LOCUS       NZ_BMSI01000007        22205 bp    DNA     linear   CON 02-AUG-2024
DEFINITION  Streptomyces asoensis strain JCM 4185 sequence07, whole genome
            shotgun sequence.
ACCESSION   NZ_BMSI01000007
VERSION     NZ_BMSI01000007.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces asoensis
  ORGANISM  Streptomyces asoensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 419478)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014649075.1-RS_2024_08_02
            Annotation Date                   :: 08/02/2024 04:45:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,813
            CDSs (total)                      :: 7,736
            Genes (coding)                    :: 7,563
            CDSs (with protein)               :: 7,563
            Genes (RNA)                       :: 77
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 53 of 173
            Pseudo Genes (incomplete)         :: 140 of 173
            Pseudo Genes (internal stop)      :: 10 of 173
            Pseudo Genes (multiple problems)  :: 28 of 173
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:21:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 112336
            Orig. end                         :: 134541
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMSI01000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22205
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22205
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22205
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12205](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12205
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(257..1273)
                     /locus_tag="IE189_RS18675"
                     /old_locus_tag="GCM10010496_38180"
     CDS             complement(257..1273)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010034184.1"
                     /locus_tag="IE189_RS18675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_38180"
                     /product="substrate-binding domain-containing protein"
                     /protein_id="WP_189923030.1"
                     /transl_table=11
                     /translation="MNTPLPARSADGPHGSVRRTALTAVCCLLLLTGCSGATASGSEGK
                     AADGPGDRLKVALVTHGAKGDDFWELVRKGAEAAAAKDGVDLTYASDSDAGGQAELVRD
                     AIADRVDGIAVTLAKPQAMKSPVARARAAGIPVVGLNSGIDAWRSAGLVEYFGQDESVA
                     GRAVGDKLDGLGAKHALCVIHERGNIALEARCAGVKKTFTGETEMLYVDGTDMDAVTTT
                     VAARLRQEPDIDEVITNGAQFALAAVKAADQADSGAKVATFDLNKDLVTAVREGSVQFA
                     VDQQPYLQGYLAVDALWLYKTNGNLSGGGVAPVLTGPAFVTKTNVAEVARFAAAGTR"
     misc_feature    complement(1492..1510)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.72"
                     /tool="antismash"
     gene            complement(1883..2341)
                     /locus_tag="IE189_RS18680"
                     /old_locus_tag="GCM10010496_38200"
     CDS             complement(1883..2341)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125290.1"
                     /locus_tag="IE189_RS18680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_38200"
                     /product="DUF6114 domain-containing protein"
                     /protein_id="WP_189923031.1"
                     /transl_table=11
                     /translation="MTFTQWRDRFRVWRGHRPFAGGVLLVLGGAEILVTMKAPLPVILH
                     VGMQGLAGYLLPSLMVVCGLLILFNPTQRLFYSIIAILLSLGTWLTSNIGGFVVGLLLG
                     AVGSSISFGWLPDQEPRKSRRQERKEARTETHAESVRKDGFSGAGEPA"
     gene            complement(2341..3006)
                     /locus_tag="IE189_RS18685"
                     /old_locus_tag="GCM10010496_38210"
     CDS             complement(2341..3006)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125291.1"
                     /locus_tag="IE189_RS18685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_38210"
                     /product="DUF6230 family protein"
                     /protein_id="WP_189923385.1"
                     /transl_table=11
                     /translation="MASSPDVTSSADNTPENPESGSAERRGRVRLRRAAVMAVPATFVA
                     AGLAVLTAQGALGVQFAISGMPFVVTADRLDGEGFAQFGGLDNMIENSPNQGDTGGQVL
                     VVTSVVKNGKITNMCQSVDLGGIQLILRAGAGSTPVSVKNLAIDSDEISGDAEFNNIEI
                     GRDSSTFDKVPIQGPAGVYGQQADTVVIKNLYQHNYAATAAVFKLPGLKMSFSSEGCK"
     misc_feature    complement(3162..3177)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.78"
                     /tool="antismash"
     misc_feature    3191..3209
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.31"
                     /tool="antismash"
     misc_feature    3192..3207
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.53"
                     /tool="antismash"
     misc_feature    3270..3285
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 16.91"
                     /tool="antismash"
     misc_feature    complement(3298..3313)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.12"
                     /tool="antismash"
     gene            3682..4317
                     /locus_tag="IE189_RS18690"
                     /old_locus_tag="GCM10010496_38220"
     CDS             3682..4317
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675693.1"
                     /locus_tag="IE189_RS18690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_38220"
                     /product="Tat pathway signal sequence domain protein"
                     /protein_id="WP_189923033.1"
                     /transl_table=11
                     /translation="MRTRSLLALAGTVAALSLTAVTPASAAGAVLTTANGDVAVGDVLN
                     ASLASGTTATLYSSATGTSGVSCASSGFSATVTDNPTAPGTATESLTAHTFGSCTANVI
                     GVLGVTSVTVNNLPYTTSVSSGGTVTVTPASGSTIQTTVVLRTLLGSINCVYQAPSLTG
                     TANNADNSINFASQQFTKTSGSSLCFANGYFTAKYSPVTDAGAAVTVN"
     gene            complement(4394..5344)
                     /locus_tag="IE189_RS18695"
                     /old_locus_tag="GCM10010496_38230"
     CDS             complement(4394..5344)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125293.1"
