LOCUS       NZ_BMSI01000009        27582 bp    DNA     linear   CON 02-AUG-2024
DEFINITION  Streptomyces asoensis strain JCM 4185 sequence09, whole genome
            shotgun sequence.
ACCESSION   NZ_BMSI01000009
VERSION     NZ_BMSI01000009.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces asoensis
  ORGANISM  Streptomyces asoensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 369621)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014649075.1-RS_2024_08_02
            Annotation Date                   :: 08/02/2024 04:45:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,813
            CDSs (total)                      :: 7,736
            Genes (coding)                    :: 7,563
            CDSs (with protein)               :: 7,563
            Genes (RNA)                       :: 77
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 53 of 173
            Pseudo Genes (incomplete)         :: 140 of 173
            Pseudo Genes (internal stop)      :: 10 of 173
            Pseudo Genes (multiple problems)  :: 28 of 173
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:21:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 326506
            Orig. end                         :: 354088
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMSI01000009.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..27582
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /product="lanthipeptide-class-iii"
                     /region_number="2"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..27582
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="neighbouring"
                     /product="RiPP-like"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..10216
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10216
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5216](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5216)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            complement(1889..4111)
                     /locus_tag="IE189_RS23175"
                     /old_locus_tag="GCM10010496_47200"
     CDS             complement(1889..4111)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978106.1"
                     /locus_tag="IE189_RS23175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_47200"
                     /product="NHLP family bacteriocin export ABC transporter
                     peptidase/permease/ATPase subunit"
                     /protein_id="WP_189924536.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 2e-37, bitscore:
                     122.3, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATRETRGRRRAAPPRRTVPKSRTKTVRTPTVLQMEAVECGAAS
                     LAMVLGHYGRHVPLEELRIACGVSRDGSRASNLLKAARGYGLTAKGMQMDLAALAGVRS
                     PAILFWEFNHYVVYEGLGRRFGRRGVYINDPGKGRRFVPMEDFDGSFTGVVLVLEPGED
                     FERGGRRPGVLGAMPARLRGTAGTLPAAVLASLLLVLVGSAVPALSRTYIDMFLIGRQT
                     SLLGVLFASMATCVALTVVLTWLQQANLHHGRIISSTLSSARFLRHLLRLPVTFFSQRS
                     PADLVQRLQSNDAVAETLARDLASAGVDAVVVVLYAVLLYTYDPQLTFVGIGVALLNIV
                     AMRIVVRLRATRTAKLRADNARLTNTAYTGLQLIETMKATGGEDGYFRKWAGQHATTLE
                     EQQRLGVPSAWLGVVAPTLATFNSALILWIGGMRAIEGHISVGLLVAFQALVARFTAPL
                     TRLNGVAGRIQDFAADVARLKDVENFRADPLYDRRFGGDSTRRLHGHVELENITFGYSP
                     LDQPLLSGFDLTVGPGQQVALVGGSGSGKSTVSRLISGLYTPWEGVIRVDGQRLEDISR
                     GALASSVSFVDQEVFLFEGSVRDNVALWDPSIPDDAVVEALRDAALYDTVARRPGGIHG
                     RVEQDGRNFSGGQRQRLEIARALVRRPSILVLDEVTSALDAETEQVVMDNLRRRGCACV
                     VIAHRLSTVRDSDEIVVLEHGSVVERGRHEELVARGGAYAALVRER"
     gene            complement(4108..4914)
                     /locus_tag="IE189_RS23180"
                     /old_locus_tag="GCM10010496_47210"
     CDS             complement(4108..4914)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386622.1"
                     /locus_tag="IE189_RS23180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_47210"
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="WP_189924538.1"
                     /transl_table=11
                     /translation="MQFRQQALAKLQSPEELDLPVRFARPQGWLVLSVTIVVMAAASVW
                     AVTGSVSSTVSAPAVLTHGEGSYILQSPAAGQVTAVLAKEGERLPAGSPVLKVRTERGD
                     TVVRTVAAGRISALAATIGQIVSTGANVAAVEKVAHADDPLYATVYVPAENGASVPEGA
                     AVDLTVQTVPSQEYGVLRGHVKSVDRAAQSAQAIAAFLGDSRLGEQFTEDGRPVAVLVR
                     LDRSATTKSGYAWSTADGPPYPLTSMTMGTGSIRLADQRPVDWLLP"
     cand_cluster    4901..27582
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    4901..27582
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[14900:17582](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(14901..17582)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="2"
     misc_feature    complement(4981..5001)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.89"
                     /tool="antismash"
     gene            complement(5001..5216)
                     /locus_tag="IE189_RS23185"
                     /old_locus_tag="GCM10010496_47220"
     CDS             complement(5001..5216)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: strepbact"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020128984.1"
                     /locus_tag="IE189_RS23185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_47220"
                     /product="type A2 lantipeptide"
                     /protein_id="WP_189924540.1"
                     /sec_met_domain="strepbact (E-value: 2.3e-38, bitscore:
                     125.0, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSTPQVQTAEISDAELDNVAGGLSLNAVGTVTGLVDGVAPVSGL
                     VNTVVGTVEGVTGLNTAPVTNLVAGL"
     misc_feature    6237..6246
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.44"
                     /tool="antismash"
     misc_feature    6240..6253
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.24"
                     /tool="antismash"
     gene            6243..7772
                     /locus_tag="IE189_RS23190"
                     /old_locus_tag="GCM10010496_47230"
     CDS             6243..7772
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020134775.1"
                     /locus_tag="IE189_RS23190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_47230"
                     /product="S1 family peptidase"
                     /protein_id="WP_189924542.1"
                     /transl_table=11
                     /translation="MSHKRVTKRKAIIAAGGVAALGAAAILLPQANASQDGTSDGAASV
                     KTLKAGDASDLASQLEKLLGDAFAGSYYDDAGKQLVVNVVNVSGDKNNVVVQAEKAGAK
                     VREVENSKAELEAAAKTLKAKATVPGTSWAVDPKTNKILVTADSTVTGNKWDQVDSTVK
                     TLGSGMATIRKSAGTLKPLVSGGDAIFGGGARCSLGFNVTAGDGSPAFLTAGHCGVAAE
                     QWSDSQNGQPIATVDQATFPGDGDFALVKYDDPNTQAPSEVNTGQQTVAISQAAEATVG
                     TQVFRMGSTTGLNDGQVLGLDATVNYPEGTVTGLIQTDVCAEPGDSGGSLFTQDGQAIG
                     LTSGGSGDCTVGGETFFQPVTTALAAVGATLGDGGAGAGDAAGGAGAGAGAVDENGDGI
                     DDNTGEAIQGGGDAGAGAVDENGDGIDDNTGEAIQGGGDAGAGAVDENGDGIDDNTGEA
                     IQGGGDAAADGGADQNANGGADASGDGQDQSGNGKNRKGGQQDGSGVNESH"
     misc_feature    6247..6262
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 18.42"
                     /tool="antismash"
     misc_feature    complement(6247..6264)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.85"
                     /tool="antismash"
     gene            complement(7846..9999)
                     /locus_tag="IE189_RS23195"
                     /old_locus_tag="GCM10010496_47240"
     CDS             complement(7846..9999)
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020117170.1"
                     /locus_tag="IE189_RS23195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_47240"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_189924544.1"
                     /transl_table=11
                     /translation="MVAVSDGQTSSGQAPAPVWTPVDRPLLSLALTSMMDAVGAHSGAV
                     YLRPGDGPVLEMAVMAGLPRSFAAPWERVGVSAPIPVAEAVRERRLVWVGGAEEMARRY
                     PRIAVVLPYPFALAALPVLGPSRVHGAVYVTWPGSHPPELSDRERRELTTACERLALRL
                     ERAASENRSVRAESDLLDLSVSGVSDTLGPLEAARMVARLPYGMCSLDVSGRITFANEA
                     AAELLGVPVGELLGSQLWAAVAWLNDPLYEERYRAALLSQEATSFVALRPPSHWLSLRL
                     YPSTTGISVRISRARAVSETRPSDARAEDAPTRLVSMSQALSLAGALTETVSVQDVVGL
                     VADEIAPAVGSQALALLGARAGRLHVLGHHGYPEPRLVERFDRTPLSSPTPGAHAVTHG
                     VPAFFESRQHLERLYPARRSSPDGFAAWAFLPLIASGRPVGACVLAYAEPHVFSTHERA
                     VLTSLAGLIAQALDRALLYDVKHRLAHGLQAALLPPSLPSLAGIEATARYLPATRGMEI
                     GGDFYDLVPSAPLAAAVIGDVQGHNVTAAGLMGQIRTAVRAYTTVGQEPGEVMRSTNRL
                     LIDLGSELFASCLYLRLDPAAGRAVMARAGHPPPLLRRADGRVRVLDLAGGPLLGIDGA
                     AAYPTTEVELTTGCVLALYTDGLIETPGVDIEDAVAELGRRLGEAGNRPLEEVADDLVG
                     RHATAEERLDDVALLLLRAVADG"
     gene            10290..10898
                     /locus_tag="IE189_RS23200"
     CDS             10290..10898
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010354522.1"
                     /locus_tag="IE189_RS23200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_189924546.1"
                     /transl_table=11
                     /translation="MIQVLLVHDACLVRSVLAQWLSREPDLRVDDVPWRGAAGRVGAVR
                     PDVCAADLDCSEASGLPPLGELCPRGGGLVPPRLLVLASAHRPGLLKRALEAGALGYVD
                     KEGTPEQLVSGIRKVARGERFVNSSLGFGFLKAAEMPLTRRELSVLTLAAEGASVAEIA
                     GNLHLSHGTVRNYMAAITRKTGARNRVDAIRISQGQGWL"
     misc_feature    10488..10490
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(<11160..12365)
                     /locus_tag="IE189_RS39180"
                     /pseudo=""
     CDS             complement(<11160..12365)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="IE189_RS39180"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="ATP-binding cassette domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVSRSFVFTCVGALAGLASLAPPLLLVVAPPLAAGVGLFFVTLRP
                     LARRQERFLAADEALAQDLGVVCPGLRDVTAAGAEDRIARDTGALVEAESQAARVLARW
