LOCUS       NZ_BMSI01000010        24868 bp    DNA     linear   CON 02-AUG-2024
DEFINITION  Streptomyces asoensis strain JCM 4185 sequence10, whole genome
            shotgun sequence.
ACCESSION   NZ_BMSI01000010
VERSION     NZ_BMSI01000010.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces asoensis
  ORGANISM  Streptomyces asoensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 336449)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014649075.1-RS_2024_08_02
            Annotation Date                   :: 08/02/2024 04:45:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,813
            CDSs (total)                      :: 7,736
            Genes (coding)                    :: 7,563
            CDSs (with protein)               :: 7,563
            Genes (RNA)                       :: 77
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 53 of 173
            Pseudo Genes (incomplete)         :: 140 of 173
            Pseudo Genes (internal stop)      :: 10 of 173
            Pseudo Genes (multiple problems)  :: 28 of 173
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:21:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 311581
            Orig. end                         :: 336449
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMSI01000010.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24868
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX) and not alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..24868
                     /SMILES="C1=CC(=O)C(N)C=C1C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24868
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[20000:>24868](+)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..>24868
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     gene            complement(82..849)
                     /locus_tag="IE189_RS24585"
                     /old_locus_tag="GCM10010496_50050"
     CDS             complement(82..849)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015338.4"
                     /locus_tag="IE189_RS24585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_50050"
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="WP_189925004.1"
                     /transl_table=11
                     /translation="MRLLTMNALYTGDVPARLRALGAALDRSDLDIVCLQEVMYRRHAR
                     LLRRAAPAYRYVACSGTALLKGGLVLLSRWPISRYRFVRYPTTGPVRGELLMRKGAQLA
                     SVATPAGELVVVNTHLSANRDDDWSPTNRYTRIAAGELARLASLIAAVDPSLPVAVVGD
                     LNLPRESAALTDFITAAGLSDVLAGDTRPTYRPTPGWPSPPALDHILIRSAAGETLTGS
                     ADLVFQEEVTLPDGRQTHLSDHYGVQAQLTRSK"
     gene            complement(1053..1430)
                     /locus_tag="IE189_RS24590"
                     /old_locus_tag="GCM10010496_50060"
     CDS             complement(1053..1430)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020132057.1"
                     /locus_tag="IE189_RS24590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_50060"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_189925006.1"
                     /transl_table=11
                     /translation="MRIGELAARAGVSVRSLRYYEEQGLLTSARSTGGQRHYTEVHIER
                     VTFLQRMYTAGLSSRTIAELLPCVDSPSAENADAALLRMAEERERLSEHIAELLRTRDA
                     LDGLMATNRAFRERLNSPVSG"
     misc_feature    complement(1450..1465)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.52"
                     /tool="antismash"
     gene            1549..2622
                     /locus_tag="IE189_RS24595"
                     /old_locus_tag="GCM10010496_50070"
     CDS             1549..2622
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020132056.1"
                     /locus_tag="IE189_RS24595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_50070"
                     /product="alkene reductase"
                     /protein_id="WP_189925008.1"
                     /transl_table=11
                     /translation="MASLLSSYRLGDLALPNRVVMAPMSRVRAAAGGLATPSMARYYAQ
                     RATAGLIVSEGVQPSLLGQSNPGTPGLHTDDQVASWRPVTDAVHANGGRIFAQIMHGGR
                     VSHPDTTGMRPVGPSAVAAVGEVFTPTGPQPVPLPRALETAEVPEQIRSYAQAARRAVD
                     AGFDGVELHGANGYLISQFLSANANLRTDRYGGSVTNRIRFAVEAVAATVEAVGAARTG
                     IRLSPGGPFWGIEETDVAEHYTALLGELSRLDLAYVHLEATADEETLLGLRRVWPGTLV
                     MNPVLPLGPKQTGRAEADHWLGLGADLISFGRAFIANPDLVERLRTGLPIAPADESTYF
                     QGGDDGYLTYPAYQHAQ"
     gene            complement(2692..3453)
                     /locus_tag="IE189_RS24600"
                     /old_locus_tag="GCM10010496_50080"
     CDS             complement(2692..3453)
                     /NRPS_PKS="Domain: PKS_KR (7-164). E-value: 5.9e-09. Score:
                     28.0. Matches aSDomain:
                     nrpspksdomains_IE189_RS24600_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006130320.1"
                     /locus_tag="IE189_RS24600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_50080"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_189925010.1"
                     /transl_table=11
                     /translation="MALLQDRIVLVNGGSQGVGAGIVRAALGAGATVLFTGRRVELGEK
                     LAEDTGAHFMRADLADPAQARDSVVRTVSAHGRIDCLVNAAGLTSRGSLLDTTPELFDR
                     HMAINLRAPFFAMQAAVTDMKARRAPGTIVNIGSNCARGGPPHLAPYSAAKAGLAGLTR
                     NAAHAHRWDRIRINGLDIGWTDTEGEDATQRAFHGAGADWRARAAAAQPMGKLGQVDEI
                     AEFVVFLLSDRSGVVTGSVIDWDQNVFGGQD"
     aSDomain        complement(2962..3432)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS24600_PKS_KR.1"
                     /evalue="5.90E-09"
                     /label="IE189_RS24600_PKS_KR.1"
                     /locus_tag="IE189_RS24600"
                     /protein_end="164"
                     /protein_start="7"
                     /score="28.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="IVLVNGGSQGVGAGIVRAALGAGATVLFTGRRVELGEKLAEDTGA
                     HFMRADLADPAQARDSVVRTVSAHGRIDCLVNAAGLTSRGSLLDTTPELFDRHMAINLR
                     APFFAMQAAVTDMKARRAPGTIVNIGSNCARGGPPHLAPYSAAKAGLAGLTRN"
     gene            complement(3470..4648)
                     /locus_tag="IE189_RS24605"
                     /old_locus_tag="GCM10010496_50090"
     CDS             complement(3470..4648)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173405.1"
                     /locus_tag="IE189_RS24605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_50090"
                     /product="phytanoyl-CoA dioxygenase family protein"
                     /protein_id="WP_189925012.1"
                     /sec_met_domain="PhyH (E-value: 1.9e-34, bitscore: 113.9,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPTAVRSLTWLTEADCDLDTFRSLVEQTTDAGHHPLADRVEQNV
                     PVYDSDRLRILTTTPEGRRTVQGELVRALLHGPGIVVLEGAFSDTDVVDRASDTFWALI
                     EEERAAGTARGDHFAKPGANERVWSALDKMALRAPEVFADYYANDMLALIAESWLGPAY
                     QVTSQVNVVNPGGAAQSVHRDYHLGFLSQERAAAYPAHVHRLSPALTLQGAVAHCDMPV
                     ESGPTLYLPHSQKFEPGYLAWRLPQFVEYFNAHHVQLPLAKGDAAFFNPALFHAAGHNR
                     SSGIRRMANLLQVSSAFGRAMETVDREAMADALFPVLLRRKAEGASQDWLHRVVAATAE
                     GYPFPTDLDLDPPVDGLAPPSQADTVRRAVAEGWSPDRLSQELQVGSRRRRH"
     gene            4758..5804
                     /locus_tag="IE189_RS24610"
                     /old_locus_tag="GCM10010496_50100"
     CDS             4758..5804
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019073572.1"
                     /locus_tag="IE189_RS24610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_50100"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_189925014.1"
                     /transl_table=11
                     /translation="MRHPYPIREIARQAGLSTATVDRVLNHRGNVRESTIREVHQAIED
                     LDRQRTQVRIGGRTFMIDIVMQAPERFSTAVREALEAELPSLHPAVVRSRFHFRETCPP
                     AELIGILDKIAERGSQGVILKAPDLPEITAAVGRLVAVGIPVVTLVTDLPYSARLAYVG
                     IDNRAAGATAAYLLQQWLGERPGNVLTTVSRGSFRGEEERDTGFRSAMRLAQPQRSLVE
                     VTDSDGLDATQRDLVLEALERDKDIVAVYSMGGGNLATLDAFDTLGRSCAVFVAHDLDQ
                     DNTRLLRERRLSAVLHHDLGQDVRRACQTIMRADKALPDDGPTLPSAIQIVTPFNLPPH
                     VSAAPFPG"
     gene            complement(5944..6915)
                     /locus_tag="IE189_RS24615"
                     /old_locus_tag="GCM10010496_50110"
     CDS             complement(5944..6915)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020134303.1"
                     /locus_tag="IE189_RS24615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_50110"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_189925016.1"
                     /transl_table=11
                     /translation="MELEVRHLRVLCAIADAGSLHKAARELGMAQPSLSTQLRRIEQLL
                     GGPLFVRDCMGSRPTALGQVVVSRARPVLAEVSALVTETRTAAARAADGSRLRIGATAS
                     RAVPGWLSRLRACTSGVEPTLRMDVSANALLRQVTDGRLDLAFVHEVEGSPLRIPDGLC
                     LRVLVEREPQFVTMAAGHPAAAQREVRLADLAHDRWMVDATVDGEWDGVCRALRAEGIE
                     PDLLHGDYLTAYFLAAIGEVVTVSQPTALPARSDLVVRPLHGDPIGVRLLLAARTADEL
                     GVAFDELEKAYWDAARQAPVYQDWLARGTAGRSTPTLRAVGA"
     misc_feature    complement(6892..6894)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7099..7782
                     /gene="snpA"
                     /locus_tag="IE189_RS24620"
                     /old_locus_tag="GCM10010496_50120"
     CDS             7099..7782
                     /EC_number="3.4.24.77"
                     /codon_start=1
                     /gene="snpA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018548838.1"
                     /locus_tag="IE189_RS24620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_50120"
                     /product="snapalysin"
                     /protein_id="WP_189925018.1"
                     /transl_table=11
                     /translation="MKFTRTSRASAKASRRLAAIGLGVTLAAVGSALPASAQTTGSTTP
                     LRAGYTGSAEEASNNKAFFEAVLDSVARKQAANPGLQSVTVYYNASQAPSFRSQISSST
                     SIWNSSVSNVKLQATSGSADFSYYEGNDSRGSYASTNGHGSGYIFLDYAQNRQYDSVRV
                     TAHETGHVLGLPDHYSGPCSELMSGGGPGTSCTNRYPNATERSRVNQLWANGLAKALDK
                     LNKVR"
     gene            8074..8784
                     /locus_tag="IE189_RS24625"
                     /old_locus_tag="GCM10010496_50130"
     CDS             8074..8784
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019075908.1"
                     /locus_tag="IE189_RS24625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_50130"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_229901414.1"
