LOCUS       NZ_BMSI01000005        43078 bp    DNA     linear   CON 02-AUG-2024
DEFINITION  Streptomyces asoensis strain JCM 4185 sequence05, whole genome
            shotgun sequence.
ACCESSION   NZ_BMSI01000005
VERSION     NZ_BMSI01000005.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces asoensis
  ORGANISM  Streptomyces asoensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 447467)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014649075.1-RS_2024_08_02
            Annotation Date                   :: 08/02/2024 04:45:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,813
            CDSs (total)                      :: 7,736
            Genes (coding)                    :: 7,563
            CDSs (with protein)               :: 7,563
            Genes (RNA)                       :: 77
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 53 of 173
            Pseudo Genes (incomplete)         :: 140 of 173
            Pseudo Genes (internal stop)      :: 10 of 173
            Pseudo Genes (multiple problems)  :: 28 of 173
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:21:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 324768
            Orig. end                         :: 367846
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMSI01000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..43078
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NRPS"
                     /region_number="3"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..43078
                     /SMILES="N1C(CCC1)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..43078
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[20000:23078](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..23078
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            201..452
                     /locus_tag="IE189_RS15685"
                     /old_locus_tag="GCM10010496_32050"
     CDS             201..452
                     /NRPS_PKS="Domain: PP-binding (13-67). E-value: 4.3e-11.
                     Score: 35.0. Matches aSDomain:
                     nrpspksdomains_IE189_RS15685_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012759.4"
                     /locus_tag="IE189_RS15685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32050"
                     /product="phosphopantetheine-binding protein"
                     /protein_id="WP_189921951.1"
                     /sec_met_domain="PP-binding (E-value: 4e-09, bitscore:
                     31.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding_2 (E-value: 0.0011, bitscore:
                     13.9, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRDEVLQEIHQIAKEFAASSGRTVNENSSNFLEAYGFTSLDALE
                     FLLLLEERFGVTFEDEDLTEDTLTSEDRLADYVIERLG"
     aSDomain        240..401
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS15685_PP-binding.1"
                     /evalue="4.30E-11"
                     /label="IE189_RS15685_PP-binding.1"
                     /locus_tag="IE189_RS15685"
                     /protein_end="67"
                     /protein_start="13"
                     /score="35.0"
                     /tool="antismash"
                     /translation="AKEFAASSGRTVNENSSNFLEAYGFTSLDALEFLLLLEERFGVTF
                     EDEDLTEDT"
     gene            473..1219
                     /locus_tag="IE189_RS15690"
                     /old_locus_tag="GCM10010496_32060"
     CDS             473..1219
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016908.4"
                     /locus_tag="IE189_RS15690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32060"
                     /product="FkbM family methyltransferase"
                     /protein_id="WP_189921953.1"
                     /transl_table=11
                     /translation="MTPPKLTEVAEGFSVHAVSALDARFLYREMFEGGTYAGISLPDEP
                     FVIDVGANIGLFTLFVKQRRPKARIEAFEPLPELVAALHANVAEFALHDVAVHETALGS
                     KEAAGVSFRYYPLLPSSSTLYPQDQGQLRELLSQSFPPRVVERMFQGRETTVTVERLSR
                     HIGTDRPVDLLKIDAVGSELEILRGIDAELRPLLRNVVIDVQDVHGRVDELCSCLREMG
                     MEPSVLKPPMAGGEDTLNHLIHAVRP"
     gene            1260..2987
                     /locus_tag="IE189_RS15695"
                     /old_locus_tag="GCM10010496_32070"
     CDS             1260..2987
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Carbam_trans_N"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129800.1"
                     /locus_tag="IE189_RS15695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32070"
                     /product="carbamoyltransferase C-terminal domain-containing
                     protein"
                     /protein_id="WP_189921955.1"
                     /sec_met_domain="Carbam_trans_N (E-value: 8.5e-36,
                     bitscore: 118.7, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTLGLGGSNHDFAACLVSDGVIAAGIEEERVRRVKYSVGVNSLF
                     NESWRYCLDMAQARLADVDVIVADDTLLAPAYFPFRKRIHLIRHHMAHAASTFFPSPFE
                     RAAILVVDGAGSLIDDRGVETLTTAVGEGTTITEVSKVLGTNWSTDGLSALRVYQAGDS
                     DHSLGYMYKAVSKAIGFVLYENEYEGRHWYLSEDGKTMGLAPYGTSRYCKEFREYLTLL
                     PDGRYELHLKNGGLLDFIEHALDGYTGDERFARAADLAYAAQDTLEETLLHVARRLHAD
                     TGLTDLCLAGGVALNCVANGRLLRETPFENVFVQPAAGDGGCAVGNAYYGYHVIAGRPR
                     EKPARTAQRHAYLGRTYDDGQVRAALDASGLPYRKVDEPSRLGAELLAQGKLLGWFTGG
                     AEFGPRALGHRSILADPRRAEMKDIINSRVKHREPFRPFAPAVLREHAADYFDLDIESP
                     YMLIVAPVRPEKQGEVPAIVHVDGTARVQTVTAEDNGAYHGLIEHFHRLTGVPVVLNTS
                     FNDNGQPIVETPQQALEFYGGSRLDWMIIENYVVAHSADDLDALASTLSSATGSPATD"
     gene            3010..4221
                     /locus_tag="IE189_RS15700"
                     /old_locus_tag="GCM10010496_32080"
     CDS             3010..4221
                     /NRPS_PKS="Domain: Aminotran_1_2 (35-173). E-value:
                     1.3e-10. Score: 32.9. Matches aSDomain:
                     nrpspksdomains_IE189_RS15700_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129801.1"
                     /locus_tag="IE189_RS15700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32080"
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="WP_189921957.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 6.6e-101,
                     bitscore: 332.8, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 9e-10, bitscore:
                     32.9, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALALDGGNPVRRHDFPAWPYHDDTERAALVRAVDQGQWWRVGGS
                     EVTSFEAEFGEYHGGTTLAVTNGTHALELGLELLGLKPGDEVIVPAFTFISTSIAVQRA
                     GGVPVPADVDPVTYCLDPQTLEAVRTPRTRVVIPVHMAGHVADMDAIGAWAARHDIVVF
                     QDAAHAHGAVWSGRRIGDFGTLAAFSFQNGKLMTAGEGGALLLPSQEWFDEAFSRHSCG
                     RPLGDTDYEHRSPSSNYRMTEFAGAVLRAQLARLAEQNARRESRWKTLSAALREIPGVV
                     PQGRDPRCDLNPHYMAMAALDPAAHPGTDRDLVVKALVAEGIPAFVNYPPVYRTRAHEA
                     LLGNGLPDTAELAERNPVSEHLGANGFWLHHRVLLGTDADCADVAEAVAKVLTELAGKK
                     RSAR"
     aSDomain        3115..3528
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS15700_Aminotran_1_2.1"
                     /evalue="1.30E-10"
                     /label="IE189_RS15700_Aminotran_1_2.1"
                     /locus_tag="IE189_RS15700"
                     /protein_end="173"
                     /protein_start="35"
                     /score="32.9"
                     /tool="antismash"
                     /translation="QGQWWRVGGSEVTSFEAEFGEYHGGTTLAVTNGTHALELGLELLG
                     LKPGDEVIVPAFTFISTSIAVQRAGGVPVPADVDPVTYCLDPQTLEAVRTPRTRVVIPV
                     HMAGHVADMDAIGAWAARHDIVVFQDAAHAHGAV"
     gene            4218..5288
                     /locus_tag="IE189_RS15705"
                     /old_locus_tag="GCM10010496_32090"
     CDS             4218..5288
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014893.4"
                     /locus_tag="IE189_RS15705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32090"
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="WP_189921959.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 4.7e-19, bitscore:
                     64.0, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 1.8e-17,
                     bitscore: 58.2, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVAVIGLGWVAREVWLPRLVKHPDFDVVAVVEPRPEAVERAAAL
                     VGGAQVYGGFQELGPHEADLVFVLTPNHTHGALASHFLRQGLAVFLEKPTGTDFAHLRL
                     LEDAARDGGGRLLLSTAARHRADVGELARLVSDGALGTPRHAELSWVRSRGIPGSDWFA
                     RRETAGGGVLVDLGWHVIDVLHHLWGASGVRHATALASSDFLTRAGWGADWHAGTAGLA
                     DADVEDQLTALVVTERYGMQLRFAWASHEPVDRTRLVLHGTEGTAELTTTFGFSPRRVD
                     EPTLTLRQEGAERRVPLPPAGVGDEYDQQLDALAAELARPDATDRALREAREALAVVEA
                     CYRATSARWTAPETNS"
     gene            5285..6505
                     /locus_tag="IE189_RS15710"
                     /old_locus_tag="GCM10010496_32100"
     CDS             5285..6505
                     /NRPS_PKS="Domain: Aminotran_5 (47-175). E-value: 2.6e-10.
                     Score: 31.7. Matches aSDomain:
                     nrpspksdomains_IE189_RS15710_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129803.1"
                     /locus_tag="IE189_RS15710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32100"
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="WP_189921961.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2.2e-93,
                     bitscore: 308.1, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 9.1e-08, bitscore:
                     26.1, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTASLSEPTALRYEPLRGLALWGEEEKAAALDVLESRSLFRYYGP
                     ALQRRVERFEERFAALHQTPHAVGVSSGTAALTCALIGLGIPEGGEVIVPSATFIGCVN
                     AIVAARGVPVFADIDESLTLDPTAWEKLVTERTFAVMPVHLNNVAADMDPILAVAREHG
                     IRVLEDAAQACGVSYRGRPVGSIGDAGAFSFQLEKNITAGEGGAVVTTDPEVHDRVVRY
                     QDQGGQFTTSRSGERGGASGEAFLGANLRMTEIAGALLSVQLERLTPMLRRLRDVARTV
                     RADLADLELEWRRLPDEEGSGGDLTVLLADRMAARRFVTVLTAAGIPAATLYSGRLVQQ
                     NPAVRAGRTPWGVAWDATARLRASEAVLGRSVTVGLGATMTDDDVAHLVASMRTASEAV
                     RKGANRE"
     aSDomain        5426..5809
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS15710_Aminotran_5.1"
                     /evalue="2.60E-10"
                     /label="IE189_RS15710_Aminotran_5.1"
                     /locus_tag="IE189_RS15710"
                     /protein_end="175"
                     /protein_start="47"
                     /score="31.7"
                     /tool="antismash"
                     /translation="QRRVERFEERFAALHQTPHAVGVSSGTAALTCALIGLGIPEGGEV
                     IVPSATFIGCVNAIVAARGVPVFADIDESLTLDPTAWEKLVTERTFAVMPVHLNNVAAD
                     MDPILAVAREHGIRVLEDAAQACG"
     gene            6498..7157
                     /locus_tag="IE189_RS15715"
                     /old_locus_tag="GCM10010496_32110"
     CDS             6498..7157
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129804.1"
                     /locus_tag="IE189_RS15715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32110"
                     /product="HAD-IA family hydrolase"
                     /protein_id="WP_189921963.1"
                     /sec_met_domain="HAD_2 (E-value: 1.8e-28, bitscore: 94.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDLWPRAVVLDLDGVLIDSIHVMRRAFQRAYDLTVGEGEAPFEE
                     YLTHLGRHMPDTLAIMGLPVGMYEPFVVESRKLVHEIEPCPGAAELLAGLREAGVPTAV
                     ATGKTHGRAVEALSATGLLDLVDAVCGSDEVAHGKPAPDIVLLALEKIGAAADGAVMVG
                     DSALDLRAGRAAGTRTAAGLWGQGDREELLAHRPELVAGSCAELAALLLRREGTPA"
     gene            7154..7627
                     /locus_tag="IE189_RS15720"
                     /old_locus_tag="GCM10010496_32120"
     CDS             7154..7627
                     /EC_number="4.2.1.10"
                     /GO_function="GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129805.1"
                     /locus_tag="IE189_RS15720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32120"
                     /product="type II 3-dehydroquinate dehydratase"
                     /protein_id="WP_189921965.1"
                     /transl_table=11
                     /translation="MTIASTSRDLLLLNGPNLGTLGTREPGIYGTTTLAQVEETVAELL
                     ARAGYGLRSEQHDGEGELIRALHKHRDTVAAVVNPGALMIAGWSLRDALADYPAPWAEV
                     HISNVWARESFRHNSVVSPLAVGVIAGFGTHGYELAAQALVRRLESAAQGEAK"
     gene            7624..9771
                     /locus_tag="IE189_RS15725"
                     /old_locus_tag="GCM10010496_32130"
     CDS             7624..9771
                     /NRPS_PKS="Domain: AMP-binding (11-339). E-value: 6.5e-47.
                     Score: 151.9. Matches aSDomain:
                     nrpspksdomains_IE189_RS15725_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012711.4"
                     /locus_tag="IE189_RS15725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32130"
                     /product="AMP-binding protein"
                     /protein_id="WP_189921967.1"
                     /sec_met_domain="AMP-binding (E-value: 1.4e-40, bitscore:
                     133.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAANLWEAFARADLDPDAPALGDLSRRAAVSRVTELAERLRAQG
                     VRPAETVGLQGPNQPEWVLGLLALTAVGACPLLLPADSPPAETRRLLRTAGARRTLVTD
                     PGEAHGAVLRPHDGGTDDGSTGAGTGAVDADPGPSAPDPGTVVLVSSGSTGTPKLVARS
                     PRSVLDEGVRYHHAGLARREDRVLLPLPLSHAYALGWLAGALVAGAHVDPVPPRAVGSV
                     HSRLREGATVLVTVPGLARVLARRRALTDDAPFPALRRVMAGAGYVDVGLDALWSRALG
                     VGVSRNYGSSETGAVLWGEPGLPSGAVGRPMPGVRIDLLDPDGTPVPGGGAAQGELAVV
                     LEDGSVHRLHDLADRDEDGVHRILGRARLGVVRRGARWVSTLEVESVLRAAPGVADVSV
                     TATGAQDSDDQGLTVEYVPADTELASPARVQAYARAELAGFKVPDSFLPRYRLRRSAVG
                     KTQAAPAYRLARGARAATMAEQVLAAALTELGLPPLLAQGGTAADLAATTGLRAEVLSP
                     VLDTACALGLLVTDTFSAGAPGDWTLPPDVLPGGRALAARVRGETAPERPDPPAAPFGP
                     SAVTKALRASVEALLAETAVDGSLLEIGDGGAPPATDAEHGACVVLGGVHGPAAGLGSL
                     AALLRPKGLLVVADAFVDDPLALTDDMSRTLAVRWLVDGHLHWWTTQELRAGLEAVGLR
                     VEESRRAEQAPYAIVVARKPS"
     aSDomain        7657..8640
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS15725_AMP-binding.1"
                     /evalue="6.50E-47"
                     /label="IE189_RS15725_AMP-binding.1"
                     /locus_tag="IE189_RS15725"
                     /protein_end="339"
                     /protein_start="11"
                     /score="151.9"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="RADLDPDAPALGDLSRRAAVSRVTELAERLRAQGVRPAETVGLQG
                     PNQPEWVLGLLALTAVGACPLLLPADSPPAETRRLLRTAGARRTLVTDPGEAHGAVLRP
                     HDGGTDDGSTGAGTGAVDADPGPSAPDPGTVVLVSSGSTGTPKLVARSPRSVLDEGVRY
                     HHAGLARREDRVLLPLPLSHAYALGWLAGALVAGAHVDPVPPRAVGSVHSRLREGATVL
                     VTVPGLARVLARRRALTDDAPFPALRRVMAGAGYVDVGLDALWSRALGVGVSRNYGSSE
                     TGAVLWGEPGLPSGAVGRPMPGVRIDLLDPDGTPVPGGGAAQGELAV"
     CDS_motif       8062..8106
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS15725_0001"
                     /evalue="8.60E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="IE189_RS15725"
                     /protein_end="161"
                     /protein_start="146"
                     /score="12.4"
                     /tool="antismash"
                     /translation="VLVSSGSTGTPKLVA"
     gene            9768..10733
                     /locus_tag="IE189_RS15730"
                     /old_locus_tag="GCM10010496_32140"
     CDS             9768..10733
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF012692.4"
                     /locus_tag="IE189_RS15730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32140"
                     /product="ROK family protein"
                     /protein_id="WP_189921969.1"
                     /transl_table=11
                     /translation="MTDDRPRPHADTAGGVLAVDIGGTKLALRAVAAGTTVHERTVPWP
                     AGDDAEADSELLEACVAEAIAALPGAPVRIGVAAAPNVGADATVLSWPNRPTWVGRSLS
                     APFTGSGAEVLFGDDATLAALAEAVSTAGRDLAYLGIGTGVGGGLVSGGRLLTGAWGTA
                     GELGHLVTDPRGPRCRCGTRGCLQAVVSAEALAAHATAARGLPTSSAELVAGVERAEPW
                     AERTLDHAADSIAGALRVLAELVQPAQIRIGGGLGAALAPLPGRVARRLAATARPGRPL
                     PEVGPAVHGPHSSLAGAALLAARGPHVLNGADLFHEGSPP"
     gene            10730..11602
                     /locus_tag="IE189_RS15735"
                     /old_locus_tag="GCM10010496_32150"
     CDS             10730..11602
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF025025.4"
                     /locus_tag="IE189_RS15735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32150"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_189921971.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.8e-23,
                     bitscore: 78.0, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRPAVSVVVPTRDKADSLRLTLACLARQACPEPHEIVVVDDGCT
                     DGTADVVAAAAARLPLRTVPGPRAGRAAARNAGAAAARGGLLLFLDDDILLPPSALAAH
                     LSEHTDREPGCVHGPVRELPAARRLLAAAREESVPDPHGAAMGGRFGRTVTNALEALVT
                     SMGTGGLEPVAPWLTCIGANTSMPYGLWERSGGFDESFGTTWGCEDLELGLRLWSSGAG
                     MRLAPGAPGVHLTHERADRWEQHTINLARFTEKHPVPAVRALPELLGPSGNGLRYVTAV
