LOCUS       NZ_BMSI01000003        21053 bp    DNA     linear   CON 02-AUG-2024
DEFINITION  Streptomyces asoensis strain JCM 4185 sequence03, whole genome
            shotgun sequence.
ACCESSION   NZ_BMSI01000003
VERSION     NZ_BMSI01000003.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces asoensis
  ORGANISM  Streptomyces asoensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 628564)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014649075.1-RS_2024_08_02
            Annotation Date                   :: 08/02/2024 04:45:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,813
            CDSs (total)                      :: 7,736
            Genes (coding)                    :: 7,563
            CDSs (with protein)               :: 7,563
            Genes (RNA)                       :: 77
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 53 of 173
            Pseudo Genes (incomplete)         :: 140 of 173
            Pseudo Genes (internal stop)      :: 10 of 173
            Pseudo Genes (multiple problems)  :: 28 of 173
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:21:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 239516
            Orig. end                         :: 260569
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMSI01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21053
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21053
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21053
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11053](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11053)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(205..214)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    complement(423..436)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.7"
                     /tool="antismash"
     misc_feature    435..450
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: strong, score: 24.29"
                     /tool="antismash"
     misc_feature    complement(605..620)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 22.38"
                     /tool="antismash"
     gene            749..1513
                     /locus_tag="IE189_RS09970"
                     /old_locus_tag="GCM10010496_20250"
     CDS             749..1513
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973740.1"
                     /locus_tag="IE189_RS09970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20250"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_189919895.1"
                     /transl_table=11
                     /translation="MSTDVSSAENEGGATVRTARVPKYYRLKKHLLDITETQSPGTPVP
                     PERTLAAEFDTSRTTVRQALQELVVEGRLERIQGKGTFVAKPKVSQALQLTSYTEDMRA
                     QGLEPTSQLLDIGYITADDRLAALLDITAGGRVLRIERLRMANGEPMAIETTHLSAKRF
                     PALRRSLAKYTSLYTALAEVYDVRLAEAEETIETSLATPREAGQLGTDVGLPMLMLSRH
                     SLDQEGRPVEWVRSVYRGDRYKFVARLKRPAE"
     gene            1613..1903
                     /locus_tag="IE189_RS09975"
                     /old_locus_tag="GCM10010496_20270"
     CDS             1613..1903
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020130766.1"
                     /locus_tag="IE189_RS09975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20270"
                     /product="DUF3311 domain-containing protein"
                     /protein_id="WP_189919897.1"
                     /transl_table=11
                     /translation="MSESPEVTRGPVVTPVRVAIALCLLAPFVAMLWVGSYAKVDPTFI
                     GIPFFYWYQMLWVPLSAVLTVTAYKLWRRDQRARATAPAASGSAPKGGASR"
     gene            1900..3528
                     /gene="mctP"
                     /locus_tag="IE189_RS09980"
                     /old_locus_tag="GCM10010496_20280"
     CDS             1900..3528
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006848 - pyruvate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="mctP"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674905.1"
                     /locus_tag="IE189_RS09980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20280"
                     /product="monocarboxylate uptake permease MctP"
                     /protein_id="WP_189919899.1"
                     /transl_table=11
                     /translation="MKDGVNGVALGVFIFFFLAVTVMGFLAARWRKAENEHSLDEWGLG
                     GRSFGTWVTWFLLGGDLYTAYTFVAVPAAIYAAGAAGFFAVPYTILVYPLIFTFLPRLW
                     SVSHKHGYVTTSDFVRGRFGSKGLSLAVAVTGILATMPYIALQLVGIQAVLDVMGVGGG
                     ENTNWFVKDLPLLIAFGVLAAYTYSSGLRAPALIAFVKDTLIYIVIAVAIIYIPIKLGG
                     FDDIFAKAGEAFSQTNPATGKPRGALAPAEPGQWTYATLALGSALALFMYPHSITATLS
                     SRSREVIRRNTTILPLYSLMLGLLALLGFMAIAAGVKVTNGQLAIPQLFEDMFPSWFAG
                     VAFAAIGIGALVPAAIMSIAAANLFTRNIYKDFIKPDATPKEETRVSKIVSLLVKVGAL
                     VFVLTMDKTVAINFQLLGGIWILQTFPALVGGLFTRWFHRWALLAGWAVGMVYGTFAAY
                     GVASPTQKHFGGSSKEIPGIGEIGYIGLTAFVINVVVTVVLTFVLRAAKAPDGVDETKP
                     EDYTADAGDPGVQVELPPATAGTSH"
     misc_feature    3697..3711
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: strong, score: 25.12"
                     /tool="antismash"
     misc_feature    3728..3742
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 24.21"
                     /tool="antismash"
     misc_feature    3736..3749
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.46"
                     /tool="antismash"
     regulatory      3764..3853
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            3998..6385
                     /locus_tag="IE189_RS09985"
                     /old_locus_tag="GCM10010496_20290"
     CDS             3998..6385
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020130769.1"
                     /locus_tag="IE189_RS09985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20290"
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="WP_189919902.1"
                     /transl_table=11
