LOCUS       NZ_BMSI01000003        21059 bp    DNA     linear   CON 02-AUG-2024
DEFINITION  Streptomyces asoensis strain JCM 4185 sequence03, whole genome
            shotgun sequence.
ACCESSION   NZ_BMSI01000003
VERSION     NZ_BMSI01000003.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces asoensis
  ORGANISM  Streptomyces asoensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 628564)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014649075.1-RS_2024_08_02
            Annotation Date                   :: 08/02/2024 04:45:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,813
            CDSs (total)                      :: 7,736
            Genes (coding)                    :: 7,563
            CDSs (with protein)               :: 7,563
            Genes (RNA)                       :: 77
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 53 of 173
            Pseudo Genes (incomplete)         :: 140 of 173
            Pseudo Genes (internal stop)      :: 10 of 173
            Pseudo Genes (multiple problems)  :: 28 of 173
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:21:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 212330
            Orig. end                         :: 233389
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMSI01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21059
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21059
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21059
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11059](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11059)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            62..1024
                     /locus_tag="IE189_RS09820"
                     /old_locus_tag="GCM10010496_19940"
     CDS             62..1024
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061477.1"
                     /locus_tag="IE189_RS09820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_19940"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_189919843.1"
                     /transl_table=11
                     /translation="MTASSTRRTTAARTRLAAVGSLAVAGALLLSACGDQTDSGGSSSE
                     SSSGADKAPLFSKLPADIQKAGVIKVGTNAEYAPMESVEGGKIVGVDPDIAAALGKELG
                     VDFQFTSGGFDTLITAVNTGRYDIAMSSITDNKQRQEGLDDSGKKLGTGVDFVDYFTAG
                     TAIYVQKGNPKGIKTIDDLCGQTVAVQRGTTYEEALQAQSKTCTGSGKKALKIESFEND
                     TEAQTRVKSGGAVAGVNDYPVAVDMARKAGGGNTFEVLDKQYEAAPFGIVVNKKNTQLR
                     DALKEAVDAIIKDGSYQKVLEKWGAESGAIKASAINGGK"
     gene            1064..2035
                     /locus_tag="IE189_RS09825"
                     /old_locus_tag="GCM10010496_19950"
     CDS             1064..2035
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020130737.1"
                     /locus_tag="IE189_RS09825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_19950"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_189919845.1"
                     /transl_table=11
                     /translation="MTDKLDKSSAGGAPPEDTPPVAKGPAFSGPPETIKAIPVRHYGRW
                     VSAVIVVALMVLLVNAFANGDIQWSTVGDQLFNSTVIAGAGRTLLISVLSMVLGVVLGV
                     LLAVMRLSKNPVTSTVAWLYIWFFRGTPVYVQLLMWFNLALIFPVLNLGPIYKDEMTDV
                     MTPFMCALLGLGLNEAAYMAEICRAGLLAVDEGQTEASHALGMSHAKTLRRIVIPQAMR
                     VIVPPTGNEFINMLKTSSLVYVVTYNELLRSTSVIGSSSFAVMELLFVASIWYLVMTSV
                     FSVFQYYLERYYARGSSRSLPPTVFQKIRANLLSIGRERSAS"
     gene            2032..2793
                     /locus_tag="IE189_RS09830"
                     /old_locus_tag="GCM10010496_19960"
     CDS             2032..2793
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973712.1"
                     /locus_tag="IE189_RS09830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_19960"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_189919847.1"
                     /transl_table=11
                     /translation="MTAMVKAEGVHKSFGAVEVLKGIDLEVKNGEVFCLIGPSGSGKST
                     FLRCINHLEKINAGRLYVDGDLVGYRQKGDKLYELKDSEVALKRRDIGMVFQRFNLFPH
                     MTALENVTEAPIQVKGVSKSQARERAAQLLERVGLADKAGNYPSQLSGGQQQRVAIARA
                     LAMDPKLMLFDEPTSALDPELVGDVLDVMRDLAESGMTMVVVTHEMGFAREVGDSLVFM
                     DGGVVVESGNPRDVLTDPQHERTKAFLSKVL"
     misc_feature    complement(2839..2853)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.41"
                     /tool="antismash"
     misc_feature    complement(3019..3034)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.99"
                     /tool="antismash"
     gene            3027..3656
                     /locus_tag="IE189_RS09835"
                     /old_locus_tag="GCM10010496_19970"
     CDS             3027..3656
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326935.1"
                     /locus_tag="IE189_RS09835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_19970"
                     /product="ABATE domain-containing protein"
                     /protein_id="WP_189919849.1"
                     /transl_table=11
                     /translation="MELAYYSDYAVRLVNSEEPVRGKDALTSVEAVRALFGGNRSAARR
                     ATEADVTRFRAVRARLRAVFEAADGGDETLAVDLLNSLLLEFPVSPQISGHDVRDDDGR
                     PLWHMHLADHPSNATAGYAAIAAMGLAFHLTEYGVDRLGLCEAGPCRNAYLDTSTNRSR
                     RYCSDRCATRANVAAYRARKRLEADRTAVTGLTADSAQRATASGER"
     gene            complement(3560..3994)
                     /gene="sodX"
                     /locus_tag="IE189_RS09840"
                     /old_locus_tag="GCM10010496_19980"
     CDS             complement(3560..3994)
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016485 - protein processing [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009190575.1"
                     /locus_tag="IE189_RS09840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_19980"
                     /product="nickel-type superoxide dismutase maturation
                     protease"
                     /protein_id="WP_189920519.1"
                     /transl_table=11
                     /translation="MPELSHETERARSAALFGPAEVNGPSMVPTLYHGDRLVVQYGARV
                     RPGDVVVLRHPFQQDLLVVKRATERREGGWWVRGDNTYAGGDSTDYGTVPDELVLGKVR
                     LRYRPRKPDQRSPLAVARWALSAVRPVTAVRSASRRLRAR"
     misc_feature    4076..4087