                     RTLEESSRA"
     gene            11599..12999
                     /locus_tag="IE189_RS15740"
                     /old_locus_tag="GCM10010496_32160"
     CDS             11599..12999
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_Starter (14-311). E-value:
                     6e-32. Score: 103.1. Matches aSDomain:
                     nrpspksdomains_IE189_RS15740_Condensation_Starter.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129809.1"
                     /locus_tag="IE189_RS15740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32160"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_189921973.1"
                     /sec_met_domain="Condensation (E-value: 3.4e-23, bitscore:
                     76.8, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHQARSGRSAGSAPLPLFSRQDWCWEWTRSYTGDSTPIESAETL
                     LFQGPLDTGALRDTLAEIAARHEALRLHLVAKPGPDPSAVWPGQGLRPDAGPLDLVRAA
                     PAERTAEVTRVLSQPLDLTDRMSRTTLVRTGPEEHVLVAQFHHLVFDGTSHRLFRDLLA
                     EGYRARVAPGEDTAKRRADPAGYTDLISQEHTPEVRSAVQGRAAALAGELRAYGAADPL
                     AGDAGAVVAAAEFGSLPVALTAERTRLLLRRSRAERVTLHTVLLAALGHAVATEYERDR
                     LVCSVYTHGRTFASARETLGLFSTVVPVPLDTGYRSPREFLKAVHGSVQRASDRADLPL
                     SEIASRVQDRPPGEGAYYRSAMAHLELRLSGVTGWLPEERNPVPVMPSGLALTPQDLYP
                     EHPAPVFAGPEQALACASTLFADLEVADGALTGSLWYEKHYHDASRATRVGETFMHFIE
                     RVSAGDVL"
     aSDomain        11641..12531
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS15740_Condensation_Start
                     er.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="6.00E-32"
                     /label="IE189_RS15740_Condensation_Starter.1"
                     /locus_tag="IE189_RS15740"
                     /protein_end="311"
                     /protein_start="14"
                     /score="103.1"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLVFDG"
                     /tool="antismash"
                     /translation="PLPLFSRQDWCWEWTRSYTGDSTPIESAETLLFQGPLDTGALRDT
                     LAEIAARHEALRLHLVAKPGPDPSAVWPGQGLRPDAGPLDLVRAAPAERTAEVTRVLSQ
                     PLDLTDRMSRTTLVRTGPEEHVLVAQFHHLVFDGTSHRLFRDLLAEGYRARVAPGEDTA
                     KRRADPAGYTDLISQEHTPEVRSAVQGRAAALAGELRAYGAADPLAGDAGAVVAAAEFG
                     SLPVALTAERTRLLLRRSRAERVTLHTVLLAALGHAVATEYERDRLVCSVYTHGRTFAS
                     ARETLGLFSTVVPVPL"
     CDS_motif       11731..11814
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS15740_0001"
                     /evalue="5.00E-09"
                     /label="C2_LCL_024-062"
                     /locus_tag="IE189_RS15740"
                     /protein_end="72"
                     /protein_start="44"
                     /score="28.6"
                     /tool="antismash"
                     /translation="LLFQGPLDTGALRDTLAEIAARHEALRL"
     CDS_motif       12031..12096
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS15740_0002"
                     /evalue="4.00E-04"
                     /label="C3_LCL_132-143"
                     /locus_tag="IE189_RS15740"
                     /protein_end="166"
                     /protein_start="144"
                     /score="13.1"
                     /tool="antismash"
                     /translation="FHHLVFDGTSHRLFRDLLAEGY"
     CDS_motif       12445..12525
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS15740_0003"
                     /evalue="2.90E-04"
                     /label="C5_starter_265-294"
                     /locus_tag="IE189_RS15740"
                     /protein_end="309"
                     /protein_start="282"
                     /score="13.4"
                     /tool="antismash"
                     /translation="VCSVYTHGRTFASARETLGLFSTVVPV"
     gene            13317..14633
                     /locus_tag="IE189_RS15745"
                     /old_locus_tag="GCM10010496_32170"
     CDS             13317..14633
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_LCL (10-280). E-value:
                     7.6e-37. Score: 118.9. Matches aSDomain:
                     nrpspksdomains_IE189_RS15745_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="IE189_RS15745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32170"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_189921975.1"
                     /sec_met_domain="Condensation (E-value: 1.8e-27, bitscore:
                     90.8, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRANGSAYATELSRQQQRLWEVECLVRGTALLHTGIALRLEGIL
                     DEKRLSHAVTAVFRRHELLNTGFRADCETPVLGPATHDEPHVLHRPDLCADRAADLAEV
                     RRAAAEAHAEMFPLDGGPLARAHLTLLGDGSGVLLLTFHRLVMDLFSLHQVVTDVQEAY
                     RLGPDEPFPPADRYSALLAAREHRRATDWEFWRTELSQFPTPWIAERRPQPGWLPEGAE
                     LRVPLDATLSGLIQANARAARCTPTVYVTAAAAGRVLERSGAADLVLGTMSANRMNSDA
                     VGPLAQAVLVRVGSSAPHGDQGVLAQVRRGLREGIAHQGVEFEEIVDLLTDGMGVARDD
                     LAPLSVSVTADSWQGSVAGLAFTLFDLDDDGGAGQAEEEAEGEAAAGPVVRPSQLDLEF
                     NLSAAQPQLVVTYDRQCFGAPWCERFAADLLTDLATGHG"
     aSDomain        13347..14156
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS15745_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="7.60E-37"
                     /label="IE189_RS15745_Condensation_LCL.1"
                     /locus_tag="IE189_RS15745"
                     /protein_end="280"
                     /protein_start="10"
                     /score="118.9"
                     /specificity="C activity: inactive"
                     /specificity="Active site motif: HRLVMDL"
                     /tool="antismash"
                     /translation="TELSRQQQRLWEVECLVRGTALLHTGIALRLEGILDEKRLSHAVT
                     AVFRRHELLNTGFRADCETPVLGPATHDEPHVLHRPDLCADRAADLAEVRRAAAEAHAE
                     MFPLDGGPLARAHLTLLGDGSGVLLLTFHRLVMDLFSLHQVVTDVQEAYRLGPDEPFPP
                     ADRYSALLAAREHRRATDWEFWRTELSQFPTPWIAERRPQPGWLPEGAELRVPLDATLS
                     GLIQANARAARCTPTVYVTAAAAGRVLERSGAADLVLGTMSANRMNSD"
     CDS_motif       13416..13523
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS15745_0001"
                     /evalue="4.10E-09"
                     /label="C2_LCL_024-062"
                     /locus_tag="IE189_RS15745"
                     /protein_end="69"
                     /protein_start="33"
                     /score="28.8"
                     /tool="antismash"
                     /translation="HTGIALRLEGILDEKRLSHAVTAVFRRHELLNTGFR"
     CDS_motif       13728..13790
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS15745_0002"
                     /evalue="6.70E-03"
                     /label="NRPS-E2"
                     /locus_tag="IE189_RS15745"
                     /protein_end="158"
                     /protein_start="137"
                     /score="9.3"
                     /tool="antismash"
                     /translation="LLLTFHRLVMDLFSLHQVVTD"
     gene            complement(14676..14981)
                     /locus_tag="IE189_RS15750"
                     /old_locus_tag="GCM10010496_32180"
     CDS             complement(14676..14981)
                     /NRPS_PKS="Domain: PCP (21-60). E-value: 9.9e-08. Score:
                     24.1. Matches aSDomain: nrpspksdomains_IE189_RS15750_PCP.1"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012759.4"
                     /locus_tag="IE189_RS15750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32180"
                     /product="phosphopantetheine-binding protein"
                     /protein_id="WP_189921976.1"
                     /transl_table=11
                     /translation="MADVDTSATRDGRQGQDDLTAALAQAWHGVLGSLPAEDSDFYEAG
                     GTSIDAARIASQAAECAPDVEDLDVTLMTALLDEARFADVRRLGLETIDRTRGGVS"
     aSDomain        complement(14802..14918)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS15750_PCP.1"
                     /evalue="9.90E-08"
                     /label="IE189_RS15750_PCP.1"
                     /locus_tag="IE189_RS15750"
                     /protein_end="60"
                     /protein_start="21"
                     /score="24.1"
                     /tool="antismash"
                     /translation="ALAQAWHGVLGSLPAEDSDFYEAGGTSIDAARIASQAAE"
     gene            15118..16524
                     /locus_tag="IE189_RS15755"
                     /old_locus_tag="GCM10010496_32190"
     CDS             15118..16524
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_LCL (9-313). E-value:
                     4.1e-43. Score: 139.5. Matches aSDomain:
                     nrpspksdomains_IE189_RS15755_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129820.1"
                     /locus_tag="IE189_RS15755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32190"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_189921977.1"
                     /sec_met_domain="Condensation (E-value: 7.5e-35, bitscore:
                     115.1, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATSPQPEQGLPLSSRQEWCWEWERCYQEPYPKAVSLDCSTTLR
                     MRGALDVGALREALAEVALRHDALRLRLLDSGTPVERMVRPRQALRAEPFPLELADLGD
                     ALRRRDLHEILVDLTTRPFQVTDRLSRATLLRLAADDHILLTSFHHLVFDEPSHQVYLR
                     DLARFYNRRVAAPGAGGIGASLSYTDFVRTENTRRARLDTATRLAGWADRLRAHGSGDL
                     LPGRTAGFLPLQHQYDSVRLDLSAEETRRLLRAARGERVSLYALLAAALTRTLGGFYGR
                     RQVILSTPSHGRVRPETRSAVGLFSNMIQIPVDLGQHSPSGLFRRVDSVLRDASAVVDL
                     PFGRLAEAVLGREGDAAFYRHALAHAELRLYGVTGWIVDRRQHDISLHGLRTGLVPYQQ
                     DFSRLKYAAPQSSLAAAATLSVGLTMETGRLTGALRYETTYHGRRTAETLADDFRGRLT
                     DLARVGARHA"
     aSDomain        15145..16056
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS15755_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="4.10E-43"
                     /label="IE189_RS15755_Condensation_LCL.1"
                     /locus_tag="IE189_RS15755"
                     /protein_end="313"
                     /protein_start="9"
                     /score="139.5"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLVFDE"
                     /tool="antismash"
                     /translation="QGLPLSSRQEWCWEWERCYQEPYPKAVSLDCSTTLRMRGALDVGA
                     LREALAEVALRHDALRLRLLDSGTPVERMVRPRQALRAEPFPLELADLGDALRRRDLHE
                     ILVDLTTRPFQVTDRLSRATLLRLAADDHILLTSFHHLVFDEPSHQVYLRDLARFYNRR
                     VAAPGAGGIGASLSYTDFVRTENTRRARLDTATRLAGWADRLRAHGSGDLLPGRTAGFL
                     PLQHQYDSVRLDLSAEETRRLLRAARGERVSLYALLAAALTRTLGGFYGRRQVILSTPS
                     HGRVRPETRSAVGLFSNMIQIPV"
     CDS_motif       15238..15333
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS15755_0001"
                     /evalue="5.40E-10"
                     /label="C2_LCL_024-062"
                     /locus_tag="IE189_RS15755"
                     /protein_end="72"
                     /protein_start="40"
                     /score="31.7"
                     /tool="antismash"
                     /translation="STTLRMRGALDVGALREALAEVALRHDALRLR"
     misc_feature    15385..15387
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS_motif       15547..15612
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS15755_0002"
                     /evalue="4.90E-04"
                     /label="NRPS-E2"
                     /locus_tag="IE189_RS15755"
                     /protein_end="165"
                     /protein_start="143"
                     /score="12.8"
                     /tool="antismash"
                     /translation="LLTSFHHLVFDEPSHQVYLRDL"
     CDS_motif       15967..16044
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS15755_0003"
                     /evalue="3.90E-07"
                     /label="C5_LCL_267-296"
                     /locus_tag="IE189_RS15755"
                     /protein_end="309"
                     /protein_start="283"
                     /score="22.5"
                     /tool="antismash"
                     /translation="VILSTPSHGRVRPETRSAVGLFSNMI"
     CDS_motif       16243..16302
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS15755_0004"
                     /evalue="1.10E+01"
                     /label="C2_dual_024-063"
                     /locus_tag="IE189_RS15755"
                     /protein_end="395"
                     /protein_start="375"
                     /score="-1.2"
                     /tool="antismash"
                     /translation="WIVDRRQHDISLHGLRTGLV"
     gene            complement(16531..18321)
                     /locus_tag="IE189_RS15760"
                     /old_locus_tag="GCM10010496_32200"
     CDS             complement(16531..18321)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_LCL (64-309). E-value:
                     2.2e-30. Score: 97.7. Matches aSDomain:
                     nrpspksdomains_IE189_RS15760_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="IE189_RS15760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32200"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_189921989.1"
                     /sec_met_domain="Condensation (E-value: 1.6e-26, bitscore:
                     87.8, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDHPVTEPVHVEFDAATSGAADLTWSQDQVCRWMENSAPYTDHMN
                     LDALIVCEAGTRPTLDDVLGALRVVIERHESLRTRLNVREDGSYRQFVCASGRVPVRVH
                     HRAAPEAVGAVLEELRRLPFTVFEWPLRIAVITVSGVVSAVALCLSHVATDGWGVQVIA
                     GDLRELLTAAPEERASLSARPPRPLLQPREHAAAQRRAGGRSEARADAFWTAQLSRFPN
                     DRFPLTLRTPGSPRFPKTTMRSRSAARALAQAAARHGTTANAVLTGALAVLVSAISGLE
                     DATFRLFCANRTSPASRNSVGTFFQIIPVALTVADLPFRDIAHAAWQASLRAYRVGERD
                     PRRLDLLTESVASARGVDLDLECFLNIHGYGDPGQDRGPTAQDTADEPTVFQDDGGFEE
                     WEPGKFYVDVWRVSGCLEVTLSADTALFSRDRLTAFLACLEEILLRAARDDAPRPQDLV
                     RDAQALAGLDRRAGLELVDGCWIDPAEVRTLLTRALSPRAALVFVEPGGTGSPRLTAYL
                     VPRGPQRPPGPPEMHRLVLAALPGHRFVMAPHRYVVCGAGPSLPATVEEWRGCEVLVEG
                     PGRETPDARSTDATGAGTGA"
     CDS_motif       complement(17392..17454)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS15760_0002"
                     /evalue="2.40E-04"
                     /label="C5_starter_265-294"
                     /locus_tag="IE189_RS15760"
                     /protein_end="310"
                     /protein_start="289"
                     /score="13.7"
                     /tool="antismash"
                     /translation="ANRTSPASRNSVGTFFQIIPV"
     aSDomain        complement(17395..18129)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS15760_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="2.20E-30"
                     /label="IE189_RS15760_Condensation_LCL.1"
                     /locus_tag="IE189_RS15760"
                     /protein_end="309"
                     /protein_start="64"
                     /score="97.7"
                     /specificity="C activity: active"
                     /specificity="Active site motif: SHVATDG"
                     /tool="antismash"
                     /translation="GALRVVIERHESLRTRLNVREDGSYRQFVCASGRVPVRVHHRAAP
                     EAVGAVLEELRRLPFTVFEWPLRIAVITVSGVVSAVALCLSHVATDGWGVQVIAGDLRE
                     LLTAAPEERASLSARPPRPLLQPREHAAAQRRAGGRSEARADAFWTAQLSRFPNDRFPL
                     TLRTPGSPRFPKTTMRSRSAARALAQAAARHGTTANAVLTGALAVLVSAISGLEDATFR
                     LFCANRTSPASRNSVGTFFQIIP"
     CDS_motif       complement(17815..17871)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS15760_0001"
                     /evalue="1.30E-03"
                     /label="C3_LCL_132-143"
                     /locus_tag="IE189_RS15760"
                     /protein_end="169"
                     /protein_start="150"
                     /score="11.5"
                     /tool="antismash"
                     /translation="HVATDGWGVQVIAGDLREL"
     gene            18594..19886
                     /locus_tag="IE189_RS15765"
                     /old_locus_tag="GCM10010496_32210"
     CDS             18594..19886
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF017760.4"
                     /locus_tag="IE189_RS15765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32210"
                     /product="MFS transporter"
                     /protein_id="WP_189921991.1"
                     /transl_table=11
                     /translation="MTDGLAARLPLDLLREPNLRRLFCAQAASVLGSSMMPIALSFAVL
                     EHGGGASGVGLVLGAQTAPLIVFLLAGGVLADRWGRRVTMIGSDLARAAIEIAVVVILL
                     TVGMPLGGFVVFAAALSVAAAFFHPAFHGFVPEVVSGKRLQEANALGSTFNSIGSLLGP
                     AVAGALVAWTDPAWVIAIDAATFLASALFLAGVRTSSSAARSSGEDESFFQQLHHGWRE
                     FSSRTWLWSLLAYTSLASTFVLGPVMVLGIAFVGGKENGAAQWGTVMAAQGVGSLLGGF
                     AGMRVRFRRPLLASVFCTFGLGAFAGLLAVRAPVYVLVLGSLLSGAGFALLHILWTSSL
                     QADVPPDAMSRVSAYDGVATVLSMTVGYWWAAPTADRVGATSLLWFGVVWTLVSAAAMV
                     TLPQIRRSAPGTDKREADAATPEAREPSTTH"
     gene            20001..23078
                     /locus_tag="IE189_RS15770"
                     /old_locus_tag="GCM10010496_32220"
     CDS             20001..23078
                     /NRPS_PKS="Domain: AMP-binding (8-405). E-value: 1.1e-75.
                     Score: 246.7. Matches aSDomain:
                     nrpspksdomains_IE189_RS15770_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (516-578). E-value: 1.4e-11.