                     /translation="MTIAPAGPVPATEPESDGPGTALLRTLTELTADLPDADPGRVAAA
                     ALRGRSGRADEAELRELATEAAAGLISEDPAYSKLAARLLTVGIAAEAASQGVTSFTGS
                     VAVGHREGLVADRTAEFVRVHAARLDALIDERADDRFGYFGLRTLHSRYLLRHPITRKV
                     VETPQHFLLRVACGLADEGPSSGEDTPRALDEVAALYGLMSRLDYLPSSPTLFNSGTRH
                     PQMSSCYLLDSPLDELDSIYDRYHQVARLSKHAGGIGLSYSRIRSRGSLIRGTNGHSNG
                     IVPFLKTLDASVAAVNQGGRRKGAAAVYLETWHSDIEEFLELRDNTGEDARRTHNLNLA
                     HWIPDEFMRRVNADEPWSLFSPADVPELVDLWGEEFDAAYRSAEAKGLAKKTIPARDLY
                     GRMMRTLAQTGNGWMTFKDAANRTANQTAEPGHVVHSSNLCTEILEVTDDGETAVCNLG
                     SVNLGAFVDTAAGTLDWERLDDTVRTAVTFLDRVVDINFYPTEQAGRSNARWRPVGLGA
                     MGLQDVFFKLRLPFDSPEAKALSTRIAERIMLAAYEASAGLAERNGPLPAWEKTRTARG
                     VLHPDHYGVEFTWPERWAALRERIARTGMRNSLLLAIAPTATIASIAGVYECIEPQVSN
                     LFKRETLSGEFLQVNSYLVQDLKELGVWDARTREALRDSSGSVQDFAWIPADVRALYRT
                     AWEIPQRGLIDMAAARTPYLDQAQSLNLFLETPTIGKLSSMYAYAWKSGLKTTYYLRSR
                     PATRIARAAQAQAPAAVPLQQVTEPDAVACSLENPESCEACQ"
     gene            6385..7410
                     /locus_tag="IE189_RS09990"
                     /old_locus_tag="GCM10010496_20300"
     CDS             6385..7410
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020130770.1"
                     /locus_tag="IE189_RS09990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20300"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_189919904.1"
                     /transl_table=11
                     /translation="MTSAPEKTEKNLLDPGFELTLRPMRYPDFYERYRDAIKNTWTVEE
                     VDLHSDVSDLAKLSEGEQHMIGRLVAFFATGDSIVANNLVLTLYKHINSPEARLYLSRQ
                     LFEEAVHVQFYLTLLDTYLPDPADRAAAFAAVENIPSIREKAEFCFKWIDEVEKLDRLE
                     SKADRRRFLLNLICFAACIEGLFFYGAFAYVYWFRSRGLLHGLATGTNWVFRDETMHMS
                     FAFEVVDTVRKEEPDLFDDRLQEEVTAMLREAVDAELQFGRDLCGEGLPGMNTDSMRQY
                     LECVADQRLTRLGFAPVYGSENPFSFMELQGVQELTNFFERRPSAYQVAVEGTVDLDED
                     F"
     gene            complement(7323..7565)
                     /locus_tag="IE189_RS09995"
                     /old_locus_tag="GCM10010496_20310"
     CDS             complement(7323..7565)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010047586.1"
                     /locus_tag="IE189_RS09995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20310"
                     /product="hypothetical protein"
                     /protein_id="WP_189919907.1"
                     /transl_table=11
                     /translation="MNTNQIEGLIGMLLTFGILVLLVLPSAFGVARDRRADRQIREAQE
                     ARGEQEDQKSSSRSTVPSTATWYAEGRRSKKLVSS"
     gene            7659..8624
                     /locus_tag="IE189_RS10000"
                     /old_locus_tag="GCM10010496_20320"
     CDS             7659..8624
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030121.1"
                     /locus_tag="IE189_RS10000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20320"
                     /product="GlxA family transcriptional regulator"
                     /protein_id="WP_189919909.1"
                     /transl_table=11
                     /translation="MLKNVAAILLDGVHPFELGVVCEVFGIDRSDEGLPVYDFAVASAE
                     GPTLATRAGFTLSTPHGLERLENADLIAVPAGDTYGRRDFPPELLDALRRAVDRGTRVL
                     SVCSGVFVLAAAGLLDGRRCAVHWRHAEQLARQYPRTTVEPDVLYVDEDPVITSAGTAA
                     GIDACLHLVRKEQGPEVANRIARRMVVPPHRDGGQAQYIERPLPRSRCDTVGEVLAWME
                     QHLDQEITVERLAERAHMSPRTFARRFQQETGTTPYRWLLRQRVLLAQHLLEATDETVD
                     AIAWRAGFGTAGALRHQFVQALGTTPNAYRRTFRGPQAAA"
     misc_feature    7660..7676
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.34"
                     /tool="antismash"
     gene            complement(8634..10004)
                     /locus_tag="IE189_RS10005"
                     /old_locus_tag="GCM10010496_20330"
     CDS             complement(8634..10004)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020130772.1"
                     /locus_tag="IE189_RS10005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20330"
                     /product="cytochrome P450"
                     /protein_id="WP_189919911.1"
                     /sec_met_domain="p450 (E-value: 2.2e-67, bitscore: 222.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVESMKPTTPKTPGPSEPPLAGGGLPLLGHGWKLVRDPLAFLAR
                     LREHGDVVRLRLGPKTVYAVTSPELTGALALSPDYIISGPLWESLESLLGKEGVATANG
                     PLHRRQRRTIQPAFRLDAIPGYGPIMEEEAHALVDRFRGAEVVDVTAEAFRVSVRISAR
                     CLMRGSYMDARSERITSALATLFAGMYQRMVVPLGPLYRVPIPANREFNRALADLHRLV
                     DEIVADRRASGQKPDDLLTALLEAVDENGDPIGEQEIHDQVIAILTPGSETAGSVVMSL
                     LNVLTEHPDQVDKIREEVKNVVGDRPVAFDDVRKLQHTANVVVETMRLYPAVWILTRRA
                     VTETELGGYRIPAGADIVYSPYAVQRDPRSYERHTEFAPDRWLPGGSARVPKYAMAPFG
                     VGNRKCPSDHFSMAELTLITAVLASAFRFEPAPGSDNRTHIGITLRPRRLRLRAIPG"
     gene            complement(10001..11053)
                     /gene="cyc1"
                     /locus_tag="IE189_RS10010"
                     /old_locus_tag="GCM10010496_20340"
     CDS             complement(10001..11053)
                     /EC_number="4.2.3.37"
                     /GO_function="GO:0052680 - epi-isozizaene synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cyc1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992851.1"
                     /locus_tag="IE189_RS10010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20340"
                     /product="epi-isozizaene synthase"
                     /protein_id="WP_229901172.1"
                     /sec_met_domain="T1TS (E-value: 5.3e-62, bitscore: 205.7,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAPAVPPSLSLPVIEAAFSRRLHPYWPQLQERTRSWLLEKRLMP
                     ADKVAEYADGLCYTDLMAGFYLGAPDEVMQAIADYSAWFFVWDDRHDRDVVHGRSSSWR
