gccaccggca ccgccgagcc
    23761 cgccacggac cgcacggtcg tcggcgagaa cctgtccctt ccgctcttcc ggaccctgtc
    23821 gggggtcctg gccgggcacc cctacctcaa ggtcgtcgtc gaccgcgagg agaacgtctg
    23881 gcacctcctc gacaccgccg cgcacccctt ccacgtcgac tacgtcgcca cccgggtgct
    23941 gggaatggac ctggcggccc tcgacgcgcg actggacgcg ttcaacgcct ccgtctacac
    24001 cgaccccgag cgccggttcc tgctcggcgt gctctccctg cacaccgagc aggaggacgg
    24061 cagggaacgg ccgttcctcg tcctggagac gaccgaggcc gacaccatga acggcgacat
    24121 gctcacgtac ttctacgagt tcgtgcgcgc acgcctcgac agcgggctgc cgctgctcct
    24181 caagcccgcc aaccacggcc aggaggagca gctctcggcg atcggcgagc agcgcgtgcc
    24241 ccgcgttctc ggccacgagc tgttcggctc ccgggagcgc acaccgctga accccggcga
    24301 cgccaccggg cggctgcggt tcttccgcac ggccgaggag taccgggcgg cggaattcgg
    24361 cctcggctgg gcggacatcg tggcgatgcc ctgtctgccc gacgacgtgc cccgcgtcgc
    24421 cggcttcgtc aacacggccc cgatcacccc gctctcgcac accaacgtcc tcgcctccgg
    24481 atggggcatc cccaacgcga tcgtccggga tctggagcaa ctcgtcgacc aggaaggtct
    24541 cgacggtgcc tgggtgcgtt accgggtcga cgaggacgac atatccctgc aacgcctcga
    24601 ccacgaaccc gacctgcgcg caccggcctg gcaccagcag cgcatccggc tcgaaccgcc
    24661 gctgctcgag gacgcccccg tgctgtccct gcaccggctg cgcggctccg accgcgaccg
    24721 gtacggcacg aaggcggcca acctcggcga gctgcaccac gtcctcgaca gccgtacggt
    24781 ggacctgacc gcctactacg gccgtccccg cccccctcgc gaggacctct acggccacct
    24841 cgccgcccgc ctcggactca ccgacttcac cgctgaacaa ctccgcttcc gggcagccga
    24901 gttcgtcgcc gaggccgtcg gcgccccgga cggcgtcgcc ctccccttcg cgctccagca
    24961 acggttcctc gcctcctcgc ccgcgctcca gcagggcatc ggcaagctga agatggcgct
    25021 cgaactcgac gccgtcgacg tcctcgactc gctctgcctg caccttcagc acctgatccg
    25081 gcacaccccc gtccccgagg cggtcacccg gcagatcgag cacgccttcc ccgcctcggc
    25141 ggcctcgcgc ggacggctgg tggtgcgctc ctcctccaac gccgaggacc tgcccggctt
    25201 ctccgccgcg ggcgtctacg actccgtcac gaccgtccac ggcaccggcg aactcctcga
    25261 cgccgtacgc caggtgtggg cctcgctcgt gtcgccgcgc agcgtccgac tgcgccacca
    25321 ggtcggtatc tccctcgacg agacctacat gggtgtgatc atccaggagt acgtgcccgc
    25381 ctccctcggc ggcgtcctcg tgacctgcaa cccgacccgc cgcgaggact tccgcaacgt
    25441 ctacctcaac tgctccccgg gatcccccga gcaggtcgtc gacgggacgg tgctgccgca
    25501 gcagtacctg tacaacaccg tggagggcgg cggccgtacc gtcgcgctgg gttcgtgggg
    25561 cgagggactg tccgccgccg tccgcgcccg gctcggcgac ctgtccctga ccggacggct
    25621 cctccagtcg cacttcagcg ggaccgacgt ggacaagccc ctcgacatcg agtggctgat
    25681 gaccgagcag ggcgatttcc ggctggtcca gatccgcccc tacgcgctgt gagggcccgc
    25741 ctcggacggt cgcgccccgg cagcgaggcg gccaccggcc tgaccgacac cgcccgccgg
    25801 atcatccggc tcaactacgg cttccagctg ctgttcaacc tgctgtggtg gatgccggtg
    25861 ttctacgcgt accagaaggc ggcgggcctc tcggacgcac agatcttcgg catccagagc
    25921 atctactacg tggccttctg cctgctggag atcccgaccg ggctgatcgc cgaccggatc
    25981 ggcacccgca actgcctgcg ggccggcgcg gtggtgatga cggccgcgaa cctggccccg
    26041 gtggtcagcg cctcctacac ggggttcctc ctccatttcc tggccatcgc cgccgggcgc
    26101 tcgctcacct cgggcgcggc gagcgcctac ctgtacgacg gactgcgagc gcaacggtgc
    26161 gacgagcact acctgcgggc ggaaggcacc gcgcgggcgc tggggctggc ggcgaaggtc