                     Score: 36.5. Matches aSDomain:
                     nrpspksdomains_IE189_RS15770_PP-binding.1"
                     /NRPS_PKS="Domain: Condensation_LCL (621-900). E-value:
                     4.2e-26. Score: 83.6. Matches aSDomain:
                     nrpspksdomains_IE189_RS15770_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012711.4"
                     /locus_tag="IE189_RS15770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32220"
                     /product="AMP-binding protein"
                     /protein_id="WP_189921993.1"
                     /sec_met_domain="AMP-binding (E-value: 2.4e-77, bitscore:
                     254.9, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.9e-09, bitscore:
                     32.1, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 9.9e-25, bitscore:
                     81.9, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPADVYAMFRVQAERHPGRTALRQGAEGRTYRELHLFAEELAGRL
                     YRRGVRPGTSVAVHIERGIHAVGALLAVLRLGAAYVPLDVHHPPERSRGALRESGATCV
                     LVCGEAPFEDVEAVDLLRPKPREEVPATAPSPALDDPAYILFTSGSTGVPKGARLPYRA
                     LSNLVTWLRRKASVGVGDRTLQFSRVSFDVFLTEVLGTLATGGELLVLDESRRADLDHL
                     LRFCDDRHIKRLHLPYAALRPFAEWAQYRRASLPHLVEISTAGEQPHVTDALERLLGAG
                     GRPIRLTNQYGPTETHVVTEAILTGDPAGWPRTPSAGVALDNTVVALLDPAGAVVPLGD
                     EGEVSVVGAQVGLGYVGPVSTASGAGFGHVEALGGRWGYRTGDLGRIEDGELVLRGRID
                     HQVKISGHRVEPGEIEILADRAASLAEVAAVPVDTPGGTRTMALFVVPAPGATVDPDAL
                     RGALARRLPEALVPSRIVLCEALPRTSSGKIDRRSLAERHADRTARSAPSSALPAEETR
                     IAGRLAAVLGLDRVLETDSLLSLGGSSLQAMTLLTELAAEFGSTPSMERLMGGASVSDL
                     AGQLRAGGWEEPDSRPPHEANDSVPLVPCDPAAAAGPPGRTPTSLLPASPVQSEIWLAG
                     RLGDPTAHNVTLVLDIAGRLDDARLRHALRHTIARHPALRSLLKRKRDRVFVHRPQDWV
                     TPFAFEAADGAASRTGAEASERAFAERPFDVGSDLPIRVALLRGPGRDRLLVAFHQHAV
                     DAQGIQAFVDDLAHRYGTPDDARADVTDEALDAAAPGPGPADAATLAHWRSALAGVTPA
                     HTTWLRREGGSPSGRSVHRRLELPYDVLHPHRGASGSGTATRFARIIGAFAHAAHAVGA
                     PDEFLTGVVTTRRVPGVSPAVGCHLGLLPILLRPGAGLSDTVTSVHAAMATALSHRQIS
                     LGELTSVLPKGAAVTSTFGLDDAERREVDFAGTRATTRYVHARTLQFPLAFTPWTSPLG
                     TAGLDAVFDDGLHLPDTVDALLDEWTRILRHSAQRP"
     aSDomain        20025..21215
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS15770_AMP-binding.1"
                     /evalue="1.10E-75"
                     /label="IE189_RS15770_AMP-binding.1"
                     /locus_tag="IE189_RS15770"
                     /protein_end="405"
                     /protein_start="8"
                     /score="246.7"
                     /specificity="substrate consensus: Pro"
                     /tool="antismash"
                     /translation="FRVQAERHPGRTALRQGAEGRTYRELHLFAEELAGRLYRRGVRPG
                     TSVAVHIERGIHAVGALLAVLRLGAAYVPLDVHHPPERSRGALRESGATCVLVCGEAPF
                     EDVEAVDLLRPKPREEVPATAPSPALDDPAYILFTSGSTGVPKGARLPYRALSNLVTWL
                     RRKASVGVGDRTLQFSRVSFDVFLTEVLGTLATGGELLVLDESRRADLDHLLRFCDDRH
                     IKRLHLPYAALRPFAEWAQYRRASLPHLVEISTAGEQPHVTDALERLLGAGGRPIRLTN
                     QYGPTETHVVTEAILTGDPAGWPRTPSAGVALDNTVVALLDPAGAVVPLGDEGEVSVVG
                     AQVGLGYVGPVSTASGAGFGHVEALGGRWGYRTGDLGRIEDGELVLRGRIDHQVKIS"
     aSModule        20025..21734
                     /complete
                     /domains="nrpspksdomains_IE189_RS15770_AMP-binding.1"
                     /domains="nrpspksdomains_IE189_RS15770_PP-binding.1"
                     /locus_tags="IE189_RS15770"
                     /monomer_pairings="Pro -> Pro"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       20211..20252
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS15770_0001"
                     /evalue="6.90E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="IE189_RS15770"
                     /protein_end="84"
                     /protein_start="70"
                     /score="16.1"
                     /tool="antismash"
                     /translation="LAVLRLGAAYVPLD"
     misc_feature    20220..20222
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS_motif       20424..20471
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS15770_0002"
                     /evalue="4.00E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="IE189_RS15770"
                     /protein_end="157"
                     /protein_start="141"
                     /score="22.5"
                     /tool="antismash"
                     /translation="AYILFTSGSTGVPKGA"
     CDS_motif       21009..21086
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS15770_0003"
                     /evalue="6.00E-03"
                     /label="NRPS-A_a6"
                     /locus_tag="IE189_RS15770"
                     /protein_end="362"
                     /protein_start="336"
                     /score="9.1"
                     /tool="antismash"
                     /translation="PLGDEGEVSVVGAQVGLGYVGPVSTA"
     CDS_motif       21186..21245
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS15770_0004"
                     /evalue="2.10E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="IE189_RS15770"
                     /protein_end="415"
                     /protein_start="395"
                     /score="32.6"
                     /tool="antismash"
                     /translation="GRIDHQVKISGHRVEPGEIE"
     CDS_motif       21270..21299
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS15770_0005"
                     /evalue="3.00E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="IE189_RS15770"
                     /protein_end="433"
                     /protein_start="423"
                     /score="-0.8"
                     /tool="antismash"
                     /translation="LAEVAAVPVD"
     aSDomain        21549..21734
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS15770_PP-binding.1"
                     /evalue="1.40E-11"
                     /label="IE189_RS15770_PP-binding.1"
                     /locus_tag="IE189_RS15770"
                     /protein_end="578"
                     /protein_start="516"
                     /score="36.5"
                     /tool="antismash"
                     /translation="RIAGRLAAVLGLDRVLETDSLLSLGGSSLQAMTLLTELAAEFGST
                     PSMERLMGGASVSDLAG"
     aSDomain        21864..22700
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS15770_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="4.20E-26"
                     /label="IE189_RS15770_Condensation_LCL.1"
                     /locus_tag="IE189_RS15770"
                     /protein_end="900"
                     /protein_start="621"
                     /score="83.6"
                     /specificity="C activity: inactive"
                     /specificity="Active site motif: HQHAVDA"
                     /tool="antismash"
                     /translation="LPASPVQSEIWLAGRLGDPTAHNVTLVLDIAGRLDDARLRHALRH
                     TIARHPALRSLLKRKRDRVFVHRPQDWVTPFAFEAADGAASRTGAEASERAFAERPFDV
                     GSDLPIRVALLRGPGRDRLLVAFHQHAVDAQGIQAFVDDLAHRYGTPDDARADVTDEAL
                     DAAAPGPGPADAATLAHWRSALAGVTPAHTTWLRREGGSPSGRSVHRRLELPYDVLHPH
                     RGASGSGTATRFARIIGAFAHAAHAVGAPDEFLTGVVTTRRVPGVSPAVGCHLGLLP"
     CDS_motif       21921..22028
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS15770_0006"
                     /evalue="5.70E-11"
                     /label="C2_LCL_024-062"
                     /locus_tag="IE189_RS15770"
                     /protein_end="676"
                     /protein_start="640"
                     /score="34.8"
                     /tool="antismash"
                     /translation="TAHNVTLVLDIAGRLDDARLRHALRHTIARHPALRS"
     gene            23176..24069
                     /locus_tag="IE189_RS15775"
                     /old_locus_tag="GCM10010496_32230"
     CDS             23176..24069
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005473964.1"
                     /locus_tag="IE189_RS15775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32230"
                     /product="RNA polymerase sigma-70 factor"
                     /protein_id="WP_189921995.1"
                     /transl_table=11
                     /translation="MIDATDEQDPYIEHRRLLFATAYRMLGSVTDAEDVLQDTWLRWRT
                     VDRHDLRHPKAYLVRTVTNLSLDRLTSARAVREVYVGPWLPEPLLTSPDVAADTELADS
                     VSTAMMVVLETLSPVERAVFLLREVFAYSHAEIAQTLERPEPTVRQIAHRARDHVQARR
                     PRFDADRNQRRKVTTHFMEACAGGDLNAVMELLAPDVTAWSDGGGKVTAARRPLHGADH
                     VARWITGFLAKPGLADLTMEPVVVNGELGILATLGGHPVGAITFDIADERIQNLRFQVN
                     PEKLSGLTPRNGWTLP"
     gene            24513..27821
                     /locus_tag="IE189_RS15780"
                     /old_locus_tag="GCM10010496_32250"
     CDS             24513..27821
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020126306.1"
                     /locus_tag="IE189_RS15780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32250"
                     /product="RHS repeat-associated core domain-containing
                     protein"
                     /protein_id="WP_189922201.1"
                     /transl_table=11
                     /translation="MVSATLALSALPTAFAVADDTKPGSVWGPGGPDFEVPAVKVGSNR
                     PVKTEPSRNPTDEAYASWLREQREHAEGTPSAKAGPRSGAADTSATSLVPEGQGDVPWH
                     RYTSFAVTDALTAKIDYSTGNLMLTATDFDIAGVGQRLTLARTYNSLDAPWGKVSQRWW
                     QQYERYLHLSSTEAVLYDASGATVRFTKHSDGSFTTPKGWSEDLKKNADGTYTLTKWKS
                     GASDTYDANGTLTKATDRNKGTITVTQHDEGGEHKGFKLTETRSGRWIDLLRTDASQWQ
                     AKDNTGRTAVFGLDGAGNLATTTDTEGKTVTFRHDTSGRIDKITTAEGRVTVFTYDDAD
                     RVTSMLRGTGFDSDGHTGPTWTYGYTGDSATAAGTTTATDPENHATKYAHDGDGQVTEV
                     TDALGHQRSTKFDVNHNIDTATDAMGSGTTPGNVTDYGFDSRNNLKTATLPTGGATVNT
                     WQTIAGGDVPKDSTDPDGEKTAFTYDTAGNTKTVAQTGTGGGSVSYDHNPATASCGGFE
                     GQRCAQKTKMSSSKTVQTDFHYDAKGNLEWAKAPAPLGRTTYTYDDLGRTRTVTDARGV
                     TVTYTYDNLDRIRTVTSPNTVKVEYWYDGDGNLRQRSDNTGTVSYEFDPLQRETVRHLQ
                     DGSQTLLSYTAAGNVDSYQDPAGTVTYTWNEVDKLKELKDSQGRVTSYTYDNNDVRRTT
                     TYPGGTVQTVEVDKSSRPKSLKVTSDQGTLVNLAYTYGYGTGSATDGNKIRTSTDGVTG
                     LKRTYTYDGAGRFSYAKEEKAGAIADSWQYCYDLAGNLTSQGTDPGCPRGTTYTYNDAQ
                     QLTNKSTTTGTWSYDAVGNETAGASTDDYLRTGETWSDHSQMTSITVGGKTYAGQYGST
                     DQRERIRLGDTFFHNGPLGLSAKTTAGTDMGFNREPGGTLNSMTTGGKTYFYLTDAIGS
                     VIGLADEDGNKVDTYAYSPRGVRILAQSSEPVAQPYRFAGNYQDPTGLYHLKARYYDAN
                     TGRFTQPDPSGREQNPYLYAEGDPVNRIDPDGLFSLGGIGDGLGVATILYEGFTGGTGA
                     AEKATAAMIADIGITGLCEAGAAAFTGPGAVPALPFCMTIGAAAGTYIGATYKS"
     gene            27898..28080
                     /locus_tag="IE189_RS15785"
                     /old_locus_tag="GCM10010496_32260"
     CDS             27898..28080
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE189_RS15785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010496_32260"
                     /product="hypothetical protein"
                     /protein_id="WP_189921996.1"
                     /transl_table=11
                     /translation="MIQPGRGRQILLFGMLALVCGVLLLALSSGGPATAFGWLLVAGGA
                     LCVPVSLLSRKKGQG"
     gene            28080..28199
                     /locus_tag="IE189_RS15790"
     CDS             28080..28199
                     /GO_component="GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014158222.1"
                     /locus_tag="IE189_RS15790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LPXTG cell wall anchor domain-containing protein"
                     /protein_id="WP_229901273.1"
                     /transl_table=11
                     /translation="MWSLAAPPPLRDGQSALWFTVGFLVLVGVALFVFSRRNR"
     gene            complement(28302..29063)
                     /locus_tag="IE189_RS15795"
                     /old_locus_tag="GCM10010496_32270"
     CDS             complement(28302..29063)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231: carboxyvinyl-carboxyphosphonate"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010072875.1"
                     /locus_tag="IE189_RS15795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32270"
                     /product="isocitrate lyase/phosphoenolpyruvate mutase
                     family protein"
                     /protein_id="WP_189922000.1"
                     /sec_met_domain="PEP_mutase (E-value: 4.9e-61, bitscore:
                     201.0, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDSRITVERAQRLRQLHAEYKPLVLPTVWDVWSARTAASLGFPAL
                     TIGSHPLADSRGADDHEGQTFEEVLAAVRPIIAAVDVPVSVDLEAGYGHKPADLIAGLI
                     EVGGAGLNIEDTVHSDGGRVRSTEEHASYIGGLRAAADDAGVPIWVNGRTDLFIHAPSA
                     SGVLDEAIERLRALEQAGADSVYPVGIQDDDELLTAVTGAVAVPVNSTAHPVKHDLERF
                     RRLGVGRVTYGPLLQFAMSDAMKDMLGPWTP"
     gene            complement(29213..29875)
                     /locus_tag="IE189_RS15800"
                     /old_locus_tag="GCM10010496_32280"
     CDS             complement(29213..29875)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019059497.1"
                     /locus_tag="IE189_RS15800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32280"
                     /product="response regulator transcription factor"
                     /protein_id="WP_189922002.1"
                     /transl_table=11
                     /translation="MPVTVLLVDDEPLVRMGLRAVLEAQPDIRVVGEAADGAAVIPLVR
                     QLRPDVVAMDVRMPLMDGIEATRAVLRSVAEPPKILVVTTFESDEYVYEALRAGANGFL
                     LKRARAAEIVHAVRLVAEGDSLLFPASVRQLAAEYGDRGGNAAAQDTLRRAGLTERESE
                     VLRLMARGMSNAEIAARLVVGTETVKSHAGAVLAKLGARNRTQAVITAYESGFVAPG"
     misc_feature    complement(29828..29845)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     gene            complement(29890..31044)
                     /locus_tag="IE189_RS15805"
                     /old_locus_tag="GCM10010496_32290"
     CDS             complement(29890..31044)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662028.1"
                     /locus_tag="IE189_RS15805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32290"
                     /product="sensor histidine kinase"
                     /protein_id="WP_189922004.1"
                     /transl_table=11
                     /translation="MGRLLRPLWRGTTYTRLLHLWVPMLVVSVWMFIDPSRPWVPALVL
                     VPVGLIPAVRTGEGVQARLLLVAGDSDPGFSVAPSATWRGRLRTVLWLEVRMVLGAAAA
                     FACVWLPTLAYDLAVGAGGPVPVGLPGPRGAAPRWWTALLVPLPLLALYGAVVGLGRSV
                     TVVARGLLGPSAVERLAALEERTEQLLERNRIARELHDSIGHALTVAVVQAGAARAAGD
                     AKFTDRALAAIEESGRSALADLERVLGVLRESGRPVSESPTLTGADRLLESARASGAKV
                     DAEVSGPLETVPGPVSREGYRILQEALTNVLRHAGPVPVRVRVAVAGDLLYLEVRNPST
                     ARIPGPGRGSGLRGIRERAALLGGRASTGPHEGDWRVRAELPLR"
     gene            31154..32074
                     /locus_tag="IE189_RS15810"
                     /old_locus_tag="GCM10010496_32300"
     CDS             31154..32074
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007380469.1"
                     /locus_tag="IE189_RS15810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32300"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_189922010.1"
                     /transl_table=11
                     /translation="MTSIDVRDLTKEHGPRRAVDRLTFSVRPGRVTGFLGPNGAGKSTT
                     LRLLLGLDRPTAGTATIGGQAYTGLRQPLRHVGALLDAQAAHGSRTGRDHLRALAASNR
                     IPVRRVEDVLTETGLAPAARRRVRTYSLGMRQRLGIAAALLGDPQVVLLDEPSNGLDPE
                     GIVWIRALLKRLAAEGRTVLVSSHLMNETASFADHLVVLGRGRLLADTPLRDFIDARVR
                     PHVRIRTTDPTALKSVLDRHGHDAEEHEDGHWTVHHARVDDIGRLLSDAGVPLLELSAQ
                     EGTLEQAYLDLTAAEAEFTARTQEA"
     gene            32077..32817
                     /locus_tag="IE189_RS15815"
                     /old_locus_tag="GCM10010496_32310"
     CDS             32077..32817
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007380468.1"
                     /locus_tag="IE189_RS15815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32310"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_189922012.1"
                     /transl_table=11
                     /translation="MGFTPALHAEWIKIRTLRSLVGALCAMLSATVVFSALSAFSAGTE
                     TATDGDDLDPLFSALFGVNFGQIAAMAFATTAVSSEFRGGALRLSLAAVPHRGIWFAAK
                     LTAIALPVLTVGLATGLVTVAVGSAVLGEKADALSTADCLRGALGCAAYLTLMALLAAG
                     LTAVLRSGTAALSILVPFLLIVSFVVGDMSGNMADLLPDRAGQVVLHSTWQGTLGPWAG
                     LAVTAAWTATAVAAGTWQLRHRDA"
     gene            complement(32864..33469)
                     /locus_tag="IE189_RS15820"
                     /old_locus_tag="GCM10010496_32320"
     CDS             complement(32864..33469)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010232182.1"
                     /locus_tag="IE189_RS15820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32320"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_189922014.1"
                     /transl_table=11
                     /translation="MSELLVDFITSLDGCASGEGWPGFWGLEGPEYLAWLGTQPKATYL
                     MGTNTYRLMSGFAAGEVPSGQAEFRPEEEASVDELTQATKMVFSSSLEEPLTWANATLV
                     RDDAVKAVRALKASGSGLLSTIGSLSLSKSLLEAGLVDRFRVVMFPVITGATGEERIYD
                     GYPDVALEMIDHRTFDGRIQLVEYKPRVLEHPPLGAPA"
     gene            complement(33634..34014)
                     /locus_tag="IE189_RS15825"
                     /old_locus_tag="GCM10010496_32330"
     CDS             complement(33634..34014)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003983056.1"
                     /locus_tag="IE189_RS15825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32330"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_189922016.1"
                     /transl_table=11
                     /translation="MSGFGPGDSFLADCPARLAVELIADKWTVVVLYGLSRGPVRHGQL
                     IELIGGISRKMLTQTLRRLEAHGLIRRHAYAEVPPRVEYELTPLGATLIDPIHMLTEWA
                     RANGDAVLDALDSAPEPVAQSD"
     gene            34104..35033
                     /locus_tag="IE189_RS15830"
                     /old_locus_tag="GCM10010496_32340"
     CDS             34104..35033
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (16-307). E-value: 1.1e-49.