                     GVARVVCLALGGRLPLVLLLAGGPWLLDHGVSPGALVGALAYVTQSLVPALTALVHGLG
                     TSGSRLTVVLRRLTDSGAGPGPRSRADERAVCGPRPPSPHRAGGAPRAGASKADAPKAE
                     AARAAVSWVPPLAGASGSVPSALTLSSLTFAYGAAAAPVVDGLTLDLPAGAHLAVVGPS
                     GIGKSTLTALVAGLLEPVRGEIRICGRPVPGADAAARRVLIPQEAYVFTGTLGENLTHL
                     REDAVPEDELLAAADAVGLLPLLDRLGGPAAPVEPAALSAGERQLIALTRAYLSSAPLA
                     LLD"
     gene            complement(12761..14575)
                     /locus_tag="IE189_RS23210"
                     /old_locus_tag="GCM10010496_47260"
     CDS             complement(12761..14575)
                     /EC_number="7.-.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020128988.1"
                     /locus_tag="IE189_RS23210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_47260"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_229901381.1"
                     /transl_table=11
                     /translation="MDRTTGELLGSATRHGGPRPAALALLGVTATGASLLLPAALGRAL
                     DLLLAGGGATPWVLCCAGLALLLTLLDAGETVLTGTLDAKTTAFLRHRALGHVLALGPR
                     ATARFEAGDLVARVVGGAAQAGAAPGARAALPAALAGPVGAVAALALIDPWLAAVLLTG
                     APVLTLLLRSLARDTSSCVAAYLDAQGRIAAALTEAVGGARTIRAAGTAARDTARVLRP
                     LPELSRAGRRMWQVQGRAAAQATAVAPLLHIGVVAVAGLLLARHRVSPGDVLAASRYAV
                     LATGVGVLVGQLSGLARSRAAAARLGEVLNAPAPSYGTRGLPADGPGRLELRGVSARRG
                     DRAVLDGLDLVVPGGTALAVVGRSGAGKSLLAALAGRLTDPDAGEVLLDGVPLAALRRS
                     ELRAAIAQAFDRPALLGATIEDTVSLGSASPARVREAARAARADDFVRRLPDGYATRCA
                     DAPHSGGEAQRLGLARAFAHGGRLMILDDALSSLDTVTERQVTQAVFGRTTTATRLVVA
                     HRASTAARADAVAWLDGGRVRAVGTHAQLWRTAAYRKVFATDTENGTGPGSAPPADTQA
                     EAQAEADAQAEARANARAEDGCGPVTRR"
     gene            complement(14725..14841)
                     /locus_tag="IE189_RS23215"
                     /old_locus_tag="GCM10010496_47270"
     CDS             complement(14725..14841)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019983510.1"
                     /locus_tag="IE189_RS23215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_47270"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_189924634.1"
                     /transl_table=11
                     /translation="MALLDLQTMESDEHTGGGGNSTVSLLSCVSATSVLLCL"
     CDS_motif       complement(14782..14841)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MALLDLQTMESDEHTGGGGN"
                     /locus_tag="IE189_RS23215_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(14725..14781)
                     /prepeptide="core"
                     /locus_tag="IE189_RS23215_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="24.00"
                     /molecular_weight="1670.0"
                     /monoisotopic_mass="1668.9"
                     /core_sequence="STVSLLSCVSATSVLLCL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MALLDLQTMESDEHTGGGGN"
                     /leader_location="[14781:14841](-)"
                     /alternative_weights="1688.0"
                     /alternative_weights="1706.1"
                     /alternative_weights="1724.1"
                     /alternative_weights="1742.1"
                     /alternative_weights="1760.1"
     gene            complement(14901..17582)
                     /gene="lanKC"
                     /locus_tag="IE189_RS23220"
                     /old_locus_tag="GCM10010496_47280"
     CDS             complement(14901..17582)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020117174.1"
                     /locus_tag="IE189_RS23220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_47280"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_189924550.1"
                     /sec_met_domain="micKC (E-value: 6.1e-227, bitscore: 749.9,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 3.1e-10, bitscore: 34.2,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.1e-06, bitscore:
                     22.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKRYEVYALADAHFYETPDRLTGDGPAPLFDTALRPVPSGWTSA
                     RTGDWLALTPLAADGSPVAGPAQGWKIHASATRANADDVARIVWDYCVPRRIPFKFVPG
                     PHLLHLRNTKYAGRDTSGKFVTVYPGDEERLHTVLRELGALLEGFEGPYILTDLRWGEG
                     PLYVRYGAFARRYVVDDRGSLVLAVLDGEGTLVPDRRAPSFQVPEWVTLPPFLEPHLAA
                     RNTTTVGELPYRIEKALHFSNGGGVYAGTDTRDGRKVVLKEGRPHAGLAADGADAITRL
                     EREKHALEAVAGTGVVPEVRDWFTLGDHRFLVMDLVEGRPLNAFFAERHPLLCPDPDPG
                     AVAAYTRWAVRVHRSVERAVEKVHARGIVFNDLHVFNIMVAPDDESVFLIDFEAAAPIG
                     ENGRQIVAHPGFFAPPDRRGADVDRYALACLRLALFLPVTTLFVVDRGKAAHLAEVIAE
                     QFPDVPREFLDAAVAEITRDIPSGAPATGGSGPAAPPRSAVRLPAAPAFRVEPGDWPHS
                     RDSMVKAILASATPERDDRLFPGDVAQFSDGGGLGLAHGAAGVLYALRATGAERFDDGE
                     RWLLDRTAPAPTGTPLGLYDGLAGVAHVLELLGHRGRALDLVDGILRERWQNLSSDLHG
                     GLAGLGLVLGDLARRTGEPELRERAAEAADIVVRRLGEPVPGTARRQRAGLLRGASGPA
                     LFLLRQYEETGERRLLEAAGVALHRDLAACVEREGGAVEVDEGWRTLPYLGDGSVGVGL
                     VLDDHAVHVPYGEPEFERSRAGIRTAATSRFYAQPGLFQGRAGMILHLARTTAPDAPRA
                     RLDGQIAALGWFSMPYQGQLAFPGHQMMRLSMDLGTGTAGCLLALAAALDPDGTGADAH
                     LPFLPPPHRRPSDAAPRQPTES"
     misc_feature    17615..17631
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 19.82"
                     /tool="antismash"
     gene            17795..20254
                     /locus_tag="IE189_RS23225"
                     /old_locus_tag="GCM10010496_47290"
     CDS             17795..20254
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003995665.1"
                     /locus_tag="IE189_RS23225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_47290"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_189924552.1"
                     /transl_table=11
                     /translation="MADVVSEGAAERRTGPPRAEIALEAIRADPAAPDRVRRTLEQALV
                     FAGAALAALYTPAQGRLLRLVDSAGAPRTLYGLREDYPLDGDSPVAAALRADRPVWLGP
                     EDLAGAADHPPAQRTPAGAVHLAVLPVRDGRGGCLLAVREHPGGFGPDDRACLRLVADA
                     VALLAPAVTAEDGRPHPDAFSLAMDTGRVEVGDEILDLFGMGRADFDGRVETLLGLTVP
                     EDLPSLMSVVEADHMSIGDRELEFRVLQPTGPPRWLRLRGRLLPGGADRAARLVGTVTD
                     ASSLRDEVTDVSRVQRLATALATARTVGDVSQAVVAALRKPLRADRIALAELENDRLVV
                     TVLDPPEPDAWPELWQLEWRAEWPDAPVRAMPTLAAALREGRARIWPAGTALEPALAEV
                     GPGGLGVLPLSAGGRTAGVCLIGWDEPHEFRPDERALLTAFAGLAGQALTRARAFDAEH
                     ELVGMLQRQLLPRRLPELPGGVAVARYLPATAGLEVGGDWYDVIPLPDHHVALVIGDVQ
                     GHSAAAATLMGQMRTALRAYAAEGHPPDVVVSHANRLLMELETDLFVTCCYVDVDMEEG
                     TAWCVRAGHPPPVLRHPDGSTEIAEADGGPPLGVVTRAEFPMTPLRLVPGAVVVLTTDG
                     LVESAGLDIDTGLDRLARAASAADPAHLGLVADTLLGGAHRGDDVALLLMRYDGMAVKP
                     LREGWTVWRVPEAARQARRFTRRTLRAWGVSAHTLDAALLVVSELVTNALVHTDGRVRL
                     DLTLVNHRLRVAVTDTSPRSPVKPASLGWEATGGRGILLVEAVSQAWGTVPVSGGKQVW
                     SELTPTG"
     gene            20305..20646
                     /locus_tag="IE189_RS23230"
                     /old_locus_tag="GCM10010496_47300"
     CDS             20305..20646
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020128992.1"
                     /locus_tag="IE189_RS23230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_47300"
                     /product="DUF6479 family protein"
                     /protein_id="WP_189924554.1"
                     /transl_table=11
                     /translation="MDTFASVFVAASGRSALATVAFIAVGLVLVGGLIWAFRLGFKVRS
                     REPAPPAPHEQPRRPGTAPAHETHRTREPNAMPEPTDGERLTPHQLRPTGSRDSADQRR
                     PRWEEGSGG"
     misc_feature    complement(20698..20712)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     gene            20721..20906
                     /locus_tag="IE189_RS23235"
                     /old_locus_tag="GCM10010496_47310"
     CDS             20721..20906
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020128993.1"
                     /locus_tag="IE189_RS23235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_47310"
                     /product="hypothetical protein"
                     /protein_id="WP_189924556.1"
                     /transl_table=11
                     /translation="MTAHTEEQPVILRAETGWARARRIRRQSTALRTCLPAVAAAPSAT
                     AGMQTGAEWNIVRGED"
     misc_feature    20965..20978
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
     gene            20974..22041
                     /locus_tag="IE189_RS23240"
                     /old_locus_tag="GCM10010496_47320"
     CDS             20974..22041
                     /EC_number="2.7.7.24"
                     /GO_function="GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015655801.1"
                     /locus_tag="IE189_RS23240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_47320"
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="WP_189924558.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 5.9e-10, bitscore:
                     34.0, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKALVLSGGAGTRLRPITHTSAKQLVPVANKAVLFYGLESIAAAG
                     VTEVGVIVGDTAAEIREAVGDGSRFGLDVTYIPQDRPLGLAHAVIVARDFLGDDDFVMY
                     LGDNFIVGGITDLVDEFRRTRPDAQILLTRVRDPRAFGVAELDPAGQVVGLEEKPAHPR
                     SDLALVGVYLFTPAIHDAVRAVRPSGRGELEITDALQQLIDTGARVRSTIIKGYWKDTG
                     NVVDMLEVNRTVLEGVERRIEGEVDDSSETVGRVVVEAGARVVNSRLVGPVLLGAGSEV
                     RDSYIGPFTSVGENCRITDSELEFSIVLRDSSIEGVGRIENSLIGRHVEVTPATGVSSA
                     HRLVLGDHSKVQIHP"
     gene            22038..23006
                     /gene="rfbB"
                     /locus_tag="IE189_RS23245"
                     /old_locus_tag="GCM10010496_47330"
     CDS             22038..23006
                     /EC_number="4.2.1.46"
                     /GO_function="GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA]"
                     /GO_process="GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (4-174). E-value: 2.7e-19.