    26221 gtgtgctggc cgctggtcgg gccgctgatg acgctcgcgc acccggcacc gtacgtgctg
    26281 agcgccgcga gcgccgcggg ctccctcgtc tgcgcggtcc tgctgccccg gctcgccggg
    26341 acggaagccg ccgcggaccc gggccggagc agcggcggac gccggggaag cgccttcctg
    26401 cgggacgcgg ggaccgcgct gcgctgcgtc gcctcgtcac cctggctggc cctggtgatg
    26461 gtgcagggcg tggcggtctt cacgctgtcg cgcatctgcc aggtgaacct cttccagccg
    26521 atcctgctgg accacggcat cggcgagtcc tcgcacggcg gggtgctggc cgcgatgacc
    26581 gtggcggagg cggtggcgtc cgcgcggccg caatggctca gccgccgact gccaccggtc
    26641 gcctgggtgt ccgtcctcag cctcgccctc gcgggcaccc tggcggcgat gaccctcggc
    26701 gggccctggg tcgtcgtcgt actgctctgc ctgttcgccg ccgccaccgg cttcgcgttc
    26761 cccgtccagc gcaaactcgt caacgacgcg gttcccgcac acgcgccgcg cgccaccctg
    26821 ctgtcggtgg agagcatcgt ggaccgcgcg gtgtgcgccc tcgccgcgat cgccgcgggc
    26881 gcctacctgt cggccgggca cctcgacgcc ctgctgtggc acagcgcgct ggccacggcg
    26941 ctgctgctgg gggtcttcca gctgctgctg cgcagcgggg cggtcgcccg cgacggctgg
    27001 gacggggagg cggcgccacc gcggccccgg ccggacgccg gcgcggaggc ggacgacacc
    27061 tcgccggcgg cggccggcga gggtgctccc gaccgggcgg aggcggcgga cgccggcttc
    27121 acggaggttc tcgaacccga ccgggcccgg cgggcaccac gaacgccctg acccacggcg
    27181 acgggcgggc cggcggccac ggcaaccgtc agccggggcg gcggccgagg agttcgacca
    27241 gccccgccgg caggaacgca ggccggtgcg gcaggccgac ctggtaggag acgaagccca
    27301 cggaggaggc cacggacacc tcctgggccg tctccgcctc gtagacgacc cggcagccgc
    27361 ccgagccctc cttggcgcgc tgccacagga ccggggacgg tttgcgttcg gcctcggtgc
    27421 gcggcgtacg gatccggtcg ccgaagtccg cccacgcgaa cgcggtcggg ccccgccacg
    27481 tcgcgtcgac ctccgttcgc agccgtgccg cgcgttcggc gtccgtcgtg ccccaggagg
    27541 gcgggacatt ggtgatcagg ccgaccctga tgtggcgttc ccgcagggtc cgcagatacg
    27601 aggcagcccc tggcaggtag gccgtgctgc cgtcgtcggc cgtgtgcacc agggtctcgc
    27661 ccaggtcgaa gtacacgacg ggacacgacc gttcgccggg tgcgggtgcg ggtgcgggtg
    27721 cgggtgcggg tgcgagtgcg gccgcgcccc ggaccgtgcc gccctcctcc ggcgcggccg
    27781 tggtcgccgg cgcgcacagc agcgtcgacg ccagggccgc acccagtgcg agacccgcac
    27841 gggccgaagc gttggaagcg aatccgttca cgtgcaccgt cccgtcgccg cctgtcatag
    27901 ccatgacacg ctaacgctcc tgtggcgcgt ccgtgggcct ggcccactac tggcttgatt
    27961 ccgcccccct tcgggggcgc ccctgacggg cgggccgcca gacgggagtg cggtccttgt
    28021 cgaccagggc cgcacggacg ccctccagga agtccggggt ccggatgagc gtgcgggtga
    28081 gggcgagttc ggcatcgagg cactcgcgca gcgtgcgctg cctgccccgg gcgagcaggt
    28141 catgggtgac gtccaggctg tgcggtgagg ccgactccaa ggcggccagc gcgctgctcg
    28201 cccacgcggt gccgaggtgt cccagccggt cctcgatctc cccgagggtc ggcgcgccga
    28261 acgcccggtc gacgtcacct cgcaccgcgg ccagcctgct ccgcgccacc ggggaacggc
    28321 cggcgaggcg gctcaggacc acgtccaccg gctcgtcggg gtggtcggcc aaggcgtcgc
    28381 cgaccgcttc gagctcgtgc gaggggacga aatgcgtgcc gagccctgtg tacagggcgt
    28441 cggccgcgtc gagccggtgc cccgtgagtc ccaggtacat cccgatggct ccgggcagcc
    28501 tcgggaggaa atagctggcc ccgacatcgg ggaagaaacc gatcgctgtc tcgggcatcg
    28561 ccagtaccgc gcgttcggtg acgacgcgga agccgccgtg gacggacaga cccagaccgc
    28621 cacccatgca caggccgtcg atgagcgaca cgaccggcac gccgtactcg gcgatccggg
    28681 cgttgagccg gtactcggag gcgaagaacc gctcgctggc cccggcgtcc cccgcgaggc
