LOCUS       NZ_BMRD01000012        31014 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Actinomadura citrea strain JCM 3295 sequence12, whole genome shotgun
            sequence.
ACCESSION   NZ_BMRD01000012
VERSION     NZ_BMRD01000012.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Actinomadura citrea
  ORGANISM  Actinomadura citrea
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 274361)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: BGI assembly pipeline
            Genome Coverage                   :: 127X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014648455.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 03:26:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,339
            CDSs (total)                      :: 8,265
            Genes (coding)                    :: 8,175
            CDSs (with protein)               :: 8,175
            Genes (RNA)                       :: 74
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 90
            CDSs (without protein)            :: 90
            Pseudo Genes (ambiguous residues) :: 0 of 90
            Pseudo Genes (frameshifted)       :: 12 of 90
            Pseudo Genes (incomplete)         :: 83 of 90
            Pseudo Genes (internal stop)      :: 3 of 90
            Pseudo Genes (multiple problems)  :: 8 of 90
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:33:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 9203
            Orig. end                         :: 40217
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMRD01000012.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..31014
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NI-siderophore"
                     /region_number="1"
                     /rules="IucA_IucC"
                     /tool="antismash"
     cand_cluster    1..31014
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..31014
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[14000:17014](+)"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      14001..17014
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     gene            complement(328..996)
                     /locus_tag="IEZ14_RS25760"
                     /old_locus_tag="GCM10010177_51960"
     CDS             complement(328..996)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012894727.1"
                     /locus_tag="IEZ14_RS25760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_51960"
                     /product="hypothetical protein"
                     /protein_id="WP_218935013.1"
                     /transl_table=11
                     /translation="MTEQVTTGRPQGPARCAAVLAWPSGSAVPPGLDPEDFRLALLEDT
                     YEVVAGLELVTPALVLDPPDQPDAEAVTWPGTPIVREATLAGAFAALHALGAETAALIA
                     PDAPDLPPLLLGKLFRALGTAPAAVCQAEGAAARGNGLVALAARLPLPGWLADALHEVD
                     LDTPDALTRLRAAAPRPGLVPQGPGWHRLRTPDDLRFLDPGLEGWESTRALLEGHPLRG
                     "
     gene            complement(993..1583)
                     /locus_tag="IEZ14_RS25765"
                     /old_locus_tag="GCM10010177_51970"
     CDS             complement(993..1583)
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014908245.1"
                     /locus_tag="IEZ14_RS25765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_51970"
                     /product="M48 family metallopeptidase"
                     /protein_id="WP_229810412.1"
                     /transl_table=11
                     /translation="MPPNVEVRRSPRRRRTVSAYREGDKVVVMVPSRLSKAEEEQWIAT
                     ILERLAERERRRRPTDADLQSRAQELSRRYLAGRADPVSVRWVANQRARWGSCTPDDGT
                     IRLSTRLRGMPGWVVDYVLVHELAHLLIPGHGADFWQLVGNYPKADRARGYLEGVAAAA
                     HLPLEADAPDDVADIHHGDGLHPGEEYPHEAAG"
     misc_feature    complement(1600..1614)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.47"
                     /tool="antismash"
     misc_feature    1601..1614
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.47"
                     /tool="antismash"
     misc_feature    1602..1615
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.45"
                     /tool="antismash"
     misc_feature    complement(1606..1618)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 16.17"
                     /tool="antismash"
     gene            complement(1721..2521)
                     /locus_tag="IEZ14_RS25770"
                     /old_locus_tag="GCM10010177_51980"
     CDS             complement(1721..2521)
                     /NRPS_PKS="Domain: ECH (13-255). E-value: 2.5e-55. Score:
                     179.4. Matches aSDomain:
                     nrpspksdomains_IEZ14_RS25770_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012894729.1"
                     /locus_tag="IEZ14_RS25770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_51980"
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="WP_179833045.1"
                     /transl_table=11
                     /translation="MSAEPADVLVIDRRPDGIAVLTLNDPGRRNAMADDLTAAWKRAVE
                     DLRADPALRCVVVTGAGTAFSSGGELSWLAGTGDVAVPPLRDRMLEFYRTWLAIRGLEV
                     PTIAAVNGHAVGAGLCLALACDLRYAARDAKLLAPFTALGLHPGMAATWLFPEVAGLPL
                     AREMLLAGRVLTGAEAAEHGLVNRALPREDVLEESLAVAARIAAQAPIATRLTKVALAN
                     GGHPDMESALRWESLAQPVTMASKDMREGLAAQREKRRPQFSGE"
     aSDomain        complement(1757..2482)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS25770_ECH.1"
                     /evalue="2.50E-55"
                     /label="IEZ14_RS25770_ECH.1"
                     /locus_tag="IEZ14_RS25770"
                     /protein_end="255"
                     /protein_start="13"
                     /score="179.4"
                     /tool="antismash"
                     /translation="RPDGIAVLTLNDPGRRNAMADDLTAAWKRAVEDLRADPALRCVVV
                     TGAGTAFSSGGELSWLAGTGDVAVPPLRDRMLEFYRTWLAIRGLEVPTIAAVNGHAVGA
                     GLCLALACDLRYAARDAKLLAPFTALGLHPGMAATWLFPEVAGLPLAREMLLAGRVLTG
                     AEAAEHGLVNRALPREDVLEESLAVAARIAAQAPIATRLTKVALANGGHPDMESALRWE
                     SLAQPVTMASKDMREGLAAQ"
     misc_feature    complement(2575..2590)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.8"
                     /tool="antismash"
     gene            2695..4026
                     /locus_tag="IEZ14_RS25775"
                     /old_locus_tag="GCM10010177_51990"
     CDS             2695..4026
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634662.1"
                     /locus_tag="IEZ14_RS25775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_51990"
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="WP_229810413.1"