                     Score: 61.2. Matches aSDomain:
                     nrpspksdomains_IE189_RS23245_NAD_binding_4.1"
                     /codon_start=1
                     /gene="rfbB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020128995.1"
                     /locus_tag="IE189_RS23245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_47330"
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="WP_189924560.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 8.5e-19, bitscore:
                     62.0, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 2.4e-19,
                     bitscore: 63.9, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 1.5e-18, bitscore:
                     61.2, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLLVTGAAGFIGSAYVRGLLARDPAVRVTVLDKLTYAGNPANLP
                     TGHPRLEFTHGDICDADLVDRVTAGADQVVHFAAESHVDRSIDGAGAFVRTNVLGTQTL
                     LDAALRHGVGPFVHVSTDEVYGSIETGAWTEEQPLSPNSPYAASKASSDLIALAHHRTH
                     GLDVRVTRCSNNYGPRQYPEKVIPLFVTNLLDGEQVPLYGDGRHVRDWLHVEDHCRGVD
                     LVRTKGRPGEVYNLGGGTQLSNRELTGLLLDACGAGWDRVRHVEDRKGHDLRYCVDWTK
                     ARDELGYRPRHDFTAGLAGTVAWYRDHRDWWEPLRPQARTP"
     aSDomain        22050..22559
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS23245_NAD_binding_4.1"
                     /evalue="2.70E-19"
                     /label="IE189_RS23245_NAD_binding_4.1"
                     /locus_tag="IE189_RS23245"
                     /protein_end="174"
                     /protein_start="4"
                     /score="61.2"
                     /tool="antismash"
                     /translation="VTGAAGFIGSAYVRGLLARDPAVRVTVLDKLTYAGNPANLPTGHP
                     RLEFTHGDICDADLVDRVTAGADQVVHFAAESHVDRSIDGAGAFVRTNVLGTQTLLDAA
                     LRHGVGPFVHVSTDEVYGSIETGAWTEEQPLSPNSPYAASKASSDLIALAHHRTHGLDV
                     RVTRCSN"
     gene            23003..23920
                     /gene="rfbD"
                     /locus_tag="IE189_RS23250"
                     /old_locus_tag="GCM10010496_47340"
     CDS             23003..23920
                     /EC_number="1.1.1.133"
                     /GO_function="GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (48-154). E-value: 1e-10.
                     Score: 33.1. Matches aSDomain:
                     nrpspksdomains_IE189_RS23250_NAD_binding_4.1"
                     /codon_start=1
                     /gene="rfbD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020128996.1"
                     /locus_tag="IE189_RS23250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_47340"
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="WP_189924562.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 2.7e-107,
                     bitscore: 352.5, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 3e-06, bitscore:
                     20.9, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRWLVAGAGGMLGRDTVQELLRRGEDVTGLDRTALDVTRPTSVAA
                     AFGAHRPDVVVNCAAHTAVDDAETDDARALLVNGEGPRLLAAACAAHGARLVHVSTDYV
                     FDGTARTPYAEDHPPSPRTAYGRTKLAGERAVRAVLPDASVIVRTAWLYGVHGRSFVRT
                     MLDLEARRDTVDVVDDQRGQPTWSADVAVRVADLGPLAGRGASGVFHATAAGEATWYDL
                     AREVFRLTGADPDRVRPVTGDHHPRPAPRPAYSVLSHGRWREAGLPPPRDWRTALRQAL
                     PLIRGASPEPVPSEEPEESLRETP"
     aSDomain        23147..23464
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS23250_NAD_binding_4.1"
                     /evalue="1.00E-10"
                     /label="IE189_RS23250_NAD_binding_4.1"
                     /locus_tag="IE189_RS23250"
                     /protein_end="154"
                     /protein_start="48"
                     /score="33.1"
                     /tool="antismash"
                     /translation="AHRPDVVVNCAAHTAVDDAETDDARALLVNGEGPRLLAAACAAHG
                     ARLVHVSTDYVFDGTARTPYAEDHPPSPRTAYGRTKLAGERAVRAVLPDASVIVRTAWL
                     YG"
     gene            23907..24710
                     /locus_tag="IE189_RS23255"
                     /old_locus_tag="GCM10010496_47350"
     CDS             23907..24710
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019057839.1"
                     /locus_tag="IE189_RS23255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_47350"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_189924564.1"
                     /transl_table=11
                     /translation="MKRHEFLRELHKVTANRNYLEIGVNDGRSLRLSRVPSIAVDPAFK
                     VTSELRCDVHLVRATSDDFFARRDPLAHLRGGRHPLRNLARGRHPLGHWRRATLDLAFI
                     DGMHLFEFALRDFINVERHCDWSSVIVLDDMLPRGVDEAARDRHTTAWTGDVYKLTEIL
                     SRHRPDLVIVPVDTEPTGQLVVFGADPRNPVLRRRYHEIVAEYEVPDPQKVPEDVLERV
                     RAVRPGTLLRAGFWKPLVRARNRGLDRSRGWEPLRGALERAAVSR"
     gene            complement(24700..25299)
                     /gene="rfbC"
                     /locus_tag="IE189_RS23260"
                     /old_locus_tag="GCM10010496_47360"
     CDS             complement(24700..25299)
                     /EC_number="5.1.3.13"
                     /GO_function="GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA]"
                     /GO_process="GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="rfbC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) dTDP_sugar_isom"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020128998.1"
                     /locus_tag="IE189_RS23260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_47360"
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="WP_189924566.1"
                     /sec_met_domain="dTDP_sugar_isom (E-value: 9.1e-62,
                     bitscore: 202.1, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPLGIEGAWVLEPRVLPDGRGSFHEWFREPEFRAATGHGLGLAQ
                     ANCSVSRRGVLRGVHFSDVPPGQAKYVTCVRGAVLDVVVDLRVGSPGFGRWEAVRLDDV
                     TRHAVFLAEGLGHAFLALGDEATVVYLCSTGYAPEREHGVHPLDPGLGIDWPRGVEPVL
                     SPRDAAAPSLAEARASGLLPSYASCRDHYRALRLSG"
     gene            complement(25304..27238)
                     /locus_tag="IE189_RS23265"
                     /old_locus_tag="GCM10010496_47370"
     CDS             complement(25304..27238)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020128999.1"
                     /locus_tag="IE189_RS23265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_47370"
                     /product="glycosyltransferase family A protein"
                     /protein_id="WP_189924568.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.2e-34,
                     bitscore: 112.6, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVKVSVIVPVHNPGPYIEECLASLLRQSLPPDEYEVIFVDDGST
                     DATPARLDAAAADDGRIRVVHQENSGWAGKPRNVGIDLSRGEYVMFVDDDDHLGDEALE
                     RMYAYGVANDADVVVGKMAGKGRSVPVELFRLNRPHATVANAPLIDSLTPHKMVRRAFL
                     DRTGLRFPEGRRRLEDHVFVTEAYLRAGNVSVLSDYVCYYHVRRDDAANAGLQRFDPVG
                     YFKNLREALDVVERYTEPGPLRDRLFRRWLRVEMVERLRGRRFLGLPEDYRRHLFDEIH
                     SVVVERFGPGVAAPLQPAQRVVAALAAEGRYDDVVAFAQWEAGVALAVDPEDVEWRGGT
