LOCUS       NZ_BMRD01000012        34518 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Actinomadura citrea strain JCM 3295 sequence12, whole genome shotgun
            sequence.
ACCESSION   NZ_BMRD01000012
VERSION     NZ_BMRD01000012.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Actinomadura citrea
  ORGANISM  Actinomadura citrea
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 274361)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: BGI assembly pipeline
            Genome Coverage                   :: 127X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014648455.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 03:26:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,339
            CDSs (total)                      :: 8,265
            Genes (coding)                    :: 8,175
            CDSs (with protein)               :: 8,175
            Genes (RNA)                       :: 74
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 90
            CDSs (without protein)            :: 90
            Pseudo Genes (ambiguous residues) :: 0 of 90
            Pseudo Genes (frameshifted)       :: 12 of 90
            Pseudo Genes (incomplete)         :: 83 of 90
            Pseudo Genes (internal stop)      :: 3 of 90
            Pseudo Genes (multiple problems)  :: 8 of 90
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:33:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 239843
            Orig. end                         :: 274361
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMRD01000012.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..34518
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="3"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..34518
                     /SMILES="NC([*])C(=O)NC(CO)C(=O)NC(C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..34518
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[20000:30550](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..30550)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     misc_feature    1279..1294
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.56"
                     /tool="antismash"
     gene            complement(1500..3224)
                     /locus_tag="IEZ14_RS26865"
                     /old_locus_tag="GCM10010177_54200"
     CDS             complement(1500..3224)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012851497.1"
                     /locus_tag="IEZ14_RS26865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_54200"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_179832859.1"
                     /transl_table=11
                     /translation="MSAELLPVATPAQVRAYARRLVLRHPRDLAGVLALHALAALTGLV
                     TPRLLGSLVEGVRDGGADIDTTGLAIAGFVIVQSVLIRYAYLASAKLGERVLAELREEF
                     VDRVMALPLSTVERAGTGDLVTRASRDVDTLSTSVRYAMPETLVAVVVGGFTVAALMLN
                     GPLVALPALVAVPLLVAVMRWYLPRAHNGYLRENASWARIADGLTETVQGARTVEALGL
                     AERRHERGDADIAASYKVERYTLRLRTVLFPVMEMSFVLPVVSTLLVGGLLYINGMATL
                     AQVTAATLYAQQLIEPVDTLMQWLDELQLGGASLARLLGVGNVPPDRAPNGARPTGERI
                     AARDVHYSYRRGHDVLHGVDLDLRPGERLAMVGPSGAGKSTLGRLLAGVDGPRAGAVTV
                     GAGGGVPLVELTLDDLRGHVALVTQEHHVFRGTLRENLVMAREGASDDDIRQVLAAVDW
                     DGPGLDAVVGSGGETLSPAQAQQLALARLVLADPHTLVLDEATSLLDPRAARRLERSLA
                     AVLDGRTVVAIAHRLHTAHDADRVAVVEDGRITELGTHEELLAAQGSYAALWASWRS"
     gene            complement(3221..4975)
                     /locus_tag="IEZ14_RS26870"
                     /old_locus_tag="GCM10010177_54210"
     CDS             complement(3221..4975)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012894826.1"
                     /locus_tag="IEZ14_RS26870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_54210"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_229810440.1"
                     /transl_table=11
                     /translation="MKPLPVKDPGGPDHVARGRTTSLDPWSASRADRGSPARYLLSLLR
                     VQWRSVTAGALLGVAWMLSQALMPAALGRAIGDGVAARDEGALVTWAAVLLGLGVAQAV
                     TGVLRHRCAVFNWLSAAYRTVQLVTRQSTRLGSTLPKRLSAGEVVSVGLSDVSHIGDTI
                     DIVARGSGAVVAIVVVAGILLSTSPPLGLIVLVGVPLILVAAAPLLRPYREREQAHREL
                     VGELTTHATDLVAGLRVLRGIGGEALYSGRYRAESQRVRGAGVAVARAETRMNGAEVLL
                     PGLLIALVTWAGARFAARGEIGVGELVAFYGYAVFLIVPLKTLGEAASKITKGLVAAGR
                     VTALLRLDPELPATGTARPAAHAELVDIASGLVVRPGRVTAIAAADPRDAQAVADRLGR
                     YESGEVDFGGVPLRAVEDVRKRILVAVNEDRLFSGPLAESLAPGAGEAVLRAAVRAACA
                     EDVVDSAGLDAHVAEAGREFSGGQQQRLRLARALAADPDVLVLVEPTSAVDAHTEARIA
                     GRLGEARAGRTTVVCTTSPLMLDRADHVAFVRDGLVVAEGTHRELLDAEPRYAATVTRG
                     ETAERAGT"
     misc_feature    complement(5010..5026)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.7"
                     /tool="antismash"
     misc_feature    5030..5041
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.26"
                     /tool="antismash"
     gene            5279..6511
                     /locus_tag="IEZ14_RS26875"
                     /old_locus_tag="GCM10010177_54220"
     CDS             5279..6511
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018655743.1"
                     /locus_tag="IEZ14_RS26875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_54220"
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /protein_id="WP_229810441.1"
                     /transl_table=11
                     /translation="MSTISHQTHPLTPGTEDRIELLLIDDDPTDVLMVEKMLADSGLDA
                     GITVASDLDAARRMLTRRTQCIIVDLSTPDIDRLEGLRRVLALSGPAAVVVLTGLDDGR
                     LGVQAVAAGAEDYLVKQEVDGPLLARAIRYAIERKRSEETERRLVEARILGRENARLER
                     GLLPVPLIEDPTLRHHTRYRPGRRRALLGGDFYDTVQTEGGAVHLVIGDVCGHGPDEAA
                     LGVQLRMAWRTLVLAGHTGEQLLGTLDTVLGHERRSEEIFTTLCMVTIAPSRRTARMHL
                     AGHPAPLLFRGAPGAGGEVAALPDYAHGPALGLVPGAEWPTTEIDLGESWGLMLYTDGL
                     IEGRIGEGSDRLGTDGLVGLARTARARGAAGRSLIDALVAEVERLNGDALTDDLAVLLL
                     SRQAETDRPGR"
     misc_feature    6576..6591
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     gene            6713..7402
                     /locus_tag="IEZ14_RS26880"
                     /old_locus_tag="GCM10010177_54230"
     CDS             6713..7402
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017541863.1"
                     /locus_tag="IEZ14_RS26880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_54230"
                     /product="succinate dehydrogenase cytochrome b subunit"
                     /protein_id="WP_179832857.1"
                     /transl_table=11
                     /translation="MAIAIPAIYRSTVGKKAVMAVTGGILVLYLVAHMIGNLKIFLGAE
                     EFNHYAHWLRTMGEPAVPRRTVLTIIELVLGASVVLHMWSAVSLGKRAAHARPVKYQSK
                     KKSHAQGYAVRTMRYGGVIIAVYIIWHLLDLTFFVVNPKGADATPYQRMVADFDPSRWY
                     ITVWYVVAVLLVGLHLNHGIWSAFQTLGLRSPRSHNALRGLAATTAALVTLGFVAVPVS
                     ITFGWVS"
     gene            7407..9344
                     /locus_tag="IEZ14_RS26885"
                     /old_locus_tag="GCM10010177_54240"
     CDS             7407..9344
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018655745.1"
                     /locus_tag="IEZ14_RS26885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_54240"
                     /product="fumarate reductase/succinate dehydrogenase
                     flavoprotein subunit"
                     /protein_id="WP_179832856.1"
                     /transl_table=11
                     /translation="MTDGFYKSGEPIADAKAPAGAIEERWTTRKFEAKQVNPANKRKKK
                     IIIIGTGLAGGSAGATLGEAGYHVQQFCFQDSPRRAHSIAAQGGINAAKNYRNDGDSVY
                     RLFYETVKGGDFRSRESNVYRLADISRQIIDQCVAQGVPFAREYGGLLDNRSFGGTQVS
                     RTFYARGQTGQQLLLGAYQALMRQVDAGNVELYPRHEMLDLIMEDGRARGVVVRNLING
                     EVKHYTADAVVLASGGYGNVYFLSTNAMGSNVTASWRAHRHGALFANPCYTQIHPTCIP
                     VSGDHQSKLTLMSESLRNDGRVWVPKKAGDTRRPYDIPEDERDYYLERIYPSFGNLVPR
                     DIASRAAKNVCDEGRGVGPGGLGVYLDFADAIARLGRDKVEAKYGNLFEMYERITGENP
                     YDTPMRIYPAVHYTMGGLWVDYDLESTIPGLFVIGEANFSDHGANRLGASALMQGLADG
                     YFVLPNTIGDYIARNSLPPVAETAVSEAEERVRTRIERLLSIDGDRTVDSFHRELGHIM
                     WEYCGMERTEEGLRKALDLIPALREEFWTRVKVTGRGEELNQQLEKAGRVADFFELAEL
                     MVVDALHRAESCGGHFRAESQDEDGEAKRDDDNFAYVAAWEWAGEDAQPVLHKEALNFD
                     YVKPTQRSYK"
     gene            9344..10096
                     /locus_tag="IEZ14_RS26890"
                     /old_locus_tag="GCM10010177_54250"
     CDS             9344..10096
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630080.1"
                     /locus_tag="IEZ14_RS26890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_54250"
                     /product="succinate dehydrogenase/fumarate reductase
                     iron-sulfur subunit"
                     /protein_id="WP_179832855.1"
                     /transl_table=11
                     /translation="MKLTLRVWRQSGPQDKGGMVEYKLDDVSPDASFLEMLDVLNEKLI
                     ASGEEPVAFDHDCREGICGMCSLVINGTPHGPERATTTCQLHMRKFKDGEVIDIEPWRA
                     RAFPVVKDLVVDRSAFDRMIQAGGYISAPTGTAPEAHATPVPKPDADRAFEAAECIGCG
                     ACVAACPNGSAALFLGAKVTHLGLMPQGQPERWDRVVSMLDTHDQEGFGGCTNTGECTV
                     ACPKGIPLDVIGRLNHDYLKATAGGKKR"
     gene            10000..10905
                     /locus_tag="IEZ14_RS26895"
                     /old_locus_tag="GCM10010177_54260"
     CDS             10000..10905
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012703.5"
                     /locus_tag="IEZ14_RS26895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_54260"
                     /product="arginase family protein"
                     /protein_id="WP_338070768.1"
                     /transl_table=11
                     /translation="MHRRLPEGHPAGRHRPAEPRLPEGHRRREEAVTAAPRSRSRPEHR
                     AGPFYCVRMNVTLLPYHQDERLPDASFPLSGLDVVPVTPDLPDGDVWQRVAALFEPVVA
                     EVARQIDGGSMPRVVSGDCLTAEAVLAGVQKAGVDASVVWFDAHGDVHTVDSSTSGYLG
                     GMPLRQILGADTALLPDRLGLRTLPEDRAVLVDARDLDPAEAEFLASSQVRRCPVDDVV
                     LPPGPLLLHIDVDVIDAGEMPGLKFPVGGGPSYDAVVASVRRIMATGRVAALDVACPWH
                     PPEGDDDAVRTRLLKDLLTA"
     gene            11004..12791
                     /locus_tag="IEZ14_RS26900"
                     /old_locus_tag="GCM10010177_54270"
     CDS             11004..12791
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024816.5"
                     /locus_tag="IEZ14_RS26900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_54270"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_189269949.1"
                     /transl_table=11
                     /translation="MHCAGGAGPAVHRTILRLDVEGYGRRTNGDQLAVRAGLYRALRRA
                     LDESGVPAASCYCEDRGDGAMILIRPDVPKELLAGAFPARLAALLARHNGGAPPDARIR
                     VRVAVHAGEIHHDDHGVAGTAINKAFRLLAADPLKDALRDSPGVLALITSGWFFEEVVR
                     QNPACRAAAFRPAQVAVKELREQAWMRLPDSWPHADSARTLRLLALHPGAEISVPAAAV
                     LIGVPDAEARLLLGDLGLVERGEGRYGVPAPDPGRDPGPALAPQERSAAVRRVLAWYLG
                     TADNARRLLCPDRITAPPLPDEPGRALRFASADEARRWCETERPNLVAAARAAADEGHH
                     DIAWRLPLALWTFFFLRGPWTDRSEALRNGLASARLLGDDRGIAYVLGGLGYASQSRWR
                     FEESVELFTAACEVFSRLGDVRGEAWTLHGLGYACRRLQRYREAVAHHRRSVLLAAAVG
                     DRRNTGRALTALGYAYAGLADFGSSLDHFEQAHGIALEADGRTLGWTLHGLGYAHHGLR
                     RLHTAIVHYEKALNVFREFGDRPGQGETLYNLGRAHMQMSRPDAARDCWLLALAIFEDL
                     RTPQTEGVLARLRSLDPRS"
     misc_feature    11115..11117
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12796..13389
                     /locus_tag="IEZ14_RS26905"
                     /old_locus_tag="GCM10010177_54280"
     CDS             12796..13389
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEZ14_RS26905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010177_54280"
                     /product="hypothetical protein"
                     /protein_id="WP_179831319.1"
                     /transl_table=11
                     /translation="MTLQQHMRRAAEDALRSFPEALLPDIYVISLRISHGEFSTVHELW
                     DYPYDPYMAIGYNTESNVRQNLEGSSADPLEVRWNYACMLLEESGPAGHHPADPEGTAL
                     YLDEVKRLGLWYEPDEDAEAEQDEQDERLCAHFDDLCIDAARHLHSTGLVQKVLGREVP
                     IILFDMFRVIEPGATQAANPPRLVPAGYLTFQQG"
     gene            complement(13503..14123)
                     /locus_tag="IEZ14_RS26910"
     CDS             complement(13503..14123)
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012422.5"
                     /locus_tag="IEZ14_RS26910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_179832852.1"
                     /transl_table=11
                     /translation="MIRLGIIDPRPVILHGLRYVFNKAQEVTIEVSQSNTNGVPSNTLD
                     VVLLGFCPSDGVARGRQITELSHKTSVLILSWARGPEEREEAVRCLRAGARGVLHPDAP
                     VNTLLDAVRTAAAGRMVIPNEVSSFLETPAATDQLSLREQQVLDCIANGYTHGQIARHL
                     GISRHTVDTYVKRIRGKLNLGNKAELTRAAVQAVSGFGIRHAQ"
     misc_feature    complement(13851..13853)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(14571..15953)
                     /locus_tag="IEZ14_RS26915"
                     /old_locus_tag="GCM10010177_54300"
     CDS             complement(14571..15953)
                     /EC_number="2.3.1.-"
                     /NRPS_PKS="Domain: PKS_AT (91-405). E-value: 2.3e-82.
