LOCUS       NZ_BMSI01000002        32045 bp    DNA     linear   CON 02-AUG-2024
DEFINITION  Streptomyces asoensis strain JCM 4185 sequence02, whole genome
            shotgun sequence.
ACCESSION   NZ_BMSI01000002
VERSION     NZ_BMSI01000002.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces asoensis
  ORGANISM  Streptomyces asoensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 655051)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014649075.1-RS_2024_08_02
            Annotation Date                   :: 08/02/2024 04:45:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,813
            CDSs (total)                      :: 7,736
            Genes (coding)                    :: 7,563
            CDSs (with protein)               :: 7,563
            Genes (RNA)                       :: 77
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 53 of 173
            Pseudo Genes (incomplete)         :: 140 of 173
            Pseudo Genes (internal stop)      :: 10 of 173
            Pseudo Genes (multiple problems)  :: 28 of 173
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:21:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 473386
            Orig. end                         :: 505431
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMSI01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..32045
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="nucleoside"
                     /region_number="5"
                     /rules="(LipM or LipV or LipU or TunD or pur6 or pur10 or
                     nikJ or nikO or truD)"
                     /tool="antismash"
     cand_cluster    1..32045
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(LipM or LipV or LipU or TunD or pur6 or
                     pur10 or nikJ or nikO or truD)"
                     /kind="single"
                     /product="nucleoside"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..32045
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:22045]"
                     /cutoff="20000"
                     /detection_rule="(LipM or LipV or LipU or TunD or pur6 or
                     pur10 or nikJ or nikO or truD)"
                     /neighbourhood="10000"
                     /product="nucleoside"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..22045
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(LipM or LipV or LipU or TunD or pur6 or
                     pur10 or nikJ or nikO or truD)"
                     /neighbourhood="10000"
                     /product="nucleoside"
                     /protocluster_number="1"
     misc_feature    140..154
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.46"
                     /tool="antismash"
     misc_feature    complement(827..841)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.1"
                     /tool="antismash"
     gene            938..1921
                     /locus_tag="IE189_RS08170"
                     /old_locus_tag="GCM10010496_16530"
     CDS             938..1921
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (47-227). E-value:
                     7.6e-09. Score: 27.0. Matches aSDomain:
                     nrpspksdomains_IE189_RS08170_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005473672.1"
                     /locus_tag="IE189_RS08170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_16530"
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_189919213.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 7.7e-08, bitscore:
                     27.0, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFEEFQAFRQRQLCASSALLDAAETNLYRALAALRPEQPAEMNT
                     VHRCDLARAWLRRYALPEEWSGRAMVCRGVRHGLAVVFRQLHAEKARLWLPGDVYPVYF
                     ELARAAGLEPASYPTLPVPVLPGSPADHRPEYLLLANPSRPLGRYLSDDECTAVISWLE
                     ASPRRRLLIDSVYDLGAPFAPGTRRLLDTGRAVLLHSVTKGWLWPRTFGIVVLDPAQTA
                     WAEAFRADPPTPAQLRLADRLLTGHGEVPRQIVDDLAARAERLFDRLPDDVLTAIPAAS
                     RTCPGNYFFPVGIPAETLRRDYGVLAIPVGVFGDSAWPGSVLTSLG"
     aSDomain        1079..1618
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS08170_Aminotran_1_2.1"
                     /evalue="7.60E-09"
                     /label="IE189_RS08170_Aminotran_1_2.1"
                     /locus_tag="IE189_RS08170"
                     /protein_end="227"
                     /protein_start="47"
                     /score="27.0"
                     /tool="antismash"
                     /translation="RCDLARAWLRRYALPEEWSGRAMVCRGVRHGLAVVFRQLHAEKAR
                     LWLPGDVYPVYFELARAAGLEPASYPTLPVPVLPGSPADHRPEYLLLANPSRPLGRYLS
                     DDECTAVISWLEASPRRRLLIDSVYDLGAPFAPGTRRLLDTGRAVLLHSVTKGWLWPRT
                     FGIVVLDPAQTAWAEAF"
     gene            complement(1924..2370)
                     /locus_tag="IE189_RS08175"
                     /old_locus_tag="GCM10010496_16540"
     CDS             complement(1924..2370)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016430327.1"
                     /locus_tag="IE189_RS08175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_16540"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_189919214.1"
                     /transl_table=11
                     /translation="MTDLRIQEVDDDASIHDWQHVHNLIIPGDVLSLDDVRARTGRNRM
                     EVAHLGDVLIGCTTVRPPTEDNGATATVIARVLPEHRRRGLGTRLYERALGQARALDAQ
                     VIETVVLASNQDGLRFAGRHGFVELERYLLRDGDTVPWIDLRLA"
     gene            2538..3068
                     /locus_tag="IE189_RS08180"
                     /old_locus_tag="GCM10010496_16550"
     CDS             2538..3068
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470205.1"
                     /locus_tag="IE189_RS08180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_16550"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_189919215.1"
                     /transl_table=11
                     /translation="MPELIAPAARLRSSWLAACAEWPPGAHQDGTGLRLAPEGDLRDPD
                     VFRTWVERLRRQSDRSVAVGEGRVHATHWWIVEDDSYLGAIDVRHYLNALLLDVGGHIG
                     YSVRPSARRRGLATWALGAVLPRARALGLDRVLVTCDDDNTGSARSIERNGGVLEDVRA
                     AGSGLKRRYWIDL"
     gene            complement(3040..4404)
                     /locus_tag="IE189_RS08185"
                     /old_locus_tag="GCM10010496_16560"
     CDS             complement(3040..4404)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FMO-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1092: hypothetical
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009077150.1"
                     /locus_tag="IE189_RS08185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_16560"
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="WP_189919216.1"
                     /sec_met_domain="FMO-like (E-value: 8.6e-94, bitscore:
                     310.0, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.9e-12, bitscore:
                     42.2, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNVCVIGAGSSGIAACQVLADRGIAYDCFELGSQVGGNWRYLND
                     NGQSSAYRSLHINTSRQIMEYAGFPMADDCPVYPGHAHIARYFDAFVEHFGLRPSIRFR
                     TEVVRVVPDGDRWTVTSRHRDTGALETGVYDAVLVANGHHWKPRWPEPEIPGVAGFAGT
                     RIHSHHYRSPEPFADRRVLVLGIGNSACDIAVEVSRVSRQTFLAMRRGAHILPKYLFGR
                     PTDHLTHSWLARMPLAVQDRGLHLLLRLSRGRLADYGLPEPEHRVLAAHPTISDDLLSR
                     LGHGDITVKPVPRRIDATQVAFDDGSVEDIDTIICCTGYDIAFPFLDDEVIDVSGNDPG
                     LYHRVVSPDRPGLYFIGLVQPLGAIMPLAQAQSHWVADLLQGRCALPGRDGMLAEIRAH
                     RARTARRYVASPRHTIQVDARAYLRELARERARSAVRRGRGRRFTLPTGRSSTAS"
     misc_feature    complement(4417..4432)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.48"
                     /tool="antismash"
     misc_feature    complement(4516..4531)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.49"
                     /tool="antismash"
     gene            4590..5243
                     /locus_tag="IE189_RS08190"
                     /old_locus_tag="GCM10010496_16570"
     CDS             4590..5243
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020126485.1"
                     /locus_tag="IE189_RS08190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_16570"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_189919218.1"
                     /transl_table=11
                     /translation="MPTPTWDRLSPARRERVLVAAMDEFGTHGYSTGSLNVIAREAGVA
                     KGSLFQYFSGKLDLFAYVAEQTSLRVYAHMQPWLDGYDESGDFRTYLVDALEAWLDYFA
                     GQPLERGVTAATNMEMDPAVRDAVRAPVNAVYLAGLRPLLERAVATGDLRKDADLDALL
                     SILLVFLPHLALLPHLSGGDGPLPLTSVDPQARRANLERLVTPLLADFTQEDDG"
     gene            5240..6952
                     /locus_tag="IE189_RS08195"
                     /old_locus_tag="GCM10010496_16580"
     CDS             5240..6952
                     /GO_function="GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020126486.1"
                     /locus_tag="IE189_RS08195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_16580"
                     /product="GMC oxidoreductase"
                     /protein_id="WP_189919221.1"
                     /transl_table=11
                     /translation="MSGFDYDVLIIGSGFGGSVSALRLTEKGYRVGVLEAGRRFADTEL
                     PQTSWRLRRYLFAPRLGCTGILRMTLLGDVLVLSGAGVGGGSLGYANTLYEPPDAFYEG
                     SHWASLTDWRRELAPYFAQARRMLGVTPNPLVSEADVLLRDTARDLGCGDTFRTTPVGV
                     HFGPAGALPGAEVPDPYFGGAGPARNACTHCGACMTGCRHNAKNTLPKNYLGLAERAGA
                     RVLDRRTVTGVERRAGGWAVTSVRTGVLPGRGRQRLTSRHVVFAAGALGTQRLLHTLKD