                     LRITFAAELTHDGAPMTFPSAGGSPQWPPHDVAEAVRWLGTDIVGRFDRAVPDLLLRER
                     VGAAQYFQPVDVVRETVPAGGDGSLVRLVLRATATVDPASALSGGPAGEGLWDVFVRLG
                     LGGWTKELRLGPAHRHGRPAPPAAVVAGRVVLPYWTDRYASLALDVGHAGNRLGLGRVA
                     AGDVTVTGERLHVVLPLHVPEAAGVLLRLTAAKSGGSREVFGTLSPGGRMAAALPVADL
                     TGRTWLTTVCLTPDADGARFHPLPFALHVDADGVLVVPAPQPGGARRLARRMRRAAYRA
                     LGRITARRK"
     misc_feature    complement(27387..27401)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.25"
                     /tool="antismash"
ORIGIN
        1 gccgaggcgc tgctggagct cacggctgcg cgcgaactgc gcggcccagg cggcgtacgc
       61 gtagttctcg gcggccgcca cccgcagctt cggcagcccc cgcagggtct ggaaggcctg
      121 gttgttcagc ttgttggaga gcaccacgag ccggcgctgc cagcgcacct gccacaggcc
      181 gagccccagg aacacggagg cgacgacgac cagcatgccg atcgcggcca gcgccatcgg
      241 cacgctgtac cagagcagca gccccaggtt catcgccccg acggtgacgg actgcgccac
      301 cgacggcccc agtcccgcca gcagccggcg gatcgcgctg acacccatcg cggcactggc
      361 cagttcaccc gtggaacgcc gggcgaagaa ctccgtcggc agccggagca gccggtccca
      421 caccgcgggc tggagggtcg cctcgatccg gccctccatc cgcaggatgg tcagattctg
      481 gagcagcgtg aacgccgcgg ccaccacgcc gccgatcatc accgccagac acacctgcac
      541 gatcaggtcc tgctgcgccc tcggcacgta ctcgccgagc accttgccgg tggcgatcgg
      601 caccagtgcc ccgatcgcca ccgtcaccag accgctgacc agcaggttcg tcaggtcgct
      661 cgccgtgccg cgcatgctga agcgcagcag gccgagaggg ccggggccgc gctccggcag
      721 cgggcggtag aacatgaccg ccctcggctc gaactcggac gcgttggcct tctccaccgg
      781 ggtctcccgc ccggtggagg ggtgcaccgc gacatagccg ccgcgccgcc acagcagcgc
      841 caccggcgcc ccggacaggg cccggtgccc gaccagcggc cccacgtcgt cccgccacca
      901 gcggccgtcc agccgtacgg cccgggcccg gacccgggag gcgagcgcga cccgctcgac
      961 cgggtccagc cggtcgctcc cggcgcccat ccgcgccggt tccaccaggg tgatcccggc
     1021 cgcccgggcg acgagccggc aggccgcgta ggtggcgtcg gcgtcggccg ccgtggcccg
     1081 ccggtccgcg cccgcaccgc cgtcacgggc gccccggccc cgcgggccga tcgaggcgag
     1141 cagggtccgg tcggcctgcg cgcggaccgc ctcacccgcc ttgatcccgg cggccgtccg
     1201 ggtctcgtgg gtgtgttcca gctcctcgat ccagcggtcc agcgcggtca gcaaccggta
     1261 ctgctggtcc accatgctct gccacaccgc ggggtccatc agcaggtcgg cggcggcctc
     1321 ggcgccgtac agcgcgccgt actgcacgct gcccggcggc acctgcatcc agaagacgtc
     1381 gtcgtcgccc tgcgcccccg ccccggcccg cacgggtccc gccccgtccc cggccgcgga
     1441 ctcgcccgcc atcggcgcct ggaagaggac cgacagaccg cggccgaccc cgagggcgag
     1501 cgcgtactcc agcgggctcg aagccggcgg cacgtactgg gggttgccgt acgcgtcgta
     1561 ggaccaggtc tcggtgctcg cgggctggta cagctcacgc agcccgacgc ggtgcacgac
     1621 gcagtcgcgc agcggacgcg ccacgagggt gtggcgggga ccctggaccg gaccgagcag
     1681 cagggcccct gcctccagcc ggcccaggtg gtgccagtgc ccctgctgtg cggcgtccac
     1741 cgcgaacagg tccagcgccc ccgacgccac cacccacagc gcctgcggac cctccaggtc
     1801 cagacggccg gagcccgcgc agtcgatccg ccggcccagc tgccccagcg cggcgagcac
     1861 gtcgtccgtc ccggatacgg tcgtcatctc atcgctccct gaccagcgcc gcgtacgcgc
     1921 cgccgcgtgc caccagttcc tcgtgccgcc cgcgctcgac gacgctcccg tgctcgagga
     1981 cgacgatctc gtcgctgtcg cggaccgtgc tgagccggtg cgcgatcacc acgcacgcgc
     2041 aaccgcgccg gcgcaggttg tccatcacca cctgctcggt ctccgcgtcc agcgcgctgg
     2101 tcacctcgtc cagcaccagg atgctcggcc ggcgcaccaa cgccctcgcg atctccaggc
     2161 gttgacgctg accgccggag aagttgcggc cgtcctgctc gaccctgccg tggatgccgc
     2221 cgggccgccg cgcgaccgtg tcgtacagcg ccgcgtcccg cagcgcttcc acgaccgcgt
     2281 cgtccgggat cgacgggtcc cacagcgcca cgttgtcccg caccgagccc tcgaagagga
     2341 acacctcctg gtcgacgaag gacacggagg aggcgagcgc cccgcgcgag atgtcctcca
     2401 gccgctgtcc gtcgacccgg atcaccccct cccagggcgt gtacaggccc gagatcagcc
     2461 gggacacggt cgacttgccg ctgcccgagc cgcccaccag cgccacctgc tgtcccggtc
     2521 cgaccgtcag atcgaaaccg ctcagcagcg gctggtccag ggggctgtag ccgaaggtga
     2581 tgttctccag ctcgacgtga ccgtgcagcc gccgggtgga gtcgccgccg aagcggcggt
     2641 cgtagagcgg gtcggcgcgg aagttctcca cgtccttcag ccgggccacg tccgccgcga
     2701 agtcctggat ccggcccgcg accccgttga gacgggtcag cggcgcggtg aaacgggcga
     2761 ccagggcctg gaaggcgacc agcaggccca ccgagatgtg cccctcgatc gcccgcatac
     2821 cgccgatcca caggatcagc gcgctgttga acgtcgcgag cgtcggcgcc accacaccca
     2881 gccaggcgct cggcacgccg agccgctgtt gctcctccag cgtggtggcg tgctgcccgg
     2941 cccacttgcg gaagtacccg tcctcgccgc ccgtcgcctt catcgtctcg atcagctgga
     3001 gcccggtgta cgccgtgttc gtcagccggg cgttgtcggc ccgcagtttc gccgtccgcg
     3061 tcgcgcgcag ccggacgacg atccgcatgg cgacgatgtt gagcagggcc acgccgatcc
     3121 ccacgaacgt cagctgcggg tcgtaggtgt agaggaggac cgcgtacagg acgacgacga
     3181 cggcgtccac gcccgccgac gccagatcac gggccagggt ctcggcgacc gcgtcgttcg
     3241 actggagacg ctggaccagg tcggccgggc tgcgctggga gaagaacgtc accggcagcc
     3301 gcagcagatg gcgcaggaat cgggcgctgg acagggtcga ggagatgatc cggccgtggt
     3361 gcagattggc ctgctggagc caggtcagga ccaccgtgag cgccacgcac gtcgccatag
     3421 aggcgaacag cacgcccagc agggaggtct gccggccgat caggaacatg tcgatgtagg
     3481 tccggctgag cgccggtacg gccgacccca ccaggaccag cagcaggctc gccagcaccg
     3541 ccgcgggcag ggtgcccgcg gtaccgcgca gccgcgccgg catcgcgccc agcacaccgg
     3601 gtcggcgccc gccccgctcg aagtcctcgc ccggctccag caccagcacc acgccggtga
     3661 agctgccgtc gaagtcctcc atcggcacga accggcgccc cttgccgggg tcgttgatgt
     3721 acacgccccg gcggccgaag cggcggccca ggccctcgta gacgacgtag tggttgaact
     3781 cccagaagag gatcgcggga gagcgcaccc cggcgagggc cgccaggtcc atctgcatgc
     3841 ccttggccgt caggccgtaa ccgcgggccg ccttgagcag gttgctggcc cgcgagccgt
     3901 cgcgcgagac accgcacgcg atgcgcagct cctccagcgg gacgtgccgt ccgtagtgcc
     3961 cgaggaccat ggcgagcgag gccgccccgc actccaccgc ctccatctgg agcacggtgg
     4021 gcgtgcggac ggtcttcgtc cggctcttgg ggaccgtccg ccggggcggc gcggcgcgcc
     4081 gcctgccgcg ggtctcccgc gtggcggtca cgggagcagc cagtcgacgg gacgctggtc
     4141 ggccagccgg atggaacccg tgcccatcgt catcgacgtg agggggtacg gggggccgtc
     4201 ggcggtggac cacgcgtagc cgctcttcgt cgtcgccgac cggtccagcc ggacgaggac
     4261 cgcgacgggg cggccgtcct cggtgaactg ctcgccgagc ctgctgtcgc cgaggaaggc
     4321 ggcgatcgcc tgcgccgact gggccgcgcg gtccaccgac ttcacatggc cgcgcagcac
     4381 gccgtactcc tgggagggca cggtctgcac ggtcaggtcg acggcggcgc cctcggggac
     4441 ggaggcgccg ttctcggccg ggacgtacac cgtggcgtac aacgggtcgt cggcgtgcgc
     4501 gaccttctcc acggcggcga cgttcgcgcc ggtggagacg atctgcccga tggtggcggc
     4561 gagggcgctg atccggcccg cggcgaccgt gcgcaccacg gtgtcgcccc gctccgtgcg
     4621 caccttcagc acgggtgagc ccgcgggcag ccgttcgccc tccttcgcga ggaccgcggt
     4681 gacctggccc gccgccgggc tctggaggat gtagctgccc tcaccgtggg tgaggacggc
     4741 gggcgcgctc accgtggagg agaccgaacc ggtcaccgcc cacacggaag cggccgccat
     4801 gacgacgatc gtcacggaca gcaccagcca gccctgcggg cgcgcgaaac gcaccggcag
     4861 gtcgagctcc tccggtgact ggagcttggc gagagcctgt tggcggaact gcacggggct
     4921 tacctcggga ggttcagggc accgaagagt cccggagccg ggtgacggct ccgggactcg
     4981 aaggagtcac aaggacgcga tcagagaccg gcgaccaggt tggtgaccgg ggccgtgttc
     5041 aggccggtga caccctcgac ggtgccgacg accgtgttga ccaggccgga gaccggggcg
     5101 acgccgtcca ccaggccggt gacggtgccg accgcgttca gggacagacc gccggcgacg