                     Score: 268.6. Matches aSDomain:
                     nrpspksdomains_IEZ14_RS26915_PKS_AT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012901.5"
                     /locus_tag="IEZ14_RS26915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_54300"
                     /product="acyltransferase domain-containing protein"
                     /protein_id="WP_179832851.1"
                     /sec_met_domain="PKS_AT (E-value: 9.7e-82, bitscore: 268.6,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRPYELVVLSASSSDELAAAARGLARFLAGRPSLPLAAVAGSLV
                     HDRPRLPHRLALVARDCADAARRLQAPAARETHIGHATTAERPLAFLFPGVGDHYAGMA
                     AGLYRSEPLFRSALDHCAEVLINQLGRDLREILYPENGEAAPPADGPHGRLDLARLLGR
                     DERSGELDRTATAQPLVFAVEYALARFLMGAGIRPTALAGYSLGEYVAACAAEVLAPED
                     ALELVARRAKLIETAPEGAMVAVMLGADHLADHLDGELSLSAADGPRLSVVGGRITAVE
                     RLERRLAAEGVASLRLPTRHAFHTAMLEPFEEGMRELAAGFPLRPPTIPLLSNVTGTWL
                     TEVQATSPEYWAQHMSRTVRFEDELAELWRLPAPILVEVGAGRTLGTLVQQHPGRRPDG
                     TILSTLPTTAARDSDVAGVLTALGRLWVEGVDVNWPALFPDGPRERLPHFVFEGDQTET
                     KR"
     CDS_motif       complement(14640..14702)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26915_0006"
                     /evalue="7.80E+00"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="IEZ14_RS26915"
                     /protein_end="438"
                     /protein_start="417"
                     /score="0.6"
                     /tool="antismash"
                     /translation="VLTALGRLWVEGVDVNWPALF"
     aSDomain        complement(14739..15680)
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: False"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS26915_PKS_AT.1"
                     /evalue="2.30E-82"
                     /label="IEZ14_RS26915_PKS_AT.1"
                     /locus_tag="IEZ14_RS26915"
                     /protein_end="405"
                     /protein_start="91"
                     /score="268.6"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFPGVGDHYAGMAAGLYRSEPLFRSALDHCAEVLINQLGRDLREI
                     LYPENGEAAPPADGPHGRLDLARLLGRDERSGELDRTATAQPLVFAVEYALARFLMGAG
                     IRPTALAGYSLGEYVAACAAEVLAPEDALELVARRAKLIETAPEGAMVAVMLGADHLAD
                     HLDGELSLSAADGPRLSVVGGRITAVERLERRLAAEGVASLRLPTRHAFHTAMLEPFEE
                     GMRELAAGFPLRPPTIPLLSNVTGTWLTEVQATSPEYWAQHMSRTVRFEDELAELWRLP
                     APILVEVGAGRTLGTLVQQHPGRRPDGTILSTL"
     CDS_motif       complement(14871..14906)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26915_0005"
                     /evalue="5.90E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="IEZ14_RS26915"
                     /protein_end="361"
                     /protein_start="349"
                     /score="13.3"
                     /tool="antismash"
                     /translation="YWAQHMSRTVRF"
     CDS_motif       complement(14943..14975)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26915_0004"
                     /evalue="1.60E-03"
                     /label="PKSI-AT-M_m7"
                     /locus_tag="IEZ14_RS26915"
                     /protein_end="337"
                     /protein_start="326"
                     /score="11.1"
                     /tool="antismash"
                     /translation="PTIPLLSNVTG"
     CDS_motif       complement(15252..15371)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26915_0003"
                     /evalue="2.50E-20"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="IEZ14_RS26915"
                     /protein_end="234"
                     /protein_start="194"
                     /score="64.7"
                     /tool="antismash"
                     /translation="GIRPTALAGYSLGEYVAACAAEVLAPEDALELVARRAKLI"
     CDS_motif       complement(15390..15425)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26915_0002"
                     /evalue="2.00E-03"
                     /label="PKSI-AT-M_m2"
                     /locus_tag="IEZ14_RS26915"
                     /protein_end="188"
                     /protein_start="176"
                     /score="11.1"
                     /tool="antismash"
                     /translation="QPLVFAVEYALA"
     CDS_motif       complement(15630..15683)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26915_0001"
                     /evalue="8.80E-04"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="IEZ14_RS26915"
                     /protein_end="108"
                     /protein_start="90"
                     /score="12.1"
                     /tool="antismash"
                     /translation="FLFPGVGDHYAGMAAGLY"
     misc_feature    16019..16032
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.32"
                     /tool="antismash"
     gene            complement(16029..16253)
                     /locus_tag="IEZ14_RS26920"
                     /old_locus_tag="GCM10010177_54310"
     CDS             complement(16029..16253)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1009: mbtH-like protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016711157.1"
                     /locus_tag="IEZ14_RS26920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_54310"
                     /product="MbtH family protein"
                     /protein_id="WP_179832850.1"
                     /transl_table=11
                     /translation="MFDDDDERTYRVVTNHEEQYSIWPEDREIPAGWRAEGTRGTKPEC
                     LAHIDQVWTDMRPLSLRRQMDSQAVPGSS"
     gene            complement(16293..18143)
                     /locus_tag="IEZ14_RS26925"
                     /old_locus_tag="GCM10010177_54320"
     CDS             complement(16293..18143)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.5"
                     /locus_tag="IEZ14_RS26925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_54320"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_179832849.1"
                     /transl_table=11
                     /translation="MRAPRTRRSEPPPAPPRGRSVRRALLIPLLSRSAPTYLGLTGLWI
                     LLRGALLATGLLLQMVFDTLSGTDPAGTSAWSLIALVAAAEATKVTVWYGVILSRVEPH
                     FTYRIRAALQVNALRAILRKPAGRALDRTGGDAVSRFGADTDEVGVFAIWSASNLSRLI
                     IAVAALIIMLGIDAVVTLGLVVPVVVMVLASRALARPLRECQNAGRRAAAEVSSVVGEA
                     VGGVQAIKVGRAEERFVARLRQANAVRLRLAAREVLLTTVQTSLFNGTAALGTGFVLLL
                     AAARMRGGEFTVGDLALFVFYIQFITEAVTALGMFFARFQKAELSTRRVAELADDESAV
                     IARTRTHLRREPPRPAPREDRSAPLRLLEARGLTSRYPGTSRGVRDIDLHLPAGTVTVV
                     TGRVGSGKSTLLQVLLGLLPAERGTVLWNGVPVDHPETFLTPPRSSFVPQVPRLFSGTI
                     RENITLGAPSSPTEVAEAVRLAVLEDDIAGLDKGLDTVIGPRGLRLSGGQRQRIAAARM
                     AVRRTDLMVFDDLSNALDVTTERRLWDRLLDHGGATILAVSHRPSILRRADQIVVLVDG
                     EMSAVGTLDELLETCTEMHHLWDADESLPGDAHAGRVEHD"
     gene            complement(18140..19918)
                     /locus_tag="IEZ14_RS26930"
                     /old_locus_tag="GCM10010177_54330"
     CDS             complement(18140..19918)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.5"
                     /locus_tag="IEZ14_RS26930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_54330"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_179832848.1"
                     /transl_table=11
                     /translation="MAHASAEPSSTGNADGTVGSNAARTLRTYLGPHRAVAAVLAVTTL
                     VYTALQVANPQLLGRFIDGVRSGAPLSNLLGLGAIYLSVAVVAQVIWIVAEYRGARVAW
                     SATNELRADLTEHCLRLDMSFYERHAPGELIDRIDGDVSKLANYFSQMFLLVLSNVLLV
                     VGIGVALFVQDWRIGLVYAPFVTASFFLLRRLVGTAVPAMAAQREANAKLLGFFEERLN
                     GLPDLRANGAEEHTVHGFWTYAGTLFWASRRAALLGVRWPAAAQSLASAGFVMALGAGV
                     WLYTSGQITLGAAYTLVVYAVMVQTPMLVITSQFHDLEAALGALRRIHGLLDEHSVVRT
                     GEATLPAGAPAVEFERVSFSYRPEEDALRDISLRLRPKTRLAIVGRTGSGKSTLIRLLF
                     RFADPTQGTVRFDGRDVREISVASLRDQVGLVTQEVQLFAATVRDNVTLFDDTVDDARV
                     REALAEVGLRQWLESLPAGLDTLLGPGDTGLSAGQEQLLAFARVLIQDPGLVLLDEATS
                     RLDPASLRVFETAMERLLAGRTAIIVAHRLETLGTVDEVLLLSDGRVAEHGPRDRLVAD
                     PSSRFSRLLAANEALA"
     misc_feature    complement(19977..19990)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.11"
                     /tool="antismash"
     gene            complement(20001..24683)
                     /locus_tag="IEZ14_RS26935"
                     /old_locus_tag="GCM10010177_54340"
     CDS             complement(20001..24683)
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (2-29). E-value: 1.9e-08.
                     Score: 25.4. Matches aSDomain:
                     nrpspksdomains_IEZ14_RS26935_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (8-308). E-value:
                     5.1e-107. Score: 349.4. Matches aSDomain:
                     nrpspksdomains_IEZ14_RS26935_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (475-873). E-value:
                     1.9e-119. Score: 390.9. Matches aSDomain:
                     nrpspksdomains_IEZ14_RS26935_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (985-1050). E-value: 3.5e-23. Score:
                     73.6. Matches aSDomain: nrpspksdomains_IEZ14_RS26935_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (1072-1382). E-value:
                     1.4e-97. Score: 319.2. Matches aSDomain:
                     nrpspksdomains_IEZ14_RS26935_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1388-1552). E-value: 1.2e-44.
                     Score: 143.9. Matches aSDomain:
                     nrpspksdomains_IEZ14_RS26935_TIGR01720.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.5"
                     /locus_tag="IEZ14_RS26935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_54340"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_179832847.1"
                     /sec_met_domain="Condensation (E-value: 5.4e-64, bitscore:
                     210.1, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.5e-132, bitscore:
                     435.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6.6e-14, bitscore:
                     46.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMIDNGEVEKVFPLTAMQQGMLLHSVGDPAAGFYVNQIVFTLRGP
                     LDASRLRDSWQWVADRHPALRTAFVWEGTDEPLQVVRTSVPVPWTELDWRAVSHEEREQ
                     ELSGLLEDDRSRPFELARAPLVRMVLVRLTDEDWWLVLTFHHLLLDGWSVQLVVDDAFT
                     RYRRADADGTEEAAPGPPHWEYVAWLHGQDPAAAERHWREHLAGFREPTPLSVGHPAAR
                     GEPGFGEITDVLPDELRARLEDLAKRRHLTLGTVVHGAWALLLSRYSGQRDVVFGSVVS
                     TRPPQVPDVERMVGLLSATLPIRVRVDESAPLLQWLATLQKDLAAGRRYDYSPLAQVQR
                     WSDVPGGTALFDSIVAYENYPVRTGWLGADEDLRVTGVRAHERPHYPVTLVVAGTDDLE
                     VRLHHDRRRLSDPAAERLLGHLRTLLTGIADGLADDQDRPVGGLRHLTSAEGDRLLRDW
                     ADGGEPDLLGPTVPELLDEQARRRPDALAVICGEQRLTYRQFDVRINRLAHHLRAAGVG
                     PDVPVAVCLERSVELLVALLAVVKAGGCYVPLDPEYPEARIASLIADTGVRLVLTGGTA
                     ADRLPRAGAARVMRLEAEAEEIGRAPATPPEPGVSSDNLLYIICTSGSTGRPKGVMTTH
                     RGVLNHLGWMQRTFPIGPGDRIAQRTSVGFDASVWEVFWPFLTGAALVVPDTDAKDPER
                     LAQVMDEHKVTVVSYVPSLLNTVLADPRRRLGHHLRLVLIAGEALPAGLVNAFREVCHA
                     EAANVYGPTETSVSCVIWPVPDRSDVTRVPIGRPLTGTRGYVLDPELRPVPAGVPGELY
                     VGGSGVARGYLARPGMTAERFVPDPFGTGGGRLYRTGDLVRWMPDGCLEFVGRADHQVK
                     VRGFRIELGEIEAVLSGHPAVRDVVVTTQDQEDTSSRRLVAYVLPARGAEPVPVSELRD
                     HLAARLPDYMVPAVFVWLDALPLTANGKVDRAMLPAPDGVRPELAQEFVPPRDPAEKTL
                     GAIWADVLGVDRVGALDNFFELGGDSILSIMVVSRAAQEGLRITPRQFFDKQTVRELAA
                     VAEPMTRPIGVRHARKGSAADARDLPLTPVQHWFFEQGLTRPGHWNQGWLFALDADADC
                     ARIAGHLRDVVAALGDRHEALRLRFDRSGPHGRWHAEARAVDRAATDESVTLVDVAESD
                     DWDAALGAALAAAAEFDLGRPPLLRVLVIDGGRPDRRRLALLAHHLVIDGVSWRVLLED
                     LHTAFRQAATGAPVRLPSATTPISAWARALRELAHAPETEADLDFWLSQTSADPAGPEP
                     DLPQPPEHAREEDTARTTVGLDVEQTRLLLREVPRAYRTHIDDVLLTALTRALTRSTAS
                     NHVSLWLEGHGREQHLVDGADLSRTLGWFTSIAPVTLSLPPGDDPGTALKAVKEQLRAV
                     PHHGLSYGLLRYLHSAHASTLAARPAPRVGFNYLGQFDTAIAGDHTEPGAHDGPALRLR
                     RAPESPPPAFHPENARPHLLDIDAITIDGHLDITFSYSTAHYSDQAVERLAEETIAGLR
                     ELISHCTRPEAGGYTPSDFPESGLDQDRLDTLLTALTEDR"
     aSDomain        complement(20028..20519)
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS26935_TIGR01720.1"
                     /evalue="1.20E-44"
                     /label="IEZ14_RS26935_TIGR01720.1"
                     /locus_tag="IEZ14_RS26935"
                     /protein_end="1552"
                     /protein_start="1388"
                     /score="143.9"
                     /tool="antismash"
                     /translation="GTALKAVKEQLRAVPHHGLSYGLLRYLHSAHASTLAARPAPRVGF
                     NYLGQFDTAIAGDHTEPGAHDGPALRLRRAPESPPPAFHPENARPHLLDIDAITIDGHL
                     DITFSYSTAHYSDQAVERLAEETIAGLRELISHCTRPEAGGYTPSDFPESGLDQDRLDT
                     L"
     aSModule        complement(20028..24659)
                     /complete
                     /domains="nrpspksdomains_IEZ14_RS26935_Condensation_DCL.1"
                     /domains="nrpspksdomains_IEZ14_RS26935_AMP-binding.1"
                     /domains="nrpspksdomains_IEZ14_RS26935_PCP.1"
                     /domains="nrpspksdomains_IEZ14_RS26935_Epimerization.1"
                     /domains="nrpspksdomains_IEZ14_RS26935_TIGR01720.1"
                     /locus_tags="IEZ14_RS26935"
                     /monomer_pairings="Ala -> D-Ala"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(20439..20501)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26935_0014"