                     Score: 161.2. Matches aSDomain:
                     nrpspksdomains_IE189_RS15830_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642408.1"
                     /locus_tag="IE189_RS15830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32340"
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_189922018.1"
                     /sec_met_domain="ADH_N (E-value: 3.3e-06, bitscore: 21.7,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.6e-21, bitscore:
                     70.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVITQQTLGGPEVLTVVDAPEPQPFPTEVLVRVKAIGLNPLEAR
                     LRAGEFPLIGRPPFILGWDISGVVEEAPGTWRFRPGDEVFGMPLFPRAASAYAEVVSAP
                     ALHLARKPASLSHVEASALPVVGLTAWQGLVDLGGVKEGDRVLVHGGGGGVGHVAIQIA
                     KALGAYVITTAGGSKRTFVEEFGADEVVDYTAVDFTDAVRDIDVVLDTIGGDTVERSLE
                     VLRPGGHLVTAVAEEDAELIARYEAAGMRFSGIAVQPDPDALRGLVELVEQGRLRVHVQ
                     ETFPFERVAEAHRLLDAGHLQGKLVLTV"
     aSDomain        34152..35024
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS15830_PKS_ER.1"
                     /evalue="1.10E-49"
                     /label="IE189_RS15830_PKS_ER.1"
                     /locus_tag="IE189_RS15830"
                     /protein_end="307"
                     /protein_start="16"
                     /score="161.2"
                     /tool="antismash"
                     /translation="VVDAPEPQPFPTEVLVRVKAIGLNPLEARLRAGEFPLIGRPPFIL
                     GWDISGVVEEAPGTWRFRPGDEVFGMPLFPRAASAYAEVVSAPALHLARKPASLSHVEA
                     SALPVVGLTAWQGLVDLGGVKEGDRVLVHGGGGGVGHVAIQIAKALGAYVITTAGGSKR
                     TFVEEFGADEVVDYTAVDFTDAVRDIDVVLDTIGGDTVERSLEVLRPGGHLVTAVAEED
                     AELIARYEAAGMRFSGIAVQPDPDALRGLVELVEQGRLRVHVQETFPFERVAEAHRLLD
                     AGHLQGKLVL"
     CDS_motif       34530..34592
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS15830_0001"
                     /evalue="1.80E-07"
                     /label="PKSI-ER_m5"
                     /locus_tag="IE189_RS15830"
                     /protein_end="163"
                     /protein_start="142"
                     /score="23.6"
                     /tool="antismash"
                     /translation="GDRVLVHGGGGGVGHVAIQIA"
     gene            complement(35284..36198)
                     /locus_tag="IE189_RS15835"
                     /old_locus_tag="GCM10010496_32350"
     CDS             complement(35284..36198)
                     /NRPS_PKS="Domain: PKS_ER (20-224). E-value: 5e-34. Score:
                     109.7. Matches aSDomain:
                     nrpspksdomains_IE189_RS15835_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014177657.1"
                     /locus_tag="IE189_RS15835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32350"
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_189922020.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 5.1e-13, bitscore:
                     43.9, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVRALVVDPTAPAAVRLAAVCDPTPGPGQVLVAVSHASLNYGDL
                     NDARSGRVPEGAVLGSDSAGVVVQAAADGSGPAVGTRVVALTSGAFAERVAIDVGALAE
                     VPKALDLARAVALPVAGVAALRSLRAAGLGPDKTVLVTGASGGVGRFAVQLAARAGAHV
                     IASVGSAARGKGLAEAGADDVLIGLEGLRRPVDVVIDSVGGPQLVAAWNLLSPGGSVQS
                     VGWTSGEAAVFPPYATVGPAKSLTSFVIEGDVGADLAVLTELAAEGALTVEIGWQGSWD
                     RFNEASRALRERRVSGKAILTVA"
     aSDomain        complement(35527..36138)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS15835_PKS_ER.1"
                     /evalue="5.00E-34"
                     /label="IE189_RS15835_PKS_ER.1"
                     /locus_tag="IE189_RS15835"
                     /protein_end="224"
                     /protein_start="20"
                     /score="109.7"
                     /tool="antismash"
                     /translation="VCDPTPGPGQVLVAVSHASLNYGDLNDARSGRVPEGAVLGSDSAG
                     VVVQAAADGSGPAVGTRVVALTSGAFAERVAIDVGALAEVPKALDLARAVALPVAGVAA
                     LRSLRAAGLGPDKTVLVTGASGGVGRFAVQLAARAGAHVIASVGSAARGKGLAEAGADD
                     VLIGLEGLRRPVDVVIDSVGGPQLVAAWNLLSPGGSVQSVG"
     CDS_motif       complement(35731..35790)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS15835_0002"
                     /evalue="4.50E-06"
                     /label="PKSI-ER_m5"
                     /locus_tag="IE189_RS15835"
                     /protein_end="156"
                     /protein_start="136"
                     /score="19.2"
                     /tool="antismash"
                     /translation="KTVLVTGASGGVGRFAVQLA"
     CDS_motif       complement(35971..36003)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS15835_0001"
                     /evalue="5.70E+00"
                     /label="PKSI-ER_m5"
                     /locus_tag="IE189_RS15835"
                     /protein_end="76"
                     /protein_start="65"
                     /score="0.1"
                     /tool="antismash"
                     /translation="VVVQAAADGSG"
     misc_feature    36267..36282
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.86"
                     /tool="antismash"
     gene            36276..36674
                     /locus_tag="IE189_RS15840"
                     /old_locus_tag="GCM10010496_32360"
     CDS             36276..36674
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019061931.1"
                     /locus_tag="IE189_RS15840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32360"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_189922022.1"
                     /transl_table=11
                     /translation="MSRGHIRVTEALRDEACPVTEVLDRVAGKWSIGILIAAAHGPVRF
                     TELERSINGISRRMLTLTLRRLERDGLLVRTVYPTVPPKVEYTVTPMARELHDSLTGLV
                     GWAERHRSAIAEARAAYDTATEQRPDID"
     misc_feature    36286..36301
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 18.42"
                     /tool="antismash"
     gene            complement(36840..37289)
                     /locus_tag="IE189_RS15845"
                     /old_locus_tag="GCM10010496_32370"
     CDS             complement(36840..37289)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025789.4"
                     /locus_tag="IE189_RS15845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32370"
                     /product="SUKH-3 domain-containing protein"
                     /protein_id="WP_189922024.1"
                     /transl_table=11
                     /translation="MSSWSPRVEAVLKASGWTPGRRVDTSRWRSLFESVGLSMHDAAQA
                     FLQEFGGLTVNVSGPGISCARTPFELDPELAWGEEDRFAQWGEAIGRRLYPLGELDHGR
                     FFLGIDEAGVVHLVETWVAGFGPMPHAMENLVLGVAPRRIDDGGE"
     misc_feature    37354..37365
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            <37399..37527
                     /locus_tag="IE189_RS15850"
                     /pseudo=""
     CDS             <37399..37527
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558180.1"
                     /locus_tag="IE189_RS15850"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="NTVERAINRLKNSRAVATRYDKHGYVFLETVTAAGLVIWLRS"
     gene            complement(37522..37986)
                     /locus_tag="IE189_RS15855"
                     /old_locus_tag="GCM10010496_32390"
     CDS             complement(37522..37986)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018562154.1"
                     /locus_tag="IE189_RS15855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32390"
                     /product="hypothetical protein"
                     /protein_id="WP_229901274.1"
                     /transl_table=11
                     /translation="MIDHGIALPHYRLHVVPAVVALASPTWQREVWLDPDQFEDLNYIV
                     HVLFDDFCDADNPSPWLGQCLRSEEEVELMAGVGTAYSAVQKSVGAAARDEACLVSPGW
                     SAVVAAAARLAQVLVSNDLSALSKLHDAGYRWPLGAESLASETDDPHGES"
     gene            38117..38656
                     /locus_tag="IE189_RS15860"
                     /old_locus_tag="GCM10010496_32410"
     CDS             38117..38656
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE189_RS15860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010496_32410"
                     /product="hypothetical protein"
                     /protein_id="WP_189922026.1"
                     /transl_table=11
                     /translation="MALEGRRTVAICFELVVNFGDDAEAAQVAAQVETKQRVLRADAHR
                     IPLHRPLMAKVGSCFELSILQAAVSWRSALDGGLSRLPLSAAELTELGHQLYDLLAQLR
                     GFVAAKVGWDPESFLDPGELRREWSDELNDGSIHGLVLCEELYAELDLRADYEVFQPGY
                     RWMPYRGEEPSGLIAD"
     gene            complement(38746..39921)
                     /locus_tag="IE189_RS15865"
                     /old_locus_tag="GCM10010496_32420"
     CDS             complement(38746..39921)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386850.1"
                     /locus_tag="IE189_RS15865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32420"
                     /product="cytochrome P450"
                     /protein_id="WP_189922028.1"
                     /sec_met_domain="p450 (E-value: 3.4e-23, bitscore: 76.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDPMKDPRFLQDPYPAYAAIRSTCPVQPVPGPDGHIGYLVTGYT
                     EAREALGDARLSKDTAAFFAGKTSRRRLHPAVAHTMLASDPPRHTRLRALVTKAFTTGA
                     VTRLRPFIARVTDELLDRWPVGEPFDLVDGLAAPLPVLVICELLGVPEEDRADVRRWSA
                     QLFTAGEPEVIDAASHAVAGYMTDLIAAKRREPGDCLLDRLIRARDAEDRLSEDELVSL
                     AALLLVAGHETTTDFLANAVLALLRHPAELDGLRSDPREVPGALDELLRFDSPVSTATF
                     RFTTEALGLGGIDIPAGVPVLVALGAADRDPRRFPEPDRLDLDRDASAHLAFGHGIHRC
                     VGAPLARAETEIALRAVLTRFPTIRLAVTPDQLAWRRTRLLRGPAALPVLV"
     gene            40007..40498
                     /locus_tag="IE189_RS15870"
                     /old_locus_tag="GCM10010496_32430"
     CDS             40007..40498
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009074338.1"
                     /locus_tag="IE189_RS15870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32430"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_189922030.1"
                     /transl_table=11
                     /translation="MRSDVTLHPLDRARLQDLLHAAVEDADPLEVMPPVPGPGGWTTER
                     RSAFVRFHESRSLSAHPVETTFVIAVSGRVVGAARLCPVEDRDGTVEAGVWIGRSHRGT
                     GVGSAVLELLLDRARASGCDEVYVSTTPQNSAVRALMAGIGTELVADGDELVGRVRLTS
                     "
     gene            complement(40637..41320)
                     /locus_tag="IE189_RS15875"
                     /old_locus_tag="GCM10010496_32440"
     CDS             complement(40637..41320)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669805.1"
                     /locus_tag="IE189_RS15875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32440"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_189922032.1"
                     /transl_table=11
                     /translation="MSLILTDVTLTYPDGDSRLTALSGVSLEVPRGSVTAVVGPSGSGK
                     SSLLAVAATLIRPDSGTVTLDGARVTGLSRGELTALRRRGIGIVFQQPNLLPSLTAAEQ
                     LQVMARIDGRSARAARDRARELLDAVGLADRADRRPHELSGGQRQRVNIARALMNEPTL
                     LLVDEPTSALDHERGSSVIDLIARLTRRRGTATVVVTHDHTHLTAADRVAEIHDGRLRL
                     RAERG"
     gene            complement(41317..42405)
                     /locus_tag="IE189_RS15880"
                     /old_locus_tag="GCM10010496_32450"
     CDS             complement(41317..42405)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669804.1"
                     /locus_tag="IE189_RS15880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_32450"
                     /product="ABC transporter permease"
                     /protein_id="WP_189922034.1"
                     /transl_table=11
                     /translation="MFVAWRDLRFAKGRFALMGSVIVLITLLVGLLSGLTAGLGRENVS
                     AITGLPADRIAFQAPDGGRDLSYADSTVTEAQWEQWSEAPGVESAEPLGIATAKGAAGE
                     RSAALSVFGVRPGSRLAPDGDRIGGGAVVLSAAAADDLAVHVGDLLTVAGRRLHVAAVS
                     GDASFSHTPVVWADLDVWRRIAPPSDGEKGPTATVIALATTSAADIRTTDERTGTRTVS
                     TGDSLSAIGSYTSENGSLQLMRALLFAISALVVGAFFTVWTVQRGGDVAVLKALGASTA
                     ALLKDALGQAVVLLAGGTLLGTGIAAAVGALVAGSDVPFLLTPATVLIPAAVMIVLGLS
                     GAALSIRRITSVDPLTALGSAR"
ORIGIN
        1 agctttgtcc tccggagcga acacgcactt tctgttcggc cggaacgagt tggcgttgca
       61 gcatcaccat cgctggttgg accgcctgct tgcagcagcc aaccagtctg acgacaaaga
      121 gttttgagac ttagtcagca tggacagtct ccgacccacc gactagattg tcacccgtcc
      181 gaacgaatga aaggctgtct gtgaaccgcg acgaagtact ccaggagatc caccaaatcg
      241 ccaaggagtt tgccgcctcc agtggtcgca cggtgaacga gaacagcagc aacttcctcg
      301 aggcctatgg attcacctcc ctggacgcac tggagttcct gcttctcctc gaggagcgct
      361 tcggagtgac gttcgaggac gaggacctca cggaggacac gctcacctcc gaagaccggc
      421 tggccgacta cgtcatcgaa cgtctcggct gagcacccgg gagccccgcc ccatgacacc
      481 ccccaagctg acggaagtcg ctgagggatt ctccgtgcac gcggtcagtg cgctggacgc
      541 gcgctttctg taccgcgaga tgttcgaagg cggaacctac gccggtattt ccctccccga
      601 cgagccgttc gtcatcgacg tgggggcgaa catcgggctc ttcacgctct tcgtgaagca
      661 gcgacggccc aaggcgcgca tcgaggcctt cgagccgctg cccgaactcg tcgccgccct
      721 gcacgccaac gtcgcggagt tcgcactcca cgacgtggcc gtgcacgaga cggccctggg
      781 gagcaaggag gcggccggtg tgtccttccg ctactacccg ctgctcccca gcagttcgac