                     DGGLPDISPRLGRLTRTNSEAVLGVRAPGRDADYSRGVAITSSVQLDDTTHVEPVRYGR
                     GSNLLALLGAMLVDPVPGRSRLRVGLAAMARDVRRLPALHNPRRWSQQTVVLLVMQTLD
                     NSVSTRLRRTRTGRRRLTSRLGEGAPNPTWIPAGHRAARTTAERVGGQACGTWADLFDV
                     PTTGHLIGGCTVGDSPLTGVIDPYHRLHGYPGLHVVDGSTISANLGVNPSLTITALAER
                     AAALWPNKGESDTRPEPGRPYRHVAPVPPRRPAVPTTAPGALRLPPPHGTDAP"
     gene            6949..7560
                     /locus_tag="IE189_RS08200"
                     /old_locus_tag="GCM10010496_16590"
     CDS             6949..7560
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018066.4"
                     /locus_tag="IE189_RS08200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_16590"
                     /product="acetoacetate decarboxylase family protein"
                     /protein_id="WP_189919223.1"
                     /transl_table=11
                     /translation="MTVYPDEPWHLAGQMYVSLWLVPRAELPPVAPGTRPFRFGGRGLV
                     AAAWVVYENDSVLHYDELLSAVLVRDGARLRVCITDIWVDSEASMAGGRALWGIPKEMA
                     TFEVRRAHGASFVAKTGEGTLATARFTARGRLPGRPPLAYRLAQSLDGRLKTTRVRSRA
                     TLRPARAEWTVPDDSRLAALVRRAPLLSLTLRDFTLRFGG"
     misc_feature    7868..7879
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.27"
                     /tool="antismash"
     gene            7882..8817
                     /locus_tag="IE189_RS08205"
                     /old_locus_tag="GCM10010496_16610"
     CDS             7882..8817
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020126488.1"
                     /locus_tag="IE189_RS08205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_16610"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_229901138.1"
                     /transl_table=11
                     /translation="MFRTLLRSMTAVLLTAAAALTLAPGAEAHPASPTVRATDPSTAGS
                     FPVAYTDLTVSAAGRSYSARVWYPGTTAGANAPVAAGAHPGLAFGHGFFQAITQYESLL
                     KHYASWGVITVAPKSQGGLFPSHSAFADDLNAALTWLTTQNTTSGSRFADRVDTGKLAL
                     SGHSMGGGAALVAAGRNPAVKSVTTLAAAETNPSAVAASATLGIPVQYVGGSADSIAGV
                     AANQQKMYDAKPSHTQLRVITGGFHCGFEDSSGIGCDSGTVTRAVQLKLTYGVTTSWLL
                     HTLGADTSLYDQVWGSAAQNLPGVVYSAKP"
     misc_feature    9078..9087
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            9216..9935
                     /gene="thyX"
                     /locus_tag="IE189_RS08210"
                     /old_locus_tag="GCM10010496_16620"
     CDS             9216..9935
                     /EC_number="2.1.1.148"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_function="GO:0050797 - thymidylate synthase (FAD)
                     activity [Evidence IEA]"
                     /GO_process="GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thyX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018544886.1"
                     /locus_tag="IE189_RS08210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_16620"
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="WP_189919553.1"
                     /transl_table=11
                     /translation="MESPRIELRSDITVELVDSSASDLAVVKAARVSTAGEDANDELYD
                     GGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGA
                     AFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIARE
                     IARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAK
                     LMPVTHEAFTAFGRVSP"
     gene            10001..11338
                     /locus_tag="IE189_RS08215"
                     /old_locus_tag="GCM10010496_16630"
     CDS             10001..11338
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     nucleoside: nikO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012497.4"
                     /locus_tag="IE189_RS08215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_16630"
                     /product="hypothetical protein"
                     /protein_id="WP_189919224.1"
                     /sec_met_domain="nikO (E-value: 3.4e-260, bitscore: 858.5,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEVNGGKRIAGSVRTSGFKHSLVTSAAAAVAADADVVLDNCPDI
                     VETDVLSRVFTTLGGRARYAEGTLTLNGSGIEHNVLPADLVSSIHGSLYLVPGLVARLG
                     SVHLPASGGCRIGEGPKGRPVRHVLDVMERFGATGGTTAEGGLKVRAARLTGCEIDLLD
                     YTRNRALMSGPLYGGATKTALLTAAAAEGVTTLHHLYPKPDVVALIDVLRELGTDMTWT
                     GPETLVIRGSGIGALRRDVRYTLPPDLIEVVTWICAAVTVGDGPVHITGPGMDRAVAAL
                     APEFDVLRRMGVVTDHEADSVTAHPAERPLAPVEVLAASRGVFSDSQPFFALMAGWAEG
                     ATLISEAVWEHRYGYVPGLTALGMDAVQDDYALRVDGVRTPHRTGQDLTATDLRAAAVL
                     LLAALAVPGRTVLRNTHHLDRGYRDIVGDLRSLGADVTPAADPAAG"
     gene            complement(11394..11960)
                     /locus_tag="IE189_RS08220"
                     /old_locus_tag="GCM10010496_16640"
     CDS             complement(11394..11960)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742825.1"
                     /locus_tag="IE189_RS08220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_16640"
                     /product="adenylate kinase"
                     /protein_id="WP_189919225.1"
                     /transl_table=11
                     /translation="MTEPADPRRILIAGISGAGKTSLAAALSQRLGIPHIEMDALYHGP
                     HWSRRAEFTDDVARFTASEAWVCDAQYHWIVGDLLAARTQLFVWLDLPRHTVMHRVIRR
                     SLSRVLLRRPLWHDNTETWRALLFSPRHPVRWAWSRHGTRRAETAAWFARHPDVPVVRL
                     RTAAQARRWLRSLPPAGRTHDGSRA"
     gene            complement(11957..13228)
                     /locus_tag="IE189_RS08225"
                     /old_locus_tag="GCM10010496_16650"
     CDS             complement(11957..13228)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="IE189_RS08225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_16650"
                     /product="MFS transporter"
                     /protein_id="WP_189919226.1"
                     /transl_table=11
                     /translation="MDATVHLASTRPGQRPPAHRPHARRWYLAALFADAVGNGLWTPLA
                     LIFFTRAQHIPLDVTGAALTAGGLIGLLTGPLAGTLVDRWGALPLVQLSNVLRGAVFLV
                     YPLITSVGQLIALAAVLAACERLFWTANTPALEQVVGKDGLLPVLATQNMLRTAGWMTG
                     AGLAAVLSAALLQHPGRLHLIAWLNGATFLAAALLMLGVRVPRRTGAPAASRPAPKATG
                     PAWRRTLADRPFLLLCLTQLAFALMTDSLTVMLPLVALDVLHGPSWLPAAALITSSVAL
                     LLAQKQAVRRFGGHGSALRPLRLACLVFAVAFLLLAPAGRLTPGWAVPVVLGAAVAGAV
                     ADALFAPVMTVLANAAAPEEYKGRYSATFQLAWGAAAVLAPAVGAFLLTAGNAVLWLTL
                     VALGAATAALTALVPRRGEGDTPA"
     gene            complement(13382..14224)
                     /gene="argB"
                     /locus_tag="IE189_RS08230"
                     /old_locus_tag="GCM10010496_16660"
     CDS             complement(13382..14224)
                     /EC_number="2.7.2.8"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003991 - acetylglutamate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1174: acetylglutamate kinase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019890445.1"
                     /locus_tag="IE189_RS08230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_16660"
                     /product="acetylglutamate kinase"
                     /protein_id="WP_189919227.1"
                     /transl_table=11
                     /translation="MSTAPAAPARPLAGRTVLIKCGGSVLDEGDAGRTFAEDVAELADA
                     GTRVVVVHGGGPQIDTHLERLGIQPVFRHGLRVTTPPTMEVVRMVLSGQVQRRLVGLLN
                     RERRLAVGLTGEDARTFTAADRQVFHGGQRVDLGLVGDIVDVDDRLLRTLLDAGLVPVV
                     SSIARSADGSGVRNVNADLAAAALAAALRADTLLLLTDVAGLYPGQPDRGEVLDRLTAA
                     EADALLPRLTGGMIPKVQACSQAVRAGVATARIADGRIPHAVREHLLTGRRTGTTVSP"
     gene            complement(14221..15942)
                     /locus_tag="IE189_RS08235"
                     /old_locus_tag="GCM10010496_16670"
     CDS             complement(14221..15942)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Carbam_trans_N"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980151.1"
                     /locus_tag="IE189_RS08235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_16670"
                     /product="carbamoyltransferase N-terminal domain-containing
                     protein"
                     /protein_id="WP_189919228.1"
                     /sec_met_domain="Carbam_trans_N (E-value: 1.1e-66,
                     bitscore: 220.8, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITCGLKLTHDGAVALVDDRRLVLSVEMEKLANNPRYSAIGDLGI
                     VPTILAEHGYRMEDVDAFVVDGWDGDESGTVDTADRGQPLELVVGPYRESRTSPDLLRP
                     SVSGTFTVDGVPYPYTSHTHAAGHVLSTYCTSEFARRGEPAFVLVWDGGMFPRLYWVDP
                     EAGVENGGSLFPLIGHTYATAGHHFGPFRRDRQSANVDDLSVAGKLMAYIALGKPSEAV
                     LEVLASVFHDHYENEASPAAAEHSRTVGGFGSLFEPSMPPLHDFFRAVREQVQPFAVSD
                     EDVLASVHEFLQNLLLERLDARIRAWKGDGPWNLCFAGGCALNIKWNSALRALPLVRRM
                     WVPPFPNDAGSAIGAAVLGAIGGRNAVPALEWHTRLGPALTPTTGTPQGWTARPCSPDE
                     LARVLHTGQEPVVVLHGRAELGPRALGGRSILAAATDAAMKETLNQVKGREYYRPVAPI
                     CLVEEAPEIFDPGTPDPHMLYDHAVRPGWTSRIPAVVHLDGTARLQTVSPDDDALLSDI
                     LTAYHRVSGVPVLCNTSANLNGSGFFPDAASAMAWGKVDRVWSEGVLYQRGGAATG"
     gene            complement(15939..16445)
                     /locus_tag="IE189_RS08240"
                     /old_locus_tag="GCM10010496_16680"
     CDS             complement(15939..16445)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025054.4"