                     /evalue="7.60E-12"
                     /label="NRPS-E6"
                     /locus_tag="IEZ14_RS26935"
                     /protein_end="1415"
                     /protein_start="1394"
                     /score="37.2"
                     /tool="antismash"
                     /translation="VKEQLRAVPHHGLSYGLLRYL"
     aSDomain        complement(20538..21467)
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS26935_Epimerization.1"
                     /evalue="1.40E-97"
                     /label="IEZ14_RS26935_Epimerization.1"
                     /locus_tag="IEZ14_RS26935"
                     /protein_end="1382"
                     /protein_start="1072"
                     /score="319.2"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVIDG"
                     /tool="antismash"
                     /translation="LPLTPVQHWFFEQGLTRPGHWNQGWLFALDADADCARIAGHLRDV
                     VAALGDRHEALRLRFDRSGPHGRWHAEARAVDRAATDESVTLVDVAESDDWDAALGAAL
                     AAAAEFDLGRPPLLRVLVIDGGRPDRRRLALLAHHLVIDGVSWRVLLEDLHTAFRQAAT
                     GAPVRLPSATTPISAWARALRELAHAPETEADLDFWLSQTSADPAGPEPDLPQPPEHAR
                     EEDTARTTVGLDVEQTRLLLREVPRAYRTHIDDVLLTALTRALTRSTASNHVSLWLEGH
                     GREQHLVDGADLSRTLGWFTSIAPVTLSL"
     CDS_motif       complement(20544..20594)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26935_0013"
                     /evalue="1.60E-07"
                     /label="NRPS-E5"
                     /locus_tag="IEZ14_RS26935"
                     /protein_end="1380"
                     /protein_start="1363"
                     /score="23.5"
                     /tool="antismash"
                     /translation="DLSRTLGWFTSIAPVTL"
     CDS_motif       complement(21006..21071)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26935_0012"
                     /evalue="3.80E-11"
                     /label="NRPS-E2"
                     /locus_tag="IEZ14_RS26935"
                     /protein_end="1226"
                     /protein_start="1204"
                     /score="35.1"
                     /tool="antismash"
                     /translation="LALLAHHLVIDGVSWRVLLEDL"
     CDS_motif       complement(21432..21461)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26935_0011"
                     /evalue="3.20E-04"
                     /label="NRPS-E1"
                     /locus_tag="IEZ14_RS26935"
                     /protein_end="1084"
                     /protein_start="1074"
                     /score="13.6"
                     /tool="antismash"
                     /translation="LTPVQHWFFE"
     aSDomain        complement(21534..21728)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS26935_PCP.1"
                     /evalue="3.50E-23"
                     /label="IEZ14_RS26935_PCP.1"
                     /locus_tag="IEZ14_RS26935"
                     /protein_end="1050"
                     /protein_start="985"
                     /score="73.6"
                     /tool="antismash"
                     /translation="EKTLGAIWADVLGVDRVGALDNFFELGGDSILSIMVVSRAAQEGL
                     RITPRQFFDKQTVRELAAVA"
     CDS_motif       complement(22035..22100)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26935_0010"
                     /evalue="1.60E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="IEZ14_RS26935"
                     /protein_end="883"
                     /protein_start="861"
                     /score="39.2"
                     /tool="antismash"
                     /translation="FVGRADHQVKVRGFRIELGEIE"
     aSDomain        complement(22065..23258)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS26935_AMP-binding.1"
                     /evalue="1.90E-119"
                     /label="IEZ14_RS26935_AMP-binding.1"
                     /locus_tag="IEZ14_RS26935"
                     /protein_end="873"
                     /protein_start="475"
                     /score="390.9"
                     /specificity="substrate consensus: Ala"
                     /tool="antismash"
                     /translation="DEQARRRPDALAVICGEQRLTYRQFDVRINRLAHHLRAAGVGPDV
                     PVAVCLERSVELLVALLAVVKAGGCYVPLDPEYPEARIASLIADTGVRLVLTGGTAADR
                     LPRAGAARVMRLEAEAEEIGRAPATPPEPGVSSDNLLYIICTSGSTGRPKGVMTTHRGV
                     LNHLGWMQRTFPIGPGDRIAQRTSVGFDASVWEVFWPFLTGAALVVPDTDAKDPERLAQ
                     VMDEHKVTVVSYVPSLLNTVLADPRRRLGHHLRLVLIAGEALPAGLVNAFREVCHAEAA
                     NVYGPTETSVSCVIWPVPDRSDVTRVPIGRPLTGTRGYVLDPELRPVPAGVPGELYVGG
                     SGVARGYLARPGMTAERFVPDPFGTGGGRLYRTGDLVRWMPDGCLEFVGRADHQVKVR"
     CDS_motif       complement(22185..22313)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26935_0009"
                     /evalue="2.20E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="IEZ14_RS26935"
                     /protein_end="833"
                     /protein_start="790"
                     /score="51.9"
                     /tool="antismash"
                     /translation="TRGYVLDPELRPVPAGVPGELYVGGSGVARGYLARPGMTAERF"
     CDS_motif       complement(22731..22760)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26935_0008"
                     /evalue="1.70E+01"
                     /label="NRPS-E5"
                     /locus_tag="IEZ14_RS26935"
                     /protein_end="651"
                     /protein_start="641"
                     /score="-1.0"
                     /tool="antismash"
                     /translation="LGWMQRTFPI"
     CDS_motif       complement(22779..22835)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26935_0007"
                     /evalue="6.80E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="IEZ14_RS26935"
                     /protein_end="635"
                     /protein_start="616"
                     /score="27.8"
                     /tool="antismash"
                     /translation="YIICTSGSTGRPKGVMTTH"
     CDS_motif       complement(23034..23075)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26935_0006"
                     /evalue="4.30E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="IEZ14_RS26935"
                     /protein_end="550"
                     /protein_start="536"
                     /score="16.7"
                     /tool="antismash"
                     /translation="LAVVKAGGCYVPLD"
     CDS_motif       complement(23601..23723)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26935_0005"
                     /evalue="5.60E-20"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="IEZ14_RS26935"
                     /protein_end="361"
                     /protein_start="320"
                     /score="63.8"
                     /tool="antismash"
                     /translation="QKDLAAGRRYDYSPLAQVQRWSDVPGGTALFDSIVAYENYP"
     aSDomain        complement(23760..24659)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS26935_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="5.10E-107"
                     /label="IEZ14_RS26935_Condensation_DCL.1"
                     /locus_tag="IEZ14_RS26935"
                     /protein_end="308"
                     /protein_start="8"
                     /score="349.4"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLLLDG"
                     /tool="antismash"
                     /translation="EKVFPLTAMQQGMLLHSVGDPAAGFYVNQIVFTLRGPLDASRLRD
                     SWQWVADRHPALRTAFVWEGTDEPLQVVRTSVPVPWTELDWRAVSHEEREQELSGLLED
                     DRSRPFELARAPLVRMVLVRLTDEDWWLVLTFHHLLLDGWSVQLVVDDAFTRYRRADAD
                     GTEEAAPGPPHWEYVAWLHGQDPAAAERHWREHLAGFREPTPLSVGHPAARGEPGFGEI
                     TDVLPDELRARLEDLAKRRHLTLGTVVHGAWALLLSRYSGQRDVVFGSVVSTRPPQVPD
                     VERMVGLLSATLPIRVRVD"
     CDS_motif       complement(23772..23867)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26935_0004"
                     /evalue="3.90E-15"
                     /label="C5_DCL_263-294"
                     /locus_tag="IEZ14_RS26935"
                     /protein_end="304"
                     /protein_start="272"
                     /score="48.2"
                     /tool="antismash"
                     /translation="DVVFGSVVSTRPPQVPDVERMVGLLSATLPIR"
     CDS_motif       complement(23895..23936)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26935_0003"
                     /evalue="3.00E+01"
                     /label="C3_dual_135-156"
                     /locus_tag="IEZ14_RS26935"
                     /protein_end="263"
                     /protein_start="249"
                     /score="-1.8"
                     /tool="antismash"
                     /translation="HLTLGTVVHGAWAL"
     CDS_motif       complement(24189..24254)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26935_0002"
                     /evalue="1.60E-08"
                     /label="C3_DCL_135-156"
                     /locus_tag="IEZ14_RS26935"
                     /protein_end="165"
                     /protein_start="143"
                     /score="27.0"
                     /tool="antismash"
                     /translation="FHHLLLDGWSVQLVVDDAFTRY"
     CDS_motif       complement(24471..24590)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26935_0001"
                     /evalue="4.60E-19"
                     /label="C2_DCL_024-062"
                     /locus_tag="IEZ14_RS26935"
                     /protein_end="71"
                     /protein_start="31"
                     /score="60.7"
                     /tool="antismash"
                     /translation="GFYVNQIVFTLRGPLDASRLRDSWQWVADRHPALRTAFVW"
     aSDomain        complement(24597..24677)
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS26935_NRPS-COM_Nterm.1"
                     /evalue="1.90E-08"
                     /label="IEZ14_RS26935_NRPS-COM_Nterm.1"
                     /locus_tag="IEZ14_RS26935"
                     /protein_end="29"
                     /protein_start="2"
                     /score="25.4"
                     /tool="antismash"
                     /translation="IDNGEVEKVFPLTAMQQGMLLHSVGDP"
     gene            complement(24680..30550)
                     /locus_tag="IEZ14_RS26940"
                     /old_locus_tag="GCM10010177_54350"
     CDS             complement(24680..30550)
                     /NRPS_PKS="Domain: AMP-binding (254-668). E-value: 1.5e-99.
                     Score: 325.3. Matches aSDomain:
                     nrpspksdomains_IEZ14_RS26940_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (779-847). E-value: 2.7e-19. Score:
                     61.2. Matches aSDomain: nrpspksdomains_IEZ14_RS26940_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (869-1170). E-value:
                     2.8e-102. Score: 333.7. Matches aSDomain:
                     nrpspksdomains_IEZ14_RS26940_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1333-1734). E-value:
                     1.4e-111. Score: 364.9. Matches aSDomain:
                     nrpspksdomains_IEZ14_RS26940_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (1845-1910). E-value: 6e-21. Score:
                     66.4. Matches aSDomain: nrpspksdomains_IEZ14_RS26940_PCP.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF003417.0"
                     /locus_tag="IEZ14_RS26940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_54350"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_179832846.1"
                     /sec_met_domain="Condensation (E-value: 1.2e-68, bitscore:
                     225.4, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.6e-124, bitscore:
                     409.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.8e-11, bitscore:
                     37.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVPLVAFWREELSGAPEVLTLPTDRPRHAASRRTGRLPVEVPGET
                     LSSLRELAAAERTTPLVPLLAAFSVVVARWSGLTDIVVGSPMPTRADLSGRPSFREVVG
                     RLRRTCERVDAHSDLPFESLVEALALPPDPAHHPVFQVALTLDDEVLDAPVAPARGPAG
                     TSLDLAVRFTERENALSGALDYDTGLFDRDTAQRLAGSLRTLLAAAAADPDRPVAALPL
                     LTASERRTLAGWADGGPAPVTVDRPEDCLPALFEAQAARTPEAIAVSSGSERVSYAELN
                     ARANRLAHRLREHRSLGPGPGAEMFVGLMARRGPDFIAGMLATLKAGGAFVPLSPAQPA
                     DRLRYIIAQSGCGVVLGDAAGREALTGAMAAAPQDRRPVWIDIDPRAHLDRPAGDPPAR
                     CLPDAVAYVMFTSGTTGAPKGAGVLHRGLLNHMTAKISDLGMGPADVLAQNGPATFDVV
                     VWQCLTPLTIGGRVHVVPDEALEDPERLAEEVRSGGVSVLQAVPAAISMMLAGPAASRL
                     AGLRWLVPTGDALPGDLVRRWLDLHPAVPLLNTYGLTECSDDQCHAVIDAPPDGTSGPI
                     ATIGRPVPGMRAYVVDREMQPVPAGVVGELYLGGTGIGRGYAGRPGLTAERFVPDPFQR
                     GGGRLYRTGDLVRWARNGTLDFVGRADFQVKIRGFRVEPGEIEAALTRHPGVREAVVTV
                     REDHGPDSRRLVGYLVPAEAERPRPEELRGFAASRLPDYMVPAAFVLLEALPVTANGKI
                     DRQALPIPETVDGQPPEDSVPPRDDIERTLAGLWAEVLRTDRFGVFDNFFALSGNSILA
                     VRLLTRVQDVFGVDLGIAELFEEATVAGAASAVREALGRHEATVATPELRREPRDGGPL
                     PASFSQERLWVLEQLQPGQATYNVPVAVRLRCELDTARLRVALAELAGRHEVLRTSVTV
                     VDGRPFQTVHESVDVELKEIELDGSGPPAPSGGSADPLAGARDLLDAEARRLFDLGTAP
                     LWRACLIRLSEGDHVLGLTLHHLITDGWSGGVLLRDLLRLLASDTLAPLPVQFADFAAW
                     QRELLTSERQAELVRFWTDELAGAPQLLELPTDRPRPRVQAHRGARHDVEVPPALLAAM
                     RRLGAAEGATLFMTLLAGFAAVLSRWSGQSDVVVGAPVAGRPAADVEELAGFFANTLVL
                     RTDTSGRPSFRRLLDGVRRTCLRAYAHQEMPFERLVEELAPRRSMAHNPLFQVMLTLQA
                     AAPLDGTAGQAEELFPPDTGTAKFDLALYLVEDTDRLRGVFEYDVDLFTADTVERLTGH
                     LLTLLAAAVAEPDRPVATLPMLTAGEHDQIAEWNRTRRAHRRVRLPHLVAEQAAASPHA
                     LALGFGERRITYREFAAAVDRLAGRLRRAGVGPERVVGVCLHRGVELVVAVHAVLAAGG