                     /transl_table=11
                     /translation="MVPQDDTESPPKPAVVLPRRRPPRPRAAVLVLHGGQETSDSPTSP
                     RQLAALRMDPILRAVTAALPHEDVLVARVRYRLRGWNGTRADAGRDTLRALDDLDASVG
                     FVPTVLLGHSMGGRAALHAAGHPQVTGILALAPWWPSDEPVVQTAGRRIVALHGARDRV
                     TSPTDTADCVHRAQGAAARAGMAVIGGGDHAMLRRHRLWHRTTAAVVAHLLDPDAVPDP
                     LPEECYGTGSFPVL"
     gene            complement(8917..9861)
                     /locus_tag="IE189_RS24630"
                     /old_locus_tag="GCM10010496_50140"
     CDS             complement(8917..9861)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018546542.1"
                     /locus_tag="IE189_RS24630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_50140"
                     /product="hypothetical protein"
                     /protein_id="WP_307822349.1"
                     /transl_table=11
                     /translation="MPIHLADTHWETLHPPLLEAGSYAIDPAPYGPPWRHRDEVTAREA
                     AERGRFAPFDRLSDGPPDSILLAPGDLRGTRLILERAGGYCMGIDGRDGPNLACPGCDL
                     PVGTRIDDCGCWQVVRLVPHAVVRLPGPPERPLMDWAELLATGALWHRLSEYRDIPAGA
                     ALAQVVVASGGAPVEVAPGPVAELLGRALGALLPAGPGAKRLDLAGPGVGEPAADLVLV
                     PVHPQTGAMWQPRAGAVPVPMDAALWAALAFPPHRTRLPVVGGLPAGVERDDPLPPHPC
                     YPFQPSGNAFRYTLARMPAVGEPWLRTIYDRGC"
     gene            10185..12299
                     /locus_tag="IE189_RS24635"
                     /old_locus_tag="GCM10010496_50150"
     CDS             10185..12299
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035: MMPL domain-containing transport protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019071983.1"
                     /locus_tag="IE189_RS24635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_50150"
                     /product="MMPL family transporter"
                     /protein_id="WP_189925021.1"
                     /transl_table=11
                     /translation="MTVGKTTTKGVGRRRAVPWALLGLWVAVLVLVGPFAAKLADVQHD
                     RATDYLPSSADSTQVARMEEALPGGESTEMVIVYHRAGGLGADDRRVAAGQVEQIAAAH
                     ELVGGAPEGIASDDGTTLMYPVVSNEPGSDEKLRDALVEDVRGIARGQDGLSVEVGGTG
                     ALGTDAGKVYDSLGGPLLYTTVAVVALLLILIYRSPVLWLVPLVVAGIADYMSMAVAYG
                     LNQAFGTTVTGQSSGVMTILVFGAGTDYALLLVSRYREELRRIERPYEAMVATLRGCGP
                     AVLASSGTVAAGLLCLLAADLNSSRGMGPLGTVGVLCALIAMLTLLPAVLVLLGRRVFW
                     PLVPAHGSEPTQRRSLFAAMGDCAGRRPLTVLATGALLLGALALGTLNLPGPVKQEDSF
                     VTEPEAVTAMETLARAYPERGTQPIDVITPADRVDRTLATIRDTRGVESAEKGRTGNGW
                     AEISVIAKDTPQSAGETATIKSLRSELKGSYVGGDSAEQIDLEDTNSRDTKVVVPLVLV
                     SVLLILFVLLRSLVASLILVAAVVAVWGAALGIGGLVFGPVLGIEGTDPGLGLLSFVFL
                     VALGVDYGIFLMHRMREECLAGAEPADAALTALRSTGAVIASAGLVLAATFAVLMNMGL
                     VQLVELGFVIAVGVLLDTFLVRTYLVTSASVALRRKMWWPGGLSREPAPGSGPTEPTEP
                     PRQPEQVGAP"
     gene            12470..13795
                     /locus_tag="IE189_RS24640"
                     /old_locus_tag="GCM10010496_50160"
     CDS             12470..13795
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019071982.1"
                     /locus_tag="IE189_RS24640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_50160"
                     /product="sensor histidine kinase"
                     /protein_id="WP_229901407.1"
                     /transl_table=11
                     /translation="MAVVNRDPLTAPHRTRNDAFLAVGVAVLALVLASLTGDGRPLGPP
                     GWALLAGAHVPLVWRRSRPLLVLLAVAACVTLYHALDYNHAVPIPATLVALYTVAATGT
                     VRRSLLTAVVVLGPTLIINTFTNPDGALELLRISGWIIAVLFFGVDARFYRQYVASIVE
                     RAERAERTREEEARRRVVEERLRIARDLHDLLAHSITLIGVQTSVAAHVLTADPDRLDR
                     TAVAQALDGIADTCRTARGELRTTLEVLRENETGVGFARERERAAAPGSGSSSGSGLGS
                     SDGRGPLPGLDGLGALAEAARVAGAKVELSVHADGVPPSVGAAAYRIVQEALTNAVRHG
                     GRDDLTVRVGLRTAERTLRVTVTDDGAGQGTSRGAGQGHAVSGAVRNGAGHGQASGGAP
                     GFGLVGMRERARSVGGTLDAGPGPTEGFHVTAELPLPREEPS"
     gene            13804..14472
                     /locus_tag="IE189_RS24645"
                     /old_locus_tag="GCM10010496_50170"
     CDS             13804..14472
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007379596.1"
                     /locus_tag="IE189_RS24645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_50170"
                     /product="response regulator transcription factor"
                     /protein_id="WP_189925083.1"
                     /transl_table=11
                     /translation="MPIRVLLADDQTLVRASFAMLVASAGDMEVVAEAGTGRQAVDLAR
                     SAKADLVVMDIRMPDLDGIEATRLIAADEYLAGVKVLVLTTYDTDEHIVDALRAGASGF
                     LVKDIRPAELLEAIRTVAAGDSLLSPGPTSRLIARFLRAPDTAMSAVGGPHGLSERERQ
                     VLTLVARGFNNTEIAEELGLSPLTAKTHVSRIMGKLGARDRAQLVIVAYESGLVIPGAV
                     "
     gene            complement(14736..15929)
                     /locus_tag="IE189_RS24650"
                     /old_locus_tag="GCM10010496_50180"
     CDS             complement(14736..15929)
                     /EC_number="2.6.1.-"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (30-382). E-value:
                     3.3e-62. Score: 202.6. Matches aSDomain:
                     nrpspksdomains_IE189_RS24650_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009322846.1"
                     /locus_tag="IE189_RS24650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_50180"
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="WP_189925024.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.4e-61, bitscore:
                     202.7, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 1.5e-08, bitscore:
                     28.1, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1e-07, bitscore:
                     25.6, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISQRARAIAPFYAMEFGKQAAELEAAGHHVVKLSLGEPDFGAP
                     PAVLEAMRNAMDGRPMAYTAALGLPALRQAIARFYADRHGVEVDPARVAVTAGASAALV
                     LATAALVDPGDEVLIADPSYPCNRQIMESFGARVTLVPTTPASRFQLDAESVGAHWTDD
                     TRGVMIASPSNPTGTSVPADELRTLCALARERAAWRLVDEIYLDLGDPDDHGRPPGTAL
                     AHDPDAVVINSFSKYFGMTGWRLGWCVVPEALVPALERLAQNYFLCASAPAQHAALACF
                     TPESLAVAEARRVEFAERRALVLDGLERIGLPVPVPPDGAFYAYFDVAATGLSSWDFCA
                     RALSEAHVALTPGRDFGVGTAESHVRLSYAASAGELREGLARLGKFVSALGPTASSL"
     aSDomain        complement(14784..15839)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS24650_Aminotran_1_2.1"
                     /evalue="3.30E-62"
                     /label="IE189_RS24650_Aminotran_1_2.1"
                     /locus_tag="IE189_RS24650"
                     /protein_end="382"
                     /protein_start="30"
                     /score="202.6"
                     /tool="antismash"
                     /translation="HVVKLSLGEPDFGAPPAVLEAMRNAMDGRPMAYTAALGLPALRQA
                     IARFYADRHGVEVDPARVAVTAGASAALVLATAALVDPGDEVLIADPSYPCNRQIMESF
                     GARVTLVPTTPASRFQLDAESVGAHWTDDTRGVMIASPSNPTGTSVPADELRTLCALAR
                     ERAAWRLVDEIYLDLGDPDDHGRPPGTALAHDPDAVVINSFSKYFGMTGWRLGWCVVPE
                     ALVPALERLAQNYFLCASAPAQHAALACFTPESLAVAEARRVEFAERRALVLDGLERIG
                     LPVPVPPDGAFYAYFDVAATGLSSWDFCARALSEAHVALTPGRDFGVGTAESHVRLSYA
                     ASAGELREGLAR"
     gene            <16181..16315
                     /locus_tag="IE189_RS39210"
                     /pseudo=""
     CDS             <16181..16315
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012377440.1"
                     /locus_tag="IE189_RS39210"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="ATAGAPVERGVTLLRAWRILRKSRSNPNRMQSIAAPLLTLERQV"
     gene            complement(16838..17083)
                     /locus_tag="IE189_RS24655"
                     /old_locus_tag="GCM10010496_50190"
     CDS             complement(16838..17083)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE189_RS24655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010496_50190"
                     /product="hypothetical protein"
                     /protein_id="WP_189925025.1"
                     /transl_table=11
                     /translation="MVGLDSQGAVEAQGVGGAAQLQSATDLVAGEPAFGKPQFTVTVQH
                     RGGRMRLPLAEPLIARPVDDRRGLVVGELPAVRAAA"
     misc_feature    17150..17163
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.67"
                     /tool="antismash"
     gene            17641..18987
                     /locus_tag="IE189_RS24660"
                     /old_locus_tag="GCM10010496_50210"
     CDS             17641..18987
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012422.4"
                     /locus_tag="IE189_RS24660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_50210"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_189925026.1"
                     /transl_table=11
                     /translation="MPQTSFLADSARTFSDAGTCVKCQLIRQAIALWMNGWSDRSLHLA
                     EESAAMTAGDSSCECDLHAVMWLAFVLTTRGESDRVRKLLHHAESGDSSLFGPVMVPAG
                     LSLARSHLAFMAGDLDVAAALSEQVLAQAEGSREIRIASHLILALIALRRAEVNAASSH
                     MQMISDDAFMGRLTVLAGPCAWVNVRMREAQWGAEGVAPVIEELVDFGPVSRKIFLSQS
                     AAAPWIVRLALKFDQKATAHKAVKLAQKLAERNPQHHVLAASALHAQSLFERNLVGLRL
                     AAKMHVHPWARASTTEDIGKFLAHERSQQDQAIGIFEQSADAYIKVGAPRDALRIKKRL
                     WDLGVRHHQSRWRATPPAAIGNLTETEAKVAQLVAQGMTNTQTAKNLFISPHTVAYHLK
                     KIFCKLQISSRVELARDWTTIEGPQGGPRTADGGTAGNGRGSRAVERGL"
     gene            19147..19779
                     /locus_tag="IE189_RS24665"
                     /old_locus_tag="GCM10010496_50220"
     CDS             19147..19779
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020551380.1"
                     /locus_tag="IE189_RS24665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_50220"
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="WP_189925027.1"
                     /transl_table=11
                     /translation="MSSLLHIDASIRHEGSTSRQLTSYFVTRWRQNHPDGGYVYRDLAA
                     EPIPHLTHPVREYLLDPSRDHGQTDEEKALVHTVASEVADADTILLGVPMYNYTIPSHV
                     KAWIDLLVSPAHMVLPGADSGPLSGKSVIVVTARGGSYAPGTPREGQDHQEPYLRDVLK
                     AIGLADNLTFVNAELTLAATVPALAELKPLGEKSLATAQETLRKLAA"
     gene            20001..>24868
                     /locus_tag="IE189_RS24670"
     CDS             20001..>24868
                     /NRPS_PKS="Domain: CAL_domain (33-446). E-value: 1.1e-212.