                     /locus_tag="IE189_RS08240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_16680"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_189919230.1"
                     /transl_table=11
                     /translation="MREDVVVRPALATDAPGIARLSEPFVADDLLVARSGTQFRNRIGD
                     YLTAVHDSRVIGCVGLTRLGDDLLLYNLCVAADRQGLGIGGRMVERADALAALGGCRFL
                     LAASKHSGRWFVRHGFTRTEPQHMPAVWADLLPPGRGSHLYRRPVAPRTAPPAFTPPRQ
                     GAERS"
     gene            complement(16438..17205)
                     /locus_tag="IE189_RS08245"
                     /old_locus_tag="GCM10010496_16690"
     CDS             complement(16438..17205)
                     /NRPS_PKS="Domain: PKS_KR (6-171). E-value: 4.8e-13. Score:
                     41.4. Matches aSDomain:
                     nrpspksdomains_IE189_RS08245_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009720572.1"
                     /locus_tag="IE189_RS08245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_16690"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_189919232.1"
                     /sec_met_domain="adh_short (E-value: 1.2e-35, bitscore:
                     118.3, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSQELGTVVVSGASSGFGRVTARRLAAQGHTVIAVARRADRLAE
                     LADGEGPGRVLPAVADVTDLDALERALDEHLPHCPPVVGLVNNAGLSSGFGPVQSAKVD
                     DWRRMVDTNVSGLLHTTTLLLPRLIAGGRGHIVNIGSIAARYPYAGGNVYAATKAFVHQ
                     LSLSMRTDLEGTGVRVSCVAPGMARTEFALVRYDGDQERADRLYDGVSPLSPDDVADAV
                     LWCLSRPPHVNVNMIEIMPTDQPFGLGFARRHA"
     aSDomain        complement(16693..17187)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS08245_PKS_KR.1"
                     /evalue="4.80E-13"
                     /label="IE189_RS08245_PKS_KR.1"
                     /locus_tag="IE189_RS08245"
                     /protein_end="171"
                     /protein_start="6"
                     /score="41.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="GTVVVSGASSGFGRVTARRLAAQGHTVIAVARRADRLAELADGEG
                     PGRVLPAVADVTDLDALERALDEHLPHCPPVVGLVNNAGLSSGFGPVQSAKVDDWRRMV
                     DTNVSGLLHTTTLLLPRLIAGGRGHIVNIGSIAARYPYAGGNVYAATKAFVHQLSLSMR
                     TD"
     CDS_motif       complement(17089..17184)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE189_RS08245_0001"
                     /evalue="3.80E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE189_RS08245"
                     /protein_end="39"
                     /protein_start="7"
                     /score="16.3"
                     /tool="antismash"
                     /translation="TVVVSGASSGFGRVTARRLAAQGHTVIAVARR"
     gene            complement(17263..17994)
                     /locus_tag="IE189_RS08250"
                     /old_locus_tag="GCM10010496_16700"
     CDS             complement(17263..17994)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021527.4"
                     /locus_tag="IE189_RS08250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_16700"
                     /product="2OG-Fe dioxygenase family protein"
                     /protein_id="WP_189919234.1"
                     /transl_table=11
                     /translation="MLTRPTAALSSPADITGDLVRTGFSMVPGSDMRVPAALQDSLKTL
                     AASYDDLPADPYLPDGGNYRYRRHTRYTWRPATGELLVADNPGYFQTVENNAFAGGQWR
                     KYEELTDEVREGAFLTALIDFNVGRLPLPEVEQWAVQVHCVRIVARDDAQGRPTPEGVH
                     RDGCTYVSLHMVNRHNISGGRTSVYTPEHELITEKVFTDCLDSFFGDDPRVRHGVADVS
                     VADPSLGEGTRDMLLMSYDPM"
     gene            complement(18051..18692)
                     /locus_tag="IE189_RS08255"
                     /old_locus_tag="GCM10010496_16710"
     CDS             complement(18051..18692)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025024.4"
                     /locus_tag="IE189_RS08255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_16710"
                     /product="2OG-Fe(II) oxygenase"
                     /protein_id="WP_189919236.1"
                     /transl_table=11
                     /translation="MTLIDLQALRDARLEKDPYHYAVVPSSFRDDDTARTLNDGFAADG
                     FVRSERRPGSGRGKHYLMHNRTLVSEGRQHREAVDTLPEAWRLLVDEVTSDDYRDALVE
                     LTGADLDGCTVEARMTRYSSGCWIQPHTDRPDKAVTHLFYFNDTWRSEWQGDLHVLRGP
                     DMKDVARRVLPLLGTSVVLVRSDDSWHGVPPVSEGCPDDRRALLVHFART"
     gene            complement(18679..19500)
                     /locus_tag="IE189_RS08260"
                     /old_locus_tag="GCM10010496_16720"
     CDS             complement(18679..19500)
                     /EC_number="3.1.3.48"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024744.4"
                     /locus_tag="IE189_RS08260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_16720"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_189919238.1"
                     /transl_table=11
                     /translation="MTTGARRHPAERTPAAAARPTRGSRTVALPGLPNVRDSAGLPGPD
                     GARLRSGVLYRGPAPSPLTAPALDDLGIRTVVDLRTAFEQGIEDGPAGMRARLLRRPVG
                     GNMSRIRGVRRPPPSAYLFNYRSMLTLAAPVAVEIIGLLAEPDQDPVYVCCTVGKDRTG
                     VVSALTLRGLGVRLAAVAGDYSLTGRAYRALGPQDPRPQWSYEGSLEELQIRTASPAWT
                     MRSLITGIEDEHESVARYLERQHGLSPKTRLRAVRRVFEHHAPRRERHDAD"
     gene            complement(19497..20639)
                     /locus_tag="IE189_RS08265"
                     /old_locus_tag="GCM10010496_16730"
     CDS             complement(19497..20639)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (72-367). E-value:
                     9.7e-32. Score: 102.4. Matches aSDomain:
                     nrpspksdomains_IE189_RS08265_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012382.4"
                     /locus_tag="IE189_RS08265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_16730"
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_189919240.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 8.4e-31, bitscore:
                     102.6, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAYPPREEEPAQAGAPSPFRVESSGRYRSRRTRRPGEVNLKSSG
                     LLDARAADLHRRTLAGLDPLEVLTYPVLRDVYAEIADHLDADPDGLVLTAGSDPGLGLL
                     VRAFPRARRIVLHHPNYEGWQKFARIAGCRLDQVPPDPGTGRFSLADLAARLRGGPPAF
                     VVVTQPHSFTGQVHARAELESLARAVADHGSLLVLDTAYLAFTEGGEKEIGTLTGRPHP
                     PHVVRVNTFSKCFGLSGARIAVLSSHPDTVRPLLDLDPEGPVSGTAVALLRACLREQPL
                     FEEIWAGVREVREHFSRGVEEALPGWRALPGGGNFATWQVASPREAADAAAHLHAHGYV
                     VRAVPSTPDSPAAVRIGVTDRSTADRVTDLLLRREQAVAR"
     aSDomain        complement(19539..20423)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE189_RS08265_Aminotran_1_2.1"
                     /evalue="9.70E-32"
                     /label="IE189_RS08265_Aminotran_1_2.1"
                     /locus_tag="IE189_RS08265"
                     /protein_end="367"
                     /protein_start="72"
                     /score="102.4"
                     /tool="antismash"
                     /translation="LRDVYAEIADHLDADPDGLVLTAGSDPGLGLLVRAFPRARRIVLH
                     HPNYEGWQKFARIAGCRLDQVPPDPGTGRFSLADLAARLRGGPPAFVVVTQPHSFTGQV
                     HARAELESLARAVADHGSLLVLDTAYLAFTEGGEKEIGTLTGRPHPPHVVRVNTFSKCF
                     GLSGARIAVLSSHPDTVRPLLDLDPEGPVSGTAVALLRACLREQPLFEEIWAGVREVRE
                     HFSRGVEEALPGWRALPGGGNFATWQVASPREAADAAAHLHAHGYVVRAVPSTPDSPAA
                     VRIGVTDRSTADRV"
     gene            complement(20636..22045)
                     /locus_tag="IE189_RS08270"
                     /old_locus_tag="GCM10010496_16740"
     CDS             complement(20636..22045)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     nucleoside: nikJ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="other (smcogs) SMCOG1277: Radical SAM
                     domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF015983.4"
                     /locus_tag="IE189_RS08270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_16740"
                     /product="radical SAM protein"
                     /protein_id="WP_189919243.1"
                     /sec_met_domain="nikJ (E-value: 5.4e-267, bitscore: 880.7,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 6e-17, bitscore: 57.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEHVTPAGRAAALAPGSRILVVWPPQILSYFNAGHHLALYQVAG
                     HLRTALPDSEVTVLDATVLRRTWKDIGNDLFQQRYDAIAVMNDFDGIDGLRRFVSYARA
                     LSPGTPIVTFGRLSGVNPLFFQQLDIDAVAENGDFEAAVLAALRFFDGETVTAPGVHLR
                     HADGSWHAPSSPGAVLPAQEWYLPTPDEIPYQRYDELYHDDANKFCGIPQRRELVVPAA
                     RGCPIGCSYCEVHPIFGRKERRLTVERTVEYIEQSFRTASFEYVAFYAPTFTLDRRWTM
                     DLCERLTADGARFPWKCATTMHHLDEDLVRAMGRAGCVRISVGLETLDPHGHGALPRSK
                     HKSQQDLENLAGWCAQAGIELNCFVIVGLPGTSVEGVRHTIATVQALGGRARPTVYAPW
                     EAARPDLSDEEMAAFNRQLFVPGTHDLDPAQLRDAYEVVFGPQPDVTAVFERIPARAAG
                     ADGDPVLLGAS"
     gene            complement(22038..23330)
                     /locus_tag="IE189_RS08275"
                     /old_locus_tag="GCM10010496_16750"
     CDS             complement(22038..23330)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014805.4"
                     /locus_tag="IE189_RS08275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_16750"
                     /product="acetyl-CoA carboxylase biotin carboxylase subunit
                     family protein"
                     /protein_id="WP_189919245.1"