    28741 tgtgctcgcg gatcgtacgg atgtctccac cggcgcagaa cgccttcggg ccggtactgg
    28801 cgagcaccac gcgggacagc cgtgcgtgct cccactcggc gagcacacgg tcgatggcga
    28861 ggaccatgtc cgtggtcagg gcattgagcg cctcggggcg gttcaggagg atgcggccga
    28921 cgccccggtg gacgtcggcg aggatctcac cagcagcgtt gtcagtcatc ggtcgccagt
    28981 atcggtcatc cggtcctacg gctcgtacca gccggacggc gacaccacaa cccggcacct
    29041 gacggagggc ggccgcccgg gtgcgcccgt acgctcccga attgtcagcg tccctaaggg
    29101 aacaaggaga cttcacgtgc gaactcgtat gctgggccgc cttctcggag gtctgctcgc
    29161 ggccggtctg gtcatgggca cggcgggtgc ggggcatgca gcaccgacgg cttccggtac
    29221 gacggcggcc gccccggccc gtacgtccgc gacggcggcc aaggccgcgg cctaccccaa
    29281 ggtgtacctc aacacggtgg tcaaccagtg gacgcactgg acccccgact actacgactc
    29341 cactcacgcg gggtggctgt acgcggggtc gaactacttc tactgcctca aggaaggcgt
    29401 ctactacacc gacaacggtc gccggagccg ctactggctc ctcacggacg acgacagcgg
    29461 caaccgcaac gtctacgtca gcgaggtgta cctcgaccag tggggctggg acaacgtcta
    29521 cagcctcctc gactactgct gacgtgctcc tgatgcccgg ccgcatcagc cggcgagcag
    29581 ggcacgcagc cactgctcct cgcgctcctc gatgtactcg gcgtcgttgc gccaggcggt
    29641 gccgtggccc tcggcccaca gtgtcgccca gggctggacg ccccgggcgg cccggtcgcg
    29701 caggaagtcg tgcatggagc gcgttcggcg ccccagcagg gggaccgtgt gacggcgttc
    29761 ggcctcgtcc aggccgtagg cgtcggcgaa gacccgcagc cgggccgcgg cgtcggggcg
    29821 ctgccagtcg ggatgcgcgg acagcggaat gaacccgtgc atggcgtacg cgacgtccca
    29881 caggcgggag ccggggccgg cggtgtccca gtcgatgaag gcccaccgcc cctcgtcacc
    29941 ggccacgagg ttccacggcg caagatcctg atgggcgatg atgtcgctgc cctcggcggg
    30001 gatcagcacc tgccagtgcg cgtcgggcgg tggtgtgaag ccccgcacgg cctcgtggaa
    30061 gtcccggatc agtcgcgcca cgtcggccag gtgcccctcg gcgtccagca gggagaaccg
    30121 gtcgggccag accacgtgtc ccggcatgaa ggtcaggacc tcccgcccct ggtcgtcgat
    30181 gcccagcggg cggggcgccg cccggtaccc cacctcgtac aggtgggtca gcagggcgtg
    30241 cacagcgggg gtccacggtc cgctcgggcg gcggacggtg tctccgaccc ggacgacacc
    30301 ggcgctgacg ttcccgcccg gcaacggctg ttcctcatca cgccgttcct catcacgctg
    30361 caccgggcca gcattcccga tcggcccgca gcgctcaccc catttacggt ggtcaccccg
    30421 ggcgacggat ctccgctcgt gccgagcccg cccggaagcc gtcggccgcc ctcccggagg
    30481 agcatgtggc gccgatgacg tggtcgacga catcgtggag gctggagcgg tgacggtagg
    30541 cggcacgctg ccggtcggct ccgctgccct gggtgcgcag gcgccgccac tggctgcgta
    30601 cgaggtcgag gtcaccgctg tggcgcaggg caggggacaa ggcacgcagc atgcgctcga
    30661 cctgcgccgc cgcagggacc agccggcggg tgatggggtc gagggcctgt ccggcaagtc
    30721 cgtcgcgtgc tgcccgccag gaggccgcac gcaggatctc ggggccgggg cggggagccg
    30781 gctcaccggc gcggatcgcc tcgagggcgg tggcgaccaa ggcgcgcacg acggccgcga
    30841 gcaggaccgt gtcctcggga gtgagtgccg cgtcggcgac gcgtacctcg acggtgggca
    30901 gatgatggga gggacggacg tcccagtaca ggccgccccg gtccagaacg gtccgcgtga
    30961 ggatgagttc gtcgacgaga tcctcgaagt gggcggggga gtcgaagtag ggcggcggtc
    31021 cggcgaccgg ccatcgcccc caggcgatgg tgcgccagct cgcgtagccg gtgtcacggc
    31081 cttcccagta cggggagttc gccgccagcg cggtcaacgt cgccagccag ggccgcagat
    31141 ggttgctcac ttcgatcgct tcgcgggggt cggcgacgcc gatgtgcacg tggcacgcgc
    31201 aggcgctctg ctcgtcgtcc agcgcccgga agagggacat gctctccgcg taccgcgggc