                     AYLPLDPDHPASRRRFAVEDSGATVVLTSDDHADDLTGAGATLLRWDDGDLDTPVEAGA
                     PAFTGDGAEAGDELAYVIYTSGSTGRPKGVGISHRSLVNRLRWMQEAFPLGPQDRVLHK
                     TPFTFDVSVWELFWPLTAGAGLIVAEPGRHRDPDHLLELVTRADVQTVHFVPSMLNPFL
                     DRVRELGRPACLRRVICSGEPLPAELARRFAEVLPGVALHNLYGPTEATIDVTWHPCDP
                     AERTVPIGRPVSNTRAEVLDGEGQRVPVGVPGELCLGGVQVGRGYLNRPGTTAERFAPD
                     PFTGDGGRLYRTGDRVRRLPDGELEFLGRTDFQVKVRGLRIELGEIEAVLAEHPAVRDV
                     VVTTRRDGADTTRLVAHLVPAGDGSEVPVPRLREFLAARLPEYMVPSAFQWLASLPLTA
                     SGKVDRAALPAAEVTREQTGGRFVPPRDRAEKILADAWTRVLAVDRVGVFDNFFELGGD
                     SILSIMVVSRVAREGLHITPEQFFDKQTIADLARLARWSGPDRPGVPDASGDDRFPVTR
                     IDGDTFDYILSVMREQDRLSEGS"
     aSDomain        complement(24821..25015)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS26940_PCP.2"
                     /evalue="6.00E-21"
                     /label="IEZ14_RS26940_PCP.2"
                     /locus_tag="IEZ14_RS26940"
                     /protein_end="1910"
                     /protein_start="1845"
                     /score="66.4"
                     /tool="antismash"
                     /translation="EKILADAWTRVLAVDRVGVFDNFFELGGDSILSIMVVSRVAREGL
                     HITPEQFFDKQTIADLARLA"
     aSModule        complement(24821..27943)
                     /complete
                     /domains="nrpspksdomains_IEZ14_RS26940_Condensation_LCL.1"
                     /domains="nrpspksdomains_IEZ14_RS26940_AMP-binding.2"
                     /domains="nrpspksdomains_IEZ14_RS26940_PCP.2"
                     /locus_tags="IEZ14_RS26940"
                     /monomer_pairings="Ser -> Ser"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(25076..25102)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26940_0018"
                     /evalue="4.30E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="IEZ14_RS26940"
                     /protein_end="1825"
                     /protein_start="1816"
                     /score="4.0"
                     /tool="antismash"
                     /translation="GKVDRAALP"
     CDS_motif       complement(25319..25384)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26940_0017"
                     /evalue="4.20E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="IEZ14_RS26940"
                     /protein_end="1744"
                     /protein_start="1722"
                     /score="34.8"
                     /tool="antismash"
                     /translation="FLGRTDFQVKVRGLRIELGEIE"
     aSDomain        complement(25349..26551)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS26940_AMP-binding.2"
                     /evalue="1.40E-111"
                     /label="IEZ14_RS26940_AMP-binding.2"
                     /locus_tag="IEZ14_RS26940"
                     /protein_end="1734"
                     /protein_start="1333"
                     /score="364.9"
                     /specificity="substrate consensus: Ser"
                     /tool="antismash"
                     /translation="AEQAAASPHALALGFGERRITYREFAAAVDRLAGRLRRAGVGPER
                     VVGVCLHRGVELVVAVHAVLAAGGAYLPLDPDHPASRRRFAVEDSGATVVLTSDDHADD
                     LTGAGATLLRWDDGDLDTPVEAGAPAFTGDGAEAGDELAYVIYTSGSTGRPKGVGISHR
                     SLVNRLRWMQEAFPLGPQDRVLHKTPFTFDVSVWELFWPLTAGAGLIVAEPGRHRDPDH
                     LLELVTRADVQTVHFVPSMLNPFLDRVRELGRPACLRRVICSGEPLPAELARRFAEVLP
                     GVALHNLYGPTEATIDVTWHPCDPAERTVPIGRPVSNTRAEVLDGEGQRVPVGVPGELC
                     LGGVQVGRGYLNRPGTTAERFAPDPFTGDGGRLYRTGDRVRRLPDGELEFLGRTDFQVK
                     VR"
     CDS_motif       complement(25469..25558)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26940_0016"
                     /evalue="4.50E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="IEZ14_RS26940"
                     /protein_end="1694"
                     /protein_start="1664"
                     /score="50.9"
                     /tool="antismash"
                     /translation="PVGVPGELCLGGVQVGRGYLNRPGTTAERF"
     CDS_motif       complement(26066..26125)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26940_0015"
                     /evalue="6.60E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="IEZ14_RS26940"
                     /protein_end="1495"
                     /protein_start="1475"
                     /score="30.9"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVGISH"
     CDS_motif       complement(26327..26365)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26940_0014"
                     /evalue="6.70E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="IEZ14_RS26940"
                     /protein_end="1408"
                     /protein_start="1395"
                     /score="13.1"
                     /tool="antismash"
                     /translation="AVLAAGGAYLPLD"
     CDS_motif       complement(26882..27001)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26940_0013"
                     /evalue="1.10E-22"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="IEZ14_RS26940"
                     /protein_end="1223"
                     /protein_start="1183"
                     /score="72.5"
                     /tool="antismash"
                     /translation="RRTCLRAYAHQEMPFERLVEELAPRRSMAHNPLFQVMLTL"
     aSDomain        complement(27041..27943)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS26940_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="2.80E-102"
                     /label="IEZ14_RS26940_Condensation_LCL.1"
                     /locus_tag="IEZ14_RS26940"
                     /protein_end="1170"
                     /protein_start="869"
                     /score="333.7"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLITDG"
                     /tool="antismash"
                     /translation="PLPASFSQERLWVLEQLQPGQATYNVPVAVRLRCELDTARLRVAL
                     AELAGRHEVLRTSVTVVDGRPFQTVHESVDVELKEIELDGSGPPAPSGGSADPLAGARD
                     LLDAEARRLFDLGTAPLWRACLIRLSEGDHVLGLTLHHLITDGWSGGVLLRDLLRLLAS
                     DTLAPLPVQFADFAAWQRELLTSERQAELVRFWTDELAGAPQLLELPTDRPRPRVQAHR
                     GARHDVEVPPALLAAMRRLGAAEGATLFMTLLAGFAAVLSRWSGQSDVVVGAPVAGRPA
                     ADVEELAGFFANTLVLRTDT"
     CDS_motif       complement(27050..27139)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26940_0012"
                     /evalue="3.30E-14"
                     /label="C5_LCL_267-296"
                     /locus_tag="IEZ14_RS26940"
                     /protein_end="1167"
                     /protein_start="1137"
                     /score="45.2"
                     /tool="antismash"
                     /translation="DVVVGAPVAGRPAADVEELAGFFANTLVLR"
     CDS_motif       complement(27149..27202)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26940_0011"
                     /evalue="2.70E-04"
                     /label="Cy4"
                     /locus_tag="IEZ14_RS26940"
                     /protein_end="1134"
                     /protein_start="1116"
                     /score="14.0"
                     /tool="antismash"
                     /translation="TLFMTLLAGFAAVLSRWS"
     CDS_motif       complement(27392..27430)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26940_0010"
                     /evalue="5.20E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="IEZ14_RS26940"
                     /protein_end="1053"
                     /protein_start="1040"
                     /score="15.8"
                     /tool="antismash"
                     /translation="QFADFAAWQRELL"
     CDS_motif       complement(27464..27526)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26940_0009"
                     /evalue="2.00E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="IEZ14_RS26940"
                     /protein_end="1029"
                     /protein_start="1008"
                     /score="26.7"
                     /tool="antismash"
                     /translation="LHHLITDGWSGGVLLRDLLRL"
     CDS_motif       complement(27770..27880)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26940_0008"
                     /evalue="6.20E-13"
                     /label="C2_LCL_024-062"
                     /locus_tag="IEZ14_RS26940"
                     /protein_end="927"
                     /protein_start="890"
                     /score="41.1"
                     /tool="antismash"
                     /translation="ATYNVPVAVRLRCELDTARLRVALAELAGRHEVLRTS"
     aSDomain        complement(28010..28213)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS26940_PCP.1"
                     /evalue="2.70E-19"
                     /label="IEZ14_RS26940_PCP.1"
                     /locus_tag="IEZ14_RS26940"
                     /protein_end="847"
                     /protein_start="779"
                     /score="61.2"
                     /tool="antismash"
                     /translation="ERTLAGLWAEVLRTDRFGVFDNFFALSGNSILAVRLLTRVQDVFG
                     VDLGIAELFEEATVAGAASAVRE"
     aSModule        complement(28010..29788)
                     /complete
                     /domains="nrpspksdomains_IEZ14_RS26940_AMP-binding.1"
                     /domains="nrpspksdomains_IEZ14_RS26940_PCP.1"
                     /locus_tags="IEZ14_RS26940"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(28274..28300)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26940_0007"
                     /evalue="2.10E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="IEZ14_RS26940"
                     /protein_end="759"
                     /protein_start="750"
                     /score="4.8"
                     /tool="antismash"
                     /translation="GKIDRQALP"
     CDS_motif       complement(28517..28582)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26940_0006"
                     /evalue="3.00E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="IEZ14_RS26940"
                     /protein_end="678"
                     /protein_start="656"
                     /score="38.4"
                     /tool="antismash"
                     /translation="FVGRADFQVKIRGFRVEPGEIE"
     aSDomain        complement(28547..29788)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS26940_AMP-binding.1"
                     /evalue="1.50E-99"
                     /label="IEZ14_RS26940_AMP-binding.1"
                     /locus_tag="IEZ14_RS26940"
                     /protein_end="668"
                     /protein_start="254"
                     /score="325.3"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEAQAARTPEAIAVSSGSERVSYAELNARANRLAHRLREHRSLGP
                     GPGAEMFVGLMARRGPDFIAGMLATLKAGGAFVPLSPAQPADRLRYIIAQSGCGVVLGD
                     AAGREALTGAMAAAPQDRRPVWIDIDPRAHLDRPAGDPPARCLPDAVAYVMFTSGTTGA
                     PKGAGVLHRGLLNHMTAKISDLGMGPADVLAQNGPATFDVVVWQCLTPLTIGGRVHVVP
                     DEALEDPERLAEEVRSGGVSVLQAVPAAISMMLAGPAASRLAGLRWLVPTGDALPGDLV
                     RRWLDLHPAVPLLNTYGLTECSDDQCHAVIDAPPDGTSGPIATIGRPVPGMRAYVVDRE
                     MQPVPAGVVGELYLGGTGIGRGYAGRPGLTAERFVPDPFQRGGGRLYRTGDLVRWARNG
                     TLDFVGRADFQVKIR"
     CDS_motif       complement(28667..28756)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26940_0005"
                     /evalue="1.00E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="IEZ14_RS26940"
                     /protein_end="628"
                     /protein_start="598"
                     /score="43.4"
                     /tool="antismash"
                     /translation="PAGVVGELYLGGTGIGRGYAGRPGLTAERF"
     CDS_motif       complement(29276..29335)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26940_0004"
                     /evalue="7.80E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="IEZ14_RS26940"
                     /protein_end="425"
                     /protein_start="405"
                     /score="21.6"
                     /tool="antismash"
                     /translation="AYVMFTSGTTGAPKGAGVLH"
     CDS_motif       complement(29549..29587)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26940_0003"
                     /evalue="4.10E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="IEZ14_RS26940"
                     /protein_end="334"
                     /protein_start="321"
                     /score="13.8"
                     /tool="antismash"
                     /translation="LATLKAGGAFVPL"
     CDS_motif       complement(30113..30232)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26940_0002"
                     /evalue="3.40E-12"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="IEZ14_RS26940"
                     /protein_end="146"
                     /protein_start="106"
                     /score="38.7"
                     /tool="antismash"
                     /translation="RRTCERVDAHSDLPFESLVEALALPPDPAHHPVFQVALTL"
     CDS_motif       complement(30323..30361)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26940_0001"
                     /evalue="3.80E-03"
                     /label="Cy4"
                     /locus_tag="IEZ14_RS26940"
                     /protein_end="76"
                     /protein_start="63"
                     /score="10.4"
                     /tool="antismash"
                     /translation="LLAAFSVVVARWS"
     gene            complement(30610..31596)
                     /gene="sbnA"
                     /locus_tag="IEZ14_RS26945"
                     /old_locus_tag="GCM10010177_54360"
     CDS             complement(30610..31596)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="sbnA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017621975.1"