                     /locus_tag="IE189_RS18695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_38230"
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="WP_189923035.1"
                     /transl_table=11
                     /translation="MPRTTAHRTAALATAALSPLLLGLWAAAPAQAHGAPTDPVSRVYA
                     CSPEGGADARTAACRAAIAANGTSFAAWDNLRVADVNGRDRQTVPDGRLCSGGLPAYKG
                     LDLARADWPSTRLTPGGTLRMTYASTIAHTGTFKLYLTKPGYDPTKPLTWSDLPASPFA
                     EVEDPPLTNGAYRFTAKLPADRTGRQMLYTIWQNTSTPDTYYSCSDVVFPAAAASKGEP
                     KSGATTKTPAAARPTASTSVASASTTPASPSAAPSASTVSAAAPAEAAAGPDSTPVASV
                     SGGGSGPSAPVLAGGAAAVLVLTGGAALVARLRRR"
     gene            5683..7503
                     /locus_tag="IE189_RS18700"
                     /old_locus_tag="GCM10010496_38240"
     CDS             5683..7503
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020122073.1"
                     /locus_tag="IE189_RS18700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_38240"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_189923036.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 1.3e-50, bitscore:
                     166.7, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTSPALRRKLISVAASSAALLTAASTASAVAAQEPVPAGSAHPT
                     AQISAATEAAPGVPAERLIVGYKSGAAEAKSNPAAEADAAAKGRASGEDVDFRRRLGTG
                     AALVGLGDGLSAADVADVVDRYRADPEVAYVVPDRLNKPKADPNDTEYAKQWDLYETTA
                     GMNVPGAWPTSTGTGVTVAVIDTGYVAHSDLAANIVGGYDFIADTAVSVDGDGRDANPA
                     DPGDHYAANECGSGIPASNSSWHGTHVAGTIAAVTGNGKGVAGIAYGAKISPVRVLGKC
                     GGYDSDIIDAITWASGGTVSGVPANADVAKVINMSLGGDGACTSATQTAITAAVNRGTT
                     VVVAAGNENDNVANHSPGNCNNVISVAATNRTGARASYSNYGSLVDISAPGGQTSTGTA
                     NGILSTLNSGTKAPSAESYAYYQGTSMATPHIAGLVALVKSANPALTPAQIEAAVKANA
                     RALPGACSGGCGAGLADAARTVQAVSGSGGSTAGTTYASTTALSIPDNGAAVESPITVG
                     GRTGNAPSALQVGVDITHTYRGDLVIDLVAPDGTAYRLKAASSSDSADNVTTTYTVDAS
                     GESANGTWKLRVQDTAAQDTGRLNGWKLTF"
     gene            7933..8583
                     /locus_tag="IE189_RS18705"
                     /old_locus_tag="GCM10010496_38250"
     CDS             7933..8583
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125295.1"
                     /locus_tag="IE189_RS18705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_38250"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_189923038.1"
                     /transl_table=11
                     /translation="MARQLRAEQTRTTIITAAADLFDRHGYESTSLSDIVAHAHVTKGA
                     LYFHFAAKEDLAHAIMELQSSASRRIAGEIDDRGYASLEALIRLTFALTRLSVEGPIAR
                     AGLRLATGGVPVRPPLPHPFVELTDLISRRLGGALKESDIHQDVDIDAVAHSLVCFFVG
                     TRVVGRTREPAGRLPRRMAEMWHVLIRGLVPVPRRPRYLSLAARLEREIMPAV"
     misc_feature    7945..7947
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            8656..9843
                     /locus_tag="IE189_RS18710"
                     /old_locus_tag="GCM10010496_38260"
     CDS             8656..9843
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125296.1"
                     /locus_tag="IE189_RS18710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_38260"
                     /product="damage-control phosphatase ARMT1 family protein"
                     /protein_id="WP_189923040.1"
                     /transl_table=11
                     /translation="MSDTPAPPVILGDEPGSFPHSVLAERHPAIIRQVREAFPYGPDVH
                     RRLDALRESCAEGVVEALPDTAPDRDRWRDWGLDAYVGRSWFDVPWLWSESYFYRQLLE
                     AVGYFGTGPWRGIDPFRPFKLAELDAPETDAELAALDGLGARPAGERDRALLHGSLWGN
                     RADLGFRLSDAQAQERAAVPALVADDSDTFWSLLPAGDTARTRTLCLVADNSGRELIPD
                     LLLAAHLLAQGRCGRVVLHVKPYPYYVSDATTADVVDALRKLTGAPGAAADHGRRLWTA
                     MAEGTLTIRAHPFSAAPLPCTAMPADLRAEFAQAALTVVKGDLNYRRLVGDSRWPPTTP
                     FADVTAYFPGPVAALRTLKSDVITGLDAGTEAALVAAEGLRWRTGGTHALIQVRE"
     gene            10001..12205
                     /gene="cyc2"
                     /locus_tag="IE189_RS18715"
                     /old_locus_tag="GCM10010496_38270"
     CDS             10001..12205
                     /EC_number="4.1.99.16"
                     /EC_number="4.2.3.22"
                     /EC_number="4.2.3.75"
                     /codon_start=1
                     /gene="cyc2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125297.1"
                     /locus_tag="IE189_RS18715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_38270"
                     /product="germacradienol/geosmin synthase Cyc2"
                     /protein_id="WP_189923042.1"
                     /sec_met_domain="T1TS (E-value: 1.3e-79, bitscore: 262.9,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQPFELPHFYMPHPARLNPHLEQARTHSTRWARDMGMLEGSGIW
                     EQADLEAHDYGLLCAYTHPDCDGPALSLITDWYVWVFFFDDHFLDMFKRTPDRAAGKAH
                     LDRLPLFMPLDLSTPVPEPRNPVEAGLKDLWERTVPHMSQDWRRRFAVATEHLLNESLW
                     ELSNIDEGRIANPVEYIEMRRKVGGAPWSAGLVEYATAEVPAAVAGSRPLRVLMETFSD
                     AVHLRNDLFSYQREVEDEGENSNGVLVLETFFGCTTQEAADTVNDILTSRLHQFEHTAF
                     TEVPAVALEKGLTPGEVLAVAAYAKGLQDWQSGGHEWHLRSSRYMNQGAVSGTPWSKPT
                     GPGTSAADLGALLAPAVVAGALPGQRGRLRAYAHVPFRKVGPSLLPDFHMPYEVRLSPH
                     LEACRPRLTAWSHRMGILREGVWDEDKLAAFDLPLCSAGLDPDATPEALDLSAQWLAWG
                     TYGDDYYPLVYGNRRDLAAARLTTARLSACMPLDGEEASVVPVNGMERGLADLWARTTA
                     DMTADERRTLRAAIDAMTESWVWELSNQLQNRVPDPVDYLEMRRATFGSELTLSLCRMG
                     RGPAVPPEVGTSGPVAALENAAMDYACLTNDVFSYQKEIEYEGEMHNAILVVQNFFGCD
                     YPAALGVVHDLMTQRMQQFEHIVAHELPVLYDDFDLCAEARAAMGRYVEDLQNWLSGIL
                     NWHREVDRYKPAYLARRTHGFLPDLAPAAPLPHLSAAGLR"
     gene            12281..12901
                     /locus_tag="IE189_RS18720"
                     /old_locus_tag="GCM10010496_38280"
     CDS             12281..12901
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007445378.1"
                     /locus_tag="IE189_RS18720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_38280"