                     /sec_met_domain="APH (E-value: 1e-07, bitscore: 26.0,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDLPRRAVTRSAKLASLPIGFAGRTALGMGKRTFGRPAETVAME
                     IQTRTAEQLFKVLGELKGGAMKLGQMLSIFEAALPPEIAGPYRATLTRLQEAAPPLPVS
                     TVHKVLEEFLGEDWRDYFESFDDRPAAAASIGQVHRAVWHDGRAVAVKVQYPGAGKALI
                     SDFNQLARLGRLFGVLMPGLDVKSMLAELKERVVEELDYTIEAESQARFREAYLDDPDF
                     AIPEVIAQSGNILITEWMDGTALSKIISDGDQETRDHAALLYCRFLLSGPKRSGMLHGD
                     PHPGNFRLLEDGRLGVLDFGAVDRIPGGFQRRLGLLLRIGTMADIDEVEDALRREDFIR
                     EGVDIDAESLQAFLAPITEPFVTETFKFNREWLRDMAAQVTDLRPSNVVRQLNLPPEYV
                     IIHRVLSAGTGVLCQLECEIPARAESLKWVPGFADDADGELVSG"
     gene            complement(4312..4530)
                     /locus_tag="IEZ14_RS25780"
                     /old_locus_tag="GCM10010177_52000"
     CDS             complement(4312..4530)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEZ14_RS25780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010177_52000"
                     /product="hypothetical protein"
                     /protein_id="WP_179833043.1"
                     /transl_table=11
                     /translation="MTVLSEMTLLSQDLSRERIPATVPDELAARVVALRRARREARTRA
                     SRVRRVLLAPTAAGEAYAHPQRPRHRD"
     gene            complement(4628..4906)
                     /locus_tag="IEZ14_RS25785"
                     /old_locus_tag="GCM10010177_52010"
     CDS             complement(4628..4906)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634664.1"
                     /locus_tag="IEZ14_RS25785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_52010"
                     /product="WhiB family transcriptional regulator"
                     /protein_id="WP_052357680.1"
                     /transl_table=11
                     /translation="MQGALAVSEEDLTLPCRTDPELFFAEAPADVELAKALCLECPLRK
                     ECLAGALERKEPWGVWGGELFVRGVIVPRKRPRGRPRKHPRPDEVAV"
     gene            complement(5026..5412)
                     /locus_tag="IEZ14_RS25790"
                     /old_locus_tag="GCM10010177_52020"
     CDS             complement(5026..5412)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEZ14_RS25790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010177_52020"
                     /product="hypothetical protein"
                     /protein_id="WP_179833042.1"
                     /transl_table=11
                     /translation="MSNTLIKSASSWTAACPGTSMLGTSVSRAPMTRLSKPGESVAYFE
                     ASVIEASALRQRERGMWRRDERGLRGTNLCDLRFEQRIQDDQGRSVFEHLLEDMSAPAP
                     ATAHVGVTFKGGVSGPYPWRRRPV"
     misc_feature    5397..5412
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.29"
                     /tool="antismash"
     misc_feature    5525..5540
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.33"
                     /tool="antismash"
     gene            complement(5631..6527)
                     /gene="tesB"
                     /locus_tag="IEZ14_RS25795"
                     /old_locus_tag="GCM10010177_52030"
     CDS             complement(5631..6527)
                     /GO_function="GO:0047617 - fatty acyl-CoA hydrolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006637 - acyl-CoA metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="tesB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012854059.1"
                     /locus_tag="IEZ14_RS25795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_52030"
                     /product="acyl-CoA thioesterase II"
                     /protein_id="WP_179833041.1"
                     /transl_table=11
                     /translation="MKESLKALLDLLDLEQIENDIFRGRSPEERRQRVFGGQVAGQALV
                     AAGRTVPANRPVHSLHAYFIRPGDPLVPLVYTVDRVRDGRSFTTRRVTAVQHGKAIFTL
                     SASFQVDEDGPSHQAPMPEAPAPETLPDGLTRLTPLFGEVGAREFVTRRPFDIRHATPL
                     SWEAAKDPALATPESKVWLKVDGELPHDPLLHVCLMTYASDMTLLDTVLLNHGLAWGDK
                     RTMGASLDHAMWFHRPFRADDWLLYYQDTPFAGGARGLARGQVFTRSGELVVSVMQEGL
                     IRVSGTEREAPGDPSVR"
     misc_feature    6554..6569
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.24"
                     /tool="antismash"
     gene            complement(6617..8683)
                     /locus_tag="IEZ14_RS25800"
                     /old_locus_tag="GCM10010177_52040"
     CDS             complement(6617..8683)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634666.1"
                     /locus_tag="IEZ14_RS25800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_52040"
                     /product="ATP-dependent DNA helicase UvrD2"
                     /protein_id="WP_179833040.1"
                     /transl_table=11
                     /translation="MSAESVLEGLDPEQRAVAEAVKGPVCVLAGAGTGKTRAITHRIAY
                     ATLTGVVTPQRVLAVTFTTRAAGELRSRLRQLGAPGVQARTFHAAALRQLGYFWPRVVG
                     GEPPKIVDSKIRLVADAARACRLTLGRTELRDVASEIEWAKVTQNRPEDYPAAVVKAGR
                     RPPAEVVDVARVYAMYEQLRRERNLLDFEGMLELTAAVLTEHREVANQVREQYRYFVVD
                     EFQDVNPLQKMLLDTWLGDRDDLCVVGDPNQTIYSFTGASPSHLLDFTREHPDAKVVRL
                     VRDYRSTPQVVRLANGVIGQARGARHKLELVAQRENGPEPVFNEYDDEVAEADDAARRA
                     RKLIEEGVPAREIAILYRINAQSETYESALAAVGVPYVLRGAERFFERPEVREAVVRLR
                     GAARAGADAETDGMGLIQTVRHVLSGAGFSDRPPEGAGAARARWESLAALAQLAEDMAA
                     DNPAAGLTEFVAELEERTVAQHAPPLEGVTLASLHAAKGLEWDAVFLVGLAEGTLPIIY
                     AKTPEQIEEERRLLYVGVTRARVHLNLSWALARSPGGTQARRPSRFLDGLTGKTTTHTP
                     ARVDRTKRRPAKGPQPCRVCGRPLTAAVERKLGRCEDCPSELNEELLLALKEWRAETAG
                     EQKVPAYVVFTDATLQAIAEHAPESREDLARIPGVGRVKLDRYGDAVLGLCGH"
     gene            8812..9102
                     /locus_tag="IEZ14_RS25805"
                     /old_locus_tag="GCM10010177_52050"
     CDS             8812..9102
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017627309.1"
                     /locus_tag="IEZ14_RS25805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_52050"
                     /product="mycoredoxin"
                     /protein_id="WP_173395930.1"
                     /transl_table=11
                     /translation="MATPTTDRAKGAAGQLTMYTTSWCGFCRRLKSQLARDGIQMVEVD
                     IERDPAAADFVMSVNGGNQTVPTLVFPDGTAATNPSAKEVKRRLAQIADAG"
     gene            complement(9164..10096)
                     /gene="nudC"
                     /locus_tag="IEZ14_RS25810"
                     /old_locus_tag="GCM10010177_52060"
     CDS             complement(9164..10096)
                     /EC_number="3.6.1.22"