                     /locus_tag="IEZ14_RS26945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_54360"
                     /product="2,3-diaminopropionate biosynthesis protein SbnA"
                     /protein_id="WP_229810442.1"
                     /sec_met_domain="PALP (E-value: 9.8e-66, bitscore: 216.1,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHESVVSCIGRTPIVALRRLFDDPGVEVLAKLEMLNPGGSVKDR
                     PARHIIEEGLRNGAIAPDSHLVESTSGNFGIALAMVCRIYDLALTVVVDPNITATNLQL
                     LRRYGANVDMVSEGDGSGGYLEQRLRRVREIVGAVPGSVWVNQYANRLNWQAHAETTGK
                     EILADVDGPLDCVVMAVSTTGTIHGVARALRVAYPRLRVVAVDAVGSVIFGHPPAPRRV
                     PGIGAGRVPELLCRDEIDDVVLVDDDQAVQGCHELLRSEGILAGGSSGAVVAGLWQLLP
                     RLPRPVRVLTLLPDRGERYLDLLYADAPAEPRFDWSSSPPRRPLSRS"
     gene            complement(31593..34226)
                     /locus_tag="IEZ14_RS26950"
                     /old_locus_tag="GCM10010177_54370"
     CDS             complement(31593..34226)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_LCL (54-355). E-value:
                     6e-101. Score: 329.3. Matches aSDomain:
                     nrpspksdomains_IEZ14_RS26950_Condensation_LCL.1"
                     /NRPS_PKS="Domain: PCP (534-603). E-value: 2.5e-20. Score:
                     64.5. Matches aSDomain: nrpspksdomains_IEZ14_RS26950_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (623-848). E-value:
                     9.4e-21. Score: 67.2. Matches aSDomain:
                     nrpspksdomains_IEZ14_RS26950_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012873.5"
                     /locus_tag="IEZ14_RS26950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_54370"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_179832844.1"
                     /sec_met_domain="Condensation (E-value: 2.4e-71, bitscore:
                     234.2, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.3e-11, bitscore:
                     37.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 2.2e-17, bitscore:
                     58.0, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEATSGPSDRAERLAALSPRARELVLRRMRGPARDGAAATGPAD
                     PRPVPRTGAPLPASFSQERLWLLDRLRPDSAAYVVSTAGRLRGDLDVDRLRAGLADLTA
                     RHEILRTSLAWTGDRTAQIVHDSVTVPWEMTDLSAVSDPRADAERILAADVERGFDLTA
                     APLWRARLVRMGPRDHLFGVAMHHTITDAWSVGVLLSELGRLYTASRRDPAPERPVLPP
                     LPLQYGDFAVWQRERLTDDLVAGLTGFWKEELAGAPELLALPTDRPRPQVRSGRGARHD
                     FEVPGDLLRAARELSGSTDVTLFMALLAAFVTVLSRWSGETDVVVGTPVAGRHHPDLEG
                     LIGFFVNSVVVRTDLSGGPSFRRLLHHVRRQSLRAFEHQDLPFEKLVEHLAPTRDTAYN
                     PLFQVNFGFGNVPRGHLDLPGTVAEPVAVPSGAGAKFDLSLYLNEDRGRLAGTFEYATD
                     IFDAATIERLAGYLVEVLAAVTADPDLPIAHLPDPRPGQRPGTPSGSTPETGDPGEPPA
                     PSLWPASPGFVEPRDRWERYVAQVWSEVLGVTPIGAHDEFFELGGSSMPGMLVVDRLCR
                     LTGRSVTLHDLYATRTVEALADWIRSGETISPDPQFVVELQPGGPRAPLFFLHAVLGEL
                     YHYFELARALGTGRALYGVQNDGFFHGGADPGVLTMEQMADRYAEEVRRVHPEGPYHLC
                     GFSGAGRFALAVADRLHAAGDRVGTVALLDTAPLTDAPPAPDRAFILAGWLLFSPPEDE
                     LRGLDPRAQLQRVLEAGKRAGDLPPDVEPAEFESFCRRLELNARAISPYRPSYPGTVTL
                     LTQRDRTDRDLPAEWARFPIGGLKVEEIDAGSHMEFVYGPAVAEVARRLEACLDEPAHG
                     DPGADR"
     aSDomain        complement(31683..32357)
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS26950_Thioesterase.1"
                     /evalue="9.40E-21"
                     /label="IEZ14_RS26950_Thioesterase.1"
                     /locus_tag="IEZ14_RS26950"
                     /protein_end="848"
                     /protein_start="623"
                     /score="67.2"
                     /tool="antismash"
                     /translation="PLFFLHAVLGELYHYFELARALGTGRALYGVQNDGFFHGGADPGV
                     LTMEQMADRYAEEVRRVHPEGPYHLCGFSGAGRFALAVADRLHAAGDRVGTVALLDTAP
                     LTDAPPAPDRAFILAGWLLFSPPEDELRGLDPRAQLQRVLEAGKRAGDLPPDVEPAEFE
                     SFCRRLELNARAISPYRPSYPGTVTLLTQRDRTDRDLPAEWARFPIGGLKVEEIDAGSH
                     MEF"
     aSModule        complement(31683..34064)
                     /domains="nrpspksdomains_IEZ14_RS26950_Condensation_LCL.1"
                     /domains="nrpspksdomains_IEZ14_RS26950_PCP.1"
                     /domains="nrpspksdomains_IEZ14_RS26950_Thioesterase.1"
                     /final_module
                     /incomplete
                     /locus_tags="IEZ14_RS26950"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(32097..32171)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26950_0007"
                     /evalue="2.90E-05"
                     /label="NRPS-te1"
                     /locus_tag="IEZ14_RS26950"
                     /protein_end="710"
                     /protein_start="685"
                     /score="16.6"
                     /tool="antismash"
                     /translation="HPEGPYHLCGFSGAGRFALAVADRL"
     aSDomain        complement(32418..32624)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS26950_PCP.1"
                     /evalue="2.50E-20"
                     /label="IEZ14_RS26950_PCP.1"
                     /locus_tag="IEZ14_RS26950"
                     /protein_end="603"
                     /protein_start="534"
                     /score="64.5"
                     /tool="antismash"
                     /translation="ERYVAQVWSEVLGVTPIGAHDEFFELGGSSMPGMLVVDRLCRLTG
                     RSVTLHDLYATRTVEALADWIRSG"
     CDS_motif       complement(33006..33122)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26950_0006"
                     /evalue="5.80E-20"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="IEZ14_RS26950"
                     /protein_end="407"
                     /protein_start="368"
                     /score="63.7"
                     /tool="antismash"
                     /translation="RRQSLRAFEHQDLPFEKLVEHLAPTRDTAYNPLFQVNFG"
     aSDomain        complement(33162..34064)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS26950_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="6.00E-101"
                     /label="IEZ14_RS26950_Condensation_LCL.1"
                     /locus_tag="IEZ14_RS26950"
                     /protein_end="355"
                     /protein_start="54"
                     /score="329.3"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHTITDA"
                     /tool="antismash"
                     /translation="PLPASFSQERLWLLDRLRPDSAAYVVSTAGRLRGDLDVDRLRAGL
                     ADLTARHEILRTSLAWTGDRTAQIVHDSVTVPWEMTDLSAVSDPRADAERILAADVERG
                     FDLTAAPLWRARLVRMGPRDHLFGVAMHHTITDAWSVGVLLSELGRLYTASRRDPAPER
                     PVLPPLPLQYGDFAVWQRERLTDDLVAGLTGFWKEELAGAPELLALPTDRPRPQVRSGR
                     GARHDFEVPGDLLRAARELSGSTDVTLFMALLAAFVTVLSRWSGETDVVVGTPVAGRHH
                     PDLEGLIGFFVNSVVVRTDL"
     CDS_motif       complement(33171..33260)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26950_0005"
                     /evalue="3.00E-17"
                     /label="C5_LCL_267-296"
                     /locus_tag="IEZ14_RS26950"
                     /protein_end="352"
                     /protein_start="322"
                     /score="54.9"
                     /tool="antismash"
                     /translation="DVVVGTPVAGRHHPDLEGLIGFFVNSVVVR"
     CDS_motif       complement(33270..33326)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26950_0004"
                     /evalue="1.10E-05"
                     /label="Cy4"
                     /locus_tag="IEZ14_RS26950"
                     /protein_end="319"
                     /protein_start="300"
                     /score="18.3"
                     /tool="antismash"
                     /translation="VTLFMALLAAFVTVLSRWS"
     CDS_motif       complement(33513..33551)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26950_0003"
                     /evalue="3.00E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="IEZ14_RS26950"
                     /protein_end="238"
                     /protein_start="225"
                     /score="19.6"
                     /tool="antismash"
                     /translation="QYGDFAVWQRERL"
     CDS_motif       complement(33609..33674)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26950_0002"
                     /evalue="3.50E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="IEZ14_RS26950"
                     /protein_end="206"
                     /protein_start="184"
                     /score="29.1"
                     /tool="antismash"
                     /translation="MHHTITDAWSVGVLLSELGRLY"
     CDS_motif       complement(33891..34001)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26950_0001"
                     /evalue="5.10E-14"
                     /label="C2_LCL_024-062"
                     /locus_tag="IEZ14_RS26950"
                     /protein_end="112"
                     /protein_start="75"
                     /score="44.6"
                     /tool="antismash"
                     /translation="AAYVVSTAGRLRGDLDVDRLRAGLADLTARHEILRTS"
     misc_feature    complement(33942..33944)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(34219..>34518)
                     /locus_tag="IEZ14_RS26955"
     CDS             complement(34219..>34518)
                     /NRPS_PKS="Domain: PCP (0-64). E-value: 7.9e-24. Score:
                     75.7. Matches aSDomain: nrpspksdomains_IEZ14_RS26955_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012759.5"
                     /locus_tag="IEZ14_RS26955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphopantetheine-binding protein"
                     /protein_id="WP_189269950.1"
                     /sec_met_domain="PP-binding (E-value: 8e-16, bitscore:
                     52.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="AGLWSEVLGVSEIGVHDNFFTLGGDSLMAVRVVGRIREAFPADYT
                     LPELFAAPSISGCAAAVERLLSDAADLDALVDEVAGLSDEEIAARLAEGEKSHE"
     aSDomain        complement(34324..34515)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS26955_PCP.1"
                     /evalue="7.90E-24"
                     /label="IEZ14_RS26955_PCP.1"
                     /locus_tag="IEZ14_RS26955"
                     /protein_end="64"
                     /protein_start="0"
                     /score="75.7"
                     /tool="antismash"
                     /translation="AGLWSEVLGVSEIGVHDNFFTLGGDSLMAVRVVGRIREAFPADYT
                     LPELFAAPSISGCAAAVER"
     CDS_motif       complement(34435..34464)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS26955_0001"
                     /evalue="1.10E-03"
                     /label="PCP_mC"
                     /locus_tag="IEZ14_RS26955"
                     /protein_end="27"
                     /protein_start="17"
                     /score="12.2"
                     /tool="antismash"
                     /translation="NFFTLGGDSL"
ORIGIN
        1 ggtcgcccgg gtggacgaga cccccgtgca ccgctggcac atcgccgacc cggccaaccc
       61 tgaccggccg ccggtcgaga tcgcctaccc ggcggcgggc accccgaacg ccctggtgtc
      121 cctggtgctg ctgaaggtgg acggcgggcg gatcgcggtg gactgggacc gcggcatgtt
      181 cccctacctc gtgaccgccg tctgggaccg gcacggcctg ctgatcgtcg tgcagccccg
      241 cgaccagcgc tcccagcggg tgctgcgggt cgatccgacc aacggcgaga cggtgctgct
      301 gcacaccgag cacgaccccg tctggacgga ggtcatcccc ggcctgcccg tccgcacgca
      361 cggcggcgcc ctggtgtggg ccaccgagga cgccgagacc gacacccgcc ggctcaccgt
      421 cgcgggcgag cccgtcacgc ccggcggcct gcagctgcgt tccgtcctcg gcgtggacgg
      481 cgagtcgatc ctgttcaccg cctgggagga gcccaccgag gtccacctct actcctacga
      541 gggcggcgag gtgacccggc tcagcgaggg gccgggcgtc ttcggcggca cccggtcggg
      601 ggacgtcacc gtcgtctcgg gcgcgcggct ggaccgcctc ggctcgcagg ccgaggtgcg
      661 cacgccgacc gcggtccacc ccgtcgcctc gttcgccgag accccggtga tcaccccgcg
      721 ggtggagctg ctgcgctccg gcgaccgcga gctgcgcacc gccgtcgtgc tgcccaccgg
      781 ctgggagccg gggcacggcc gcctgcccgt cctgatggac ccctacggcg gcccgcacgc
      841 gcagcgcgtg ctcgccgtcc agcgctccta ctgcgaggcg cagtggctcg ccgaccaggg
      901 cttcgccgtc gtgatcgcgg acggtcgcgg cacccccgga cgcggccccg cctgggagcg
      961 cgccgtgcgc ggcgacttcg tcggccccgt cctggatgac cagatcagcg cgctgatcga
     1021 ggcggcccgc aagcaccccg cggccctcga cctcgaccgc gtcggcatcc gcggctggtc
     1081 gttcggcggc tggctcgcgg ccctggccgt catgctccgc ccggacgtct tccacgcggg
     1141 cgtcgcgggc gcgccggtca ccgactggcg cctgtacgac acccactaca ccgagcggta
     1201 cctgggccac cccgacgagg agccggagaa ctacgccgac aactccctcc tcggcaaggc
     1261 cgccgacctg aagcggccac tgatgatcat ccacggcctg gcggacgaca acgtggtggc
     1321 cgcccacacc ctgcgcctgt cctcggccct cttggccgca ggccgccccc acaccgtcct
     1381 ccccctgtcg ggcgtcaccc acatgacccc gcaagaagtg gtcgccgaaa acctcctcca
     1441 catccaggtc cacttcctca aagaatccct aggcgcacag tgaccgcagg aggaggcttt
     1501 cagcttctcc aggaggccca aagggctgcg taggagccct gtgccgctag aagttcttcg
     1561 tgggtgccca gttcggtgat gcggccgtcc tccaccacgg ccacgcggtc ggcgtcgtgg
     1621 gcggtgtgga ggcggtgggc gatggcgacg acggtccggc cgtccaggac ggcggccagc
     1681 gagcgttcca ggcggcgggc ggcgcgcggg tcgaggaggg acgtcgcctc gtccaggacg
     1741 agcgtgtgcg ggtcggcgag gacgagccgg gccagggcga gctgctgggc ctgggcgggc
     1801 gacagggtct cgccgcccga gccgacgacg gcgtcgaggc cggggccgtc ccagtcgacg
     1861 gcggccagga cctggcggat gtcgtcgtcg gaggcgccct cgcgggccat cacgaggttc
     1921 tcgcggaggg tgccgcggaa cacgtggtgc tcctgggtga ccagcgcgac atggccgcga
     1981 aggtcgtcca gggtcagctc gaccaggggg acgccgccgc ccgcgcccac ggtgaccgcg
     2041 cccgcgcgcg ggccgtcgac gccggcgagc agacggccga gcgtcgactt gcccgcgccg