                     /product="PDZ domain-containing protein"
                     /protein_id="WP_189923044.1"
                     /transl_table=11
                     /translation="MEQTALRPKPLPGSEPGGGRPDTGARGRPPRTARRRGKRLATLLL
                     GVSAGTVLVLSGVGLATVGTTVLGLSAPAGFQRQAVPGASGTGPAPGRPVPAAPSGASR
                     PPGWSEASAATPRPPGAPLGLEAVDAEGPGARIVAVHVPGPGYRAGLVRGDVLLTFGGH
                     RIRSATDLARAVDEARPGRAIELTVRHRDGREAALTALPGVVT"
     gene            13405..14532
                     /locus_tag="IE189_RS18725"
                     /old_locus_tag="GCM10010496_38290"
     CDS             13405..14532
                     /EC_number="3.4.11.9"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172: methionine aminopeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996926.1"
                     /locus_tag="IE189_RS18725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_38290"
                     /product="aminopeptidase P family protein"
                     /protein_id="WP_189923046.1"
                     /transl_table=11
                     /translation="MTGTAPAPFTADDYRARMQRAAREAADAGLAGLLVAPGPDLVWLT
                     GYAPTAVTERLTMLVLAPGRDPVLVVPTLEAPDAAKAAGASALTLRDWTDGKDPYAATA
                     ALLDTDGRFGISDGAWAMHLLALQRALPATSYASLTDALPMLRAVKDAAELELMAAAGA
                     AADAAFEEIRRVPFGGRREKEVGADLADLLRRFGHSQVDFTIVASGPNGANPHHEVGDR
                     VIRDGDMVVLDFGGLKDGYGSDTSRTVHVGEPTEEERRVHDLVREAQEAGFRAVRPGVE
                     CQEVDRAARAVITDAGYGEYFIHRTGHGIGVTTHEPPYMIEGEERPLEPGMCFSVEPGV
                     YLPDRFGVRIEDIVTVTEDGGRRLNDTTRELVIVG"
     gene            14582..15553
                     /locus_tag="IE189_RS18730"
                     /old_locus_tag="GCM10010496_38300"
     CDS             14582..15553
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996925.1"
                     /locus_tag="IE189_RS18730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_38300"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_189923048.1"
                     /sec_met_domain="APH (E-value: 7.2e-19, bitscore: 63.0,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQAPTPTADTVRRLVRALLEEGGTAGGPGPEVRPVAPGGTPATW
                     WVGARHVLRLATDRETTLRRARELRLRDLVRPHVPVAVPTSVAHGEWSPGLVYTLDTKL
                     PGGTAEEHDVSAVGEADLAGLLRGLREVPPRQAETLGVPRVAPRSLEALRRMAVAVAER
                     LARADEFDPTRLHQLTPPGAAQLAAQPGSAVLVHHALRGEHLVVSADGRVRGVLDWTGA
                     VLGDPAEDIAGLALAVGSGAAVRAATLAGYGARPCLRGLWLARCDTVLRLAEGLDARTA
                     GPRDAEALALPRTRLGRAWEAILLERVTEFREEGEDGPDEKV"
     gene            complement(15632..17377)
                     /gene="treZ"
                     /locus_tag="IE189_RS18735"
                     /old_locus_tag="GCM10010496_38310"
     CDS             complement(15632..17377)
                     /EC_number="3.2.1.141"
                     /GO_function="GO:0033942 -
                     4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0005992 - trehalose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="treZ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CBM_48"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1297: Pullulanase, type I"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010034231.1"
                     /locus_tag="IE189_RS18735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_38310"
                     /product="malto-oligosyltrehalose trehalohydrolase"
                     /protein_id="WP_189923050.1"
                     /sec_met_domain="CBM_48 (E-value: 7.8e-07, bitscore: 23.7,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="Alpha-amylase (E-value: 1.8e-12, bitscore:
                     41.9, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQFEVWAPQAERVTLRCDRTTRALERDPERAGWWTGEAEAADGSR
                     YGFAVDDGPVRPDPRSRRQPDGPDGLSAVVDHARYEWRTRWSGRPLPGAVLYELHVGTY
                     TPEGTLDAAAQRLGHLAELGVTHVELMPLCAFPGRHGWGYDGVAPWAVHEPYGGPEALK
                     RFVDRAHELGLGVVLDVVHNHLGPSGNYLPVFGPYFTETHHTPWGAAINLDAPGSDEVR
                     AYLVGSALAWLRDYRLDGLRLDAVHALADTRACHFLEELSAAVDALAADTGRPLFLIAE
                     SDLNDPRLITPRRDGGLGLHAQWNDDFHHALHTALTGESQGYYADFARAPFAALAKTLT
                     GGFFHDGTYSGFRGRGHGRPLDRARLPAHRLLGYSQTHDQIGNRAQGDRLSASLSPGLL
                     ACAAALTLTAPFTPMLFMGEEWAAGTPWQYFTDHTDPELAEAVRRGRRREFAAHGWAEE
                     DVPDPQDPATRERSCLDWSEPEREPHARVLAWYRELIALRHTTADLTDPDLADIKIAHD
                     PEARWLAFRRGDVRVAVNLGKETAAIPLGPRPARVLATWEPVDVPGRDGLLHVPGESCV
                     VLEQQ"
     gene            17543..18094
                     /locus_tag="IE189_RS18740"
                     /old_locus_tag="GCM10010496_38320"
     CDS             17543..18094
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385491.1"
                     /locus_tag="IE189_RS18740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_38320"
                     /product="DUF1707 and FHA domain-containing protein"
                     /protein_id="WP_189923052.1"
                     /transl_table=11
                     /translation="MTSSFEFNTYPARLSDVERDRALKVLRDGVAMGRLSHDTFIRRME
                     LALVARRSDELAVLTADLPRENRFSRVVFGTVEAVSGFTVRVRRAWQAERLPKLLLPHP
                     GTRHALRIGRDPASGLRLTHESVSRVHAELARQGGMWILRDLGSTNGTTVNGRRVIGAA
                     VVREGDQVAFGRMAFRLSTN"
     gene            18287..19615
                     /locus_tag="IE189_RS18745"
                     /old_locus_tag="GCM10010496_38330"
     CDS             18287..19615
                     /GO_function="GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125306.1"
                     /locus_tag="IE189_RS18745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_38330"
                     /product="M14 family zinc carboxypeptidase"
                     /protein_id="WP_189923054.1"
                     /transl_table=11
                     /translation="MDEVAARAAVLAVRGSGDARLRRVGVSRAGSPLWLLSLGRGARQV
                     LVVAGPHANEPVGGATVLRLAERVLADPRLTVGADATWNLLLCLDPDGLRRNEGWLTGP
                     YTLGRYFRHFFRPGFLEQPEWLPDGAARAALPETRALLRLQDELRPFLQCSLHGVDVGG