                     /GO_function="GO:0000210 - NAD+ diphosphatase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="nudC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020544978.1"
                     /locus_tag="IEZ14_RS25810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_52060"
                     /product="NAD(+) diphosphatase"
                     /protein_id="WP_179833039.1"
                     /transl_table=11
                     /translation="MTDAPLESLHAPLEWLALARGTLDRVALNRRDEAWVEAAWADPRT
                     RVLVIQEGQSPVTFEPAPALVLVPPDQAPDGDRWLLGVDGDGVAHFGVNGPLPVIEGAR
                     PAGLRRVGALLGDQDSGLLTHAVALEHWHGTHRYCPRCGARTRVASAGHVRVCPEDGSQ
                     HFPRVDPAVIMLVTDEADRVLLARGPQWPADRRSILAGFVEPGESLEQAVAREVEEEVG
                     LPVRDVRYLGSQPWPLPQSLMLGFTARTDGDLPLRPDPEEILDAAWYTREELRAAIDAG
                     EIVAPGPLSIAAQLIMRWYGGELPKMPPF"
     gene            complement(10117..11502)
                     /locus_tag="IEZ14_RS25815"
                     /old_locus_tag="GCM10010177_52070"
     CDS             complement(10117..11502)
                     /EC_number="3.4.13.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1247: acetylornithine deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018658148.1"
                     /locus_tag="IEZ14_RS25815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_52070"
                     /product="dipeptidase"
                     /protein_id="WP_229810414.1"
                     /transl_table=11
                     /translation="MNDVVAYIQADRDRFVADLKEWLAIPSISGDPAHAEDVRTSAGWL
                     AEYLRGQGFPTVEVWETSGLPAVYAEWPAEDPQAPAVVVYGHHDVQPVEPLEEWETDPF
                     KPVEKGDRLIGRGASDDKGQVFFHTLGLRAALAASGRQSPPVTVKLLVEGEEESGSAHF
                     AELLRTHRDRLACDAVVISDTTMWAADVPSMCTGMRGLAEAEVTLRGPDGDLHSGSFGG
                     AVPNPLHAMASLLAALHDADGRVAVPGFYDDVVPLTDEERELFARLPFDEAEWLRTAGN
                     SRAAHGEKGYTTLERVWARPTAEINGMWGGHTGPGGKTIVPREAHAKISFRLAAGQDPR
                     KVQKQFEAWVAEQAPPGVEAEVRVPAGGVRPCFSPIDSPGVKAARRAMERAFGAEVLFT
                     REGGSGPEADLADILEAPLIFVAVGLDGDRIHAPNEKVEIPLLLKGAETAAYLWEELAA
                     ALR"
     misc_feature    complement(11640..11653)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.86"
                     /tool="antismash"
     gene            11640..11933
                     /locus_tag="IEZ14_RS25820"
                     /old_locus_tag="GCM10010177_52080"
     CDS             11640..11933
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012854063.1"
                     /locus_tag="IEZ14_RS25820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_52080"
                     /product="DUF4031 domain-containing protein"
                     /protein_id="WP_179833037.1"
                     /transl_table=11
                     /translation="MILIDPPLWPARGRVWSHMVSDVSYDELHVFAAELGMPPRAFERD
                     HYDVPSELYEAALLQGAEAVGCQELLLRLTKAGLRRRKAYRPRPVPDGRLGV"
     gene            complement(11930..12538)
                     /locus_tag="IEZ14_RS25825"
                     /old_locus_tag="GCM10010177_52090"
     CDS             complement(11930..12538)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018658150.1"
                     /locus_tag="IEZ14_RS25825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_52090"
                     /product="HD domain-containing protein"
                     /protein_id="WP_179833036.1"
                     /transl_table=11
                     /translation="MDLVDRWVALAGPHTRHIGTELDRRYGESHRRYHTRAHLVAVLDL
                     VDELAGHADDPDAVRIAAWFHDAVYDPERADNEERSARLAARMLADTDVPDAVVARVVR
                     LVELTATHAPEEGDRDGQVLCDADLAVLGAEPERYAAYAAAVREEYAFVPDEFFRAGRA
                     EVLNGLLALPRLFHTPAARERFEERARANVRTELLLLNA"
     misc_feature    12638..12656
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 27.98"
                     /tool="antismash"
     gene            12676..13836
                     /locus_tag="IEZ14_RS25830"
                     /old_locus_tag="GCM10010177_52100"
     CDS             12676..13836
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634673.1"
                     /locus_tag="IEZ14_RS25830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_52100"
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_179833035.1"
                     /sec_met_domain="ATP-grasp_3 (E-value: 5.5e-07, bitscore:
                     23.7, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAASLYLVAGKATDSVTHGFLPAAARLGLDVTLLTDRPSAHDAGV
                     PVVECDVSDFRDIIARVEDGAACGGGEPAAVFSNSDFLQAPAALAAAYFGLPAKDWRAA
                     IRAKNKALMRRHLASLDPVFSADAGRVPAGAPYPLVLKPREGVASEDVFLVHDGGELAA
                     RVEEIRARRGDPLVAEEYLPGRLHTLETLGDGRELRVLGSFRTTLSPPPFFVEERLEWA
                     PPPPETEQVLRQLEALGVGFGACHTEFVVHEGRARVIEVNYRLIGDHCDLLLADLLGVP
                     LFEQILRVHLGASLPERRVPRPRHAVAEPVIADRCGTLTAAPGPVQVEDGAVRLAYRPQ
                     RAVGDTVSLTRTNRDYLGTVRAIGPGPEEVNAALARFRATHDWMIA"
     gene            14001..15416
                     /locus_tag="IEZ14_RS25835"
                     /old_locus_tag="GCM10010177_52110"
     CDS             14001..15416
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (34-64). E-value:
                     0.0015. Score: 11.3. Matches aSDomain:
                     nrpspksdomains_IEZ14_RS25835_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018658152.1"
                     /locus_tag="IEZ14_RS25835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_52110"
                     /product="IucA/IucC family protein"
                     /protein_id="WP_229810415.1"
                     /sec_met_domain="IucA_IucC (E-value: 3.4e-28, bitscore:
                     92.7, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDPGQGLRLSDVFHAVRLIADPGDDTASFERECLEALAAIQLHGE
                     ARPAVHRRLGRLPAELRAGPGTFYETLAAYNDHPVHPTGRSRSGLSPAELSRYAPEFAP
                     SFPLRWAAVRNATRTGSLPGWWPAPSDVGLRSDDAAGALFPVHPLAARQVGPRPGVSLA
                     PDPYLQVTPTLSMRTVAAAPLDHVKMPLPTSTLGVRNRRTIVPGTLPDGALVERILRQV
                     LLREPSLPVLLADEQTYGHADDPLLGYLVRRFPPETARAHIVPVAALLAEAPDRGHVIE
                     RWDVEALFGAYLTALLSFNVTLFRYGIALEAHQQNVALVLDESPVRLLIKDNDGALIDP
                     SRLRERVPPSPGTDPRDLVDRRMTTSDPEALARVFVTITLHLCAAAPALGLAGRGLLPW
                     RTGRRILRERLDGALGPEDAFLRARTLDADTLPGKAMVTAGTLVDKARTGAADINKHYG
                     PPGPNYLLDTTCC"
     aSDomain        14103..14192
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS25835_PKS_Docking_Cterm.
                     1"
                     /evalue="1.50E-03"
                     /label="IEZ14_RS25835_PKS_Docking_Cterm.1"
                     /locus_tag="IEZ14_RS25835"