     2101 ctgggcccga ccatcgccag gcgctcgccc ggccgcaggt cgaggtccac gccgtgcagg
     2161 acgtcgtggc ctcggcggta ggagtagtgg acgtcgcgcg ccgcgatccg ctcgccggtg
     2221 ggccgggccc cgttcggcgc gcggtcgggc gggacgttgc cgacgccgag cagccgggcc
     2281 agggacgcgc cgccgagctg gagctcgtcc agccactgca tgagcgtgtc caccggctcg
     2341 atgagctgct gggcgtacag ggtcgcggcg gtcacctgcg cgagcgtcgc catgccgttg
     2401 atgtagagca ggccgccgac gagcagcgtc gacacgacgg gtaggacgaa gctcatctcc
     2461 atcaccggga acagcaccgt gcgcagccgc agggtgtacc gctccacctt gtaggacgcc
     2521 gcgatgtcgg cgtcgccgcg ctcgtgccgg cgctcggcga gcccgagggc ctccacggtc
     2581 cgggcgccct ggacggtctc ggtcagcccg tcggcgatgc gcgcccacga cgcgttctcc
     2641 cgcaggtagc cgttgtgggc gcggggcagg taccagcgca tcaccgccac cagcaacggc
     2701 accgcgacca gggcgggcag cgcgacgagc gggccgttca gcatcagcgc tgcgacggtg
     2761 aacccgccca cgacgacggc gacgagggtc tccggcatcg cgtaccggac ggaggtgctc
     2821 agcgtgtcca cgtcgcggga ggcgcgggtg accaggtcgc cggtgcccgc gcgctcgacc
     2881 gtggacagcg gcagggccat gacgcggtcg acgaactcct cgcggagctc ggccagcacc
     2941 cgctcgccca gcttcgccga cgccaggtag gcgtaccgga tcagcacgct ctggacgatc
     3001 acgaacccgg cgatggccag cccggtggtg tcgatgtcgg cgccgccgtc gcggacgccc
     3061 tccaccagcg agccgagcag ccgcggcgtg acgagcccgg tcagggcggc cagcgcgtgc
     3121 agggccagca ctccggcgag gtcgcgcggg tgccggagga cgagccgccg cgcataggcc
     3181 cgcacctgcg cgggcgtcgc gacgggcaga agctcggcgc tcacgttccc gccctttccg
     3241 cggtctcgcc tcgggtgacg gtcgccgcgt agcgcggctc ggcgtccagc agttcccggt
     3301 gggtcccctc cgcgacgacc aggccgtcgc ggacgaaggc gacgtggtcg gcgcggtcca
     3361 gcatcagcgg gctcgtcgtg cacaccacgg tggtgcggcc cgcgcgcgct tcgccgagcc
     3421 tgccggcgat gcgcgcctcg gtgtgcgcgt ccaccgcgct ggtcggctcc acgaggacga
     3481 ggacgtcggg gtcggcggcg agcgccctgg ccaggcggag gcgctgctgc tggccgccgg
     3541 agaactcccg tccggcctcg gccacgtgcg cgtcgagccc ggccgagtcg acgacgtcct
     3601 cggcgcaggc ggcgcggacc gccgcccgga gcacggcctc gcccgcgccg ggcgcgagcg
     3661 actcggccag cgggccggag aacagccggt cctcgttgac cgcgaccagg atccgcttcc
     3721 ggacgtcctc gaccgcgcgc agcgggacgc cgccgaagtc gacctcgccg ctctcgtacc
     3781 ggccgaggcg gtcggcgacg gcctgcgcgt cgcgcggatc ggccgcggcg atcgcggtga
     3841 cccggcccgg ccgcacgacc agccccgagg cgatgtcgac cagctcggcg tgcgccgccg
     3901 gacgggccgt cccggtggcg ggcagctcgg ggtcgagccg cagcagcgcg gtgacccggc
     3961 ccgccgccac cagccccttg gtgatcttgc tggcggcctc gccgagggtc ttcagcggga
     4021 cgatcaggaa caccgcgtac ccgtagaacg cgaccagctc gccgacgccg atctcccccc
     4081 gcgcggcgaa ccgggcgccg gcccaggtga ccagcgcgat cagcaggccg ggcagcagca
     4141 cctcggcgcc gttcatccgc gtctcggccc gcgcgaccgc cacccccgcc ccgcgcaccc
     4201 gctgcgactc ggcgcggtag cggccggagt acagcgcctc gccgccgatg ccccgcagca
     4261 cccgcagccc cgcgaccagg tcggtggcgt gcgtggtcag ctcgccgacc agctcgcggt
     4321 gcgcctgctc ccgctcgcgg taggggcgca gcagcggcgc cgcggccacc aggatcagcg
     4381 ggacgccgac cagcacgatc aggccgagcg gcggcgacgt cgacagcagg atgccggcca
     4441 cgacgacgat cgcgaccacg gcgcccgacc cgcgcgcgac gatgtcgatg gtgtcgccga
     4501 tgtgcgacac gtcggagagg ccgacgctca ccacctcgcc ggcgctcagc cgcttcggca
     4561 gcgtcgagcc gaggcgggtg gactgccggg tgacgagctg gacggtccgg tacgcggcgg
     4621 aaagccagtt gaacacggcg caccggtgcc ggagcacgcc cgtcacggcc tgcgccacgc
     4681 cgaggccgag caggacggcg gcccatgtca cgagggcgcc ctcgtcccgc gccgcgacgc
     4741 cgtcgccgat ggcgcggccg agcgcggcgg gcatgagggc ctggctgagc atccaggcca
     4801 cgccgaggag ggcgcccgcg gtcacgcttc gccactggac gcgcagcagc gagagcaggt
     4861 agcgcgcggg ggatccgcga tcggcgcggg aggcgctcca gggatcgagg gacgtcgttc
     4921 gccctcgcgc aacgtggtcg gggccgccag gatctttcac cggcaacggc ttcacgcgac
     4981 gaaggttatg cagcggaacc cttggcgcac gactggtttt tcagcagcgg aaactggttt
     5041 cggcccgtcc ggaaacaccg acaaaggcgg gctcgggggg tgcgcccgga cgctgggaca
     5101 cgctaaggtc gtcaccgtac ggagcgatgc ttcctccgct ccatgagccg ggacacatgg
     5161 cggctaggcc cacgccgctg ccccggcgcg gcccgtaccg ttccccgcta ccgcagggac
     5221 gagcgggacg acgcggtcgt tgccagtgcc gtcgccagcc cgacattccg gaagccctgt
     5281 gagcaccatc agtcaccaga cgcatcccct cacgccaggt accgaggaca ggatcgagct
     5341 gctcctcatc gacgacgacc ccaccgacgt gctcatggtg gagaagatgc tcgccgacag
     5401 cggcctggac gcggggatca ccgtcgcgag cgacctggac gccgcgaggc gcatgctgac
     5461 gcggcgcacc cagtgcatca tcgtcgacct ctccacgccc gacatcgacc ggctggaggg
     5521 gctgcggcgg gtgctggcgc tgtccggccc ggccgccgtc gtcgtgctga ccggcctgga
     5581 cgacggccgc ctcggcgtcc aggcggtcgc cgcgggcgcc gaggactacc tggtcaagca
     5641 ggaggtcgac gggccgctgc tggcccgcgc gatccgctat gccatagagc gcaagcgctc
     5701 ggaggagacc gagcggcggc tcgtcgaggc ccgcatcctc ggccgcgaga acgcccggct
     5761 ggagcgcggc ctgctgccgg tcccgctgat cgaggacccg acgctgcgtc accacacccg
     5821 ctaccggccc ggccggcggc gggcgctgct cggcggcgac ttctacgaca ccgtgcagac
     5881 cgagggcggc gccgtccacc tggtgatcgg ggacgtctgc ggccacggcc ccgacgaggc
     5941 ggccctcggc gtccagctcc gcatggcgtg gcggacgctc gtcctggccg ggcacaccgg
     6001 cgagcagctg ctcggcaccc tggacaccgt cctcgggcac gagcggcgca gcgaggagat
     6061 cttcaccacc ctctgcatgg tcacgatcgc gccgtcccgg cggaccgccc ggatgcacct
     6121 cgccggccac cccgcgccgc tgttgttccg cggggcgccg ggagcgggcg gcgaggtcgc
     6181 ggcgctcccc gactacgccc acggcccggc gctcggcctg gtgcccggcg ccgagtggcc
     6241 gaccaccgag atcgatctcg gcgagtcctg gggcctgatg ctctacaccg acggcctgat
     6301 cgagggccgg atcggcgagg gctcggaccg gctcggcacc gacggcctgg tcggcctggc
     6361 ccgcaccgcg cgcgcccggg gcgcggccgg acggtcgctg atcgacgcgc tggtggccga
     6421 ggtggagcgg ctcaacggcg acgccctgac cgacgacctc gccgtgctgc tgctgtcgcg
     6481 gcaggccgaa acggaccggc cagggcgctg accacaagcc cctgacctcc gtcaatgtcg
     6541 cctgagtcac tcccaggcag agttcccgca ccccctgtga agtccctcac gcgcaccggt
     6601 gtcacggaac ggacacaagc cgcgtgcggc gtgtgttcat agcctgcggc tatcgccaca
     6661 agtgcgctca tgacttggaa agaatcgccg aaccggacat agcgtgcagg tcgtggctat
     6721 agcgatacct gcgatctacc gatcgaccgt cggcaagaag gccgtgatgg ccgtcaccgg
     6781 cggcatcctc gtgctgtacc tggtcgcgca catgatcggg aacctgaaga tcttcctcgg
     6841 cgcggaggag ttcaaccact acgcgcactg gctgcgcacg atgggcgagc ccgcggtgcc
     6901 gcgccggacg gtgctgacga tcatcgagct ggtgctcggc gcctcggtcg tgctgcacat
     6961 gtggtcggcg gtgtcgctcg gcaagcgcgc ggcgcacgcg cgtccggtga agtaccagtc
     7021 gaagaagaag tcgcacgcgc agggctacgc cgtccgcacc atgcggtacg gcggcgtcat
     7081 catcgccgtc tacatcatct ggcacctgct ggacctcacg ttcttcgtcg tgaaccccaa
     7141 gggcgccgac gccaccccct accagcggat ggtcgccgac ttcgacccgt cccgctggta
     7201 catcacggtc tggtacgtcg tcgcggtcct gctcgtcggc ctccacctca accacggcat
     7261 ctggagcgcg ttccagacgc tggggctccg cagcccgcgc agccacaacg ccctgagggg
     7321 cctcgccgcg accaccgccg cgctcgtcac gctcggcttc gtcgccgtcc ccgtctccat
     7381 cacgttcgga tgggtgagct gatcccatga cagacggctt ctacaagtcc ggcgagccga
     7441 tcgccgacgc caaggctccg gcgggcgcca tcgaggagcg ctggacgacc cgcaagttcg
     7501 aggccaagca ggtcaacccg gccaacaagc gcaagaagaa gatcatcatc atcggcacgg
     7561 ggctggccgg cggatcggcc ggcgccaccc tcggcgaggc cggctaccac gtccagcagt
     7621 tctgcttcca ggactccccg cgccgcgccc actcgatcgc cgcgcagggc ggcatcaacg
     7681 ccgccaagaa ctaccgcaac gacggcgaca gcgtgtaccg gctgttctac gagacggtca
     7741 agggcggcga cttccggtcc cgcgagtcca acgtgtaccg gctcgccgac atctcccggc
     7801 agatcatcga ccagtgcgtc gcgcagggcg tccccttcgc ccgcgagtac ggcggcctgc
     7861 tcgacaaccg ctccttcggc ggtacgcagg tctcccgcac cttctacgcg cgggggcaga
     7921 cgggccagca gctgctcctc ggcgcctacc aggcgctgat gcggcaggtg gacgccggga
     7981 acgtggagct gtacccgcgg cacgagatgc tcgacctgat catggaggac gggcgggcgc
     8041 gcggcgtcgt cgtccggaac ctgatcaacg gcgaggtcaa gcactacacg gcggacgcgg
     8101 tggtgctggc ctccggcggc tacggcaacg tgtacttcct gtccacgaac gcgatgggct
     8161 cgaacgtcac cgcgtcctgg cgcgcccacc ggcacggcgc cctgttcgcc aacccctgct
     8221 acacccagat ccacccgacg tgcatcccgg tcagcggcga ccaccagtcg aagctgacgc
     8281 tgatgtcgga gtcgctgcgc aacgacggcc gggtgtgggt gccgaagaag gccggcgaca
     8341 cccgcaggcc gtacgacatc cccgaggacg agcgcgacta ctacctggag cgcatctacc
     8401 cgtccttcgg caacctcgtc ccgcgcgaca tcgcctcccg cgccgccaag aacgtctgcg
     8461 acgaggggcg cggcgtcggc cccggcgggc tcggcgtcta cctcgacttc gccgacgcga
     8521 tcgcgcgcct cggccgggac aaggtcgagg ccaagtacgg caacctcttc gagatgtacg
     8581 agcgcatcac cggcgagaac ccctacgaca cgccgatgcg catctacccc gccgtccact
     8641 acacgatggg cggcctgtgg gtggactacg acctggagtc cacgatcccg ggcctgttcg
     8701 tcatcggcga ggcgaacttc tccgaccacg gcgcgaaccg gctgggcgcc tccgcgctga
     8761 tgcagggcct cgcggacggc tacttcgtcc tgccgaacac catcggcgac tacatcgccc
     8821 gcaacagcct ccccccggtc gccgagaccg cggtcagcga ggccgaggag cgggtgcgga
     8881 cgcgcatcga gcggctgctg tcgatcgacg gcgaccgcac cgtcgactcc ttccaccgcg
     8941 agctcggcca catcatgtgg gagtactgcg gcatggagcg caccgaggag gggctgcgca
     9001 aggcgctgga cctcatcccg gcgctgcgcg aggagttctg gacgcgcgtc aaggtcaccg
     9061 gcaggggcga ggagctgaac cagcagctgg agaaggcggg ccgcgtcgcc gacttcttcg
     9121 agctggccga gctgatggtc gtcgacgcgc tgcaccgcgc cgagtcctgc ggcggccact
     9181 tccgggccga gagccaggac gaggacggcg aggccaagcg cgacgacgac aacttcgcct
     9241 acgtcgccgc ctgggaatgg gccggggagg acgcgcagcc cgtcctccac aaggaggccc
     9301 tcaacttcga ctacgtcaag cccacgcaga ggtcgtacaa gtaatgaagc tcacactgcg
     9361 cgtctggcgc cagagcggcc cgcaggacaa gggcgggatg gtcgagtaca agctcgacga
     9421 cgtctccccc gacgcctcgt tcctggagat gctggacgtc ctcaacgaga agctcatcgc
     9481 ctccggcgag gagccggtcg cgttcgacca cgactgccgc gagggcatct gcggcatgtg
     9541 ctcgctggtc atcaacggca ccccgcacgg cccggagcgc gccacgacca cgtgccagct
     9601 ccacatgcgc aagttcaagg acggcgaggt catcgacatc gagccgtggc gggccagggc
     9661 gttcccggtc gtcaaggacc tggtcgtcga ccggtcggcg ttcgaccgga tgatccaggc
     9721 gggcggctac atctccgcgc cgaccggcac cgccccggag gcgcacgcga cgcccgtccc
     9781 gaagcccgac gccgaccgcg cgttcgaggc cgccgagtgc atcggctgcg gcgcctgcgt
     9841 cgcggcctgc ccgaacggct cggccgccct gttcctcggc gccaaggtca cccacctcgg
     9901 cctgatgccg cagggccagc ccgaacgctg ggaccgcgtc gtgtccatgc tggacaccca
     9961 cgaccaggag ggcttcggcg gctgcaccaa caccggcgag tgcaccgtcg cctgcccgaa
    10021 gggcatcccg ctggacgtca tcggccggct gaaccacgac tacctgaagg ccaccgccgg
    10081 cgggaagaag cggtaaccgc cgcccctcgt tctcggtccc gcccggagca ccgggcggga
    10141 ccgttctact gtgtccgcat gaacgtcacg cttctcccct accaccagga cgaacggctc
    10201 cccgacgcgt ccttccccct ttccggtctc gatgtcgtcc ccgtgacgcc ggacctgccc
    10261 gacggcgacg tgtggcagcg cgtcgcggca ctgttcgaac cggtcgtcgc cgaggtcgcc
    10321 cgccagatcg acggcggttc gatgccgcgc gtggtgtcgg gcgactgcct gaccgccgag
    10381 gccgtcctcg cgggcgtgca gaaggccggg gtggacgcct ccgtcgtctg gttcgacgcg
    10441 cacggcgacg tccacacggt ggacagttcg acgtccggct acctcggcgg gatgccgctc
    10501 cggcagatcc tcggcgccga caccgcgctc ctccccgacc ggctgggcct gcgcacgctg
    10561 ccggaggacc gcgccgtcct ggtggacgcc cgcgacctcg acccggccga ggcggagttc
    10621 ctcgcgtcct cgcaggtccg gcgctgcccg gtcgacgacg tggtgctgcc ccccggcccg
    10681 ctgctgctgc acatcgacgt ggacgtcatc gacgccggcg agatgcccgg gctgaagttc
    10741 cccgtcggcg gcgggccgtc ctacgacgcg gtggtcgcgt ccgtccggcg gatcatggcc
    10801 accggccgcg tggccgccct ggacgtcgcc tgcccctggc atccgccgga gggcgacgac
    10861 gacgccgtcc gcacccggct gctgaaggat ctcctgaccg cctgatccga ccgccgaccg
    10921 gtccgctgaa gcgcttcgac aggcgctgat cttgccgtag catgctgctg cacatgcatg
    10981 agggggtgca tatgcatgag ctaatgcact gtgcaggcgg cgccggcccg gcggtgcacc
    11041 ggacgatcct gcgcctggac gtcgagggct acgggcgccg cacgaacggg gaccagctcg
    11101 ccgtgcgggc gggcttatac cgcgccctgc ggcgggccct cgacgagtcc ggcgtgcccg
    11161 cggcctcctg ctactgcgag gaccggggcg acggggccat gatcctcatc cgcccggacg
    11221 tgccgaagga gctgctggcc ggcgcgttcc cggcgcggct ggccgccctg ctggcacggc
    11281 acaacggcgg cgccccgccg gacgcccgca tcagggtccg cgtcgccgtg cacgccggcg
    11341 agatccacca cgacgaccac ggcgtcgccg gcaccgcgat caacaaggcg ttccggctgc
    11401 tggccgccga ccccctcaag gacgcgctgc gcgactcccc cggcgtcctc gccctgatca
    11461 cctccggctg gttcttcgag gaggtcgtgc ggcagaaccc cgcgtgccgc gcggccgcgt
    11521 tccggcccgc gcaggtcgcg gtcaaggagc tccgggagca ggcctggatg cggctgccgg
    11581 actcctggcc gcatgcggac agtgcccgga ccctccggct gctcgccctg caccccggcg
    11641 cggagatctc cgtccctgcc gcggccgtcc tcatcggcgt ccccgacgcc gaggcgcggc
    11701 tcctgctcgg cgacctcggc ctggtggagc gcggcgaggg ccggtacggc gtgcccgccc
    11761 ccgatcccgg ccgcgacccc ggccccgcgc tcgcgccgca ggagcgctcg gccgccgtcc
    11821 gccgcgtcct cgcctggtat ctcggcaccg ccgacaacgc gcgccgcctg ctgtgccccg
    11881 accgcatcac cgccccgccg ctgccggacg agccgggccg cgccctccgc ttcgcctccg
    11941 cggacgaggc ccggcgctgg tgcgagaccg agcggcccaa cctggtcgcc gccgcccgcg
    12001 ccgccgccga cgagggccac cacgacatcg cctggcggct cccgctcgcc ctgtggacgt
    12061 tcttcttcct ccgcggcccc tggaccgacc ggagcgaggc gctccgcaac ggtctcgcgt
    12121 ccgcgcgcct cctcggcgac gaccgcggca tcgcctacgt gctcggcggc ctcggctacg
    12181 ccagccagag ccgatggcgg ttcgaggagt ccgtcgaact gttcaccgcg gcgtgcgagg
    12241 tgttctcccg gctcggggac gtgcggggcg aggcgtggac cctgcacggg ctcggctacg
    12301 cctgccgccg cctccagcgg taccgcgagg ccgtcgccca ccaccgccgg tcggtgctgc
    12361 tggccgccgc ggtgggcgac cgccgcaaca ccggacgcgc gctgacggcc ctcggctacg
    12421 cctacgccgg gctcgccgac ttcggctcgt ccctggacca cttcgagcag gcccacggca
    12481 tcgcactgga ggccgacggg cggaccctcg gctggaccct gcacggcctc ggctacgccc
    12541 accacggcct gcgccgcctg cacaccgcca tcgtccacta cgagaaggcg ctgaacgtct
    12601 tccgcgagtt cggcgaccgt ccgggccagg gcgagaccct ctacaatctc ggccgcgccc
    12661 acatgcagat gtcccgcccc gacgccgccc gcgactgctg gctgctcgcc ctcgccatct
    12721 tcgaggacct ccggaccccg cagaccgaag gcgtcctcgc ccgcctccgc tccctcgatc
    12781 cgagatcatg aggagatgac cctccagcag cacatgcgcc gggccgccga agacgccctg
    12841 cgctcgttcc ccgaggcact cctccccgac atctacgtca tctcgctccg gatctcgcac