     5161 ttgtccagct cggcgtcgga gatctcagcg gtctgaacct ggggggtgga gttcatggtg
     5221 gaacttccct tcacatggat atctcatcag gggggagcgg ccccctctgg ggacagatga
     5281 cggccgcgac cacgggcacc ggcccccgtc gccgggggac gcggtggccc tgcggtgcga
     5341 tggatcaaag caggtccgtg accggcgcag ccaatcaatc acggccctca cctgcggact
     5401 tgtgtcacgc aagcgtcgaa cggtgcagga gtgcccacca cttgtcgcca gcttcttcac
     5461 accacggcgg gcatccgctc ggatgagcgg tcggcgccct gacggcgaat gggacactcc
     5521 ggccccaaag ccgtgaccgg cgccgcgcag atgtgcagaa gctccgcgcg cggtgacccg
     5581 cttgggcatt cgctgtgcag attccctgga gcggggattt ggcccgccgt tctcgacgca
     5641 cggtcatgtg ccgtgcgcgg agcgtgagat gtcgatccgg ggcggagcgg ggacgcacag
     5701 ccggcgcaca tgtctgcgat cgcgacgccg gggccccgga ccgccggaac cgatcggatc
     5761 aggccatccg gaccggtcgc ctccggccgg aacggactgg gccgccccgc cgtcttcctc
     5821 tcttcggaca cctgcccgcg accggcgcgc ggatcccggt gccccgtgcc ccgcccgtcg
     5881 cccgaacccg ctcccgggac cctcccgcac tcctgggcgc aactctgtga acagggagaa
     5941 cctggggatc gaccgctctc gccgacgagt cggacgagtc cgtcccgcgg ggtcgcccgc
     6001 ggtgccgatc cggccggggc ggtcctgtcg gcttcggcgg ccgacgtcga catatgggcg
     6061 attgttccgc gccccgtgcg ccccgacccg ggtcatggcc gattcacgtg ttggcaaagg
     6121 aagttggcaa acgcgattga acgcaacccg cgcaccccgc gtactcatgg ccaaccaggc
     6181 gccgctgtac ggagctgccg gaccccggca gccagacccc gtcccccagg aggtcgagtt
     6241 ttttgagtca caagcgagtt acgaagcgta aggccatcat cgcggcaggc ggtgtggcgg
     6301 cgctcggagc ggcggccatc ctgcttcccc aggccaacgc ctcccaggac ggcacgtccg
     6361 acggcgccgc ctcggtgaag accctgaagg cgggcgacgc ctcggacctc gcgtcccagc
     6421 tcgagaagct gctcggtgac gccttcgccg gttcgtacta cgacgacgcc ggcaagcagc
     6481 tcgtggtcaa cgtcgtgaac gtctccggcg acaagaacaa cgtcgtcgtg caggccgaga
     6541 aggcgggcgc caaggtccgc gaggtcgaga acagtaaggc cgaactcgag gccgccgcca
     6601 agacgctgaa ggccaaggcc accgtccccg gcacctcctg ggccgtcgac cccaagacga
     6661 acaagatcct cgtcaccgcc gactccacgg tcaccggcaa caagtgggac caggtcgact
     6721 cgaccgtgaa gaccctcggt tccggcatgg ccaccatcag gaagtcggcc ggcaccctca
     6781 agcccctggt ctccggcggc gacgcgatat tcggcggcgg ggcgcgctgc tccctcggct
     6841 tcaacgtgac ggcgggcgac ggctccccgg ccttcctgac ggccggtcac tgcggggtcg
     6901 cggccgaaca gtggtccgac agccagaacg gccagcccat cgccaccgtc gaccaggcca
     6961 ccttccccgg tgacggcgac ttcgcgctcg tgaagtacga cgaccccaac acgcaggcgc
     7021 ccagcgaggt caacaccggc cagcagacgg tcgccatcag ccaggccgcc gaggcgacgg
     7081 tcggcacgca ggtcttccgg atgggcagca ccaccggcct caacgacggt caggtgctcg
     7141 gcctcgacgc caccgtgaac taccccgaag gcacggtcac cggcctcatc cagacggacg
     7201 tctgcgccga gcccggcgac agcggcggct cgctcttcac ccaggacggc caggcgatcg
     7261 gcctgacgtc gggcggcagc ggcgactgca cggtcggcgg cgagaccttc ttccagccgg
     7321 tgaccaccgc cctcgcggcg gtcggcgcga cgctcggcga cggcggtgcc ggcgccggtg
     7381 acgcggccgg cggcgccggt gcaggtgccg gtgcggtgga cgagaacggt gacggtatcg
     7441 acgacaacac gggcgaggcc atccagggcg gcggcgatgc cggtgccggt gcggtggacg
     7501 agaacggtga cggtatcgac gacaacacgg gcgaggccat ccagggcggc ggcgatgcag
     7561 gtgccggtgc ggtggacgag aacggtgacg gtatcgacga caacaccggt gaggccatcc
     7621 agggcggcgg cgacgcggcg gccgacggcg gcgccgacca gaacgcgaac ggcggcgccg
     7681 acgcgtccgg cgacggccag gaccagtccg gaaacggcaa gaaccgcaag ggcggccagc
     7741 aggacggctc gggcgtgaac gagtcgcact gacccaccag cagcgcgagc ggtccggtcc
     7801 tccggcgggg gccggaccgc tcgcgtgtgc gcgcgaccac ggccgtcagc cgtccgccac
     7861 ggcccgcagc agcagcaacg ccacgtcgtc cagccgctcc tccgccgtcg cgtgccgacc
     7921 caccaggtcg tcggccacct cctccagcgg acggttcccg gcctcgccga gccgccgccc
     7981 cagctccgcg accgcgtcct cgatgtccac ccccggtgtc tcgatgagcc cgtccgtgta
     8041 gagggcgagg acacagccgg tggtcagctc cacctccgtc gtcggatagg ccgccgcgcc
     8101 gtcgatcccc agcagcggac cacccgcgag gtccagcacc cgcacccggc cgtccgcccg
     8161 gcgcagcagc ggcgggggat gcccggcccg cgccatgacc gcgcgccccg cggccggatc
     8221 cagccgcagg tacagacagc tcgcgaacag ctcggaaccc aggtcgatca gcagccggtt
     8281 cgtgctgcgc atgacctccc cgggctcctg ccccaccgtg gtgtacgcgc gcacggcggt
     8341 gcggatctga cccatcagcc cggccgccgt cacgttgtgc ccctgcacgt caccgatcac
     8401 ggccgccgcg agcggggccg agggcaccag gtcgtagaag tccccgccga tctccatccc
     8461 gcgggtcgcg ggcagatagc gggcggtcgc ctcgatcccg gcgagcgagg gcagcgaggg
     8521 cggcagcagc gccgcctgga gcccgtgcgc cagccggtgc ttgacgtcgt acagcagcgc
     8581 ccggtccagg gcctgcgcga tcagcccggc gaggctggtc agcacggccc gctcatgggt
     8641 ggagaagacg tgcggttcgg cgtaggccag cacacaggcc cccaccgggc ggccggaggc
     8701 gatcagcggc aggaaggccc acgcggcgaa gccgtcgggc gaggaccgcc gggccgggta
     8761 caggcgttcc aggtgctgcc gcgactcgaa gaaggccggc acgccgtggg tgacggcgtg
     8821 cgcgccgggc gtcggggaac tcaggggcgt ccggtcgaac cgctcgacga gccgcggctc
     8881 gggatacccg tggtgcccga gcacgtgcag ccggccggcc cgcgcgccga gcagggccag
     8941 ggcctgactg cccaccgcgg gcgcgatctc gtccgccacc agcccgacca cgtcctggac
     9001 gctcaccgtc tcggtgagcg ccccggccag actgagcgcc tgcgacatcg acaccagccg
     9061 ggtcggcgcg tcctcggcgc gcgcgtcgga cggccgcgtc tccgagaccg cccgggcgcg
     9121 gctgatccgc acgctgatcc cggtggtgct cggatacagc cggagcgaca gccagtgcga
     9181 gggcggccgc agcgccacga acgaggtggc ctcctggctc agcagcgcgg cccggtagcg
     9241 ctcctcgtac aacgggtcgt tgagccaggc cacggccgcc cacagctgcg acccgagcag
     9301 ctcgcccacg gggaccccga gcagctcggc cgccgcctcg ttggcgaagg tgatccgtcc
     9361 gctcacgtcc agcgagcaca tcccgtacgg caggcgcgcc accatccggg ccgcctccag
     9421 cgggcccagg gtgtcggaca cgccgctcac cgaaaggtcc agcaggtcgg actcggcccg
     9481 caccgagcgg ttctccgacg ccgcgcgttc cagccgcagc gcgagccgct cgcaggccgt
     9541 cgtcagttcc cggcgctcgc ggtcggacag ctccggaggg tgcgaacccg gccaggtcac
     9601 gtacaccgcg ccgtggaccc gggagggacc gagcaccggc agcgcggcga gtgcgaaggg
     9661 atagggcagg acgacggcga tccggggata gcggcgggcc atctcctccg cccctcccac
     9721 ccagaccagc cgccgttcgc gcaccgcttc ggcgaccggg atcggcgcgc tgacccccac
     9781 ccgctcccag ggcgcagcga aggaccgggg cagccccgcc atcaccgcca tctccaggac
     9841 cggcccgtca cccggacgca ggtacacggc tcccgagtgc gctccgacgg cgtccatcat
     9901 cgacgtcagg gcgagggaga gcagcggccg gtccaccggc gtccacacgg gcgcgggcgc
     9961 ctgaccggac gacgtctgac cgtccgacac ggcgaccacc tcctcgcccg gcgccgcgcg
    10021 agcccccagg ctccaaatct gccccctggc ggcgcggcgc gcacggcgag cggcccgccc
    10081 gcgaagtccg cgcggtaccc cgtcggccct tgtccatgcc ccctcggccg aagcgcggga
    10141 cggcgtacgg gcgccccgcg tgcgcccccg cgcaacccga tggccggatc ttcgcgctgg
    10201 gaagcgatcc ggcggccgaa gaatgggcac gcgttcagca ccacggacaa cagcaggcaa
    10261 ccggcgcacg gtgagctgaa ggggcggcag tgatccaggt acttctggtg cacgacgcgt
    10321 gtctggtcag atcggttctc gcacagtggc tgtccaggga acccgatctg cgggtggacg
    10381 acgtgccgtg gcgcggcgcg gccggccggg tcggcgcggt gcgccctgac gtgtgcgcgg
    10441 cggacctcga ctgctccgag gcgtccggcc tcccgccgct gggcgagtta tgcccgcgcg
    10501 gcggcgggct ggtccctccg cggcttctcg tgctggccag cgcgcaccgg ccgggcctgc
    10561 tgaaacgggc tctggaggcg ggggcgctcg gctacgtcga caaggagggc acgcccgaac
    10621 agctggtgag cggcatccgc aaggtcgccc ggggggaacg tttcgtcaac agctcactcg
    10681 gcttcgggtt cctgaaggcc gccgagatgc cgctgacccg acgcgagctc agcgtgctga