      841 gctgtacccg caggaccagg gtcagctgag ggaactgctg agccagagct ttccgccgcg
      901 ggtcgtggag cggatgttcc agggacgcga gaccaccgtc accgtcgaac ggctctcccg
      961 tcacatcggc accgaccggc ccgtcgatct gctgaagatc gacgcggtgg gttccgaact
     1021 ggagatcctg cggggtatcg acgcggaact gcgccccctg ctgcgcaacg tcgtcatcga
     1081 cgtccaggac gtgcacggcc gggtcgacga actctgctcc tgtctccggg agatgggcat
     1141 ggaacccagc gtcctgaagc cgccgatggc cggcggggag gacacgctga atcatctgat
     1201 ccacgccgtg cgaccgtgac acaagaagtc ctgcgagctc aaagaggggg aacacaggga
     1261 tgctgacgct cggcctgggt gggtccaacc acgacttcgc cgcctgtctc gtctccgacg
     1321 gcgtcatcgc cgcgggtatc gaggaggagc gggtacgtcg ggtcaagtac tcggtcggag
     1381 tcaactcact gttcaacgag tcgtggcggt actgcctcga catggcgcag gcgcgcctcg
     1441 cggacgtcga cgtcatcgtc gccgacgaca cgcttctggc acccgcgtac ttccccttcc
     1501 gcaagcgcat ccacctgata cgccatcaca tggcgcacgc cgccagcacc ttcttcccct
     1561 ctcccttcga acgggccgcc attctcgtgg tcgacggagc gggcagcctg atcgacgacc
     1621 ggggcgtgga gaccctcacc accgccgtcg gcgagggcac caccatcacc gaggtgtcca
     1681 aggtgctcgg caccaactgg tccaccgacg gcctcagcgc ccttcgggtc taccaggccg
     1741 gcgacagcga ccattccctc ggctacatgt acaaagcggt cagcaaggcc atcggcttcg
     1801 tcctgtacga gaacgagtac gagggccgcc actggtacct gtccgaggac ggcaagacga
     1861 tgggcctcgc gccctacggg acctcgcgct actgcaagga gttccgcgag tacctcaccc
     1921 tgctgcccga cggccgctac gaactccacc tcaagaacgg cggactgctc gacttcatcg
     1981 agcacgccct cgacggctac acgggggacg agcgcttcgc ccgcgccgcc gatctcgcct
     2041 acgcggccca ggacacgctg gaggagaccc tcctgcacgt cgcccgccgg ctccacgcgg
     2101 acaccgggct caccgacctg tgcctggccg gcggagtcgc gctgaactgc gtggccaacg
     2161 gccggctgct gcgcgagacc cccttcgaga acgtcttcgt gcagcccgcc gcgggcgacg
     2221 gagggtgcgc cgtcggcaac gcctactacg gctaccacgt catcgccggc cgcccccgcg
     2281 agaagcccgc ccgcaccgcc cagcgccacg cctacctggg ccgcacctac gacgacgggc
     2341 aggtacgggc cgcgctcgac gccagcggac tgccctaccg caaggtcgac gagccctccc
     2401 ggctcggggc ggaactgctc gcgcagggca agctgctggg ctggttcacc ggcggggcgg
     2461 agttcggacc gcgcgccctc ggccaccgca gcatcctggc cgacccccgg cgcgccgaga
     2521 tgaaggacat catcaactcc cgggtcaagc accgtgagcc cttccggccc ttcgccccgg
     2581 ctgtgctgcg cgaacacgcg gccgactact tcgacctcga catcgagtcg ccgtacatgc
     2641 tgatcgtcgc cccggtccgc cccgagaagc agggcgaggt cccggccatc gtgcacgtcg
     2701 acggcaccgc ccgggtgcag accgtgacag ccgaggacaa cggcgcctac cacgggctga
     2761 tcgagcactt ccaccggctg accggagtcc cggtggtgct caacacctcg ttcaacgaca
     2821 acggtcagcc gatcgtcgag accccgcagc aggccctcga gttctacggc ggcagccgac
     2881 tggactggat gatcatcgaa aactacgtgg tggcgcactc ggccgacgac ctggacgccc
     2941 tggcgtccac cctgtcgtcg gcgaccggca gccccgccac cgactgagac cgactgagag
     3001 ggacgcactg tggctctggc actcgacggt ggcaatccgg tccgccgcca cgactttccg
     3061 gcctggccgt accacgacga caccgaacgc gcggcgctgg tccgcgcggt cgaccagggc
     3121 cagtggtggc gagtcggcgg ctccgaggtg acctccttcg aggcggagtt cggcgagtac
     3181 cacggcggca ccacgctcgc cgtcaccaac ggcacccacg ccctggaact gggcctggaa
     3241 ctgctgggcc tcaagccggg cgacgaggtg atcgtgcccg ccttcacgtt catctccacc
     3301 tccatcgcgg tgcagcgcgc gggcggcgtc ccggtcccgg ccgacgtgga ccccgtgacg
     3361 tactgcctcg acccgcagac gctggaggcg gtccgcaccc cgcggacgcg cgtcgtcatc
     3421 ccggtccaca tggccgggca cgtcgccgac atggacgcca tcggagcctg ggccgcccgc
     3481 cacgacatcg tcgtcttcca ggacgccgcg cacgcgcacg gcgccgtctg gtccggccgg
     3541 cgcatcggcg acttcggcac gctcgccgcg ttcagcttcc agaacggcaa gctgatgacc
     3601 gctggggagg gcggggcgct gctcctgccc tcgcaggaat ggttcgacga ggcgttctcc
     3661 cggcacagct gcggccggcc cctcggcgac acggactacg agcaccgcag cccgtcgtcc
     3721 aactaccgca tgacggagtt cgccggggcg gtgctgcgcg cccagctcgc ccggctcgcc
     3781 gagcagaacg cacgccgcga gagccgctgg aagacgctgt ccgcggcact gcgcgagata
     3841 cccggtgtcg tcccgcaggg ccgcgacccg cgctgcgacc tcaaccccca ctacatggcg
     3901 atggccgccc tcgaccccgc ggcgcacccc gggaccgacc gcgacctcgt ggtgaaggca
     3961 ctggtcgccg agggcatccc cgccttcgtc aactacccgc cggtgtaccg cacccgggcc
     4021 cacgaggcgc tgctcggcaa cggactgccg gacacggccg agctcgccga gcgcaacccg
     4081 gtcagcgaac acctgggcgc gaacggcttc tggctgcacc accgggtgct gctcggcacg
     4141 gacgccgact gcgccgacgt cgcggaggcc gtggccaagg tgctgaccga gctggcgggg
     4201 aagaagcgat ccgctcgatg aaggtcgccg tcatcggact gggctgggtg gcccgcgagg
     4261 tatggctgcc ccggctggtc aagcaccccg acttcgacgt cgtcgccgtc gtggagccgc
     4321 ggcccgaggc cgtcgagcgg gccgccgccc tggtgggcgg ggcgcaggtg tacggcgggt
     4381 tccaggagct cgggccgcac gaagccgacc tcgtgttcgt cctcaccccg aaccacaccc
     4441 acggcgcgct cgcgagccac ttcctgcgcc agggcctcgc ggtgttcctg gagaagccca
     4501 ccggcaccga cttcgcccac ctgcggctcc tcgaggacgc cgcccgcgac ggcggagggc
     4561 ggctgctgct gtccaccgcc gcccgccacc gcgcggacgt gggggagctg gcgcgtctcg
     4621 tctccgacgg ggcgctcggc acgccccgcc acgccgagct gagctgggtg cgctcccggg
     4681 gcatccccgg cagcgactgg ttcgcccgcc gcgagacggc cggcggcggg gtcctggtcg
     4741 acctgggctg gcacgtgatc gacgtcctgc accacctgtg gggcgcctcc ggcgtgcgcc
     4801 acgccaccgc ccttgcctcc agcgacttcc tcacccgcgc gggctggggg gcggactggc
     4861 acgcgggcac ggccggcctt gcggacgccg acgtggagga ccagctcacc gccctcgtgg
     4921 tcaccgagcg gtacggcatg cagctgcgct tcgcctgggc ctcgcacgag ccggtcgacc
     4981 gtacccggct ggtgctgcac ggcaccgagg gcaccgccga gctgaccacc acgttcggct
     5041 tcagcccacg acgtgtcgac gaaccgacgc tcacgctccg ccaggagggc gcggaacgcc
     5101 gggtgccgct gcccccggcc ggcgtcggtg acgagtacga ccagcaactc gacgcgctgg
     5161 ccgccgaact ggcccggccc gacgccacgg accgggcgct gcgcgaagca cgcgaggccc
     5221 tggccgtcgt cgaggcctgc taccgcgcca cgtccgcccg ttggacagca ccggagacga
     5281 attcatgact gcatccctgt ccgagcccac ggcgctgcgc tacgagccgc tgcgcggcct
     5341 cgccctgtgg ggcgaggagg agaaggccgc cgcactggac gtgctcgaga gccgctccct
     5401 gttccggtac tacggtcccg cgctccagcg ccgcgtcgag cggttcgagg agcggttcgc
     5461 cgccctgcac cagacacccc acgcggtcgg cgtctcctcc ggtaccgccg ccctgacctg
     5521 cgccctgatc ggcctgggga tccccgaggg cggtgaggtc atcgtgccgt cggccacctt
     5581 catcggctgc gtcaacgcga tcgtggccgc gcgcggcgtc cccgtcttcg ccgacatcga
     5641 cgagtcgctc accctcgacc cgacggcatg ggagaagctc gtcaccgagc ggaccttcgc
     5701 ggtcatgccc gtccacctga acaacgtcgc cgccgacatg gaccccatcc tcgccgtcgc
     5761 ccgcgagcac ggcatccggg tcctcgagga cgccgcccag gcctgcggcg tcagctaccg
     5821 ggggcgcccg gtgggctcga tcggcgacgc gggggccttc agcttccagc tggagaagaa
     5881 catcaccgcg ggcgagggcg gtgccgtcgt gacgacggac cccgaggtgc acgaccgcgt
     5941 ggtccgctac caggaccagg gcgggcagtt caccacctcg cgcagcggcg agcgcggcgg
     6001 agcctcgggc gaggccttcc tcggcgccaa cctgcggatg acggagatcg ccggcgccct
     6061 gctgtccgta cagctggaac ggctcacgcc gatgctgcgc cggctgcgcg acgtcgcccg
     6121 gaccgtccgc gcggacctcg ccgacctgga gctcgagtgg cggcggctgc cggacgagga
     6181 gggcagcggc ggcgatctca cggtcctgct ggccgaccgc atggccgccc gccggttcgt
     6241 caccgtgctc accgccgccg gcatccccgc ggccacgctc tattccggcc gcctcgtcca
     6301 gcagaacccc gccgtccgcg cgggccgcac cccctggggc gtcgcctggg acgccaccgc
     6361 gcgcctgcgt gccagcgagg ccgtgctggg ccggtccgtc accgtcggac tcggcgcgac
     6421 catgacggac gacgacgtcg cccacctggt ggcgagcatg cggacggcgt ccgaagccgt
     6481 ccgaaaggga gcgaaccgtg agtgacctgt ggccgcgggc cgtcgtcctg gatctggacg
     6541 gcgtgctcat cgacagcatc cacgtgatgc gcagggcctt ccagcgggcc tacgacctca
     6601 cggtcggcga gggcgaggca cccttcgagg agtacctgac ccacctcggg cggcacatgc
     6661 ccgacacctt ggcgatcatg gggctgcccg tcgggatgta cgagccgttc gtcgtcgaga
     6721 gccgcaaact ggtccacgag atcgagccct gccccggcgc ggcggaactg ctcgccggac
     6781 tgcgcgaggc cggtgtcccc accgccgtcg ccaccggcaa gacccacggc cgtgcggtgg
     6841 aggcactgtc ggcgaccggc ctgctggacc tggtggacgc ggtgtgcggc agcgacgagg
     6901 tggcgcacgg caagcccgct cccgacatcg tcctgctcgc cctggagaag atcggcgccg
     6961 cagccgacgg cgccgtcatg gtcggcgact ccgcgctgga cctgcgggcc ggccgcgcgg
     7021 ccggcacccg tacggccgcc ggcctctggg gccagggcga ccgggaggaa ctgctcgccc
     7081 accgccccga actggtggcc ggctcgtgcg ccgaactggc cgccctgctg ctccgccgtg
     7141 aagggacccc cgcgtgacca tcgcctcgac ctcccgtgac ctgctgctgc tcaacggccc
     7201 caacctgggc acgctcggca cgcgcgaacc cggcatctac ggcaccacca ccctggccca
     7261 ggtggaggag acggtggccg agctgctggc ccgcgcaggg tacgggctgc gcagcgaaca
     7321 gcacgacggc gagggagagt tgatccgcgc gctgcacaag caccgggaca ccgtcgcggc
     7381 cgtcgtcaat cccggcgcgc tgatgatcgc cggctggagc ctgcgcgacg ccctcgccga
     7441 ctacccggcg ccctgggccg aggtgcacat ctccaacgtc tgggcccgtg agtcgttccg
     7501 gcacaactcc gtcgtctcac ccctcgccgt gggtgtgatc gcgggtttcg gcacccacgg
     7561 gtacgaactc gccgcccagg cactcgtacg gcggctggag tccgcggcgc agggcgaggc
     7621 gaagtgaatg ccgcgaacct gtgggaagcc ttcgcccgag cggacctgga cccggacgcg
     7681 ccggcgctcg gcgacctctc ccgccgggcg gccgtcagcc gggtgaccga gctggccgaa
     7741 cggctgcgcg cccagggcgt acggcccgcg gagaccgtcg gcctccaggg gcccaaccag
     7801 cccgaatggg tactggggct gctcgcgctg acggcggtgg gcgcctgccc cctgctgctg
     7861 cccgcggact cgccaccggc ggagacccgc aggctgctca ggaccgccgg cgcccggcgg
     7921 acgctggtga cggacccggg tgaggcgcac ggtgcggtgc tccggccgca cgacggcggt
     7981 accgacgacg gctccaccgg tgccgggacc ggcgcggtcg acgcggatcc cggtccgtcc
     8041 gcccccgacc cgggcacggt cgtcctggtc tcctccgggt cgaccgggac gcccaagctc
     8101 gtggcacggt cgccgcgttc cgtgctcgac gagggcgtgc gctaccacca cgccggcctg
     8161 gcgcggcggg aggaccgcgt actgcttccg ctgccgctga gccatgccta cgcgctcggt
     8221 tggctggccg gcgcgctggt ggccggggcg cacgtggacc cggtgccgcc gcgcgccgtc
     8281 ggctccgtgc acagcagact gcgcgagggg gcgacggtcc tggtcaccgt gcccggcctg
     8341 gcccgcgtcc tggcgcgccg acgggccctg accgacgacg ccccgttccc cgcgctgcgc
     8401 cgggtgatgg ccggcgcagg atacgtggac gtcgggctcg acgcgctgtg gtcgcgcgct
     8461 ctcggtgtgg gtgtgtcccg caactacggc tccagcgaga cgggtgcggt gctgtgggga
     8521 gagcccggac tgccgtcggg agccgtcggc cgtccgatgc ccggcgtgcg gatcgacctg
     8581 ctggaccccg acggcacgcc ggtgcccggc gggggagcgg cccagggaga gctcgccgtc
     8641 gtcctggagg acggctcggt ccaccgcctg cacgacctcg ccgatcgcga cgaggacggc
     8701 gtccaccgca tcctgggcag ggcccggctc ggcgtggtca gacggggggc ccgctgggtc
     8761 tccaccctgg aggtcgaatc ggtgctccgg gcggcccccg gcgtcgccga cgtctcggtc
     8821 acggcgacgg gtgcgcagga ctcggacgac caggggctca ctgtcgagta cgtccccgcc
     8881 gacaccgaac tggcctcccc ggcgcgggtg caggcctacg cccgtgccga actggccggg
     8941 ttcaaggtcc ccgacagctt cctgccccgc taccggctgc gccgctcggc cgtcggcaag
     9001 acacaggcgg cccccgcgta ccgcctcgcc cggggggccc gcgccgcgac catggccgag
     9061 caggtcctgg cggcggccct caccgaactc ggcctgcccc cgctcctggc ccagggcggc
     9121 accgccgccg acctggccgc gacgacgggc ctgcgcgcgg aggtgctgtc gcccgtgctg
     9181 gacaccgcct gcgcgctggg actgctggtc acggacacct tctcggcggg ggcgccgggc
     9241 gactggacgc tccccccgga cgtcctgccg ggcggccggg cgctggcggc ccgggtgcgc
     9301 ggagaaacgg cgcccgagcg accggacccg cctgccgcgc ccttcgggcc ctcggcggtg
     9361 acgaaggccc tgcgggcgag cgtcgaggcg ctgctcgcgg agaccgccgt cgacggatcg
     9421 ctgctggaga tcggcgacgg cggtgcccca ccggcgaccg atgccgagca cggcgcctgc
     9481 gtggtcctcg ggggtgtcca cggcccggcc gccggactgg gatcgctcgc cgcactgctg
     9541 aggccgaagg gactgctcgt ggtcgccgac gccttcgtcg acgacccgct ggccctcacc
     9601 gacgacatga gccggaccct ggcggtgcgt tggctcgttg acgggcatct gcactggtgg
     9661 acgacgcagg agctccgggc cggactggag gccgtggggc tgcgggtcga ggagagccgg
     9721 cgcgccgagc aggcgccgta cgcgatcgtc gtcgcccgga agccgtcgtg accgacgacc
     9781 gcccgcgccc gcacgcggac accgcgggcg gtgtcctcgc cgtggacatc ggggggacca
     9841 aactggccct gcgcgcggtg gccgccggga cgaccgtgca cgagcgcacc gtgccgtggc
     9901 ccgcgggcga cgacgcggaa gccgattcgg agctgctgga agcgtgcgtc gccgaggcga
     9961 tcgccgcgct accgggagcc cccgtgcgga tcggcgtcgc cgcggcgccc aacgtcggcg
    10021 ccgacgcgac cgtgctgagc tggcccaacc ggccgacctg ggtgggccgt tcgctgagcg
    10081 ccccgttcac cggcagcggc gccgaggtcc tgttcggcga cgacgcgacg ctcgccgcgc
    10141 tggcggaagc cgtgtccacg gccggccggg acctcgccta cctgggcatc ggcacgggtg
    10201 tcggcggcgg gctggtcagc gggggccgac tgctgaccgg cgcctggggc acggcggggg
    10261 agctgggcca cctggtgacc gatccgcgcg gtccgcgctg ccggtgcggc acgcgcggct
    10321 gcctgcaagc cgtggtctcg gccgaggcac tggccgcgca cgccaccgcg gcccgcggac
    10381 tccccacgtc gagcgccgag ttggtggcgg gcgtggagcg cgccgagccg tgggcggagc
    10441 gcaccctcga ccacgcggcc gactcgatcg ccggagcgct gcgggtcctc gcggagctcg
    10501 tccagcccgc gcagatacgt atcgggggcg gcctcggagc cgcgctcgca ccgctgcccg
    10561 gcagagtggc ccgccgcctg gccgcgacgg cccgcccggg ccggccgctc cccgaggtcg
    10621 gcccggccgt ccacggtccg cactcctccc tcgcgggcgc ggccctgctg gctgcccgcg
    10681 gcccacacgt gctcaacggg gcggatctgt tccacgaagg gagcccgcca tgacccggcc
    10741 ggcggtcagc gtggtcgtcc cgacccgcga caaggcggac agcctgcggc tgacccttgc
    10801 ctgcctggcc cgtcaggcgt gcccggaacc ccacgagatc gtggtcgtcg acgacggctg
    10861 caccgacggc accgccgacg tcgtggcggc agccgccgca cggctgcccc tgcgtaccgt
    10921 cccgggaccg cgcgcgggcc gcgccgccgc acgcaacgcc ggggcggccg cggcccgcgg
    10981 cggcctgctg ctcttcctcg acgacgacat cctgctcccg ccctcggccc tggcggccca
    11041 cctgtccgag cacaccgacc gggagcccgg ttgcgtgcac ggaccggtcc gtgaacttcc
    11101 cgccgcccgg cggctgctgg ccgccgcgcg ggaggagtcc gtccccgacc cccacggggc
    11161 ggccatgggc ggccggttcg ggcgcacggt gacgaacgca ctggaagcac tggtgacgag
    11221 catgggcacc ggcggactcg aacccgtggc accctggttg acctgcatcg gcgccaacac
    11281 ctcgatgccg tacgggctgt gggagcgatc cgggggcttc gacgagtcgt tcggtacgac
    11341 atgggggtgc gaggacctcg aactcggcct gcggctgtgg tcgtcgggag cggggatgcg