    12901 ggcgagttct cgaccgtcca cgaactctgg gactacccct acgacccgta catggcgatc
    12961 ggctacaaca ccgagagcaa cgtccggcag aacctcgaag gctcctccgc ggacccgctg
    13021 gaggtgcgct ggaactacgc ctgcatgctc ctggaggagt ccgggccggc gggacaccac
    13081 cccgccgacc ccgagggcac cgccctctac ctggacgagg tgaagcgcct cggcctctgg
    13141 tacgagccgg acgaagacgc ggaagccgag caggacgagc aggacgaacg gctctgcgcc
    13201 cacttcgacg acctctgcat cgacgccgcg cggcacctgc actccacggg cctcgtccag
    13261 aaggtgctgg gtcgcgaggt gccgatcatc ctcttcgaca tgttccgcgt catcgaaccc
    13321 ggcgccaccc aggcggccaa cccgccccgc ctcgtccccg ccggctacct gaccttccaa
    13381 cagggctgac ggacgccggg ccggggcaat gggcggggaa tcggcatcgg cgaccggcct
    13441 ggcgcctgtc cggaaggtac aagggaagga tggggttact cgcccatcct cacctcctcg
    13501 ttctactggg cgtgccgaat tccaaagccg gagaccgcct gaactgcggc cctggtcagc
    13561 tccgccttgt ttccgaggtt gagcttgccg cgtatgcgct tgacgtaggt gtccaccgtg
    13621 tgacggctga tcccgagatg ccgggcgatc tggccgtgcg tgtatccgtt cgcgatgcag
    13681 tcgaggacct gttgttcgcg aagtgacagc tggtcggtcg ccgccggagt ctccaggaac
    13741 gacgacacct cgttcggaat caccatccgt cccgccgccg ccgttcggac ggcgtccagg
    13801 agggtgttga ccggagcatc agggtgcagg acgccgcggg ctccggcgcg taagcaccgc
    13861 acggcctcct ccctttcctc gggcccgcga gcccagctca gaatgaggac cgaggtcttg
    13921 tgggacaact ccgtgatctg ccgtccgcgc gcgacgccgt cggacggaca gaatcccaga
    13981 aggacgacgt cgagcgtgtt cgacggtacg ccgttcgtgt tcgattgaga aacctcaatt
    14041 gtcacttctt gcgctttatt gaacacatat cgtagtccgt gcaggatgac aggtcgtgga
    14101 tcgatgatgc caagacggat cacttcaccc ccaacgattg cgggcttctg ctcttcgcgc
    14161 gtgccgggcg aacctcatcc gggccacgtc agagaagagt aagtttccgt aagggaactc
    14221 gtgaggaagg tgttttctgc aggggtttca gattgttccg catccaatga tctatgaggt
    14281 gcgccagtta ttcaaggctc ccgagcaata aatgagacga ctcttcctgg ccatcgaata
    14341 actgcaggta gatcaacctc cggcacgaat cacggtccgc tcacgccgat ccgtgccgtc
    14401 tcgatccgct cggtccgcgg attcacagcc gacccgtccg gcggtggacg cccgtcacac
    14461 cgccgaggcg gtcggcccga ccaccggacc gcggagcgcg tgggccggcg cggcaccgtc
    14521 gtccaccgca ttcatcgccg gaccttcgat tcgccatccg gtcatgagaa tcagcgcttc
    14581 gtttccgtct ggtcaccttc gaacacgaag tgtggcaggc gctctctcgg cccgtcaggg
    14641 aacagggccg gccaattcac gtccacaccc tccacccaca ggcggcccaa cgccgtcagc
    14701 acgccggcca cgtccgaatc gcgggccgcc gttgtgggaa gggtgctcag aatcgtgccg
    14761 tccggtcgtc ggccgggatg ttgctggacc agcgtgccga gcgttcggcc cgcaccgacc
    14821 tccaccagta tcggtgccgg cagacgccag agctcggcca gttcgtcctc gaagcggacg
    14881 gtccgggaca tgtgctgtgc ccagtattcg gggctggtcg cctggacctc ggtcagccac
    14941 gttccggtga cattcgacag cagcgggatg gtgggcggac gcagcgggaa cccggcggcc
    15001 agttcacgca tcccctcctc gaacggctcg agcatcgccg tgtggaaggc gtgccgggtg
    15061 ggcagccgca ggctggccac gccctcggcc gcgagccgcc tttcaaggcg ttccaccgcc
    15121 gtgatccggc cgccgaccac cgagagccgc ggaccatcgg ccgccgacag cgacagctca
    15181 ccgtcgaggt ggtcggcgag gtggtcggcg ccgagcatca ccgcgaccat cgcaccctcg
    15241 ggtgcggtct cgatcagctt cgcccggcgc gccaccagtt ccagcgcgtc ctccggtgcc
    15301 agcacctccg ccgcacacgc ggcgacgtat tcccccaggc tgtagccggc caatgccgtg
    15361 ggacggattc ccgcacccat caggaacctg gccagcgcgt actcgacggc gaagaccagg
    15421 ggctgggccg tcgcggtccg gtccagctcg ccggaccgtt cgtcccggcc gagcagccgg
    15481 gccaggtcga gtctgccgtg cggcccgtcc gccggcggcg cggcctcgcc gttctccgga
    15541 tagaggattt cacgcagatc ccggccgagc tggtttatga ggacctcggc gcagtggtcg
    15601 agcgcgctac ggaaaagggg ttcgctccgg taaaggccgg ccgccatccc ggcatagtgg
    15661 tcaccgaccc cggggaaaag aaaggcgagg ggacgctcgg ccgtcgtcgc gtgtccgatg
    15721 tgcgtctcgc gggcggccgg ggcctggagc cgccgcgccg cgtcggcgca gtcgcgcgcc
    15781 accagtgcca ggcggtgcgg tagccgcggc cggtcatgga ccagggatcc cgccaccgcg
    15841 gcgagcggaa ggctcggcct gccggccagg aaccgagcca gcccgcgtgc ggccgcggca
    15901 agttcgtcac tggatgaggc tgacaggacg acgagctcgt agggcctggt cacactgttc
    15961 ctctcggtgc ggggccccgg ggacggcccc tcagggcggt ccccgggcct acggtggtct
    16021 gagcgggatc aagaagagcc ggggaccgcc tgggaatcca tctgcctgcg caggctcagt
    16081 ggccgcatgt ccgtccacac ctggtcgatg tgggccaggc actcaggctt ggttccccgg
    16141 gtgccctccg cgcgccaccc cgccgggatc tcccggtcct ccggccagat cgagtactgc
    16201 tcctcgtggt tggtcacgac ccggtaggtc cgctcgtcgt cgtcatcgaa catttccctc
    16261 tcctctcgcg ttctccagaa attccatgcc gttcagtcgt gctccacccg gccggcatgc
    16321 gcatcccccg gaagggattc gtcggcgtcc cacaggtggt gcatttccgt gcaggtctcc
    16381 agcagttcgt ccaaggtgcc gacggcggac atctcaccgt cgacgagcac cacgatctga
    16441 tcggcccggc ggaggatgga cggccggtgc gaaacggcca ggatcgtggc gccgccgtgg
    16501 tccagaagcc ggtcccacaa ccggcgctcg gtggtgacgt ccagcgcgtt ggacaggtcg
    16561 tcgaagacca tcaggtcggt acggcgcacg gccatccggg cggcggcgat ccgctgcctc
    16621 tggcccccgg acaggcgcag acctcgcggc ccgatcacgg tgtcgaggcc cttgtccaga
    16681 ccggcgatgt cgtcttcgag cacggcgagg cgcaccgcct cggccacctc cgtcggcgag
    16741 gagggggcac cgagcgtgat gttctcccgg atcgtgccgc tgaacagccg ggggacctgc
    16801 ggcacgaaac tcgaccgcgg cggggtcagg aacgtctcgg gatggtcgac gggcacgccg
    16861 ttccagagga ccgtgccgcg ctcggcgggg agcagcccga ggagcacttg caggagggtg
    16921 ctcttgccgg atccgaccct gccggtcacg accgtgaccg tgccggcggg caggtggaga
    16981 tcgatgtcgc ggacgccgcg tgaggtcccc gggtagcgcg aggtgaggcc acgggcctcc
    17041 agcaggcgca gcggcgcgga acggtcttcg cggggtgccg gccgcggcgg ctcgcgccgc
    17101 aggtgggtcc gcgtgcgggc gatcaccgct gattcgtcgt cggcgagttc ggccacccgg
    17161 cgcgtggaga gttcggcctt ctggaaccgg gcgaagaaca tgcccagcgc ggtcaccgcc
    17221 tcggtgatga actggatgta gaagacgaag agcgccaggt cgcccacggt gaactcgccg
    17281 ccgcgcatgc gcgccgcggc cagcagcagc acgaacccgg tgccgagcgc ggccgtgccg
    17341 ttgaacaggg acgtctgcac ggtggtcagg agcacctcgc gggcggcgag acgcagcctg
    17401 acggcgttgg cctgccgcag ccgcgcgacg aaccgttcct cggcacgtcc gaccttgatc
    17461 gcctgaaccc cgccgaccgc ctccccgacg acgctgctca cctccgcggc cgcccggcga
    17521 ccggcgttct ggcattcgcg cagcggcctt gccagcgccc ggctcgccag caccatgacc
    17581 accaccggga cgacgagccc caaggtcacg acggcgtcga taccgagcat gatgatcaac
    17641 gccgccacgg cgatgatcaa ccgggagagg ttggacgccg accagatcgc gaagacgccg
    17701 acctcgtcgg tgtcggcgcc gaaccggctg acggcgtcgc cgccggtgcg gtccagcgct
    17761 cgcccggcgg gtttgcgcag gatcgcgcgc agcgcgttga cctgcagggc cgcgcggatc
    17821 cggtaggtga agtgcggttc gacccggctg aggatcacgc cgtaccacac ggtcaccttg
    17881 gtggcctccg cggccgccac cagggcgatg agcgaccagg ccgacgtgcc ggccggatcg
    17941 gtgccgctga gggtgtcgaa gaccatctgg agcaacagtc cggtggccag gagcgcgccc
    18001 cgcagcagga tccacagtcc ggtcaggccg aggtaggtgg gcgccgaacg ggacaacagc
    18061 gggatcagca gcgcccgccg gacggaacgt ccccgggggg gcgcgggcgg cggctccgac
    18121 cggcgtgtcc gcggtgccct catgccagtg cctcgttggc ggcgagcagg cgggagaacc
    18181 gcgaggacgg atccgcgacc agccggtccc gtgggccgtg ctcggcgacg cggccatcgc
    18241 tgagcaggag cacctcgtcg acggtgccga gggtttcgag ccggtgcgcc acgatgatcg
    18301 cggtgcgtcc ggcgagcagg cgttccatgg ccgtctcgaa gacccgcagg ctcgccgggt
    18361 ccagtcgcga cgtggcctcg tccaggagca ccaggccggg gtcctggatc aggacgcggg
    18421 cgaaggccag caactgctcc tggccggccg acagcccggt gtcgcccggg ccgaggaggg
    18481 tgtccagccc cgcgggcagg ctctccagcc actgccgcag ccccacctcc gcgagcgcct
    18541 cgcgcacccg ggcgtcgtcg accgtgtcat cgaagagcgt gacgttgtcg cggaccgtgg
    18601 cggcgaacaa ctggacctcc tgcgtgacca ggccgacctg gtcgcgcagt gaggccaccg
    18661 agatctcccg cacgtcgcgg ccgtcgaacc ggaccgtccc ctgggtgggg tcggcgaatc
    18721 ggaacaacag gcgtatcagg gtgctctttc cgctgcctgt acggccgact atggccagcc
    18781 gggtcttcgg ccggaggcgc agggagatat cgcggagcgc atcttcttcg ggcctgtagc
    18841 tgaacgagac gcgctcgaat tccacggcgg gcgcccccgc gggcagggtg gcttcgccgg
    18901 tgcggaccac gctgtgctcg tcgagcaggc cgtggatgcg ccgcagcgcc cccagggcgg
    18961 cttcgagatc atgaaactgc gaggtgatca ccagcatggg ggtctgcacc atgaccgcgt
    19021 agacgaccag ggtgtaggcg gcgccgaggg tgatctggcc ggacgtgtag agccatacgc
    19081 cggccccgag ggccatgacg aaccccgccg acgccagtga ctgcgcggcc gcgggccagc
    19141 gcacccccag cagcgcggcg cggcgactgg cccagaacag cgttccggcg taggtccaga
    19201 agccgtgcac ggtgtgttct tcggctccgt tggcccgcag atcgggaagt ccgttcaggc
    19261 gttcctcgaa gaacccgagc agtttcgcgt tggcctcccg ctgggccgcc atcgccggca
    19321 cggcggtgcc gaccagtctc cgcagcaaga agaaggaggc ggtgacgaac ggcgcgtaca
    19381 ccagtccgat ccgccagtcc tggacgaaca gcgcgacccc gatcccgacc accagcagca
    19441 cgttggacag gaccagcagg aacatctgcg agaaatagtt ggccagcttg ctcacgtctc
    19501 cgtcgatccg gtcgatcaac tctccggggg cgtgccgctc atagaaggac atgtccagcc
    19561 ggaggcagtg ctcggtcaga tcggcgcgca actcgttcgt cgcgctccag gccacccggg
    19621 cgccccggta ttcggcgacg atccagatca cctgcgccac caccgcgacc gacaggtaga
    19681 tcgcgccgag ccccagcaga ttcgacagcg gggcaccgga gcggacaccg tcgatgaacc
    19741 tccccagcaa ctgcgggttg gccacctgga gcgccgtgta gaccagtgtc gtcaccgcga
    19801 gcacggcggc tacggcccgg tgcggcccca ggtaggtgcg aagggttctt gcggcgttcg
    19861 atcccacggt gccgtccgcg ttcccggtac tcgaaggctc ggcactcgca tgcgccatac
    19921 aacggttcct tcagacgatg gattctttga gcattcgggg cggtcacccc atggccatga
    19981 tgtcggtcaa cgctcctcgg tcagcggtct tcggtcaacg cggtcaacag cgtgtccagc
    20041 cggtcctggt cgagtcccga ctcggggaaa tcggagggcg tgtagccccc ggcctccggc
    20101 cgggtgcagt gcgagatcag ttcgcggagg ccggcgatgg tctcctcggc gaggcgctcg
    20161 accgcctggt cgctgtagtg cgccgtgctg taggagaagg tgatgtccag gtgcccgtcg
    20221 atggtgatcg catcgatgtc gagcaggtgc gggcgcgcgt tctccgggtg gaacgcgggc
    20281 ggcggcgatt caggcgcccg ccgcagccgc agcgccggtc cgtcatgggc gcctggttcc
    20341 gtgtggtcac cggcgatggc ggtgtcgaac tggcccaggt agttgaagcc gacgcgtggc
    20401 gccggccgtg ccgcgagggt cgatgcgtgc gccgaatgca gatagcgcag cagaccgtag
    20461 ctcaacccgt gatgcggcac cgcgcgcaac tgctctttga ccgccttgag agccgttccg
    20521 ggatcgtcgc ccgggggcag gctgagcgtc accggggcga tggaggtgaa ccagcccagg
    20581 gtgcgggaca ggtctgctcc gtcgaccaga tgctgttccc tgccgtggcc ctcaagccac
    20641 agcgacacgt gattcgacgc cgtcgaccgg gtcagcgccc gcgtcagcgc ggtgagcagc
    20701 acgtcgtcga tatgggttcg gtaggcccgc ggaacttcgc gcagcagcag ccgggtctgc
    20761 tccacgtcca ggccgaccgt ggtgcgcgcc gtgtcctcct cgcgggcgtg ctccggtggc
    20821 tgcggcaggt caggctccgg accggcaggg tccgccgacg tctgggagag ccagaagtcc
    20881 aggtcggcct ctgtctcggg ggcgtgcgcc agctcgcgca gggcccgcgc ccaggcggag
    20941 atcggcgtgg tcgcggacgg caggcgaacc ggcgccccgg tggcggcctg ccggaatgcc
    21001 gtgtggagat cctccaggag gacgcgccag gacactccgt cgatgaccag gtgatgggcc
    21061 agcagagcca gccggcgccg gtccggccgg ccgccgtcga tcaccagcac ccgcagcagg
    21121 ggcggtctgc ccaggtcgaa ctcggcggcc gccgcaagcg ccgcgcccag cgccgcgtcc
    21181 cagtcgtcgc tctcggccac gtcgaccagg gtgaccgact cgtcggtcgc ggcgcggtcc
    21241 acggcccgcg cctcggcgtg ccatcggccg tgcgggccgc tccggtcgaa gcgcaggcga
    21301 agggcctcgt gccggtcgcc gagggcggcg accacgtccc ggaggtgccc ggcgatccgg
    21361 gcgcagtcgg cgtcggcgtc cagcgcgaac agccatccct ggttccagtg ccccggacgg
    21421 gtgagcccct gctcgaagaa ccagtgctgg acgggcgtga ggggcaggtc gcgggcgtcg
    21481 gcggccgatc ccttccgggc gtgccgcacg ccgatggggc gggtcatggg ctcggccacg
    21541 gcggcgagtt cgcggacggt ctgcttgtcg aagaactgcc gcggcgtgat ccgcagcccc
    21601 tcctgagcgg cccgggagac caccatgatg ctgaggatcg agtcgccgcc gagttcgaag
    21661 aagttgtcca gcgcgccgac ccggtccacg ccgagcacgt cggcccatat cgcgccgagg
    21721 gtcttctcgg cggggtcgcg cggcgggacg aactcctgcg ccagctcggg acggactccg
    21781 tcgggagccg gcagcatcgc ccggtccacc ttgccgttcg cggtcagggg aagggcgtcc
    21841 agccagacga acacggccgg gaccatgtag tcgggcagcc gcgcggcgag gtggtcgcgc
    21901 agctccgaga ccggcaccgg ttcggcgccc cgcgccggca gcacgtaggc caccagccgc
    21961 cgtgaggagg tgtcctcctg gtcctgggtc gtcaccacca cgtcgcggac cgcgggatgg
    22021 ccggagagca ccgcctcgat ctcccccagc tcgatgcgga acccgcggac cttgacctgg
    22081 tggtcggccc ggccgacgaa ctccaggcat ccgtcgggca tccagcggac gaggtctcct
    22141 gtccggtaca gccggccgcc gccggtgccg aacgggtccg gcacgaaccg ttcggcggtc
    22201 attccgggcc gcgccagata gccccgggcc actcccgagc cgccgacgta cagttcgccc
    22261 gggacgcccg cgggcaccgg gcgcagctct ggatcgagca cgtagccccg tgttccggtg
    22321 agcggccggc cgatgggcac ccgggtgacg tcggaccggt ccggcacggg ccagatcacg
    22381 cacgacaccg atgtctcggt ggggccgtag acgttggcgg cctcggcgtg gcagacctcg
    22441 cggaaggcgt tgaccaggcc ggccggcagg gcctcaccgg cgatcaggac gagcctcaga
    22501 tggtggccga ggcggcgccg agggtcggcg agcacggtgt tgagcagcga cggcacgtag
    22561 gacacgacgg tcaccttgtg ctcgtccatc acctgggcca ggcgctcggg gtccttggcg
    22621 tcggtgtccg gcaccaccag agcggcgccg gtcaggaacg gccagaagac ctcccagacc
    22681 gacgcgtcga atccgaccga ggtgcgctgc gcgatccggt cgccgggccc gatcgggaac
    22741 gtgcgctgca tccagcccag atggttgagg accccccggt gggtggtcat gacccccttc
    22801 gggcggccgg tcgagcccga ggtgcagatg atgtacagca ggttgtccga ggacacaccc
    22861 ggctctggcg gggtggccgg tgcgcggccg atctcttccg cctcggcctc cagcctcatc
    22921 acccgcgccg cgccggctcg cggcaaccgg tcggcggcgg taccccctgt caggacgagc
    22981 cgcacaccgg tgtcggcgat cagggaggcg atgcgggcct ccgggtactc cggatccagg
    23041 ggcacgtagc agccgcccgc cttcaccacg gccagcagcg ccaccagcag ttcgaccgag
    23101 cgttccagac acacggcgac cggcacgtcg gggcccacgc ccgcggcgcg gagatggtgc
    23161 gccagccggt tgatgcgcac gtcgaattgg cggtaggtca ggcgctgctc tccgcagatc
    23221 accgcgagcg cgtcggggcg ccggcgggcc tgttcgtcga ggagttcggg gacggtgggg
    23281 ccgagaaggt cgggctcgcc tccatcggcc cagtcgcgca gcagccggtc tccttcggcg
    23341 gaggtgaggt gccgcagtcc cccgaccggg cggtcctggt cgtcggcgag gccgtccgcg
    23401 atgccggtga ggagcgtgcg gaggtgtccg agcagccgct ccgccgccgg atcggacagg
    23461 cgccgccggt catggtgaag gcgcacctcc agatcatcgg tccccgccac gacgagcgtc
    23521 acggggtagt ggggccgttc gtgagctcgg acgccggtga cgcggaggtc ctcgtcggcg
    23581 ccgagccatc cggtgcgcac cgggtagttc tcataggcga cgatgctgtc gaacagtgcg
    23641 gtcccaccgg ggacatcgct ccagcgctgc acctgggcga ggggactgta gtcgtatcgc