                     /protein_end="64"
                     /protein_start="34"
                     /score="11.3"
                     /tool="antismash"
                     /translation="EALAAIQLHGEARPAVHRRLGRLPAELRAG"
     misc_feature    14670..14672
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            15407..17014
                     /locus_tag="IEZ14_RS25840"
                     /old_locus_tag="GCM10010177_52120"
     CDS             15407..17014
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012854067.1"
                     /locus_tag="IEZ14_RS25840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_52120"
                     /product="IucA/IucC family siderophore biosynthesis
                     protein"
                     /protein_id="WP_179833033.1"
                     /sec_met_domain="IucA_IucC (E-value: 1.8e-53, bitscore:
                     175.5, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLTEPAVTADDATATALLNCLIREVCGPEQQVWPDGARLVFRLP
                     RAGVLLRAGLARPPVGATRRLAPPFEERREDEWIPAPWDRLANLVAGELELATGSPNAE
                     FLVQVGDSHAALTAILAARGESAEDHSIDYIASEQSLVAGHRFHPSPKARQGSPEEWLP
                     YAPETRARFRPLWLAVPEGLVAEEGAAEAFTTLEAYGPSVPPGRRLLPVHPWQFSLLAD
                     NPVLQRALATGSLVNLGPSEMEAVPTSSVRTAYLPDADVFCKFSLDVRITNCVRKNAWY
                     ELTGAMTLDELLPPILEKLNATFLREPAYRSVALPDRSLYEGLGVILRQGIRSLPGTPL
                     LAGALADPYNALLSGLPALSSPDSAQAWWDAYVAQVAPPVLGAYLDHGVVLEPHLQNVL
                     VCVDTDGMPVHAVFRDMEGTKLTAGHWDLSHLPGRVAEGLTYAPDRGWNRAVYCLLVNH
                     LTEIAAAVADLHPSLDETLWQAARKHFAAFDRHPQVRALLAGVPLPAKANLRTRWSRTA
                     DRGAAYVPVPNPLAARPL"
     gene            17011..18141
                     /locus_tag="IEZ14_RS25845"
                     /old_locus_tag="GCM10010177_52130"
     CDS             17011..18141
                     /EC_number="5.1.1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_DAP_Arg_deC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264: diaminopimelate decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013133203.1"
                     /locus_tag="IEZ14_RS25845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_52130"
                     /product="alanine racemase"
                     /protein_id="WP_179833032.1"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 7.1e-17,
                     bitscore: 55.5, seeds: 500, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 7.9e-27, bitscore:
                     88.1, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEFALNLDRYPAYVYDLPGLESHVRGIRAALPGTEVLYAAKANP
                     DAEILRTLAPHVDGVEVSSGGELAHVRETLPGKPVAFGGPGKTADELALSRTLKADRIH
                     VESPNELARLAALGPADVLLRANLPVNVPNAALTMSGPFGMDEDTLDHCARLLAEYPNI
                     TLRGVHAHLASGLDAPAMLDLAHRTAEWAIPWLRSRGVDDPELNVGGGMAVDYTSPESR
                     FDWQTYGTGLSHIPAKVRIEPGRAMTAYHGWYVTDVLDVKTTRGETYAVLRGGTHHLRT
                     PVTKGHDQPFEVLTANGPERRATLVGQLCTPKDVFARDVLVPPLAPGDVIAFAMAGAYA
                     WNISHHDFLMHPKPAFHYRRRPDAGGSAARAPVPAP"
     gene            complement(18109..18747)
                     /locus_tag="IEZ14_RS25850"
                     /old_locus_tag="GCM10010177_52140"
     CDS             complement(18109..18747)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017625577.1"
                     /locus_tag="IEZ14_RS25850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_52140"
                     /product="maleylpyruvate isomerase N-terminal
                     domain-containing protein"
                     /protein_id="WP_179833031.1"
                     /transl_table=11
                     /translation="MPHSTAAVTADDLDLAVRLAVAALREAPPEAWDGKAGSLEWDCWE
                     TVEHLSDDLFAYAAQLAPRTPPMDGEVPFVWESRRSGGPANAVHADRSAGPAGLLQVLD
                     ACGGMLSAVVRRTAPDVRAHHVFGASDAEGFAAMGIVETLVHMHDLAEGLGLSWEPPAD
                     VCARVLGRLFPGAPQDTDPWPTLLWATGRGDLPGHPRVTSWRWYGSPRG"
     gene            complement(18783..19634)
                     /locus_tag="IEZ14_RS25855"
                     /old_locus_tag="GCM10010177_52150"
     CDS             complement(18783..19634)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017595915.1"
                     /locus_tag="IEZ14_RS25855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_52150"
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="WP_179833030.1"
                     /transl_table=11
                     /translation="MSDIAPALRYTAFDVDGEGGNPAGVVLDARGLEAARMQEIAAEIG
                     FSETAFLVDEGGAPGRFAIRYFSPLAEVAFCGHATIATAVALAERRGTGSLRLSTPAGE
                     VGVETREADGRVLATLTSVPPTVRAVEEADLAAALDALRWEAGELDPELPPRIANAGND
                     HLVLAASTRARLAGLDYDGDALGGLMARRGWTTVHLVWRESATVFHARDPFPPGGVVED
                     PATGAAAAAFGGYLRSLGLVAPPARITVHQGEDMGRPSRLLVDVPPGDTGIGVSGTAAP
                     MG"
     gene            19706..20623
                     /locus_tag="IEZ14_RS25860"
                     /old_locus_tag="GCM10010177_52160"
     CDS             19706..20623
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1031: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015431.5"
                     /locus_tag="IEZ14_RS25860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_52160"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_179833029.1"
                     /transl_table=11
                     /translation="MDTRLLTTFLAVLRNGGMTAAAAELGFVQSTVTAHVQALERLAGT
                     PLLDRLPGGVSPTRAGSLLAEHARGVLDLQERMLAEVTAAATEPSGPVRLRAPESVCAY
                     WLAPLLPRLRARLPDVTVSLFPADTRTALTALADRGADVALILDPSPDPSGVDLVDLGA
                     QPLSLVAAVSTPLPRNRPLTPAELAATGIVLLEEGCSYSDEFAALVTAARPTANPPRFG
                     GIETAKRCVAAGLGAALLPTVTVADELAAGALAELTPPAGLSRHHLWLAEPASRWRSPA
                     VHALRTALIDSITGPGAPGSPPRP"
     gene            20684..20827
                     /locus_tag="IEZ14_RS25865"
                     /old_locus_tag="GCM10010177_52170"
     CDS             20684..20827
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEZ14_RS25865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010177_52170"
                     /product="hypothetical protein"
                     /protein_id="WP_218935011.1"
                     /transl_table=11
                     /translation="MAAAAPGAERLVEFTVTGVVETAGASPLRWSDPVPSRVNPPAALN
                     LP"
     misc_feature    20706..20721
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.27"
                     /tool="antismash"
     gene            20851..21774
                     /locus_tag="IEZ14_RS25870"
                     /old_locus_tag="GCM10010177_52180"