    10741 ccctcgccgc cgagggggcc tccgtcgccg agatcgcggg gaacctgcac ctgtcccacg
    10801 ggaccgtgcg caactacatg gcggcgatca cccgcaagac cggcgcccgc aaccgcgtcg
    10861 acgccatccg gatctcccag gggcagggct ggctgtgagc cgtccccggc ggcccctgcc
    10921 cgcgaggtct ccccgaccgc ttcccagccg ccgacgagat cgcggtacag accgcagtcc
    10981 cgcagcacct tctggtgcgt gccgagggtg gtgcgcggcc cgtccatgac cagcacccgg
    11041 tccgcccgcc cggccgagct gatgcggtgg gcgacgacga ccagggtgcc gcccgtccgg
    11101 gcggcgaacg ccccctccgc gcgagcctcc gccgccgggt ccagatggct ggtcgcctcg
    11161 tcgagcaggg ccagcggcgc ggacgatagg tacgcgcggg tgagggcgat cagctggcgc
    11221 tcgcccgccg acagcgccgc cggttccacc ggcgcggccg gtccgcccag cctgtcgagc
    11281 aacgggagca gtccgaccgc gtcggccgcc gcgaggagct cgtcctcggg cacggcgtcc
    11341 tcgcgcaggt gcgtgaggtt ctcgccgagg gtgccggtga acacgtacgc ctcctgcggg
    11401 atcagcaccc gccgggcggc ggcgtcggca cccggtaccg gtcggccgca gatccgtatc
    11461 tccccgcgca ccggttccag cagccccgcc accagcgcgg tcagcgtgga cttcccgatc
    11521 ccgctcggac cgactacggc cagatgggcc ccggcgggca ggtcgagcgt gaggccgtcg
    11581 accacgggtg cggcggcggc gccgtaggcg aaggtgaggg agctcagggt gagcgcggac
    11641 ggcacggaac cggacgcccc cgcgagcggc gggacccacg acactgcggc ccgcgctgct
    11701 tccgccttcg gcgcgtctgc cttcgacgct cctgcccgag gcgccccgcc cgcccggtgc
    11761 gggctcggcg gccgtgggcc gcacaccgct cgctcgtcgg cgcgggaccg ggggcccggt
    11821 cccgcgccgg agtccgtcag gcggcgcagg acgaccgtca gtcgggagcc gctggtgccc
    11881 aggccgtgga ccagggcggt gagggccggg acgagggact gggtgacgta ggccagagcg
    11941 ccgaccaggg cgccggggga gacaccgtgg tccaggagcc atgggccccc tgccagcagc
    12001 aggaccagcg ggagccggcc gccgagcgcc agacagacca cccgtgccac gccccaccgt
    12061 gccaggaccc gcgccgcctg cgactcggcc tcgaccaggg cgccggtgtc ccgcgcgatc
    12121 cggtcctccg cgccggccgc cgtgacgtcc cgaagccccg ggcagacgac acccaggtcc
    12181 tgcgccagcg cctcgtcggc ggcgaggaac ctctcctgcc gacgggccag gggccgcagc
    12241 gtcacgaaga acaggcccac gccggcggcg agcggcggcg cgaccaccag gagcaggggc
    12301 ggggcgagcg aggccagccc ggccagggcg ccgacgcagg tgaacacgaa cgagcgcgag
    12361 accatcacca ggcccgcgaa gctgtcccgg gcgatctcca cctgctgggt gaggcgcgag
    12421 agcgccccgc cgtccgcctc gcgcaccccc gtgcgcacca cccgggtgac gagccggtcc
    12481 cgcaagggct ccaccagcgc ggcgaccgcc ccgtagaccc ggccggtgcc gtacgcgccg
    12541 gccagtacgc ccagtccggc cacgccgagc caccacagtc cggtcccggc ccggccggcc
    12601 aggaaaccgt cgtccagcgc acgggccagg gcgtacccga gcaggaaggt ctgcccgctt
    12661 tccagcaccg accagccgac gagccccgcg agggcccgcc ggcggtccag caggaagcgg
    12721 atcccctcgg cccgcagccc gccccggccc accggcccgc tcaccgccgt gtcaccgggc
    12781 cgcacccgtc ctccgcccgc gcgttcgccc gcgcctcggc ctgtgcatcc gcctcggcct
    12841 gtgcctctgc ctgcgtgtcc gccggcgggg cggatcccgg cccggtgccg ttctcggtgt
    12901 ccgtcgcgaa caccttccgg tacgcggccg tccgccacag ctgcgcatgg gtgccgacgg
    12961 cccgcacccg tccgccgtcc agccaggcca ccgcgtcggc gcgggcggcc gtggaggcgc
    13021 gatgggccac cacgagccgg gtggcggtcg tggtgcggcc gaacacggcc tgcgtgacct
    13081 ggcgttcggt gacggtgtcg aggctggaga gggcgtcgtc gaggatcatc agccggccgc
    13141 cgtgggcgaa cgcccgggcc aggccgaggc gctgggcctc gcctccggag tgcggggcgt
    13201 ccgcgcagcg cgtcgcgtag ccgtcgggca gccggcggac gaagtcgtcg gcgcgcgccg
    13261 cgcgcgcggc ctcccggacc cgggcggggg aggcgctccc gagcgagacg gtgtcctcga
    13321 tcgtggcgcc cagcagggcc gggcggtcga aggcctgcgc gatcgccgcc cgcagctcgg
    13381 accggcgcag ggcggccagc gggacgccgt ccagcagcac ctcgccggcg tccgggtcgg
    13441 tgagccggcc cgccagcgcc gccagcagcg acttccccgc gccggagcgg cccaccacgg
    13501 cgagcgccgt cccgcccggg acgaccaggt cgaggccgtc cagcaccgca cggtcaccgc
    13561 ggcgcgcgct cacgccccgc agctccagcc ggcccggacc gtccgcgggc agtccgcggg
    13621 tgccgtagga aggcgcgggt gcgttcagga cctcgccgag acgggcggcc gcggcccggg
    13681 agcgggccag cccggagagc tgcccgacca ggacgccgac gcccgtggcg aggaccgcgt
    13741 aacgcgacgc ggcgaggacg tcgccgggcg acacccggtg ccgggcgagc agcaggcccg
    13801 cgacggcgac gaccccgatg tgcagcaggg gcgccaccgc ggtcgcctgc gcggcggccc
    13861 ggccctgcac ctgccacatg cgccgtcccg cccgggacag ctcgggcagc ggccgaagga
    13921 cgcgtgcggt gtcccgggct gcggtgccgg ccgcgcggat cgtgcgcgcg ccgccgaccg
    13981 cctcggtgag ggcggccgcg atccgtccct gcgcgtccag gtacgcggcc acgcacgacg
    14041 aggtgtccct ggccagcgag cgcagcagga gggtgaggac gggcgcgccg gtcagcagga
    14101 cggccgcgag ccacgggtcg atgagggcga gcgccgccac cgcgccgacg ggtccggcga
    14161 gcgcggcggg gagcgcggca cgggcgcccg gcgccgcgcc ggcctgggcg gcgccgccga
    14221 cgacccgcgc gacgaggtcc ccggcctcga agcgggcggt ggcgcgggga ccgagggcca
    14281 ggacgtgacc gagggcccgg tggcgcagga aggcggtggt cttggcgtcg agggtgccgg
    14341 tgaggacggt ctcgcccgcg tcgagcaggg tcagcagcag ggcgaggccg gcgcagcaca
    14401 gcacccaggg ggtcgcgccg ccgccggcga gcagcaggtc gagggcccgg cccagggcgg
    14461 cgggcaggag cagcgaggca ccggtcgcgg tcacgcccag cagcgccagg gcggcggggc
    14521 gcggcccgcc gtgccgggtc gccgagccga gcagctcgcc ggtcgtccgg tccatcggca
    14581 tccgctcccg tacgtttcgg aggttccgtt tcctgcggcg ggcccgggag gaccgggcta
    14641 cgggcggccc gccccctggg ggagcggacc gcccggagcg gtcggcacgg cgtgcgcgcc
    14701 gagcgcgtca gacgtgccgg aggatcacag acagagcagc acgctcgtcg cgctgacgca
    14761 ggagagcagg ctcacggtgc tgttgccgcc gcccccggtg tgctcgtcgg attccatcgt
    14821 ctgaaggtcg agcagggcca tggtgtgtcc tttcgtcggg ttcatcggtt ggatgtcaca
    14881 tcccgtgggg acgggttgcg tcacgactcc gtcggttgcc gcggagccgc gtccgagggc
    14941 cgccggtgcg gcggcgggag gaacggcagg tgcgcgtcgg cgcccgtgcc gtccgggtcg
    15001 agagcggcgg ccagggcgag cagacagccc gcggtgccgg tcccgagatc catggacagc
    15061 cgcatcatct ggtgtccggg gaaggcgagc tggccctggt agggcatcga gaaccagccc
    15121 agcgcggcga tctgcccgtc cagccgtgcc cggggcgcgt ccggggcggt ggtgcgcgcg
    15181 agatgcagga tcatcccggc gcggccctgg aagaggccgg gctgcgcgta gaagcgggag
    15241 gtggcggcgg tgcggatgcc ggcgcgagac cgctcgaact ccggctcgcc gtaagggaca
    15301 tggacggcgt ggtcgtcgag gaccagtccc acgcccacgc ttccgtcccc gaggtacggc
    15361 agggtgcgcc acccctcgtc gacctccacc gcacccccct cgcgctccac gcaggccgca
    15421 aggtcccggt gcagggcgac gcccgccgcc tccagcagcc gtcgctcgcc cgtctcctcg
    15481 tactgccgga gcaggaagag ggcggggccg ctcgcaccgc gcagcagtcc ggcccgctgc
    15541 cgccgggccg tcccgggcac cggttcgccg agccgccgta cgacgatgtc ggcggcctcg
    15601 gcggcccgct cgcgcagctc cggctcaccg gtacggcggg cgaggtcgcc gaggacgagg
    15661 cccagtccgg ccagtccgcc gtgcaggtcc gaggagaggt tctgccaccg ctcgcgcagg
    15721 atgccgtcga ccaggtcgag cgcccgcccg cggtgaccga gcagctccag gacgtgggcg
    15781 acgcccgcga ggccgtcgta caggcccagg ggagtgcccg tcggggccgg cgcggtgcgg
    15841 tcgaggagcc agcgctcgcc gtcgtcgaag cgttcggcgc cggtcgcccg cagcgcgtac
    15901 agcacgccgg ccgccccgtg cgccaggccg agaccgccgc cgtcggagaa ctgcgcgacg
    15961 tccccgggga agagccggtc gtcgcgttcc ggggtcgccg acgcgaggat cgccttgacc
    16021 atggagtcgc ggctgtgcgg ccagtcgccc ggctccaccc ggaaggccgg tgccgcgggc
    16081 agccggacgg cggaccgcgg cggcgcggcc ggaccgctcc cgcccgtcgc cggcgcaccg
    16141 gagggaatgt cccgggtgat ctcggcgacc gccgcgtcca ggaactcccg gggcacgtcg
    16201 gggaactgct cggcgatcac ctcggcgaga tgcgccgcct tgccccggtc gaccacgaac
    16261 aacgtggtga ccggaaggaa cagcgcgagc cgcagacacg ccagcgcgta gcggtcgaca
    16321 tcggcgccgc gccggtcggg cggtgcgaag aagcccgggt gggccacgat ctgccggccg