    31261 ccggcgtgag ggggacgggt gcgacagggc cggtgatcgg tgatccgctg gaggcgatgc
    31321 gcagaccccg ctcggcggcg gcgcgcgcca accccgcccg tacggtgcgg agttccgcga
    31381 ctgcctcgtt caggcaggtg tggggttcgg tgcggccttc gacctgatag cgggtcagtt
    31441 cggtaccgac gcggtgcccg agttcgtcgg cggccgagtc ggccacctgc gggccttcgg
    31501 gcctgagcgt gcggctgacg gggtcgacga ggaggaactc ctcctcgatc cccaccgaca
    31561 gcgcggcggg cacctcccgg aacgaggagg ggcagccggc cggggcatcg tccggcggta
    31621 actgctgctg cggctgactg gtcacaatgt tcgactgtgg cagagagttc cgccacggag
    31681 gccgcgaaac ggcatgctcg tccgattctg aacccggcag ccggtgcatg agccgtgaac
    31741 tcggcggacc ccaccgggga agagagagtg tgaccacatc cgatcagaga cggagacccc
    31801 gtgaccggcc caccggacgt cgggcacgac gaccacgaac accaccacga cgactcgtcc
    31861 gccatcgccc agtctctgcg gcggcccgag gtcttcgcgg tgttgtacga ccggtacgcg
    31921 gccgacgtcc acagatacgt catgcggcgg ctcggcgacg cggccgccga cgacctcacg
    31981 gccgacactt tcctcgtggc gttccgagcc cgttcgcgct acgacctgac ccgcacgaac
    32041 gcccggccct ggttcttcgg catcgccgcc attctgatca gcaagcagcg ccgcaccgag
    32101 gagcgcgccc tgagggcgct cgcccgcacc ggccacgacc cggtcaccga gtcgtgggtc
    32161 gatcacgcgg acgaccggat caccgcgcag gccgtccacc gcctcctcgc cggcgcgctc
    32221 gcctcgctgt ccggcggcga ccggcacgta ctgctcctcg tcgcttgggc cgacctcagc
    32281 tatcaggagg tcgccgaggc gctcgccatc ccggtcggca ccgtccgttc ccgactcaac
    32341 cgggcgcgca ggaaggtgcg ctccgcgctg ggtgacgacc ccactctcgt gcaggatttc
    32401 gccccggagg ccggacatgg atgagatgac gacgctgaag aacttccggc cggacgcgcc
    32461 cgcctgcgac cgggcccggc tggtgcccgg gcggcagagg ctcctggacg ccgccgccgc
    32521 acagaggcgg cgccggcgct tctggccacg ggccggctgg aagctcgccg ctgcgggcgc
    32581 tgccgccggg gtggccgtgg cggcggtgct ggtggcgcag gtgatgccga cgaaccacac
    32641 ccaccgggtg gaggccgagt acgcaacgtc tcccgaaccc gccgacgggc agtggctcta
    32701 ccagaagacc ctgacccggc agtcgacgct caacttccgc gacgacctca atcccgttcc
    32761 ggagaagggc gccccggcat acgcggagtt cacgcaggag acctggacgc agtacggcag
    32821 cggcaagacc cgccgcatgc tgatgcaggg tggcctggat tccgtagtgg gcaaggcggt
    32881 ggccggatcg ccgaaggagc tgcgccggaa agtgcagaaa ctgccgagcg agccgcaact
    32941 gctgctgcgg tctctctcca agatcatccg ccacgggggc gattacgagc ggatcgcgta
    33001 cacgttctcc agcgcggaca ccattccctt cgaagtccgc atctcgctgt tccgtgcgct
    33061 cgaaacgatc cccggcgtgg tggtccgtcc gcagctcgtc aaggacgcgc tgggcaggcc
    33121 tgcgctggcc gtccacccca cggacgacaa ctcgttcacc aggcagaccc accgccggga
    33181 ggagctgctc ctcgatccga agacctacga gtaccggggt gaacgcacga tgatgctcgc
    33241 cggcggagtg atcgactcca aggtcacgac agaggaaacc ctgatcagcg tctcagccgt
    33301 gcagaggttc gcggctgccg tggacgagcc gggcgtgcgt ccctgagctt tcgtcctggc
    33361 ggtgcgcctt gccgggtgcc gacgcggccg ggtgggcgga gtgggatcag tcggtgtcga
    33421 ggccgtcgat caggcggttg aggaaccggg tgaaggtggc ttcgggcgtg agggggcgtc
    33481 cgggggcggc gagggcttcg gcgagttccg ggtgacggcc gtccgcggcg acagccgcga
    33541 ggtagcgggc ttcggctgcg gctcggtcgg gggactgcga ggccgccgtc cgcgcgatct
    33601 catgggcgac gtgcccggcc acgaacgcgg tgagctgggc gaagacctcc agcttcgccg
    33661 caccgtccag cccggagggc cgcagggcgg ccagcgcgcg ttccaggaag gccagcgtgt