                     RLRFRLHAALDFPAEHLHHSDPLVAGLADSVGRLYSFLPGTWNARFARHFHAVIDAYDR
                     EFHNRTEGRVPGVEEYLALRRLTFAHWIWTDLLELSAGTELPDRARKHPAYRRAALLCQ
                     EFAAWYNDLCSLPKEIAGDEVHNLGISLITHEGLTLEEAVEELRRRVGECISGFLAAEK
                     DVLLLADRLADGTVRGNETSAAVRACVGNMRNWFSSVYWFHHESGRYMVDSWDDRSTPP
                     YVNNEAAGEK"
     misc_feature    11306..11321
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.96"
                     /tool="antismash"
     gene            complement(11382..12032)
                     /gene="def"
                     /locus_tag="IE189_RS10015"
                     /old_locus_tag="GCM10010496_20360"
     CDS             complement(11382..12032)
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983603.1"
                     /locus_tag="IE189_RS10015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20360"
                     /product="peptide deformylase"
                     /protein_id="WP_189919914.1"
                     /transl_table=11
                     /translation="MAQQDTDQQHAGVLPVDDEGFVIDTGEAEARELTWREAGTSRPIT
                     VVGNPVLHKECRDVTEFDDELRQLVADMFASQHTAEGVGLAANQIGVDLKVFVYDCPDD
                     DGVRHTGVVCNPRLVELPAERRRLDDSNEGCLSVPTAYAPLARPDYAEVTGQDERGNPI
                     KVRGTGYFARCLQHETDHLYGYLYIDRLSKRERKDALRQMAENEPRYPVVAND"
     misc_feature    12069..12087
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.61"
                     /tool="antismash"
     gene            complement(12156..13136)
                     /locus_tag="IE189_RS10020"
                     /old_locus_tag="GCM10010496_20370"
     CDS             complement(12156..13136)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889310.1"
                     /locus_tag="IE189_RS10020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20370"
                     /product="hypothetical protein"
                     /protein_id="WP_189919916.1"
                     /transl_table=11
                     /translation="MRIFGKGRHRPSASWRQATDRAFTLIGDGRYEDAGALLTRAADLE
                     PWLSESWFNLALLHKFRHDWEQARTAGLRAVALLDREAGAPDWWNVGIAATALQDWPLA
                     RRAWQAYGLRVPGEATGAGEPVGMELGSAAVRLSPEGEAEVVWGRRLDPARMEVLSIPL
                     PSSGRRWGEVVLHDGVPHGERTTATGHSYPVFDEIELWAPSPVPTWVVLLEAATESDRD
                     ALEQLAADAGFAAEDWSSSVRLLCRMCSESRMPSDEGDGEHLDPHDHSEPGHPGPLGHR
                     TDGQLWVPERECGVAAPASLVRGLLDGWVADSPDSRDWRDLEEVC"
     gene            complement(13262..14563)
                     /locus_tag="IE189_RS10025"
                     /old_locus_tag="GCM10010496_20380"
     CDS             complement(13262..14563)
                     /EC_number="3.1.4.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016644068.1"
                     /locus_tag="IE189_RS10025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20380"
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_189919918.1"
                     /transl_table=11
                     /translation="MTARRSPLALHAVAALLVAGSLLVTFATGVEERPVALAFGVLVAV
                     GELARPPGGPPLREAAPLGAAGSLAYALVGAHAGHPTHHGVAQVVTVVAAASLLGGVPQ
                     LARGEGPVLDHLVRRVLAVGFAAVCFQPLHNRGVFDGWSGPAHTLLLLALLVLTVLCDT
                     VVVAVLARSRTGWPFAPTLRDELRGLPGIGSAVCATGAVMALAVAVVGLWALPVFSVPL
                     LLTQLSLRRHAAVRATYRQTIASLARATEIAGYTPAGHARRVAALSHAVGRDLGLPEPE
                     LTVLEYAALMHDIGQLSLVDPVPDGATAGLPVAQQRRIALLGGAVVRQTGADARVAAVV
                     ERQADPYPEQPPAARIVRVVNAYEEKARGRGPGGPLAALEELRLGTGREYAPEVVEALA
                     AVLRRTGAQAGVHPPASGPGGASGRVVAGDSWAV"
     gene            complement(14560..15867)
                     /locus_tag="IE189_RS10030"
                     /old_locus_tag="GCM10010496_20390"
     CDS             complement(14560..15867)
                     /EC_number="3.1.4.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674892.1"
                     /locus_tag="IE189_RS10030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20390"
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_189919920.1"
                     /transl_table=11
                     /translation="MEGIPARARGYAACAALGSLLCTLPPGPRTPWWAVALLAGLYAGG
                     ERIARRRFAGTLHPVLLAGAFLLEPAAAALVPLPGALFSHVERRPFALRRLWRAAQASL
                     AVWAASHVHGALGGREAVAACELPRALVPAGAAVLVFCAALALLNGGMRALAEGLPLRR
                     VCRGLFLRSLAPLAVHGLAGLMTAVLWSSPYGPLAALLVLFPTAVSWWVFAQYHRERAA
                     HQATIRALVQAVDIKDGYTRGHSERVGQASVLIARELGMDESRIEMLRFAGILHDVGKL
                     GVPTRLLRKDGPLTPQERRVIELHPEYGHEITRGIAFLGEARSAILHHHERLDGTGYPY
                     GLSGGQIPEPARVVAVADAFDAMTSTRSYSRARPVGAALEELRRCAGAQFDPRMVAALA
                     DVVERDGWHPVVTADETRPAAPPPARTPDDRSGARR"
     gene            complement(15985..16287)
                     /gene="rsrA"
                     /locus_tag="IE189_RS10035"
                     /old_locus_tag="GCM10010496_20400"
     CDS             complement(15985..16287)
                     /GO_function="GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136687.1"
                     /locus_tag="IE189_RS10035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20400"
                     /product="mycothiol system anti-sigma-R factor"
                     /protein_id="WP_189919922.1"
                     /transl_table=11
                     /translation="MSCGDPHETDCGEVLDHLYEYLDSEMPPLDRDKFQHHFEECSPCL
                     EKYGLEEAVKKLVKRCCGSDDVPTDLRAKVMGRIDLIRSGQTVPEHDVTATTQES"
     gene            complement(16284..16979)
                     /gene="sigR"
                     /locus_tag="IE189_RS10040"
                     /old_locus_tag="GCM10010496_20410"
     CDS             complement(16284..16979)
                     /codon_start=1
                     /gene="sigR"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973756.1"
                     /locus_tag="IE189_RS10040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20410"
                     /product="RNA polymerase sigma factor SigR"