    16381 ttctccccga tcggcgccgc cgcctcgaag tcgatgagga acaccgactc gtcgtccggc
    16441 gcgaccatga tgttgaagac gtgcaggtcg ttgaagacga tcccgcgcgc gtgcaccttc
    16501 tccaccgccc gctccaccga ccggtggacc cgtaccgccc accgtgtgta ggcggcgacg
    16561 gccccggggt cggggtccgg gcacagcagc ggatgccgtt cggcgaagaa cgcgttgagc
    16621 ggccggccct cgaccaggtc catcaccagg aagcggtggt cgcccagggt gaaccagtcc
    16681 cgcacctcgg gcaccacccc ggtgcccgcc accgcctcca gggcgtgctt ctcccgctcc
    16741 agccgggtga tcgcgtccgc gccgtccgcg gccaggccgg cgtgcgggcg gccctccttc
    16801 aggaccacct tgcgcccgtc ccgggtgtcg gtgcccgcgt agaccccgcc gccgttggag
    16861 aagtgcagcg ccttctcgat gcggtagggc agctcgccca ccgtcgtcgt gttgcgggcg
    16921 gccaggtgcg gctccaggaa ggggggcagc gtcacccact ccggcacctg gaaggagggc
    16981 gcccgccggt ccgggaccag ggtcccttcg ccgtcgagca ccgcgagcac gagcgagccc
    17041 cggtcgtcga cgacgtacct gcgtgcgaac gcgccgtagc ggacgtagag gggaccctcg
    17101 ccccagcgca ggtcggtcag gatgtagggg ccctcgaagc cctccagcag cgcgcccagc
    17161 tcgcgcagca ccgtgtgcaa ccgctcctcg tcgcccgggt agaccgtgac gaacttgccg
    17221 ctggtgtcgc ggcccgcgta cttggtgttg cgcagatgca gcaggtgcgg gcccggcacg
    17281 aacttgaagg ggatgcgccg cgggacgcag tagtcccaca cgatgcgtgc gacgtcgtcc
    17341 gcgttcgccc gggtggccga ggcgtggatc ttccagccct gggcggggcc ggccaccggg
    17401 gacccgtccg cggcgagcgg agtcagggcc agccagtcgc ccgtccgcgc cgacgtccag
    17461 ccgctgggga ccgggcgcag ggccgtgtcg aacagcggag cgggcccgtc gccggtcagc
    17521 cggtcgggtg tctcgtagaa gtgcgcgtcc gccagcgcgt acacctcgta ccgcttgtcc
    17581 atgcgtcccc tccgtgtcac ggcttgcgtg gccctgacaa gagactcgca aggggaggag
    17641 gggcgcggac agtcacgcct gtcacgacat ccctgtgcgg aacgcatgag taaagacatg
    17701 ttcgatccgt ttcgagcacg aaccgccctc gccgccccgc ccggcgctcg ccgaacggcc
    17761 acaggggctg cgccccggga cccgaggcgc tgtaatggcg gacgtggtca gtgagggtgc
    17821 cgcggagcgc agaacgggac ccccgcgcgc cgaaatcgca ctcgaggcga tcagagccga
    17881 tcccgccgcg cccgaccggg tgcgccgcac cctggaacag gcactcgtct tcgcgggcgc
    17941 ggccctcgcc gcgctctaca cgccggcgca gggccggctg ctccggctgg tcgactcggc
    18001 cggcgcgccg aggaccctgt acggcctgcg cgaggactac ccgctcgacg gggactcgcc
    18061 ggtcgccgcc gccctgcgcg ccgaccggcc ggtgtggctg ggccccgagg acctcgccgg
    18121 tgcggccgac caccccccgg cacagcgcac gcccgcgggc gccgtccacc tggccgtcct
    18181 gcccgtgcgg gacggcaggg gcggctgcct gctcgccgtg cgcgagcacc ccggcggctt
    18241 cggccccgac gaccgggcct gcctgcgcct ggtcgccgac gccgtcgcgc tcctcgcccc
    18301 ggccgtcacc gccgaggacg gccgaccgca cccggacgcg ttcagcctgg ccatggacac
    18361 cggccgcgtc gaggtcggcg acgagatcct ggacctgttc gggatgggcc gggccgactt
    18421 cgacgggcgg gtcgagaccc tcctcggact caccgtcccc gaggacctgc cctcgctgat
    18481 gtccgtcgtc gaggccgacc acatgtcgat cggcgaccgt gaactggagt tccgggtgct
    18541 ccagcccacc gggccgccga ggtggctcag gctccgcgga cggctgctgc ccggcggcgc
    18601 cgaccgcgcg gcacggctcg tcggcaccgt caccgacgcc tcctccctgc gcgacgaggt
    18661 caccgacgtc tcccgggtcc agcggctggc caccgcgctc gccaccgccc gcaccgtcgg
    18721 cgacgtcagt caggcggtcg tcgccgccct gcgcaagccg ctgcgggccg accggatcgc
    18781 gctcgccgaa ctggagaacg accggctcgt ggtcaccgtc ctcgacccgc ccgagcccga
    18841 cgcctggccc gagctgtggc agctggagtg gcgcgccgaa tggcccgacg cgcccgtacg
    18901 ggccatgccc accctcgccg cggccctgcg cgagggccgg gcccgtatct ggcccgccgg
    18961 caccgccctc gaaccggccc tcgccgaggt cggccccggc gggctcggtg tgctgccgct
    19021 ctccgccggc ggccgcacgg ccggcgtctg cctcatcggc tgggacgagc cgcacgagtt
    19081 ccgccccgac gaacgggccc tgctcaccgc cttcgccgga ctcgccggac aggccctgac
    19141 gcgtgcccgt gccttcgacg cggagcacga actcgtcggc atgctccagc gccagctgct
    19201 cccgcgccgc ctgcccgaac tccccggcgg cgtggccgtc gcccgctatc tcccggccac
    19261 cgcgggcctg gaggtgggcg gcgactggta cgacgtcatc ccgctcccgg accaccatgt
    19321 cgccctcgtc atcggcgacg tccaggggca cagcgccgcc gccgcgaccc tcatgggcca
    19381 gatgcgcacg gcgctgcgcg cctacgcggc cgagggccac ccgccggacg tcgtggtctc
    19441 ccatgccaac cggctcctga tggaactgga gaccgacctc ttcgtcacct gctgctatgt
    19501 cgacgtcgac atggaggagg gcaccgcctg gtgcgtccgg gccggacacc cgccccccgt
    19561 cctgcgccac ccggacggct cgaccgagat cgccgaggcc gacgggggtc cgcccctcgg
    19621 cgtcgtcacc cgggccgagt tcccgatgac cccgctgcgc ctggtccccg gcgccgtcgt
    19681 cgtcctgacc acggacggcc tcgtggagtc cgccggcctg gacatcgaca ccggtctcga
    19741 ccgcctcgcc cgcgccgcgt ccgccgccga ccccgcccac ctcggcctcg tcgccgacac
    19801 cctgctcggc ggcgcccacc gcggcgacga cgtggccctc ctgctgatgc gctacgacgg
    19861 catggccgtc aaacccctgc gcgagggctg gaccgtgtgg cgggtgcccg aggcggcccg
    19921 ccaggcccgg cgcttcaccc ggcgcacgct gcgcgcctgg ggtgtgtcgg cgcacaccct
    19981 ggacgccgcc ctgctcgtcg tgtccgaact ggtcaccaac gccctggtgc acaccgacgg
    20041 ccgggtccgc ctcgacctca ccctcgtcaa ccaccggctg cgggtcgccg tcaccgacac
    20101 ctcgccccgc agcccggtca agccggccag cctcggctgg gaggccaccg gcggccgggg
    20161 catcctcctg gtggaggcgg tgtcgcaggc ctgggggacc gtgccggtca gcggcggcaa
    20221 gcaggtgtgg agcgagctga cgccgaccgg ctgagccgtc ggaaccccac gtgtcccgcg
    20281 gcacggacgg ggtacccggc gcccatggac accttcgcct ccgtcttcgt cgcggcatcc
    20341 ggaaggtccg cgctggccac cgtcgccttc atcgccgtcg ggctcgtcct cgtcggcggt
    20401 ctgatctggg cgttccggct cggtttcaag gtccgcagcc gcgagcccgc gcccccggcg
    20461 ccgcacgaac agccccgcag gcccgggacc gccccggccc acgagaccca ccgcacccgc
    20521 gaacccaacg cgatgcccga gcccacggac ggcgaacgcc tcaccccgca ccaactgcgg
    20581 cccaccggca gccgggacag cgccgaccag cgccgccccc gctgggagga gggctccggc
    20641 ggctgattcg gcagcgcagg ccccggtgcc ggctgaacca ggggcacaag ccctgtgacc
    20701 gagaaggatg atgaaccgtc gtgaccgcgc acaccgagga gcaaccggtg atcctccggg
    20761 ccgagaccgg ctgggccagg gcccgccgga tccgccgcca gtcgaccgcg ctgcgcacgt
    20821 gcctgcccgc cgtcgccgcc gcaccttccg cgacggccgg gatgcagacc ggcgcggaat
    20881 ggaacattgt caggggtgag gactgaccgg cagacagtgc gcacgagcgg atgaatcggt
    20941 cgcggccggg cgaccggggc tggagtgacc ccgatgaagg ctctcgtgct gtccggcggc
    21001 gccgggaccc gcctgcggcc gatcacccac acctcggcca aacagctcgt gccggtggcc
    21061 aacaaggccg tcctcttcta cggcctggag tccatcgccg ccgccggtgt caccgaggtc
    21121 ggggtcatcg tgggcgacac ggcggcggag atccgcgaag ccgtcggcga cggctcccgc
    21181 ttcggcctcg acgtcaccta catcccgcag gacaggccgc tcggcctggc ccacgcggtg
    21241 atcgtcgcgc gggacttcct cggcgacgac gacttcgtga tgtacctggg cgacaacttc
    21301 atcgtcggcg gcatcaccga cctcgtcgac gagttccgcc ggacccgccc cgacgcccag
    21361 atcctcctca cccgcgtccg tgacccccgc gccttcggcg tggccgagct ggaccccgcc
    21421 ggacaggtcg tcggcctgga ggagaagccc gcgcacccca ggagcgacct cgcgctggtc
    21481 ggcgtctacc tcttcacccc cgcgatccac gacgccgtcc gcgccgtccg gccgtccgga
    21541 cgcggtgagc tggagatcac cgacgccctc cagcagctga tcgacaccgg cgcccgggtg
    21601 cgctccacga tcatcaaggg ctactggaag gacaccggca acgtcgtcga catgctggag
    21661 gtcaaccgga ccgtgctgga gggcgtcgag cggcgcatcg agggcgaggt cgacgactcc
    21721 tccgagaccg tcggccgggt cgtcgtggag gcgggcgccc gcgtggtgaa ctcgcgtctg
    21781 gtcggaccgg tcctgctggg cgcgggcagc gaggtccgcg actcctacat cggccccttc
    21841 acctccgtcg gcgagaactg ccggatcacc gacagcgagc tggagttctc catcgtgctg
    21901 cgcgactcct ccatcgaagg cgtgggccgc atcgagaact cgctgatcgg ccggcacgtc