                     Score: 699.9. Matches aSDomain:
                     nrpspksdomains_IE189_RS24670_CAL_domain.1"
                     /NRPS_PKS="Domain: ACP (952-1022). E-value: 1.8e-26. Score:
                     84.2. Matches aSDomain: nrpspksdomains_IE189_RS24670_ACP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (1048-1473). E-value:
                     4.5e-181. Score: 594.3. Matches aSDomain:
                     nrpspksdomains_IE189_RS24670_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012711.4"
                     /locus_tag="IE189_RS24670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type I polyketide synthase"
                     /protein_id="WP_189925028.1"
                     /sec_met_domain="AMP-binding (E-value: 4e-114, bitscore:
                     375.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.5e-10, bitscore:
                     34.9, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 8e-228, bitscore: 750.4,
                     seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 2.2e-92, bitscore:
                     303.3, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLPDLITPLPVILSENAGRFPDKIAFEDDRYAVTYRELDARTRRL
                     AGHLVGLGVRRGDRVALCLGNSVAMVESYLAVVRAGGIGVPVNPQAAPAEIAYLLADSE
                     ATLALTGTAHAETFVQSLPRVTRRVSVVVAGAPDAGRLLPPGTVPFEELATTEPADEPP
                     DDLALDEVAWMFYTSGTTGRPKGVLSTQRNCLFSVASCYIPVPGLSEHDRVLWPLPLFH
                     SLSHIACVLSVTVSGATARIMDGSSADDILTALREDRSTFLAGVPTTYHHLVDRARRTG
                     LSLPDLRVGLVGGAVTGPGLRRSFEETFGIPLVDAYGSTETCGAITVNPPDGPVVEGSC
                     GLPVPGVGVRIVDPRTGQDVPAGHEGEVWVSGPNVMVGYHNNPQGTAEALQDGWFRTGD
                     LARRDEAGYFTISGRLKDVIIRGGENIHPDEIEAALRVAEGVADVAVTGMAHDTLGEVP
                     VAWVVPGPAGVDLARLLDRCRAQLSAYKLPERVYEARAIPRTASGKVVRRLLPDLPARL
                     RYAADGHHEGLMLRDWSKVAVSSDAPEGLRWAVVGRTAATDGLVAALRKAGVADVRHYA
                     DLSASRTTPDAAADVTVLAEAEAEAEADADTWAPAREGVGRETGSRLVVLTRGAMGVTD
                     RDGTPDGAEVALWAAARAAQADPGDGAPLTIVDVEAGTPGSECAVALITAVSSGLPQLA
                     VRDGELMRPRLVRLPVADRPDPAMPGIEGVVVVTGADTRTGSVLARHLVTGHGTRHLVL
                     VQATHTNDRWSQDEPLPQGVDIVRVVADGSDTLELYEALTRTGPVTAVVHTADDPELAR
                     ALHDFTADDDVAAFVVVTDAAALVGASESDGLASTVVTAALTEAVVRDRRLHGLPGSLL
                     ALGRPDEGPAAFDALIETGSPALLALSPSTINPGDRVRTLLGTLTDQEPRATARADETI
                     TAALRARLADLDERGQLALLGEMIRNETAAVRTHASPEPIPAGRSFRDLGLGSLAVVEL
                     RNRLTGRTGLRLPTTVTFDHPTPEALAAHLRARILGLHDPAGEATADRDRTGAAGPAEP
                     IAIVGMACRLPGGVASPQDLWRLVSEGRDGVSGFPEDRGWDLDGLFDADPEKTGTSYVD
                     QGGFLHEAGLFDAGFFGISPREALAMDPQQRLLLETSWEALERAGFDPGTLKGRDVGIF
                     SGLMGQGYGLSGAAPAELEGFGETGKASSVASGRVSYVFGFEGPAITVDTACSSSLVAM
                     HLAVQSLRQGECSMALAGGATVMAEPSTFVGFSRQRALSSDGRCKSYADAADGTGWAEG
                     AGVVVLERLSEARRNGHRILAVIRGSAVNQDGASNGLTAPNGLAQQRVIRQALAAAGLS
                     AAEVDVVEGHGTGTVLGDPIEAQALLATYGSDREPGSPLWLGSLKSNIGHTQAAAGVAG
                     VIKMVQALRYGVMPPTLHVDAPSSKVDWSAGAVQVLTEARAWPETGRLRRAGVSSFGLS
                     GTNAHLILEQAPETEPVDARPVESEPTAEVVDGVVPLVLSAASAASLVGQAERLASFAE
                     STEVSLPHVAGALVAQRAVLSERAVVVAEPGVEALAGLGALARGESKPGVVTGSAVGAG
                     RTVVVFPGQGSQWVGMGRELLDSSTVFAERVGECAAALERWVD"
     aSDomain        20100..21338
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS24670_CAL_domain.1"
                     /evalue="1.10E-212"
                     /label="IE189_RS24670_CAL_domain.1"
                     /locus_tag="IE189_RS24670"
                     /protein_end="446"
                     /protein_start="33"
                     /score="699.9"
                     /specificity="Minowa: AHBA"
                     /tool="antismash"
                     /translation="TYRELDARTRRLAGHLVGLGVRRGDRVALCLGNSVAMVESYLAVV
                     RAGGIGVPVNPQAAPAEIAYLLADSEATLALTGTAHAETFVQSLPRVTRRVSVVVAGAP
                     DAGRLLPPGTVPFEELATTEPADEPPDDLALDEVAWMFYTSGTTGRPKGVLSTQRNCLF
                     SVASCYIPVPGLSEHDRVLWPLPLFHSLSHIACVLSVTVSGATARIMDGSSADDILTAL
                     REDRSTFLAGVPTTYHHLVDRARRTGLSLPDLRVGLVGGAVTGPGLRRSFEETFGIPLV
                     DAYGSTETCGAITVNPPDGPVVEGSCGLPVPGVGVRIVDPRTGQDVPAGHEGEVWVSGP
                     NVMVGYHNNPQGTAEALQDGWFRTGDLARRDEAGYFTISGRLKDVIIRGGENIHPDEIE
                     AALRVAEGVADVAV"
     aSModule        20100..23066
                     /complete
                     /domains="nrpspksdomains_IE189_RS24670_CAL_domain.1"
                     /domains="nrpspksdomains_IE189_RS24670_ACP.1"
                     /locus_tags="IE189_RS24670"
                     /monomer_pairings="AHBA -> AHBA"
                     /starter_module
                     /tool="antismash"
                     /type="cal"
     CDS_motif       20514..20567
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS24670_0001"
                     /evalue="5.40E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="IE189_RS24670"
                     /protein_end="189"
                     /protein_start="171"
                     /score="19.1"
                     /tool="antismash"
                     /translation="AWMFYTSGTTGRPKGVLS"
     CDS_motif       21081..21167
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS24670_0002"
                     /evalue="4.00E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="IE189_RS24670"
                     /protein_end="389"
                     /protein_start="360"
                     /score="28.8"
                     /tool="antismash"
                     /translation="PAGHEGEVWVSGPNVMVGYHNNPQGTAEA"
     CDS_motif       22038..22070
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS24670_0003"
                     /evalue="6.40E+01"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE189_RS24670"
                     /protein_end="690"
                     /protein_start="679"
                     /score="-2.4"
                     /tool="antismash"
                     /translation="VALITAVSSGL"
     aSDomain        22857..23066
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS24670_ACP.1"
                     /evalue="1.80E-26"
                     /label="IE189_RS24670_ACP.1"
                     /locus_tag="IE189_RS24670"
                     /protein_end="1022"
                     /protein_start="952"
                     /score="84.2"
                     /tool="antismash"
                     /translation="MIRNETAAVRTHASPEPIPAGRSFRDLGLGSLAVVELRNRLTGRT
                     GLRLPTTVTFDHPTPEALAAHLRAR"
     aSDomain        23145..24419
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS24670_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="4.50E-181"