                     /protein_id="WP_189919924.1"
                     /transl_table=11
                     /translation="MGPVTGTDAGTDNGQAELPEGQGVSGETGTESTAERSARFERDAL
                     EFLDQMYSAALRMTRNPADAEDLVQETYAKAYASFHQFREGTNLKAWLYRILTNTFINS
                     YRKKQREPQRSAAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKAALQAIPEEF
                     RIAVYLADVEGFAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYARERGLVPAGAGE
                     SDEAKGSGS"
     misc_feature    complement(17103..17117)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            complement(17293..17940)
                     /locus_tag="IE189_RS10045"
                     /old_locus_tag="GCM10010496_20420"
     CDS             complement(17293..17940)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571330.1"
                     /locus_tag="IE189_RS10045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20420"
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_189919926.1"
                     /transl_table=11
                     /translation="MSSETVVSTETARTEAGTARITWHHAARPRLVLALSHGAGGGIEA
                     RDLRALAAVLPAHGVSVALVEQPWRVAGKKVAPAPKTLDTGWRGIWPAVAAPGLPVISG
                     GRSAGARVACRTARELCAHAVLALSFPLHPPGRPERSRAAELLGAGVATLVVQGGNDPF
                     GRPGEFPAGGYELVEVPYGDHGFAVPKRAGVTGEQTLETVTAGVVRWVASLG"
     gene            complement(17942..18757)
                     /locus_tag="IE189_RS10050"
                     /old_locus_tag="GCM10010496_20430"
     CDS             complement(17942..18757)
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980380.1"
                     /locus_tag="IE189_RS10050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20430"
                     /product="SOS response-associated peptidase"
                     /protein_id="WP_189919928.1"
                     /transl_table=11
                     /translation="MCGRYAASRRPEDLAGVFEIERWEPEETLEPDYNVAPTKEVYAVL
                     DRPLKDADDKRPVRQLRKLKWGLVPSWSKTPEGGARMINARAETVHEKPSYRRAFTTRR
                     CVLPADGYYEWVTGVQERDLEVEGKKKRPRKQPYFVLPADGSVFAMAGLYEFWRDRTLP
                     DDHPQAWWATCSVITTEAETSPLAVAPAEGPHALADIHPRMPLMLTPDRWDAWLDPART
                     DADDLRCLLAPPPPGLMRAYPVSTAVSNVRNNGPELLKELEGPEEGTLF"
     gene            18815..19537
                     /locus_tag="IE189_RS10055"
                     /old_locus_tag="GCM10010496_20440"
     CDS             18815..19537
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992842.1"
                     /locus_tag="IE189_RS10055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20440"
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_189919930.1"
                     /transl_table=11
                     /translation="MESTAALALPDLWDRLVGTQSEPDLWVVIATAVAALAVVVPHTLW
                     RISRNAITIAHEGGHGLVALLTGRQLTGIRLHSDTSGLTLSRGKPHGLGMILTAAAGYT
                     APPLLGLGGAALLGAGRITLLLWVATALLLVMLVMIRNAYGALTVVLTGGTFLLVSWLA
                     GPQVQAAFAYAVVWFLLLGGVRPAFELQAKRSRGGAGDSDADQLSRLTHVPAGLWLFLF
                     HAVSLCALLGGGRWLLAL"
ORIGIN
        1 ggaggagttg tcgaacttgg cggtgtcgag gggggcgaag gcgcccttga ccatgtagcc
       61 gagcatctcg gtgttgccca tctcgaccac gtcgggcgcc ttgtcggtgg cgaggaccgc
      121 gtcgagcttg gcgttcttgt cgggccagcc gtagtactcg tggttgatct tgacgccggg
      181 gtgggccttc tgcaccgccg cgtcggccgc cttcaccagg tccggccagt tgttctgcgc
      241 gtcgacggtg agccagacgg tcagctcctt ggcgtcggtg cccttcgagt ccccactccc
      301 gctgtcgtcc ccgcacgccg cgatggagac catcatgccc gcgataccga tcgcggctat
      361 cagcttgcgc ttcacgccat cctcctcagg gatgccacac cccccgccca cgggccggga
      421 cctcgatctg gaccaatggt gtagaccagt gcgcagagct tggctcagac caataagcct
      481 gtcaagggtg gccgaacccc ctccgaacag ccgttatggg acctacatat gcaggaacct
      541 ttaagtaaga agccctcgaa aacatcggct ccggagggcg gctctccggt agaccatttg
      601 ccctggtgga ctagaccagc aaaggttgcg acggtataca gagggatcac ggaacggtgg
      661 cgcagcatcc cccgcgtccg tgccacgatg tgagccgcgg ccgacggcgt gtcggccatt
      721 tcggcatccg aagccgggaa ggcaggccat gagcaccgat gtcagcagtg cggagaacga
      781 gggtggggcg accgtccgta ccgcgcgtgt gcccaagtac taccgcctga agaagcacct
      841 gctcgacatc acggagacgc agtcgccggg caccccggtc ccgcccgagc gcacgctggc
      901 cgccgagttc gacacctcgc gcaccaccgt ccgccaggcc ctccaggaac tggtcgtcga
      961 gggccgcctc gaacgcatcc agggcaaggg cacgttcgtc gccaagccca aggtgtccca
     1021 ggcgctgcaa ctcacctcgt acaccgagga catgcgcgcg cagggcctgg agccgacctc
     1081 gcagctcctg gacatcggct acatcaccgc cgacgaccgc ctcgccgccc tgctcgacat
     1141 aacggccggc gggcgcgttc tgcgcatcga acggctgcgc atggccaacg gcgaaccgat
     1201 ggccatcgag acgacccatc tgtcggcgaa gcggttcccg gccctgcgca ggtcgctggc
     1261 caagtacacc tccctctaca ccgccctcgc cgaggtctac gacgtccggc tcgcagaggc
     1321 cgaggagacc atcgagacct ccctggccac cccgcgcgag gcgggccagc tcggcaccga
     1381 cgtgggcctg ccgatgctga tgctctcgcg tcactcgctg gaccaggagg gccggccggt
     1441 ggagtgggtg cggtcggtgt accggggcga ccgctacaag ttcgtggcac ggctgaagcg
     1501 gcccgccgag tagagggtct gtggagggcc ttccgctggg cttatccgtc acttacattg
     1561 cctgcgcatt acacctgtga tcaaggcgat cgagtgaggg gcggagccgc cgatgtcaga
     1621 gagcccggaa gtgaccaggg gaccggtggt gacgcctgtg cgcgtcgcca tcgccctgtg
     1681 tctgctcgcg cccttcgtgg cgatgctgtg ggtgggttcg tacgcgaagg tggacccgac
     1741 gttcatcggg atccccttct tctactggta ccagatgctg tgggtgccgc tctccgccgt
     1801 gctgaccgtg accgcgtaca agctgtggcg gcgtgaccag cgcgcccgcg ccaccgcccc
     1861 ggccgcctcc ggctccgccc cgaagggcgg tgcgtcgcgg tgaaggacgg cgtgaacggc
     1921 gtcgcgctcg gcgtcttcat cttcttcttc ctggccgtca cggtcatggg cttcctggcc
     1981 gcgcgctggc gcaaggccga gaacgagcac agcctcgacg aatggggtct cggcggacgc
     2041 tcgttcggca cctgggtcac ctggttcctg ctcggcggcg acctgtacac cgcgtacacc
     2101 ttcgtcgccg tacccgcggc gatctacgcg gcgggcgcgg ccggcttctt cgcggtgccc
     2161 tacacgatcc tcgtgtaccc gctgatcttc accttcctgc cccgcctgtg gtcggtgtcc