    21961 gaggtcaccc cggcgaccgg ggtgtccagc gcccaccggc tggtgctcgg cgaccacagc
    22021 aaggtacaga tccacccatg aacctcctcg tcaccggggc cgccggattc atcggctcgg
    22081 cgtacgtgcg cggcctgctg gcccgcgacc cggccgtccg cgtcaccgtc ctggacaagc
    22141 tcacctacgc cggaaacccc gccaacctgc ccaccggcca cccccgcctg gagttcacgc
    22201 acggcgacat ctgcgacgcc gacctcgtgg accgggtgac ggccggcgcc gaccaggtcg
    22261 tccacttcgc ggccgagtcc cacgtcgacc gctccatcga cggcgcgggc gccttcgtgc
    22321 gcaccaacgt cctcggcacc cagacgctcc tggacgcggc cctgcggcac ggcgtcggtc
    22381 ccttcgtgca cgtctccacc gacgaggtct acggctccat cgagaccggc gcctggaccg
    22441 aggagcagcc gctgagcccc aactcgccgt acgccgcctc caaggcgtcc tccgacctga
    22501 tcgccctcgc ccaccaccgc acccacggcc tggacgtccg cgtcacccgc tgctccaaca
    22561 actacggccc gcgccagtac cccgagaagg tgatcccgct cttcgtcacg aacctcctgg
    22621 acggcgagca ggtccccctg tacggcgacg gacgccacgt ccgcgactgg ctgcacgtcg
    22681 aggaccactg ccggggcgtc gacctcgtgc gcacgaaggg ccgccccggc gaggtgtaca
    22741 acctgggcgg cggcacccag ctgagcaacc gcgagctgac cggtctgctc ctcgacgcct
    22801 gcggggcggg ctgggaccgg gtccggcacg tcgaggaccg caagggccac gacctgcgct
    22861 actgcgtcga ctggacgaag gcccgcgacg agctcggcta ccggccccgg cacgacttca
    22921 ccgccggtct cgccgggacg gtcgcctggt accgcgacca ccgcgactgg tgggaacccc
    22981 tgcgcccgca agcgcgcacg ccgtgaggtg gctggtcgcg ggcgccggcg ggatgctcgg
    23041 ccgggacacc gtgcaggagc tgctgcggcg cggcgaggac gtgaccggcc tcgaccgcac
    23101 cgccctcgac gtcacccggc ccacgtcggt ggccgcggcg ttcggcgcgc accggcccga
    23161 cgtggtcgtc aactgcgccg cccacacggc cgtcgacgac gccgagaccg acgacgcacg
    23221 cgcgctgctg gtcaacggcg agggaccccg cctgctcgcc gccgcctgcg ccgcgcacgg
    23281 cgcccgactg gtccacgtat ccaccgacta cgtcttcgac ggcacggccc gcacccccta
    23341 cgcggaggac catccgccgt ccccccggac cgcctacggc cgcaccaaac tggccggcga
    23401 acgggccgtc cgcgccgtgc tccccgacgc ctcggtcatc gtgcgcaccg cctggctcta
    23461 cggcgtccac ggccgcagct tcgtgcgcac gatgctcgac ctggaggccc gccgcgacac
    23521 cgtcgacgtc gtcgacgacc agcgcggtca gcccacctgg agcgccgacg tcgccgtgcg
    23581 cgtcgccgac ctcgggccgc tggccgggcg cggcgcgagc ggcgtcttcc acgccaccgc
    23641 ggccggcgag gccacctggt acgacctggc ccgcgaggtg ttccggctga ccggcgccga
    23701 cccggaccgg gtgcgccccg tcacgggcga ccaccacccc cgtccggcgc cccgcccggc
    23761 ctacagcgtg ctgtcgcacg gccggtggcg cgaggccggc ctgccgccgc cgcgggactg
    23821 gcgcacggcg ctgcgacagg cgctcccgct gatccgcggg gcgtcccccg aaccggtgcc
    23881 gtccgaggag cccgaggagt cccttcgtga aacgccatga gttcctgcgg gagctgcaca
    23941 aggtcaccgc caaccgcaac tacctggaga tcggtgtcaa cgacggccgc agtctgcggc
    24001 tgtcccgcgt cccgagcatc gcggtcgacc ccgcgttcaa ggtgacctcg gagctgcgct
    24061 gcgacgtgca cctggtgagg gccaccagcg acgacttctt cgcccgccgc gaccccctcg
    24121 cccatctcag gggcggccgc cacccgctgc gcaatctggc ccggggccgc catcccctcg
    24181 gccactggcg ccgcgccacc ctcgacctgg ccttcatcga cggcatgcac ctgttcgagt
    24241 tcgcgctgcg cgacttcatc aacgtcgagc ggcactgcga ctggtcgagc gtgatcgtcc
    24301 tggacgacat gctgccccgg ggcgtcgacg aggccgcccg cgaccggcac accaccgcct
    24361 ggaccggcga cgtctacaag ctcaccgaga tcctgtcccg ccaccgcccc gacctggtga
    24421 tcgtgccggt cgacaccgag cccaccggac agctcgtggt cttcggcgcc gacccccgca
    24481 acccggtgct gcgccggcgg taccacgaga tcgtcgccga gtacgaggtc cccgacccgc
    24541 agaaggtccc cgaggacgtc ctggaacggg tgcgcgcggt acggcccggg acgctgctgc
    24601 gggcgggttt ctggaagccc ctggtgcggg cccgcaaccg gggcctggac cgctcccggg
    24661 gctgggagcc gctgcgcggg gcgctggagc gggcggccgt cagccgctga ggcgcagcgc
    24721 gcggtagtgg tcccggcagg aggcgtacga gggcagcagc cccgaggccc gcgcctcggc
    24781 cagcgacggc gccgccgcgt ccctcggcga cagcaccggc tccaccccgc gcggccagtc
    24841 gatgcccagg ccggggtcga gcgggtgcac gccgtgctcc cgctcgggcg cgtatccggt
    24901 cgagcacagg tagacgacgg tggcctcgtc cccgagggcc aggaaggcgt gtccgaggcc
    24961 ctcggcgagg aacaccgcgt gccgggtgac gtcgtccagc cggaccgcct cccaccggcc
    25021 gaacccgggc gagcccaccc gcagatcgac gaccacgtcc agcaccgcgc cccgcacaca
    25081 ggtcacgtac ttggcctgac ccggcgggac gtccgagaag tggacgccgc gcaggacgcc
    25141 ccggcgcgag acggagcagt tcgcctgggc gagccccaga ccgtggccgg tggccgcgcg
    25201 gaactccggc tcgcggaacc actcgtggaa gctgccccgc ccgtcgggca ggacccgcgg
    25261 ctccagcacc caggcgccct cgatccccag cggccgcatc gcgtcacttc ctccgtgccg
    25321 tgatccggcc gagcgcccgg taggcggcgc gtcgcatcct gcgggccagt cttcgcgcgc
    25381 cgccgggctg cggcgccgga acgacgagga caccgtccgc gtccacgtgc agcgcgaagg
    25441 gcagcgggtg gaagcgcgcc ccgtcggcgt ccggggtgag gcacaccgtc gtcagccagg
    25501 tgcggcccgt caggtcggcg acgggcaggg ccgccgccat ccggccgccc ggggagagcg
    25561 tcccgaagac ctcgcgggag ccgccggact tcgccgccgt cagccgcagc agcacgccgg
    25621 cggcctcggg gacgtgcagc ggcaggacca cgtgcagccg ttccccggtg acggtgacgt
    25681 ccccggccgc cacccggccg agccccagcc ggttgcccgc gtggccgacg tccagcgcga
    25741 gactcgcgta ccggtcggtc cagtacggca gcaccacgcg ccccgctacc accgcggcgg
    25801 gcggggcggg tcggccgtgc cggtgcgccg ggccgagccg cagctccttg gtccagccgc
    25861 ccaggccgag gcgcacgaac acgtcccaca ggccctcgcc cgccgggccg ccgctcagcg
    25921 ccgaggccgg atcgacggtg gcggtcgcgc gcagcacgag ccgcaccagg ctgccgtcgc
    25981 cgcccgccgg caccgtctcg cggaccacgt ccaccggctg gaagtactgc gccgcgccga
    26041 cccgttcccg cagcagcagg tcgggcaccg cccggtcgaa ccggcccacg atgtccgtgc
    26101 ccagccagcg caccgcctcg gcgacgtcgt gcggcggcca ttgcggggag cccccggcgg
    26161 acgggaacgt catcggagcg ccgtcgtgcg tcagctcggc ggcgaacgtg atccgcagcg
    26221 tgccgccccg ccactcgacg tcctcggggt cgacggcgag cgcgacgccc gcctcccact
    26281 gcgcgaaggc gacgacgtcg tcgtagcgcc cctcggcggc cagcgcggcc acgacccgct
    26341 gggcgggctg gagcggcgcc gccacccccg gcccgaaccg ttcgacgacg accgagtgga
    26401 tctcgtcgaa caggtgcctg cggtagtcct cgggcaggcc gaggaagcgc cggccgcgca
    26461 gccgctcgac catctccacg cgcagccacc gccggaacag ccggtcgcgc agcgggcccg
    26521 gctcggtgta ccgctcgacg acgtcgaggg cctcccgcag gttcttgaag taccccaccg
    26581 ggtcgaaccg ctggaggccc gcgttcgcgg cgtcgtcgcg ccggacgtgg tagtagcaga
    26641 cgtagtcgct gagcacggac acgttgccgg cccgcagata ggcctcggtc acgaagacgt
    26701 ggtcctccag ccgccgccgt ccctcgggga agcgcaggcc ggtgcggtcc aggaacgccc
    26761 ggcggaccat cttgtgcggg gtgaggctgt cgatcagcgg cgcgttcgcg acggtggcgt
    26821 gcgggcggtt caggcggaac agctccaccg gcaccgagcg ccccttgccg gccatcttgc
    26881 ccacgacgac gtcggcgtcg ttcgcgaccc cgtaggcgta catccgctcc agggcctcgt
    26941 cgccgaggtg gtcgtcgtcg tcgacgaaca tgacgtactc gccgcgggag aggtcgatgc
    27001 cgacgttgcg gggcttgccg gcccagccgg agttctcctg gtggacgaca cggatccggc
    27061 cgtcgtcggc ggcggccgcg tccagccggg ccggggtggc gtcggtggag ccgtcgtcga
    27121 cgaagatcac ttcgtactcg tccggcggga gcgactgccg cagcagcgag gcgaggcact
    27181 cctcgatgta gggaccgggg ttgtggacgg ggacgatgac gctgaccttg accggcatcg
    27241 ggctcctggc cccctagctg gatcacttgc cgtgcgcggg acggcgggtg cgcacggccc
    27301 gatgctaacc ccgccaccgg cgccccacct gtccggattc gcccgggtcc gggttttgta
    27361 ctctggcgcg gtgcgtcttc tgatgatggc cgacacccac ctccccaagc gcgccaaggc
    27421 actgcccggg ccgctgctcg acgagctccc gctcgcggac gtggtgatcc acgcggggga
    27481 ctgggtcgac acggagaccc tcgacctgct ggagagccgg agccgccggg tcctcggcgt
    27541 gtacggcaac aacgacggac ccgccctgcg cgcccggctg cc
//