                     AFVELTRDLPGLSRRVAHTAARLGIPRELGPFDTLHWPRLGPAVYRIPPPRPGDLAAAI
                     TEAAVESTWYHPHRYGTVTAVVEAPMWGVAAAEDDSRPADRDAVLRAVSGALRHDAQLL
                     ERILTRVRPHLAATAEAARLLAPVGDHLLVCPALADAWDPATADPRRPLPPLSTAHLTA
                     LRIAGRRIAVRTAGLLHQLVAGSGRDPAGALPELDGLIDAWCAGYQDECGARWIPVARQ
                     AEYQARIVLAAFELAGRAPAEPARARSGESDWGSHPAVPMHRE"
     gene            19612..20067
                     /locus_tag="IE189_RS18750"
                     /old_locus_tag="GCM10010496_38340"
     CDS             19612..20067
                     /GO_function="GO:0004867 - serine-type endopeptidase
                     inhibitor activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125307.1"
                     /locus_tag="IE189_RS18750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_38340"
                     /product="SSI family serine proteinase inhibitor"
                     /protein_id="WP_189923056.1"
                     /transl_table=11
                     /translation="MTYFLTCLRSAKAVRRALPAAAALLLAAGAAPAQAVSRDGLSGNW
                     LQLTVTRGDARSSDTRGTLLLCDPPQGHSRAAEACDVLTRADGDVGALHGDSGRVCALV
                     YAPVTVRAQGEWNGRPVDYRHTFSNDCEREALTGAVFALDDQEVPEV"
     gene            complement(20180..21430)
                     /locus_tag="IE189_RS18755"
                     /old_locus_tag="GCM10010496_38350"
     CDS             complement(20180..21430)
                     /GO_function="GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675708.1"
                     /locus_tag="IE189_RS18755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_38350"
                     /product="M14 family zinc carboxypeptidase"
                     /protein_id="WP_189923058.1"
                     /transl_table=11
                     /translation="MSLLPELRYPTVTELISSARALAAYRPGLCVLRQVGVSRAGRPLN
                     LLSVGRARRAVLVVAGAHANEPTGGSTLLALAERVVQERELRDGTSWHFLLCADPDGAS
                     LHVTPAPRSLLEYHLGFFRPAGPEQPEWSPAVLPPDRLPPETRALTRVIDELRPYLQVT
                     LHGTDLGGSWVQLTKDIPGLAEPFAKSAAQLHIPVETGASDAAGWPASGPGVHVMPAAG
                     AEAAYPSMPDDARHSTWYHAHRYGGLTAVVEVPMWASDMVDDPAQHPAPAAAIRRLARR
                     LLRDTTEVERVLVEALPRLEGVDGPLLRAAKWALELVPGLAADWTDTPPADTTMAYVGS
                     VDAFARRLPLRAAAMLWRVLQECDDHAAPRLEHLVETWSDAFAYRFRARWVPLEHQVEH
                     QSRTVVAAALHARERAA"
ORIGIN
        1 gtcgcctcgg tgcccatggc tccggtcgag cggctcagtc cggtctgcgc gcgcagccgg
       61 agaccctcct cgaacatctg ggtcgtcgtc acaccccaca tggcggcgag ggtgacgccg
      121 ggcaccagtg ccagcaggat gagggagaga cgtatggagc cgagtcggcg gcgccgggca
      181 cctgtccgtg cagacatggt cgtcctaggg cgatgagcga gggggagggg ggctgggcgg
      241 ggcggagccg gtccgctcag cgggttccgg ctgcggcgaa gcgggcgacc tcggcgacgt
      301 tggtcttcgt gacgaaggcc ggacccgtca gcacgggtgc cacaccgccg ccgctgaggt
      361 tgccgttggt cttgtagagc cagagggcgt cgacggccag atagccctgg agatagggct
      421 gttggtccac ggcgaactgg acgctgccct cgcggacggc ggtgaccagg tccttgttga
      481 ggtcgaaggt ggcgaccttg gcgccgctgt ccgcctggtc cgccgccttt accgcggcga
      541 gcgcgaactg ggcgccgttg gtgatgactt cgtcgatgtc gggttcctgg cgcagccgcg
      601 ccgccacggt ggtggtgacg gcgtccatgt ccgttccgtc cacgtagagc atctcggtct
      661 cgccggtgaa cgtcttcttc acgcccgcgc agcgcgcctc cagggcgatg ttgccccgct
      721 cgtggatcac gcacagggcg tgcttggcgc cgaggccgtc cagcttgtcg ccgacggccc
      781 ggcccgcgac gctctcgtcc tggccgaagt actccacgag ccccgccgaa cgccaggcgt
      841 cgataccgga gttgagtccc accacgggta tcccggccgc cctggcgcgg gccaccgggc
      901 tcttcatggc ctgcggcttg gcgagggtga ccgctatgcc gtccacccgg tcggcgatcg
      961 cgtcgcggac cagttctgcc tgtccgccgg cgtcggagtc actggcgtag gtcaggtcga
     1021 cgccgtcctt ggcggccgcg gcttcggcgc ccttgcgcac gagttcccag aagtcgtcgc
     1081 ccttggcgcc gtgggtgacc agggcgacct tgagccggtc gcccggcccg tctgccgcct
     1141 ttccctccga gccggacgcg gtggcgccgg agcagccggt cagcaggagg agacagcaga
     1201 ccgccgtgag ggcggtgcgg cggacggacc cgtgggggcc gtccgcggat cgagcgggga
     1261 ggggagtgtt catggggggc tgcacctcgc tgtgcggcag tgcggggagg acgggcgaac
     1321 atcgccgggg cgaggggtgt gcaccggctg gagggattcg ttggctcgga gccaaccgtg
     1381 tgtgaccgct gggagtcaag tgagccacca cttggtgcga ggcgccgctg ccgcatcgtg
     1441 atgctggagg gggccccggc ggcccggagg agcataaccg cagttgaatt gactgatcgt
     1501 caatccagcg gacccctccc gcgggtcgcg ccggacgccc accggcggtg gcacggtgcg
     1561 ctgcatctcg ggatcggcgc ccctcgcggc ggcggtacgg gtccacgcga cggcacgcga
     1621 cgccccggac agcgcccggc gagacatccc gcgcccccgg gccgcgggcg atggtgcgtc
     1681 cctcgcttcc gggcggcgct tcgtggggcg tccggcgggg gcccgggcca tggggggggg
     1741 agcgcgggta tgtgcgggtg cgcggtgcgc ggaaaccggc ggggccggga ccggcccgct
     1801 gtgcgcaggt cgtcccggcc ccgccggtga ggtgacgtac ggccgtgtcc acggccgcgg
     1861 gtccggtccg cgggcgtccg cgtcaggcgg gttcgcccgc tcccgagaag ccgtccttgc
     1921 ggaccgactc ggcgtgcgtc tcggtccggg cttccttgcg ctcctgccgg cggctcttgc
     1981 gcggctcctg gtcgggcagc cagccgaagg agatgctgct gcccacggcc cccagcagga
     2041 ggccgacgac gaagccgccg atgttcgacg tgagccaggt gcccagggag agcaggatgg
     2101 cgatgatcga gtagaacagc cgctgggtcg ggttgaagag gatcagcaga ccgcagacca
     2161 ccatcaggga aggcaggagg tatcccgcca gtccctgcat gcccacatga aggatcaccg
     2221 ggagcggtgc cttcatggtc accaggatct ccgcgccacc caggacgagc agcacgccgc
     2281 ccgcgaaggg ccggtggccc cgccacaccc ggaaacggtc ccgccactgg gtgaaggtca
     2341 ttacttgcag ccctcgctcg agaagctcat cttcaggccg ggcagcttga agacggccgc
     2401 ggtggcggcg tagttgtgct ggtacaggtt cttgatgacg accgtgtccg cctgctggcc
     2461 gtagacaccc gcggggccct ggatcgggac cttgtcgaag gtgctggagt cgcggccgat
     2521 ctcgatgttg ttgaactcgg cgtcgcccga gatctcgtcg gagtcgatcg ccaggttctt
     2581 cacgctcacc ggggtggacc cggcgccggc ccgcaggatc agctggatgc cgccgaggtc
     2641 gacgctctgg cacatgttgg tgatcttgcc gttcttcacg accgaggtga cgaccaggac
     2701 ctggccgccg gtgtcgccct ggttggggct gttctcgatc atgttgtcca ggccgccgaa
     2761 ctgggcgaag ccctcgccgt ccagccggtc cgcggtgacc acgaacggca tcccggagat
     2821 cgcgaactgc acgcccaggg cgccctgggc ggtgaggacc gcgagtcccg cggcgacgaa
     2881 ggtggcgggc accgccatga cggcggcccg gcgcagccgg acccggccgc gtctctctgc