     2221 cacaagcacg gttacgtgac cacctcggac ttcgtgcgcg gccggttcgg ttccaagggc
     2281 ctgtcgctgg cggtcgccgt caccggcatc ctggcgacga tgccgtacat cgcgctccaa
     2341 ctggtcggca tccaggcggt gctggacgtg atgggcgtcg gcggcggcga gaacaccaac
     2401 tggttcgtga aggacctgcc gctgctgatc gcgttcggcg tgctggccgc ctacacctac
     2461 tcctccggcc tgcgtgcccc cgcgctgatc gcgttcgtga aggacacgct gatctacatc
     2521 gtcatcgcgg tggcgatcat ctacatcccg atcaagctgg gcggcttcga cgacatcttc
     2581 gccaaggcgg gcgaggcgtt cagccagacc aacccggcga cgggcaaacc gcgcggcgcg
     2641 ctggcaccgg cggaaccggg ccagtggacg tacgcgacgc tggcgctggg ctccgccctg
     2701 gcgctgttca tgtaccccca ctccatcacg gcgaccctgt cctcgcgcag ccgtgaggtg
     2761 atccgccgca acaccacgat cctgccgctg tactcgctga tgctgggtct gctcgcgctg
     2821 ctgggcttca tggcgatcgc ggcgggggtc aaggtcacca acggccagct ggcgatccct
     2881 cagctgttcg aggacatgtt cccgtcctgg ttcgcgggcg tggcgttcgc ggcgatcggc
     2941 atcggcgcgc tcgtgccggc ggccatcatg tcgatcgcgg ccgcgaacct cttcacccgc
     3001 aacatctaca aggacttcat caaaccggac gcgacaccca aggaggagac ccgcgtctcc
     3061 aagatcgtgt cgctgctcgt gaaggtcggc gcgctggtct tcgtcctcac catggacaag
     3121 acggtcgcca tcaacttcca gctgctgggc gggatctgga tcctccagac gttcccggca
     3181 ctggtcggcg gcctgttcac ccgctggttc caccgctggg ccctgctcgc cggctgggcg
     3241 gtcggcatgg tctacggcac cttcgccgcc tacggcgtcg cctccccgac ccagaagcac
     3301 ttcggcgggt cgtccaagga gatcccgggc atcggcgaga tcggctacat cggtctcacc
     3361 gcgttcgtga tcaacgtcgt ggtcacggtg gtgctgacct tcgtcctgcg ggcggccaag
     3421 gcgcccgacg gcgtcgacga gacgaagccg gaggactaca cggcggacgc gggcgacccg
     3481 ggcgtccagg tggagctgcc gccggcgacc gcgggcacgt cccactagca tccgccggcg
     3541 cgggccccgc gggtccgcgt ccggcacggg cgggccgtcg gagcgatccg gcggcccgcc
     3601 cccgtgcgcg gggagcgcac cgcccggcac accctccgtc gggttccggc gggatcactc
     3661 tgctcgcccg tcagttgacg ctccggaacc agcgcgacac aacatctggg ggtggcgtga
     3721 cgggcgagca caagatgtat gctcatgctc gctgtcgccg caggggaatc cggtgcgaat
     3781 ccggaactgt cccgcaacgg tgtactcgcg tgcatccata cccgtatgcg cacgcctgtt
     3841 cagtccgagg tcctgccgac agcgcgcccg gccgtccggt ccgggtgccc tgacgtccgg
     3901 gtctcgtgga gtgggccggt ggacgcgacg cccccgcgcg ctcgtgtgct gccccctgcc
     3961 ccgcgcaagg cccacgccga gcgagggaga gccccacgtg accatcgcgc cagccggccc
     4021 ggttccagcc accgaaccgg agtccgacgg tcccggcacc gcgttgctgc ggaccctgac
     4081 cgagctgacc gccgacctgc ccgacgccga ccccggccgg gtcgccgccg cagcgctgcg
     4141 cggccggtcc ggccgggccg acgaggcgga gctgcgcgag ctggccacgg aggcggccgc
     4201 cggcctgatc tcggaggacc ccgcctactc gaagcttgcc gcccggctgc tcaccgtcgg
     4261 catcgccgcg gaggccgcct cccagggcgt cacgtcgttc accgggtcgg tcgccgtggg
     4321 ccaccgcgag ggcctcgtcg ccgaccgcac cgccgagttc gtgcgcgtcc acgccgcccg
     4381 cctcgacgcg ctgatcgacg agcgggccga cgaccgcttc ggctacttcg gactgcgcac
     4441 cctgcacagc cgctacctcc tgcggcaccc gatcacccgc aaggtcgtcg agacgccgca
     4501 gcacttcctg ctgcgcgtcg cctgcggtct cgccgacgag ggtccctcct ccggggaaga
     4561 cacgccccgc gcgctggacg aggtcgccgc gctgtacggg ctgatgagcc gtctggacta
     4621 cctcccgtcc tcccccaccc tcttcaactc cggcacccgg cacccccaga tgtcgtcctg
     4681 ctacctcctc gactccccgc tggacgagct ggactccatc tacgaccgct accaccaggt
     4741 ggcccggctg tcgaagcacg cgggcggtat cggcctgtcg tactcccgca tccgttcccg
     4801 tggttcgctg atccgcggca ccaacgggca ctccaacggc atcgtcccgt tcctgaagac
     4861 gctggacgcc tcggtcgccg cggtgaacca gggcggccgg cgcaagggcg cggccgcggt
     4921 gtacctggag acctggcact ccgacatcga ggagttcctg gagctgcggg acaacaccgg
     4981 tgaggacgcc cgccgtacgc acaacctgaa cctcgcgcac tggatcccgg acgagttcat
     5041 gcgccgggtc aacgcggacg agccgtggtc gctgttctcc ccggccgacg tgcccgagct
     5101 ggtcgacctg tggggcgagg agttcgacgc ggcctaccgg tcggccgagg cgaagggact
     5161 ggcgaagaag accatccccg cccgtgacct ctacggccgc atgatgcgca ccctcgcgca
     5221 gaccggcaac ggctggatga cgttcaagga cgcggccaac cgcaccgcca accagacggc
     5281 cgagccgggc catgtcgtgc actcctccaa cctgtgcacc gagatcctcg aggtcaccga
     5341 cgacggcgag acggccgtct gcaacctggg atcggtgaac ctgggcgcgt tcgtcgacac
     5401 ggcggccggc accctcgact gggagcggct ggacgacacc gtccgcacgg ccgtcacctt
     5461 cctcgaccgg gtcgtcgaca tcaacttcta cccgaccgag caggcgggcc ggtccaacgc
     5521 gcgctggcgc ccggtcggcc tcggcgcgat gggtctccag gacgtcttct tcaagctgcg
     5581 gctgccgttc gactcccccg aggcgaaggc cctgtccacg cgcatcgccg agcggatcat
     5641 gctcgccgcc tacgaggcct ccgccggcct ggccgaacgc aacggcccgc tgccggcctg
     5701 ggagaagacc cgtacggcca ggggtgtgct gcacccggac cactacggcg tcgagttcac
     5761 ctggcccgag cgctgggcgg ccctgcgcga gcggatcgcc cggaccggca tgcgcaactc
     5821 cctgctgctc gccatcgcgc cgaccgccac catcgcgtcc atcgcgggcg tgtacgagtg
     5881 catcgagccg caggtgtcca acctgttcaa gcgcgagacg ctgtccggtg agttcctcca
     5941 ggtcaactcc tacctggtgc aggacctcaa ggagctcggc gtctgggacg cccgcacccg
     6001 tgaggcactg cgcgactcca gcggctcggt gcaggacttc gcctggatcc cggccgacgt
     6061 gcgcgccctg taccgcacgg cgtgggagat cccgcagcgc ggtctgatcg acatggccgc
     6121 cgcccgcacc ccgtacctgg accaggccca gtcgctgaac ctgttcctgg agacgccgac
     6181 catcggcaag ctctcctcga tgtacgccta cgcctggaag tcgggtctga agaccacgta
     6241 ctacctgcgc tcccgcccgg cgacccggat cgcccgcgcg gcccaggccc aggccccggc
     6301 cgcagtcccc ctccagcagg tgaccgagcc cgacgccgtc gcctgctccc ttgagaaccc
     6361 cgagtcctgc gaggcctgcc agtaatgacc agcgcacccg agaagaccga gaagaacctg
     6421 ctcgacccgg gcttcgagct gaccctgcgc cccatgcgct acccggactt ctacgagcgg
     6481 taccgggacg ccatcaagaa cacctggacc gtcgaggagg tcgacctcca ctcggacgtc
     6541 tccgacctgg cgaaactgtc cgagggcgag cagcacatga tcggccggct ggtcgcgttc
     6601 ttcgcgacgg gcgactcgat cgtggcgaac aacctcgtgc tgacgctgta caagcacatc
     6661 aactcccccg aggcgcgcct gtacctgtcg aggcagctct tcgaggaggc cgtccacgtc
     6721 cagttctatc tgacgctgct ggacacctac ctccccgatc cggcggaccg cgccgcggcc
     6781 ttcgccgccg tcgagaacat cccctcgatc cgggagaagg ccgagttctg cttcaagtgg
     6841 atcgacgagg tcgagaagct ggaccggctg gagagcaagg ccgaccgccg gcgcttcctg
     6901 ctcaacctga tctgcttcgc ggcgtgcatc gagggtctgt tcttctacgg cgccttcgcg