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.76"
                     /tool="antismash"
     gene            4140..4535
                     /gene="sodN"
                     /locus_tag="IE189_RS09845"
                     /old_locus_tag="GCM10010496_19990"
     CDS             4140..4535
                     /EC_number="1.15.1.1"
                     /GO_function="GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016151 - nickel cation binding [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313646.1"
                     /locus_tag="IE189_RS09845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_19990"
                     /product="superoxide dismutase, Ni"
                     /protein_id="WP_020130742.1"
                     /transl_table=11
                     /translation="MLSRLFAPKVKVSAHCDLPCGVYDPAQARIEAESVKAVQEKMAAN
                     DDPHFQARATVIKEQRAELAKHHVSVLWSDYFKPPHFEKYPQLHQLVNDTLKALSAAKA
                     STDPKTGEKALELIAEIDKIFWETKKA"
     gene            4696..5097
                     /locus_tag="IE189_RS09850"
                     /old_locus_tag="GCM10010496_20000"
     CDS             4696..5097
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010353600.1"
                     /locus_tag="IE189_RS09850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20000"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_189919851.1"
                     /transl_table=11
                     /translation="MTLEDLRRLRQARDRMDREYAEPLDVSALARTALMSPGHFQRSFR
                     EAYGETPYGYLMTRRVERAKTLLRRGDLTVTEVCMAVGCTSLGSFSSRFTELVGETPSA
                     YRARSHEDGAVVPACVARTYTRPRRDRRA"
     gene            5107..5520
                     /locus_tag="IE189_RS09855"
                     /old_locus_tag="GCM10010496_20010"
     CDS             5107..5520
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674926.1"
                     /locus_tag="IE189_RS09855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20010"
                     /product="VOC family protein"
                     /protein_id="WP_189919853.1"
                     /transl_table=11
                     /translation="MDLKLHQCFVAVDDHDKALHFYVEVLGLEVRNDVSFEGMRWVTVG
                     SPLQPDVNIVLEPPGANPDFSPADREAMARLLAKGVLRGVIFTTSDCDALHARVREAGC
                     DVLQEPTDQPYGVRDCAFRDPAGNMLRFMERPG"
     gene            5517..6296
                     /locus_tag="IE189_RS09860"
                     /old_locus_tag="GCM10010496_20020"
     CDS             5517..6296
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571365.1"
                     /locus_tag="IE189_RS09860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20020"
                     /product="VOC family protein"
                     /protein_id="WP_189919855.1"
                     /transl_table=11
                     /translation="MSRPVRWSYVFADRPAAHFGRACDFWTAVTGTALSQPRGDEGEFV
                     TLVPEGSDACVKAQAVTDGDGGAHLDLAVDDVPAFVAAALESGAGTAARHDGWAVLRSP
                     AGQLLCVVPWQGESERPPVVDGARVDQICMDVPPSAYATEVAFWSALLPDWPSRPGSRP
                     EFRVVEQPPGLPVRILLQRLETERAAGAHLDLTCGPDVGAVRARHEELGAVVVAGRPHW
                     TVMRDPAGGLYCLTGRDARTGGLPQPVAPPPEPATGR"
     gene            complement(6396..6977)
                     /locus_tag="IE189_RS09865"
                     /old_locus_tag="GCM10010496_20030"
     CDS             complement(6396..6977)
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020130746.1"
                     /locus_tag="IE189_RS09865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20030"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_189919857.1"
                     /transl_table=11
                     /translation="MSNSQVTLISPALSPALREARFDDGGGGLDAAGVRAARSAAARLP
                     LADRTAASPSARCRLTAEALGLSAPGAPALASLDVGRWRGLTLAEVTATEPDAVSAWLT
                     DPAAAPHGGETVRELCARAGAWLEETGRTPGRTIAVTEPDVVRALLVSGLGLPEPAFWR
                     LDVRPLTAVELSGRAGRWNLRMGTPLAADS"
     regulatory      7131..7223
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            7284..7505
                     /locus_tag="IE189_RS09870"
                     /old_locus_tag="GCM10010496_20040"
     CDS             7284..7505
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014045240.1"
                     /locus_tag="IE189_RS09870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20040"
                     /product="CbtB-domain containing protein"
                     /protein_id="WP_189919859.1"
                     /transl_table=11
                     /translation="MAQTVAQPTAGPAAVPAKLPIGAIVPWAVFFGILMMVLLYFVGAE
                     QGATSVVSGEDVHEWVHDARHLLGFPCH"
     gene            7523..8293
                     /locus_tag="IE189_RS09875"
                     /old_locus_tag="GCM10010496_20050"
     CDS             7523..8293
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009192299.1"
                     /locus_tag="IE189_RS09875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20050"
                     /product="CbtA family protein"
                     /protein_id="WP_189919861.1"
                     /transl_table=11
                     /translation="MNSAIVRNLLVRGMLAGLAAGLLALAVAYFLGEPRVDSAIAYEDS
                     HSHAHEHGVELVSRTMQSTGGLATGVLLYGVAFGGIAALAYCFALGRIGRFGPRASALL
                     LSGAGLLAVYVVPFLKYPANPPSVGDPDTIGRRTTLYFLMMVLSVLLAVGTVIVGKRLA
                     PRLGTWNATIAAGAFFVLTVGLAYAFLPAVNEVPKDFSGTLLWQFRLAALAIQLTLWTA
                     FGLVFGLLAERLLSPRPAGAGQRGASAQAAPAAH"
     gene            complement(8296..8514)
                     /locus_tag="IE189_RS38970"
                     /old_locus_tag="GCM10010496_20060"
     CDS             complement(8296..8514)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657883.1"
                     /locus_tag="IE189_RS38970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20060"
                     /product="hypothetical protein"
                     /protein_id="WP_229901171.1"
                     /transl_table=11
                     /translation="MDREQRVCPACGQPVQSVVRRHKTLGAWVPRWVAGPCHNTECEAY
                     TEPAPHHEMARAETEEEPGTPAAPASS"
     gene            complement(8562..9146)
                     /locus_tag="IE189_RS09880"
                     /old_locus_tag="GCM10010496_20070"