                     /transl_table=11
                     /translation="MFLLLNNKPILHRVPEWFPQARQELIVVSTRSGLGTSAFPELARG
                     FRHLHLVSSLDRPGLEEDLVALCRRFGVRRVLSTGEREVLPAATLRERLGLPGQDVACA
                     TAYRDKYTMKSLLTEAGIPVAPMRRLASPADLDAFADEAGFPLVVKSRLSGGSNGTRVL
                     WDGDALTAFTDDWAAGRTAAPDLAEAWVEGDFYHINGLMRDGRILLAQPSYQPYSDWFS
                     VAYDAPGMSGMMPDEDPMSARLRDTAAKVVATMPAVPGVCAFQVEFFHTPDDRLVVCET
                     ACRAGGSRMVETHEDTLGVHLHGASLLGQAGRSDQVTIRPTGRRQGYARFPSAHGVLRH
                     LPRRSPLPQTLLYTATGEEGRHYDPATSLGSSVAEIVVSLTGPDTAAELLAVETWWESA
                     VVWQDRRNPVPDRFKSVHRVRPDTRERALHV"
     gene            complement(23360..24181)
                     /locus_tag="IE189_RS08280"
                     /old_locus_tag="GCM10010496_16760"
     CDS             complement(23360..24181)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040351.3"
                     /locus_tag="IE189_RS08280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_16760"
                     /product="DUF6202 family protein"
                     /protein_id="WP_189919247.1"
                     /transl_table=11
                     /translation="MNALALSAAEQQDLDARVGKEIDAARLRRADNAFFGEARKAESVT
                     PEAALAIAHRWRAMTKAFMFTTLSGLGVMARRFQGQDAPDHELLAAFQTVYQVIGDDLD
                     NAAPAFREVAPRGPAGIHYVWWEDTVLKPVAAHVAEEDRQSAAVLPRAVTGLLDSMDRL
                     ATHPLGAAVQLRVVEDIALDIAVGFRRLYAKVEVPGTTLFAGRDDLAWVDSHIKAETMH
                     AAQVSDEDTGMTRLVADREQAEEFLTAVREYAAHWSAALETYAQALRDGHA"
     gene            complement(24239..25351)
                     /locus_tag="IE189_RS08285"
                     /old_locus_tag="GCM10010496_16770"
     CDS             complement(24239..25351)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019355592.1"
                     /locus_tag="IE189_RS08285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_16770"
                     /product="DUF6421 family protein"
                     /protein_id="WP_189919249.1"
                     /transl_table=11
                     /translation="MDDMNPVFAEVDRLRRRIGDRTSLRDPQFLKELADRLERSPALSE
                     RPITRALAADLRVFRPGQVLEATKEHINSRRDNDVFSLFDASYFPSLSLDYLTYETLPT
                     DPHLAERYASNTLPVNITGASEGFGARVVVALFPENQLDGHQGPDDMIFYFIDKFVERH
                     LRITRRMIEAVTAPDSFPLLHGMTDEQVEQASSWWVRLHEYHHRQGDMPVPQYLSAKKR
                     KPLAGLEELRVDVSGILACEDDEKLPRQQARQAAQFILAERLLRYAVEGIPRPNYDAVA
                     SQLLFNYCESHGGLKVKDGVIHVASDIVAVLREFLGEIQRMESRIHEEPVTSVTARMLA
                     FTNSYTDYDAQARDYRHIAFFADVKERLGV"
     gene            complement(25374..26021)
                     /locus_tag="IE189_RS08290"
                     /old_locus_tag="GCM10010496_16780"
     CDS             complement(25374..26021)
                     /EC_number="1.14.11.-"
                     /GO_function="GO:0008198 - ferrous iron binding [Evidence
                     IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025024.4"
                     /locus_tag="IE189_RS08290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_16780"
                     /product="2OG-Fe(II) oxygenase"
                     /protein_id="WP_189919251.1"
                     /transl_table=11
                     /translation="MLRKDTPVLHVDAPFTLHLAQGLLTKDVVSDLYATAPVNRTAAIS
                     RVDPEHEKQYKMNLFYLMVNNQRSRASGELPAVWRSLLDDLAGVEFTDWLSESTGIDLH
                     GLSQDIGVYTHVDGDFISVHKDKADKAITAILYLNPEWPTNAGGEFEVHFSGDPDDDHV
                     FRLPPRPGQLLAFPPTDKSWHAVSRVDSGEEITRLTVQLEYWFEHVDRYSTD"
     gene            complement(26026..26661)
                     /locus_tag="IE189_RS08295"
                     /old_locus_tag="GCM10010496_16790"
     CDS             complement(26026..26661)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE189_RS08295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010496_16790"
                     /product="2OG-Fe(II) oxygenase"
                     /protein_id="WP_189919253.1"
                     /transl_table=11
                     /translation="MIRASAQVVTHAEPHVHHTGLHLIDAEDLRRLNAEPPAMSEFIRA
                     VKEAPEFDKHYRLWLMTVHQDGRHTPKAEKLPPAWAELLDEVVQDSFRTWLSSRTGVDL
                     EGAALEVNVSLRDPGDYRNVHRGKPDRAMNAVLVLSEHWPENGGGTYDLWESPDRDAPA
                     RSVLPVPGSLYTVVPSDASWHSVSPVAQDAPGSLLTLALGYSMPERRS"
     gene            complement(26845..29733)
                     /locus_tag="IE189_RS08300"
                     /old_locus_tag="GCM10010496_16800"
     CDS             complement(26845..29733)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670558.1"
                     /locus_tag="IE189_RS08300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010496_16800"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_189919255.1"
                     /transl_table=11
                     /translation="MDRHIAFGVLGPIRIWRDGAELPPGPPKQRAVLALLLLEAGQPVS
                     LSRIVDALWPAGAPSSAANIVHRHVGNLRKLLEPHLAPRAPGRLLVRRVGGYAIDVDAG
                     TLDLLRFRELAQRARAARAGGDTEAAAELFTQALSLWRGEAAAGVPQELRGHPAFFAVD
                     SEHLAVLREGADLVLATGAPERMLPLLQSAAALHPLDESLHVRLVQALAATGRQAEALA
                     LYDTMRARLAVQVGVEPGPELSAVRARLLHDVQTPPDGTDDGRPLSGTDLPPRQHAPES
                     APAVRPTQLPPDLCTFVGRRTELARLTELLDALDDGRPAAASVVISAIDGMPGVGKTTL
                     AVHVAHRLAHRFPDGQLYVNLRAFDVSESAVPAAEVLRSFLTALGVPARDLPPDTDSRV
                     ALYRSLLAGKRILILLDNALDSEHVRPLMPGSSSCLVVITSRTQLRGLVATHGARPITL
                     GLLSREESREVLAGRVGGERTAAEPAAVDEIIDLCGRLPLALAIVAAHAATQPDLPLAS
                     VAAALLDDRDSLDGFAGEDRYTDLRTVFSWSCRSVGPQAARLLRLLALHPGPDISAAAA
                     ASLAALPARRVRALLATLNGAHLLARSGPQRFAFHDLLKVHALEQSRELEDEDTRQLAV
                     RRLLDHCLHTAYAAAEALIPNRIEAPLEPEAAPGVAPEPIGGRQEAMAWLDRELPVLLS
                     AVPYAQRRGFPQHAWLLAQALELHLDRQGRWQDQTAVQRTALEAAISLKDPVREAQACR
                     ALGFAWGRLCEDDRADAFLRRALTLFTEAGDAAGQARTRRQMAFLANARGRHTEALRHY
                     EHALALYRGIRNLGGQAVVLNETGWTHILLGDHERAITWCDRAVSLHRAIGDVNGEAAA
                     WDSLGLAHHHLGHHPEALDCYRRALGLYRHMNDRYLQADTLLHLGDTHEARGAHITAVL
                     VWRQAVRILDDMGHPEAKQARARLEDTPHHPR"
     misc_feature    complement(28651..28653)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(29275..29277)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    29865..29875
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     misc_feature    29945..29958
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.54"
                     /tool="antismash"
     misc_feature    complement(30120..30135)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.23"
                     /tool="antismash"
     misc_feature    complement(30513..30528)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.92"
                     /tool="antismash"
     misc_feature    31603..31618
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.73"
                     /tool="antismash"
ORIGIN
        1 cggcacaccg tcgctacgcc gacacgacac cgcgctcggt gtcggtcctg ccggtcgcgt
       61 ccgcctgcca ggcccggtgc tctttctgct tctcctcggc gtcgatctcc agcgaccagg
      121 cgcccgcccg ggtcccgtgg gacgcggtcg gccactggct ggagcgcgcc cgtgcggcgg
      181 gtgccgagcg tgcggtgatc accggcggcg gggagcccac gctcataccg ttcgaacagc
      241 aggtgagact ggtgtccgcg tgctcggcgg ccttcccgaa ggtcgtcctg atcaccaacg
      301 cgcacaccct ggcgaaaggc gagcacgccg accgtgccga ccgcctcgcc gcactgagcg
      361 ccgcgggact gagcgtgctg gccgtttccc gccaccacca ggacgacgac gtcaacgagc
      421 ggctgatgat gctgcgcacg ccggtggcct ccgtcgtcga cacctggcgc gcggaacgcg
      481 accggtggcc gggactgcgg atgaggctga tctgcgtgct ccagcacggc ggcgtcgccg
      541 acgcggccgg ggtcgccgcg tacctttcct gggccgcggc cctcggcgtc gaggaggtct
      601 gcttcaagga gctctacgtg tcgaccagca cggagtcgct ctacttcgac cgcgccgcca
      661 acgtctggag ccgggagcac caggtgccgc tggccgtcgt cacccgcttc gccgaggagc
      721 acggcttcga accggcgagc cgtctgccct ggggcgcgcc ggtctaccag ggcacctggg
      781 acgggcgccc gctgcgcgtc gccgcctaca ccgagcccag tctgctctgg gagcgcgcca
      841 acggcatcgc ccgcagctgg aacgtcatgg ccgacggccg ctgttacgcc tccctggagg
      901 accgggccag cgagatcgtg gcggaaggcg cgccggcatg aacttcgagg agttccaggc
      961 gttccggcag cggcagctct gcgcctcctc ggccctgctc gacgccgccg agaccaacct
     1021 gtaccgggcg ctcgccgcgc tgcgaccgga acaaccggcc gagatgaaca cggtgcaccg
     1081 gtgcgatctc gcccgcgcct ggctgcggcg ctacgcactg cctgaggagt ggtccggccg
     1141 tgcgatggtc tgccgagggg tccggcacgg gctcgccgtg gtgttccggc aactgcacgc
     1201 cgaaaaggcg cggttgtggc tgcccggcga tgtgtacccg gtctacttcg aactggcccg
     1261 cgccgcgggc ctggagccgg cgtcctaccc cacgctgccg gtaccggtcc tgcccggttc
     1321 accggcggac caccggcccg agtatctgct gctcgccaac ccgagcaggc cgctgggccg
     1381 ctacctgtcc gacgacgagt gcaccgcggt gatctcgtgg ctggaggcat cgccgcgccg
     1441 ccgcctgctg atcgacagcg tctacgacct cggcgccccg ttcgcccccg gaacccggcg
     1501 cctgctggac accggtcgcg ccgtcctgct gcactcggtc accaagggat ggctgtggcc
     1561 gcgcacgttc ggcatcgttg tcctggatcc tgcgcagacc gcatgggccg aggcgttccg
     1621 ggcggatccg ccgacgcccg cccaactgcg cctcgccgac cgtctgctga ccggacacgg
     1681 tgaggtgccc cggcagatcg tcgacgacct ggcggcacgc gccgagcggc tcttcgaccg
     1741 gttgccggac gacgtgctca cggcgatccc cgcggcgagc cggacctgcc ccggcaacta
     1801 cttcttcccg gtcgggatcc cggcggagac gctccggcgc gactacggcg tgctcgccat
     1861 cccggtcggt gtgttcgggg acagcgcctg gcccggctcc gtcctgacca gcctcggatg
     1921 acgtcaggcc aggcgcaggt cgatccaggg gacggtgtcg ccgtcgcgca gcagataccg