     6961 tacgtctact ggttccgcag ccgggggctg ctgcacggtc tcgccacggg caccaactgg
     7021 gtgttccgtg acgagacgat gcacatgagc ttcgcgttcg aggtggtcga cacggtgcgc
     7081 aaggaggagc cggacctctt cgacgaccgg ctccaggagg aggtgacggc catgctgcgg
     7141 gaggccgtgg acgccgagct ccagttcggg cgcgacctgt gcggcgaggg gctgccgggc
     7201 atgaacaccg actcgatgcg gcagtacctc gagtgcgtcg ccgaccagcg gctgacgcgg
     7261 ctcgggttcg ccccggtgta cggctcggag aaccccttct ccttcatgga gctccagggt
     7321 gttcaggagc tgaccaactt cttcgagcgc cgtccctcgg cgtaccaggt ggcggtggag
     7381 ggcaccgtcg acctggacga ggacttctga tcctcctgct ccccgcgggc ctcctgggcc
     7441 tccctgatct gccggtcggc gcgccggtcg cgtgcgacgc cgaacgcgga cgggaggacc
     7501 aggaggacga ggatcccgaa ggtcaggagc attccgatga ggccttcgat ctggttcgtg
     7561 ttcatggaca ccagtctccg gccggacact cctgaccggg agtggcagga ctgccgcaca
     7621 tcttcaaatt cctgccatcg gcggggcaca ctggccgcat gctgaaaaac gtggccgcga
     7681 tcctcctgga cggtgtgcac cccttcgaac tgggcgtcgt ctgcgaggtc ttcgggatcg
     7741 accgcagtga cgaggggctg cccgtgtacg acttcgccgt cgcctcggcg gaggggccga
     7801 cgctggccac ccgcgccggg ttcaccctga gcaccccgca cggcctggag cggctggaga
     7861 acgccgacct gatcgccgtg ccggccgggg acacctacgg caggcgggac ttcccgccgg
     7921 agctgctcga cgccctgcgc cgggccgtcg accggggcac ccgggtgctg agcgtctgct
     7981 ccggggtgtt cgtgctggcc gcggcgggac tgctggacgg gcggcgctgc gcggtgcact
     8041 ggcggcacgc cgagcagctg gcccggcagt acccgcgcac gaccgtggaa ccggacgtgc
     8101 tctacgtgga cgaggacccg gtgatcacct ccgccggcac cgccgccggg atcgacgcct
     8161 gtctgcacct ggtccgcaag gagcagggcc ccgaggtggc caaccggatc gcccggcgga
     8221 tggtggtgcc gccgcaccgg gacggcggcc aggcccagta catcgagcgg ccgctgcccc
     8281 ggtcgcggtg cgacaccgtg ggcgaggtgc tcgcctggat ggagcagcac ctcgaccagg
     8341 agatcacggt cgaacggctc gcggagcgcg cccacatgtc cccgcgcacc ttcgcccggc
     8401 gtttccagca ggagaccggg accaccccct accgctggct gctgcggcag cgggtgctgc
     8461 tggcccagca cctgctggag gcgacggacg agacggtgga cgcgatcgcc tggcgcgccg
     8521 gtttcggcac ggccggcgcc ctgcgccacc agttcgtgca ggcgctgggg acgaccccca
     8581 acgcctaccg gcgcacgttc cgcggcccgc aggccgcggc ctgacccccg tccctacccg
     8641 ggtattgccc gcagccgcag ccggcggggc cgcagggtga tgccgatgtg cgtccggttg
     8701 tcggaaccgg gcgccggctc gaaacggaag gcggaggcga ggaccgcggt gatcagcgtc
     8761 agctcggcca tcgagaaatg gtcgctcgga cacttgcggt taccgacacc gaacggcgcc
     8821 atggcgtact tgggcacccg cgcggagccg ccgggcagcc agcggtccgg ggcgaactcg
     8881 gtgtgccgct cgtacgaccg cggatcgcgc tgcacggcgt acgggctgta gacgatgtcg
     8941 gcaccggccg gaatgcggta gccgccgagc tcggtctcgg tcaccgcgcg ccgggtcaat
     9001 atccatacgg cgggatacaa ccgcatggtc tcgaccacga cattggcggt gtgctggagc
     9061 tttcggacgt cgtcgaatgc gacgggccgg tcgccgacga cgtttttcac ctcttcgcgg
     9121 atcttgtcca cctgatccgg gtgctcggtg aggacgttga gcagcgacat gaccacagag
     9181 ccggcggttt cgctgcccgg ggtgagtatc gcgatgacct ggtcgtggat ctcctgttcc
     9241 ccgatcgggt cgccattctc gtccacggcc tccagcaaag ccgtcagcaa atcgtccggc
     9301 ttttgaccgg atgcccggcg gtcggcgacg atctcgtcca ccagccgatg cagatcggcc
     9361 aaggcccggt tgaattcgcg gttggccgga atcggtaccc gataaagcgg accgaggggc
     9421 accaccatgc gctggtacat accggcgaac agcgtggcga gcgcggaggt gatgcgctcc
     9481 gaccgggcgt ccatatagct gccgcgcatc aggcagcgcg ccgagatgcg cacggacacc
     9541 cggaaggcct cggccgtgac gtcgacgacc tccgcgccgc ggaagcggtc gacgagggcg
     9601 tgggcctcct cctccatgat cggcccgtag cccgggatgg cgtcgagccg gaacgcgggc
     9661 tggatcgtgc gccgctggcg gcggtggagc gggccgttgg cggtggccac gccctccttg
     9721 ccgagcaggc tctccaggga ctcccacagg ggccccgaga tgatgtagtc cgggctcagc
     9781 gcgagagccc cggtgagctc aggcgaggtg acggcgtaca ccgtcttggg gcccagccgg
     9841 aggcggacga cgtcgccgtg ctcgcgcagc cgggccagga aggccagcgg gtcgcggacc
     9901 agcttccagc cgtgcccgag gagcggaagc ccgccaccgg ccagcggtgg ctcgctcggt
     9961 ccgggcgtct tgggggtcgt gggtttcatc gactcgacgg tcatttctca cctgccgctt
    10021 cgttgttgac gtacgggggc gtggaccggt cgtcccagct gtcgaccatg taccggccgg
    10081 actcgtggtg gaaccagtag acggaactga accagttccg catattgccg acgcaggcgc
    10141 gaaccgcggc acttgtttcg tttccgcgta cggtgccgtc ggcgagccgg tcggcgagca
    10201 gcaggacgtc cttctcggcg gcgaggaacc cggaaatgca ttccccgaca cggcgcctga
    10261 gttcttcgac cgcctcttcg agagtcagcc cctcatgggt gatgagactg attccgagat
    10321 tgtgcacctc atcgcccgct atttccttcg gcaacgagca gagatcgttg taccaggcgg
    10381 cgaattcctg gcacagcagg gccgcgcgcc gataggcggg gtgtttcctc gcccggtccg
    10441 ggagttcggt ccccgcactg agttccagaa ggtcggtcca gatccagtgc gcgaaggtga
    10501 gccggcgcag ggccaggtat tcctcgacgc ccgggacacg cccttcggtc cggttgtgga
    10561 attcccggtc gtaggcgtcg atgaccgcgt ggaagtgccg ggcgaaccgg gcgttccagg
    10621 tgccgggaag gaaggagtac agccggccca cgctgtccgc gagcccggcg accagcggat
    10681 cggaatggtg caggtgctcg gcggggaagt ccagggccgc gtgcaagcgg aacctcagcc
    10741 gccgccagga ggaggaccgg ccgtgcacga cgtcgcggtc gtgccggtcg tcccagacga
    10801 agaaccacgc actgtagtcg gcgatcgcct gcatcacctc gtcgggtgcg ccgaggtaga
    10861 agcccgccat caggtcggtg tagcaaagtc cgtcggcata ttctgcgacc ttgtccgccg
    10921 gcatcaaccg cttttccagc agccaggagc gcgtcctctc ctgcaactgg ggccaatacg
    10981 gatgcagtcg ccgggaaaac gccgcctcga tgaccggaag agagagcgag ggagggaccg
    11041 cgggcgcggc caccgtcgca gtggtgctgt atgtggtgct gtatgggaaa gctggcacga
    11101 acaacccctc tcagccgcca gtgggcacac gcccctcgac ccgtgccggg cgtgcgccgt
    11161 tgcgtatccc cgcacttccc attcagcact acaactgacc gttctgggaa cggatttgct
    11221 ccattcacca ccccaacatg ccgagaatcc gcccctgggt gactggttac ggatcagcag
    11281 atgtgcagta gttgtgcgta aacgatcgaa cgtctgtcgg acacacgaac gacgcccaga
    11341 cgggaggatc ccggccgggc gtcgtcatgg tgcggagggg ctcagtcgtt ggcgaccacg
    11401 ggataccggg gctcgttctc ggccatctgc cgcagggcgt ccttgcgttc gcgcttggac
    11461 agacggtcga tgtagaggta cccgtacaga tggtccgtct cgtgctgcaa acaccgagcg
    11521 aagtacccgg tgccgcgtac cttgatcggg ttgccccgct cgtcctgtcc ggtcacctcg
    11581 gcgtagtcgg ggcgggccag cggcgcgtac gcggtcggca ccgacagaca gccctcgttg