     CDS             complement(8562..9146)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973718.1"
                     /locus_tag="IE189_RS09880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20070"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_189919863.1"
                     /transl_table=11
                     /translation="MRKLTYYVACSVDGFIGDATGDGTAMLACLDEEFLDFLRTEYPET
                     VPTHSRRALGFDDLENRRFDTIVQGRASYDLALKEGIPSPYAHLRQYVASRTLAVSPSP
                     DVEIVADGLVDKVRELKAEDGGLGIYLCGGSRVAGELYDEIDELVIKTYPVVYGTGMPM
                     FAAGSDLTRFGLAGTRTFGNGAVVRTYARQR"
     gene            9269..9877
                     /locus_tag="IE189_RS09885"
                     /old_locus_tag="GCM10010496_20080"
     CDS             9269..9877
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020130749.1"
                     /locus_tag="IE189_RS09885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20080"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_189919865.1"
                     /transl_table=11
                     /translation="MAGNPERRAALVDAGVEVLAREGARGLTFRAVDAAAAVPVGTASN
                     YFTGRDDLLRQIDARLHVRLAPDPEVLGALMARPRDRALVTAFMHDLTARATRDRTGYL
                     ALLEMRLEATRRPELRASFTTSVRGDLQEGMDFHREAGLPGGDATVVVLYLAMLGMLLE
                     HLTLPDVLNDVLPGVTVPEGLVEQIVAMVVPDGPEAASK"
     gene            complement(10001..11059)
                     /locus_tag="IE189_RS09890"
                     /old_locus_tag="GCM10010496_20090"
     CDS             complement(10001..11059)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003998011.1"
                     /locus_tag="IE189_RS09890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20090"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_229901194.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.5e-61, bitscore:
                     203.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSQGDSGRVPVDTHEAAAILERSRASVDPELRAAIDLLPASMRR
                     VALYHFGWEHADGTAAAGNAGKAIRPALVLAAATALGGPAARAAALRAAAAVELVHNFT
                     LLHDDVMDRDTTRRHRPTAWTVFGDADAILAGDALQALALGLLAADPHPASAAAVARVA
                     ACVVELCAGQQADTAMERRGPADITLDEVLVMAEAKTGALLGCACAVGALYAGAAEEDV
                     EALDAFGRQAGLAFQLIDDVIGLWGDPLHTGKPAGADLAARKKSLPVVAALTSGTPAAG
                     ELAELYAAPYEPADLDRTLLAVERAGGREWAQEQAADRMARAMHELARAIPDPESAGGL
                     LCLAEFVTRRSN"
     gene            complement(11110..12516)
                     /locus_tag="IE189_RS09895"
                     /old_locus_tag="GCM10010496_20100"
     CDS             complement(11110..12516)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136651.1"
                     /locus_tag="IE189_RS09895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20100"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_189919869.1"
                     /transl_table=11
                     /translation="MSVGEEVRTDSGKPQQSLGTAAARNLATTTKSAPQMQEISSRWLL
                     RTLPWVDVQGGTYRVNRRLTYAVGDGRITFVKTGDRVEVIPAELGELPALRSYEDEEVL
                     GELAQRCRQREFAPGEVIASFGSSSEEVYLLAHGRVEKVGTGPYGDDQVLGVLADGAYF
                     GEAALLDADAIWEYTARADTACTVLVLARQDVEQVAERADTLRGHLQQLRAIPEQRTNK
                     YGEKEVDLAAGHAGEPDIPHTFVDYDARPREYELSIAQTVLRIHSRVADLYNQPMNQTE
                     QQLRLTVEALKERQEHELVNNREFGLLHNCEYDQRLQPHDGVPSPDDLDELLSRRRGTK
                     MLLAHPRAISAIGRELNKRGLVPESIDVGGNRIPTWRGVPIYPCNKIPVTEARTSSIIA
                     LRLGQEDQGVIGLRQSGIPDEIEPSLSVRFMGINEQAIIKYLVTAYYSAAVLVPDALGV
                     LENVEIGRWR"
     gene            12692..13576
                     /locus_tag="IE189_RS09900"
                     /old_locus_tag="GCM10010496_20110"
     CDS             12692..13576
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020130752.1"
                     /locus_tag="IE189_RS09900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20110"
                     /product="1-aminocyclopropane-1-carboxylate
                     deaminase/D-cysteine desulfhydrase"
                     /protein_id="WP_189919871.1"
                     /sec_met_domain="PALP (E-value: 5.8e-20, bitscore: 67.0,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDLRPRLPSPLREVSDDRFARHGVRLLLKRDDLIHPELIGNKWR
                     KLAPNLERAAGRTLLTFGGAYSNHLRATAAAGRLLGLPTVGVVRGDELAGRPLNPSLAR
                     CAADGMRLHFVDRPTYRRKTEADVLATLLERAGAPDAYVVPEGGSNAAAVRGCRALGEE
                     LRGRTDVVALACGTGGTLAGLAAGLAPGQLALGIPVLKGGFLGDAIAALQDEAFGGRRG
                     EWRLDERFHFGGYARVTPALEAFASDFERRHGVPVERLYVAKSLFGLAALAEEGAFPRG
                     TTVTAVITGRPFP"
     gene            complement(13652..15250)
                     /locus_tag="IE189_RS09905"
                     /old_locus_tag="GCM10010496_20120"
     CDS             complement(13652..15250)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019072182.1"
                     /locus_tag="IE189_RS09905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20120"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_189919873.1"
                     /transl_table=11
                     /translation="MDVMPLLLLVAGSAAFAAAARRTPVPAPLLLVAVGLVVSYVPGVP
                     DYTLDPDVVLPLLLPPLLYTSATDSSYLDLRAQLRPVALLSVGYVLFATFAVGWAAYLI
                     VPGLPLTAALVLGAVVAPPDAVAATAVARRVGLPSRITTILQGESLLNDATAITAYKVA
                     LAVVVGEGASWAGGIEEFLVAAVGGTAVGLVLMAPLHWLRTHLKEPLLQNTLSLLIPFV
                     AYAAAEQFHASGVIAVVVVALYLGHRAWEVDFATRLQEEAVWKMVAFVLESAVFALIGL
                     QLPVVLKGLGAYEGLDAAWYAVALFVVVVVARFLWVYPATFLPRLMSARIRAREENPTW
                     RGPIVIAWAGMRGVVSLAIAFSIPLTVDHGDAPFPYRNLILFLTFTTVIGTLVVQGLTL
                     PPLIRLLKFPEPDPQAATLAEANAQAQASRVAEERLDALLADERNALPPPLADRLRSVL
                     ERRRNAVWERLGQVNPVTGETVDDTYRRLSREMISAEREMFVRLRDGRYIDDEMLRTLL
                     RRLDLEEAAAYREAA"
     gene            15311..15571
                     /locus_tag="IE189_RS09910"
                     /old_locus_tag="GCM10010496_20130"
     CDS             15311..15571
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571357.1"
                     /locus_tag="IE189_RS09910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20130"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_189919875.1"
                     /transl_table=11