    33721 tggggccggg gatgcgacgg gcggccagag cggcgggcag ccaggggtgt cgcagcatat
    33781 gggcgcgctg gaggcgggcg atggccttca ggtcggtgcg ccagtcgccg gtgggggtgc
    33841 cggtggtcgg cagttcgccg ctgacgtggt cgaccatcag ctccagcagc gtctccttgt
    33901 cgggggcgta gctgtagagc gacatggcgc cggctcctac ctgtgcggcg accttccgca
    33961 tggtgaccgc ttcgagcccc tccgcgtccg ccagcgcgac ggctgccgcc gtgatcgcct
    34021 ctcggctgta ggcgggcttg cggcccctgc ggggccgggc cgggctcagc cagagctgct
    34081 ccgggctgat gcctggggcg tcggcccctt cgtcacgggg catggtccac gctcctccct
    34141 tgatcgaggt ggcccttgcg cgcctcatcc aagcatcctc tattctcgta caccgtacgg
    34201 atatggagga gagggacgat ggcatcacgc acgcacggtc ctgtgccgag gccgacctgg
    34261 gcaccgcctt ccggtaggcc gccactggcc tcacggatca tgagggcgac gtggcgcggc
    34321 ctgccggccg ggcgacacga tgtcgggtgg gagccgggtc tgccggtgcc ggccgccgac
    34381 ggcagccaac tgatcacgga ccactacttc ccgcgcgccg agggcgactt ccccaccctc
    34441 ctggtgcgct cgccgtacgg caggggtctg ccgtggtctc ccatgtacgg cgtcctcttc
    34501 gccgaacagg gctttcacgt ggtgcttcag agctgtcgcg gcaccggtgg ctccggaggc
    34561 gagttcgatc tgtggcgcaa cgaggtcgcc gacggccggg ccaccgtgtc ctggctgcgc
    34621 gagcagaact ggttcgacgg aaggctgggg accgtcggcc ccagttacct gggctacgtg
    34681 cagtgggccc tcgccgtgga cccgccgccg gagctgaagg cgatggtggt gcaggtgggg
    34741 ctgcacgatc ctcacgccct gttccacgca cagggcgcgc ttcgtctgga gaacgccctc
    34801 gccgtcggtg tcggcatgac gtatcagcac caggggatgc gagcgttcct tacggcgacc
    34861 cttcgtctgc accggcgcct gcgtgatgtc gtcaccgcgc agccgctgcg cggggcgtac
    34921 gtgaccgccc tcggcggcga tgtgccctgg ctggacgacg tgatgtccca cccggaggcc
    34981 gaggacgcgt actggcaggg tgcgtcgctg gcgacggtgg cggagcggct ggatgtgccg
    35041 accggcttga tcaccggatg gcacgacgcg ctgggcgacc agacgttcga gcagtaccgg
    35101 cgactgcgtg aggccggttg ccggaccgcc ttgctcgtcg gcccctggac ccacacgtcc
    35161 gcgctgcaac aggggtggcc cgaggtgttc gccgagagcc tcgcctggct gcgcgcgcac
    35221 ctgtacggcg atcgctccgg cctccgtccc accagggtcc gcgtgcacgt cggcggcgaa
    35281 gacgactggc gggacagcga cgactggccg ccggccgcgg ccgtgaaccc gtggtttccc
    35341 accgcgcagg ggcacctcac ccggcaggct cccacggact ccgcaccact gacgtcgttc
    35401 cgctacgacc cgggtgaccc caccccctcc ctcggcggcc cgctgctctc ccgtacggcc
    35461 gggcctcgcg acaaccgaac tctggagacg cgggacgacg tactgacgtt caccggcccc
    35521 ccgctgaccg agcccgtgga catcctcggc ccggtctccg cgcgcttgag catctccacc
    35581 gacaccggcc acgccgacgt cttcacccgc ctgtgcgacg tggacgcaca aggccgctcc
    35641 gtcaacatct gcgacgggct gggccggctt cggaccgccg gacaggcgcc ctcgcacatc
    35701 accgtgccga tgagttccac cgcccaccgc ttcgccgtcg gtcaccgcat acgctggcag
    35761 atcagcggcg gcgcccatcc tcgctacacc cgcaatcccg gcacgggtga gtcgccgatg
    35821 gacgccacca ccttcacacc ggtgcgcatc acgctccatg cggactcggc gctgatgctc
    35881 gcgacaccac gggcggcgcg ctctccccgc gattgacgag cacaacgggc tcgggcgccg
    35941 agaatgccgt ggtgcgaccc ggcgccgtca ccgggccggt gcggggcccg gaggtggggg
    36001 tggggttcgg gcggggcggg tggctcccgg gtcgcgggcg gccaggagtg ccacgccgat
    36061 ttccgacagg gcccgggggt cggagaggga gcggcccgtg agttcctcga tgcggcggag
    36121 gcggtagcgg accgtgttcg ggtggacgaa gagggtccgg gcggcctcgg tggccgagcc
    36181 ggcggcggcg aaccagtgtt ccagggtgtc cagcaggcgg gcgcgttcgg cgaccgggag