     CDS             20851..21774
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890858.1"
                     /locus_tag="IEZ14_RS25870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_52180"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_179833028.1"
                     /transl_table=11
                     /translation="MDGEATYSIGELARSAGVTVKAVRFYTERGIVPARRTAAGHRRYG
                     ADAVARLGLVRTLRELGIDLATVQKIVDREVRAADAAAAHAEAVAAQMRMLRLRHAVLT
                     IAARRGSDPEEMELMHRLARLSAAERDDLVADFLDSSFGTPDAGPMSRVLHRSLAPELP
                     DDPTSEQLAAWVELAELTRDPGFRALMRGLFDDHATEAARRTGPPRKHAVARVAETVRP
                     LLAAGAAPDSPRAAQAVTDVVAAYAEFQGRPDTPALRARLATYLTSANDPRRERYLHLL
                     STVNDWSPPDHPRHELDWFLAALTSS"
     misc_feature    20869..20883
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.52"
                     /tool="antismash"
     gene            21892..23481
                     /locus_tag="IEZ14_RS25875"
                     /old_locus_tag="GCM10010177_52190"
     CDS             21892..23481
                     /NRPS_PKS="Domain: AMP-binding (54-436). E-value: 5.9e-67.
                     Score: 217.9. Matches aSDomain:
                     nrpspksdomains_IEZ14_RS25875_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012850934.1"
                     /locus_tag="IEZ14_RS25875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_52190"
                     /product="AMP-binding protein"
                     /protein_id="WP_229810443.1"
                     /sec_met_domain="AMP-binding (E-value: 3.1e-71, bitscore:
                     234.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLERVRGAAEAGVRAARAVRDAGVVRPVRPDRAARLLFPYVRFGP
                     VPATLGAMAALRFPDRTALIDERGALSYAELERRAAALATALSGRVGDGKVGILCRNHR
                     GFVETVLAATRLGNDVVLLNTDFSGRQLGQVVEREEIELLVHDEEFGPAVEESGFAGKR
                     VVAWADGGGAIDALIEETAPEPVKPERASRVILMTSGTTGTPKGARHDLSASSLLPAAL
                     SHLMRVPVRSGAPMVIGPPLFHLLGFAYTTVGLAMGMPLVLSRRFDPRQVLETIADSRA
                     EALVAVPVMLQRVLDVRDAPPTPALRAVVCGGAALHPHLSEAFMDAFGDVLVNVYGATE
                     TGWATIATPEDLRAAPGTVGRPSFRLTIKVLGEDGRELPAGETGEVYTGGGLRFAGYTG
                     GGGRRVRDGLTGTGDLGHFDAAGRLFIDGRADDMIVSGGENVFPGEVENLLGGHPDVAE
                     VSVTGVDDERFGQRLAAHVVRTEGAEVAEDDLREYVRAHLARYKVPRDIRFVRELPRTS
                     TGKVKRRPDGGR"
     aSDomain        22054..23199
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS25875_AMP-binding.1"
                     /evalue="5.90E-67"
                     /label="IEZ14_RS25875_AMP-binding.1"
                     /locus_tag="IEZ14_RS25875"
                     /protein_end="436"
                     /protein_start="54"
                     /score="217.9"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="ALRFPDRTALIDERGALSYAELERRAAALATALSGRVGDGKVGIL
                     CRNHRGFVETVLAATRLGNDVVLLNTDFSGRQLGQVVEREEIELLVHDEEFGPAVEESG
                     FAGKRVVAWADGGGAIDALIEETAPEPVKPERASRVILMTSGTTGTPKGARHDLSASSL
                     LPAALSHLMRVPVRSGAPMVIGPPLFHLLGFAYTTVGLAMGMPLVLSRRFDPRQVLETI
                     ADSRAEALVAVPVMLQRVLDVRDAPPTPALRAVVCGGAALHPHLSEAFMDAFGDVLVNV
                     YGATETGWATIATPEDLRAAPGTVGRPSFRLTIKVLGEDGRELPAGETGEVYTGGGLRF
                     AGYTGGGGRRVRDGLTGTGDLGHFDAAGRLFIDGRADDMIVS"
     CDS_motif       22474..22515
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS25875_0001"
                     /evalue="1.30E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="IEZ14_RS25875"
                     /protein_end="208"
                     /protein_start="194"
                     /score="14.9"
                     /tool="antismash"
                     /translation="ILMTSGTTGTPKGA"
     gene            complement(23536..23844)
                     /locus_tag="IEZ14_RS25880"
                     /old_locus_tag="GCM10010177_52200"
     CDS             complement(23536..23844)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634678.1"
                     /locus_tag="IEZ14_RS25880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_52200"
                     /product="hypothetical protein"
                     /protein_id="WP_179833026.1"
                     /transl_table=11
                     /translation="MGSSTVRALDREPAALAMRIGVVAAEAALATFARNLDLDDLADGV
                     DFQGAIGPAEWPVFSLVIDTLAEAGPGDHRTLDERRADALNDLARICMAAKRRAGAA"
     misc_feature    23835..23849
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.29"
                     /tool="antismash"
     misc_feature    23835..23850
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.94"
                     /tool="antismash"
     misc_feature    complement(23836..23849)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.71"
                     /tool="antismash"
     misc_feature    23878..23893
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.23"
                     /tool="antismash"
     misc_feature    complement(23879..23892)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.26"
                     /tool="antismash"
     misc_feature    23892..23903
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.03"
                     /tool="antismash"
     gene            complement(23899..24678)
                     /locus_tag="IEZ14_RS25885"
                     /old_locus_tag="GCM10010177_52210"
     CDS             complement(23899..24678)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634679.1"
                     /locus_tag="IEZ14_RS25885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_52210"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_179833025.1"
                     /transl_table=11
                     /translation="MSVSHDEKVVREFSKQAAGFSDPRLNTAFTRHLDRLVRFMDPELD
                     LEDVVLEVAAGTGIVSRAIARRVRHVTALDLTPAMLAEGKRDADHAGLTNVTFAHGDAT
                     ALPYLDRSFTLVVTRFSLHQVADPGAVVTEMARVSRPGAALIIADLVRPEGLDGDPDRI
                     ERLRDPSHGAALTEARIAELVTAAGAAVKRADRFDHSRPLDPWLEFSHTPSDAAAQIRR
                     ELEEELAGGPATGMRPSMVDGALHFTHSYLFQQAIVG"
     gene            complement(24752..28324)
                     /locus_tag="IEZ14_RS25890"
                     /old_locus_tag="GCM10010177_52220"
     CDS             complement(24752..28324)
                     /EC_number="3.6.4.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017541791.1"
                     /locus_tag="IEZ14_RS25890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_52220"
                     /product="ATP-dependent DNA helicase"
                     /protein_id="WP_179833024.1"
                     /transl_table=11