     1981 ctcgagctcc acgaagccgt gccggccggc gaagcgcagc ccgtcctggt tggaggccag
     2041 caccacggtc tcgatcacct gggcgtccag cgcacgggcc tggcccaggg cgcgttcgta
     2101 cagccgggtg ccgaggccgc ggcggcggtg ttcgggcagg acgcgggcga tgaccgtggc
     2161 cgtggcgccg ttgtcctcgg tgggcgggcg tacggtggtg cagccgatca ggacgtcgcc
     2221 gaggtgggcg acctccatac ggttgcggcc ggtgcgggca cggacgtcgt cgagtgacag
     2281 cacgtcgccg gggatgatca ggttgtggac gtgctgccag tcgtggatcg aggcgtcgtc
     2341 gtccacctct tggatgcgaa ggtcggtcac cggcccagcc aacagctgcc cgctgtcgtc
     2401 cgtcaaacgc aattgccgga ggaatcggtg cagttcagcc cgcaccggga gcgtcagcgg
     2461 ctcccgtcgg ggcgcggccg tcggggcgtg gcgcggagta cgtggggcgg ccggtggggg
     2521 agtgctagcg tcgccccatg cctgaactga tcgcacccgc ggcccggctt cggtcctcgt
     2581 ggctcgccgc gtgcgcggag tggcctcccg gtgcccatca ggacgggacg ggtctgcgcc
     2641 tggctcccga gggcgatctg cgcgaccccg acgtgttccg cacctgggtc gagcgactgc
     2701 gccggcagtc ggaccggtcg gtcgccgtgg gagagggccg cgtccacgcc acccactggt
     2761 ggatcgtgga ggacgacagc tatctcgggg ccatcgatgt gcggcactac ctgaacgccc
     2821 tgctgctcga cgtcggcggg cacatcggtt acagcgtccg cccttccgcc cgcaggcggg
     2881 gactggcgac ctgggccctc ggcgcggtgc ttccgcgggc ccgtgcgctc ggtctggacc
     2941 gggtcctcgt cacctgcgac gacgacaaca ccggttccgc acgcagcatc gagcgcaacg
     3001 gcggcgtcct ggaggacgtc cgcgctgccg gctccggcct caagaggcgg tactggatcg
     3061 acctgtagga agggtgaacc gccgtccccg cccgcgtcgc accgcgctcc gtgcgcgttc
     3121 cctggccagc tccctgaggt aggcccgtgc gtccacctgg atcgtgtgcc ggggcgaggc
     3181 cacgtaacgg cgggccgtcc gggcccggtg ggcgcggatc tcggcgagca tcccgtcccg
     3241 cccgggcagg gcgcaccggc cctgcaacag gtcggcgacc cagtgggact gggcctgcgc
     3301 cagcggcatg atcgcaccga gcggctggac gaggccgatg aagtacaggc cgggacggtc
     3361 gggggagacg acccggtggt agagaccggg atcgttgccg ctcacgtcga tcacctcgtc
     3421 gtcgaggaac gggaacgcga tgtcgtaccc cgtgcagcag atgatcgtgt cgatgtcctc
     3481 cacactgccg tcgtcgaacg ccacctgggt ggcgtcgatc cggcggggca cgggtttcac
     3541 cgtgatgtcg ccgtggccga gccgggagag caggtcgtcg gagatcgtgg gatgggcggc
     3601 gaggacgcgg tgttcgggtt cgggcaggcc gtagtccgcc agccgaccgc ggctgagccg
     3661 cagcagcagg tgcaggccgc ggtcctgcac ggccagcggc attcgggcca gccaggagtg
     3721 ggtgaggtgg tccgtgggcc tgccgaacag gtacttcggc aggatgtgcg cgccccggcg
     3781 catggccagg aacgtttgtc gggagacgcg ggagacctcc accgcgatgt cgcacgccga
     3841 gttgccgatg cccaggacga ggacgcgccg gtcggcgaag ggttcggggc tgcggtagtg
     3901 gtgcgagtgg atccgggtgc ccgcgaaccc tgcgacgccg gggatctccg gctcgggcca
     3961 acgcggtttc caatgatggc cgttggccac caggacggcg tcgtagaccc ccgtctcgag
     4021 ggcgccggtg tcgcggtggc gggaggtgac cgtccacctg tccccgtccg ggacgacccg
     4081 caccacctcg gtgcggaacc tgatcgaggg gcgcagcccg aagtgctcga cgaacgcgtc
     4141 gaagtagcgg gctatgtggg cgtgccccgg atacaccgga cagtcgtccg ccatcgggaa
     4201 tccggcgtac tccatgatct gacgtgaggt gttgatgtgg agcgagcggt aggccgacga
     4261 ctgtccgttg tcgttgaggt agcgccagtt gccgcccacc tgcgagccca actcgaagca
     4321 gtcgtaggcg atgcccctgt cggcgagaac ctggcaggcg gctatcccgg aagaaccggc
     4381 cccgatcaca cacacgttcc gcacgccggc ctccttgtga ccacccggtc atgtccccgg
     4441 tcgatcacag gctggacggc ccgccgcgcg ctgtcaatgc atgagccccg ttcaacaacc
     4501 atgtgcgcca agcccgttga catcagtgga cggccgctcc accatgaccg ggcggtcaca
     4561 tgaccgcccg gtcacacgga ggagcgccca tgcccacgcc cacctgggac cggctgtcac
     4621 cggcccgccg agagcgtgta ctcgtcgcgg ccatggacga gttcggcacc cacggctact
     4681 ccacgggcag cctgaacgtc atcgcccgcg aggccggtgt cgccaagggc tcactgttcc
     4741 agtacttctc cggcaagctc gatctcttcg cctacgtcgc cgagcagacg tccctgcgcg
     4801 tctacgccca catgcagccg tggctggacg gctacgacga gtccggcgac ttccgcacct
     4861 acctcgtcga cgcgctggag gcgtggctcg actacttcgc cggacagccg ctcgagcgcg
     4921 gggtgacggc cgccaccaac atggagatgg accccgcggt ccgtgacgcc gtccgggcgc
     4981 cggtgaacgc cgtctacctg gccggactgc ggcccctgct ggagcgcgcc gtcgccaccg
     5041 gggacctgcg caaggacgcc gacctcgacg cgctgctgtc gatcctcctc gtgttcctgc
     5101 cccacctcgc gctcctgccg cacctgtccg gcggcgacgg ccccctgccg ctcacctcgg
     5161 tcgacccgca ggcccggcgc gccaacctcg aacgcctcgt caccccgctg ctggccgact
     5221 tcacgcagga ggacgacgga tgagcggctt cgactacgac gtcctgatca tcggatcggg
     5281 cttcggcggc agcgtcagcg ccctgcgcct cacggagaag ggttaccgcg tcggcgtcct
     5341 ggaggccggg cggcgcttcg ccgacaccga actcccgcag acctcctggc gcctgcgccg
     5401 ctacctcttc gcgccgcgcc tgggatgcac cggcattctg cgcatgaccc tcctgggtga
     5461 cgtgctcgtc ctcagcggcg ccggcgtcgg cggcggatcc ctcggttacg ccaacaccct
     5521 gtacgaaccg ccggacgcgt tctacgaagg ctcgcactgg gcctccctca cggactggcg
     5581 ccgcgagctg gccccctact tcgcgcaggc ccgccggatg ctcggcgtca cgcccaaccc
     5641 gctggtctcc gaggccgacg tgctgctcag ggacaccgcc cgcgacctcg gctgcggcga
     5701 cacgttccgc accaccccgg tcggcgtcca cttcggtccg gccggtgccc tccccggcgc
     5761 cgaggtgccc gacccctact tcggaggtgc cggacccgcc cgcaacgcgt gcacccactg
     5821 cggcgcctgc atgaccgggt gccggcacaa cgcgaagaac accctgccca agaactacct
     5881 gggcctcgcc gaacgggccg gcgcccgcgt cctggaccgc cggaccgtga cgggcgtcga
     5941 acggcgcgcc ggcggctggg ccgtcacctc cgtccgtacc ggcgtgctcc cgggccgggg
     6001 gcggcagcgc ctgacgtccc ggcacgtagt cttcgcggcc ggcgcgctcg gcacccagcg
     6061 cctcctgcac accctgaagg acgacggcgg cctccccgac atctcacccc gcctgggacg
     6121 gctgacccgc accaactccg aggccgtcct cggagtccgc gccccgggac gcgacgcgga
     6181 ctactcccgc ggcgtcgcca tcacctcgtc cgtgcagctc gacgacacca cccatgtcga
     6241 gcccgtccgc tacggccgcg gcagcaacct cctcgccctg ctcggcgcga tgctcgtcga
     6301 cccggtgccc ggccgctccc gcctgcgcgt gggactcgcc gcgatggccc gcgacgtccg
     6361 ccggctgccc gccctgcaca acccccgccg gtggtcgcag cagaccgtgg tgctgctcgt
     6421 catgcagacg ctcgacaact cggtctccac ccgtctgcgg cgcacccgca ccggacggcg
     6481 ccggctcacc agccggctcg gcgaaggagc gcccaacccg acctggatcc ccgccggaca
     6541 ccgcgccgcc cgcaccaccg ccgaacgcgt cggaggccag gcctgtggca cctgggccga
     6601 cctgttcgac gtaccgacca ccgggcacct catcggcgga tgcacggtcg gagacagccc
     6661 gctcaccggc gtcatcgacc cctatcaccg cctgcacggc taccccggcc tgcacgtcgt
     6721 cgacggctcc accatctccg ccaacctcgg cgtcaacccc tcgctcacca tcaccgccct
     6781 cgccgagcgg gccgccgccc tgtggcccaa caagggcgag agcgacaccc gccccgaacc
     6841 cggccggccc taccgccacg tcgcacccgt ccccccgcgc cggccggccg tcccgaccac
     6901 cgccccgggc gccctgcgcc tccccccacc tcacggaacg gacgcgccat gaccgtctac
     6961 ccggatgagc cctggcatct tgccggacag atgtacgtgt ccctctggct cgtgccgcgc
     7021 gcggaacttc cccccgtcgc gcccggcacc cgccccttcc ggttcggcgg ccgcggcctg
     7081 gtcgctgcgg cctgggtcgt ctacgagaac gacagcgtcc tgcactacga cgagctgctg
     7141 agcgccgtgc tcgtccgcga cggcgcacgt ctccgcgtct gcatcaccga catctgggtc
     7201 gacagcgagg cctccatggc cggcggccgc gccctgtggg gcatccccaa ggagatggcc
     7261 accttcgagg tccggcgggc gcacggcgcc tccttcgtcg cgaagaccgg cgaagggaca
     7321 ctcgccaccg cccgcttcac cgcccggggc cgcctgcccg gccgtccgcc gctggcctac
     7381 cggctcgcac agtccctcga cggccggctc aagaccaccc gggtccgcag ccgcgccacc
     7441 ctgcgaccgg cgcgagccga atggaccgtg cccgacgaca gccgactcgc cgcgctcgtg
     7501 cgccgcgcgc cccttctcag cctcaccctg cgcgacttca ccctccgctt cggcggctga
     7561 acgtcccgcg cgcccccggc ggacggccac ggcggcccgt cgagtgcgca ccgcccgcgc
     7621 cacgctcacc gcctctcgca ccgcccgcgc cacgctcacc gcgtcacgca gcgcccgcgc
     7681 cacggttgcg gcgctcgcgc caccgcgccc cccgaccgct cggccgcgaa gccgccgcac
     7741 cggtcccctc gtccaccgcc ccgggctccc acgcaagccc gcagcggtgg ggcccgtccg
     7801 ccccgaaccg gacgacgccc cgcccctcac ggagacgtac caccaggaat cactgctcct
     7861 cctcacggaa aaggtgatct cgtgttccgt acactcctgc ggtccatgac cgcggtgctg
     7921 ctgaccgcgg cagccgccct caccctcgca ccgggcgccg aggcccaccc cgcctcgccg
     7981 acggtccggg cgacggaccc ctccaccgcc ggatcgttcc ccgtcgccta caccgacctg
     8041 accgtgtcgg ccgcgggccg ctcgtacagc gcgcgcgtct ggtacccggg cacgacggcc
     8101 ggggcgaacg cgcccgtcgc cgccggcgcc catcccggcc tcgccttcgg gcacggcttc
     8161 ttccaggcca tcacccagta cgagagcctg ctcaagcact acgcctcctg gggcgtgatc
     8221 accgtcgccc ccaagtccca gggcggcctg ttccccagtc attccgcgtt cgccgacgac
     8281 ctcaacgcgg ctctgacctg gctcaccacg cagaacacca ccagcggctc acgcttcgcg
     8341 gaccgggtcg acaccgggaa actcgccctc tccgggcact cgatgggcgg cggcgcggcc
     8401 ctggtcgccg ccggccgcaa cccggccgtc aagtccgtca ccaccctcgc cgccgccgag
     8461 accaacccgt cggccgtcgc cgcctccgcc accctgggca ttcccgtcca gtacgtcggc
     8521 ggcagcgccg actccatcgc cggtgtcgcc gccaaccagc agaagatgta cgacgccaag
     8581 ccgtcacaca cccagctgcg ggtcatcacc ggcggcttcc actgcgggtt cgaggacagc
     8641 tccggcatcg gctgcgacag cggcaccgtc acccgcgccg tccagctgaa actgacctac
     8701 ggcgtcacga cctcctggct gctccacacg ctcggagccg acacctccct ctacgaccag
     8761 gtgtggggct ccgccgccca gaacctgccc ggcgtcgtgt actccgccaa gccctgaccg
     8821 gtcccgccga ccggtgacgg cggcccgccg accgccgcac tccacgccca gcacgcctgc
     8881 gggcggccac gtgaaccccg tggccgcccg cactcctttg ccccggcgac cggctccaca
     8941 cccgaccccg catcggatct cccacgcccg tgacctcgca cgacccgccg cacgccccgg
     9001 cccggacgac cgcaccggag cctccttgca aggtctacgg cgagcgtggc aacagcgtgc
     9061 gggcaaggac ccggcaggaa ggcggcccca cactcgtcgg catcggcctc atcagcaatg
     9121 gtcggcttcg gcatgcgggg ccggcggaga gtgggtagga catgacggag ttccccgcgg
     9181 ccgctgccac cgcggacgcc ggccgcgtcg gggtcatgga gtcaccccgg atcgagctgc
     9241 gcagcgacat caccgtcgag ctcgtcgaca gcagcgcgag cgatctcgcc gtcgtcaagg
     9301 cggctcgggt gtccaccgcc ggtgaagacg ccaacgacga gctgtacgac ggcggttcga
     9361 cgcgcggact gatccgctac ctcatgcgca gccgtcacgg cagccccttc gagcacaact
     9421 ccatgacgtt cctggtacgc gctccgatct tcaccgtgcg ccacctcatg cgccaccgga
     9481 cctggtcctt caacgaggag agcgcccggt accgcgaggt cggcgccgcg ttctacgtgc