                     /translation="MKQCTHSDALPHPEPVPLGETCPECLRDGTHPVQLRLCLTCGHVG
                     CCDSSPSRHATAHHNESGHPVMRTFEPGENWRWCFVDHVLV"
     misc_feature    complement(15774..15787)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.16"
                     /tool="antismash"
     gene            15915..16328
                     /locus_tag="IE189_RS09915"
                     /old_locus_tag="GCM10010496_20140"
     CDS             15915..16328
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="IE189_RS09915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20140"
                     /product="anti-sigma regulatory factor"
                     /protein_id="WP_020130755.1"
                     /transl_table=11
                     /translation="MSQIAGEPATQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLSCVFRLVDDSLEVTVSAPTTDGHAPSRDTFAWTV
                     LSALAGKVSSAVDEDKTVTISLYKQRGAGPGPA"
     gene            16325..17437
                     /locus_tag="IE189_RS09920"
                     /old_locus_tag="GCM10010496_20150"
     CDS             16325..17437
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030133.1"
                     /locus_tag="IE189_RS09920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20150"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_189919877.1"
                     /transl_table=11
                     /translation="MRDGDGPVRDEERGTRELPADNAEIPVSPDGSRHMADGVDGIPEQ
                     ARPHPEDDASFVRAALPEGAAQGSPRERRIGGSPPGRAEARARQRATGGTMSEHERDGE
                     QSVPGARQEPPASPAPGDRSGARAMFVELRKLQDGSVEYAEMRNQLVRMHLPLVEHLAR
                     RFRNRGEPLDDLTQVATIGLIKSVDRFDPERGVEFSTYATPTVVGEIKRHFRDKGWAVR
                     VPRRLQELRLALTTATAELSQLHGRSPTVHELAEKLAISEEEVLEGLESANAYSTLSLD
                     VPDTDDESPAVADTLGAEDEALEGVEYRESLKPLLEDLPPREKRILLLRFFGNMTQSQI
                     AQEVGISQMHVSRLLARTLAQLREKLLVEE"
     gene            complement(17468..17908)
                     /locus_tag="IE189_RS09925"
                     /old_locus_tag="GCM10010496_20160"
     CDS             complement(17468..17908)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983568.1"
                     /locus_tag="IE189_RS09925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20160"
                     /product="hypothetical protein"
                     /protein_id="WP_189919879.1"
                     /transl_table=11
                     /translation="MSSDRTPDAPETPLSRPRRLTYAAALVALEGLALVVGGLWMLVLG
                     ISGDPDDRSQAVTGGVTLMVLALLPLLAARGLLGLRGWSRGPAVMTQIMVLPVAYNLLQ
                     ADSMAIPAGIALAAAAVASLVLLVNKETTRALGIRGPGRASE"
     gene            18057..19025
                     /locus_tag="IE189_RS09930"
                     /old_locus_tag="GCM10010496_20170"
     CDS             18057..19025
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127486.1"
                     /locus_tag="IE189_RS09930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20170"
                     /product="diacylglycerol kinase family protein"
                     /protein_id="WP_189919881.1"
                     /transl_table=11
                     /translation="MRALLVVNPAATTTSARTRDVLIHALASEMKLEAVTTEYRGHARD
                     LGRQAADSGNVDLVVALGGDGTVNEVVNGLLHAGPDPENLPGLAVVPGGSTNVFARALG
                     LPNDPVEATGALLDALRENTERTVGLGLAAGTPGTEDEAVPSRWFTFNAGLGFDAGVVG
                     RVEQQREHGRRSTHSLYIRQAVRQLLGESQRRHGSITLERPGADPVTDLVLSIVCNTAP
                     WTYLGNRPVYASPKASFDTGLDVLGLSRLSTASVARYGTQLLTSSPDRGPHGKHAVSLH
                     DLDRFTLHSKAPLPLQMDGDHLGLRTSVTFTGVRRALRVIV"
     misc_feature    complement(19115..19124)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.86"
                     /tool="antismash"
     misc_feature    complement(19227..19236)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.27"
                     /tool="antismash"
     misc_feature    complement(19286..19301)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     misc_feature    19289..19300
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     gene            19345..19602
                     /locus_tag="IE189_RS09935"
                     /old_locus_tag="GCM10010496_20180"
     CDS             19345..19602
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563321.1"
                     /locus_tag="IE189_RS09935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_20180"
                     /product="WhiB family transcriptional regulator"
                     /protein_id="WP_006380970.1"
                     /transl_table=11
                     /translation="MDWRHNAVCREEDPELFFPIGNTGPALLQIEEAKAVCRRCPVMEQ
                     CLQWALESGQDSGVWGGLSEDERRAMKRRAARNRARQATA"
     misc_feature    complement(20728..20742)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
ORIGIN
        1 tcgacccatc ggcatgtgcc gacccatcgg catctccatc catccgccgg aggaacccac
       61 catgaccgca agctccaccc gacgcacgac cgccgcgcgc acccgcctgg cagcggtcgg
      121 atctctcgcg gtcgcgggcg ccttgctgct ctccgcctgc ggcgaccaga ccgacagcgg
      181 cggcagctcc tccgagtcgt cgagcggcgc cgacaaggcc cctctcttct cgaagctccc
      241 ggccgacatc cagaaggcgg gtgtcatcaa ggtcggcacc aacgccgagt acgcgccgat
      301 ggagtccgtc gagggcggca agatcgtggg cgtcgacccc gacatcgccg ccgcgctcgg
      361 caaggaactc ggcgtcgact tccagttcac ctccggcggc ttcgacaccc tgatcacggc
      421 ggtcaacacc ggccgctacg acatcgcgat gtcgtcgatc acggacaaca agcagcgcca
      481 ggagggcctg gacgacagcg gcaagaagct cggcacgggc gtcgacttcg tcgactactt
      541 caccgccggc accgccatct acgtccagaa gggcaacccc aagggcatca agaccatcga
      601 cgacctgtgc ggtcagacgg tcgccgtgca gcggggcacc acctacgaag aggccctcca
      661 ggcgcagtcc aagacctgca ccggcagcgg caagaaggcc ctcaagatcg agtccttcga
      721 gaacgacacc gaggcccaga cccgcgtgaa gtcgggcggc gccgtggccg gcgtcaacga
      781 ctacccggtg gccgtggaca tggcccgcaa ggccggcggc ggcaacacct tcgaggttct
      841 cgacaagcag tacgaggccg ctccgttcgg catcgtcgtg aacaagaaga acacgcagct
      901 gcgcgacgcc ctcaaggagg ccgtcgacgc gatcatcaag gacggctcgt accagaaggt
      961 gctggagaag tggggcgccg agagcggggc gatcaaggcc tccgccatca acggcggcaa
     1021 gtgatccacc cgcacctttt gcagtcttcg aagggcagtc cccatgactg acaagctcga
     1081 caagtcctcc gcgggcggcg caccacccga ggacaccccg ccggtcgcca agggcccggc