    36241 gtcgatcagg ggctggagca ccacgcccac cagatgcgcg gcctcggcgg gggcggcggc
    36301 aacgaccatg gccagcgggt cgtcgtcgaa ccgggcgacc ccggcgcgcg cctcgcgcag
    36361 gccggcgagt gccaggcggg cgaagcgcag ggcctgcggg gtgtcgcgca gggaggggaa
    36421 ggacgggctg acacccaccc gggactgtgt accgcgcagg acgcgcagga aggtgctctc
    36481 cgcctccgcc gtcggcagcg cgaccaggcc gatgcgatgg tcgggcagca gccgccaggc
    36541 cgagggcagg cgggcccggc gcagtgcggc ctcgactccc gcgagcggtt cctggcccgg
    36601 tacggcggcc gtggccgcgg cgaccgcgta gggaccgtgc tcgggcagac ccagctcccg
    36661 ggccgcctcc cacagcgtgc tgcggtcggc catgacgccg gtgaacaacg cctccaccag
    36721 ggcggaacgc cgggcacggc cctgtgaggt cagctcggcg gaggtctcac ggtaggccgc
    36781 cgccaccgct tccgcgtaca gcccgaacag cgaccagatc tccgccgact gggacaccag
    36841 ctgatcgtcc gtgacgccgg ggtgggtgcg tgactccagc aggatctccg tccacagctg
    36901 ctcgaagccg acccggtagg cgtgcagggt gtcggcgagc ggcaccccct gttcggcgcg
    36961 cacccgcccc gtctcgcggg ccgggctggc gtcaggggcg tccgcgcgct cgaggtggct
    37021 cagcacgagg tccgcgttgg ccgtgcacga gctgcgcagg gagtcgaagg ggatcagtga
    37081 ttcctcgtcg tacgcctcga cgtccgagcg gatgcgccgc gcgatccgct cacccagttc
    37141 cggcagcctg gcatgcagcg ccgcggccac gcctgagatg tccatcaccg cagcttaacg
    37201 gcaccgtttt gttcctgcgg acaatcccgc gggggcggcg ctgtcctggc gcccataggc
    37261 caccgtcagg agcggcagca ccatgtcgtc gagatgaaca gcggatttcg acggtgatgt
    37321 tcgtggaggc ggtcatggcc aatcttgcgc agtacctggt ggagacggca cagcggcagc
    37381 cgggacgtcc cgcgctgcgc ctgggcgagc acgtcaccac gtacgccgag ctcgacgagc
    37441 gcagtgcccg cgccgccgcg ctgctgcggg ctcagggcgt gcgccccggg gaccgtgtcg
    37501 ccctgatgct gcccaacgtt cccgagttcg tcgtcctgta ctacggggtg ctgcgcgccg
    37561 gcgggatcgt cgtcccgatg aacccgctgc tgaagacgcg cgagaccgcc tatcacctgg
    37621 aggactccgg ggcggtgctg ctgtgcgagt ggcatctggc gccgggcgag ggcgcacagg
    37681 gcgcggaagc cgccggggtg cggcacctgg ccgtcgaacc cgccgccttc gcggcgctgc
    37741 tcgccgggca cgagcccgtg cgcgaggtgg cggacggcgt cgacgacgtg gccgtgctgc
    37801 tgtacacctc cggcaccacc gggcgtccca agggcgccac cctcacgcac tcggggctgc
    37861 ggcacaacac cgaggtcaac gcggtccacg tgcagcgcat cacgccggac gacgtggtgg
    37921 tgggctgtct gccgctgttc cacatcttcg gccagatctg caccatgagc gtggccgtcc
    37981 gcgccggcgc ctcgctcacc ctcgtgcccc gcttcgaacc gcaggccgtc ctggaggcca
    38041 tcgcgcgcga ccgcgccacg gtcttcgagg gggtgcccac gatgtacgcg gccctgctcc
    38101 agcacccctc gcaggcggac gtctcgacgc tgaggatgtg catctccggc ggcgcctcgc
    38161 tgcccgtcga ggtgctgcac ggcttcgagc ggcgcttcgg gtgcgcggtg ctggagggct
    38221 tcggcatgtc cgagaccagc ccggtggtca cgttcaacca tccggaccgt ccgcgcaagg
    38281 ccggttccgt cggcacgccg atccgtgacg tggaggtgcg gctcctggac gccgagggcc
    38341 gggacgtggc gcccggcgag gtcggcgagc tcgcggtgcg cggtccgaac gtgatgaggg
    38401 ggtactggaa ccgccccgag gagacggcgg ccaccgtcca ggacggctgg ctgcgcagcg
    38461 gtgacctcgc ccgccgggac gaggacggct acctgtacat cgtcgaccgc aagaaggaca
    38521 tgatcatccg gggtggctac aacgtctacc cgcgcgagct ggaggaggtc ctgcacgagc
    38581 atccggccgt ggccctggcg gccgtggtgg gcctgccgca cacccacctg ggtgaggaga
    38641 tcgcggccgc ggtcgtcctg cgcccgggtg cccgtgccac ccccgacgag ctgcgggagt
    38701 tcgtcaagag ccgggtggcc gcgtacaagt acccgcgcga ggtgtggctc gtggacgccc