     9541 ccgacgccac ccgactgctg cgccaggagg gcaagcccgg cgactaccgg tacgtcggcg
     9601 gcagcaccga cgaccaccag caggtggtcc ggtccgccac ccgggcctac gaggtcgcct
     9661 tcgaggagta ccagcggctg ctggacagcg gcatcgcgcg ggagatcgcg cgcctggtgc
     9721 tccccgtctc gacctacagc gtgctgtacg ccacctgcaa cgcgcgggcg ctcatgcact
     9781 tcctcagcct gcgcacccac cggcccgacg cggcctacgt ctcccacccc cagcgggaga
     9841 tcgagatggt cgccgaacag atggagacgg cctgggcgaa gctcatgccg gtcacccacg
     9901 aggcgttcac cgccttcggc cgcgtcagcc cgtgacgcgg cctcgtcccc ttccccaggg
     9961 ggccggacct gccggtcccc gtcccctcct ggaggacttt gtgctcgaag tcaacggtgg
    10021 caagcggatc gccggatcgg tccgcacctc cggtttcaag cactccctgg tcacgtcggc
    10081 agccgccgct gtcgcggcgg acgccgacgt ggtcctcgac aactgcccgg acatcgtgga
    10141 gacggacgtg ctctcacgcg tcttcacgac actcggcggc cgcgcgcggt acgccgaggg
    10201 caccctgacc ctcaacggct ccgggatcga gcacaacgtg ctcccggccg acctcgtcag
    10261 ttcgatccac ggctccctct acctcgtgcc cggtctggtg gcccgcctgg gatccgtcca
    10321 tctgcccgcc agcggcggct gccgcatcgg cgagggcccc aagggacgtc cggtgcgcca
    10381 tgtcctggac gtcatggaac gcttcggcgc gaccggcggg acgaccgccg agggcggact
    10441 gaaggtcagg gccgcacggc tgacgggctg tgagatcgac ctgctcgact acacccgcaa
    10501 ccgggcgctc atgagcggtc cgctctacgg gggagccacc aagaccgccc tgctcaccgc
    10561 cgcggcggcc gaaggcgtca ccaccttgca ccacctctat cccaagccgg acgtcgtcgc
    10621 gctcatcgac gtcctgcggg agctgggcac cgacatgacg tggaccggcc cggagaccct
    10681 ggtcatccgc ggcagcggca tcggcgcgct gcgccgggac gtccgctaca ccctgccgcc
    10741 ggacctgatc gaggtcgtca cctggatctg cgcggccgtg accgtgggcg acgggccggt
    10801 gcacatcacg ggccccggca tggaccgggc ggtggcggcg ctggcacccg agttcgacgt
    10861 gctgcgccgg atgggcgtgg tgaccgacca cgaggcggac tcggtcacgg cccacccggc
    10921 cgaacggccc ctggctcccg tcgaggtcct cgccgcctcc cggggcgtgt tcagcgacag
    10981 ccagcccttc ttcgcgctga tggccgggtg ggccgagggg gcgacgctca tcagcgaggc
    11041 cgtgtgggag caccgctacg gctacgtccc gggtctgacc gccctcggca tggacgccgt
    11101 ccaggacgac tacgcgctga gggtcgacgg cgtcaggacc ccgcaccgga cgggccagga
    11161 cctcacggcg accgacctgc gggcggccgc ggtgctgctg ctggccgcgc tcgcggtgcc
    11221 gggacggacc gtgctgcgca acacgcacca cctcgaccgc ggataccgcg acatcgtggg
    11281 cgacctgcgg tcgctgggcg cggacgtcac cccggcggcc gacccggccg ccggctgaga
    11341 gggcccgtca ggcgtgtgtg gcaggcccgc gaacgggcct gccacacacg ccgtcacgcg
    11401 cgggaaccgt cgtgggtgcg gcccgcgggc ggcagcgaac gcagccagcg cctggcctgc
    11461 gcggccgtcc gcagacggac cacgggaacg tcgggatgcc gggcgaacca ggcggcggtc
    11521 tcggcccgtc gcgtgccgtg ccgggaccag gcccagcgca ccgggtggcg gggggagaac
    11581 agcagcgcgc gccaggtctc ggtgttgtcg tgccacaggg ggcggcgcag cagcacgcgc
    11641 gagagcgacc tgcggatcac ccggtgcatc accgtgtgcc ggggcaggtc cagccagacg
    11701 aacagctgcg tcctggccgc cagcaggtcg ccgacgatcc agtggtactg ggcgtcgcag
    11761 acccaggcct ccgacgcggt gaaccgggcc acgtcgtcgg tgaactccgc tctgcgcgac
    11821 cagtgcgggc cgtggtacag ggcgtccatc tcgatgtggg ggatgccgag ccgctgtgag
    11881 agggctgcgg cgagcgaggt cttcccggcg ccggatatgc cggcgatcag gatcctgcgc
    11941 gggtctgcgg gctcggtcat gcgggggtgt ctccttcacc gcgtcgcggt acgagggcgg
    12001 tcagcgcggc cgtcgccgcg ccgagcgcga cgagcgtcag ccacaggacg gcgttgcccg
    12061 cggtgagcag gaaggcgccc acggcggggg cgagcacggc ggcggcaccc caggccagct
    12121 ggaaggtcgc gctgtagcgg cccttgtact cctcgggcgc cgccgcgttg gccaggacgg
    12181 tcatcacggg tgcgaacagg gcatccgcca cggcgccggc caccgcggct cccaggacca
    12241 cgggaacggc ccaccccggc gtcagccggc cggcgggcgc cagcagcagg aaggcgacgg
    12301 cgaagaccag gcaggcgagc cgcagcggac gcagcgccga gccgtgccct ccgaagcggc
    12361 gcaccgcctg cttctgggcg agcagcagcg ccacggaact ggtgatgagc gcggccgcgg
    12421 gcagccagga cggtccgtgc aggacgtcga gggccaccag cggcagcatc accgtgaggc
    12481 tgtccgtcat cagcgcgaac gccagctgtg tcaggcacag caggaggaag gggcggtcgg
    12541 cgagggtgcg gcgccaggcc ggacccgtcg ccttcggtgc cggccgggac gcggccgggg
    12601 cgccggtgcg gcggggcacg cgcacgccca gcatcagcag ggccgcggcg aggaaggtcg
    12661 ccccgttcag ccaggcgatc agatggaggc ggccggggtg ctggaggagc gcggcgctca
    12721 ggacggcggc cagtccggcg cccgtcatcc agcccgcggt gcgcagcatg ttctgggtgg
    12781 cgaggacggg caggagtccg tccttgccga cgacctgttc gagggccggg gtgttcgccg
    12841 tccagaacag gcgctcgcac gccgcgagca cggcggccag ggcgatgagc tggcccacgg
    12901 acgtgatcag cggatagacc aggaagacgg cgccgcgcag cacgttgctg agctggacga
    12961 gcgggagggc gccccagcgg tcgaccagcg tgccggcgag ggggccggtc agcaggccga
    13021 tcaggccgcc cgcggtgagc gccgcgcccg tcacgtccag cggtatgtgc tgcgcgcggg
    13081 tgaagaagat cagcgccagg ggcgtccaca ggccgttgcc gaccgcgtcg gcgaacagcg
    13141 ccgccaggta ccaccgtcgg gcgtgggggc ggtgtgcggg cgggcgctgt cccggccggg
    13201 tggaggcgag gtgcacggtg gcgtccaagg ggtcggtggt gaagccgacc ggtggccggc
    13261 gcggaggagg tggcgtccgc ggagtgcgct gtgccccggg cggggtccgt tgcgagccgg
    13321 gcgggacgcc gcgggtacgg cgccccgtct acggtgtgtc atgagttctt ggcggtgccg
    13381 gtcatgggct caccgtggtg ccggtgcgcc gtccggtgag caggtgctcg cggaccgcgt
    13441 gggggatgcg tccgtcggcg atccgtgccg tcgccacccc ggcccgcacc gcctggctgc
    13501 acgcctggac cttggggatc attccgccgg tcagccgggg cagcagcgcg tccgcctcgg
    13561 ccgccgtcag ccggtcgagc acctcgcccc ggtccggctg cccggggtag aggcccgcca
    13621 cgtcggtgag cagcagcagg gtgtccgcgc gcagggccgc cgcgagcgcc gccgcggcga
    13681 ggtcggcgtt gacgttgcgg acgccgctgc cgtcggcgga gcgcgcgatg ctggagacga
    13741 ccgggaccag gccggcgtcc agcagcgtcc gcagcagccg gtcgtccacg tcgacgatgt
    13801 cgccgacgag gccgaggtcg acccgctgcc cgccgtggaa cacctgccgg tcggcggccg
    13861 tgaaggtgcg ggcgtcctcg ccggtgaggc cgacggccag ccggcgctcc cggttgagca
    13921 ggccgaccag ccggcgttgc acctggccgg acaggaccat gcggacgacc tccatggtgg
    13981 gcggggtggt gaccctgagc ccgtgccgga agaccggctg gatgccgagc cgctccagat
    14041 gggtgtcgat ctgcgggccg ccgccgtgga cgacgacgac ccgtgttccg gcgtcggcca
    14101 gctcggcgac gtcctcggcg aaggtgcggc cggcgtcgcc ctcgtcgagg acggagccgc
    14161 cgcacttgat cagcacggtc cggcccgcga ggggccgtgc gggtgctgcc ggtgcggtgc
    14221 tcacccggtg gccgcgccgc cgcgctggta gaggacgccc tcgctccaga cccggtcgac
    14281 cttgccccag gccatggccg aggcggcgtc cgggaagaag ccgctgccgt tgaggttggc
    14341 gctggtgttg cacagcaccg ggactccgct cacacggtgg taggcggtga ggatgtcgga
    14401 gagcagcgcg tcgtcgtccg gactcacggt ctgaaggcgt gccgtgccgt ccaggtgcac
    14461 gaccgcgggg atccgtgagg tccagccggg ccgtacggcg tggtcgtaca gcatgtgggg
    14521 gtcgggcgtg cccgggtcga agatctccgg tgcctcctcg acgaggcaga tgggtgcgac
    14581 ggggcggtag tactcacggc ccttgacctg gttgagggtc tccttcatgg cggcgtcggt
    14641 ggccgcggcg aggatgctgc ggccgcccag ggcgcggggg cccagttcgg cccgtccgtg
    14701 cagcaccacg accggctcct gcccggtgtg cagcacccgg gcgagttcgt cgggcgagca
    14761 ggggcgggcg gtccagccct gcggtgtccc ggtggtgggg gtcagcgccg ggcccagccg
    14821 ggtgtgccac tccagcgcgg ggacggcgtt ccggccgccg atcgcgccga gcacggccgc
    14881 gccgatcgcg gatcccgcgt cgttggggaa gggcgggacc cacatccgcc gtaccagggg
    14941 cagggcgcgc agcgcgctgt tccacttgat gttcagcgcg caaccgcccg cgaagcacag
    15001 gttccacggg ccgtcgccct tccaggcccg gatcctcgcg tccagccgtt cgaggagcag
    15061 gttctggagg aactcgtgca cgctggccag gacgtcctcg tcggacacgg cgaagggctg
    15121 cacctgttcg cgtacggcgc ggaagaagtc gtgcagcggc ggcatggagg gctcgaagag
    15181 gctgccgaag cctccgacgg tccgggagtg ctccgcggcc gccggggacg cctcgttctc
    15241 gtagtggtcg tggaagaccg aggccagtac ctcgagcacc gcttcgctgg gcttgcccag
    15301 ggcgatgtac gccatcagct tcccggcgac cgacaggtcg tcgacgttgg cggactgacg
    15361 gtcccggcgg aacgggccga agtgatggcc ggcggtggcg taggtgtgac cgatcagggg
    15421 gaagagggat ccgccgttct ccacgccggc ctcggggtcc acccagtaca ggcgcgggaa
    15481 catgccgccg tcccagacga gcacgaaggc gggttcgccg cgccgcgcga actcgctggt
    15541 gcagtaggtg ctcagcacgt gtcccgcggc gtgcgtgtgg ctggtgtacg ggtaggggac
    15601 gccgtcgacg gtgaaggtgc cggacaccga cggacgcagc aggtcggggg aggtccgcga
    15661 ttcgcggtac gggccgacga cgagttccag cggctgtccg cggtcggccg tgtccaccgt
    15721 cccgctctcg tcgccgtccc agccgtcgac gacgaaggcg tcgacgtcct ccatgcggta
    15781 cccgtgctcg gcgaggatcg tgggcacgat gcccaggtcg ccgatggcgc tgtagcgcgg
    15841 gttgttggcg agtttctcca tctccacgct caggacgagg cgccggtcgt cgaccagcgc
    15901 gacagcaccg tcgtgagtca gtttcaggcc acaggtgatc atgagcgttc agctccttgc
    15961 cgaggcgggg tgaaggcggg gggcgcggtg cgcggggcga cggggcgccg gtacaggtgc
    16021 gatccgcggc ccggggggag caggtcggcc catacggcgg gcatgtgctg gggttcggtg
    16081 cgggtgaagc cgtgccggac gaaccaccgg ccgctgtgtt tggaggccgc caggaggaag
    16141 cggcagccgc ccagggcggc cagggcgtcc gcgcgctcca ccatccggcc tccgatgccg
    16201 agcccttggc ggtcggcggc gacgcagagg ttgtacagca gcaggtcgtc cccgagccgg
    16261 gtcaggccga cgcaaccgat gacgcgcgag tcgtgcacgg cggtcaggta gtcgccgatc
    16321 cggttgcgga actgcgtacc gctgcgggcg acgagcaggt cgtcggcgac gaagggctcg
    16381 gagagccggg cgatgccggg tgcgtccgtg gccagcgccg ggcgtacgac gacgtcctca
    16441 cgcatggcgc cgggcgaagc cgagcccgaa cggctggtcg gtgggcatga tctcgatcat
    16501 gttgacgttg acgtgcgggg gccgcgacag gcaccacagg acggcgtcgg cgacgtcgtc
    16561 cggggacagc gggctcactc cgtcgtagag gcggtcggcc cgctcctggt cgccgtcgta
    16621 gcgcacgagg gcgaactcgg tgcgggccat gccgggcgcg acgcagctga cccggacgcc
    16681 ggtgccctcc aggtcggtgc gcatgctcag gctgagctgg tgcacgaacg ccttggtcgc
    16741 cgcgtacacg ttgccgcccg cgtaggggta acgcgccgcg atggagccga tgttgacgat
    16801 gtgaccgcgt ccgccggcga tgagccgggg gagcagcagc gtcgtggtgt gcagcagtcc
    16861 gctcacgttg gtgtcgacca tcctgcgcca gtcgtccacc ttcgccgact gcaccgggcc
    16921 gaaaccgctg gagaggcccg cgttgttgac caggcccacc accggggggc agtggggaag
    16981 atgctcgtcg agcgcgcgtt ccagcgcgtc caggtccgtc acgtccgcca ccgcgggcag