                     /label="IE189_RS24670_PKS_KS.1"
                     /locus_tag="IE189_RS24670"
                     /protein_end="1473"
                     /protein_start="1048"
                     /score="594.3"
                     /tool="antismash"
                     /translation="IAIVGMACRLPGGVASPQDLWRLVSEGRDGVSGFPEDRGWDLDGL
                     FDADPEKTGTSYVDQGGFLHEAGLFDAGFFGISPREALAMDPQQRLLLETSWEALERAG
                     FDPGTLKGRDVGIFSGLMGQGYGLSGAAPAELEGFGETGKASSVASGRVSYVFGFEGPA
                     ITVDTACSSSLVAMHLAVQSLRQGECSMALAGGATVMAEPSTFVGFSRQRALSSDGRCK
                     SYADAADGTGWAEGAGVVVLERLSEARRNGHRILAVIRGSAVNQDGASNGLTAPNGLAQ
                     QRVIRQALAAAGLSAAEVDVVEGHGTGTVLGDPIEAQALLATYGSDREPGSPLWLGSLK
                     SNIGHTQAAAGVAGVIKMVQALRYGVMPPTLHVDAPSSKVDWSAGAVQVLTEARAWPET
                     GRLRRAGVSSFGLSGTNAHLILEQAP"
     CDS_motif       23625..23672
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS24670_0004"
                     /evalue="8.30E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE189_RS24670"
                     /protein_end="1224"
                     /protein_start="1208"
                     /score="20.9"
                     /tool="antismash"
                     /translation="GPAITVDTACSSSLVA"
     CDS_motif       24048..24092
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS24670_0005"
                     /evalue="4.00E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE189_RS24670"
                     /protein_end="1364"
                     /protein_start="1349"
                     /score="9.9"
                     /tool="antismash"
                     /translation="VEGHGTGTVLGDPIE"
     CDS_motif       24153..24197
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS24670_0006"
                     /evalue="1.90E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="IE189_RS24670"
                     /protein_end="1399"
                     /protein_start="1384"
                     /score="10.9"
                     /tool="antismash"
                     /translation="GSLKSNIGHTQAAAG"
     CDS_motif       24744..24800
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS24670_0007"
                     /evalue="2.90E-09"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="IE189_RS24670"
                     /protein_end="1600"
                     /protein_start="1581"
                     /score="28.6"
                     /tool="antismash"
                     /translation="VVVFPGQGSQWVGMGRELL"
ORIGIN
        1 atgaccgtcg cggacggccg gttcggccgt actgctgaac acacaagtag ggatacgcat
       61 gtcttccatc gttgcgaggc gtcacttcga ccgggtcaac tgcgcctgga cgccgtagtg
      121 gtcggacagg tgggtctggc ggccgtcggg cagtgtcacc tcttcctgga acaccaagtc
      181 ggcgctgccg gtcagtgtct ctccggctgc ggaccggatc agtatgtggt ccagggccgg
      241 cggtgacggc catccaggtg tgggccggta ggtgggacgc gtgtcgccgg cgaggacgtc
      301 gctcagcccg gcggcggtga tgaagtcggt gagcgccgcc gactcgcgcg ggaggttcag
      361 gtcaccgacc acggcgacgg gcagggacgg gtcgacggcc gcgatcagcg aggcgagccg
      421 ggccagttcg ccggccgcga tccgcgtgta ccggttcgtg ggcgaccagt cgtcgtcgcg
      481 gttggccgac aagtgggtgt tcacgacgac cagttcgccc gccggggtgg cgacggacgc
      541 cagctgggcg cccttgcgca tgaggagttc gccgcgtacc ggacccgtcg tcgggtagcg
      601 cacgaagcgg tatcggctga tcggccaccg ggacagcagc accaggccgc ccttgagcag
      661 cgccgtgccc gagcaggcga cgtaccggta cgcgggagcg gcgcggcgga gcagccgggc
      721 gtggcggcgg tacatgacct cctgcaagca gacgatgtcg aggtcggacc ggtcgagggc
      781 cgctccgagc gcacgcagcc gggccgggac atcgccggtg tagagggcgt tcatggtgag
      841 cagccgcatg gccttcacaa gcgtgtcgct ttctgtccgg tgtccgccga gcggggcggt
      901 gagccgtgta gcagctcacg gcgttgcgcg tattcggtac gtactcaccg cgaactctcg
      961 cagagagcaa ccgggttcac gccaggggga atccacgggc gaacagctgg tccgcccgcc
     1021 gacctcggcg atgcccctct tccgtgccct gctcagcccg atacgggcga gttcagacgc
     1081 tcgcggaaag cccggttcgt ggccatcagg ccgtcgaggg cgtcgcgggt gcggaggagc
     1141 tcggcgatgt gctcggagag ccgttcgcgc tcctcggcca tccggagcag cgcggcatcg
     1201 gcgttctccg cgctgggcga gtcgacgcac ggcagcagtt cggcgatcgt ccggctggac
     1261 agcccggcgg tgtacatccg ctggaggaac gtgacccgct cgatgtggac ctcggtgtag
     1321 tgccgctgtc cgccggtact gcgcgcgctg gtgagcaggc cctgttcctc gtagtagcga
     1381 agggaccgga cgctgacccc ggctcgcgcc gcgagctccc cgatacgcat gccgtcccgc
     1441 cttccccgtt gtgatccgga acacaaccct tgcacctgac gtcaatgtca ggttctagcg
     1501 tagccgaggc gcccggcacc gggcgacgga tcacgaagga gatatgacgt ggcaagcctc
     1561 ctcagcagct accggctcgg cgatctggcg ctgcccaacc gggtggtgat ggccccgatg
     1621 agccgcgtgc gggccgcggc gggcggtctg gcgaccccgt ccatggcgcg ttactacgcg
     1681 cagcgggcca ccgccggtct gatagtcagc gagggcgtac agccgagcct gctcggtcag
     1741 tccaatcccg gcactccggg gctgcacacc gacgaccagg tggcgtcctg gcgcccggtg
     1801 accgacgcgg tgcacgccaa cggcgggcgg atcttcgccc agatcatgca cggcggacgg
     1861 gtctcgcacc ccgacaccac cggcatgcgg cccgtcggcc cctccgccgt cgcggccgtc
     1921 ggtgaggtgt tcacgcctac cgggccccag ccggtaccgc ttccccgcgc cctggagacg
     1981 gccgaggttc ccgagcagat ccggtcgtac gcgcaggccg cgcgccgtgc cgtcgacgcc
     2041 gggttcgacg gtgtcgaact gcacggggcc aacggctatc tgatctcgca gttcctctcg
     2101 gccaacgcca atctgcgcac ggaccgttac ggcggttcgg tgaccaaccg gatccggttc
     2161 gccgtggagg cggtcgccgc gaccgtcgag gccgtcgggg cggcccggac cgggatccgg
     2221 ctctctcccg gtgggccctt ctggggcatc gaggagaccg acgtcgccga gcactacacc
     2281 gcactcctcg gcgagttgtc ccgcctcgac ctggcctatg tccatctcga ggccacggcc
     2341 gacgaggaga cgctgctcgg gctgcgccga gtctggccgg gcactctggt catgaacccg
     2401 gtgctgcccc tgggacccaa gcagaccggc cgtgccgaag cggaccactg gctgggtctc
     2461 ggagccgatc tcatcagttt cggacgggcc ttcatcgcca atcccgacct ggtggagcgg
     2521 ctgcgcaccg gcctgccgat cgctccggcg gacgagagca cgtacttcca gggcggcgac
     2581 gacggctatc tcacctaccc ggcctaccag cacgcgcagt gacatcgcgg ggagcgccga
     2641 cgacgtcgtg gaagggcgtc caggccgccg tcgatcttct cggcgtccgg ctcagtcctg
     2701 gccgccgaac acgttctggt cccagtcgat gaccgagccg gtcaccaccc cgctgcgatc
     2761 cgagaggagg aagacgacga actcggcgat ctcgtcgacc tgtccgagct tgcccatggg
     2821 ctgggccgcg gcggctctcg cccgccagtc ggcgcccgcg ccgtggaagg cacgctgggt
     2881 cgcgtcctcg ccctcggtgt ccgtccagcc gatgtcgagg ccgttgatgc ggatgcggtc
     2941 ccagcgatgt gcgtgggcgg cgttgcgggt cagtccggcc agacctgcct tggcggcgga
     3001 gtagggggcc aggtgcggag gcccgccacg ggcgcagttg gagccgatgt tgacgatcgt
     3061 gcccggcgcc cggcgggcct tcatgtcggt caccgccgcc tgcatcgcga agaacggcgc
     3121 cctcaggttg atcgccatgt gccggtcgaa cagttccggt gtggtgtcca ggagcgagcc
     3181 acgcgatgtc agccctgccg cgttgaccag gcagtcgatg cgtccgtgag cgctcacggt
     3241 ccgtacgacg ctgtcgcggg cctgtgccgg atcggcgagg tccgcccgca tgaagtgcgc
     3301 gccggtgtcc tcggcgagct tctcgcccaa ctcgacccgg cggccggtga agagcacggt