    38761 tgccgaccgg cccgagcggc aagatcctca agcgggagat cactgctccg gccggctgac
    38821 cccgggggcc ctgtcccggg cccggccggg ggcgtgcggc gccaggccgg gcgccgggcg
    38881 aaaaccggcg gtgacggggc cgcgccggat ggcagggtgg gcggtcgtat ccgcccgacg
    38941 cgacaggagc ccccggcatg gccgtcatcc accgcaccgt cctcgagccg accaaactgg
    39001 aactcctggc cgcctggctg cccacccggc cctggtacgt gccgggcgcg ggcgggccgg
    39061 aactgaccaa ggccggcggc ttccggctcg acgacccgca gggcgaggtc ggcatcgagt
    39121 tcatggcggt caccgacacc gccggcgatg acgcggtcac ctacctcgtg ccgctcacct
    39181 atcgcggagc gcccctggcc ggggcggagc acgcgctcgt cggcaccatg gaacacgggg
    39241 tgctcgggcg tcgctgggcc tacgacggct gccacgaccc ggtgctgcgc acccagctgc
    39301 tcgccctgct ccggggacgg gtcctggccc aggaccagaa caccagcgac acccccgacc
    39361 gggaggtcac ccgctcgtac gacggtgacg gcggcgacct ggccgacctc gcggccggtg
    39421 cggtcgacga ccgcgagggg acccgcctgt ccgccgggcg gggttccacc ctgttcctgc
    39481 atcgcgtcct gcgtccggcc ccggacggcc cgccgtccct gccgccgggg acgaacggcc
    39541 acgtcgcggg ctcctggcgg acgccggacg gatcccgcgc gcgagggctg ttcgtcgtcc
    39601 tgcggagcgg cccgggggac cggtacgggc ggaccggccg cccggcctga agggtgcggg
    39661 gaccggtggg tccgagaacc tccgcccggc accgttggac gacgcggatc ggggtaccag
    39721 gtcccgcatg gcacagaaaa aagatcacgt cgaatcggtg cgtgccgtgc ggcagttgcg
    39781 gcgcgtccgc cctctgtacg cgggaggcgc tctcctgtgg gccgcgtcgg cggcctggac
    39841 cgggtgggac gaacccggaa gccggcagat gtgggtgtcg gtgctgttcc tcgtcgtctt
    39901 caccggactg ctctccgtca cgtcggtgtg gctgtcgcgt cagcgggccg ccggcgcggg
    39961 ccggtccgtg caccacgccg cgccgcggcg cgccttcgcg aaccgccatg ccagtgcctg
    40021 acccctgaac tccgcagagg acgcaccgcc cgccccgccc acgaagaccg ggcccgccgc
    40081 gcacgcggcg ggcccggtcg ttgcgtgcca ccccgcggcg gtcgtgccgt tgccccacgg
    40141 ggcgttcggt ggtcccatga ggtcgcggtg ccgtcgtgtg tgcggcgggc cgaacgggac
    40201 atgacgtcca cacgtgtgcg accggaccga cgaggagtgc gcatggcagg gcagttcgaa
    40261 gcgacggtgg aggtcgatcg ggctgtcgag gaggtgttcg cctacctcgc cgacggacgc
    40321 aacgacccgc agttcagccc ccgggtgctg cggatcgacc ggacccccga cacaccgacc
    40381 gccgtgggca ccgtcttccg cagcacggtg aaggacgccg ggatgaagac ggccagggag
    40441 ttccgcatca ccgcgttcga ggcaccggtg aggatccgct ggcaggaggc ctccaagaac
    40501 tccgtgacgg tacgcgaggg cggctacgac ctggagcggc tgaccgacgg caggaccagg
    40561 gtccgcatct tcaactccct ggaggggcac ggcgtgggca agctgctcgt cggcctggcg
    40621 ctggccgcgg cccgcaagga cgccgacgcc ttcggcgccc gcatcaaggc ggcggccgaa
    40681 gccgcgatcc ccgcccgctg acgtccgccg agcggggccg cggcggaggc ggagcgacgg
    40741 ctcagcgggc gatgcggtgc ctgcggccgc cgcggcggaa gcggagcccc acgtaacaga
    40801 ggtcggcgac gagcaccacg gcgccgatga tcagcaggta gaacagcccg tggaccgcga
    40861 atccgatgat gcccaggacc agcgccagca ggatcaggaa caggaacaga ctcatgggcc
    40921 ctcccgcggc ctcgggggtc agcgacgggc gaggcgccgc tcgccgccgg cccccggcgc
    40981 gtagtccagt gcgtagtggg cgaagacctt cggctcgtcg ggggcgagca gctcgccgtc
    41041 cgtgtcgatc gacggcgcct tcttcacggc gttcttgtcg tgcgcgacct tgaggtaccc
    41101 cgggccgacg gtcgccccga ggagcggcac gaacaccagg cggcgcctgg tgggcagccc
    41161 cacggtcacc gtggcgaagg acggcaggtc ggtcccggtg tccacgtaga ccgactccag