                     /translation="MITPGELARLLEIPAPTEEQARVIEAPMAPMAVIAGAGSGKSETM
                     AARVVWLVANGFVRPERVLGLTFTRKAAAELGVRVRKRLDRLREVLPGDELERLGGEAL
                     FDGEPMVSTYHSYAARLFGDHALREALEPTMRLISPAVAWQICSRVVDAYHGPMDRIDW
                     QPDTVTKAVMELSGDLSEHLRTAEDVRRVGAWLDERLAVVKKPLKAQRDILAKHAVREQ
                     LMPLIEAYGRAKADREVIDHGDQMALAARIAYKHPEVGMIERSRFSVVLLDEYQDTSQA
                     QLVLLTSLFAGGHPVTAVGDPCQSIYGWRGASAGNLLRFAHDFPLQPAAAPGGRPVAAP
                     VVQLSRSFRNGEQILEAAARVQEELRAETRSVPRLIPGAGREGRGRVECALFPTVEDEA
                     DRVAARIAGLMAGDPETAPDGGPQAEPLRYSDVAVLARKRSQFPLIRRALEARGIPVEV
                     VGLGGLLTVPEVQDVVATLRVMHDPTAGASLARLLTGPRWRLGPRDLVALGRRARALAQ
                     ESARDITRPDPVPAAAPEEGPGPAAPGEGLGPASGSVLGSVSTAEPDPASAAAPGPASG
                     ATSGDESGAAPREGADDASDAAFGVASVEGAGEGDGGDDPLRQLVSELNQETGSLVDAL
                     DDLGPPDAFSPEGYGRLRRLRDELRALRGQVGLPLPDLANEVERALGLDIEVAARSGLD
                     PVTARADLDAFIDAAATFAGDAEDPTLGAFLAYLKAAETEEFGLEAGRVGETDSVKLLT
                     VHASKGLEWPVVVVPGLAYTPQKNGSPAKGSIFPSPPQNATRWTANPRVLPFMLRGDRA
                     DLPALTGLEKDDLSVFDQACSERDLREERRLAYVAVTRASSLLITTGYWWGSSGRPLGP
                     SPFLEEVRAVCLAGAGSVAVWADPPEEGAANPLLADPEEAQWPIAPGERGRSDLSARAR
                     YEAVVEGARMVEDEMAGRTRHWAGDTGLSDADRGRMTAWARDVELLLAERDRGRGGDGL
                     LVELPAHLSVSSLVSLARDPAALARQIRRPMPRPPAPYARRGTAFHTWLEGRWGQQRLL
                     DPDELPGAADEGAADDAHLATLRERFERSEWAAREPLDIEVPFETIIGDRLVRGRMDAV
                     FRSRDGGYEVVDWKTGAPPRGDEARFSAVQLAAYRLAWAELAGVDVARVSAAFHYVSAE
                     VTVRPADLLDAAGLAALLDGVPAA"
     misc_feature    30152..30166
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.35"
                     /tool="antismash"
     misc_feature    30670..30685
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.84"
                     /tool="antismash"
ORIGIN
        1 gcagatggac tcagctcggc ggccactgcg agaccggcga cgccgacctc gtcgcggcgg
       61 cgcggcggga ggccgccgag gagtccggca tcccgggcat cgaggtggag ccctcccccc
      121 tccggctcga tcgctatcgt gctcgctgcc gtggccggga cctgctgcat ttcgacgtgc
      181 agttcgcggc gacggccccg ccccgggcgg tgccggagcc tgcggccggc ggggacgagg
      241 cgcggtggtt cccggtgcct gccctgccct tctcggcgga cgagtccacg cgaagcctgg
      301 tccggcacgc cctggcccgg cgtgggctca acccctgagc gggtggcctt ccaggagggc
      361 gcgggtgctc tcccagcctt ccaggccggg gtccaggaac cgcaggtcgt cgggggtgcg
      421 gaggcggtgc cagccggggc cctgcggcac gagcccgggg cgcggcgcgg cggcgcggag
      481 ccgggtgagg gcgtcggggg tgtcgaggtc gacctcgtgc agggcgtcgg cgagccagcc
      541 gggcagcggg agccgggcgg cgagggcgac caggccgttg ccgcgggcgg cggcgccttc
      601 ggcctggcag acggcggccg gggccgtgcc gagggcgcgg aagagcttgc cgagcagcag
      661 cggcggcagg tcgggggcgt cgggggcgat cagcgcggcg gtctcggcgc cgagggcgtg
      721 cagggcggcg aacgcgccgg cgagggtggc ctcgcggacg atcggcgtgc ccggccaggt
      781 gacggcctcg gcgtccggct ggtccggcgg gtccaggacg agcgcgggcg tcaccagttc
      841 gagtccggcg acgacctcgt aggtgtcttc gagcagcgcg agccggaaat cctccgggtc
      901 gaggccgggc ggcacggcgg agccggacgg ccacgcgagc acggcggcgc agcgcgccgg
      961 gccttgcggc cgccccgtgg tgacctgctc ggtcacccgg cggcctcgtg cgggtactcc
     1021 tcgccggggt gcaggccgtc gccgtggtgg atgtccgcga cgtcgtcggg ggcgtccgct
     1081 tcgagcggca ggtgggcggc cgcggcgacg ccctccaggt agccgcgggc gcggtcggcc
     1141 ttggggtagt tgccgaccag ctgccagaag tcggcgccgt gcccggggat gagcaggtgc
     1201 gccagctcgt ggacgaggac gtagtccacg acccagccgg gcatgccgcg cagccgcgtg
     1261 gacagccgga tcgtgccgtc gtcgggggtg cacgatcccc agcgggcgcg ctggttggcg
     1321 acccagcgga cgctgaccgg gtcggcgcgg ccggccaggt agcggcggga cagctcctgg
     1381 gcgcgggact ggaggtcggc gtcggtgggc cgccgccggc gctccctctc cgcgaggcgt
     1441 tccaggatgg tcgcgatcca ctgttcctct tcggccttgc tcagcctgga cggaaccatc
     1501 accaccacct tgtcgccctc acggtaggcg gacacggtgc gcctgcgcct cgggctgcgg
     1561 cggacctcaa cgttaggggg cacggtcaga accgtactcg aatttttgcc aaatccacag
     1621 ggggtgttgg acgttaccgc aggtcaaccc ctacgttttg gacagttctc caacgcttcc
     1681 accaatctcg gccgacggtt ccggagaccg cccgcgcact ttactcgcct gagaattgcg
     1741 ggcggcgctt ctctcgctgg gccgcgagcc cttcgcgcat gtccttggac gccatcgtca
     1801 ccggctgggc gagggactcc cagcgcagcg ccgactccat gtcggggtgg ccgccgttcg
     1861 ccagggcgac cttggtgagc cgggtcgcga tcggcgcctg cgccgcgatc cgcgcggcga
     1921 cggcgaggga ctcctccagc acgtcctcgc gcgggagggc ccggttgacc aggccgtgct
     1981 cggcggcctc ggcaccggtg aggacccgtc cggccagcag catctcgcgg gccagcggca
     2041 gcccggcgac ctcggggaac agccaggtcg cggccatgcc ggggtgcagg ccgagcgcgg
     2101 tgaacggggc gagcagcttg gcgtcgcgcg ccgcgtaccg caggtcgcag gccagcgcga
     2161 ggcagaggcc ggcgccgacg gcgtgcccgt tgacggcggc gatcgtcggc acctccaggc
     2221 cgcggatcgc gagccacgtc cggtagaact ccagcatccg gtcgcgcagc ggcgggacgg
     2281 cgacgtcgcc ggtgccggcc agccaggaca gttcgccgcc ggagctgaac gcggtgccgg
     2341 cgccggtcac gacgacgcag cgcagggccg ggtcggcgcg caggtcctcg acggcccgct
     2401 tccacgcggc ggtgaggtcg tccgccatgg cgttgcggcg gccggggtcg ttcagggtga
     2461 ggacggcgat cccgtcggga cggcggtcga tcactagcac atcggcaggc tccgcggaca
     2521 tgtccggcac cgtaccgcgc ccgccggggc gcgcggcgcg cggcccctcc tacgcgtgag
     2581 aaagcgcaca cttaccgcat ttacccagct cagccgggtg ggccggttcc ggcttcgggg
     2641 agagttcggg agggttgtgg cgtgcacgac agtggatcat cgacaatggt cgatgtgagc
     2701 gatcttcccc gccgcgcggt gacgcggtca gcaaagctgg cgtccctccc catcggcttc
     2761 gcgggacgca ccgccctcgg catggggaag cggaccttcg gccggccggc ggagacggtc
     2821 gcgatggaga tccagacccg gaccgccgag cagctgttca aggtgctcgg cgagctcaag
     2881 ggcggcgcga tgaagctcgg ccagatgctg tcgatcttcg aggcggcgct tccaccggag
     2941 atcgccggcc cgtaccgggc cacgctgacc aggctgcagg aggccgctcc cccgctgccg
     3001 gtgtcgaccg tccacaaggt gctggaggag ttcctcgggg aggactggcg cgactacttc
     3061 gagtcgttcg acgaccggcc ggccgccgcc gcgtcgatcg gccaggtgca ccgcgccgtc
     3121 tggcacgacg gccgggccgt cgcggtgaag gtgcagtacc cgggcgcggg caaggcgctg
     3181 atcagcgact tcaaccagct cgcccggctg ggccggctgt tcggggtgct gatgccgggc
     3241 ctggacgtca agtcgatgct ggccgagctc aaggagcggg tggtcgagga gctcgactac
     3301 acgatcgagg ccgagtcgca ggcgcggttc cgcgaggcct acctggacga ccccgacttc
     3361 gccatccccg aggtcatcgc gcagtccggc aacatcctga tcaccgagtg gatggacggc
     3421 accgcgctct cgaagatcat cagcgacggg gaccaggaga cccgcgacca cgcggccctg
     3481 ctgtactgcc ggttcctgct gtcgggaccg aagcggtcgg ggatgctgca cggcgacccg
     3541 caccccggca acttccggct gctggaggac ggccggctcg gcgtcctgga cttcggcgcc
     3601 gtcgaccgca ttcccggcgg gttccagcgc cggctcgggc tgctgctgcg gatcggcacg
     3661 atggccgaca tcgacgaggt cgaggacgcc ctgcgccggg aggacttcat ccgcgagggc
     3721 gtggacatcg acgccgagtc gctccaggcg ttcctcgcac cgatcaccga gccgttcgtc