     2941 ggaaccgctt tcggggttct cgggggtgtt gtcggcggac gaagtgacgt ccggggacga
     3001 ggccatgtct gctcccatgc gctgagtcgt gcgggttggg cttccgtggc acgttgtcct
     3061 ggcgcggaca gcggctgccg cgtacgcctc ctcacaactc ccggatgccg caagggcttt
     3121 ctggttacgc agcagtagcc gtccaggaag ttaccgatgg ttacaccacc cggtcaaggg
     3181 agatgtggaa aaagggtgtt cattatgtgc cgcctgcggg ccgtacgtcc cgacgggctt
     3241 tcgcatatat ctgtcggacc atcaacttgc tctcattgta ttgacgttga ctgtccatca
     3301 ggtctacaac tctccctggc tcagccggga tccgtggcgc cggatccgca gcgcggcgtc
     3361 cctgccgcgc tcccggacgc ttctcgacca gtccgtgcca ctcggcccgg gctcgatccc
     3421 taccggcacc ggtacggccg cttcccccca gcgggccggc cggtcgccct cgccgcccgg
     3481 tccggccgga gtcacccacc agtgcctacg tccggtcacc ggccggccgc cgttgccggt
     3541 ccgtcacgta cggagaaggc gtcacgggcc ggcggcggcg gacgccgatc cgcgtccccc
     3601 tccctgttgc gaccagcggc gcggcggcac accccgcaca tcaacccccc gaaaagcccc
     3661 acttgagaaa gaggcacccg catgcgcact cgctccctcc tcgccctcgc cggtaccgtc
     3721 gccgcgctct cgctcacggc cgtcaccccg gcctccgcgg ccggcgcggt gctgacgacc
     3781 gccaacggcg acgtggccgt cggcgacgtc ctcaacgcct ccctcgccag cggcacgacc
     3841 gccaccctct actccagcgc gaccggcacc agcggcgtct cctgtgcctc gtccggcttc
     3901 agcgccacgg tgaccgacaa ccccaccgcg cccggcacgg cgaccgagtc gctcaccgcg
     3961 cacaccttcg gcagttgcac cgcgaacgtc atcggcgtgc tcggcgtcac cagcgtcacg
     4021 gtcaacaacc tcccctacac cacgagcgtg tcctcgggcg gcaccgtcac cgtgaccccg
     4081 gcgagcggtt ccaccatcca gaccacggtc gtgctgcgca ccctgctcgg cagcatcaac
     4141 tgcgtctacc aggcgcccag cctgaccggc acggccaaca acgccgacaa cagcatcaac
     4201 ttcgccagcc agcagttcac caagacgtcc ggctcgtcgc tctgcttcgc gaacggctac
     4261 ttcaccgcca agtactcccc ggtgaccgac gcgggcgcgg ccgtcaccgt caactgaccc
     4321 accgtcgcac catgtgagaa gaacaggcgc ggcccgtccg cgtgaccgtc acccggtcat
     4381 cgcgcggacg ggttcagcgc cgacgcagtc gcgcgaccag ggcggcgccg ccggtgagca
     4441 ccagcaccgc cgcggcgccg cccgccagca cgggcgcgga cggtccggag ccgcccccgg
     4501 acacggacgc caccggggtg ctgtccggtc cggccgccgc ctcggcgggc gcggcggcgg
     4561 acacggtcga cgcggacgga gcggctgagg gcgaggcggg cgtcgtgctc gccgaggcca
     4621 cactcgttga cgccgtgggc cgggccgcgg ccggtgtctt cgtcgtcgcg cctgacttcg
     4681 gctcgccctt cgaggcggcc gccgcgggga acaccacgtc cgagcacgag tagtaggtgt
     4741 cgggcgtact ggtgttctgc cagatcgtgt agagcatctg acgccccgtc cggtcggcgg
     4801 gcagcttcgc cgtgaagcgg taggcgccgt tcgtcagggg cgggtcctcg acctcggcga
     4861 acggactcgc cgggagatcg gaccaggtga gcggcttcgt cgggtcgtac cccggtttcg
     4921 tcagatacag cttgaacgtg ccggtgtgcg cgatcgtcga ggcgtacgtc atgcgcaggg
     4981 tcccgcccgg ggtgagccgg gtcgagggcc agtcggcgcg ggcgaggtcg agtcctttgt
     5041 aggcgggcag accgccgctg cacagccgtc cgtcgggaac ggtctgccgg tcgcggccgt
     5101 tcacgtcggc cacccgcagg ttgtcccatg cggcgaagga ggtgccgttc gccgcgatcg
     5161 ccgcccggca ggccgccgtc ctcgcgtcgg ccccgccctc gggggaacag gcgtacaccc
     5221 ggctgaccgg atccgtcggc gcgccgtgcg cctgggccgg tgcggcggcc cacaggccca
     5281 gcagcagcgg gctcagcgcg gcggtcgcca gtgctgcggt gcggtgtgcg gtggtgcggg
     5341 gcatcgggga cgtctcctcg gccggcgcgg gaacggtcag ccgtcagtac gggatcgcgg
     5401 cccggcgcgt tcagcgcgcc accccgggcc cgccgcggcg ccctccgctt cgtgaccgtc
     5461 aagggtgccg ttccggccgg atcgagggtt tcccccgtat ccggatgacc agttctttgc
     5521 ctatcgttcc cccacagccg ccccacaggt aaccccgacc gggtcggcgt gcgcgcccgg
     5581 ccggctcttc tgcgcccttc gaggcacccc ccgccgcttc cccatcgaag cgaaaagacc
     5641 gccgctccgc cctgtccgga gccggtgacg aaaggcatcc ccttgcgcac ctcccccgcc
     5701 ctgagacgga agctgatatc cgtcgccgcg tcctccgcgg ccctgctcac cgccgcgtcg
     5761 accgcctcgg ccgtggcggc ccaggaaccc gtccccgccg gttccgccca ccccaccgca
     5821 cagatctccg ccgcgaccga ggcggcaccc ggcgtcccgg ccgagcgcct catcgtcggc
     5881 tacaagtccg gcgccgcgga ggcgaagtcg aacccggccg ccgaggccga cgccgccgcc
     5941 aagggccggg cgagcggtga ggacgtcgac ttccggcgac ggctcggcac cggcgcggcc
     6001 ctcgtcggtc tcggcgacgg cctctcggcg gcggacgtcg ccgacgtcgt cgaccgctac
     6061 cgggccgacc cggaggtcgc ctacgtcgtc ccggaccggc tgaacaagcc gaaggccgac
     6121 ccgaacgaca ccgagtacgc caagcagtgg gacctctacg agaccaccgc gggcatgaac
     6181 gtccccggcg cctggcccac gtcgacgggt acgggtgtca cggtcgccgt catcgacacc
     6241 ggttacgtcg cccacagcga cctcgccgcg aacatcgtcg gcggctacga cttcatcgcc
     6301 gacacggccg tctccgtcga cggcgacggc cgcgacgcca acccggccga tccgggcgac
     6361 cactacgcgg ccaacgagtg cggttcgggc atcccggcct ccaactcctc ctggcacggc
     6421 acccacgtgg ccggcaccat cgccgccgtc accggcaacg gcaagggcgt cgcgggcatc
     6481 gcgtacggcg cgaagatctc cccggtccgc gtgctcggca agtgcggcgg ctacgactcc
     6541 gacatcatcg acgcgatcac ctgggcgtcc ggcggcacgg tgtccggtgt gcccgccaac
     6601 gccgatgtcg ccaaggtcat caacatgagc ctcggcgggg acggcgcctg cacctcggcg
     6661 acgcagaccg cgatcaccgc cgcggtgaac cggggcacga ccgtcgtggt ggccgccggc
     6721 aacgagaacg acaacgtcgc caaccactcg ccgggcaact gcaacaacgt catctcggtg
     6781 gcggcgacca accgcaccgg cgcccgggcg tcctactcca actacggctc cctcgtggac
     6841 atctcggcgc ccggcggcca gaccagcacc ggcaccgcga acggcatcct gtccaccctc
     6901 aactccggga ccaaggcgcc gtccgccgag tcgtacgcct actaccaggg caccagcatg
     6961 gccaccccgc acatcgcggg cctggtggcg ctggtgaagt cggcgaaccc ggcgctgacc
     7021 ccggcccaga tcgaggcggc cgtcaaggcc aacgcccgcg ccctgcccgg cgcctgctcc
     7081 ggcgggtgcg gagcgggtct ggcggacgcc gcgcggacgg tgcaggcggt gagcggctcc
     7141 ggcggctcca cggcgggcac cacctacgcc agcacgaccg ctctttcgat tcccgacaac
     7201 ggggcggccg tcgagtcgcc gatcaccgtc ggcggccgta cgggcaacgc cccgagcgcc
     7261 cttcaggtcg gggtcgacat cacccacacc taccgcggtg acctggtgat cgatctggtc
     7321 gcccccgacg gcaccgccta ccggctcaag gcggccagtt cctccgactc cgccgacaac
     7381 gtcaccacca cctacacggt ggacgcttcc ggcgagagcg cgaacggcac ctggaagctg
     7441 cgcgtacagg acaccgcggc gcaggacacc ggcaggctga acggctggaa actgaccttc
     7501 tgagtggttt cgccgtcgtc tcgtgcgacg aacggggcgg gccggccggt gtcgagggac
     7561 accggccggc ccgcccgttt tcgcgtcggt caccgggccg gtgcccggcc gacggcctcc
     7621 ggcgcgccac ggcacgtccg cggtccgcgg gcccacgggg gtccgtgccc gtcgccaccc
     7681 cgtatcaggc ccgacgacaa acggaaacag cgcaacccgt ctttttcatt tccgtctcga