    41221 gacaccgatc ctgtgcccct gcgcgtcgac cacgtcgtga ccgcgccact cccggatatc
    41281 gcttgcctcg accatcgttc gacctccgca gatccgtgta cccgggttct tgtcaccgat
    41341 gtcatgtacg tgagtcacag gggccgggcc atgagcaccg ccacgtcgtc ctgagccgga
    41401 tggggcagca tctcgccgag cacgccgtcg cagagcgcgg ccagcggctg cccggggaag
    41461 cgcagcgccc gggcgagccg gtcgagcccc tggtcgaggt ctgcggcccg cgtctcgatg
    41521 agcccgtcgg tgtacaggac gagcacactt cccgggggga gggggatccg ctcggtgcgg
    41581 aactgccggc cgcccgtgcc cagcggggtg cccggtgagc cgtcgaggaa ggcggggggt
    41641 ccgccgggcg gcaccacggc cggcggcggg tgaccggccc gcgccacgag acatccgccg
    41701 gacgccgggt cgtggacggc gtagacgcag gtcgccatct ggtcctcgcc catgtcggcc
    41761 accacggtgt ccagcgagcg cagcagacgg gccgggtcga cgtcgtgccg ggccagggcg
    41821 cgcaccgccg tgcggagctg gcccatgagc gccgccgcgt gcacaccgtg ccccatcacg
    41881 tcgccgatga cgagtccggt gcggccctcg ggcagcgcga tgacgtcgaa ccagtcaccg
    41941 ccgacgtcgt gctcactggc gggcaggtac cgtcccgtga gttcgaggcc cgggacggcg
    42001 ggcagcgcgc tgttggtcag gctgcgttgc agggtcagcg ccgccgcgcg ctgccgggtg
    42061 tacatgagcg cgttgtcgat gttcagggcc gcgcgcgccg ccagttcgtc gatgagcaca
    42121 ctgtcctgct cgtcgaaggg ctcccggctg cgcagccggg tcaccacgac cgccccgagc
    42181 accttgcccc gcgccaccag cgggatcagc cgcgcggagc ccagacccat caggtaggcg
    42241 cgcagttcgt cggcgcgggg gtcggtgacc agcgccggga cgtcggaccg gtagaggtcg
    42301 gtgggacggc cgtccgcgat gacccgttca tagagggagc cgcgcgcgat gcgggacgtc
    42361 atgcccggca gcagccgcgc cgtcggcgcc gacgggtcgg ggaagagggc ggccatgcgc
    42421 cggacgacgc cgtgggtggc ggcggtggac tcgtccggtg cgagcacctc ttcgaggagc
    42481 tgtacgtcgg cggagtcggc gagctggggg accagcatcc gcacgatctc ctccgaggtc
    42541 tgccgcaggt ccaaggtggt gccgatccgg gtgccggcct ccgccagcag ggcgaagcgg
    42601 cgccgggcgc gggcggcctc gtgctcggcc cgctggctct ccgtgatgtc gatgagcgag
    42661 gcgatcagcc ccagggtccg tccggcgccg tcgaccaggg gggcgtagga gcacgaccag
    42721 gtccgctcgc ggtcggggtc cgccggggtg cgcccggtgc ggcgcacgtc gacgacggcc
    42781 ttgcccccgt ccagcacctc ccgcatcgtc gactcgagcg cgacggcgtt gacgcccggc
    42841 acgacctcgg tcagccgtct gcccgtgtgc gcggccgcgg agacgccgtt catccgggcg
    42901 agcgcgtcgt tgacccgcag gaaccgcagg tcggtgccga gggtcgccag gccgatgggc
    42961 gactggctga acaggctctc cagcgccgcc agggagtcac gcatgcgcag cacctgcgag
    43021 gtctccacgg cgatcagcag agcgccggtg cgcccccgag cgtcggcggc cggcacgatc
    43081 cacatctcca tcgtgacctc gtgcccgtcc cggtgccgca ccgcgagggt gccgaccacg
    43141 gtctcgccgc cctggacacg gtaggtgagc tggtcggcga gctcatgccg tccctcgggc
    43201 accagcaggg ccgccgcggc acggccgagg acgtcctgcg gccggtgtcc gagcaggtcc
    43261 tgggcggcca gcgaccattc cacgatgcgc ccgtccgagt cctcccgcca cagggcgatc
    43321 ggcagcagct cgcgcagcac acccgcgtac ccgacagcac ccaaaggctg ctccggcgtc
    43381 ccgcccgccg tctggggggc atccaccgta cgacctcccc gtcaggcgat atggcgtatg
    43441 aaaagaccat atccggaagt tcgccaacca ccccttgtcg acgtccgcca ccggccgccc
    43501 ggtgacggtg tccggcgcgt ccggggtcag gccgtggccg ccttctcctt gcccgcggcc
    43561 ttcgccccgc ccgcggcctg cggagcgtcg gcgacggtgt agaagacgga cgtcccctgc
    43621 ttggaacggt gtgcctgggc cttggcgacg aggccctcca gcgtggtccg caccacggtc
    43681 gccttgacgc tgcgctccgg gtgcgcctga ccgagggccg tggtgatct
//