     1141 gttctccggt ccgccggaga ccatcaaggc gatcccggtg cgccactacg gccgctgggt
     1201 cagcgcggtg atcgtcgtcg cgctgatggt gctgctggtc aacgccttcg ccaacggcga
     1261 catccagtgg agcacggtcg gcgaccagct gttcaactcg accgtcatcg cgggcgccgg
     1321 acgcaccctg ctgatcagcg tgctgtccat ggtgctgggc gtggtgctcg gtgttctgct
     1381 ggccgtcatg cggctgtcga agaacccggt gaccagcacg gtcgcctggc tgtacatctg
     1441 gttcttccgc ggcaccccgg tgtacgtgca gctgctgatg tggttcaacc tggcgctgat
     1501 cttccccgtc ctgaacctcg gtccgatcta caaggacgag atgacggacg tcatgacgcc
     1561 gttcatgtgc gccctgctgg gactcggcct gaacgaggcc gcgtacatgg ccgagatctg
     1621 ccgggccggc ctgctggccg tggacgaggg gcagacggag gcgtcgcacg cgctgggcat
     1681 gagccacgcc aagacgctgc gccggatcgt catcccgcag gcgatgcggg tgatcgtgcc
     1741 gccgaccggc aacgagttca tcaacatgct gaagacctcg tcgctggtgt acgtggtgac
     1801 gtacaacgaa ctgctccgct cgacctcggt gatcggctcc tcgtcgttcg ccgtgatgga
     1861 gctgctgttc gtcgcctcca tctggtacct ggtcatgacc agcgtcttca gcgtcttcca
     1921 gtactacctg gagcgctact acgcccgcgg ttcgagccgc agcctgccgc ccacggtctt
     1981 ccagaagatc cgggcgaacc tgctctcgat cggccgcgaa aggagtgcgt catgaccgcg
     2041 atggtcaagg ccgagggtgt gcacaagtcc ttcggcgcgg tcgaggtcct caagggcatc
     2101 gacctggagg tcaagaacgg cgaggtgttc tgcctcatcg gcccctccgg ttccggcaag
     2161 agcacgttcc tcaggtgcat caaccacctg gagaagatca acgccggacg gctgtacgtc
     2221 gacggggacc tggtcggcta ccgccagaag ggcgacaagc tctacgagct gaaggacagc
     2281 gaggtcgcgc tgaagcgccg ggacatcggc atggtgttcc agcggttcaa cctgttcccg
     2341 cacatgacgg cgctggagaa cgtcaccgag gctccgatcc aggtcaaggg cgtgagcaag
     2401 tcccaggcca gggagcgcgc ggcccagctc ctggagcgcg tgggcctcgc cgacaaggcg
     2461 gggaactacc cctcgcagct ctccggcggt cagcagcagc gggtggcgat cgcccgggcc
     2521 ctggccatgg acccgaagct gatgctgttc gacgagccga cctcggcact cgacccggag
     2581 ctggtcggcg acgtcctcga cgtcatgcgc gacctggccg agtccggcat gacgatggtc
     2641 gtcgtcaccc acgagatggg cttcgcccgc gaggtcggcg acagcctggt cttcatggac
     2701 ggcggtgtgg tggtcgagtc cggcaacccg cgtgacgtcc tgaccgaccc gcagcacgag
     2761 cggacgaagg cgttcctgtc caaggtgctg tgacgcgtac ggcggtgccg tgacgcgtac
     2821 ggtacgacgg cgaaggggcg gtacggatct tccgtaccgc cccttcggcc gtgccgccgg
     2881 ggtgcgggac gggcgaaggg gcgtcacccc ggccgcgcgt ccgtcggggt gacgtcgtcc
     2941 gggtgtgtcc cgtaataccc tggaggcacg aacggccgtt accccgcccg cacccggacc
     3001 gcagagcgcc accgtaagga ctacaagtgg aactggccta ttactcggat tatgccgtgc
     3061 gcctcgtcaa cagcgaggaa ccggtccggg gcaaggacgc gctgacctcg gtcgaggcgg
     3121 tccgcgccct cttcggcggc aaccggtcgg cggcccgccg cgccaccgag gcggacgtca
     3181 cccggttccg tgcggtccgg gcccggctgc gcgcggtgtt cgaggcggcc gacggcggtg
     3241 acgagaccct cgccgtggac ctgctgaact cgctgctgct ggagttcccg gtgagcccgc
     3301 agatctccgg ccacgacgtc cgcgacgacg acggccgccc gctgtggcac atgcacctgg
     3361 ccgaccaccc gtcgaacgcg acggccggct acgcggccat cgcggccatg ggcctggcgt
     3421 tccacctcac cgagtacggc gtcgaccgcc tggggctgtg cgaggcgggc ccctgccgca
     3481 acgcctacct cgacacgtcg accaaccgct cccggcgcta ctgctccgac cgctgcgcca
     3541 cccgcgcgaa cgtggccgcc taccgggccc gcaagcgcct ggaggccgac cgcacggccg
     3601 tcaccggtct gaccgcggac agcgcccagc gcgccacggc cagcggcgag cgctgatccg
     3661 gcttgcgcgg gcggtagcgc agccgcacct tgccgaggac cagctcgtcg ggcacggtcc
     3721 cgtagtcggt gctgtcgccg ccggcgtagg tgttgtcccc gcggacccac catccgccct
     3781 cgcggcgctc cgtggcccgc ttgaccacga gcaggtcctg ctggaagggg tgccgcagca
     3841 cgacgacgtc tccgggccgg acccgggcac cgtactgcac caccagccgg tccccgtggt
     3901 agagcgtggg caccatggac gggccgttca cctcggccgg tccgaagagc gcggccgatc
     3961 tcgcgcgctc ggtctcgtgc gacagctccg gcatcgccgg cacctccccg gtccgatcct
     4021 ccaccagtcc cagtctgacc ccggactttt gtcctaagcc cacgggggca cccgcgaaaa
     4081 ggcttccctc agggagtaat gtcccacctg agaagacgat cacgaggaag gaacgctcca
     4141 tgctttcccg cctgtttgcc cccaaggtca aggtcagcgc tcactgcgac ctgccctgcg
     4201 gtgtgtacga cccggcccag gcccgcatcg aggcggagtc ggtgaaggcc gtccaggaga
     4261 agatggccgc caacgacgac ccgcacttcc aggcgcgcgc caccgtcatc aaggagcagc
     4321 gtgccgagct ggcgaagcac cacgtctccg tgctgtggag cgactacttc aagcccccgc
     4381 acttcgagaa gtacccccag ctgcaccagc tggtcaacga caccctgaag gccctgtcgg
     4441 ccgccaaggc ctcgacggac ccgaagaccg gcgagaaggc cctggagctc atcgccgaga
     4501 tcgacaagat cttctgggag accaagaagg cctgatcccc cgatcgagcc gtgcggcccg
     4561 cgaccgcccg gtcgcccggt ccgcctgtcc gcacccggcc cgcaggacgc ccgtcacggc
     4621 gctcctgacg gtccgggtgc ggtctccttt cccgcccggc gccctcgtgg gcgccccgcg
     4681 tgcgatgctg gccccgtgac cctcgaggac ctgagacggc tgcggcaggc acgcgaccgg
     4741 atggaccgtg agtacgccga gccgctcgac gtctccgcgc tcgcgcgcac cgcgctgatg
     4801 tccccgggcc acttccagcg cagcttccgc gaggcgtacg gcgagacgcc ctacggctac
     4861 ctgatgaccc gcagggtgga gcgggccaag accctcctgc gccgcggcga cctcacggtg
     4921 accgaggtct gcatggcggt cggctgcacc tcgctcggct cgttcagctc gcgtttcacc
     4981 gagctggtcg gcgagacgcc gagcgcctac cgggcgcggt cgcacgagga cggcgcggtg
     5041 gtcccggcgt gcgtcgcccg cacgtacacc cgcccgcggc gggaccggcg cgcctaggct
     5101 gggcgcatgg acctcaaact ccaccagtgt ttcgtcgccg tcgacgacca cgacaaggcc
     5161 ctgcacttct acgtcgaggt gctcggcctc gaagtccgca acgacgtctc cttcgagggg
     5221 atgcggtggg tgaccgtcgg gtcgccgctc cagccggacg tgaacatcgt gctggagccg
     5281 ccgggcgcga acccggactt ctcgccggcc gaccgggagg cgatggcccg gctgctcgcc
     5341 aagggcgtgc tgcgcggggt catcttcacc acctccgact gcgacgcgct gcacgcgcgc
     5401 gtgcgggagg ccggctgcga tgtgctccag gagccgaccg accagccgta cggggtgcgc
     5461 gactgcgcct tccgtgaccc ggccgggaac atgctgcggt tcatggagcg gcccggatga
     5521 gccgaccggt ccgctggtcc tacgtcttcg ccgaccggcc cgccgcgcac ttcgggcggg
     5581 cctgcgactt ctggaccgct gtcacgggga cggccctgtc gcaacccagg ggcgacgagg
     5641 gcgagttcgt caccctggtg ccggagggat ccgacgcgtg cgtgaaggcc caggcggtca
     5701 cggacgggga cggcggcgcg catctcgacc tcgccgtcga cgacgtgccg gcgttcgtgg
     5761 ccgccgcgct ggagtcgggg gcgggcacgg ccgcccggca cgacggctgg gccgtactgc
     5821 gctcacccgc cgggcagttg ctctgtgtgg tgccctggca gggggagtcc gagcggccgc
     5881 ccgtggtgga cggcgcccgc gtggaccaga tctgcatgga cgtcccgccg tcggcgtacg
     5941 cgaccgaagt cgccttctgg agcgccctgt tgcccgactg gccgtcccgg ccgggatcac
     6001 ggcccgagtt ccgtgtcgtc gagcagccgc cggggctccc ggtgcgcatc ctgctccagc
     6061 ggctcgaaac ggaacgcgcc gcgggcgccc acctcgacct gacctgtggc ccggacgtcg