    11401 cctggctccc ggcgccccgg gagtgcacct cacccacgag cgggccgacc gctgggaaca
    11461 gcacacgatc aacctcgccc gcttcaccga gaaacacccc gtgcccgcgg tacgcgccct
    11521 gccggagctg ctcggcccct cggggaacgg cctccggtac gtcaccgccg tacgcaccct
    11581 ggaagagagc tcccgcgcat gacccaccaa gccaggagcg gccgctccgc cggctccgct
    11641 ccgctgcccc tgttctcccg tcaggactgg tgctgggagt ggacacggag ctacaccggc
    11701 gactcgacgc cgatcgagtc ggccgagacc ctgctgttcc aggggccgct cgacaccgga
    11761 gcactgcggg acaccctggc cgagatcgcc gcccgccacg aggcgctgcg cctgcacctc
    11821 gtggcgaagc cgggaccgga cccgtccgcg gtctggcccg gacaaggact gcggccggac
    11881 gcgggcccgc tggacctcgt acgggccgca ccggcggagc gtacggcgga ggtgacgagg
    11941 gtcctctcac agcccctgga cctgacggac cgcatgagcc gcaccaccct ggtccgcacc
    12001 gggccggagg agcacgtcct cgtcgcgcag ttccaccacc tggtcttcga cggtacgtcc
    12061 caccgcctct tccgggacct gctcgccgaa ggctaccgag cacgcgtcgc cccgggcgag
    12121 gacaccgcca aacgccgtgc ggatccggcg ggttacaccg acctgatcag ccaggagcac
    12181 acgcccgagg tgcgctccgc cgtgcagggg agagccgccg ccctggccgg ggaactgcgc
    12241 gcgtacggcg cggcggaccc gctggcgggg gacgccgggg cggtcgtcgc cgcggcggag
    12301 ttcggttctc tgccggtggc gctgacggcc gagaggaccc ggctgttgct gcgccgctca
    12361 cgcgccgagc gcgtcacgct ccacaccgtc ctgctggccg ccctcggcca cgccgtcgcc
    12421 acggagtacg agcgggaccg tctcgtgtgc tccgtgtaca cgcacggacg gaccttcgcg
    12481 agcgcccgcg agacgctcgg cctgttcagc accgtggtcc ccgtaccgct ggacaccggg
    12541 taccggtcgc cgagggagtt cctcaaggcc gtccacggca gcgtccagcg ggcctcggac
    12601 cgggccgacc tgccgttgag cgagatcgcc tcccgggtcc aggaccgtcc gccgggcgag
    12661 ggggcctact accgcagcgc catggcccac ctggaactgc ggctgagcgg cgtgaccggg
    12721 tggctgccgg aggagcgcaa ccccgtgccg gtcatgccgt ccggcctcgc cctgaccccg
    12781 caggacctgt atccggagca tccggccccg gtcttcgccg gtccggagca ggcgctggcg
    12841 tgcgccagca ccctcttcgc cgacctggag gtcgcggacg gggccctgac gggctccctg
    12901 tggtacgaga agcactatca cgacgcctca cgcgcgacac gcgtcggcga gacattcatg
    12961 cacttcatag agcgagtgag tgcgggcgac gttctatgac ggcacgtcag aattagccgc
    13021 gattaacgtc gttgtccggt ccacacgtat acgcaggaac agcaggacag tgtggcaatc
    13081 cttgttgacg agagatcact tggcctgaaa gcattccact gccaccgacc ggtggccgaa
    13141 gaagtagcct acggaaaggg gaagttgaca tgatcaaggt caactctgtg agcctcgcgc
    13201 tcatcaacct cgagcagctc cgccgtcagg ccgcggcgaa gtagtgctat cgacaagtgc
    13261 cgtacgggag tcgttctttc gtgcggcact tgtcgcaaca ccgggtgagg gagcgcatgg
    13321 accgggctaa tggaagcgcg tacgccacgg aattgagccg ccagcagcaa cggctctggg
    13381 aagtggagtg cctggttcgg ggaaccgcgc tgctgcacac cggcatagcc ctgcgtctcg
    13441 agggaatact cgacgagaaa aggctttccc acgccgtcac cgccgtattt cggcgacatg
    13501 aactgctcaa caccggcttc cgcgcggact gcgagacacc ggtcctcgga ccggccacgc
    13561 acgacgagcc gcacgtcctg caccgtccgg acctgtgtgc cgaccgggcc gcggacctcg
    13621 ccgaggtacg ccgagcggcg gccgaggccc atgcggagat gtttcccctg gacggcgggc
    13681 ccttggcgcg cgcccacctg acgcttctcg gtgacggcag cggcgtcctg ctcctcacct
    13741 tccaccggct cgtgatggac ctgttctccc tgcaccaggt ggtgacggac gttcaggagg
    13801 cctaccggct cggaccggac gagccgttcc cgccggcgga ccgctactcg gcactgctgg
    13861 ccgcgcgtga gcaccgcagg gccaccgact gggagttctg gcgcaccgaa ctgtcacagt
    13921 tccccacccc gtggatcgcc gaacgacgtc cgcagccggg ctggctgccc gaaggcgccg
    13981 agctgcgcgt tcccctcgat gccaccctct ccggtctcat ccaggcgaac gcccgggccg
    14041 ctcgctgcac gcccaccgtg tacgtcaccg ccgcggccgc cgggcgggtg ctggagcgct
    14101 ccggggccgc cgacctggtc ctcggcacca tgtccgcgaa ccgcatgaac tccgacgcgg
    14161 tgggtccgct cgcccaggcg gtcctcgtcc gcgtcggctc ctcggccccg cacggcgacc
    14221 agggcgtgct cgcccaggtg cggcgagggc tgcgcgaggg aatcgcgcac cagggagtgg
    14281 agttcgagga gatcgtcgat ctcctcaccg acgggatggg cgtcgcccgt gacgatctgg
    14341 ccccgctcag cgtgagcgtg acggcggact cctggcaagg ctccgtggcg gggctcgcct
    14401 tcaccctctt cgacctcgac gacgacggtg gcgcagggca ggccgaggag gaagcggaag
    14461 gggaagcggc cgccgggccg gtggtccgcc cctcccagct ggacctggaa ttcaacctgt
    14521 ccgcggcaca acctcagttg gtcgtcacct acgaccgcca gtgcttcggt gcgccatggt
    14581 gcgagcggtt cgcggccgac ctgctgaccg acctggccac cggccacggc tgacgcggcg
    14641 cccgcatccg ggcggacgga tcaccgcccg cccggtcagg acaccccacc ccgtgtgcgg
    14701 tcgatcgtct ccagccccag ccgtcgtacg tccgcgaagc gcgcctcgtc gagaagcgcg
    14761 gtcatcagcg tgacgtccag atcctcgaca tccggcgcgc actccgcggc ctgcgaggcg
    14821 atccgcgccg cgtcgatcga cgtgcctccg gcctcgtaga agtccgagtc ctccgccggg
    14881 agggagccga gcacgccgtg ccatgcctga gcgagggccg ccgtgaggtc gtcctgtccc
    14941 tgccggccgt cccgcgtcgc cgaggtgtcc acatccgcca tggcaggaac ataacgcacc
    15001 ggcgcccatc gcggtccgaa gttttacagt cgtgtggcat gaccgctctg acaaggggat
    15061 acgccgtgcg ccgagggtag cgtcgactgc gttacggcgt cttccccgag gcaggtcatg
    15121 acggcgacat cccctcagcc ggagcaagga cttccgctct cctcgcgtca ggagtggtgc
    15181 tgggagtggg agaggtgtta ccaggagccc tacccgaagg cggtctccct ggactgctcg
    15241 accaccctgc gcatgcgagg ggccctggac gtcggcgcgt tgcgtgaggc gctcgccgaa
    15301 gtcgccctgc ggcacgacgc gttgcggctg cggctgctcg actccggtac gccggtggag
    15361 cgcatggtcc gaccgaggca ggcgttacgc gcggagccct ttcccctgga actggcggac
    15421 ctgggcgacg cactgcggcg acgggacctg cacgagatcc tcgtcgacct gaccacacgg
    15481 cccttccagg tcaccgaccg gctgtcccgg gccaccttgc tgcggctggc cgccgacgac
    15541 cacatcctgc tgaccagctt ccaccatctg gtcttcgacg agccgagcca ccaggtctac
    15601 ctgcgcgacc tcgcccgctt ctacaaccgc cgcgtggccg cccccggtgc cggcggcatc
    15661 ggagcatcct tgtcctacac ggacttcgtc cgcaccgaga acacccgccg agcccgcctc
    15721 gacaccgcga cccgtctcgc cggctgggcg gaccggctgc gggcccacgg ctccggggac
    15781 cttctgccgg gccgcaccgc cggattcctc ccgctccagc accagtacga cagcgtccgt
    15841 ctggacctgt ccgccgaaga gacccgccgg ctgctgcgcg cggcccgcgg tgaacgcgtc
    15901 tccctgtacg cgctgctcgc ggcggcactg acccggaccc tgggcggctt ctacggccgc
    15961 aggcaagtga tcctctccac gccctcgcac ggccgcgtgc gccccgagac ccgctccgcc
    16021 gtcggtctgt tctccaacat gatccagata ccggtggacc tggggcagca ctcgccgagc
    16081 ggactgttcc gccgggtgga cagcgtcctc agggacgcct cggccgtcgt cgatctgccg
    16141 ttcggccggc tcgccgaggc cgtcctgggc cgcgagggcg acgcggcctt ctaccgccac
    16201 gccctcgcgc acgcggaact gcgcctctac ggggtgaccg gctggatcgt cgaccggcgg
    16261 caacacgaca tatccctgca cggactgcgc accggtctcg tcccctacca gcaggacttc
    16321 tcccggctca agtacgccgc accgcagtcc tccctggccg ccgcggccac gctctcggtc
    16381 ggcctcacca tggagacggg ccggctgacc ggcgcgctgc gctacgagac gacgtaccac
    16441 ggacgccgga cggccgagac cctggcggac gacttccggg gacggctgac cgacctggcg
    16501 cgcgtcgggg cgcgacatgc gtgagtcccg tcaggccccg gtcccggctc cggtggcgtc
    16561 ggtggagcgt gcgtcggggg tctcgcgtcc cggcccctcc acgaggacct cgcacccccg
    16621 ccactcctcc accgtggcgg ggagcgaggg gcccgccccg cagacgacgt accggtgcgg
    16681 ggccatgacg aacctgtgcc cgggcagggc ggccagcacc aggcgatgca tctccggcgg
    16741 accgggcggc cgctgcggcc cccggggtac gaggtacgcc gtcagacggg ggctgccggt
    16801 gccgccgggc tccacgaaga ccagcgcggc gcggggggag agcgcccggg tgagcagcgt
    16861 gcgcacctcg gccggatcga tccagcagcc gtccacgagc tccaggcccg cgcgtcggtc
    16921 cagcccggcg agtgcctggg cgtcccggac gaggtcctgc ggccggggcg cgtcgtcgcg
    16981 ggcggcccgc agaaggatct cctccagaca ggcgaggaat gcggtgagcc ggtcgcggga
    17041 gaagagggcg gtgtccgcgg agagcgtgac ctcgaggcat ccggacacgc gccacacgtc
    17101 gacgtagaac ttgcccggct cccactcctc gaagccgccg tcgtcctgga agaccgtggg
    17161 ctcgtccgcc gtgtcctggg ccgtcggccc ccggtcctgg cccggatcgc cgtagccgtg
    17221 gatgttgagg aagcactcca ggtccaggtc cacgccccgg gcggacgcca ccgactccgt
    17281 cagcaggtcg aggcggcgcg ggtcgcgctc gccgacacgg taggcccgca gggacgcctg
    17341 ccacgcggcg tgggcgatgt cgcggaacgg gagatcggcg accgtgaggg ccaccggaat
    17401 gatctggaag aaggtaccga ccgagttgcg gctcgccggt gacgtccggt tcgcgcagaa
    17461 cagccggaac gtggcgtcct ccagtccgct gatcgcgctc accagcaccg cgagggcccc
    17521 ggtcagtacc gcgttggcgg tcgtgccgtg gcgtgcggcg gcctgcgcca gcgcacgtgc
    17581 cgccgaccgg gaacgcatcg tggtcttcgg gaatcgcggg gacccgggag tccgcagcgt
    17641 aagggggaaa cggtcgttgg gaaagcggga gagctgagcg gtccagaagg cgtcggcccg
    17701 ggcctcgctc cggccaccgg cccggcgctg tgccgcggcg tgctcgcgcg gttgcagcag
    17761 cgggcgggga ggccgggcgg acagggaggc acgctcctcg ggagccgccg tcaacagctc
    17821 cctgaggtca ccggcgatca cctggacacc ccagccgtcg gtcgcgacat gggaaaggca
    17881 caacgccacc gcggacacga cgcccgagac ggtgatcacc gcgatacgca gaggccactc
    17941 gaacacggtg aagggaaggc gcctcagttc ctccaggacg gccccgacgg cctcgggggc
    18001 ggcgcggtgg tggacccgga cgggcaccct cccgctcgcg cagacgaact gccggtagct
    18061 gccgtcctcg cgtacgttga gccgcgtccg caacgactcg tgacgctcga tcaccacccg
    18121 gagggccccc agcacgtcgt cgagggtcgg cctcgtgccc gcctcgcaca cgatcagcgc
    18181 gtcgaggttc atgtggtccg tgtacggagc ggagttctcc atccaccggc acacctgatc
    18241 ctgactccag gtgaggtccg cggcccccga ggtggcggcg tcgaactcga cgtggaccgg
    18301 ttcggtcaca gggtgatcca tcgctcggtc tgctcctcgg tcgccggggt cgcacgggac
    18361 ggctggcggg gaccggtcga gcggcgccga ccgtcctccc cggacggctg gaagacaggg
    18421 gtgtgaagat ttttgcggac cggtgatcac ccgttcgaac tcacatattc tgtccggcgt
    18481 cgtgttcgga tacacggagc ccgagtggcg cgatcgcgcc gggcgggccg agagaggagc
    18541 gcacgggtga gtcacgcacg aggtccggcg acggacccga cgggggacac gcgatgaccg
    18601 acggtctggc tgctcgacta ccactggacc tgctgcgcga gccgaatctg cggcggctgt
    18661 tctgcgccca ggccgcctcg gtcctgggca gcagcatgat gcccatcgcc ctgtcgttcg
    18721 ccgtgctgga acacggcggc ggggcgagcg gggtcggcct ggtgctgggc gcgcagaccg
    18781 cgcccctcat cgtgttcctg ctggcgggcg gcgtcctggc ggaccggtgg ggccgcaggg
    18841 tcaccatgat cggcagcgac ctcgcgcgcg cggccatcga aatcgccgtc gtggtcatcc
    18901 tgctgacggt cggtatgccg ctgggaggct tcgtcgtctt cgccgcggcg ctctccgtgg
    18961 ccgccgcgtt cttccacccc gccttccacg ggttcgtccc cgaggtcgtc tcggggaagc
    19021 ggctccagga ggccaacgcc ctgggctcca cgttcaattc gatcggctcg ctgctgggac
    19081 ccgccgtcgc cggagcgctg gtggcctgga ccgatcccgc gtgggtcatc gccatcgacg
    19141 cggcgacctt cctggccagc gcgttgttcc tggccggagt gcgcacctcg tcgtccgctg
    19201 cgcggtcctc cggcgaggac gagagcttct tccagcaact gcaccacggc tggcgcgagt
    19261 tcagctcacg cacctggctg tggtccctgc tcgcctacac ctcgctcgcg tccaccttcg
    19321 tcctggggcc cgtgatggtg ctgggcatcg ccttcgtcgg cggcaaggag aacggcgccg
    19381 cccaatgggg caccgtcatg gccgcgcagg gagtcggctc cctcctcggc ggattcgcgg
    19441 gcatgcgggt gcgcttccgc agaccgctgc tggcctccgt cttctgcacg ttcggtctgg
    19501 gagcgttcgc cggtctcctc gccgtgcgcg cgccggtgta cgtgctggtc ctgggctcgc
    19561 tgctgtccgg cgcgggattc gcgctgctgc acatcctctg gacgagcagc ttgcaggccg
    19621 atgtgccgcc ggacgcgatg tcccgcgtca gcgcgtacga cggtgtggcg accgtgctct
    19681 ccatgacggt gggctactgg tgggccgccc cgacggcgga ccgggtcggg gccacgtcgt
    19741 tgctgtggtt cggtgtggtg tggacgctgg tgagcgccgc cgcgatggtc acgctgccgc
    19801 agatccgccg gtccgcgccg ggcacggaca agcgcgaggc cgacgcggcc accccggagg
    19861 cccgagaacc ttccaccacc cactgagcgg cgcccgggcg gaccgtgtgc ccccgcccgg
    19921 gagccgtccg gcgccaagca gcgaaaggga agccgatgcc gcagtccgct ctttcggtcc
    19981 tcgccggaga catcaggccc gtgcccgcag acgtgtacgc catgttccgc gtgcaggccg
    20041 aacgccaccc cgggcggacg gcgctccggc agggagccga aggccgtacc tatcgcgaac
    20101 tgcatctctt cgctgaggaa ttggccggcc ggctgtaccg tcgcggcgtg cgcccgggca
    20161 cgtccgtcgc cgtacacatc gagcggggca tccacgcggt gggcgcactg ctggcggtgt
    20221 tacggctcgg ggccgcttat gtgccgctcg acgtgcacca tccgccggag cgttcccggg
    20281 gcgctctgcg tgagtccggc gcgacctgcg tactcgtctg cggggaagcg ccgttcgagg
    20341 acgtcgaagc cgtcgacctg ctccgaccca aaccgcgcga ggaggtcccc gccaccgcac
    20401 cgtcgccggc cctggacgat ccggcctaca tcctgttcac ctcaggatcg accggtgtgc
    20461 ccaaaggagc caggcttccc taccgcgccc tgtcgaacct ggtcacctgg ctgcgccgca
    20521 aggccagcgt gggcgtgggt gaccggacgc tccagttctc ccgggtgagc ttcgacgtgt
    20581 tcctcacgga ggtcctcggc accctggcca ccggcggtga gctgctggtg ctcgacgagt
    20641 cccgtcgcgc ggacctggac cacctcctgc ggttctgcga cgaccggcac atcaagcgcc
    20701 tccacctgcc gtacgcggcg ctccgcccct tcgccgagtg ggcccagtac cgccgggcct
    20761 cgctcccgca tctcgtcgag atctccacgg ccggtgaaca gccgcacgtg acggacgcgt
    20821 tggagcggct cctcggcgcc ggcgggcggc cgatccggct cacgaaccag tacggcccca
    20881 ccgagaccca tgtggtcacg gaggcgatcc tcaccggcga cccggccggc tggccccgca
    20941 cgccgtccgc cggtgtcgcc ctcgacaaca ccgtcgtcgc cctgctggac cccgcgggcg
    21001 ccgtcgtccc cctgggcgac gagggcgagg tgagcgtcgt cggcgcgcag gtgggactcg
    21061 gctacgtggg tccggtgtcc accgcgtcgg gtgcgggctt cgggcacgtc gaggcgctgg
    21121 gcggacgctg gggctaccgc accggagacc tgggccggat cgaggacggc gaactggtcc
    21181 tgcgcggtcg gatcgaccac caggtgaaga tcagcggcca ccgggtggag cccggcgaga
    21241 tcgagatcct cgccgaccgt gcggcgagcc tcgccgaagt ggccgccgtg cccgtggaca
    21301 cgcccggcgg tacgcgcacg atggcgctct tcgtggtacc ggcgccggga gccacggtgg
    21361 acccggacgc tctgcgcggc gcactcgccc gccgcctgcc ggaagcattg gtccccagcc
    21421 ggatcgtcct ctgcgaggcg ctgccccgca ccagctcggg caagatcgac cgcaggagcc
    21481 tcgccgagcg ccacgccgac cggaccgccc ggtcggcccc gagctccgca ctgcctgccg
    21541 aggagacgcg gatcgcgggt cgcctggccg cggtgctggg cctggatcgg gtcctggaga
    21601 cggattccct gctctccctg ggcggcagct cgctccaggc gatgaccctg ttgaccgagc
    21661 tggcggccga gttcggcagc acgccctcga tggaacggct gatgggcggc gcgagcgtct
    21721 ccgacctggc cgggcagctg agggcgggcg gttgggagga gcccgacagc cgcccgccgc
    21781 acgaagcgaa cgactccgtc ccgctcgtgc cctgcgaccc ggccgcggct gccggtcctc
    21841 ccggcaggac accgacatcg ctgctccccg cgtcgcccgt gcagtccgag atctggctgg
    21901 ccggccggct cggtgacccg acggcacaca acgtgacgct cgtcctcgac atcgcgggca