     7741 ttatgcctcc ggtacgttct gtgtgggatg ctcccgtcag ggggccgaca acgtcccaca
     7801 agtcggcggc gcatgacggc tgtcggcgca tttcacccct tggcctcact gccgtaccgt
     7861 gagctattgt gtacgcgggg tgagaaaaaa cggcatgtcc cgttcgttac cggcccggga
     7921 gagtaccagt cgatggcgag gcagttacgc gccgaacaga cccgcacgac gatcatcacg
     7981 gccgccgccg acctgttcga ccggcacggc tacgagtcga cgagcctcag tgacatcgtc
     8041 gcgcacgccc atgtgaccaa gggcgccctc tacttccact tcgccgcgaa ggaggatctc
     8101 gcccatgcca tcatggagct ccagtcctcg gcctcccgcc ggatcgccgg tgagatcgac
     8161 gaccgcggct acgcctccct cgaagcactg atccgcctga cgttcgccct gacccggctg
     8221 tccgtcgagg gcccgatcgc ccgggccgga ctgcggctcg ccaccggcgg agtgccggtc
     8281 cggccgcctc tgccgcaccc cttcgtcgag ctgaccgacc tgatctcccg ccggctcggc
     8341 ggcgcgctca aggaatccga catccatcag gacgtcgaca tcgatgccgt ggcccattcc
     8401 ctggtctgtt tcttcgtcgg cacccgcgtc gtcggccgca cccgggaacc cgccggccgg
     8461 ctgccccgcc ggatggccga gatgtggcac gtcctcatcc gcggcctggt gcccgtaccc
     8521 cgccggcccc gctatctcag cctcgccgcc cggctggaac gcgagatcat gcccgcggtg
     8581 tgagggcgcg gcgcccggtc gtgccgcggg tgaggctcgg ccccgccgac gggcccccgg
     8641 gatacggtga tccgcatgtc cgacaccccc gcgccgcccg tgatcctcgg cgacgagccc
     8701 ggctcgttcc cccacagcgt gctcgccgaa cggcacccgg cgatcatccg gcaggtacgc
     8761 gaggcgttcc cctacggtcc cgacgtccac cggagactgg acgccctgcg ggagagctgc
     8821 gccgagggcg tcgtcgaagc cctccccgac acggcgcccg accgggaccg gtggcgcgac
     8881 tggggtctcg acgcctacgt cggccgctcg tggttcgacg tgccctggct gtggtcggag
     8941 agctacttct accgtcaact gctcgaagcc gtgggctact tcggcaccgg gccctggcgg
     9001 ggcatcgacc cgttccgccc cttcaagctc gccgagctcg acgcaccgga gaccgacgcg
     9061 gaactggccg cgctggacgg cctcggggcc cgcccggccg gggaacggga ccgcgccctg
     9121 ctgcacggat ccctctgggg caaccgcgcc gacctcggct tccggctgtc cgacgcccag
     9181 gcgcaggaac gagccgccgt accggcactg gtcgccgacg acagcgacac gttctggtcg
     9241 ctgctgcccg cgggcgacac cgcccgcacc cggacgctgt gtctggtggc cgacaactcc
     9301 ggacgcgagc tgatccccga cctcctgctg gccgcccatc tcctcgccca ggggcggtgc
     9361 ggccgcgtcg tcctccatgt gaagccgtac ccctactacg tctcggacgc cacgacggcc
     9421 gacgtcgtcg acgcgctgcg caagctgacc ggagcgccgg gagccgccgc ggaccacggg
     9481 cggcggctgt ggacggccat ggccgagggc accctgacga tccgcgccca cccgttctcc
     9541 gccgcgccgc tgccctgtac ggcgatgccc gccgacctgc gggccgagtt cgcgcaggcc
     9601 gccctgaccg tcgtgaaggg cgacctcaac taccgccgtc tggtgggcga cagcagatgg
     9661 ccgcccacca cgcccttcgc cgacgtcacc gcgtacttcc ccggcccggt cgcggccctg
     9721 cgcaccctga agtccgacgt gatcaccggc ctggacgccg gcacggaagc cgcgctggtg
     9781 gccgccgagg gcctgcgctg gcggacggga ggcacacacg ccctgatcca ggtacgggag
     9841 tgaagccgga gcgggaccga tcgccgtgcg ggagcgaccg ggtccacgcg cgcgcacgcc
     9901 gggtccgccg ggtttcaggg catcgcgcct gattcacgcg atggtgtgat catgtgtcgc
     9961 ccggcggatg gctccggcga cccccgggta gggcccggcc atgacgcaac cgttcgaact
    10021 cccgcacttc tacatgccgc atcccgcgcg cctgaacccg cacctcgaac aggcgcggac
    10081 ccactcgacg cggtgggcac gcgacatggg catgctggag gggtccggga tctgggaaca
    10141 ggccgacctg gaggcgcacg actacggcct gctctgcgcc tacacccacc ccgactgcga
    10201 cggccccgcg ctgtcgctga tcaccgactg gtacgtgtgg gtgttcttct tcgacgacca
    10261 cttcctcgac atgttcaagc gcaccccgga ccgcgcggcg ggcaaggccc acctcgaccg
    10321 gctgccgctg ttcatgccgc tcgacctgtc gactcccgtg cccgagccgc gcaatccggt
    10381 cgaggccggc ctgaaggacc tgtgggagcg caccgtcccg cacatgtcgc aggactggcg
    10441 gcgccgtttc gccgtcgcga cggagcacct gctcaacgag tcgttgtggg aactgtccaa
    10501 catcgacgaa gggcggatcg ccaaccccgt cgagtacatc gagatgcggc gcaaggtggg
    10561 cggcgcgccc tggtccgccg ggctcgtgga gtacgcgacc gccgaggtcc cggccgccgt
    10621 cgcgggctcg cggccgctgc gggtgctgat ggagaccttc tccgacgccg tgcacctgcg
    10681 caacgacctg ttctcctacc agcgcgaggt cgaggacgag ggcgagaaca gcaacggcgt
    10741 gctcgtcctg gagacgttct tcggctgcac cacccaggag gccgccgaca ccgtcaacga
    10801 catcctcacc tcccgcctgc accagttcga gcacaccgcc ttcaccgaag tccccgcggt
    10861 ggccttggag aagggcctca cccccggcga ggtcctcgcg gtcgccgcct acgccaaggg
    10921 cctccaggac tggcagtccg gcggccacga atggcacctg cgctccagcc gctacatgaa
    10981 ccagggcgcc gtgtccggga caccctggag caagccgacc gggcccggca cctccgccgc
    11041 cgacctcggc gcgctgctcg ccccggccgt cgtcgcgggg gcgcttcccg ggcagcgggg
    11101 gaggctgcgg gcgtacgcgc acgtgccgtt ccggaaggtc ggcccgtcgc tgctgcccga
    11161 cttccacatg ccctacgagg tcaggctgag cccgcacctg gaggcgtgcc gcccgcgtct
    11221 gacggcctgg tcgcaccgga tgggcatcct gcgcgagggc gtctgggacg aggacaagct
    11281 cgccgccttc gacctcccgc tgtgctcggc gggcctggac ccggacgcca cccccgaggc
    11341 gctcgacctc agcgcccagt ggctcgcctg gggcacctac ggggacgact actacccgct
    11401 cgtctacggc aaccgccgcg acctggccgc cgcccggctg accacggccc gcctctcggc
    11461 gtgcatgccc ctcgacggcg aggaggcgtc cgtcgtcccc gtcaacggca tggaacgcgg
    11521 cctggcagac ctgtgggccc gcaccaccgc cgacatgacc gccgacgagc ggcgcaccct
    11581 gcgtgccgcg atcgacgcga tgaccgagag ctgggtgtgg gagctgtcca accagctcca
    11641 gaaccgtgtc cccgaccccg tcgactacct ggagatgcgc cgcgccacct tcggctccga
    11701 gctcacgctg agcctgtgcc gcatgggccg cggcccggcc gtcccgccgg aggtcggcac
    11761 gagcggcccc gtcgccgcgc tggagaacgc cgcgatggac tacgcgtgcc tcaccaacga
    11821 cgtcttctcg taccagaagg agatcgagta cgagggcgag atgcacaacg cgatcctcgt
    11881 cgtgcagaac ttcttcggct gcgactaccc ggccgcgctc ggtgtcgtcc acgatctgat
    11941 gacccagcgc atgcagcagt tcgagcacat cgtcgcgcac gaacttccgg tgctctacga
    12001 cgacttcgac ctctgcgccg aggcgcgcgc ggcgatgggg cgctatgtcg aggaccttca
    12061 gaactggctg tcgggcatcc tgaactggca ccgcgaggtc gaccgttaca agccggccta
    12121 cctggcccgt cgcacccacg gcttcctgcc ggacctcgcc ccggcggcgc ccctcccgca
    12181 cctgtcggct gccggactcc ggtagcgcgg ggtcagtctc actcgttcgt ggctcgtggt
    12241 gtgcccggcc cccgggtaga tcaccagccg gaggcgaacc atggaacaga cagcgttgcg
    12301 acccaagccc ctgcccggct ccgagcccgg cgggggccga ccggacaccg gtgcacgggg
    12361 gcgtcccccg cgcacggcgc gacggcgcgg caagcggctg gcgaccctgc tgctcggcgt
    12421 gtccgcgggc accgtcctgg tgctgtccgg ggtcggactg gccaccgtgg ggacgaccgt
    12481 gctcggcctg agcgcaccgg ccgggttcca gcggcaggcg gtcccgggcg cctcgggcac