     3361 cgcgcccgcc ccgagggccg cccgcacgat acccgcgccg acgccctggc tgccgccgtt
     3421 gaccaggacg atcctgtcct gaaggagtgc catgagtgtg gagtcccttt cagtggcgtc
     3481 gacgcctgga gccgacctgg agttcctggc tcagccggtc gggggaccag ccctcggcca
     3541 cggctcgccg gacggtgtcc gcctgggagg gcggggcgag tccgtcgacc ggggggtcga
     3601 ggtccaggtc ggtggggaag gggtagccct cggcggtggc ggcgaccacg cggtgcagcc
     3661 agtcctgcga agctccctcc gccttgcggc gcagaagcac cgggaagagg gcgtcggcca
     3721 tggcctcgcg gtccaccgtc tccatcgcgc ggccgaaggc ggaggagacc tgtagcaggt
     3781 tggccatacg tcggatcccg ctcgagcggt tgtggcccgc ggcgtggaag agggcggggt
     3841 tgaagaaggc ggcgtcgccc ttcgccaggg ggagctggac gtgatgggcg ttgaagtatt
     3901 cgacgaactg cggcagccgc caggccagat agcccggctc gaacttctgc gagtgaggca
     3961 gatacagcgt cgggcctgac tcgacgggca tgtcgcagtg ggcgacggcg ccctgcaagg
     4021 tcagcgcggg ggagaggcgg tggacgtgcg ccgggtaggc cgccgcgcgc tcctgggaga
     4081 ggaagccgag gtggtagtcg cggtgcacgc tctgcgcggc cccgccggga ttgacgacgt
     4141 tgacctgcga ggtcacctga taggcggggc cgagccagct ctcggcgatg agggcgagca
     4201 tgtcgttggc gtagtagtcg gcgaacacct cgggagcccg aagagccatc ttgtccaggg
     4261 cgctccagac acgttcgttg gcgcccggct tggcgaagtg gtcgccgcgg gcggtgccgg
     4321 cggcgcgttc ttcttcgatc agcgcccaga aggtgtcgga cgccctgtcc acgacgtccg
     4381 tgtcggagaa ggcgccctcg aggaccacga tgccgggtcc gtggagcagc gcccgcacca
     4441 gctcgccctg tacggtgcga cgcccctcgg gggtggtggt cagaatacgc agccggtcac
     4501 tgtcgtagac cggcacgttc tgctcgaccc ggtcggccag ggggtggtga ccggcatcgg
     4561 tggtctgctc gacgagcgag cggaacgtgt cgagatcaca gtcggcctcg gtgagccagg
     4621 tcagtgatcg cacggccgtc ggagacatcc cgggtccttt cgcagtgcct gcttttctgc
     4681 cagtcttgag aacccgaacc catcattcaa ccctcagcaa tgcatcaaaa gtccatcatc
     4741 gtcaccggga atccgtcatg cgccatccct atccgatcag ggaaatcgcc cgccaggccg
     4801 gactgagcac ggccacggtc gatcgcgtcc tcaaccaccg gggcaacgtg cgggagagca
     4861 cgatccgtga ggtgcaccag gccattgaag acctggaccg ccagcggacc caggtccgca
     4921 tcggcggccg cactttcatg atcgacatcg tgatgcaggc accggagcgc ttctccaccg
     4981 ctgtgcggga ggcgctggag gccgaactgc cctccctgca ccccgcggtc gtgcgctcac
     5041 gcttccactt ccgcgagacc tgccctcccg ccgaactgat cggcatcctc gacaaaatag
     5101 ccgagcgcgg ttcgcaggga gtgatcctca aggccccgga cctgccggag atcacagccg
     5161 ccgtggggcg gctcgtcgcc gtcggcattc ccgtcgtcac cctggtgacc gacctgccgt
     5221 acagcgcccg cctggcatac gtcggcatcg acaaccgtgc ggcgggggcc actgccgcgt
     5281 acctccttca gcagtggctc ggcgagcggc ccggcaacgt gctcaccacc gtcagccggg
     5341 gctccttccg cggtgaggag gagcgcgaca cgggcttccg cagcgcgatg cgcctggcgc
     5401 agccacagcg ctccctcgta gaggtcaccg acagcgacgg cctggacgcc actcagcgcg
     5461 atctggttct cgaggcactc gagcgcgaca aggacatcgt cgccgtctac tccatgggcg
     5521 gcggcaacct cgcgaccctc gacgccttcg acaccctcgg gcgttcgtgt gccgtgttcg
     5581 tcgcgcacga cctcgaccag gacaacaccc gactgctgcg cgaacgccgc ctgtccgcgg
     5641 tgctccacca cgacctgggc caggacgtcc gccgcgcctg ccagaccatc atgcgcgccg
     5701 acaaggcact tccggacgac ggcccgacgc tcccctcggc gatccagatc gtcacgccgt
     5761 tcaacctgcc gccccacgtg agcgccgcac cgtttccggg gtgacgcggc ggcccggtcc
     5821 ggccgcctgg ttttcgagac cgccgacgcg ctcaggccca ccgactgccc cggacggtga
     5881 ggtccggggc gatgccgagc cccggccctg ggcgggcgcc ggcgagaggt gatgtcccgc
     5941 tgctcaggcg cccaccgcgc gcagtgtcgg ggtggaccgt ccggcggtgc cgcgcgccag
     6001 ccagtcctgg tacaccggcg cctgacgggc cgcgtcccag taggccttct ccaattcgtc
     6061 gaacgcgacg ccgagttcgt ccgccgtccg ggccgcgagc agcagacgga ctccgatcgg
     6121 atcaccgtgc agaggccgca ccaccaggtc ggaacgagcc ggcagggcgg tcggctgact
     6181 gaccgtgacg acctcgccta tggccgccag gaagtaggcg gtgaggtagt cgccgtgcag
     6241 caggtcgggc tcgatcccct cggcgcgcag cgcccggcac actccgtccc actcgccgtc
     6301 gaccgtggcg tccaccatcc agcggtcgtg cgcgaggtcc gcgagacgca cctcgcgctg
     6361 agccgccgcg ggatggccgg cggccatggt gacgaactgg ggttcgcgct ccaccaggac
     6421 ccgcaggcac agcccgtccg ggatgcgcag cgggctgccc tcgacctcgt gcacgaatgc
     6481 caggtccagc ctgccgtcgg tcacctgccg cagcagggcg ttcgcggaca cgtccatccg
     6541 cagggtgggc tcgacgccgg acgtgcaggc gcgcagtcgg ctcagccagc ccgggaccgc
     6601 ccggctggcc gtggcgccga tgcgcagccg ggaaccgtcc gccgcgcggg cggccgcggt
     6661 cctggtctcg gtcaccagcg cggagacctc ggcgagcacg ggccgggcgc ggctcaccac
     6721 gacctgcccc agcgccgtgg ggcggctgcc catgcagtcc cggacgaaga gcggaccacc
     6781 cagcaactgc tcgatgcggc gcagctgagt actcaacgag ggctgagcca tgcccagttc
     6841 acgagccgcc ttgtgcagac tgccggcatc ggcgatggcg cacagcacac gtaagtgcct
     6901 cacctcgagc tccatgcgcg gagcctagag gctgtgctcg ctgaggcgcc agatgttcaa
     6961 aagccaacgt aacaacacga gttgccccga tagccctgag ctatcggcag ttgccatcat
     7021 cccctccgcc gcccagctgt cccacactcg ggtcgaccga tcgttcacca ccccacatga
     7081 acgagtagga gcccccacat gaagttcacc cgtacgtccc gtgcgtccgc gaaggcctcc
     7141 aggagactgg cggcgatcgg cctgggcgtg acgctggcag ccgtcggcag cgccctcccc
     7201 gcgagtgccc agaccaccgg gtccaccacg cccctccgcg ccggctacac cggttcggcc
     7261 gaggaggcgt cgaacaacaa ggccttcttc gaggccgtgc tcgactcggt cgccaggaag
     7321 caggctgcca acccgggcct ccagtcggtg accgtctact acaacgcctc ccaggcgccg
     7381 agcttccgct cccagatatc gagctccacc tcgatctgga acagctccgt gagcaacgtc
     7441 aagcttcagg ccacctccgg gagcgccgac ttctcgtact acgagggcaa cgactcccgg
     7501 ggctcgtacg cctccaccaa cggccacggt agcggctaca tcttcctcga ctacgcgcag
     7561 aaccggcagt acgactcggt ccgcgtcacc gcgcacgaga ccggtcacgt gctgggcctg
     7621 ccggaccact acagcggccc gtgcagcgaa ctgatgtcgg gcggcggacc cggtacgtcc
     7681 tgcaccaacc gctaccccaa cgcgaccgaa cggtcgcgcg tcaaccagct ctgggccaac
     7741 ggtctcgcca aggccctcga caagctgaac aaggtgcgct gacagcccga gggcttcctc
     7801 agccccgcgc cccctcgccc gagccggaaa cgggccgtgc ccccagggca cggcccgctt
     7861 gcgtgcgcgc agacgcgggc agacgcgtgc agacgcgtgc agacagagcc cgcccggagg
     7921 ccgcggcccg ccgcgccgca caccgaccgc ggcacgtacc cggcgcccct tcttcccctg
     7981 gccgccgaag ccgggcgcct accgggggcg acggcgacgg cccttccggg ggaagatgca
     8041 cgagttgcga ctcacggtga gaaggagacc ccgatcgtgc cgcaggacga caccgagtcc
     8101 cctccgaagc cggcggtcgt gctgccccga cggcgtccgc cacggccccg ggccgccgtc
     8161 ctcgtgctgc acggtgggca ggagacgagc gacagcccca ccagtccgcg gcagctggcc
     8221 gccctgcgga tggacccgat cctgcgggcg gtgaccgccg cgctgcccca tgaggacgtc
     8281 ctggtcgcac gggtgcgtta ccgcctgcgc ggctggaacg gcacccgtgc cgacgcgggg
     8341 cgggacaccc tgcgggccct ggacgacctc gacgcgtccg tgggtttcgt ccccaccgtg
     8401 ctgctcggcc actccatggg cggccgggca gccctgcacg cggccggaca cccacaggtc
     8461 acaggcatcc tcgcgctcgc gccgtggtgg ccgtcggacg agcccgtcgt ccagacggcg
     8521 ggacggcgca tcgtcgccct gcacggtgcc cgggaccgcg tcacctcgcc caccgacaca
     8581 gccgactgcg tacaccgcgc ccagggcgcc gcggcccggg cgggcatggc cgtcatcggc
     8641 ggcggtgacc acgccatgct gcgccgacac cgcctctggc accggaccac cgcggctgtc
     8701 gtcgcccacc tcctcgaccc cgacgccgta ccggatccgc tgcccgagga gtgctacggg