    21961 ggctggacga cgcacggctg aggcacgccc tccggcacac catcgcccgg catccggcac
    22021 tgcgttccct gctgaagcgt aagcgtgacc gcgtcttcgt gcaccgtcca caggactggg
    22081 tcaccccttt cgcgttcgaa gcggcagacg gggcggcgtc gcgcaccggc gcggaagcga
    22141 gcgaaagagc tttcgccgaa agaccgttcg acgtggggag cgacctgccg atccgcgtgg
    22201 ccctgctgcg cggccccggc cgggaccggc tgctggtggc gttccaccag cacgcggtgg
    22261 acgcccaggg catccaggcc ttcgtcgacg acctggccca ccggtacggc actcccgacg
    22321 acgcccgggc ggacgtgacg gacgaggccc tggacgcagc ggcacccggt ccgggcccgg
    22381 cggacgccgc caccctggcg cactggagat cggccctcgc gggcgtcacc ccggcccaca
    22441 cgacctggct gcggcgcgag ggcggctctc cctcgggccg atcggttcac cggcgcctgg
    22501 agcttccgta cgacgtgctg cacccgcacc ggggcgcatc cgggagcggt acggccaccc
    22561 ggttcgcgcg catcatcggt gccttcgcac atgccgcgca cgcggtcgga gcgccggatg
    22621 agttcctcac cggcgtcgtc acgacacgcc gcgtcccagg ggtctctccc gccgtgggct
    22681 gccacctggg cctcctgccg atcctgctgc ggccgggggc cgggctctcc gacacggtga
    22741 cctccgtaca cgcggccatg gcgacggcgc tgtcccaccg gcagatcagc ctgggtgagc
    22801 tgacgtcggt cctgccgaag ggcgcggccg tcacctcgac gttcgggctc gacgacgcgg
    22861 agaggcgcga agtcgacttc gcgggcaccc gggccaccac ccggtacgtc cacgcgcgca
    22921 ccctccagtt ccccctcgcc ttcacaccgt ggacgagccc tctggggacc gcgggcctcg
    22981 acgcggtgtt cgacgacggc ctccacctcc cggacaccgt cgacgcgctg ctcgacgaat
    23041 ggacacgcat cctgcgccac tccgcacagc gtccctgagc cgcgcatgcc ctgccggacc
    23101 cgggcccgcc gcaggccacc aggtcgcgtc gccgcgcgcc gtgacaccgg atcgcggcgc
    23161 tgtcagcatg atcggatgat cgacgccacg gacgagcagg acccctacat cgaacaccgc
    23221 aggctgctgt tcgccaccgc ctaccgcatg ctgggcagcg tcacggacgc cgaggacgtc
    23281 ctccaggaca cctggctgag gtggaggacc gtggaccggc acgacctccg ccaccccaag
    23341 gcctatctgg tccgcacggt caccaacctc tcgttggacc gcctcacctc cgcacgggcg
    23401 gtccgcgagg tctacgtcgg cccgtggctc ccggagcccc tgctgacctc tcccgacgtc
    23461 gccgcggaca ccgaactggc cgacagcgtc tccaccgcca tgatggtcgt cctggaaacc
    23521 ctcagtcccg tcgaacgcgc cgtcttcctg ctccgtgagg tcttcgccta ctcgcacgcc
    23581 gagatcgcgc agaccctcga acgccccgag ccgacggttc gtcagatcgc ccaccgcgca
    23641 cgcgatcacg tccaggcccg ccgcccccgc ttcgatgccg accgcaacca gcgccggaag
    23701 gtcaccaccc atttcatgga ggcctgcgcg ggcggcgacc tgaacgccgt catggaactg
    23761 ctcgcccctg atgtgaccgc ctggtccgac ggcggcggca aggtgaccgc ggcccgccgc
    23821 cccctccacg gcgccgatca cgtcgcgcgc tggatcacgg gcttcctggc caagcccggt
    23881 cttgccgacc tgaccatgga gccggtcgtc gtcaacggcg agctcggcat cctggccacc
    23941 ctcggcggac acccggtcgg cgccatcacg ttcgacatcg ccgacgaacg catccagaac
    24001 ctgcgcttcc aggtcaaccc cgagaagctg agcggcctga caccccgcaa cggctggacg
    24061 ctgccgtgag ttgacctctg aggccgcctc ttgcggcacg gccgctcctg ggcacagcga
    24121 cccaccagcc gagcacccgc gccagcgccg gcgcgcgccc gcgtccgtgc cagcccgcgc
    24181 ccgcgcccgc cgagggggag gctttgagtc gcgttccgcc tgccgcgagc atgctgtagt
    24241 cgccctgctg tgctgtccag gtgtcctatg cggtcttctg cccctttccc gcgctcgaag
    24301 gggaggggct gattcctgcc cgtatggcga ggcaaacagg gggaagcgca cggatctttg
    24361 tgcgattccg gtgtcagctt gtgtgcacct ggtggccgtt ggggtcgccg gggctgcttt
    24421 gcctatgggg gaattccatg tacctgcgtg ccttcggcat gccctttcgg cgtgcccgca
    24481 gaaggtcagc cgctctcgcc gcctcggcgg tcatggtctc cgcgacgctg gccctgtcgg
    24541 cgctgccgac cgccttcgcg gtcgccgacg acaccaagcc cggttccgtc tggggcccgg
    24601 gcggccccga cttcgaagtg ccggcggtga aagtcggctc gaaccggccc gtgaagaccg
    24661 aaccttcgcg gaatccgacc gacgaggcgt acgcgtcctg gctgcgggag cagcgcgagc
    24721 acgccgaggg cacaccgtcc gcgaaagccg ggccccgcag cggcgcggcc gacacctcgg
    24781 cgacctccct cgtgccggag gggcagggtg acgtgccctg gcaccggtac accagcttcg
    24841 ccgtcaccga cgccctgacg gcgaagatcg actactcgac cggcaatctg atgctgacgg
    24901 ccaccgactt cgacatcgcc ggtgtgggac agcgcctgac gctcgcgcgg acgtacaact
    24961 cgctggacgc accgtggggg aaggtctcgc agcgctggtg gcagcagtac gagcgctatc
    25021 tgcacctgtc ctccaccgag gcggtcctct acgacgcctc cggcgccacg gtccgcttca
    25081 ccaagcacag cgacggctcc ttcaccacgc cgaagggctg gtcggaggac ctgaagaaga
    25141 acgcggacgg cacctacacg ctgacgaagt ggaagtcggg ggcgtcggac acctatgacg
    25201 ccaacggcac gctgacgaag gccaccgacc gcaacaaggg cacgatcacg gtcacccagc
    25261 acgacgaggg cggcgagcac aagggcttca agctgaccga gacgcgctcg gggcgctgga
    25321 tcgacctgct gaggacggac gcctcgcagt ggcaggccaa ggacaacacc ggccgcaccg
    25381 ccgtgttcgg cctcgacggc gcgggcaacc tggccaccac cacggacacc gagggcaaga
    25441 cggtgacctt ccgtcatgac acctcgggcc gcatcgacaa gatcaccacc gcggagggga
    25501 gggtgacggt cttcacgtac gacgacgccg accgtgtcac ctccatgctg cgcggcaccg
    25561 gcttcgacag tgacggccac accggaccga cctggaccta cggctacacc ggtgactccg
    25621 cgaccgccgc cggcacgacc accgccaccg acccggagaa ccacgccacg aagtacgcgc
    25681 acgacggcga cggccaggtc accgaggtga ccgacgcgct cggccaccag cggtccacca
    25741 agttcgacgt caaccacaac atcgacaccg ccaccgacgc gatgggctcc ggtaccactc
    25801 cgggcaacgt caccgactac ggcttcgaca gccgcaacaa cctcaagacc gccaccctgc
    25861 ccaccggtgg ggccacggtg aacacctggc agaccatcgc cggcggcgac gtacccaagg
    25921 actccaccga ccccgacggt gagaagaccg ccttcaccta cgacacggcc ggcaacacca
    25981 agacggtcgc gcagaccggc accggcggcg gcagcgtctc ctacgaccac aaccccgcca
    26041 ccgcctcctg cggcggcttc gagggccagc gctgcgcgca gaagacgaag atgtcctcct
    26101 ccaagacggt gcagacggac ttccactacg acgccaaggg caacctggaa tgggccaagg
    26161 cgccggcgcc cctggggagg acgacgtaca cctacgacga cctgggccgc accaggaccg
    26221 tcaccgacgc ccgcggcgtc acggtcacct acacctacga caacctcgac cgcatccgca
    26281 ccgtcacctc gccgaacacg gtgaaggtcg agtactggta cgacggcgac ggcaacctca
    26341 ggcagcgttc cgacaacacc ggcaccgtct cctacgagtt cgacccgttg cagcgcgaga
    26401 cggtccgcca cctccaggac ggctcccaga ccctgctgtc ctacacagcg gccggcaacg
    26461 tggactccta ccaggacccc gccggcacgg tcacctacac gtggaacgag gtcgacaagc
    26521 tcaaggaact caaggactcc cagggccggg tcacgtcgta cacgtacgac aacaacgacg
    26581 tccgcaggac caccacgtac cccggcggca cggtccagac ggtcgaggtc gacaagtcca
    26641 gccggccgaa gtccctcaag gtcacctcgg atcagggcac cctggtgaac ctggcctaca
    26701 cctacggata cggcaccggc agcgccaccg acggcaacaa gatccgcacc agcaccgacg
    26761 gcgtcacggg attgaagcgg acgtacacct acgacggcgc gggccgcttc tcctatgcca
    26821 aggaggagaa ggcgggcgcg atcgccgact cctggcagta ctgctacgac ctggccggca
    26881 acctcacctc ccagggcacc gaccccggct gcccgcgcgg caccacctac acctacaacg
    26941 acgcccagca gctcacgaac aagtccacca cgacgggcac ttggtcctac gacgccgtcg
    27001 gcaacgaaac cgccggcgcc tccaccgacg actacctccg caccggcgag acctggtccg
    27061 accactcgca gatgacgtcg atcaccgtcg gcggcaagac gtacgcgggc cagtacggct
    27121 cgaccgatca gcgcgaacgc atcaggctcg gcgacacgtt cttccacaac ggaccgctgg
    27181 gcctgtcggc gaagacgaca gccggcacgg acatgggctt caaccgggaa cccgggggca
    27241 cgttgaactc catgacgacc gggggcaaga cgtacttcta cctcaccgac gccatcggca
    27301 gcgtgatcgg tctggcggac gaggacggca acaaggtcga cacctacgcc tacagccctc
    27361 gtggcgtgcg catcctggcg cagtcctccg aaccggtcgc ccagccctac cgcttcgccg
    27421 ggaactacca ggacccgacc ggcctctacc acctgaaggc ccgctactac gacgccaaca
    27481 caggccggtt cacccagccc gacccctcgg gccgggaaca gaacccgtac ctgtacgccg
    27541 aaggcgaccc cgtcaaccgc atcgaccccg acgggctgtt cagcctggga ggcatcgggg
    27601 acgggctcgg cgtcgcgacc atcctctacg aggggttcac cggcggaacg ggcgcggccg
    27661 agaaggcgac cgcggccatg atcgcggaca tcggtatcac ggggctctgc gaagccggag
    27721 ccgcggcgtt caccggaccg ggtgccgtcc ccgcgctccc cttctgcatg acgatcggcg
    27781 cggcggcggg cacgtacatc ggtgccacgt acaagagctg aggaacggac cgatcgtggt
    27841 tgccggagca ggcgtcgtcc tgctccggca accacggttc cgaacaggga gaacgagatg
    27901 atccaaccgg gaagagggcg ccagatcctc ctcttcggca tgctggcgct ggtctgcggt
    27961 gtccttctgc tggcgctctc ctcagggggc ccggccaccg cgttcggatg gctgctcgtc
    28021 gcgggtggag cgctgtgcgt gccggtgagt ctgctcagca ggaagaaggg gcaggggtga
    28081 tgtggtctct cgctgccccg cccccgttgc gggacggaca gtcggccctc tggttcaccg
    28141 tcggattcct cgtgctggtg ggcgtcgccc tgttcgtctt cagcaggagg aacaggtgac
    28201 gggtgacagg ccacaggtga agtaaccgcc gtgaagacgt gggaactctc ccgtcccgcc
    28261 cgggacacct ccgctcccgc gggggtgtcc cgggcggttc ctcacggagt ccagggaccg
    28321 agcatgtcct tcatcgcatc cgacatcgcg aactggagca gcggcccgta ggtgacccgg
    28381 ccgacaccga ggcgacggaa gcgctcgagg tcgtgcttga cgggatgggc cgtggagttc
    28441 accgggacgg cgacggcgcc ggtcaccgcc gtgagcagct cgtcgtcgtc ctggataccc
    28501 accgggtaga cgctgtcggc gccggcctgc tccagggctc gcagtcgctc gatcgcctcg
    28561 tcgaggacgc cggaagcact cggcgcgtgg atgaagaggt cggtgcgtcc gttcacccag
    28621 atcgggactc ccgcgtcgtc cgccgccgcg cgcaggccgc cgatgtagct cgcgtgctcc
    28681 tcggtactgc gcacgcggcc cccgtccgag tggacggtgt cctcgatgtt gagaccggcg
    28741 ccgccgacct cgatgagccc ggcgatgaga tccgcgggct tgtgcccgta tccggcctcc
    28801 aggtccacgg acaccgggac gtcgacggcc gcgatgatcg gcctgacggc ggcgagcacc
    28861 tcctcgaaag tctgcccctc gtggtcgtcg gctccccggg agtcggcgag cggatgactg
    28921 ccgatcgtca gcgcggggaa accgagagag gccgccgtcc gcgcggacca cacgtcccag
    28981 acggtcggca gtacgagcgg cttgtactcg gcgtgcagct gcctgaggcg ctgagcacgc
    29041 tcaacagtga tacgagagtc catgccaagg acgctacacc ggccccgcac acaatgccgc
    29101 gcaggcaggt gacggacgcc gagcgggtcc ggaccgcggt gggtgcccgg ccgacgtcgt
    29161 cgtaccgcac cgccgtgcct ggtccagggc cccgtccgcc aggagcgccc tctcaccccg
    29221 gcgcgacgaa ccccgattcg tacgccgtga tgaccgcctg ggtccggttg cgtgccccga
    29281 gcttcgccag gacggcgccg gcatgcgact tgaccgtctc cgtcccgacg acgagccggg
    29341 cggcgatctc cgcgttcgac atcccgcgtg ccatcaatcg cagcacctcg gactcccgct
    29401 cggtcaaccc ggccctcctc aaagtgtcct gggctgccgc attcccaccg cggtcgccgt
    29461 attcggcggc cagctgccgc accgacgccg ggaagagcag cgaatcgccc tcggcgacca
    29521 agcgcaccgc gtgcacgatc tcggcggccc gggcccgctt cagcaggaac ccgttcgcgc
    29581 ccgcgcgcag cgcctcgtag acgtactcgt cactctcgaa ggtcgtcacg acgaggatct
    29641 tcggcggctc ggcgaccgac cgcagcaccg cgcgggtggc ctcgatgccg tccatcagcg
    29701 gcatgcgtac gtccatcgcg accacgtccg gtcgcagctg ccgcaccagc gggatcaccg
    29761 ccgccccatc ggccgcttcc ccgacgaccc tgatgtcggg ctgcgcctcc agcaccgcgc
    29821 gcagccccat ccgcaccagg ggttcatcgt cgacgaggag tacggtgacc ggcatccggc
    29881 cagcgtagat cagcgcaggg gcagctccgc ccgcaccctc cagtcccctt cgtgaggccc
    29941 ggtggacgcc cgcccgccga gcagggcggc ccgctcccgt atgccccgca gcccgctgcc
    30001 ccgccccggg ccgggaatgc gggccgtcga cgggttgcgc acctccagat acagaagatc
    30061 gccggcaacc gcgacgcgga cccgcaccgg gaccggcccc gcatgccgca gcacattggt
    30121 cagcgcctcc tggaggatgc ggtagccctc ccgcgacacc ggccccggga cggtctccag
    30181 cggcccgctg acctcggcgt cgaccttcgc cccggacgcc cgcgccgact ccagcagccg
    30241 gtcggccccc gtcagggtcg gactctcgct caccggccgt ccggactccc gcagcacgcc
    30301 gagcacccgc tccagatccg cgagagccga ccggccgctc tcctcgatgg ccgccagggc
    30361 ccgatcggtg aacttcgcgt ctcccgccgc ccgcgccgct cccgcctgca ccaccgcgac
    30421 cgtcagcgca tgcccgatgg agtcgtgcaa ctcccgcgcg atgcggttgc gttcgagcaa
    30481 ctgctccgtc cgttcctcca gggcggcgag ccgctcgacg gccgacggac ccagcaaccc
    30541 gcgcgcgacg acggtcaccg accgacccag gcccaccacg gcgccgtaca gggcgagaag
    30601 gggaagcggg acgagcagtg ccgtccacca gcgcggagcc gccccgcgcg gcccgggcag
    30661 accgaccgga accggcccgc ccgcgccgac ggccaagtcg taggccaggg tgggcaacca
    30721 gacgcaggcg aacgccgctg ccgcgcccag gaccatccgc acctccagcc acagcaccgt
    30781 gcggagcctg ccccgccagg tcgccgacgg tgccacggag aagccggggt ccgagtcgcc
    30841 cgccacgagc agcagccggg cctggacccc ctcgcccgtc cgcaccgccg ggatcagccc
    30901 gaccggcacg aggaccagcg cggggaccca cggtctcgac gggtcgatga acatccagac
    30961 gctcacgacg agcatcggca cccacagatg cagcagtcgt gtgtacgtcg tcccccgcca
    31021 cagcgggcgc agcaggcggc ccatgccggc catcctcgca ggcggcacgc acaccgggcc
    31081 tcccccgagc gggggagacg gtccccaccg aagagggagg accgggccgc acgcggcggc
    31141 aagagtgagg gccatgacca gcatcgacgt acgagacctc accaaggaac acgggccccg
    31201 gcgggccgtg gaccgcctca cgttcagcgt gcggccgggt cgcgtcaccg gcttcctcgg
    31261 ccccaacggc gcgggcaagt ccaccacctt gcgcctcctc ctcggcctgg acagacccac
    31321 cgccggcacc gccaccatcg gaggccaggc ctacaccggc ctgcgccaac ccctgcgaca
    31381 cgtgggcgcg ctgctcgacg cgcaggccgc gcacggctcg cgcacgggac gcgatcatct
    31441 gcgggccctg gcggcgagca accgcatccc ggtccgccgg gtcgaggacg tgctcacgga
    31501 gaccggcctc gcaccggccg cgcggcgccg ggtacggacc tactccctgg gcatgcgcca
    31561 acgcctcggc atcgccgccg ccctgctcgg cgacccccaa gtggtgctcc tcgacgagcc
    31621 gtccaacggc ctggaccccg aaggcatcgt ctggatccgc gcgttgctca aacggctcgc
    31681 cgcggaggga cggaccgtac tggtctccag ccatctcatg aacgagaccg cctccttcgc
    31741 cgaccacctc gtcgtcctcg gccggggccg cctgctggcc gacaccccgc tgcgggactt
    31801 catcgacgcg cgtgtgcgac cgcacgtacg catccgtacc accgacccca ccgccctcaa
    31861 gagcgtgctc gaccgccacg gccacgacgc ggaggaacac gaggacgggc actggacggt
    31921 gcaccacgca cgcgtggacg acatcggccg cctcctgtcc gacgccggcg tccccctgct
    31981 cgaactgagt gcgcaggaag gcacgctgga acaggcctac ctcgacctga ccgccgccga
    32041 agcggagttc acggcccgca cccaggaggc ctgaccatgg gattcacgcc cgcactgcac
    32101 gccgagtgga tcaagatccg gacgctgcgc tcgctggtcg gcgccctgtg cgcgatgctg
    32161 tcggccaccg tcgtgttctc ggcgctctcc gcgttctcgg caggcaccga gaccgccacg
    32221 gacggcgatg acctcgaccc gctcttctcc gccctcttcg gcgtgaactt cggccagatc
    32281 gcggcgatgg ccttcgccac gacagccgtc tcgagcgagt tccggggcgg cgcactgcgc
    32341 ctgtcgctgg ccgccgtgcc gcaccggggc atctggttcg cggccaagct cacggcgatc
    32401 gccctgcccg tactgaccgt cggtctggcc accggactgg tcacggtcgc cgtgggcagc
    32461 gcggtgctgg gcgagaaggc ggacgccctg agcacggccg actgtctgcg cggcgcactg