    11641 ctgtcgtcca gccggcgccg ctccgcgggc agctcgacga gccgggggtt gcagacgaca
    11701 cccgtgtgcc ggacaccgtc gtcgtcgggg cagtcgtaga cgaagacctt caggtcgacg
    11761 ccgatctggt tggcggccag gcccacgccc tccgcggtgt gctgcgaggc gaacatgtcc
    11821 gccacgagct gccgcagctc gtcgtcgaac tcggtgacgt ccctgcactc cttgtgcagc
    11881 accgggttgc cgacgacggt gatcggccgc gaggtgccgg cctcacgcca ggtcagctcg
    11941 cgcgcctccg cctccccggt gtcgatgacg aagccctcgt cgtccacggg gagcacgccc
    12001 gcgtgctgct gatcggtgtc ctgctgcgcc atgaccgacg atgccttcct caaacagaca
    12061 gggggtgaat gctcgataca gggtacgggc agcgcgcacc tgcggggcgc ggggaacagc
    12121 gcgaccagcc acgacgaaca cgcggccgaa cgcggtcagc agacctcttc cagatcccgc
    12181 cagtcccggg agtcgggact gtcggcgacc cacccgtcca gcagcccccg gacgagcgag
    12241 gccggggcgg ccacgccgca ctcccgctcg ggcacccaca gctgcccgtc ggtacggtgc
    12301 ccgagcggcc cggggtgccc cggctcactg tggtcgtgcg ggtccaggtg ctcgccgtcg
    12361 ccctcgtcgg acggcatccg cgactccgag cacatccggc acagcagccg caccgacgac
    12421 gaccagtcct ccgcggcgaa gcccgcgtcg gccgccagct gctccagcgc gtcccggtcg
    12481 gactcggtgg ccgcctccag gaggaccacc caggtcggca cgggcgacgg cgcccacagc
    12541 tcgatctcgt cgaataccgg gtaggagtgg ccggtcgccg tggtgcgctc gccgtgcggc
    12601 accccgtcgt gcaggacgac ctcaccccag cgccgccccg acgagggcag cgggatcgac
    12661 aggacctcca tgcgggcggg gtccagccgc cgcccccaga ccacctctgc ctcgccctcg
    12721 ggcgacagcc gcaccgccgc gctgcccagt tccatgccca ccggctcgcc cgcgcccgtg
    12781 gcctcgcccg gtacccgcag cccgtacgcc tgccaggcgc ggcgggccag cggccagtcc
    12841 tggagggcgg tggcggcgat gccgacgttc caccagtcgg gggcgccggc ctcgcggtcc
    12901 aggagggcca ccgcacgcag ccccgcggtg cgggcctgct cccagtcgtg ccggaacttg
    12961 tgcagcaggg cgaggttgaa ccaggactcg gacagccagg gttccaggtc ggcggcacgt
    13021 gtcagcagcg cgcccgcgtc ctcgtaccgc ccgtcgccga tcagcgtgaa cgcgcggtcg
    13081 gtggcctgcc gccaggaggc ggagggccgg tgccgtccct tgccgaagat cctcacgatt
    13141 cccgcctgcc agttccgttc tgtgggctgg ccagtgcccc cggacactct cttcctcgca
    13201 tccaaccacg tgtggccgga gggccgctca ttacccatgg gttacccagc cccggccaag
    13261 gtcagacagc ccacgagtcg cccgccacca ccctgcccga ggcgcccccg ggaccggagg
    13321 ccggggggtg gaccccggcc tgcgcccccg tcctgcgaag caccgcggcc agggcctcga
    13381 ccacctcggg cgcgtactcc cggccggtgc cgaggcgcag ctcctccagg gcggcgagcg
    13441 gcccgccggg acccctgccc cgggccttct cctcgtatgc gttcaccacc cggacgatgc
    13501 gggcggccgg cggctgctcc gggtagggat cggcctgccg ctcgacgacc gcggcgaccc
    13561 gggcgtccgc cccggtctgc cggacgacgg ccccgcccag cagggcgatc ctgcgctgct
    13621 gcgccaccgg cagccccgcg gtggcgccgt ccgggaccgg gtcgacgagg ctgagctggc
    13681 cgatgtcgtg catgagggcc gcgtactcca ggacggtcag ctcgggctcc ggcagcccca
    13741 ggtcccggcc caccgcgtgg ctgagggcgg cgacccgccg ggcgtgcccg gccggggtgt
    13801 acccggcgat ctcggtggcg cgggccagcg aggcgatggt ctgccggtag gtcgcccgca
    13861 ccgccgcgtg ccggcgcagg gacagctggg tgagcagcag cggcaccgag aacaccggca
    13921 gcgcccagag cccgacgacg gccaccgcga gcgccatcac cgcccccgtc gcgcacaccg
    13981 ccgagccgat ccccggcagg ccccgcagct cgtcgcgcag ggtcggggcg aacggccagc
    14041 cggtgcggga gcgggccagc acggcgacga ccaccgtgtc gcacaggacg gtcaggacca
    14101 gcagggcgag cagcagcagg gtgtgggcgg ggccgctcca gccgtcgaac accccgcggt
    14161 tgtggagcgg ctggaagcag acggcggcga acccgacggc cagcacccgc cggaccaggt
    14221 ggtcgaggac gggtccctcc ccgcgggcca gctgcggcac gccgcccagc agggaggcgg
    14281 cggccacgac cgtcacgacc tgggcgaccc cgtgatgcgt gggatgcccg gcgtgcgcac
    14341 cgacgagggc gtaggccagc gatcccgcgg cgcccagcgg cgcggcctcg cgcagcgggg
    14401 gtccgcccgg cggacgggcc agctcgccga cggccaccag gaccccgaag gcgagggcga
    14461 ccgggcgttc ctcgacgccc gtcgcgaacg tgacgaggag ggagccggcg acgaggaggg
    14521 cggcgacggc gtggagcgcg aggggggaac ggcgggcggt caccggcgcg ctcccgaccg
    14581 gtcgtcgggg gtgcgggcgg gcgggggcgc cgccggccgg gtctcgtcgg ccgtcaccac
    14641 cgggtgccag ccgtcccgct cgacgacgtc ggccagtgcc gcgaccatcc gggggtcgaa
    14701 ctgggccccg gcgcagcgcc gcagctcctc cagggccgcg cccaccggcc gggccctgct
    14761 gtaggagcgg gtggacgtca tggcgtcgaa ggcgtccgcg acggcgacca cgcgggccgg
    14821 ctccgggatc tggccgcccg agagaccgta ggggtagccc gtgccgtcga ggcgttcgtg
    14881 gtggtgcagg atcgccgagc gggcctcccc gaggaaggcg atcccgcggg tgatctcgtg
    14941 gccgtactcg ggatgcagtt cgatcacccg tcgctcctgc ggggtcagcg gcccgtcctt
    15001 gcgcaacagc cgggtgggta cgccgagttt gcccacgtcg tgcaggatcc cggcgaagcg
    15061 gagcatctcg atccggctct cgtccatgcc cagttcgcgc gcgatcagca ccgaggcctg
    15121 gccgacccgc tcgctgtgcc cgcgggtgta gccgtccttg atgtcgacgg cctgcaccag
    15181 ggcccggatc gtcgcctggt gggcggcgcg ctcgcggtgg tactgcgcga acacccacca
    15241 cgacacggcc gtcgggaaca gcacgaggag ggcggccaga ggcccgtacg ggctgctcca
    15301 cagcacggcc gtcatcagtc cggcgagccc gtgcacggcc agcggcgcca gggaacgcag
    15361 gaacagtccc cggcacaccc gccgcagcgg caggccctcg gcgagcgccc gcatcccgcc
    15421 gttcagcagg gcgagcgcgg cgcagaacac cagcacggcc gcgcccgccg gcaccagcgc
    15481 ccgcggcagt tcgcaggcgg ccacggcctc ccgtccgccg agcgccccgt gcacgtggga
    15541 agccgcccac acggcgaggg acgcctgggc ggcccgccag agcctgcgca gcgcgaaggg
    15601 gcgccgttcg acgtgcgaga acagcgcccc tggcagcggg acgagggcgg ccgcggccgg
    15661 ttcgagcagg aacgccccgg ccagcagcac ggggtgcagg gtgccggcga accggcggcg
    15721 ggcgatccgc tccccgccgg cgtacagccc ggcgagcagg gcgacggccc accacggggt
    15781 gcgcgggccc ggcgggagcg tgcagagcag tgagccgagg gcggcacagg cggcgtatcc
    15841 gcgtgcccgc gccggaattc cctccatcga cgcctccccc agccgtgcct gtccggctca
    15901 ggagcctagg acggccgggg gtgggtctgc gggcgtatca cccgcggatt agcacattcg
    15961 ggtgatggcg gggccggaag ggactcagct ctcctgggtc gtcgccgtca cgtcgtgctc
    16021 ggggacggtc tgtccggagc ggatcaggtc gatccggccc atcaccttcg cccgcaggtc
    16081 ggtcggcacg tcgtcactgc cgcagcaccg cttgaccagc ttcttcacgg cctcctccag
    16141 cccgtacttc tccaggcagg gggagcactc ctcgaagtgg tgctggaact tgtcccggtc
    16201 gagaggaggc atttcgctgt cgaggtactc gtacaggtgg tcgaggacct caccgcagtc
    16261 cgtctcgtgc ggatctccgc agctcatgag cccgagcctt tcgcttcgtc cgactctccg
    16321 gcaccggccg ggaccagccc gcgctcacgg gcgtagtcct cgagcatgcc gcgcagttga