    23701 cggccggcgg ccaggtcctt ctgcagagtg gccagccact gcaggagcgg tgcggactcg
    23761 tcgacgcgga cccggatcgg cagggtggcg ctgagcaggc ccaccatccg ctcgacgtcc
    23821 ggcacctgcg gcgggcgggt ggacacgacc gagccgaaca ccacgtcgcg ctgcccgctg
    23881 taccggctga gcagcagcgc ccacgccccg tggacgaccg tgcccagggt gaggtgccgg
    23941 cgcttggcca ggtcctccag ccgggcccgc aactcgtccg gcaggacatc ggtgatctcg
    24001 ccgaagccgg gctcgccccg cgccgccgga tggccgacgg acagcggcgt gggttcgcgg
    24061 aacccggcca gatgctcccg ccagtgccgc tccgccgcgg cagggtcctg cccgtgcagc
    24121 catgccacgt actcccagtg cggcgggccc ggtgcggcct cctccgtgcc gtcggcgtcc
    24181 gcccgccggt accgggtgaa cgcgtcgtcg acgaccagct ggaccgacca gccgtcgagc
    24241 agcagatggt ggaacgtcag gacgagccac cagtcctcgt ccgtgagccg caccagcacc
    24301 atgcgcacca gcggggcgcg ggcgagttcg aacgggcggg agcggtcgtc ctccagcagc
    24361 ccgctcagct cctgctcccg ctcctcgtgg gacaccgcgc gccagtccag ctccgtccag
    24421 ggcaccggga cggaggtccg tacgacctgg aggggctcat cggtgccctc ccagacgaag
    24481 gccgtgcgga gggccggatg ccggtcggcc acccactgcc aggagtcgcg caggcgcgac
    24541 gcgtccagcg gaccgcgcag cgtgaacacg atctggttga cgtagaaccc ggcggccgga
    24601 tcacccacgc tgtgcagcag cattccctgc tgcatcgccg tgagcgggaa gaccttttcc
    24661 acttcaccgt tgtcgatcat catgatcctt cgctgagccg gtcctgctcg cgcatgacgg
    24721 agaggatgta gtcgaacgtg tccccatcga tccgggtgac ggggaaccgg tcgtcgccgg
    24781 aggcgtcggg gacgccggga cggtccggtc cggaccatcg ggcgagccgg gccagatccg
    24841 cgatggtctg cttgtcgaag aactgctccg gcgtgatgtg cagcccctcc cgggcgaccc
    24901 gggagacgac catgatgctg aggatcgagt cgccgcccag ctcgaagaag ttgtcgaaca
    24961 cgccgacccg gtccaccgcc agcacacggg tccaggcatc ggccaggatc ttctcagcgc
    25021 ggtcacgagg cggcacgaag cgcccgcccg tctgctccct ggtgacctcg gccgccggca
    25081 gtgccgcacg atccaccttc ccgctggcgg tgagcggcag ggacgccagc cactggaagg
    25141 ccgacgggac catgtactcc ggcagccggg cggccaggaa ctcccgcagg cgggggacgg
    25201 ggacctccga gccgtcgccc gccggcacca ggtgcgccac gaggcgcgtc gtatcggcgc
    25261 cgtcccgccg ggtcgtgacc accacgtcgc ggacggcggg gtgttcggcc agcacggcct
    25321 cgatctcgcc gagctcgatg cgcagtcccc gcaccttgac ctggaagtcg gtgcggccga
    25381 ggaactccag ttctccgtcc ggcagccggc ggaccctgtc cccggtgcgg tagaggcgcc
    25441 cgccgtcgcc ggtgaagggg tcgggggcga accgttcggc ggtggtcccc ggccggttca
    25501 gatagccgcg gccgacctgg acgccgccca ggcacagctc ccccggcacg cccaccggga
    25561 cccgctgccc ttcgccgtcg agcacctcgg ctcgcgtgtt gctcaccggc cggccgatcg
    25621 ggacggtccg ctcggccgga tcgcagggat gccaggtgac gtcgatcgtc gcctcggtcg
    25681 gcccgtacag gttgtgcagg gcgacgccgg gcaggacctc ggcgaagcgt cgcgcgagct
    25741 ccgccggcag gggttccccg gaacagatca cccgccgcag gcaggccggg cggccgagtt
    25801 cccgcacccg atccaggaac gggttgagca tgctcggcac gaagtgcacg gtctgcacgt
    25861 ccgcacgcgt gacgagttcg aggagatggt ccgggtcgcg gtgccggccc ggctcggcga
    25921 cgatcagccc ggccccggcg gtgagcggcc agaacagctc ccacaccgac acgtcgaacg
    25981 tgaacggcgt cttgtgcagg acgcggtcct gcggtccgag cgggaaggcc tcctgcatcc
    26041 agcgcagccg gttcaccagg ctccggtggc tgatgccgac gcctttcggg cggcccgtcg
    26101 agccggacgt gtagatgacg taggcgagtt cgtccccggc ctcggcgccg tcgcccgtga
    26161 acgccggtgc gcctgcctcc acgggcgtgt cgaggtcccc gtcgtcccag cgcagcagcg
    26221 tcgccccggc gccggtcagg tcgtccgcat ggtcgtcgga ggtcaggacg acggtggcgc
    26281 ccgagtcctc gacggcgaat cgtcggcggg aggccgggtg atcgggatcc agggggaggt
    26341 acgcgccgcc cgccgcgagc acggcgtgca ccgcgaccac cagctccacg ccgcggtgca
    26401 ggcatacccc gaccacgcgc tccgggccga cgccggcgcg gcgcagccgt cccgccagcc
    26461 gatcgaccgc ggcggcgaac tcgcgatagg tgatccgtcg ctcgccgaac ccgagcgcga
    26521 gcgcgtgcgg cgaagccgcc gcctgctcgg ccaccaggtg cggcaggcgc acgcgccgat
    26581 gagcgcggcg ggtgcggttc cattccgcga tctggtcgtg ttccccggcg gtgagcatgg
    26641 ggagcgtcgc caccgggcgg tccggctcgg ccaccgcggc ggccagcagc gtcagcaggt
    26701 ggccggtgag ccgttcgacg gtgtccgccg tgaacaggtc cacgtcgtac tcgaatacgc
    26761 cgcgcaaccg gtcggtgtcc tcgaccaggt agagcgccag gtcgaacttc gccgtaccgg
    26821 tgtccggagg gaagagctcc tcggcctgcc cggcggttcc gtccagcggc gccgcggcct
    26881 gcagggtcag catcacctgg aagagggggt tgtgcgccat gctccgccgc ggcgccaact
    26941 cctccacgag ccgttcgaaa ggcatctcct ggtgggcgta ggcgcgcagg caggtgcggc
    27001 ggaccccgtc cagcaaccgg cggaacgacg gccgtccgga ggtgtcggtg cgcagcacca
    27061 gggtgttggc gaagaacccc gccagctcct cgacatcggc ggccggccgg ccggcgaccg
    27121 gggcgccgac cacgacgtcc gactggccgg accagcggga caggacggcg gcgaagccgg
    27181 cgagcagcgt catgaacagc gtcgcgccct cggcggcgcc cagtctccgc atcgcggcga
    27241 gcagggccgg aggcacctcc acgtcgtggc gggctccgcg gtgcgcctga acacgcgggc
    27301 gcgggcgatc ggtcggtagt tccaggagct gcggcgcccc ggcgagttcg tccgtccaga
    27361 accgcaccag ttccgcctgc cgctcgctgg tcagcagctc gcgctgccag gcggcgaagt
    27421 cggcgaactg caccggcagc ggcgccaggg tgtcggaggc gaggagacgg agcagatcgc
    27481 gcaacagcac accgcccgac cagccgtcgg tgatgaggtg gtgcagggtg agacccagta
    27541 cgtggtctcc ttcggacagc cggatcaggc aggcccgcca cagcggtgcc gtgcccaggt
    27601 cgaagagacg ccgcgcctcg gcgtccagca ggtcgcgggc cccggcgagc ggatccgccg
    27661 accccccgct cggggccggc gggccggatc cgtcgagctc gatctccttg agctcgacgt
    27721 cgacggactc gtgcaccgtc tggaacggac gtccgtccac caccgtcacc gaggtgcgca
    27781 gaacctcgtg gcgcccggcc aactcggcca gcgcgacgcg cagccgggcg gtgtccagct
    27841 cacagcgcag ccgcacggcc acggggacgt tgtacgtggc ctgaccgggt tgcagttgct
    27901 ccagcaccca gagacgttcc tgggagaacg acgccggaag gggcccgccg tcgcgtggct
    27961 cccggcgcag ctccggggtc gcgacggtgg cctcgtgccg tccgagcgcc tcccgaacgg
    28021 cgctcgcggc gccggcgacg gtcgcctcct cgaacagttc ggcgattccc aggtcgacgc
    28081 cgaagacgtc ctgcacccgg gtcagcagcc gtaccgcgag gatcgagttg ccgctcagcg
    28141 cgaagaagtt gtcgaacacc ccgaagcgat cggtccgtag tacctcggcc cagagtccgg
    28201 ccagcgtgcg ctcgatgtcg tcgcgaggcg ggacggagtc ctccggcggc tgcccgtcca
    28261 ccgtctcggg gatcggcagc gcctgccggt cgatcttccc gttggccgtc accggaagcg
    28321 cctccagcag cacgaacgcc gccgggacca tgtagtcggg caaccgggat gccgcgaacc
    28381 cccgcagttc ctccggacga ggccgctccg cctccgcggg caccagatag cccaccagcc
    28441 gccgcgagtc ggggccgtgg tcctcccgga ccgtcacgac cgcttcgcgg accccgggat
    28501 ggcgggtcag cgcggcctcg atctcgccgg gttcgacgcg gaacccgcgt atcttcacct
    28561 ggaagtcggc tctgccgacg aagtccaggg tgccgttccg cgcccaccgc acgagatcac
    28621 ccgtccggta cagccggccg cctccgcgct ggaacgggtc cggcacgaac cgctccgcgg
    28681 tcagccccgg gcgccccgcg tacccccggc cgatcccggt gccgccgagg tagagctcgc
    28741 cgacgactcc ggcgggcacc ggctgcatct cgcggtcgac cacgtaggcc cgcatccccg
    28801 gcaccggcct gccgatggtc gcgatcgggc cggacgtgcc gtccggcggc gcgtcgatca
    28861 cggcgtggca ctggtcgtcg ctgcactcgg tgaggccgta ggtgttgagc agcgggacgg
    28921 cgggatggag gtcgagccac cggcgcacga gatcgccggg cagcgcgtcg cccgtgggca
    28981 ccagccagcg cagtcccgcc agccgcgacg cggcgggacc ggcgagcatc atgctgatcg
    29041 ccgcgggcac ggcctggagc acgctcaccc cgccgctccg cacctcttcg gcgagccgtt
    29101 cgggatcctc cagggcctca tcgggcacca cgtgcacccg gccgccgatc gtcagcgggg
    29161 tgaggcactg ccacaccacc acgtcgaagg tggccggccc gttctgggcg agcacgtccg
    29221 ccggtcccat gcccagatcg ctgatcttgg cggtcatgtg gttgagcagg ccgcggtgca
    29281 ggacgccggc ccccttcggc gcgccggtgg tgccggaggt gaacatgacg taggccaccg
    29341 cgtcggggag gcagcgggcc ggcggatccc cggcgggccg gtcgagatgg gcccgcgggt
    29401 cgatgtcgat ccagacgggg cgccggtcct gcggcgccgc cgccatcgcg ccggtgaggg
    29461 cctcgcggcc cgccgcgtcg cccagcacca cgccgcagcc gctctgggcg atgatgtagc
    29521 gcagccggtc ggcaggctgg gccgggctga gcgggacgaa cgcgccccct gccttgagcg
    29581 tggcgagcat ccccgcgatg aagtcgggac cccgccgggc catgagaccg acgaacatct
    29641 cggccccggg ccccggcccg agcgaccggt gttcgcgcag ccggtgcgcc agccggttgg
    29701 cgcgcgcgtt gagttccgcg tagctgaccc gttcggagcc gctgctgacg gcgatggcct
    29761 ccggggtgcg ggccgcctgc gcttcgaaca acgccggcag gcagtcttcc ggccggtcca
    29821 cggtcaccgg ggccggccca ccgtcggccc agccggccag cgtccggcgt tcggacgccg
    29881 tcagcagcgg cagggcggcc accggccggt cggggtcggc cgcggccgcg gccagcaacg
    29941 tgcgcaggct gccggccagc cgctgcgccg tatccctgtc gaagaggccc gtgtcgtagt
    30001 ccaacgcgcc gctgagagcg ttctcgcgct ccgtgaatcg cacagccagg tccagggacg
    30061 tcccggcagg acccctggcc ggcgccaccg gggcgtccag cacttcgtcg tccagcgtga
    30121 gcgccacctg gaacacgggg tggtgggccg ggtccggcgg cagcgccaac gcctccacca
    30181 gggactcgaa ggggagatca ctgtgcgcgt ccacccgttc gcacgtccgc cgcagccgcc
    30241 ccaccacctc gcggaacgac gggcggcccg agaggtccgc gcgcgtcggc atcggcgaac
    30301 ccaccacgat gtccgtgaga ccggaccatc gcgccacgac gacggagaag gccgccagca
    30361 gcgggacgag aggcgtcgtc cgctcagcgg cggccagttc cctcaaggag gaaagggtct
    30421 ccccgggcac ctcgacgggg agccgcccgg ttcgacggga cgccgcatga cggggtcgat
    30481 cggtcggaag cgtcaggacc tcgggcgcgc cggaaagctc ctcccgccag aacgcgacga
    30541 gtgggaccat ctcgacctcc ttgctgcgtt ggaccggcgg gcggccgggc ggtcgaccgg
    30601 gcgccggcct cacgagcggc tcagcggtcg ccgcgggggt gacgacgacc agtcgaatct
    30661 cggttcggcc ggggcgtccg cgtagagcag gtcgagatag cgctcaccgc ggtccggtag
    30721 aagggtcagc acccgcaccg ggcgaggcag ccgcggcagg agctgccaga gcccggcgac
    30781 gacggccccg gacgaccctc cggcgaggat cccttcggag cgcagcagtt cgtggcagcc
    30841 ttggacggcc tggtcgtcgt cgacgaggac cacgtcgtcg atctcgtccc ggcacaggag
    30901 ctcggggaca cggcccgcac cgatgccggg cacccggcgc ggggccggcg gatgaccgaa
    30961 gatcaccgag ccgacggcgt ccacggcgac gacccgcaac cgcggatacg cgacgcgcag
    31021 cgcccgggcg accccgtgga tggtccccgt ggtgctcacc gccatgacca cgcagtccag
    31081 cggcccgtcg acgtcggcga ggatctcctt cccggtggtc tccgcgtgcg cctgccagtt
    31141 cagccggttc gcgtactggt tgacccacac ggacccgggc acggcgccga cgatctcccg
    31201 gacccggcgc aggcgctgct ccaggtagcc gccgctgccg tcgccctcgc tcaccatgtc
    31261 gacgttcgcg ccgtaccggc gcagcagctg caggttcgtg gcggtgatgt tcgggtcgac
    31321 gaccaccgtc aacgccaggt cgtagatccg gcacaccatg gccagcgcga tcccgaagtt
    31381 gcccgaggtg ctctcgacca ggtgcgagtc gggggcgatg gcgccgttcc gcaggccctc
    31441 ctcgatgatg tgccgagccg ggcggtcctt gacgctgccg ccggggttga gcatctccag
    31501 cttggcgagg acctcgacgc ccgggtcgtc gaacagccgg cgcagcgcga cgatcggcgt
    31561 gcggccgatg cagctgacca cggattcgtg gatcaccggt ccgctcccgg gtccccgtgc
    31621 gcgggctcgt ccaggcatgc ctccagccgc cgggccacct cggcgacggc cggtccgtag
    31681 acgaactcca tatgggagcc ggcgtcgatc tcctcgacct tcaggccgcc gatcgggaag
    31741 cgggcccact cggccggcag gtcgcggtcg gtgcggtccc gctgcgtcag cagcgtcacc
    31801 gttcccggat aggacggacg gtagggggag atggcccgcg cgttcagctc cagacggcgg
    31861 cagaacgact cgaactcggc cggctcgacg tccggcggca ggtcaccggc gcgctttccg
    31921 gcctccagga cccgctgcaa ctgcgcccgc gggtccagcc cgcgcagttc atcctccggc
    31981 ggtgagaaca gcagccaccc cgcgaggatg aacgcgcggt caggtgcggg tggagcgtcg
    32041 gtgagcggtg ccgtgtccag cagcgccacc gtgcccaccc ggtcgcctgc ggcgtgcagg
    32101 cggtcggcga ccgccagcgc gaacctgccc gctcccgaga agccgcacag gtggtacggc
    32161 ccctccgggt ggacccggcg cacttcttcg gcgtagcggt ccgccatctg ctccatggtc
    32221 agcacgcccg ggtcggctcc gccgtggaag aagccgtcgt tctggacgcc gtagagcgcc
    32281 cggccggtgc ccagcgccct ggccagctcg aaatagtggt acagctctcc gagcaccgcg
    32341 tgcaggaaga acagcggggc tcgcggccca ccgggctgca actccacgac gaactgggga
    32401 tccggcgaga tcgtctcgcc ggagcggatc cagtcggcca gcgcctccac cgtgcgcgtc
    32461 gcgtacaggt cgtgcagggt caccgaccgg cccgtgagcc tgcacagccg gtcgaccacc
    32521 agcatccccg gcatggaact gccgccgagt tcgaagaact cgtcgtgcgc gccgatcggc
    32581 gtgacgccga gcacctccga ccagacctgc gcgacgtaac gctcccagcg gtcgcgcggc
    32641 tcgacgaagc cgggggaggc cggccagagg gacggggcgg gcggctcacc ggggtcgccg
    32701 gtctccggag tactccccga cggggttccc ggccgctgtc ccggtcgcgg gtccggcagg
    32761 tgggcgatgg gcaggtcggg atcggcggtg acggcggcaa ggacctcgac caggtatccc
    32821 gcgaggcgct cgatggtcgc cgcgtcgaag atgtcggtgg cgtactcgaa cgttccggcc
    32881 agccggcccc ggtcctcgtt caggtagagc gacaggtcga acttcgctcc ggcgccgctg
    32941 gggacggcca ccggctccgc gaccgtcccc ggaaggtcga ggtggccgcg cggtacgttg
    33001 ccgaacccga aattgacctg gaagaggggg ttgtaggcgg tgtcgcgcgt cggcgccagg
    33061 tgttcgacga gtttctcgaa gggcaggtcc tggtgctcga acgcgcgcag ggactgccgg
    33121 cgcacgtggt ggaggagccg ccggaacgag gggccgccgg acaggtccgt gcggaccacc
    33181 acgctgttga cgaagaagcc gatcaggccc tcgaggtccg ggtggtggcg ccccgcgacg
    33241 ggtgttccca cgacgacgtc ggtctctccc gaccatcgcg acagcacggt gacgaacgcg
    33301 gccagcaatg ccatgaacag cgtgacgtcg gtgctgccgc tcagttcccg ggccgcccgg
    33361 agcaggtcgc cgggcacctc gaagtcatgg cgggcgccgc ggccgctccg cacctgaggt
    33421 ctcggccggt cggtgggcag ggccagcagt tccggggcgc cggcgagctc ctccttccag
    33481 aagcccgtca atccggcgac caggtcgtcg gtcaggcgct cgcgctgcca gaccgcgaag
    33541 tcgccgtact gcaggggcag cggcggcagc accggccgtt ccggcgccgg atccctgcgc
    33601 gacgcggtgt agagccgacc gagctcggag aggagcacgc cgaccgacca tgcgtcggtg
    33661 atcgtatggt gcatggcgac gccgaacagg tggtcccgcg ggcccatccg caccagccgc
    33721 gcccgccaga gcggcgccgc cgtgagatcg aaaccgcgct cgacatcggc cgccaggatc
    33781 cgttcggcgt cggcgcgggg gtcggatacg gccgacaggt cggtcatctc ccagggcaca
    33841 gtcaccgagt cgtggacgat ctgggccgtc cggtcgccgg tccaggccaa ggacgtccgg
    33901 aggatctcgt gtctggcggt caggtcggcg agtccggcgc gtaaccggtc gacgtcgagg
    33961 tcaccgcgca gccgtccggc ggtcgagacg acgtaggccg ccgagtcggg gcggagccgg
    34021 tccagcagcc acagccgctc ctgggagaag gacgcgggca gcggggcgcc ggtgcggggc
    34081 accggccgcg ggtccgccgg gcccgtcgcc gcggcgccgt cccgtgccgg gccgcgcatc
    34141 cggcgcagga cgagttcgcg tgcccgcggg ctgagggcgg cgaggcgctc ggcgcggtcg
    34201 gacggaccgg aggttgcttc actcatgtga cttctcgcct tccgcgagcc tggcggcgat
    34261 ctcttcgtcg gacaggcctg ccacctcgtc caccagtgcg tccaggtcgg ccgcatcgct
    34321 gagcaggcgc tcgaccgcgg cggcgcatcc gctgatggag ggggcggcga acagctccgg
    34381 cagggtgtag tcggccggga aggcctcgcg gatccgcccg acgacgcgga cggccatgag
    34441 ggagtctccg ccgagggtga agaagttgtc gtggaccccg atctccgaaa cgcccagaac
    34501 ctcgctccac aaccccgc
//