    12541 cgggcccgcc ccgggccgcc cggtcccggc cgcgccgtcc ggcgcgtccc gcccgccggg
    12601 gtggtccgag gcctccgccg cgacgccgcg cccgcccggc gcgcccctcg gcctggaggc
    12661 ggtggacgcc gaagggccgg gcgccaggat cgtcgcggtg cacgtacccg gccccggcta
    12721 ccgggcgggt ctggtccgag gcgacgtgct gctcacgttc ggcggccacc ggatccgctc
    12781 ggcgaccgac ctcgcacgag cggtcgacga ggcccgaccg ggacgagcga tcgaactgac
    12841 ggtacgtcac cgagacggcc gggaagccgc attgacggcg ctcccaggcg tcgtcacctg
    12901 accgcccccc aacggcgccg cccgccgcga cccaccgtgg gcgtgaccgc cccggcccgc
    12961 cggcgcccgt ccgtcggcgt cgtccgcagg cccactgccg cgtggtcgcc cgcgcggcct
    13021 gccgacgccc acccgtgacc ccccaggggc ccttcccctc gtaccggaac gttcggcgtg
    13081 ccccgtaccc ccgacctgac cggcgccccg cccctcggct gccgccgccg cgcggctgac
    13141 gcccgccccc cacggctgac gtccgggggc ggccggggtg gcccagtgac ggcctggggc
    13201 gccgcaccaa agccgacccc ggtgacggcc cggggcggcg cccgaacccc gggccggacc
    13261 cgtcccgggg gtgttcgccc gtgcgtaaca tcgtcaaccg gctcgcgcga ccccctccgt
    13321 gcgggcagga tgctgctcgt gggcgtctcc acgtccgtca cgtccgtcac acgtcagtcg
    13381 ccacgtccat tctgggaggc ccggatgacc ggcaccgccc ccgcgccctt caccgccgac
    13441 gactaccggg cccgtatgca gcgggccgcg cgggaggccg ccgacgccgg actcgccgga
    13501 ctgctcgtgg cgccgggacc cgacctcgta tggctcaccg gctacgcgcc caccgccgtc
    13561 accgagcggc tcacgatgct cgtcctcgcc cccggccggg accccgtcct ggtggtgccg
    13621 acgctggagg cccccgacgc cgcgaaggcg gccggcgcct ccgcgctcac cctgcgggac
    13681 tggaccgacg gcaaggaccc ctacgccgcc accgccgccc tcctcgacac ggacggccgg
    13741 ttcgggatca gcgacggcgc ctgggcgatg cacctcctcg ccctccagcg ggccctgccc
    13801 gccacctcgt acgcctccct cacggacgcc ctgccgatgc tgcgggccgt caaggacgcg
    13861 gcggagctgg agctgatggc ggcggccgga gcggccgccg acgccgcctt cgaggagatc
    13921 cgccgggtcc ccttcggcgg acgccgggag aaggaggtcg gcgccgacct cgccgacctg
    13981 ctgcgccgct tcgggcactc ccaggtcgac ttcaccatcg tcgcctccgg gcccaacggc
    14041 gcgaacccgc accacgaggt cggcgaccgg gtcatcaggg acggtgacat ggtcgtcctg
    14101 gacttcggcg gcctcaagga cggctacggc tcggacacct cccggaccgt gcacgtcggg
    14161 gaacccaccg aggaggagcg ccgggtccac gacctcgtgc gcgaggccca ggaggccggt
    14221 ttcagggcgg tccggcccgg cgtcgagtgc caggaggtcg accgggcggc ccgcgcggtg
    14281 atcaccgacg ccgggtacgg cgagtacttc atccaccgca ccggccacgg catcggcgtc
    14341 accacccacg agccgccgta catgatcgag ggcgaggagc ggcccctgga gcccggcatg
    14401 tgcttctccg tggagcccgg cgtgtacctg cccgaccggt tcggcgtgcg catcgaggac
    14461 atcgtcaccg tcaccgagga cggcggccgc cggctcaacg acaccacccg cgagctggtc
    14521 atcgtgggct gacccacctc tcaggagtcc cggcacccat ccgaacggcg acgacgcgac
    14581 catgacccag gcaccgacac ccaccgcgga caccgtccgc cggctggtcc gcgccctcct
    14641 cgaggagggc ggcacggcgg gcggcccggg gccggaggtc cggcccgtcg ccccgggcgg
    14701 cacgcccgcg acctggtggg tcggcgcccg ccacgtgctg cgcctcgcca ccgaccgcga
    14761 gacgaccctg cggcgggccc gcgaactgcg gctgcgcgac ctcgtccgcc cgcacgtccc
    14821 ggtcgccgtg cccaccagcg tcgcgcacgg tgagtggtcg cccggactgg tgtacaccct
    14881 cgacaccaag ctgcccggcg gcaccgccga ggaacacgac gtgtccgccg tcggcgaggc
    14941 cgacctcgcc ggactgctgc gcggactgcg cgaggtgccg ccccggcagg ccgagacgct
    15001 cggcgtgccc cgcgtcgccc cccgctccct ggaggcgctg cgccggatgg ccgtcgccgt
    15061 cgccgaacga ctcgcccgcg ccgacgagtt cgaccccacc cgcctccacc agctgacccc
    15121 gcccggcgcg gcccagctcg ccgcccagcc cggcagcgcc gtcctggtcc accacgcgct
    15181 gcgcggcgag catctcgtgg tgagcgccga cggccgggtg cgcggcgtcc tcgactggac
    15241 cggcgcggtc ctcggggacc cggccgagga catcgccggg ctcgccctcg ccgtcggatc
    15301 cggcgccgcc gtccgcgccg ccaccctcgc cggttacgga gcccgcccct gtctgcgcgg
    15361 tctgtggctg gcccgctgcg acaccgtcct gcggctcgcg gaaggtctcg acgcgcggac
    15421 ggccggaccc cgggacgccg aagcgctcgc cctgccccgg acccggctgg gacgggcctg
    15481 ggaggcgatc ctgctcgaac gggtcaccga gttccgcgag gagggcgagg acggaccgga
    15541 cgagaaggtg tgagcccccg tcaccggcac ccccgcgccg gcgccccctt cacctgagcc
    15601 cgcgcaccgg cacccccgca ccggcactcc ctcactgctg ctccagcacc acgcaggact
    15661 cgccggggac gtgcagcagt ccgtcccggc ccggtacgtc caccggctcc caggtggcga
    15721 gcacgcgggc cgggcgcggg ccgaggggga tcgcggccgt ctccttgccg aggttcacgg
    15781 ccacccggac gtccccgcgc cggaacgcca gccagcgcgc ctccgggtca tgggcgatct
    15841 tgatgtcggc caggtcggga tcggtgaggt ccgcggtcgt gtgccgcagc gcgatcagct
    15901 cgcggtacca ggccagcacg cgcgcgtggg gctcgcgctc cggctccgac cagtcgaggc
    15961 acgaccgctc gcgcgtcgcc gggtcctgcg ggtcgggcac gtcctcctcg gcccagccgt
    16021 gcgccgcgaa ctcccgtcgc ctgccccgcc gtacggcctc ggcgagttcg gggtcggtat
    16081 ggtcggtgaa gtactgccag ggcgtgcccg cggcccactc ctcgcccatg aacagcatcg
    16141 gcgtgaacgg ggcggtcagc gtcagcgcgg ccgcgcacgc cagcagcccg ggggagaggg
    16201 acgccgacag gcggtcgccc tgggcgcggt tgccgatctg gtcgtgggtc tgggagtacc
    16261 cgaggagccg gtgcgcgggc aggcgggccc ggtccagcgg gcggccgtgg ccccggcccc
    16321 ggaagccgga gtacgtgccg tcgtggaaga agccgccggt cagggtcttg gcgagggcgg
    16381 cgaacggggc gcgagcgaag tcggcgtagt agccctggga ctccccggtg agcgcggtgt
    16441 gcagggcgtg gtggaagtcg tcgttccact gggcgtgcag ccccaggccg ccgtcgcggc
    16501 gcggggtgat cagccgcggg tcgttcaggt ccgactcggc gatcaggaac agcggccggc
    16561 cggtgtcggc ggccagggcg tccaccgccg cggacagttc ctccaggaag tggcacgcgc
    16621 gcgtgtccgc cagcgcgtgc acggcgtcga gccgcagccc gtcgagccgg tagtcgcgca
    16681 gccaggccag cgcgctgccc acgaggtagg cgcgcacctc gtccgagccg ggcgcgtcca
    16741 ggttgatggc ggcgccccac ggcgtgtggt gcgtctccgt gaagtacggg ccgaacacgg
    16801 gcaggtagtt gcccgacggg cccaggtggt tgtgcaccac gtccaggacg acgcccagcc
    16861 ccagctcgtg ggcccggtcg acgaacctct tcagggcctc ggggccgccg tacggctcgt
    16921 gcaccgccca gggcgccacc ccgtcgtacc cccagccgtg ccggcccggg aacgcgcaca
    16981 gcggcatcaa ctcgacgtgc gtcacgccca gttcggcgag atgcccgagg cgttgcgcgg
    17041 ccgcgtccag cgtgccctcg ggggtgtacg tgcccacatg cagctcgtag aggaccgcgc
    17101 ccggcagcgg ccggccggac caccgcgtgc gccactcgta ccgcgcgtgg tcgacgaccg
    17161 cgctcagccc gtccggcccg tccggctgac ggcgcgagcg ggggtccggg cggaccggtc
    17221 cgtcgtccac cgcgaacccg taccgcgagc cgtcggcggc ttccgcctcg ccggtccacc
    17281 accccgcccg ctccggatcg cgctccagcg cgcgcgtggt ccggtcgcac cggagcgtca
    17341 cacgttcggc ctgcggtgcc cacacctcga actgcacgga cggttcccct tcgtctgccc