    17041 cacccggccc ggcccttccc cgtcggcgag ttccgccagc cggtcggcgc ggcgggcgac
    17101 cgcgatcacc gtgtgccctt gcgcggcgag ccggcgcgcg gtgacgcggc cgaagcccga
    17161 cgacgccccg gagaccacga cggtccccag ttcctgactg ctcacgtgcc ccacctcatg
    17221 caatcgtcat ctgtgcgtgc cctgctgccg ggtgacggca tgtcacatgg ggtcgtagct
    17281 catcagcagc atgtcgcggg tgccctcgcc cagcgaggga tcggcgaccg agacgtccgc
    17341 gaccccgtgc cggacgcggg ggtcgtcgcc gaagaaggag tcgaggcagt cggtgaagac
    17401 cttctcggtg atcagctcgt gctccggtgt gtacacgctg gtcctgccgc cgctgatgtt
    17461 gtgccggttg accatgtgca ggctgacgta ggtgcagccg tcgcggtgga cgccctcggg
    17521 ggtgggccgc ccctgcgcgt cgtcgcgggc gacgatgcgc acgcagtgca cctgcacggc
    17581 ccactgctcc acctcgggca gcggcaggcg gccgacgttg aagtcgatga gcgcggtcag
    17641 gaaggcgccc tcgcggacct cgtcggtcag ctcctcgtac ttgcgccact gtccgccggc
    17701 gaaggcgttg ttctcgacgg tctggaagta gcccgggttg tcggcgacca gcagttcacc
    17761 ggtggcgggg cgccaggtgt agcgggtgtg ccgccggtag cggtagttgc ccccgtccgg
    17821 caggtacggg tcggccggca ggtcgtcgta ggaggccgcg agggtcttga ggctgtcctg
    17881 gagggcggcg ggtacccgca tgtcgctgcc ggggaccatg gagaagccgg tgcggacgag
    17941 gtctccggtg atgtcggccg ggctggacag ggcggccgtg ggtcgggtga gcacgggagg
    18001 ttcctttctt ccgccgagag gcgggctgtt ccgtggcggg ctggggtcgg tcaggtgcgg
    18061 gcgaagtgga cgagcagcgc ccgccggtcg tcggggcagc cctcggacac cggggggacg
    18121 ccgtgccagg agtcgtcgga gcgaaccagc accaccgacg tgccgagcag cggcaggacc
    18181 cgccgggcga cgtccttcat gtccggcccg cgcagcacgt gcaggtcgcc ctgccactcg
    18241 ctgcgccagg tgtcgttgaa gtagaagaga tgggtgaccg ccttgtcggg gcggtcggtg
    18301 tgcggctgga tccagcagcc gctggagtac cgcgtcatgc gggcctcgac ggtgcagccg
    18361 tccaggtcgg cgccggtcag ctcgacgagg gcgtcccggt agtcgtcgga ggtcacctcg
    18421 tcgaccagca ggcgccaggc ctcgggcagg gtgtccacgg cctcgcggtg ctgccggccc
    18481 tcgctcacga gggtccggtt gtgcatcagg tagtgcttgc cccggccgct tcccggccgc
    18541 cgttcgctgc gcacgaaccc gtcggcggcg aacccgtcgt tcagcgtgcg cgccgtgtcg
    18601 tcgtcgcgga aggagctcgg gacgaccgcg tagtggtagg ggtccttctc gagccgcgcg
    18661 tcgcgcaggg cctgaaggtc aatcagcgtc atgtcgttct ctcctcgggg cgtggtgctc
    18721 gaagacccgc cgcaccgccc gcagccgggt cttcggggac agcccgtgct gccgctccag
    18781 gtagcgggcg acgctctcgt gttcgtcctc gatgccggtg atcaggctgc gcatcgtcca
    18841 agcgggggac gcggtacgga tctggagctc ctccagggac ccttcgtagg accactgggg
    18901 gcgcgggtcc tgcggcccca gcgcccggta ggcgcggccg gtgaggctgt agtcgcccgc
    18961 cacggccgcc agccgtaccc cgaggccgcg cagggtcagc gcgctgacca cccccgtgcg
    19021 gtccttgccg accgtgcagc agacgtagac ggggtcctgg tccggctcgg ccagcaggcc
    19081 gatgatctcc acggccaccg gggcggcgag ggtcagcatc gagcggtagt tgaacaggta
    19141 ggcgctgggc ggcgggcggc gcacaccgcg gatgcgggac atgttcccgc ccacgggccg
    19201 gcgcaggagc cgggcgcgca tgccggccgg tccgtcctcg atgccctgct cgaaggcggt
    19261 gcgcaggtcg acgacggtgc ggatgcccag gtcgtccagc gcgggcgccg tgagcgggga
    19321 gggggccggc ccccggtaga gcacgccgga ccgcagccgc gcgccgtccg ggccgggcag
    19381 cccggcgctg tcgcggacgt tgggcaggcc gggcagcgcg acggtgcgcg agccacgggt
    19441 gggacgggcc gccgccgcgg gagttcgctc ggcggggtgt cggcgggctc cggtggtcac
    19501 cgtgccaccg cctgttcgcg ccgcagcagc aggtcggtga cgcggtccgc ggtgctccgg
    19561 tcggtgaccc cgatgcgcac cgcggccggg ctgtcggggg tgctgggcac ggcgcgcacg
    19621 acgtagccgt gcgcgtggag gtgggccgcc gcgtccgccg cctcgcgcgg cgaggcgacc
    19681 tgccaggtgg cgaagttgcc gccgcccggg agggcacgcc agccgggcag cgcctcttcg
    19741 acaccgcggg agaagtgttc cctgacctcg cggacccccg cccagatctc ctcgaacagg
    19801 ggctgctcgc gcagacaggc ccgcaggagg gcgacggcgg tgccggacac cggcccctcc
    19861 gggtcgaggt cgagcagggg ccggacggtg tccgggtgcg agctgagcac ggcgatgcgg
    19921 gcgccggaca ggccgaagca cttggagaag gtgttcaccc gcaccacatg gggcgggtgg
    19981 gggcgcccgg tcagcgtccc gatctccttc tccccgcctt cggtgaaggc gaggtaggcg
    20041 gtgtcgagga cgagcaggct gccgtggtcg gcgacagcgc gggcgagaga ctccagctcc
    20101 gcccgggcgt ggacctggcc ggtgaagctg tgcggctggg tgaccacgac gaaggcgggc
    20161 ggaccgccgc gcagccgggc ggccaggtcg gcgagggaga accggccggt gccggggtcg
    20221 ggcggcacct ggtcgagccg gcacccggcg atccgcgcga atttctgcca gccctcgtag
    20281 ttcgggtggt gcaggacgat gcgccgggct cggggaaagg cccgcaccag cagccccagg
    20341 cccgggtcgc tgcccgcggt cagcaccagc ccgtccgggt ccgcgtccag gtggtcggcg
    20401 atctcggcgt agacgtcgcg cagcaccggg taggtcagga cctccagggg gtccagaccg
    20461 gcgagcgtgc gccggtgcag gtccgcggcg cgcgcgtcga gcagaccgct gctcttgagg
    20521 ttgacctcgc cgggccggcg ggtgcgacgg ctgcggtagc ggccgctgct ctcgacccgg
    20581 aagggggacg gcgctcccgc ctgcgcgggc tcctcctcgc gcggcgggta cgcactcacg
    20641 atgcccccag cagcaccggg tcgccgtccg cgccggccgc gcgggcgggg atccgctcga
    20701 agacggcggt cacgtcgggc tgcgggccga agaccacttc gtaggcatcc cgcagctggg
    20761 ccgggtccag gtcgtgggta ccgggcacga acagctgccg gttgaaggcg gccatctcct
    20821 cgtccgacag gtcggggcgg gccgcctccc agggcgcgta gacggtggga cgggcccgcc
    20881 cgccgagcgc ctggacggtc gcgatggtgt gccgcacccc ctccacgctg gtgcccggca
    20941 gtcccacgat cacgaagcag ttcagctcga tgccggcctg cgcgcaccag ccggcgagat
    21001 tctccaggtc ctgctgcgac ttgtgcttgg agcggggcag ggcgccgtgg ccgtgcgggt
    21061 cgagggtctc cagaccgacg ctgatccgga cgcagcccgc ccggcccatg gcccgcacga
    21121 ggtcctcgtc caggtggtgc atcgtcgtcg cgcacttcca ggggaagcgt gccccgtcgg
    21181 cggtgagccg ttcgcacagg tccatggtcc agcggcggtc cagggtgaac gtgggcgcgt
    21241 agaaggcgac gtactcgaag gacgcggtgc ggaaggactg ttcgatgtac tcgacggtcc
    21301 gctccacggt gagccggcgt tccttgcggc cgaagatggg gtggacctcg cagtacgagc
    21361 agccgatggg gcagccgcgg gcggccggga cgacgagttc gcggcgctgc gggatgccgc
    21421 agaacttgtt ggcgtcgtcg tggtagagct cgtcgtagcg ctggtagggg atctcgtccg
    21481 gggtcggcag gtaccactcc tgcgcgggca gcacggcgcc cggcgaggac ggcgcgtgcc
    21541 agctgccgtc ggcgtgccgc aggtgcacgc ccggcgccgt gacggtctcg ccgtcgaaga
    21601 accgcagggc cgccaggacc gcggcctcga agtcgccgtt ctcggcgacg gcgtcgatgt
    21661 cgagctgctg gaagaacagc gggttgacgc cgctcaggcg gccgaaggtg acgatcgggg
    21721 tcccggggct cagtgcccgg gcgtagctga cgaagcgccg caggccgtcg atgccgtcga
    21781 agtcgttcat gacggcgatg gcgtcgtagc gctgctggaa gaggtcgttg ccgatgtcct
    21841 tccaggtccg gcgcagcacg gtggcgtcca ggacggtgac ctcgctgtcc ggcagcgcgg
    21901 tgcgcaggtg accggccacc tggtagaggg cgaggtggtg gcccgcgttg aagtagctga
    21961 ggatctgcgg gggccacacg accaggatgc gcgaccccgg tgcgagggcg gccgcccggc
    22021 cggcgggcgt gacgtgctca gacatggagg gccctttcgc gggtgtccgg gcggacacgg
    22081 tggacggact tgaagcggtc gggcacggga ttgcgcctgt cctgccagac gacggcggat
    22141 tcccaccagg tctcgacggc gaggagttcg gccgcggtgt cgggtccggt cagcgagacg
    22201 acgatctcgg cgacggacga gccgagggag gtggcggggt cgtagtggcg cccctcctca
    22261 ccggtcgcgg tgtacaagag ggtctgcggc agggggcttc gccgcggcag gtggcgcagc
    22321 accccgtggg cggaagggaa acgcgcgtag ccctggcgtc gtccggtcgg acggatcgtc
    22381 acctggtcgc tgcgcccggc ctggccgagc aggctcgcgc cgtgcagatg gacgccgagg
    22441 gtgtcctcgt gcgtctcgac catgcgtgat ccgcctgccc ggcaggcggt ctcgcagacg
    22501 acgagccggt cgtccggggt gtggaagaac tcgacctgga aggcgcagac gccgggcacg
    22561 gccggcatgg tggccaccac cttggccgcg gtgtcgcgca gccgggcgga catcgggtcc
    22621 tcgtccggca tcatgccact catcccgggg gcgtcgtacg ccacggagaa ccagtcggag
    22681 tagggctggt aggacggttg ggccaggagg atccgcccgt cccgcatcag gccgttgatg
    22741 tggtagaagt caccctccac ccaggcctcg gcgaggtcgg gtgcggcggt gcggcccgcc
    22801 gcccagtcgt cggtgaacgc cgtcagcgcg tcgccgtccc acagcaccct ggtgccgttc
    22861 gaaccgcctg acaggcggct cttgacgacc agcgggaatc ccgcctcgtc cgcgaaggcg
    22921 tccaggtcgg cgggcgaggc cagccggcgc atcggggcga ccgggatgcc ggcctcggtg
    22981 agcaggctct tcatcgtgta cttgtcgcgg tacgcggtgg cgcaggccac gtcctggccg
    23041 ggcagaccga ggcgctcgcg cagcgtagcg gcgggcagca cctcgcgctc cccggtggac
    23101 agcacgcgcc gcacgccgaa gcgccggcac agggcgacca ggtcctcctc cagcccgggc
    23161 cggtcgaggc tgctcacgag gtgcagatgg cggaagccgc gcgcgagctc ggggaaggcg
    23221 ctggtaccca gtccgctgcg cgtgctgacc acgatcagct cctgccgggc ctgcgggaac
    23281 cactccggca cgcggtgcag gatcggcttg ttgttcagga ggagaaacac ggaagttcct
    23341 ttcgcctgcg ggggccgctt caggcgtggc cgtcgcgcag tgcctgtgcg tacgtctcca
    23401 gggcggcgga ccagtgggcg gcgtactcac ggaccgcggt gaggaactcc tcggcctgct
    23461 cccggtccgc caccagtcgc gtcatgccgg tgtcctcgtc gctgacctgg gccgcgtgca
    23521 tggtctcggc cttgatgtgg gagtccaccc aggcgaggtc gtcgcggccg gcgaacaggg
    23581 tggtcccggg tacctcgacc ttggcgtaca gacgacggaa gccgacggcg atgtccaggg
    23641 cgatgtcctc caccacgcgc aactgcaccg ccgcgcccag cggatgggtg gccagccggt
    23701 ccatggagtc cagcaggccg gtgacggcgc gggggagtac cgccgccgac tgccggtcct
    23761 cctcggcgac atgggcggcg acgggcttca ggacggtgtc ctcccaccag acgtagtgga
    23821 tgccggccgg gccgcgcgga gccacctcgc ggaaagcggg cgccgcgttg tccaggtcgt
    23881 cgccgatgac ctggtagacg gtctggaagg cggccagcag ctcgtggtcg ggggcgtcct
    23941 ggccctggaa gcggcgggcc atgacgccca gaccggagag cgtcgtgaac atgaacgcct
    24001 tggtcatggc acgccaccgg tgggcgatgg cgagcgcggc ttcgggggtg acgctctcgg
    24061 ccttgcgggc ctcgccgaag aaggcgttgt cggcccgccg cagccgtgcg gcgtcgatct
    24121 ccttccccac gcgcgcgtcg aggtcttgtt gttccgcggc ggacagggcc aaagcgttca
    24181 cggtcacaca ctccaaaggg gacggggccg gggcgggccg gaccggcggt gccgccggtc
    24241 agacgcccag gcgctccttg acgtcggcga agaaggcgat gtgccggtag tcgcgcgcct
    24301 gcgcgtcgta gtcggtgtac gagttggtga aggcgagcat gcgggcggtc acggaggtga
    24361 cgggctcctc gtggatccgg ctctccatgc gctggatctc accgaggaac tcccgcagga
    24421 cggcgacgat gtcggacgcg acgtggatga cgccgtcctt caccttcagg ccgccgtggc
    24481 tctcgcagta gttgaagaga agttgcgagg cgacggcgtc gtagttgggc cgggggatgc