     3781 accgagacgt tcaagttcaa ccgcgagtgg ctgcgcgaca tggccgccca ggtcaccgac
     3841 ctgcgcccct ccaacgtcgt ccggcagctg aacctgccgc ccgagtacgt gatcatccat
     3901 cgggtgctgt cggcgggcac cggcgtgctg tgccagctcg agtgcgagat cccggcccgt
     3961 gccgagtcgc tgaagtgggt gcccggcttc gccgacgacg cggacggcga gctggtcagc
     4021 ggctgaccgc tccacccggg aggcgccgca cgcggaggcg ccggcacccg gagaagcccg
     4081 ggggccccgc gcactgatga ggtgggcggg gccccgctct tcacgcgtcc ggtgagtggg
     4141 ccaccggacg cgctccacgc gcccgccggg aggcgtgccg tccgccaaac catccaagaa
     4201 agaacggacg gcggcctgcg accggcgagc tctgcgtctt tcagtcctgc tgtgtctttc
     4261 agtcctgctt cgtctctcgg tcctgcttct ctctggggcg cggtcggtcg gtcagtcccg
     4321 gtgccgcggc cgctgcgggt gcgcgtacgc ctcgccggcc gcggtgggcg cgagcaggac
     4381 gcgccgcacc cgcgacgccc tggtccgcgc ctcccggcgg gcgcgcctga gcgcgaccac
     4441 gcgggcggcg agctcgtcgg gcacggtcgc gggtattcgc tcccgggaca ggtcctggct
     4501 gagcaacgtc atctcgctga gcaccgtcat ctcgttctct ccggccgccc ggaggcgcgg
     4561 tccccgcgcg ggggccgcgc ctccggaatc ggtccggccg atcaccggcg tggtgggcat
     4621 ggtcgcctca caccgccact tcgtcggggc gcgggtgctt gcgcgggcgg ccgcgcggcc
     4681 gcttgcgcgg cacgatcaca ccgcggacga acagttcgcc gccccagacg ccccagggct
     4741 ccttgcgctc cagcgccccg gcgaggcact ccttgcggag cgggcactcc aggcacaggg
     4801 ccttggcgag ctcgacgtcg gcgggagcct cggcgaagaa cagctccggg tcggtccggc
     4861 acggaagcgt gaggtcctcc tcgcttactg cgagagcccc ctgcatcaca gtcacccttg
     4921 ttcctctcgt tggatctcaa cgggcgtgtc ggtgggtctg gacaaagaag aaggccgcgg
     4981 atccggtgtc tggatccgcg gcctgggggc ttgccggtct tcgttctaga ccggtcgtcg
     5041 cctccagggg tacggacccg acacgccacc cttgaaggtg acgcccacgt gggccgtggc
     5101 cggagccgga gcgctcatgt cctcgagaag gtgttcgaag acactgcgcc cctggtcgtc
     5161 ctggattcgc tgctcgaagc gcagatcgca cagattcgtg ccgcgcagcc cgcgctcgtc
     5221 gcgccgccac atgccgcgct cacgctgtcg cagggcggac gcctcgatga cggacgcctc
     5281 gaaatacgcg acggactcgc cgggcttcga gagacgggtc atcggggcgc gggacacgga
     5341 ggtgccgagc atcgaggtgc cggggcaggc cgcggtccag gacgacgcgg atttgatcaa
     5401 cgtgttgctc accggactgc acaccacctc tctggctcct cgggccgggc cggcggattc
     5461 aagatccaca ccggtcggcc ggttgattgc tcgcgtcgag cgtacgggga ctccgccgga
     5521 tcaagcaaga tatttttgac ctgcggtttc gtgggggact tcaccctcgt tccgcagaac
     5581 cccgggcgcc tcgcgagcgt cgaaactccc gggagccccg tacggaacga tcatctcacg
     5641 gacgggtcac cgggcgcctc gcgttcggtg cccgagacgc ggatgaggcc ctcctgcatg
     5701 acggacacca ccagctcccc cgagcgggtg aacacctggc cgcgggcgag cccgcgggcg
     5761 ccgccggcga acggcgtgtc ctggtagtac agcagccagt cgtcggcgcg gaacggacgg
     5821 tggaaccaca tcgcgtggtc gaggctggca cccatcgtcc gcttgtcgcc ccaggccagc
     5881 ccgtggttga gcaggacggt gtcgagcagc gtcatgtccg aggcgtaggt catgaggcac
     5941 acgtgcagga gcgggtcgtg cggcagctcc ccgtccacct tgagccacac cttcgactcg
     6001 ggcgtggcca gggcggggtc cttggccgcc tcccacgaca gcggcgtcgc gtgccggatg
     6061 tcgaacgggc ggcgggtgac gaactcgcgc gcgccgacct cgccgaacag cggcgtgagg
     6121 cgggtcaggc cgtccggcag cgtctccggg gcgggggcct ccggcatcgg ggcctggtgg
     6181 gacgggccgt cctcgtcgac ctggaacgac gccgacagcg tgaagatcgc cttgccgtgc
     6241 tggacggcgg tgacgcggcg ggtggtgaag gaccgcccgt cccggacccg gtcgacggtg
     6301 tagacgaggg ggaccagcgg atcgccgggc cggatgaagt aggcgtgcag cgagtggacg
     6361 ggccggttcg ccgggacggt gcgcccggcg gcgacgagcg cctgccccgc cacctgcccc
     6421 ccgaacacgc gctgccgccg ctcctcgggg ctgcggcctc ggaagatgtc gttctcgatc
     6481 tgctccaggt cgagcaggtc cagcagtgcc ttcagcgatt ccttcacggc ggcaagtctt
     6541 ccctatcggt gcgtgtgagc cggctctcac cccgcggcgc cggcccccct cggcgcccag
     6601 ccccgcccgg gcggcgtcag tgcccgcaga ggccgaggac ggcgtcgccg tagcggtcga
     6661 gcttgaccct gccgacgccc gggatgcggg ccaggtcctc ccgggactcg ggggcgtgct
     6721 cggcgatcgc ctggagcgtc gcgtccgtga acaccacgta cgcgggcacc ttctgctcgc
     6781 ccgccgtctc ggcgcgccac tccttgagcg cgaggaggag ctcctcgttc agctcggagg
     6841 ggcagtcctc gcagcggccc agcttgcgct cgacggcggc ggtcagcggg cgcccgcaca
     6901 cgcggcacgg ctgcggcccc ttggcgggac gccgcttcgt ccggtcgacg cgcgcgggcg
     6961 tgtgcgtggt ggtcttgccg gtcaggccgt ccaggaagcg ggacgggcgg cgcgcctgcg
     7021 ttccgccggg cgagcgcgcc agcgcccacg acaggttcag gtgcacgcgg gcccgcgtca
     7081 cgccgacgta gaggaggcgg cgctcctcct cgatctgctc gggcgtcttg gcatagatga
     7141 tgggcagcgt gccctcggcc agcccgacga ggaacaccgc gtcccactcc aggcccttgg
     7201 cggcgtgcag cgaggcgagc gtgacgccct ccagcggcgg cgcgtgctgc gcgacggtgc
     7261 gctcctccag ctcggcgacg aactcggtga gcccggccgc ggggttgtcg gcggccatgt
     7321 cctcggcgag ctgcgccagc gccgccaggg actcccagcg cgcgcgggcc gcgcccgcgc
     7381 cctcgggcgg ccggtcggag aaccccgccc cgctcaggac gtgccggacg gtctggatca
     7441 gccccatccc gtcggtctcg gcgtcggcgc ccgcccgcgc cgcgccgcgc agccggacca
     7501 cggcctcgcg cacctcgggc cgctcgaaga agcgctccgc gccgcgcagc acgtacggga
     7561 cgcccacggc cgcgagcgcc gactcgtacg tctcggactg cgcgttgatc cggtagagga
     7621 tcgcgatctc cctggcgggg acgccctcct cgatcagctt gcgggcccgc cgggcggcgt
     7681 cgtcggcctc ggcgacctcg tcgtcgtact cgttgaacac gggctcgggc ccgttctcgc
     7741 gctgcgcgac cagctccagc ttgtgccgcg ccccccgcgc ctgcccgatc accccgttcg
     7801 ccagccggac gacctgcggc gtcgagcggt agtcgcggac gagcctgacg accttggcgt
     7861 ccgggtgctc gcgggtgaag tcgagcaggt gggaggggga cgcgccggtg aaggagtaga
     7921 tcgtctggtt ggggtcgccg acgacgcaca ggtcgtcgcg gtcgccgagc caggtgtcga
     7981 gcagcatctt ctgcaggggg ttgacgtcct ggaactcgtc cacgacgaag taccggtact
     8041 gctcacggac ctggttggcg acctcgcggt gctcggtgag gacggcggcg gtcagctcca
     8101 gcatgccctc gaagtcgagc aggttgcgct cgcgcctgag ctgctcgtac atcgcgtaga
     8161 cgcgggccac gtcgacgacc tcggcgggcg gccggcggcc cgccttcacg accgcggccg
     8221 ggtagtcctc ggggcggttc tgggtgacct tcgcccactc gatctcgctc gcgacgtcgc
     8281 gcaactcggt gcggccgagc gtgagccggc acgcccgcgc cgcgtccgcg accagccgga
     8341 tcttcgagtc gacgatcttc ggcggctcgc cgccgacgac gcgcggccag aagtagccga
     8401 gctgccgcag agcggcggcg tggaacgtgc gggcctgcac gcctggcgcg ccgagctgcc
     8461 gcagccggct gcgcagctct cctgccgccc gtgtggtgaa cgtcacggcg agcacccgct
     8521 gcggggtcac gacgccggtg agggtggcgt aggcgatccg gtgggtgatg gccctggtct
     8581 tgcccgtccc ggcgcccgcg aggacgcaga ccgggccctt caccgcttcg gcgaccgccc
     8641 gctgctcggg gtccaagccc tccagcaccg actcagctga cattccccca tactcgcagc
     8701 ccgcctcacc tgtatcagcc atcccgccgc ctgtggacaa cgcggaatgg gaaacggctg
     8761 tctactgttc ttgcggaggc acacccccga gcgcaaggag acgcggaagc gatggcgacg
     8821 ccgacgaccg accgggccaa gggcgcggcc ggccagctca ccatgtacac gacgtcctgg
     8881 tgcgggttct gccggcggct gaagagccag ctggcccgcg acggcatcca gatggtggag
     8941 gtcgacatcg agcgcgaccc cgcggccgcc gatttcgtga tgagcgtcaa cggcgggaac