     6121 gcgccgtccg cgcacggcac gaggagctcg gcgcggtcgt cgtggccggc cgtccccact
     6181 ggacggtgat gcgcgacccg gccggcgggc tctactgcct gaccgggcgc gacgcgcgga
     6241 cgggcggact gccgcaaccc gtcgcccctc ccccggaacc cgccacgggc cgctgaccgg
     6301 gcacggccgc aaggccgccg cccccgggct cccgcccccg gcccatgagc cttccggccc
     6361 ttgcgtcctc cggccaggaa tccgtcagta gtccgctagg agtccgctgc gagcggtgtt
     6421 cccatccgga ggttccaccg tcccgcccgg ccgctcagtt ccaccgcggt cagcgggcgt
     6481 acgtccaggc gccagaaggc cggttccggc aggccgagcc cgctcaccag gagggctcgc
     6541 acgacgtcgg gttccgtcac cgcgatcgtc cggcccgggg tgcggccggt ctcctccagc
     6601 caggccccgg cccgggcgca cagctcgcgc accgtctccc cgccgtgcgg ggccgctgcc
     6661 gggtccgtca gccaggcgga caccgcgtcc ggctcggtgg ccgtcacctc ggcgagggtg
     6721 agaccccgcc agcggcccac gtcgagggag gcgagcgcgg gcgccccggg cgcggacagg
     6781 cccagcgcct cggcggtcag ccggcaccgc gcggaggggg aggcggccgt gcggtccgcg
     6841 agcggcagcc gggccgcggc cgaccgcgcc gcgcgcaccc cggcggcgtc cagcccaccg
     6901 ccgccgtcgt cgaaccgcgc ctcgcgcaga gcgggcgaga gtgccggtga gatcaaggtc
     6961 acctgactgt tcgacaatct cccaagccct tctttcgctt ctcaactcac ctgcacagca
     7021 aggacgttga ggcgtgatcg ccggtccttg cgcttctgcg ccgccccatg cgcccttggc
     7081 cgcgcagccg ccacgcggta cgttctgcgc gacattgacg acggtacggc ggaagtccgg
     7141 tgggaatccg gcacggtcgc gccactgtaa gccgacggaa gcctccccct cacgggtggt
     7201 ggcggacgcc gagcaagtca gacccgcacc cgtcgtcacg tgcaccaccg agatgggacg
     7261 cgaactcccg aggaggtcct gccatggcgc agaccgtcgc ccagccgacc gccggccccg
     7321 ccgccgtacc cgccaagctg ccgatcgggg cgatcgtccc ctgggcggtc ttcttcggca
     7381 tcctgatgat ggtcctgctg tacttcgtcg gcgccgagca gggcgccacc tccgtggtct
     7441 ccggcgagga cgtccacgag tgggtgcacg acgcccgcca cctgctcggc ttcccctgcc
     7501 actgacgggg gaaccggaca ccgtgaactc cgcaatcgtc aggaacctcc tggtccgcgg
     7561 catgctcgcc ggcctcgccg ccggactgct cgccctcgcc gtggcctact tcctgggcga
     7621 accgcgcgtc gattcggcga tcgcctacga ggattcccac tcccacgccc atgagcacgg
     7681 cgtggaactc gtctcccgca cgatgcagtc caccggcggc ctggccaccg gcgtgctgct
     7741 ctacggcgtc gcgttcggcg gcatcgccgc cctcgcctac tgcttcgcgc tcggccggat
     7801 cggccggttc ggcccccggg cgagcgcgct gctcctgtcg ggcgcgggcc tgctcgccgt
     7861 ctacgtggtg ccgttcctga agtacccggc caacccgccc tccgtcggtg accccgacac
     7921 catcggcagg cggaccaccc tgtacttcct gatgatggtg ctcagtgtgc tcctggccgt
     7981 cggcacggtc attgtgggca agcggctcgc accccgcctg ggcacgtgga acgcgacgat
     8041 cgccgcgggg gcgttcttcg tcctcacggt cggcctcgcc tacgcgttcc tgccggccgt
     8101 caacgaggtc cccaaggact tctccggcac gctgctctgg cagttccggc tggccgccct
     8161 cgccatccag ctcaccctgt ggacggcctt cgggctcgtc ttcgggctgc tggcggagcg
     8221 gctgctgtca ccccgcccgg ccggcgccgg acagcggggc gcctccgcgc aggcggctcc
     8281 cgcggcgcac tgaggtcagg aggaggccgg ggccgcgggg gtcccgggtt cctcttccgt
     8341 ctcggcccgg gccatctcgt ggtgcggggc cggctcggtg tacgcctcgc actccgtgtt
     8401 gtgacaaggg cccgccaccc agcgcgggac ccacgcgccg agcgtcttgt gacgccggac
     8461 gacggactgc acaggctgcc cgcaagcggg acagacgcgt tgttcccggt ccatgcccta
     8521 cagactagga cggccggggc gagagcgctc cccgcggtac gtcaccgctg ccgggcgtac
     8581 gtgcgcacga ccgcgccgtt gccgaaggtg cgcgtcccgg cgaggccgaa ccgggtgagg
     8641 tcggagccgg cggcgaacat cggcatgccg gtgccgtaga cgaccgggta ggtcttgatc
     8701 acgagctcgt cgatctcgtc gtacagctcg cccgcgacgc gggagccgcc gcacaggtag
     8761 atccccaggc cgccgtcctc ggccttcagc tcgcggacct tgtcgaccag gccgtccgcg
     8821 acgatctcga cgtccgggga cggcgacacc gcgagggtgc gcgaggcgac gtactggcgc
     8881 agatgcgcgt aggggctcgg gatgccctcc ttcagcgcca ggtcgtagct ggcgcggccc
     8941 tggacgatcg tgtcgaaccg cctgttctcc aggtcgtcga agccgagggc gcggcggctg
     9001 tgggtgggca cggtctccgg atactcggtc cggaggaagt cgaggaactc ctcgtccaga
     9061 caggcgagca tcgccgtgcc gtcaccggtc gcgtccccga tgaagccgtc gacggagcac
     9121 gcgacgtagt acgtgagctt tcgcaagtgg gtctctttcc gtaggctgcc ttccgaacca
     9181 cttcagttgt agtacttcac ttgtagtggt tgcaagagga ttctcccgcg acgcgggaaa
     9241 cggggccaag tgagagagag ggttccgcat ggccggaaat ccggagcgcc gggcggccct
     9301 ggtggacgcc ggggtcgagg tgctcgcacg ggagggcgcg cgcgggctga cgttccgcgc
     9361 ggtggacgcg gcggcggcgg tcccggtggg caccgcctcg aactacttca ccgggcgcga
     9421 cgacctgctg cggcagatcg acgcccggct gcacgtccgg ctggcgcccg accccgaggt
     9481 gctcggcgcg ctgatggcca ggccccggga ccgcgccctg gtcacggcgt tcatgcacga
     9541 cctgacggcc cgcgcgaccc gcgaccggac gggctacctg gccctgctgg agatgcgcct
     9601 cgaagcgacc cggcgccccg aactgcgcgc ctccttcacc acctccgtgc gcggcgatct
     9661 ccaggagggc atggacttcc accgcgaggc ggggctgccc ggcggcgacg cgaccgtggt
     9721 cgtcctctac ctggcgatgc tgggcatgct cctggaacac ctcaccctgc cggacgtcct
     9781 gaacgacgtc ctgcccgggg tgacggtccc agaaggcttg gtcgaacaga tcgtggccat
     9841 ggtggtgccg gacggcccgg aggcggcctc caagtagaac gcgcgcctcg ggcgcgggag
     9901 ccggagggca gccccggggc cggagccgag tccgcccccg gggccgaagc cggccgcggg
     9961 ggcggatcgc ggctgtccgg gtgccggagc cgcggagcgc tcagttgctg cggcgggtca
    10021 cgaactcggc gagacagagc aggccgccgg ccgattccgg gtcggggatc gcccgggcca
    10081 gttcgtgcat cgcccgggcc atccggtcgg ccgcctgctc ctgcgcccac tcgcggccgc
    10141 cggcccgttc gacggccagc agcgtgcggt ccaggtcggc cggctcgtac ggcgccgcgt
    10201 acagctcggc cagctcaccc gccgccgggg tgccggaggt cagcgcggcg accaccggca
    10261 gggacttctt gcgggcggcg agatccgctc cggccggctt gccggtgtgc agcgggtctc
    10321 cccacagccc gatgacgtcg tcgatgagct ggaaggcgag cccggcctgt ctgccgaacg
    10381 cgtccagcgc ctccacgtcc tcctcggccg ctcccgcgta cagcgcgccc accgcacagg
    10441 cgcaacccag cagcgctccc gtcttggcct cggccatgac gagcacctcg tcgagggtga
    10501 tgtccgcggg gccgcgtctc tccatcgccg tgtccgcctg ctggccggcg cagagctcga
    10561 ccacacaggc cgcgacccgt gcgacggccg ccgcggacgc gggatgcggg tcggcggcca
    10621 gcagtcccag ggcgagggcc tggagggcgt ccccggcgag aatcgcgtcg gcgtcgccga
    10681 acacggtcca ggcggtgggg cggtgccggc gcgtggtgtc ccggtccatc acgtcgtcgt
    10741 gcagcaacgt gaagttgtgg accagttcga ccgcggcggc cgcccgcagg gccgccgccc
    10801 gggccgccgg gccaccgagg gcggtggccg cggcgagcac cagggcgggg cggatcgcct
    10861 tgcccgcgtt gcccgccgcc gcggtgccgt ccgcgtgctc ccagccgaag tggtagagcg
    10921 cgacccggcg catcgaggcg ggcagcagat cgatcgcggc gcgcagttcg gggtcgaccg
    10981 acgcccggga gcgctccagg atcgccgccg cctcgtgcgt gtccaccggt acccgaccgc
    11041 tgtcgccctg gctgccgatg gacccccgcc tttcgcgtgc cccgctgcgc tgatcccgga