    32521 ggctgcgccg cctacctgac cctgatggca ctgctcgcgg cgggcctgac ggccgtgctg
    32581 cggagcggga cagccgcatt gagcatcctc gttccgttcc tgctgatcgt gtccttcgtg
    32641 gtcggcgaca tgagcggcaa catggcggac ctgctccccg accgagccgg ccaagtagtg
    32701 ctccacagca cgtggcaggg gacgttgggc ccctgggcgg gtctcgccgt gaccgccgcg
    32761 tggacggcga cggccgtagc ggccgggacg tggcagctgc ggcacaggga tgcctgagcc
    32821 acccgccggc ccgctgccgt ccccgccggc ggacagggtc aggtcacgca ggtgcaccca
    32881 gcggcgggtg ttcgagcact cggggcttgt actcgaccag ctgaatgcgg ccgtcgaagg
    32941 tacggtggtc gatcatttcg agggcgacgt cgggatagcc gtcgtagatg cgttcctcgc
    33001 cggtggcccc ggtgatcacc gggaacatca ccacccggaa gcggtcgacg agtccggctt
    33061 cgagcaggga tttggagaga ctgaggctgc cgatggtgct gaggagcccc gagccgctcg
    33121 ccttgagggc gcggaccgcc ttgacggcgt cgtctcggac gagcgtagcg ttggcccacg
    33181 tcagcggctc ctcgagtgag gaggagaaca ccatcttggt cgcttgcgtg agctcgtcga
    33241 cggacgcctc ctcctcgggc cggaactccg cttgaccact cgggacctcg cctgcggcga
    33301 accccgacat cagacggtag gtgttcgttc ccatcaggta cgtggctttg ggctgtgtgc
    33361 cgagccatgc gaggtactcc gggccctcca ggccccagaa cccgggccac ccctctcccg
    33421 acgcacagcc gtccagggag gtgatgaagt cgacgagaag ctctgacatg gcggtattcc
    33481 ttcctgaggt gtcacgagct tggaccggac gggagccgaa aactcatcgg ccgcgctgaa
    33541 ggggacgctg cggggcaacg acgaaaccca gaaggcggca gctgtcctgt cccgctcagt
    33601 cgtggatgcc ggaagggctg tccccagggg acctcagtcg ctctgggcga ccggctcggg
    33661 ggcggagtcg agcgcgtcga gcactgcgtc gccgttcgcc ctcgcccact cggtcagcat
    33721 gtggatcgga tcgatcagcg tcgccccgag cggggtgagc tcgtactcga cgcggggcgg
    33781 cacctcggcg tacgcgtggc ggcggatgag tccatgcgcc tcgagccgtc gaagcgtctg
    33841 ggtgagcatc ttgcgggaga tgccgccgat caactcgatc agctggccat gccgcaccgg
    33901 gcccctgctg aggccgtaga gcacgaccac cgtccacttg tcggcgatca gctcgaccgc
    33961 aagacgcgcc ggacagtcgg cgagaaagga gtccccggga ccgaaaccgc tcatggcgcc
    34021 aaaggtacct gcgcggaagg tacctgccgg ttcctatcgg attcatagcc tgggccttct
    34081 ccccttccag aaccaggaga gtcatgcgag tcatcaccca gcagacgctc ggcggtcccg
    34141 aggtgctcac cgtcgtggac gcgcccgagc cccagccctt tccgaccgag gttctcgtcc
    34201 gcgtcaaggc catcggtctg aacccgctgg aggcgcgcct gcgggccggc gagttcccgc
    34261 tgatcggccg gccgccgttc attctgggct gggacatcag cggtgtggtc gaggaagcac
    34321 cggggacgtg gcggttcagg cccggcgacg aggtgttcgg gatgccgctg ttcccgcggg
    34381 cggcgagcgc ctacgccgag gtggtgtcgg cgccggcgtt gcacctggca cgcaagccgg
    34441 cgtcgctctc gcacgtcgag gcgtcggcgc tgccggtcgt cgggctgacg gcgtggcagg
    34501 gcctcgtcga cctcggcggc gtgaaggagg gcgaccgcgt cctggtccac ggcggtggcg
    34561 gcggggtcgg ccacgtggcg atccagatcg cgaaagcgct cggcgcgtac gtgatcacca
    34621 ccgcaggcgg aagcaagcgg acgttcgtcg aggagttcgg cgccgacgag gtggtcgact
    34681 acacggcggt cgacttcacc gacgcggtcc gcgacatcga tgtcgtgctc gacacgatcg
    34741 gcggcgacac cgtcgagcgg tcgctcgaag tgctgcgtcc gggcggtcac ctggtgacgg
    34801 cggtcgccga ggaggatgcg gagctcatcg ccaggtacga ggcggccggc atgcgcttca
    34861 gcggcatcgc ggtccaaccc gatccggacg ccctgcgagg tctcgtcgaa ctcgtcgaac
    34921 agggcaggct ccgggtccac gtgcaggaga cgttcccgtt cgagcgcgtc gccgaggcac
    34981 accggctgct cgacgccggt cacctccagg gcaagctcgt cctcaccgtc tgatcccgtc
    35041 gtggggcctc gcgcgagcga ggaccccacc gcggtgtcct acgggtcccc acgggccggc
    35101 tccggccttt cgtcccgacg caccgagtcg acctgtctcg tcccacgccg accgcgtcgt
    35161 tgtgcccgtc ggaggggacg aaaccgtcgt ccgaaccgtg cgctccagga tccaccggac
    35221 ggtcgtcggg ctcgccctcg ccctcggctc cgggccgcat caccctcgca agccttgccg
    35281 tagtcatgcc acggtcagga ttgcctttcc ggagacacgg cgttcacgca gggccctgga
    35341 ggcctcgttg aagcggtccc aggacccttg ccagccgatc tcgacggtga gggcaccctc
    35401 ggcggccagc tcggtgagaa ccgccaggtc cgcgccgacg tcgccttcga tgacgaagga
    35461 ggtcagcgac ttggccgggc cgacggtcgc gtacggcgga aagaccgcgg cctccccgga
    35521 ggtccagccg acgctctgca cgctgcctcc ggggctgagc aggttccaag ccgcgaccag
    35581 ctggggtccg ccgacgctgt cgatcaccac gtcgaccggt cgtcgcaggc cctccagtcc
    35641 gatcaggacg tcgtcggcgc cggcctcggc gagccccttc ccgcgcgctg ccgagccgac
    35701 ggacgcgatc acgtgggcac ccgcccgcgc cgccagttgg acggcgaacc ggccgacccc
    35761 gccggaggct ccggtgacca acaccgtctt gtcgggtccg agtccggcgg cccgcagtga
    35821 gcgcagcgcc gccactccgg cgaccggcag ggccaccgcc cgcgccaggt ccaacgcctt
    35881 cggcacctcg gcgagcgcac ccacgtcgat cgccacgcgc tcggcgaacg ctcctgaggt
    35941 cagggccacc acccgggtgc ctaccgccgg tccgcttcca tcggctgcgg cctggacgac
    36001 cactccggcg gagtccgaac cgagcaccgc gccctccggg acccgccctg aacgggcgtc
    36061 gttgaggtcg ccgtagttca acgaggcgtg ggagacggcc accaggacct gacccggacc
    36121 gggcgtgggg tcgcagaccg cggcgagacg gacggcggcg ggcgcggtcg gatcgacgac
    36181 gagagcacga acggacatgt gatccccctt ggttcacgac gtgtgacagc agtcatcatc
    36241 gacagccttg ccggtcgtcg gaaggaggca ctttcatgtc acgcggtcac atccgtgtta
    36301 ccgaagcgct gagggacgag gcctgcccgg tcaccgaggt gctcgaccgt gtggcgggca
    36361 agtggagcat cgggatcctg atcgcggccg cccacggccc ggtccgcttc accgaactcg
    36421 aacgctccat caacggcatc agccggcgga tgctcaccct gaccctgcgc aggctggagc
    36481 gggacggact gctcgtccgc accgtgtatc cgaccgtgcc gcccaaggtc gaatacaccg
    36541 tcacgcccat ggcccgtgaa ctccacgact cactgaccgg actggtgggc tgggccgagc
    36601 gtcaccggtc cgccatcgcg gaggctcgcg ccgcctacga caccgcgacc gagcagcgcc
    36661 ccgacatcga ctgactgaac gtccccgggc gaaccccact cctgcgaaat cgcaagagcc
    36721 gaccggggga gcgggcgatg agcccgtcat cagcaaggca atactcgcga gatcgaccgg
    36781 acacgccgga gggtcaccgg tcctcggcac tgaccgggca cgtcaggatg accgtgccgt
    36841 cactcgcccc cgtcgtcgat tcggcgagga gccacgccga ggaccaggtt ctccatggcg
    36901 tgaggcatcg gtccgaagcc ggcaacccac gtttcgacga gatggacgac gccggcttcg
    36961 tcgatgccca ggaagaaccg accgtggtcc agctcgccga gcgggtagag acggcgcccg
    37021 atcgcctcgc cccactgcgc gaatcggtcc tcctcacccc aggccagctc agggtcaagc
    37081 tcgaacggcg tgcgcgcaca gctgatccct ggtccgctga cgttcaccgt cagaccgccg
    37141 aactcttgca ggaaggcttg cgcagcgtcg tgcatggaca ggccgaccga ttcgaacagg
    37201 gatcgccagc gggacgtgtc caccctccgc ccaggcgtcc accccgaggc cttcagcacc
    37261 gcctcgaccc tcggcgacca actactcatc cggaacccgt cctcctcggc tggggggagc
    37321 agcgatcatc ccagtagccg acgcaacagg gcagtgagtg aacgcctgac gggggcgagc
    37381 cagagcccga tctcgaccaa caccgtcgaa cgagccatca atcgattgaa gaactcccgg
    37441 gccgtggcaa cgcggtacga caagcacggc tatgtcttcc tcgaaacggt caccgctgcg
    37501 ggcctggtca tctggctgcg gtcatgattc gccgtgcggg tcatccgtct cggacgcaag
    37561 cgactcggcg ccgagcggcc agcggtagcc ggcgtcatgc agcttgctca acgccgagag
    37621 atcattggac accagcacct gagccaaccg ggccgctgcg gcgacgacag cggaccagcc
    37681 cggtgagacc agacaagcct cgtcgcgcgc agcggcgccg accgacttct gcaccgcgct
    37741 gtaggcggta ccaacccctg ccatcagctc aacttcctcc tcgctgcgta ggcactgccc
    37801 cagccagggc gacgggttgt ccgcatcgca gaagtcgtcg aagagcacat gcacgatgta
    37861 gttgaggtcc tcgaactgat ccggatcgag ccacacctct cgctgccatg tcgggctggc
    37921 cagggccacg acggcaggaa caacatggag gcgatagtgg ggcagagcaa taccgtgatc
    37981 aatcacgagc caagagtaag cgtcacatga tcggccggag agctcctagg cctatgtgat
    38041 ctcgtggtca gtcggtaggc ggcggaattg aggatggcat cctcagaacg tacctaaacg
    38101 cggcctgtgt tgggccgtgg cgctggaagg cagaagaact gtggcgatct gtttcgagct
    38161 ggtagtgaac ttcggggacg acgccgaggc ggcacaggta gcagcccagg tcgagacgaa
    38221 gcaacgtgtg cttcgcgcgg acgcccaccg tattcctctc caccggccgc tgatggcgaa
    38281 ggtgggctca tgcttcgagc tgtcgatcct tcaggcggcg gtgagttggc gtagtgcctt
    38341 ggacggcggc ctctcacggt tgccgctcag cgcagcggag ttgaccgaac tggggcatca
    38401 actctacgac ctgcttgcgc agttgcgcgg attcgttgcc gcgaaggtcg gctgggatcc
    38461 ggaatccttc cttgaccccg gtgagctcag gcgcgagtgg tcagatgaat tgaacgacgg
    38521 cagcatccac gggctcgtgc tctgtgaaga gctctatgcg gaacttgacc tgagagctga
    38581 ctacgaggtg ttccagcccg gctatcgatg gatgccgtat cgcggagagg aaccaagtgg
    38641 cctcatcgcc gactgacgaa gaggtgggcg aggcgtcaag atgtcgctgg gcccggcgct
    38701 ctgcccgccg cgcgggaacg ggcgccgcgc gctctggccg gccggtcaca ccaggaccgg
    38761 tagtgcggcc ggtccgcgta ggagacgggt gcggcgccac gccagttggt ccggggtcac
    38821 ggcgagccgg atcgtgggga accgggtgag gaccgctcgc agggcgatct ccgtctctgc
    38881 cctggccagg ggcgcgccga cacagcggtg gatgccgtga ccgaaggcga gatgagcgga
    38941 ggcgtcccgg tccaggtcga gccggtccgg ctccgggaac cgcctcggat cgcgatcggc
    39001 ggcacccagc gcgaccagca ccgggacacc ggccgggatg tcgatgccac cgagaccgag
    39061 ggcctccgtg gtgaaacgga acgtggcggt gctgacaggg gagtcgaacc ggagcagttc
    39121 gtccagcgcg cccggcacct cgcgcggatc gctgcgcagc ccgtcgagtt cggcggggtg
    39181 tcgcaacagc gccagcacgg cgttcgcgag gaagtcggtg gtggtctcgt gtcccgcgac
    39241 gagcaacagc gcggccaggg agaccagttc gtcctcgctc agccgatcct ccgcgtcgcg
    39301 ggcgcggatg agccggtcca gtagacagtc accgggctcc cggcgcttgg cggcgatgag
    39361 gtccgtcatg tagccggcta cggcatgcga ggccgcgtcg atgacctcgg gctctccggc
    39421 cgtgaacaac tgcgcggacc aacgccggac gtcggcccgg tcctcctccg gtacgccgag
    39481 gagttcgcag atcacgagga ccggcagggg cgccgccagg ccgtccacca ggtcgaaggg
    39541 ttcgcccacg ggccatcggt ccagcagttc gtcggtgacg cgggcgatga acgggcgcag
    39601 ccgtgtgacg gcacccgtcg tgaacgcctt ggtcaccagc gcgcgcaggc gagtgtgccg
    39661 gggcgggtcg ctggccagca tggtgtgcgc caccgcaggg tgcaggcgtc gccgggacgt
    39721 cttgcccgcg aagaacgcgg ccgtgtcctt cgacagccgc gcgtcgccga gcgcctccct
    39781 ggcctccgtg tagccggtga ccaggtagcc gatgtgtccg tccggcccgg gcacgggctg
    39841 caccgggcag gtggaacgta tggccgcgta ggcgggatag ggatcctgga ggaagcgggg
    39901 atctttcatc ggatcggtca tgccgtcagc ctccgaccgg ccgcggccgg acgtcacctg
    39961 cgacacgcac gaggagcgct cgtggacccc gtgacaccat gcgggcatgc gatccgacgt
    40021 cacgctgcac cccctcgacc gcgcccgcct ccaggatctg ctgcacgccg ccgtcgagga
    40081 cgccgatccg ctcgaggtga tgccgcccgt gccggggccg ggcggatgga cgaccgagcg
    40141 ccggtcggcg ttcgtgcgct tccacgagtc gcggtcgctg tcggcgcatc cggtggagac
    40201 caccttcgtc atcgccgtgt ccgggcgcgt cgtgggagcg gcacggctgt gcccggtgga
    40261 ggaccgggac gggacggtcg aggccggggt gtggatcgga cggtcccacc ggggcaccgg
    40321 cgtgggctcc gccgtgctgg agcttctgct ggaccgggcc cgcgcgagcg ggtgcgatga
    40381 ggtctatgtg agcacgacgc cgcagaacag cgcggtgcgg gctctcatgg ccggcatcgg
    40441 gacggagctc gttgccgacg gcgacgaact cgtggggcgc gtgcgtctga cgagctgacg
    40501 gcccgtggcg cgtacgcgct cacctgggct ggcgctcgca tgcttgcctc tcggctgtgc
    40561 cgaccggcgt aaggcccccc cccgcgagac ggagcccccg ccccgcggca gtgcggcccc
    40621 atccggaggc gcggactcag ccgcgctccg cgcgcagacg caggcgcccg tcatggatct
    40681 cggcgacacg gtcggcggcg gtgaggtggg tgtggtcgtg ggtgaccacg acggtcgcgg
    40741 tgccgcgccg ccgggtgagc cgggcgatca ggtcgatcac actgctcccg cgctcgtggt
    40801 cgagggcgct ggtgggctcg tccacgagga ggagggtggg ctcgttcatc agggcgcggg
    40861 cgatgttgac gcgctgacgc tggccgccgg agagctcgtg gggccgccgg tcggcccggt
    40921 ccgcgaggcc gaccgcgtcg agcagttccc tcgcccggtc ccgcgcggcg cgggcgctgc
    40981 gaccgtcgat ccgggccatg acctggagtt gctcggccgc cgtcagggac ggcagcaggt
    41041 tgggctgctg gaagacgatg ccgatcccgc ggcggcgcag agcggtcagt tcgccgcggg
    41101 acaggccggt gacgcgggcc ccgtcgaggg tgacggtccc ggagtccgga cggatcaggg
    41161 tggcggcgac ggccagcagg ctggacttgc ccgaaccgga cggtccgacc acggccgtca
    41221 cgctgcccct gggcacctcc aggctgaccc cgctgagggc ggtgaggcgt gagtcaccgt
    41281 cggggtaggt gagggtgacg tcggtcagga tcaagctcat cgtgcgctcc ccagagcggt
    41341 cagcgggtcg acggaggtga tgcggcggat ggacagggcg gctcccgaca gaccgaggac
    41401 gatcatcacc gccgccggga tcaggacggt ggcgggcgtg aggaggaacg gcacgtccga
    41461 cccggccacc agagccccca cggcggcggc gatgccggtg ccgagcagcg tgccgcccgc
    41521 gagcaggacg accgcctggc ccagtgcgtc cttgaggaga gccgcggtgg aggcgcccag
    41581 ggccttgagg acggcgacgt cgccgccgcg ctggacggtc cacacggtga agaaggcccc
    41641 gacgacgagg gcggagatgg cgaagagaag agcgcgcatc agttgcaggg agccgttctc
    41701 ggaggtgtag gaaccgatgg cggacagcga gtcgccggtg gacaccgtcc tggtgccggt
    41761 ccgctcgtcg gtggtccgga tgtcggcggc cgaggtggtg gccagggcga tgacggtggc
    41821 cgtggggccc ttctcgccgt cggagggcgg cgcgatcctc cgccagacgt ccaggtccgc
    41881 ccagaccacg ggggtgtggc tgaaggaggc gtcgcccgag acggcagcca cgtgaagccg
    41941 tcggcctgcc accgtgagga gatcgccgac gtgcacggcg aggtcgtcgg cggccgcggc
    42001 ggacaggacc accgcaccgc cgccgatccg gtcgccgtcc ggtgcgaggc gggagcccgg
    42061 ccggacgccg aacacggaca gagcggcgct ccgctccccg gcggcgccct tggccgtggc
    42121 gatccccagc ggctcggcgc tctcgacacc cggcgcctcg gaccactgct cccactgcgc
    42181 ctcggtgacg gtggagtccg cgtacgacag gtcccggccg ccgtcgggag cctggaacgc
    42241 gatcctgtcg gcgggcagcc ccgtgatcgc cgagacgttc tcccggccca gcccggccgt
    42301 cagtccggac agcagcccga ccagcagggt gatcaatacg atgacgctcc ccatcagggc
    42361 gaaacgcccc ttggcgaacc tcaggtctct ccacgcgacg aacacggtct cggtacgtcc
    42421 tctccggcga cggcagcggc agacctccac cctcgtgccg ggccccgggg cggcgcgtcc
    42481 ggcgcaggac cgcacttcag gggccgaagg acggcgccgg ggttccatct ttcgatggag
    42541 gccgcgagcc ggcgggctcc gtaacctggg agacactgtg aacaccgtcg cccccgcccc
    42601 gaccccgacc acccgggccc tgacctggtg cctgcacctg ctggtcatcg gcctgctcac
    42661 cctggccgcc ggccgggccg tggccggcga tccgccccac cccggaggga ccgtcgccgc
    42721 cgcagcgctg tgcgcttcgg tgtacgcgac cggccccctc gtacgacgtc atcggcgccc
    42781 gcggcgcgcc gccgcgctgt ggctggccgc cgtgggcgtg atgtggctgg tgctgctcgc
    42841 cctgtcgccc gaggcggtgt gggtggcctt cccgctgtac ttcctccagc tgcacctgct
    42901 gccccgccgc gccgccctgg tggcggtggg cgccacggcg gcagcggccg ccgcgggctt
    42961 cgccgcccac caggatgcct tcagccccgc catggccatc ggtcccggtc tcggcgcggc
    43021 cgtggcgatc gccgtggtcc tggggtacca ggccctgtac cgggagagcg aacagcgc
//