    24541 cttccacggc gtaccgcagc aggcgttcgg cgaggatgaa ctgggctgcc tgccgggcct
    24601 gttgccgggg cagcttctcg tcgtcctcgc aggcgaggat gccggagacg tcgacgcgca
    24661 gctcttcgag gcctgccagc ggcttgcgct tcttggccga caggtactgc ggcacgggca
    24721 tgtcgccctg ccggtggtgg tactcgtgga gccgcaccca ccacgaggac gcctgctcca
    24781 cctgctcgtc ggtcatgccg tgcagcaggg ggaagctgtc cggcgccgtc acggcctcga
    24841 tcatgcgccg ggtgatgcgc agatggcgct cgacgaactt gtcgatgaag tagaagatca
    24901 tgtcgtccgg gccctggtgg ccgtcgagct ggttctccgg gaacagcgcg acgacgaccc
    24961 gcgccccgaa cccctcgctg gcgccggtga tgttgaccgg cagggtgttg ctcgcgtacc
    25021 gctcggccag gtgcgggtcg gtcggcaggg tctcgtacgt caggtagtcc agcgagagcg
    25081 acgggaagta ggacgcgtcg aagagggaga agacgtcgtt gtcccgtcgg ctgttgatgt
    25141 gttccttggt ggcctccagc acctgtccgg gccggaagac gcgcaggtcc gcggcgagcg
    25201 cccgggttat cgggcgctcg ctcagggcgg gtgaccgctc cagccggtcg gccagctcct
    25261 tcaggaactg cgggtcccgc aaggacgtac ggtcgccgat ccgccgtcgt agccggtcga
    25321 cctcggcgaa caccgggttc atgtcgtcca tcagttctcc tgcggccggg tgctcagtcg
    25381 gtgctgtagc ggtcgacgtg ctcgaaccag tactccagct gcacggtgag ccgggtgatc
    25441 tcctctccgg aatcgacccg ggacacggcg tgccacgact tgtcggtggg cgggaaggcc
    25501 agcagctggc cggggcgcgg gggcagccgg aagacgtggt cgtcgtcggg gtcgccgctg
    25561 aagtggacct cgaactcacc gccggcgttc gtcggccatt cggggttgag gtagaggatg
    25621 gcggtgatgg ccttgtcggc cttgtccttg tggacggaga tgaagtcccc gtccacgtgc
    25681 gtgtacacgc cgatgtcctg cgagagcccg tgcaggtcga tgccggtgct ctcggagagc
    25741 cagtcggtga actccacccc cgccaggtcg tccagcaagg agcgccagac ggccggcagc
    25801 tcgccggagg ccctgctccg ctggttgttg accatgaggt agaacaggtt catcttgtac
    25861 tgcttctcgt gttccggatc gacgcgggag atcgcggccg tccggttgac cggcgccgtc
    25921 gcgtacaggt cgctcaccac gtccttggtg agcagcccct gggccaggtg cagcgtgaag
    25981 ggggcgtcga cgtgcaggac cggtgtgtcc ttccgaagca tgaggtcagc tccttctttc
    26041 gggcatcgag tagcccagtg cgagggtgag cagagaaccg ggggcgtcct gggcgacggg
    26101 cgagaccgag tgccaggagg cgtccgaggg gacgacggtg tagaggctgc ccggtaccgg
    26161 cagcaccgag cgggcggggg cgtccctgtc gggcgactcc cacaggtcgt aggtgcctcc
    26221 gccgttctcg ggccagtgct cgctcaggac gaggacggcg ttcatcgccc ggtcgggttt
    26281 gccgcggtgc acgttccggt agtcaccggg gtcgcgcagc gacacgttga cctccagcgc
    26341 cgcgccctcg aggtccactc cggtgcggga ggacagccag gtgcggaagg agtcctgtac
    26401 gacctcgtcg agcagttcgg cccaggccgg gggcagcttc tcggccttcg gtgtgtgacg
    26461 cccgtcctga tgcaccgtca tgagccagag ccggtagtgc ttgtcgaact ccggcgcctc
    26521 tttcaccgcg cggatgaact cgctcatggc cggcggttcg gcgttgagcc ggcggaggtc
    26581 ctcggcgtcg atcaggtgga gtccggtgtg gtgcacatgt ggttccgcgt gggtgaccac
    26641 ctgggcgctg gctcgtatca aggtcgcctc gctggagtcg gggcccggtg cgcggtccgt
    26701 gggccgcggg gacggggcgc caccggcggt cgcccggtgg tgatccagag tctgcgccgg
    26761 gtgccttgcc gatctctcgc ccgaccgctg gccgactcct tgcgggggtc cttgcggccg
    26821 cccttgcagc tcgcgcccgg ggcgtcagcg cgggtggtgc ggggtgtcct ccagccgcgc
    26881 gcgtgcctgc ttcgcctccg ggtgtcccat gtcgtcgagg atccggacgg cctggcgcca
    26941 cacgaggacc gcggtgatgt gcgctccccg ggcctcgtgg gtgtctccca ggtgcaggag
    27001 ggtgtcggcc tggaggtagc ggtcgttcat gtgccggtac aggccgagcg cccgccggta
    27061 gcagtccagg gcctccggat ggtgccccag gtggtggtgg gcgagcccga ggctgtccca
    27121 cgcggccgcc tcgccgttga cgtcgccgat ggcccggtgc agcgagaccg cccggtcgca
    27181 ccaggtgatc gcgcgttcgt ggtcgccgag gaggatgtgg gtccagccgg tctcgttgag
    27241 gacgacggcc tggccgccga ggttgcggat gccccggtac agcgccaggg catgctcgta
    27301 gtggcgcagg gcctcggtgt gccggccccg ggcgttggcg aggaaggcca tctgacggcg
    27361 ggtccgggcc tgtcccgcgg cgtcgccggc ctcggtgaac agggtcaggg cacgccggag
    27421 gaacgcgtcg gcccggtcgt cctcgcagag gcgtccccag gcgaagccca gcgcccggca
    27481 ggcctgtgcc tcccgcaccg ggtccttcag cgagatggcc gcctccaggg ccgtccgctg
    27541 gacggctgtc tggtcctgcc atctgccctg ccggtcgagg tgcagttcca gtgcctgggc
    27601 cagcagccac gcgtgctgcg ggaagcccct gcgctgtgcg tacggcacgg cggacagcag
    27661 gaccggcagc tcgcggtcga gccacgccat ggcctcctgc cgtcccccga tcggttcggg
    27721 tgcgacgccc ggtgcggcct cgggttcgag cggggcctcg atgcggttcg gtatgagcgc
    27781 ctcggcggcc gcgtacgcgg tgtgcaggca gtggtcgagc agccgccgta cggcgagctg
    27841 ccgggtgtcc tcgtcctcca gttcgcggct ctgttcgagg gcgtggacct tcagcaggtc
    27901 gtggaaggcg aaccgctggg gacccgaacg ggccagcagg tgggcgccgt tcagggtggc
    27961 cagcagcgcc ctgacccggc gggccggcag ggcggcgaga ctggccgcgg cggcggcgga
    28021 gatgtccggg cccgggtgca gggcgagaag cctgagcagc cgtgccgcct gcgggcccac
    28081 actgcggcag gaccaggaga acacggtgcg caggtcggtg tagcggtcct cgcccgcgaa
    28141 gccgtcgagg ctgtcgcggt cgtcgaggag cgcggcggct acggaggcca ggggcaggtc
    28201 gggctgggtc gcggcatggg ccgcgacgat ggccagggcc agggggagcc gtccgcacag
    28261 gtcgatgatc tcgtcgacgg ccgcgggctc cgcggcggtg cgctcaccgc ccacgcggcc
    28321 ggcgaggact tcgcgtgact cctcgcggct gagcaggccc agggtgatcg gccgtgcccc
    28381 gtgggtggcg accaggccgc gcagctgggt gcggctggtg atgacgacca ggcacgagga
    28441 actgcccggc atcaggggcc gcacgtgctc ggagtcgagg gcgttgtcca gcaggatcag
    28501 gatccgcttg ccggccagga gactgcggta gagggcgacc cgtgagtcgg tgtcgggggg
    28561 caggtccctg gcgggcacgc cgagggcggt caggaacgag cgcagcacct ccgccgcggg
    28621 cacggcggac tcgctcacgt cgaacgcgcg taagttgacg tacagctgac cgtccgggaa
    28681 ccggtgggcg aggcggtgcg ccacgtgcac ggccagggtc gtcttgccga cgcccggcat
    28741 cccgtcgatg gcgctgatca ccaccgaggc ggccgccggc cggccgtcgt cgagagcgtc
    28801 cagcagctcg gtgaggcggg cgagttcggt gcggcgcccc acgaacgtgc acagatcggg
    28861 cggcagttgg gtcggccgca cagcgggggc gctctccggc gcgtgctgcc ggggcggcag
    28921 gtcggtgccg gagagcggtc ggccgtcgtc ggtaccgtcg gggggtgtct gcacatcgtg
    28981 cagcagacgg gcgcggacgg cgctgagttc cggcccgggc tcgacgccga cctggacggc
    29041 gagacgggcg cgcatcgtgt cgtacagggc gagcgcctcg gcctgccggc cggtggcggc
    29101 cagcgcctgg accagacgga cgtgcaggga ctcgtccaga gggtgcagcg cggcggcgct
    29161 ctggagcagt ggcagcatcc gctcgggtgc tccggtggcg agcacgaggt cggctccctc
    29221 gcgcagcacg gcgaggtgtt cgctgtcgac cgcgaagaac gccgggtggc cgcgtaactc
    29281 ctgcgggacg cccgccgcgg cctccccgcg ccacaacgac agtgcctggg tgaacagctc
    29341 ggcggcggcc tcggtgtcgc cgccggcccg ggcggcgcgg gcacgctgcg cgagttcgcg
    29401 gaaccgcagc agatcgaggg tgccggcgtc gacgtcgatg gcgtagccgc cgacgcggcg
    29461 caccagaagc cggccgggag cgcgcggcgc caggtggggt tccagcagct tgcgcagatt
    29521 gccgacatgc cggtggacga tgttcgccgc gctgctgggc gccccggcgg gccacagggc
    29581 gtccacgatc ctggacaggc tcacgggctg tccggcctcg agcaggagca gggccagcac
    29641 cgcccgctgc ttgggcggcc ccgggggcag ttccgcaccg tcccgccaga tcctgatggg
    29701 tcccaggacc ccgaaggcga tgtgtcgatc catgtcttcc cacaagcccg gccctgcggc
    29761 cgacgaaact gaaatgcgct gatcagagtg tatgtggcag gctctccggc aggccgtggc
    29821 cgccaagtgg agggagacgt tccttggctt gttctcaccg tcagtgcaac gtcactcttt
    29881 ccgcacaggg gcatgtgtag cctgctcgcc gcacgtactg agcgagtgga aggcatatgc
    29941 accaggcatg atgtatgcaa cggaagtaca ccagccccgg actctgacgg cggacctctc
    30001 actcgaagca tttggcgtga tgacggcacg gcggggcagc gagccggtgc acctcggacc
    30061 tccgaggcac cgggcggtcc tcgggctgct gatgctgcgc ctcggacagg tggtccgcgt
    30121 cgaccagctc gtcgacgagt tatggggcga caaaccgccg cgccggcccc acgccaccct
    30181 ccagacctac atgtctcatc ttcgacgggc cctgacgtcg ggtcacggca aggacgccgg
    30241 ggtggctccc ctgcactacc gggcgcccgg atacgtcctc gcgctggatc cgcaggccat
    30301 cgacgtgtgc cggttcgacg agatggtctc ccgcggacaa cagcacgccg ccgagggccg
    30361 gttcggtgag gcgcgcgagg cgctcgactc cgcgctgcac ctgtggcggg ccgacccctt
    30421 cctggatctc acgtcctacg agccgctggc cgaggagagc gcacgcctcc agcacctgcg
    30481 cacggcggcc gtgacgatcc gcgccgaggc cctgctcgcc ctcggcgacg cgcggaccac
    30541 ggtggagtcc ctgcggcgcg aggtgatccg cttcccctcg gacgaacgca tcgtggccgc
    30601 cctgatgacc ggcctgtacc ggctcggcca gcagaccgag gcgctccgcc tgtacgaacg
    30661 tacgcgcacg cagctgtcgg aggagctggg cgtggcaccg ggcgacgacc tgcggcgcgt
    30721 ccatctggcc atcctgcggc acgaactggg cggcgccgca ccggccgggc agcgggccga
    30781 ggtgcgggcc cggccggacc gcgagccccg gagcgaggag agccgtccgc cggccgacgc
    30841 cgtccacggc cgcgccgccg accccgcgac gaccggcacc ggacccggcg ggcacaccgg
    30901 cgcgcggcct gtggacgacg ccgccgggtc cggcaggacc ccggcccacg cgtcgccgct
    30961 tccgctcttc gaagggcgcg aacacgccct ggcctcgctg cgccgctcca tcacggccgc
    31021 cctggagggc agcggacatc tcaccgcggt cgtgggtcag gccggggtgg gcaagaccga
    31081 actgctggcc caggccacgg cgcacgccgc cggatgggtc gccggaaccc gggtggtccg
    31141 ggtgagctgc cggaccgcgg agggcatgcc ggcctgctgg gtgtggcagc aggcgctgcg
    31201 gatgctcggc ggccccgacg cgctgccggg cgacaatgcg ccccggctct gtccggaccc
    31261 tacggtgaca acgctgtcag actcaccgga gggagcggac gccgaccgcc gggagcagac
    31321 ccagcagcgc ttcctggccc acgacgccct gagtgaaacg attctgcgcc acgcggacga
    31381 cgctcccctc ctgctcgtcc tcgagaacgt gcacctggcg gaccgcccca cgctcgacgt
    31441 cctcgcactg ctcagcgacg gcacacaggg ccgcgcggtg agcgtggtga tcagcgtccg
    31501 ggagtccggt gtgggagccg gagccgaacc cgacggcccg ctccaggagt tgctggccga
    31561 ctcccgcacg gacgtcgtcc acctcgacga cctgtccgag gaacaggtcc agaccctcct
    31621 cgcggcccag ggcgggcccg gcccggccac gcccgtggtg cgcggactct acgaacgcag
    31681 cggcgggaac ccctacctgc tcggccagct actggcacac gcgggtggtg cccgctccct
    31741 gcacgccgcg cgcgcggcac gccaggtcct caccgagatc cccaccggcg tgtccagcat
    31801 gctgcgccgc cgtctggccg gactggcccc ggaggtcctg cgcgtgctca ggggatgcgc
    31861 ggtactcggg accgaggccg acctgaccct gctgaccacc gtgctcggcg acaccacccc
    31921 cggcgtccgc gccgtggagg aggcgctgcg caccggtctg ctgcgccgcg accacgatca
    31981 cgcccgcacc ctggtgttcc gctacggcct ggtacgcgac gtactgctcg ccgagatgag
    32041 cgacc
//