     8761 accggatcct tccccgtgct ctgagcgcgc tgcgttcacg cagacacacg gcctcgccgg
     8821 aggcggccgg gccggtggcc gtggccccgt gaagcacacc gccggcgaag tcccgccccc
     8881 gaggggcgga gaagcggaag cgtgcgtgag ttccgatcag catccccggt cgtagatcgt
     8941 ccgcagccac ggttctccga cggcgggcat ccgcgccagc gtgtaccgga aggcattgcc
     9001 ggacggctgg aacgggtagc acgggtgcgg aggcagggga tcgtcccgct ccacgcctgc
     9061 cggcagcccg ccgaccaccg gcagccgggt ccggtggggc gggaaggcga gcgcggccca
     9121 gagcgcggca tccatgggta ccggcaccgc cccggcgcgc ggctgccaca tcgctccggt
     9181 ctgcgggtgg accggcacca gcaccaggtc agcggccggc tcaccgaccc ccggacccgc
     9241 caggtccagc cgcttcgcac ccggcccggc gggcaacagc gcgccgagtg cccgaccgag
     9301 gagctccgcc accggtccgg gtgccacctc gaccggcgcg cccccggagg ccaccaccac
     9361 ctgggcgaga gccgcgcccg ccgggatgtc ccggtactcg ctcagccggt gccacagcgc
     9421 gcccgtggcc agcaactccg cccagtccat gagcggccgc tccggcgggc cgggcagacg
     9481 caccacggcg tgcgggacga gccggacgac ctgccagcac ccgcagtcgt cgatcctcgt
     9541 tccgaccggc agatcacagc ccgggcaggc gaggttcggc ccgtccctcc cgtcgatccc
     9601 catgcagtag cccccggccc gctcgaggat cagcctggtg ccgcgcaggt cgccgggcgc
     9661 gaggaggatg ctgtccggcg gcccgtcgga cagccggtcg aacggcgcga agcgccccct
     9721 ctccgccgcc tcgcgcgccg tgacctcgtc ccgatgccgc cacggtggcc cgtacggtgc
     9781 ggggtcgatc gcgtaggacc cggcctccag cagcggcggg tgcagcgtct cccagtgggt
     9841 gtccgccagg tggatcggca tcgccacccg cgacaccgcc gtcgtcagga ccgcaccaca
     9901 gcccgcacac ccgaacaccg ccaagccggc ccctcccgcc gtcgaaccct tgcatcccac
     9961 caaccggacg gaccggcggg caaagggttt tcccggccca ctccggggtc caaatacggg
    10021 cgccgcgctc gggtatgccg gactactccc gcgggagtaa cgcgcacccc ccgtcacccc
    10081 aggcagtacc cgcaggctcc ccctcccgtc cgacgaaaac cccttcccgt gccggaaggc
    10141 tgacagctgg aaaaggtcgt agtcgtagcg agggagatcc gctcatgacg gtcgggaaga
    10201 caaccacgaa gggcgtggga cgcagacggg ccgtgccctg ggcgctgctc gggctatggg
    10261 tggccgtgct cgtgctggtc ggcccgttcg cggcgaagct cgccgacgtg cagcacgacc
    10321 gggccaccga ctacctgccc tccagcgccg attcgaccca agtggcccgg atggaggaag
    10381 cgctgcctgg gggcgagagc accgagatgg tgatcgtgta tcaccgggcc ggcgggctgg
    10441 gcgccgacga ccggcgggtc gcggccgggc aggtcgagca gatcgccgcg gcgcacgagc
    10501 tggtcggcgg agcgcccgag gggatcgcgt ccgacgacgg tacgaccctc atgtaccccg
    10561 tcgtcagcaa cgagcccggc agcgacgaga agctgcggga cgcgctcgtc gaggacgtcc
    10621 ggggcatcgc ccgcggccag gacgggctga gcgtcgaggt gggcggcacc ggagcgctcg
    10681 gcaccgacgc cgggaaggtc tacgactcac tcggcgggcc gctgctctac accaccgtcg
    10741 ccgtcgtcgc cctcctgctc atcctgatct accgcagccc ggtgctgtgg ctcgtgccgc
    10801 tcgtcgtcgc cggcatcgcc gactacatgt ccatggctgt cgcgtacggg ctgaaccagg
    10861 ccttcggtac caccgtcacg ggccagagct ccggcgtgat gacgatcctc gtgttcggcg
    10921 cgggcaccga ctacgccctg ctcctcgtct cccgctaccg ggaggaactg cggcgcatcg
    10981 agcgcccgta cgaggccatg gtcgccaccc tgcgcggctg cgggcccgcc gtgctcgcct
    11041 cctccggcac cgtcgccgcc ggcctgctgt gcctgctcgc cgccgacctc aacagcagcc
    11101 gcggcatggg cccgctcggc acggtcggtg tgctgtgcgc gctgatcgcg atgctgacgc
    11161 tgctccccgc cgttctcgtc ctgctcgggc ggcgggtctt ctggccgctc gtacccgccc
    11221 acggcagcga acccacacag cggcggagtc tcttcgccgc gatgggcgac tgtgccggac
    11281 gcaggccgct gaccgtgctc gcgaccggag ccctcctgct cggcgcactg gccctcggca
    11341 cgctcaacct gccgggaccg gtgaaacagg aggactcctt cgtcaccgag ccggaggccg
    11401 tcaccgccat ggagaccctc gcccgggcct accccgagcg cggcacccag cccatcgacg
    11461 tgatcacccc ggcggaccgc gtcgaccgga ccctcgcgac gatccgggac acccggggag
    11521 tcgagagcgc cgagaagggc cgtaccggga acggctgggc cgagatctcc gtcatcgcga
    11581 aggacacacc ccagtcggcg ggggagaccg ccaccatcaa gtccctgcgc agcgaactga
    11641 agggctcgta cgtcggcggg gacagcgccg agcagatcga cctggaggac accaacagcc
    11701 gggacacgaa ggtcgtcgtc cccctggtgc tcgtctcggt gctgctcatc ctgttcgtcc
    11761 tgctgcgcag tctcgtcgcg tcgctcatcc tggtggccgc cgtggtcgcg gtctggggcg
    11821 cggccctcgg gatcggcggg ctggtcttcg ggccggtcct cggcatcgag ggaaccgatc
    11881 cggggctcgg gctgctgtcc ttcgtgttcc tcgtcgccct cggcgtcgac tacggcatct
    11941 tcctcatgca ccgcatgcgg gaggagtgcc tggcgggcgc ggaaccggcc gacgccgcgc
    12001 tcaccgcgct gcggagcacg ggcgccgtca tcgcgtcggc cggcctggtc ctcgccgcga
    12061 ccttcgccgt gctgatgaac atggggctcg tgcaactcgt cgaactcggc ttcgtgatcg
    12121 ccgtcggcgt cctcctcgac accttcctcg tacggacgta cctggtgacc agtgccagcg
    12181 tcgccctgcg ccggaagatg tggtggccgg gcggcctctc ccgcgaaccc gcgcccggct
    12241 ccgggccgac cgaaccgacc gagccgccgc ggcagccgga gcaggtcggc gccccctgac
    12301 ctgcctggct caccccggcc gaccgggcgc ctctcccgcc atctgccgga gaggcgcccc
    12361 catgacggaa gatggagccg tgcaagatcg gggagcgacc tcagcttcag gggacctgag
    12421 aaccaccgtc gtacggggtg acgcgcggcc ccgccgcacc gaacgcgtca tggcggtcgt
    12481 caaccgggac ccgctcaccg cgccgcaccg cacccgcaac gacgcgttcc tcgccgtcgg
    12541 tgtagccgtg ctcgccctcg tgctcgcgtc gctcaccggc gacggacgac cgctcggccc
    12601 gcccggctgg gccctgctgg ccggcgccca tgtgccgctc gtgtggcggc gcagccgtcc
    12661 gctgctcgtg ctgctcgcgg tggcggcctg cgtcaccctg taccacgccc tcgactacaa
    12721 ccacgccgta ccgatccccg cgaccctcgt ggcgctctac acggtcgcgg cgaccggcac
    12781 ggtacgccgc tcgctgctca ccgccgtcgt cgtcctcggc ccgacgctga tcatcaacac
    12841 cttcaccaac cccgacgggg cactggagct cctgcggatc tccggctgga tcatcgcggt
    12901 cctgttcttc ggcgtcgacg cccgcttcta ccgccagtac gtcgcctcga tcgtcgagcg
    12961 ggccgagcgg gccgaacgga cccgcgagga ggaggcgcgg cgccgggtcg tcgaggagcg
    13021 gctgaggatc gcacgcgacc tgcacgacct gctcgcccac agcatcaccc tgatcggtgt
    13081 gcagacgtcc gtggcggccc acgtcctcac cgcggatccg gaccggctcg accgcacggc
    13141 ggtcgcccag gcgctcgacg gcatcgcgga cacctgccgg acggcccggg gcgagttgcg
    13201 tacgacgctg gaggtgctcc gggagaacga gacgggcgtg ggcttcgcaa gggaacggga
    13261 gcgggcggcc gcacccggct ccggatccag ttccggttcg gggctcggct cttcggacgg
    13321 gcgcgggccg ctgcccgggc tcgacgggct gggcgcgctc gcggaggcgg ccagggtggc
    13381 cggggccaag gtcgaactgt ccgtccacgc ggacggcgta ccgccctcgg tgggcgcggc
    13441 cgcctaccgg atcgtgcagg aggcgctcac caacgccgta cggcacgggg gccgcgacga
    13501 cctcaccgtc cgggtcggac tgaggacggc ggagaggacc ctgcgggtga ccgtcaccga
    13561 cgacggggcg gggcagggaa cgagccgggg ggcgggccag ggccacgcgg tgagcggggc
    13621 ggtgcgcaac ggggcggggc acgggcaggc ctccggcggc gcgccggggt tcgggctcgt
    13681 cgggatgcgt gagcgggccc gtagcgtggg cggcacactg gacgccggac cgggccccac
    13741 cgagggcttc cacgtgaccg ccgaactgcc gctgccccgg gaggagccct cgtgacggcc
    13801 ccgatgccca tccgggtact gctcgccgac gaccagaccc tcgtccgggc ctcgttcgcg
    13861 atgctcgtcg cgtccgccgg ggacatggag gtcgtcgccg aggcgggcac cgggcggcag
    13921 gccgtcgacc tcgcccgttc cgcgaaggcc gacctcgtcg tgatggacat ccgcatgccc
    13981 gacctggacg gcatcgaggc gacccggctc atcgccgccg acgagtacct ggcgggcgtg
    14041 aaggtgctcg tcctgacgac gtacgacacc gacgagcaca tcgtcgacgc gctgcgggcc