    11101 cggcggacgt caccgccagc ggccgatctc gacgttctcc aggacgccca gcgcgtccgg
    11161 caccaggacg gcggccgagt agtacgccgt gaccaggtat ttgatgatgg cctgttcgtt
    11221 gatgcccatg aaccgcacgg acaggctcgg ctcgatctcg tccgggatgc cggactggcg
    11281 caggccgatg acgccctggt cctcctggcc cagacgcagc gcgatgatcg agctggtgcg
    11341 ggcctcggtg accgggatct tgttgcacgg gtagatcggc accccgcgcc aggtcgggat
    11401 ccggttgccg ccgacgtcga tgctctcggg gaccagcccg cgcttgttga gctcgcggcc
    11461 gatcgcggag atcgcgcgcg ggtgggcgag cagcatcttg gtgccgcggc gcctgctgag
    11521 cagttcgtcc aggtcgtccg ggctcggcac gccgtcgtgc ggctggagcc gctggtcgta
    11581 ctcgcagttg tgcagcagtc cgaactcgcg gttgttgacc agctcgtgct cctggcgctc
    11641 cttgagcgcc tcgaccgtca gccgcagctg ctgctcggtc tggttcatcg gctggttgta
    11701 gaggtcggcc acgcgcgagt ggatgcgcag cacggtctgg gcgatgctca gttcgtactc
    11761 gcgcggccgg gcgtcgtagt ccacgaacgt gtgcgggatg tccggctcgc cggcgtggcc
    11821 cgcggcgagg tcgacctcct tctcgccgta cttgttggtg cgctgctccg ggatcgcgcg
    11881 cagctgctgg aggtgtccgc gcagggtgtc ggcgcgttcc gcgacctgtt cgacgtcctg
    11941 ccgggccagg accagcaccg tgcaggccgt gtccgcgcgg gccgtgtact cccagatggc
    12001 gtcggcgtcg agcagggccg cctcaccgaa gtaggcgccg tcggcgagga cgccgagcac
    12061 ctggtcgtcg ccgtaggggc cggtgccgac cttctccacg cggccgtgcg ccaggaggta
    12121 gacctcctcg gacgagctgc cgaaggaggc gatcacctcg cccggggcga actcgcgctg
    12181 ccggcagcgc tgggcgagtt cgccgagcac ctcctcgtcc tcgtaggagc gcagtgcggg
    12241 cagttcgccc agctccgccg ggatgacctc gacccggtcg ccggtcttga cgaacgtgat
    12301 gcggccgtcg cccaccgcgt acgtcagacg cctgttgacc cggtacgtgc cgccctgcac
    12361 atccacccag ggcagggtcc gcagcagcca gcgggagctg atctcctgca tctgcggcgc
    12421 ggacttggtc gtggtggcca ggttccgcgc ggccgcggtg ccgagactct gctgcggctt
    12481 gcccgaatcc gtgcggacct cttcgcctac cgacatgaga aatgccctcc cgatccgtgc
    12541 accgggcgcc gaactgcgcc ggtgcacttc gttcacgcgg caagccttcc atcacggtgt
    12601 gtgctcgtgc tattacccga aagagcggga atggatcaac cgggcgctgg gaacaggcac
    12661 gattccccga acggtgttcg acaatgggcg ggtgaccgac ctgcgccccc gcctgccgtc
    12721 cccgctgcgg gaagtgtccg acgaccggtt cgcacggcac ggggtacggc tgctgctgaa
    12781 gcgggacgac ctgatccatc cggagctgat cggcaacaag tggcgcaagc tcgcgcccaa
    12841 tctggaacgg gcggcggggc ggacgctgct caccttcggc ggcgcctact ccaaccacct
    12901 gcgggccacg gccgccgccg gccggctcct gggcctgccc acggtggggg tggtgcgcgg
    12961 ggacgagctg gccgggcggc cgctgaaccc ctccctggcc cggtgcgcgg ccgacggcat
    13021 gcgcctgcac ttcgtggacc gcccgaccta ccgccgcaag acggaggcgg acgtgctcgc
    13081 gacgctcctg gagcgggccg gcgcaccgga cgcgtacgtc gtcccggagg gcggcagcaa
    13141 cgcggcggcg gtccgcggct gccgggcgct cggggaggag ctgcgcggcc gtaccgacgt
    13201 cgtcgcgctc gcctgcggca ccggcggcac tctcgcgggg ctggccgccg ggctcgcccc
    13261 cggccagctg gccctgggca taccggtcct caagggcggt ttcctggggg acgccatagc
    13321 ggcgctccag gacgaggcct tcggcggccg gcggggcgag tggcggctcg acgagcgctt
    13381 ccacttcggc ggctacgccc gggtcacccc cgccctggag gccttcgcgt cggatttcga
    13441 gcgacgccac ggcgtgcccg tcgaacgtct ctatgtcgcc aagtcgctct tcggccttgc
    13501 ggccctcgcc gaggaggggg ccttcccgcg cgggacgacg gtgacggccg tgatcaccgg
    13561 ccgcccgttc ccgtgacgcc gggcacgggg ggggcacggc ggcacccgcc cgtccccggc
    13621 ggccacgcac gcgtgccggc ccgcggcggg cctacgccgc ctcccggtag gccgccgcct
    13681 cctccaggtc cagtcggcgc agcagcgtgc gcagcatctc gtcgtcgatg tagcggccgt
    13741 cccgcagtcg gacgaacatc tcgcgctcgg cgctgatcat ctcgcgtgag agacggcggt
    13801 aggtgtcgtc gacggtctca ccggtgaccg ggttgacctg cccgaggcgc tcccagacgg
    13861 cgttgcggcg gcgctccagg acgctgcgca ggcggtcggc gagcggcggc ggcagggcgt
    13921 tgcgttcgtc ggccagcagc gcgtccagac gctcctcggc gacccgggag gcctgcgcct
    13981 gcgcgttggc ctcggcgagc gtcgccgcct gcggatcggg ctcggggaac ttcaggaggc
    14041 ggatcagcgg cggcagggtc agcccctgga cgaccagggt gccgatgacg gtggtgaagg
    14101 tgaggaagag gatgaggttg cggtagggga agggcgcgtc gccgtggtcc acggtgagcg
    14161 ggatcgagaa ggcgatggcg agcgagacca cgccccgcat cccggcccag gcgatgacga
    14221 tcggcccccg ccaggtgggg ttctcctccc gcgcgcggat acgcgccgac atcagccggg
    14281 gcaggaaggt cgcgggatac acccacagga agcgggccac cacgaccacg acgaagaggg
    14341 cgacggcgta ccaggcggcg tccaggccct cgtaggcgcc gaggcccttc aggacgacgg
    14401 ggagctggag gccgatcagc gcgaacaccg cggactccag gacgaaggcg accatcttcc
    14461 acacggcctc ctcctggagg cgggtcgcga agtccacctc ccacgcgcgg tggccgaggt
    14521 agagcgcgac gacgaccacg gcgatgacac cggaggcgtg gaactgctcg gcggccgcgt
    14581 acgccacgaa cgggatcagc agggacagcg tgttctggag gaggggctcc ttgagatggg
    14641 tgcgcagcca gtgcagcggc gccatcagga cgaggcccac ggcggtcccg ccgaccgccg
    14701 cgacgaggaa ctcctcgatg ccgccggccc aggaggcgcc ctcgccgacg acgaccgcga
    14761 gggccacctt gtaggcggtg atcgcggtgg cgtcgttcag cagcgactcg ccctggagga
    14821 tcgtggtgat ccgcgagggc agcccgaccc ggcgtgccac ggccgtcgcc gcgacggcgt
    14881 ccggcggcgc cacgaccgcg ccgaggacca gcgccgccgt cagcggcagc ccgggcacga
    14941 tcaggtaggc ggcccagccg acggcgaagg tcgcgaagag cacgtacccg accgagagca
    15001 gcgccaccgg ccgcagctgg gcgcgcaggt cgaggtacga gctgtcggtg gccgacgtgt
    15061 acagcagcgg gggcagcagc agcggcagca cgacgtccgg gtccagggtg tagtccggaa
    15121 cccccggtac gtaggacacc accaggccga ccgccaccag cagcagcggc gccggcaccg
    15181 gtgtgcgccg tgcagccgcc gcgaacgccg cgctgccggc caccagcaac agcagtggca
    15241 tcacgtccat gtctcgcccg ccctcgtttt tccgcgcggt cctccgcacg cccgtcgtaa
    15301 tctggcaatc atgaaacagt gcacgcactc cgacgcgctg ccccaccccg aacccgtccc
    15361 tctcggtgag acgtgtccgg agtgtctgcg ggacggcacc cacccggtgc agctccggct
    15421 ctgcctgacc tgtggccatg tcggctgctg cgactcctcg ccgagccggc acgcgaccgc
    15481 gcaccacaac gagtccggcc acccggtgat gcggaccttc gaacccggcg agaactggcg
    15541 gtggtgtttc gtggaccacg tcctcgtatg aggagaccat gtcacgtacg gccggtcccc
    15601 gtccggtccc gccgcccgtg aaccatcggg gcggggcgac cgttgaactc atgagacgtc
    15661 ccggccgtcc ggcgggtacg gttcgaccgt ctgacgtctg ggtacgtcaa cccggcgcgc
    15721 cctcttccca tttgggccga cggaccctct agacacggag cgtgttcaca gctttactgt
    15781 gagtgacgtc agggggttgg ggtcccgggg acagaaacct gggagcgcga tagcgtcacc
    15841 gctgcaccac acacggcgtt accccggggg gcgaccctcg gctccgaaca gcttgtacca
    15901 ccttggaggt gagggtgtcc cagatcgcag gcgagcccgc gacccaggac ttcgtggaag
    15961 tccggctgcc ggctgcgggt gcctacctgt cggtgctgcg gacggccacg gccggtctcg
    16021 cggcccgttt ggacttcacc ctggacgaga tcgaggacct ccgcatcgcg gtggacgagg