    17401 accgtgatgt tgcccgtccc ctccatcgtg ctgcacggga ggtcaatccg cttttggaac
    17461 actcccattg gccgcacgcg tgtgggccgg gcgtttccga gtcttctgga cacccggggc
    17521 gcgctgaccg acaatcacca ccgtgacgtc gtccttcgag ttcaacacgt accccgcgcg
    17581 gctgtccgac gtggagcgcg accgggcgct gaaggtgctg cgtgacggcg tcgccatggg
    17641 gcgcctgtcg cacgacacgt tcatccggcg catggagctg gcgctcgtcg cccgccgctc
    17701 ggacgagctc gccgtcctga ccgccgacct gccccgggag aaccggttct cccgggtcgt
    17761 cttcggcacc gtcgaggccg tctccggctt caccgtccgg gtgcgcaggg cctggcaggc
    17821 cgagcggctg cccaagctgc tgctgccgca tcccggcacc cgccacgcgc tgcgcatcgg
    17881 ccgcgatccc gccagcggtc tgcgactgac ccacgagagc gtctcgaggg tccacgccga
    17941 gctcgcccgc cagggcggga tgtggatcct gcgcgacctc ggctcgacca acggcaccac
    18001 cgtcaacggg cgccgggtga tcggcgcggc cgtggtgcgc gagggcgacc aggtcgcctt
    18061 cggccggatg gccttccgcc tctcgacgaa ctgacccgcc cgcccgtccg cacgtcgccc
    18121 ctccgccgcc cgcccggctc gtgcggcccg gccaagtccg cgtgcgcgcg gcggtgttga
    18181 cgtacccccg gcccatgact cactgtgcgt acaccagaca cgcccggtaa acgacggcgc
    18241 cgccccgtgg aggtgtgccc tgccgccact cctccgctac ccgaccgtgg acgaggtcgc
    18301 cgcccgcgcg gccgtgctcg ccgtccgtgg ttccggggac gccaggctgc gccgcgtcgg
    18361 ggtctcccgc gcgggctcac ccctgtggct gctgtccttg ggccgcgggg cgcggcaggt
    18421 cctcgtcgtc gccggaccgc acgccaacga gcccgtcgga ggtgccacgg tgctgcggct
    18481 cgccgaacgg gtcctcgccg acccgcggct caccgtcggc gccgacgcca cctggaacct
    18541 gctgctctgc ctcgacccgg acggtctgcg ccgcaacgag ggctggctga ccggcccgta
    18601 caccctcggc cgctacttcc ggcacttctt ccggccgggg ttcctggagc agcccgagtg
    18661 gctgcccgac ggcgcggccc gcgccgcgct gcccgagacg cgtgcgctgc tgcgcctcca
    18721 ggacgaactg cggcccttcc tccagtgctc gctgcacggg gtcgacgtcg gcggcgcctt
    18781 cgtggagctc acccgcgacc tgcccggact ctcccgccgg gtcgcccaca ccgccgcccg
    18841 cctcgggatc ccccgtgagc tcggcccgtt cgacaccctg cactggcccc gcctgggacc
    18901 cgccgtctac cggatcccgc cgccgcgccc gggcgacctg gccgccgcca tcaccgaggc
    18961 ggcggtcgag tcgacctggt accacccgca ccgctacggc acggtcaccg cggtcgtcga
    19021 ggcgcccatg tggggggtcg ccgccgcgga ggacgactcc cggcccgccg accgggacgc
    19081 cgtcctgcgg gccgtgagcg gtgccctgcg ccatgacgca cagttgctgg aacgtatcct
    19141 cacccgggtg cggccgcacc tcgccgccac cgcggaagcg gcccggctgc tcgctccggt
    19201 cggcgaccat ctgctcgtct gccccgccct cgcggacgcc tgggaccccg ccaccgccga
    19261 cccccgccgc ccgctcccgc cgctcagcac cgcccatctg accgccctgc gcatcgccgg
    19321 gcgccggatc gcggtccgga cggcgggact gctccaccag ctcgtcgccg gctccggacg
    19381 cgacccggcc ggcgcgctgc cggagctgga cgggctcatc gacgcgtggt gcgccgggta
    19441 ccaggacgag tgcggggccc gctggatccc cgtcgcgcgc caggcggagt accaggcgcg
    19501 gatcgtgctc gccgcgttcg agctggcggg ccgggcaccg gcggaacccg cccgtgcccg
    19561 ttcgggtgag tcggactggg gttcacaccc ggccgtgccg atgcatcggg aatgacctac
    19621 ttcctcacct gtctccggtc ggcgaaagcc gtacggcgcg cgctcccggc cgcggccgcc
    19681 ctcctcctcg ccgccggcgc cgctccggca caggcggtct cccgcgacgg cctgtccggc
    19741 aactggctcc agctcaccgt cacccgcggt gacgcccgct ccagcgacac ccgcggcacc
    19801 ctgctcctgt gcgacccgcc ccagggtcac tcccgtgccg cggaggcctg cgacgtcctg
    19861 acgcgggcgg acggcgacgt gggcgccctg cacggcgaca gcggccgcgt ctgcgccctc
    19921 gtctacgcgc cggtgaccgt ccgcgcgcag ggcgagtgga acggccgccc ggtcgactac
    19981 cggcacacct tcagcaacga ctgcgagcgg gaggcgctca cgggggccgt cttcgccctg
    20041 gacgaccagg aggtccccga ggtctgaccc gtacggggcg gccccgcgca cgcccgcgtg
    20101 ccccgggccg ccccgccccg gccgcccgca gctctgcgat ccggaccgcg ccacacgcgc
    20161 gtgcccgggt cttcgcgcgt cacgcggccc gttcgcgcgc gtgcagggcc gccgcgacga
    20221 ccgtgcggga ctggtgctcg acctggtgct ccaggggcac ccaacgggcc cggaagcggt
    20281 aggcgaaggc gtcgctccag gtctcgacga ggtgttccag acgcggggcg gcgtggtcgt
    20341 cgcactcctg gaggacccgc cacagcatcg cggccgcgcg caggggcagc cggcgcgcga
    20401 aggcgtccac gctgccgacg tacgccatcg tcgtgtcggc gggcggggtg tccgtccagt
    20461 ccgcggccag ccccggcacc agctccagcg cccacttcgc cgcccgcagc aggggcccgt
    20521 cgacgccctc cagacgcggc agggcctcga cgagcacccg ctccacctcg gtcgtgtccc
    20581 gcagcagccg ccgcgcgagc cgccgtatcg ccgccgccgg agcggggtgc tgggccgggt
    20641 cgtccaccat gtcgctcgcc cacatcggca cctccaccac cgccgtcaga ccgccgtagc
    20701 ggtgcgcgtg gtaccaggtg ctgtgccgtg cgtcgtcggg catgctcggg tacgccgcct
    20761 ccgcgccggc cgccggcatc acgtgcacgc cgggacccga ggcgggccag cccgccgcgt
    20821 cggaggcgcc ggtctccacc gggatgtgca gctgcgccgc ggacttggcg aacggctcgg
    20881 ccagacccgg gatgtccttg gtcagctgca cccagctgcc gcccaggtcg gtgccgtgca
    20941 gggtgacctg gaggtagggc cgcagttcgt cgatgacccg ggtcagcgcc cgtgtctcgg
    21001 gcggcagccg gtccggcggc agcacggcgg gggaccactc gggctgctcg ggaccggcgg
    21061 gccggaagaa gccgaggtgg tactccagca gactgcgcgg agcgggggtc acgtgcaggc
    21121 tcgccccgtc ggggtccgcg cacagcagga agtgccagga cgtcccgtcc ctcagctcac
    21181 gctcctggac cacccgttcg gccagcgcca gcagcgtgga gccaccggtc ggctcattgg
    21241 cgtgggcgcc cgcgacgacg agcacggcac gccgggcgcg tcccacggag agcaggttca
    21301 gcggccggcc cgcacgggag acccccacct ggcgcaggac gcacagaccg ggtcggtacg
    21361 cggccagcgc ccgtgcggaa gagatcagtt cggtcaccgt ggggtagcgc agctccggca
    21421 ggagactcac ccccgtatcg gtccgcccgg ccttcgcacc cgcagtaccc catggtctcc
    21481 ggcaactgtc aaggacgcct gcggggcgcc cgcggggggc gctcggacgc gtacgccggc
    21541 cctgggtacg gacgttccgc gcgcgctcgc tcccgcccgg cgaggcggaa atcacccgta
    21601 agagttaacg gtgcgcgcac gccgtccccg cgccggccgc cgcccgccgg gcgaccaccg
    21661 tcacgccgtc accccacccg ctccagcagc gccaccggca gccgctcgaa cagctccgcc
    21721 acgtccgcct gccccgcgaa cgtccgcccg ggcgccagcg cgtcggtcca ggtccccggc
    21781 ggcagcgcga gccgggtgcc gcgccagccg cccgcctccg ccagccgcag cggcagccgc
    21841 gtcacggccg tcaccacccg gcccgagcgg acgaacgccg tgcagtggtc cgcggccgac
    21901 ccctcggcgg ccagcggctc gtacgtcgcc gacgccccga agacctccgg aagccgccgg
    21961 cgcagccgca gcgccgccga ggtcaccgcg tccttctcgc cgggagactc cggagggaaa
    22021 cccaccggac gccggttgtc cgggtcgacc agcgcccggt actcgccctc cgtgccctgg
    22081 tagacgtccg gcacccccgg catcgtcagg tgcaccagcg ccgtgccgag gacgttcgcg
    22141 cggatgtacg gctccagctc gccgcgcagc gcggccaccc gctcgcccgg caccccgcac
    22201 ggacc
//