    14101 ggggcatccg gcttcctggt gaaggacatc cggccggccg aactcctcga agccatccgg
    14161 acggtggccg ccggtgactc cttgctgtcg ccgggaccca cctcacggct catcgcccgt
    14221 ttcctgcgcg cacccgacac ggcgatgtcg gcggtgggtg gcccgcacgg gctgtccgag
    14281 cgggagcggc aggtgctcac cctggtcgcg cgcgggttca acaacaccga gatcgccgag
    14341 gagttggggc tcagcccact caccgcgaag acccatgtca gccggatcat gggcaagctg
    14401 ggggcacgtg accgggccca gctggtgatc gtggcgtacg agtcgggcct cgtgataccc
    14461 ggggcggtct gagcaccgcc gccgagtccc ttcccctgga agctgtcggc ttcacacgct
    14521 gtttttcgac taggctccga aggcgcccgc ttttgtgaat ccgggcagtg gaacgagaaa
    14581 tatcgctttc gctgatcacg catggttggc cagtcgaatt ttcggatatc ggtccttgcc
    14641 ggcccgggca gcgcaatcag cacgtcggat tcccgcagga attccgtgcg gccgattacg
    14701 gcgcgcgggc agagcaccgg ggaagtccac aggcctcaca gtgatgacgc ggtgggcccc
    14761 agggcggaga cgaacttgcc cagccgggcg aggccctctc gcagttcgcc ggccgaggcc
    14821 gcgtacgaca gcctgacgtg gctctcggcc gtccccacgc cgaagtcccg gcccggggtg
    14881 agcgccacat gggcctcgct cagggcgcgg gcgcagaaat cccatgagct caggccggtg
    14941 gcggcgacgt cgaagtaggc gtagaaggcg ccgtccggcg gcaccggcac cggcagaccg
    15001 atccgctcca gaccgtccag gacgagcgcg cggcgctcgg cgaactccac ccggcgggcc
    15061 tcggccacgg ccagggactc gggggtgaag caggccaggg cggcgtgctg ggcgggggcg
    15121 gaggcgcaca ggaagtagtt ctgggcgagg cgttccagtg cgggcacgag ggcctcgggc
    15181 acgacgcacc agccgagccg ccagccggtc atgccgaagt acttggagaa gctgttgatg
    15241 accaccgcgt cggggtcgtg tgcgagggcg gtgcccggcg ggcggccgtg gtcgtcgggg
    15301 tctccgaggt cgaggtagat ctcgtcgacc agccgccatg ccgcgcgctc ccgggcgagg
    15361 gcgcacagcg tccgcagttc gtccgcgggg accgaggtgc ccgtcgggtt ggagggggag
    15421 gcgatcatga cgccgcgggt gtcgtccgtc cagtgcgcgc ctaccgactc cgcgtccagt
    15481 tggaagcggg aggccggggt ggtcgggacg agggtgacac gggcgccgaa actctccatg
    15541 atctgccggt tgcacgggta ggacgggtcc gcgatcagca cctcgtcgcc ggggtcgacc
    15601 agggcggcgg tggccagcac cagcgcggcg gaggcacccg cggtcaccgc gacccgggcc
    15661 ggatcgacct cgacgccgtg ccggtcggcg tagaagcggg cgatcgcctg ccgtagcgcg
    15721 ggcagtccga gagccgccgt gtacgccatg ggccggccgt ccatggcgtt gcgcatggcc
    15781 tccaggacgg cgggcggagc gccgaagtcc ggctcaccca ggctgagttt gacgacgtgg
    15841 tggcccgccg cctccagttc ggcggcctgc tttccgaact ccatggcgta gaagggagcg
    15901 atggcccggg cgcgctgcga gatcttcata ccgtcgattt tccggcatgc gggcggtcgg
    15961 ggcacaagtc agccgaagcg gtcctgccgc gtggtccgcc gtccgccggt cgggtcgtcg
    16021 cggggcctcg ggcggccagg tctttcgagc catccagcga cgacaggatc acagccgtac
    16081 cggaaccccg gacgcggcga tccttcaact caccgcctgg acccgcgccg ggaaggcagg
    16141 acaagcgcag gccgattcgg cgtaccgtca gccgggccct gccacggcag gggcgccggt
    16201 cgagcgcggc gtcacgctac tgagggcatg gcggatcttg cgaaaatccc ggagcaatcc
    16261 gaatcgaatg cagtcaatcg ccgcgcccct ccttaccctg gagcggcagg tctgaaacgg
    16321 ctcagtaaat gcatacggtc cttgccgcga gcgatcacat caagccatga cggcctcaac
    16381 ctccttgcag cgcttgcgga attgaaagtt taaatggaac ctgaaagcct gatcaccgac
    16441 gcggcagttg tatgtcctga tcgatgaggt gtccgtgcag gccaggaggg cgggtacggg
    16501 cacgggaacg gctgtcgtga tcatgaacgt gtctgacgac gatcaaggat caggtgggtg
    16561 gccgtcgagg ccacgacagc cgagcggacc tggacagcgg tgtccgggtc gccgatggcg
    16621 gcgacggccg tctgcttccc gcagccgggg acgcgtcgat gtcggtgccg gccgcccggg
    16681 actcgcggat gctgggcagg acgatgacac gggggatact gatggggttg gagcggtgtg
    16741 actgctgggc actcccagag gctctgggcc gtgacgggcc gtacgggctg aagcacttgc
    16801 tctcgcgcgg tgcccgcagt catgacctgg cccgcgatca tgccgccgcc cggacggcag
    16861 gcaactcgcc gacgacgagg ccgcgccggt cgtccacggg gcgggcgatg aggggttctg
    16921 ccagcggcag ccgcatccgg ccgccgcgat gttgcaccgt gaccgtgaac tggggcttgc
    16981 caaaagctgg ttcaccggcg acgaggtctg tggcactctg gagttgcgcc gcaccgccca
    17041 caccctgggc ttcgactgcg ccctggctgt caaggccgac caccgcgcca ccgccgccgt
    17101 cggccgtcgc gcggccacac agccggccgc gaaggtctcg gccaggacct ggatgtgctt
    17161 gcgcataggc cacggcacca agagcgatcg gtactacgac cgggcattga tcgacgtcct
    17221 gcctcgcgac acaccgccgg gcaggggtgc gcgcaccacc ggccgccctt cctccttctg
    17281 ggccttcggc gtgcgccgga accgatcagt ctgttcgctg ccgctctcct cggcgtcacc
    17341 cacgcccgca cccgcaccac cgacggagcc gggcgcgtcc tggaacgcgc cccggccact
    17401 ggcctcgtgt tcctggccgt cctgagagcc tctggccaac ctgaggatca ccgcattccg
    17461 cacccccgat gcgaccgggg ccgcactctg caccggtccg cctggcgccg ccatcaacag
    17521 caccaggcca ccgaggctct ccgccggtgg aacgacatca ccgccgcggc ggccgcgtgg
    17581 cccgagcccg tggatcaaga cgtacagctg ccgtgaccga agggacgggg aggatttcac
    17641 atgccgcaaa cgtcatttct ggcggattct gcgcgcacat tttccgacgc tgggacatgc
    17701 gtcaaatgtc agctcatccg gcaggcgata gctctctgga tgaatggctg gtcggatcgc
    17761 agtctgcatc tcgccgagga atcagccgcc atgacggccg gcgactcatc atgcgaatgt
    17821 gacctgcatg ctgtgatgtg gttggccttc gtgctgacca cgagaggtga atccgatcgc
    17881 gtaaggaaac ttctccacca tgcggagagc ggggacagca gtctcttcgg cccggtgatg
    17941 gtgccggccg gactctcgct ggcccggtcg cacctggctt tcatggccgg agatctggac
    18001 gtggcggcgg ccctgagtga gcaggtgctt gcgcaggccg aaggcagccg ggaaatccgt
    18061 atcgcgagtc atctcatcct ggcattgatc gctctgcggc gtgcggaagt gaatgcggct
    18121 tcgtcgcaca tgcagatgat atccgacgac gcattcatgg ggcgtctcac cgtgttggcg
    18181 gggccgtgcg catgggtgaa cgtgcggatg cgcgaggccc aatggggagc cgagggcgtc
    18241 gcgccggtca tcgaggagct cgtcgacttc ggcccggtca gcaggaagat attcctgtcg
    18301 cagtcggctg ccgccccctg gatcgtgcgg ctggcgctga aattcgacca gaaggcgacg
    18361 gcgcacaaag cggtcaagct ggctcagaag ctggctgaaa ggaacccgca gcatcatgtg
    18421 ttggccgcat cggccctcca cgcccaaagt ctgttcgagc gaaatctggt cggtctgcgg
    18481 ctcgctgcga agatgcatgt ccacccctgg gcgcgagctt cgactacgga agacatcgga
    18541 aagttcttgg cccatgagcg gtcgcaacag gaccaggcca taggaatatt cgagcagagc
    18601 gctgacgcct atatcaaggt gggagccccg cgcgatgctt tgcggatcaa gaagaggctg
    18661 tgggatctcg gtgtcaggca ccatcaatcc cgctggcgcg caactccacc ggcggcgatc
    18721 gggaatctca ccgaaacaga agccaaggtg gcgcaactgg tggcacaagg aatgaccaac
    18781 acgcagacgg ccaagaacct tttcatatct cctcacacgg tggcctacca tctgaagaaa
    18841 atcttctgca agttgcagat ctcctcacgt gtggaactgg ccagggactg gaccactatc
    18901 gagggtcccc agggtggccc ccggacggct gacggcggga ccgcaggcaa cggacggggc
    18961 tcccgtgccg tcgagagagg tctctgaccg ctgacgcgac cagcgccgaa cggccttcgg
    19021 tccggagcta ccagaccagg ggatgcctcg cgaagcccgc actgtctagt gtcgtgcggg
    19081 tcagctctcg atcttcgcgg accgactgcg gtcttgacga actgcccagc agatccaggg
    19141 gtctttgtgt cttctcttct tcacatcgat gcgagcatcc gccatgaggg atccacgtcg
    19201 cgtcagctga cctcgtactt cgtgacccgg tggcggcaga accaccctga cggcggctac
    19261 gtctaccgcg acctggctgc cgagcccatc ccgcacctca cccatcccgt gcgcgaatac
    19321 ctcctggacc ccagccgcga tcacggtcag acggacgagg agaaggcgct cgtccacacg
    19381 gtggcctccg aggtggccga cgccgacacg atcctgctcg gcgtgccgat gtacaactac
    19441 acgatcccgt cacacgtcaa agcctggatc gacctgctgg tcagcccggc ccacatggtc