    16081 cctgcgcgat cctgctccag caggccgtgc ccggctcggt gctcagttgc gtcttccggc
    16141 tcgtcgacga ctcgctcgaa gtgaccgtct ccgcgccgac cacggacgga cacgccccct
    16201 cgcgggacac cttcgcctgg accgtcctgt ccgccctcgc gggcaaggtg tcctccgccg
    16261 tcgacgagga caagaccgtg acgatcagcc tctacaaaca gcgcggcgcg ggacccgggc
    16321 cggcgtgagg gacggggacg ggccggtgcg ggacgaagag cgcggcacac gggagctgcc
    16381 ggccgacaac gccgagattc ccgtctctcc ggacggttcc cgacacatgg cggacggggt
    16441 cgacggcatt cccgagcagg cccggccgca tccggaggac gacgcgtcct tcgtgcgggc
    16501 ggctctgccg gagggtgccg cgcagggctc gccccgggag aggcggatcg ggggctcgcc
    16561 cccgggccga gcagaggcga gggctcgaca gagggcgacg ggcgggacaa tgagcgagca
    16621 cgagcgagac ggcgaacaga gcgtgccggg cgcacggcag gaaccaccgg catcccccgc
    16681 gccgggggac cgcagcggag cacgggctat gttcgtcgag ctgcgcaagc tccaggacgg
    16741 cagcgtcgag tacgcggaga tgcgcaacca gctggtccgg atgcatctgc cgctcgtcga
    16801 gcacctcgcg cggcgcttcc gcaaccgcgg cgagccgctg gacgacctca cccaggtcgc
    16861 caccatcggc ctgatcaagt cggtcgaccg cttcgatccg gagcgtggcg tggagttctc
    16921 cacgtacgcg acgccgacgg tcgtcggcga gatcaagcgg cacttccgtg acaagggctg
    16981 ggcggtacgg gtgccgcgca ggctccagga gctgcgcttg gccctgacca cggcgacggc
    17041 cgagctgtcg cagctgcacg gccgctcccc cacggtccac gagctcgccg agaaactggc
    17101 gatctcggag gaggaggtcc tggagggcct ggagtccgcc aacgcgtact ccaccctctc
    17161 gctggacgtg cccgacaccg acgacgagtc gccggcggtc gcggacaccc tgggcgcgga
    17221 ggacgaggcg ctggagggcg tcgagtaccg ggagtccctc aagccgctcc tggaggacct
    17281 cccgccgcgc gagaagcgga tcctgctgct gcggttcttc ggcaacatga cccagtcgca
    17341 gatcgcgcag gaggtcggca tctcgcagat gcacgtctcg cgtctgctgg cccgcaccct
    17401 ggcccaactg cgggagaagc tgctcgtcga ggaatgaggc ggcggaggac cggcgcggca
    17461 gcggcgacta ctccgacgcg cggcccggtc cccggatccc gagggcccgg gtcgtctcct
    17521 tgttgaccag cagcacgagc gaggcgacgg cggccgcggc gagcgcgatg cccgcgggga
    17581 tcgccatgct gtcggcctgg agcaggttgt aggccaccgg cagcaccatg atctgcgtca
    17641 tgacggcggg gccgcggctc cagccgcgca ggcccagcag tccgcgggcg gcgagcagcg
    17701 gcagcagcgc gagcaccatc agcgtgaccc cgccggtgac ggcctggctg cggtcgtccg
    17761 ggtcgccgct gatcccgagg accagcatcc acaggccgcc gacgaccagc gccagcccct
    17821 ccagcgcgac gagcgcggcg gcgtacgtca gccggcgcgg gcgggagaga ggggtctcgg
    17881 gggcgtcggg agtccggtca ctgctcaccc ctgaagggta gcccgcgccc tccgccggtg
    17941 tcccggaccg cgtgtccgca cgggcgcggc gcccgtgtcg aggctcacgg tcggatctct
    18001 tacccgatcc ccacctggcc tgtgcccggt accacccagt aggtacgctg caactcatgc
    18061 gtgcacttct cgtggtcaat ccggcggcaa ccactaccag tgcacggacg cgcgacgtcc
    18121 tcatccacgc gctcgcgagc gagatgaagc tcgaggcggt caccacggag taccgggggc
    18181 acgcgcgcga tctgggccgg caggccgcgg acagcgggaa cgtcgacctg gtggtggccc
    18241 tcggcggcga cggcacggtc aacgaggtcg tcaacggact gttgcacgcc gggcccgacc
    18301 ccgagaacct tcccgggctc gcggtggtcc ccggcggctc caccaatgtc ttcgcccgcg
    18361 ccctggggct gcccaacgac cccgtcgagg ccaccggcgc actgctggac gccctgcgcg
    18421 agaacacgga gcgcacggtc gggctgggcc tggccgccgg gacgccgggc acggaggacg
    18481 aggcggtgcc gtcgcggtgg ttcaccttca acgccgggct cggcttcgac gccggagtgg
    18541 tgggaagagt ggagcagcag cgtgagcacg gccgcagatc cacccattcc ctttacatcc
    18601 gccaggccgt ccgccagttg ttgggtgagt cacagcgccg gcacgggtcg atcaccctgg
    18661 agcggccggg tgcggatccg gtgaccgatt tggtgctgtc catagtctgc aacacggctc
    18721 cgtggaccta tctgggcaat cgcccggtgt acgcgtcgcc taaggcctcg ttcgataccg
    18781 ggctcgacgt actcggtctc agccgcctgt ccacggcctc ggttgcccga tatggcaccc
    18841 agttgctcac ttcgtccccc gaccggggcc cgcacggaaa gcacgcggtc tcactgcacg
    18901 acctggaccg gttcaccttg cattcgaagg cccctctgcc ccttcagatg gacggtgacc
    18961 acctggggct gcgaacaagc gtgacgttca caggcgtacg ccgtgcactg cgtgtgattg
    19021 tgtgagcaga aagggctgaa gtcctttcac tcgaacgttt aggccaggat ccaccccatg
    19081 gaagtacggc tgtgacctag tcgacaccga ggaatcaaaa aaaactttcc ggtaggggtt
    19141 gtatccgccg ctgaggtttg cgagtctcta cgtggcgatc gggacagccc gcaacaccgg
    19201 catccactga tcaccggaac ccctcttcaa acaacaggac cgcgccgggc aacctggctg
    19261 gtggcccttc acttgttgag ggattcgtga aagcgttcac attcacaagc aacttgcacg
    19321 taataccaag gagaggtagc agccatggac tggcgtcaca acgccgtttg ccgcgaggaa
    19381 gaccccgagc tcttcttccc catcggcaac accggtcctg cgctgctgca gatcgaggaa
    19441 gccaaggccg tctgccgtcg ctgcccggtt atggagcagt gtctgcagtg ggcgctcgag
    19501 tccggtcagg actccggcgt ctggggtggc ctcagcgagg acgagcgtcg cgccatgaag
    19561 cgccgcgccg cccgcaaccg ggcccgtcag gccaccgcct gacaacaccc gccccgcaag
    19621 cctcagcttg gcggcgcgtg tgcctgccgg cctgacaggg ccgacagcga gtacgcatct
    19681 cccgcccccg agccgcagcg cgcagtaccc ccgatgcgca gcacatgctg gcaacgagca
    19741 ttcgagcccc ggacccctga acggtccggg gcttcttgct gtccggcgcc cgcgcccgtc
    19801 cggtgtccgt aacacgcggt gtccgcaaca cgcggcgccc gcaccacctg gcgccggcga
    19861 tcgcccgcgc cgcccgtgcg ctatttctgc gcgcgcaccg ggatgtccag gatcacctgc
    19921 gtgccgcgct ccggcgcccg gaccatgtcg aacgtgccgc ccaactcgcc ctccaccagc
    19981 gtccgtacga tctggaggcc caggttgccc gaggtgtgcg gatcgaaccc gtcgggcagg
    20041 ccgacgccgt cgtcctggac ggtgaccagg agacggccct ccttcgtggt gccgccgcgc
    20101 acggccgaga cctcgacggt gccggtgtcg ccctcggtga acccgtgctc cagggcgttc
    20161 tggaggatct cggtgaggac catggacagc ggggtggcca cctcggcgtc caggatgccg
    20221 aagcggccgc tgcgccgccc ggagaccttg cccggggaga tctcggcgac catcgccagc
    20281 acccggtcgg cgatctcgtc gaactcgacc cgctcgtcca ggttctgaga cagcgtctcg
    20341 tgcacgatgg cgatcgagcc gaccctgcgg accgcctcct ccagggcctc ccggccgcgc
    20401 tcggactcga tgcgccgggc ctggaggcgc agcagggccg ccacggtctg gaggttgttc
    20461 ttcacccggt ggtggatctc ccggatggtg gcgtcctttg tgatcaactc acgctcgcgg
    20521 cggcgcagtt cggtgacgtc gcgcagcagc acgagcgcgc cgatgcgggt gcccttgggc
    20581 ttgagcggga tcgcccggaa ctggatgacg ccgtccctgg cctcgatctc gaactcgcgg
    20641 ggcgcccagc cgctcgcgac cttggcgagc gcctcgtcca cgggaccccg ggtcggggct
    20701 agttcggcgg tggtcaggcc gaggtgctgg ccgaccaggt cggaggccag gcccatgcgg
    20761 tggtaggccg acagcgcgtt cggggaggcg tactggacga tcccctcgcc gtccacccgg
    20821 atcaggccgt cgccgacgcg cggtgcggcg tccatgtcca tctgctggtc ggggaacggg
    20881 aaggagccgg ccgcgatcat ctgcgcgagg tccgaggcgc tctggaggta ggtgagctcc
    20941 aggcggctcg gggtgcgcac ggtgagcagg ttggtgttgc gggcgatgac cccgaggacg
    21001 cgcccctccc gtcgcacggg gatcgactcc acccggacgg ggacctcctc gcgccactc
//