    16381 cggcggcccc ggtgcagccg ggacatcacc gtaccgatgg gtgtccccat gatgtccgcg
    16441 atctccttgt acgcaaagcc ctctacgtcc gcgagataca cggcgatgcg gaactcctcg
    16501 gggatggcct ggagcgccgc cttcacgtcg gagtcgggca ggtggtccag tgcctgcgac
    16561 tcggcggagc gcagacctgt ggacatgtgc gactcggcgc gtgccagctg ccagtcctcg
    16621 atctcctcgg ccgcgctgcg ctggggttcg cgctgcttct tgcggtacga gttgatgaag
    16681 gtgttcgtga ggatccggta cagccaggcc ttgaggttgg tgccctcacg gaactggtgg
    16741 aaggacgcgt acgccttcgc gtaggtctcc tgcaccaggt cctcggcgtc cgccggattg
    16801 cgcgtcatgc gcagggcggc cgagtacatc tggtcgagga actccagcgc gtcccgctcg
    16861 aagcgcgcgc tgcgctccgc ggtggactcc gtgcccgtct ccccgctcac gccctggccc
    16921 tcgggcagct ccgcctggcc gttgtcggtc cctgcgtcgg taccggtgac cggacccacc
    16981 tcctcaagat cgcgggtgga accgaaaccg atcccactcg aatcggagga tagacgacta
    17041 cccgcgcccg ccgccgctcc aatagaagcg gtcctggccg cgtgcagcac cgtccagtcc
    17101 agatcgacgc gggtgctgcg gctcgattcg gactgcgccg gacccgaccc gcccacgggg
    17161 tggtgatacg tggcgggcgg gcagatggtc gaacccatgc ggcggacttc ctctcccact
    17221 gacttcggtg cctgttgtcc agcacctatg tccgcctcaa cagcgtccgg tcgcgcggca
    17281 ttccccggcc gttcacccga gtgacgcgac ccaccggacg actcccgcgg tgacggtctc
    17341 cagggtctgc tccccggtca cgccggcccg cttgggcacg gcgaacccgt ggtcgccgta
    17401 cggcacttcc acgagttcgt acccgcccgc cggaaactcg ccgggtctgc cgaacgggtc
    17461 gttgccgccc tgcacgacga gggtcgccac ccccgccccg agcagctcgg cggcccggga
    17521 ccgctccggc ctgcccggcg ggtgcaacgg gaagctcagc gccagcacgg cgtgcgcgca
    17581 gagctcgcgg gccgtgcggc aggccacccg ggcgcccgcc gagcgcccgc ccgagatcac
    17641 cggcagcccg ggggcggcca cggccggcca gatgccacgc cagccggtgt ccagggtctt
    17701 cggcgcgggc gcgaccttct tgcctgccac ccgccacggc tgctcgacca gggcgacgct
    17761 caccccgtgg gcgggcagca ccgcggccag cgcccggaga tcgcgagcct cgatcccgcc
    17821 gcccgcgccg tggctcaggg cgaggacgag ccgcggcctc gccgcgtggt gccaggtgat
    17881 gcgggcggtt cccgcctcgg tccgcgctgt ctcggtgctc acgaccgttt cgctgctcac
    17941 gtcagaagag tgtgccctcc tcgggcccct ccagctcctt cagcagctcc ggaccgttgt
    18001 tgcggacgtt gctgacggcc gtggacaccg ggtaggcgcg catcagtccg ggcggcggcg
    18061 gtgcgaggag gcagcggagg tcgtcggcgt ccgtgcgcgc cgggtcgagc caggcgtccc
    18121 agcggtccgg ggtgagcatc agcggcatac gggggtggat gtcggcgagg gcgtgcgggc
    18181 cctcggcggg agccacggcg agcggggagg tctcggcctc ggtggtgatc accgagcagg
    18241 tcgcccacca ggcctgcgga tggtcgtcgg gcagggtccg gtcccgccag aactcgtaga
    18301 gcccggccat cgcgaagacc gagccgtcgg ccgggagcac gaagtagggc tgcttgcggg
    18361 gccgcttctt cttcccctcc acctcgaggt cgcgctcctg gacgccggtg acccactcgt
    18421 agtagccgtc ggcgggcagc acgcaccgcc gggtggtgaa ggcacgccgg tacgagggct
    18481 tctcgtggac ggtctcggcc cgcgcgttga tcatccgcgc accgccctcg ggggtcttcg
    18541 accaggaggg gaccagtccc cacttcagct tccgcagctg ccgaaccggg cgcttgtcgt
    18601 cggcgtcctt caaggggcgg tcgaggacgg cgtagacctc cttggtcggc gccacgttgt
    18661 aatcgggctc cagggtctcc tcgggctccc accgctcgat ctcaaagact cctgcgagat
    18721 cctcgggcct gcgactcgct gcataccgtc cgcacatacg tgccacactg ccagacttcc
    18781 tgagccgaaa gaccgaaagg gaccaccaca cgacatggag agcaccgccg ccctcgcgct
    18841 gcccgatctg tgggaccggc tcgtcggcac ccagtccgag cccgacctgt gggtggtgat
    18901 cgccacggcg gtcgcggccc tcgcggtcgt cgtgccgcac accctgtggc gcatatcccg
    18961 caacgcgatc accatcgccc acgagggcgg tcacggtctg gtcgccctgc tgaccggccg
    19021 gcagctgacc gggatccggc tgcactcgga caccagcggt ctgaccctga gccgcggcaa
    19081 gccgcacggg ctcggcatga tcctcaccgc ggccgccggc tacaccgctc ccccgctgct
    19141 cggcctgggc ggcgccgccc tcctcggggc cggccgcatc accctgctgc tctgggtggc
    19201 gacggcgctg ctgctcgtga tgctggtgat gatccgcaac gcctacggcg cgctcaccgt
    19261 ggtcctgacc ggcggcacct tcctgctggt gtcctggctg gccggaccgc aggtgcaggc
    19321 ggccttcgcc tacgccgtgg tgtggttcct gctgctgggc ggcgtacggc ccgccttcga
    19381 actccaggcg aagcgctcac gcggcggcgc gggcgactcc gacgcggacc agctgtcccg
    19441 gctgacccac gtaccggcgg gcctgtggct gttcctcttc cacgccgtga gcctgtgcgc
    19501 gctgctgggc ggcggcaggt ggctgctggc cctgtgacac gaggccgacc gcggccgcca
    19561 caggggccgc ccggcggcgc ggggcgaggc cgggacgggg gcgcaaagca ggacgtcggc
    19621 ggggccggga cagggcgcag ggcgcgacgg gggcgccggg cggaacgtag gccgcccttg
    19681 cacgccccct ggccgggccc ggctgtgacg caccggacgc cgacctggcg ccgggccgga
    19741 cggcgggccg gcgccagcca gacgccgggc ccgaccgcgg ccgggcgccg agccggaccg
    19801 cgggacggac gacagccggg cgccgggccg accactaaag tggggcccat ggccccgaac
    19861 cccgcacaca ccgccctctg gcccgccccg cacgcgagcg aggccgtcgc cgcgacggtc
    19921 cacgtaccgg ggtcgaagtc cgtcaccaac cgcgccctcg tcctcgccgc cctcgcgtcc
    19981 gagcccggct ggctgcgccg ccccctgcgc tcccgcgaca ccctgctgat ggcgggcgcc
    20041 ctgcgcgcga tgggcgtcgg catcgaggag acggtgtcgt cgagctccgc cggcgccggg
    20101 ggccccgacg ccggcggcga ggcctggcgg gtgctgcccg cgggtctgcg cggaccggcc
    20161 acggtcgacg tcggcaacgc cggcacggtg atgcgcttcc tgccgccggt ggccgccctc
    20221 gccgacggtc ccgtccggtt cgacggtgac ccgcgcgcct acgagcgtcc cctgaacggc
    20281 gtcatcgacg cgctgcgcgt cctcggcgcc cgtatcgacg acgacgaccg cggagcgctg
    20341 ccgctgaccg tgcacggctc gggcgcgctg gacggcggca cggtggagat cgacgcctcg
    20401 tcctcgtcgc agttcgtctc ggcgctgctg ctgtccgccc cccgcttcaa ccagggggtc
    20461 gaggtccgcc acacgggctc ctccctgccc tccctgccgc acatccggat gaccgtcgac
    20521 atgctgcgcg cggtgggcgc gcaggtggac accccggagg cgggcggcga gccgaacgtc
    20581 tggcgcgtca ccccgggcgc cctgctgggc cgggacctga ccatcgagcc ggacctgtcc
    20641 aacgcccagc cgttcctggc ggcggcgctg gtgaccggcg ggcgcgtcat gatcccggac
    20701 tggccggccc acaccaccca gccgggtgac aggctgcgcg agatcttcac cgagatgggc
    20761 ggttcctgcg agctgaccga ccacggcctg gtcctcaccg gctcgggctc gatccacggc
    20821 atcgacgtcg acctgggcga cgtgggcgag ctgaccccgg gcatcgcggc cgtcgccgcc
    20881 ctcgcggact cgccgtccac cctgcggggc gtgtcccatc tgcgtctgca cgagaccgac
    20941 cggctggccg cgctgaccaa ggagatcaac gaactcggcg gcgacgtgac ggagaccgcg
    21001 gacggtctgc acatccgccc gcggcggctg cacggcggga tcttccacac cta
//