    19501 ctcccggggg ccgattccgg tccgctcagc ggcaagtcgg tcatcgtggt gaccgcgcgc
    19561 ggcggctcct acgcaccggg caccccccgc gagggccagg accaccagga gccctacctg
    19621 cgggacgtcc tcaaggcgat cggtctcgcg gacaacctca ccttcgtcaa cgccgaactg
    19681 accctggccg cgaccgtgcc ggccctggcg gaactcaagc cgctggggga gaagtccctg
    19741 gcgactgccc aggagacgct caggaagctc gccgcctgat gcccgcacgc ccgcagatct
    19801 cctaggagtc cgtacccgct tgccgccgcc cgctggagac cgcgggcggg cggaagcgcg
    19861 tcaccgggcc ggccgaggac acaggctccc tgcgggtgca gcaggtcgcg agcaggtcgc
    19921 cacaccgcac agcacagacc tacccgcttg cctgacagca gttggccgtc accgatagcc
    19981 ggttaggagt tcgagccgag gtgcttcccg acctgatcac cccgctaccg gtcatcctga
    20041 gtgagaacgc gggccggttc ccggacaaga tcgccttcga ggacgaccgg tacgcggtca
    20101 cctaccggga actcgacgca cggacgagga gactggccgg tcacctggtc ggcctcggtg
    20161 tccggcgcgg cgaccgggtg gccctgtgtc tcggcaactc ggtcgcgatg gtggagagtt
    20221 acctcgccgt ggtacgggcc ggcggcatcg gcgtgccggt caacccgcag gccgccccgg
    20281 cggagatcgc atatctcttg gcggacagcg aggcgacgct cgccctcacc ggcacggcac
    20341 acgcggagac tttcgttcag tcgcttcccc gcgtcacccg gcgggtgtcc gtcgtcgtgg
    20401 caggcgcccc cgacgccggg cgcctgctgc ccccgggcac cgtaccgttc gaggaactcg
    20461 ccaccaccga gcccgccgac gaacccccgg acgacctcgc tctcgacgag gtggcctgga
    20521 tgttctacac ctcgggcacc accggccgcc ccaagggcgt cctctccacc cagcgcaact
    20581 gcctgttctc cgtcgcctct tgctacattc ccgtgcccgg cctgtccgag cacgaccgcg
    20641 tactgtggcc attgccgctc ttccacagcc tgtcccacat tgcctgcgtc ctgtccgtca
    20701 ccgtctccgg cgccaccgcc cggatcatgg acggcagttc ggccgacgac attctgaccg
    20761 ccctgcgcga ggaccggtcc accttcctgg ccggcgtccc caccacctac caccacctgg
    20821 tcgacagggc ccgccgcacc ggcctctccc tgcccgatct cagggtcggt ctcgtcggcg
    20881 gcgccgtcac cggccctgga ctgcgccgct ccttcgagga gaccttcggc atccccctcg
    20941 tcgacgccta cggcagcacc gagacctgcg gggccatcac cgtcaacccg cccgacggcc
    21001 ccgtggtcga gggctcctgc ggccttcccg tgcccggtgt cggagtccgg atcgtcgacc
    21061 cccgcaccgg gcaggacgtg cccgccggac acgagggcga ggtgtgggtc agcgggccga
    21121 acgtcatggt gggctaccac aacaacccgc agggcaccgc cgaggcccta caggacggct
    21181 ggttccgcac cggcgacctg gcccggcgcg acgaagccgg ctacttcacc atcagcggcc
    21241 gcctcaagga cgtcatcatc cgcggcggtg agaacatcca ccccgacgag atcgaggccg
    21301 cactgcgtgt ggccgagggc gtggccgacg tcgcggtcac cggcatggcc cacgacaccc
    21361 tcggcgaggt gcccgtcgcc tgggtggtcc ccggtccggc gggcgtcgac ctcgcccggc
    21421 tgctcgaccg gtgccgtgcc caactctccg cgtacaagct ccccgagcgc gtgtacgagg
    21481 cccgggccat ccccaggacc gcctcgggga aggtcgtccg gcgtctcctc cccgacctgc
    21541 cggcccggct gcggtacgcc gccgacggtc accacgaggg actgatgctg agggactgga
    21601 gcaaggtggc ggtctcctct gacgcgccgg aagggctgcg ctgggcagtg gtcggccgga
    21661 ccgcagccac cgacggcctg gtcgccgccc ttcggaaggc cggtgtcgcc gacgtacggc
    21721 actacgcaga cctttccgcg tcacgcacca cccctgacgc ggccgccgac gtgacggtcc
    21781 tcgcagaggc agaggcagag gcagaggcag acgcggacac atgggcgccg gcccgcgagg
    21841 gggtgggtcg ggagaccggg tcccggctcg tcgtcctcac ccggggcgcg atgggcgtca
    21901 ccgaccggga cgggacgccg gacggcgccg aagtcgccct gtgggcagcc gcacgggccg
    21961 cacaggccga tccgggtgac ggcgcgccgc tgacgatcgt cgacgtcgaa gccggcaccc
    22021 cggggtccga gtgcgccgtg gcgctgatca ccgccgtctc ctccggtctg ccccaactcg
    22081 ctgtacgcga cggggagctg atgcggccca ggctcgtgcg cctccccgtc gccgaccggc
    22141 cggatcctgc catgccgggg atcgaaggcg tcgtggtcgt cacaggcgcc gacaccagga
    22201 ccggctcggt cctcgcccgc cacctggtca ccgggcacgg aacacgacac ctcgtgctcg
    22261 tccaggcgac gcataccaac gaccggtgga gccaggacga gccgctgccg cagggggtgg
    22321 acatcgtccg cgtcgtggcc gacggctcgg acacgctgga gttgtacgag gccctgaccc
    22381 ggaccggtcc ggtgaccgcg gtcgtccaca ccgccgatga tcccgaactc gcccgagcac
    22441 tgcacgactt caccgcggac gacgatgtcg ccgcgttcgt cgtggtgacc gacgccgccg
    22501 cactggtggg cgcttcggag tccgacggcc tcgcctcgac ggtggtcacc gccgccctca
    22561 ccgaggccgt ggtccgcgac cggcgactgc acggactgcc cggctcgctg ctggccctcg
    22621 gccggccgga cgagggcccc gccgctttcg acgcactgat cgagaccgga tccccggccc
    22681 tgctggcgct ttcgccgagc accatcaacc ccggcgaccg ggtgcggacg ctgctcggca
    22741 ccctgacgga tcaggagccc cgcgccaccg ctcgggccga cgagacgatc accgccgccc
    22801 tgcgcgcgcg tctggccgac ctggacgagc ggggccagct cgccctgctc ggcgagatga
    22861 tccgcaacga gaccgccgcc gtccgaaccc acgcgagccc cgaaccgatt ccggcgggcc
    22921 ggtccttccg cgacctcggc ctcggctccc tcgcggtcgt cgagctgcgc aaccggctga
    22981 ccggacggac cgggctgcgt ctgcccacca ccgtgacctt cgaccacccg actcccgagg
    23041 ccctcgccgc gcaccttcgg gccaggatcc tgggtctgca cgacccggcc ggggaggcga
    23101 cggcggacag ggaccggacc ggggccgccg gccctgcgga gccgatagcg atcgtgggta
    23161 tggcgtgccg ccttccaggc ggtgtggcga gcccccagga cctgtggcgg ctggtcagcg
    23221 agggccggga cggtgtgtcc ggcttcccgg aggaccgagg ctgggatctg gacggcctgt
    23281 tcgatgccga cccggagaag accggcacgt cgtatgtcga tcagggcggc ttcctgcacg
    23341 aggcgggcct gttcgacgcc gggttcttcg ggatctcacc gcgtgaggca cttgccatgg
    23401 atccgcagca acgactgctg ctggagacct cgtgggaggc gctggagcgg gccgggttcg
    23461 acccggggac gctgaaaggc cgtgacgtcg gcatcttttc cggcctgatg ggacaagggt
    23521 acgggctctc gggtgcggct ccggctgagc tcgagggctt cggcgagacg ggcaaggcgt
    23581 cgagcgtggc atccggacgc gtgtcgtacg tgttcggttt cgagggcccc gcgatcaccg
    23641 tggacacggc ctgctcatcc tctctcgtgg ccatgcacct ggcggtccag tcgctgcgcc
    23701 agggcgagtg ctccatggcg ctggcaggcg gcgcgacggt gatggcggag ccgtccacgt
    23761 tcgtggggtt ctcgcggcaa cgtgccctgt cctcggacgg ccgctgcaag tcctacgcgg
    23821 atgccgcgga cggtacgggc tgggccgagg gcgccggtgt cgtcgtcctg gagcggctct
    23881 cggaggcgcg gcgcaacggg caccggatcc ttgcggtgat ccgtggcagc gcggtgaatc
    23941 aggacggcgc gtcgaacggt ctgacggcgc cgaacggtct tgcgcagcag cgggtgatcc
    24001 gtcaggcgtt ggcggcggcc ggtctctcgg cggctgaggt cgacgtagtg gaagggcacg
    24061 gcacgggcac ggtcctcggc gatcccatcg aggcgcaggc cctgctggcg acgtacggca
    24121 gtgaccggga acccgggagc ccgttgtggc tggggtcgtt gaagtcgaac atcggtcaca
    24181 cgcaggcggc ggcgggtgtg gccggtgtga tcaagatggt gcaggcgctg cggtacgggg
    24241 tcatgccgcc cacgctgcat gtcgatgctc cctcgtcgaa ggtggactgg tcggcgggtg
    24301 ccgtccaggt gctgaccgag gcccgcgcgt ggccggagac cgggcggctc cgccgtgccg
    24361 gtgtgtcgtc cttcggcctc agcgggacga acgcgcacct gatcctggag caggccccgg
    24421 agacggagcc cgtcgacgcg cggcccgtcg agtccgagcc gacggcagaa gtcgtcgacg
    24481 gcgtggtgcc attggtcctg tccgccgcct ccgcggcatc cctcgtgggg caggccgagc
    24541 ggttggcgtc ctttgcggag tcgactgagg tgtcactgcc gcatgtggcg ggtgcgttgg
    24601 tcgctcagcg tgcggtgttg tccgagcgtg cggtggtggt ggccgagccc ggggtggagg
    24661 cgttggcggg gcttggtgcg ctggcgcggg gtgagtcgaa gcccggtgtg gtcacgggca
    24721 gcgcggtggg tgcgggtagg acggttgtgg tgtttccggg tcagggttcg cagtgggtgg
    24781 ggatgggacg tgaactcctc gactcttcga cggtgtttgc ggagcgggtg ggggagtgtg
    24841 cggcggcgtt ggagcggtgg gtggactg
//