     9001 cagacggtcc cgaccctggt gttccccgac ggcacggccg cgaccaaccc cagcgccaag
     9061 gaggtcaagc gccgcctcgc gcagatcgcc gacgcgggct gagacccgag gagaaggccc
     9121 gccgacccgg acggtcggcg ggcctttccg cgtgcgcgtg cccctagaac ggcggcatct
     9181 tggggagttc gccgccgtac cagcgcatga tgagctgggc ggcgatggac agcgggcccg
     9241 gtgcgacgat ctcgcccgcg tcgatggcgg cgcgcagctc ctcgcgcgtg taccaggcgg
     9301 cgtccaggat ctcctcgggg tcggggcgca gcgggaggtc cccgtccgtc cgcgcggtga
     9361 acccgagcat gaggctctgc ggcagcggcc acggctggct gccgaggtag cggacgtccc
     9421 ggacgggcag cccgacctcc tcctccacct cccgcgcgac ggcctgttcg agcgactcgc
     9481 ccggttcgac gaacccggcg aggatcgagc ggcggtcggc gggccactgc gggccgcggg
     9541 ccagcagcac gcggtcggcc tcgtccgtca ccagcatgat cacggcgggg tcgacgcgcg
     9601 ggaagtgctg cgagccgtcc tcggggcaga cgcgcacgtg cccggcggac gccacgcgcg
     9661 tccgggcgcc gcaccgcggg cagtaccggt gggtgccgtg ccagtgctcc agggcgacgg
     9721 cgtgggtgag caggccggag tcctggtcgc cgaggagggc gccgacgcgg cggagccccg
     9781 ccggccgcgc cccctcgatg acgggcagcg ggccgttcac cccgaagtgg gcgacgccgt
     9841 cgccgtcgac gccgaggagc caccggtcgc cgtccggcgc ctggtccggc gggacgagga
     9901 ccagcgcggg agcgggctcg aaggtgaccg gcgactgacc ttcctggatg accagtacgc
     9961 gcgtcctggg gtccgcccac gccgcttcca cccaggcctc gtcgcggcgg ttcagcgcga
    10021 cgcggtccag cgtgccgcgc gcgagcgcta gccattccag cggggcgtgc agactctcca
    10081 gcggggcgtc ggtcatcgtg ctcctctccg gcgtgttcag cgcagcgcgg ccgcgagttc
    10141 ttcccacagg tacgcggcgg tctcggcgcc cttgagcagc agcgggatct cgaccttctc
    10201 gttgggggcg tggatgcggt cgccgtccag cccgaccgcg acgaagatca gcggcgcctc
    10261 caggatgtcg gcgaggtcgg cctcggggcc gctgccgccc tcgcgggtga acagcacctc
    10321 ggcgccgaac gcccgctcca tggcgcgccg cgcggccttc acgccgggcg agtcgatcgg
    10381 cgagaagcag ggccggaccc cgccggccgg gacgcggacc tcggcctcga cgccgggcgg
    10441 cgcctgctcg gcgacccacg cctcgaactg cttctggacc ttgcgggggt cctgcccggc
    10501 ggcgagccgg aacgagatct tggcgtgcgc ctcgcgaggg acgatcgtct tgccgcccgg
    10561 gccggtgtgc ccgccccaca tgccgttgat ctcggcggtc ggccgggccc agacccgttc
    10621 gagggtcgtg tagcccttct cgccgtgggc ggcgcggctg ttaccggcgg tgcgcagcca
    10681 ctcggcctcg tcgaacggca gccgggcgaa cagctcccgc tcctcgtcgg tcagcgggac
    10741 gacgtcgtcg tagaagccgg ggacggcgac gcggccgtcg gcgtcgtgca gggcggcgag
    10801 cagcgaggcc atcgcgtgga gcgggttggg gacggcgccg ccgaacgagc cggagtgcag
    10861 gtcgccgtcc gggccgcgca gcgtgacctc ggcctcggcg agaccgcgca tgccggtgca
    10921 catggacggc acgtccgccg cccacatggt ggtgtcgctg atgacgacgg cgtcgcaggc
    10981 gagccggtcg cggtgggtgc gcagcagctc ggcgaagtgc gccgagccgg actcctcctc
    11041 gccctcgacc agcagcttga cggtgacggg cggggactgc cgcccggacg cggcgagcgc
    11101 cgcgcgaagg ccgagggtgt ggaagaagac ctggcccttg tcgtcggacg cgccgcgccc
    11161 gatgagccgg tcgcccttct cgacgggctt gaacgggtcg gtctcccact cctccagcgg
    11221 ctcgaccggc tggacgtcgt ggtgcccgta gacgacgacc gccggggcct gcgggtcttc
    11281 ggcgggccat tcggcgtaca ccgccggcag gccggaggtc tcccagacct cgacggtggg
    11341 gaagccctgg ccgcgcaggt actccgcgag ccatccggcg gaggtgcgca catcctcggc
    11401 gtgcgccggg tccccggaga tggacgggat cgccagccac tccttgagat cggcgacgaa
    11461 ccggtcgcgg tccgcctgga tgtaggcgac aacatcgttc acctgcatgc cccttcgcat
    11521 gtcgtaatgt cgggctgagt gacctctgtc cgggatctcc ggacgtcccg acccctcggg
    11581 ttccccgaga ctggagaatc acagtaaggg atcaccttgc ctcgatcgcg ggagtggcct
    11641 tgatcctcat cgacccgccg ctgtggcccg cgcggggacg cgtgtggtcg cacatggtca
    11701 gtgacgtgtc ctacgacgag ctgcacgtgt tcgccgcgga actggggatg ccgccgcggg
    11761 cgttcgagcg cgaccactac gacgtcccgt cggagctcta tgaggcggcg ctgctccagg
    11821 gcgccgaggc ggtgggctgc caggagctgc tcttgcggtt gaccaaggcg ggcctgcgcc
    11881 gccgcaaggc gtaccggccc cggccggttc cggacggccg gctgggcgtc taggcgttga
    11941 ggagcaggag ttccgtccgc acgttggcgc gggcgcgttc ctcgaagcgt tcgcgtgcgg
    12001 cgggcgtgtg gaagagccgg ggcagggcca ggaggccgtt gaggacttcg gcccgtccgg
    12061 cgcggaagaa ctcgtcgggg acgaacgcgt actcctcgcg gacggcggcc gcgtacgcgg
    12121 cgtaccgctc gggctccgcg ccgaggacgg cgaggtcggc gtcgcagagg acctgcccgt
    12181 cgcggtcgcc ctcctccggc gcgtgcgtgg cggtcagctc gacgagccgg accacgcgcg
    12241 cgacgaccgc gtccgggacg tcggtgtcgg cgagcatgcg cgcggccagg cgggcgctgc
    12301 gctcctcgtt gtcggcgcgc tcggggtcgt agacggcgtc gtggaaccag gcggcgatcc
    12361 ggacggcgtc cgggtcgtcg gcgtgcccgg ccagctcgtc cacgagatcg agcaccgcga
    12421 cgaggtgcgc gcgggtgtgg tagcggcggt gcgactcccc gtagcgccgg tcgagctcgg
    12481 tcccgatgtg ccgggtgtgg ggtcccgcca gcgccaccca ccggtcgaca agatccatgg
    12541 cgtccatcct ggcggatcgc gggacgggcc gggacacgcg gtgccatcgt tcttgcgtgc
    12601 ggagggcccc ccggccacta tggttgatca ctgcgagtta ggcaaggctt acctcactca
    12661 ctggaagggc cggtcgtggc cgcctctctc tacctggtcg ccggcaaggc gaccgactcg
    12721 gtgacgcacg gattcctgcc cgccgccgcg cgcctgggcc tcgacgtcac gctcctcacc
    12781 gaccgtccat ccgcccacga cgccggcgtg ccggtggtcg agtgcgacgt ctcggacttc
    12841 cgcgacatca tcgcgcgcgt cgaggacggc gccgcgtgcg gcgggggcga gcccgcggcc
    12901 gtcttctcca acagcgactt cctgcaggcg cccgccgcct tggccgccgc gtacttcggc
    12961 ctgcccgcga aggactggcg ggcggcgatc cgggcgaaga acaaggcgct catgcggcgg
    13021 cacctggcgt ccctcgaccc ggtcttctcg gcggacgcgg ggcgggtccc ggcgggcgcg
    13081 ccgtatccgc tcgtcctcaa gccgcgcgaa ggggtggcga gcgaggacgt gttcctcgtc
    13141 cacgacggcg gggaactggc cgcccgggtg gaggagatcc gggcccgccg cggcgatccg
    13201 ctcgtggccg aggagtacct gccgggccgt ctccacacgc tggagacgct gggggacgga
    13261 cgggaactgc gggtgctggg ctcgttccgc acgacgctct cgccgccgcc gttcttcgtc
    13321 gaggagcgcc ttgagtgggc gccccctccc ccggagacgg agcaggtcct gcggcagttg
    13381 gaggcgctgg gcgtcggttt cggggcgtgc cacaccgagt tcgtcgtcca cgaggggcgc
    13441 gcccgcgtca tcgaggtcaa ctaccggctg atcggcgacc actgcgacct cctgctggcc
    13501 gatctgctgg gcgtgcccct gttcgagcag atcctgcggg tccatctcgg ggcgtccctg
    13561 ccggaacggc gggtcccccg tcctcgccat gccgtggccg agccggtcat agccgaccgc
    13621 tgcggcacgc tcaccgcggc ccccggcccc gtgcaggtgg aggacggcgc ggttcggctg
    13681 gcgtaccgtc ctcagcgcgc ggtgggcgac acggtctccc tcacccggac caaccgcgac
    13741 tacctgggca ccgtgcgcgc catcggtcct ggaccggagg aagtgaacgc cgccctggcg
    13801 cggttccgcg cgacccacga ctggatgatc gcgtgacgga ccacgacgtc gaaggcccgc
    13861 tcgcggcccg cgttctggag gcgttgctga gggaggacta cgcgggccta aggcgccggg
    13921 tccggggccg cacgttggag cttccgggcc gttccgtgcg tcttgtggaa gcccggcccg
    13981 cctttctctc agagctcgtc gtggatcctg ggcagggcct gaggctgagc gacgtcttcc
    14041 atgccgtccg tctgatcgcc gacccggggg acgacacggc ttccttcgag cgcgagtgcc
    14101 ttgaggccct ggcggccatc cagctgcacg gtgaggcgcg tccggccgtc caccggcggc
    14161 tgggacgcct cccggccgag ctgcgggcgg gccccggcac gttctacgag acgctggcgg
    14221 cctacaacga ccaccctgtg caccccacgg gccggagccg ctccgggctg tccccggccg
    14281 agctgagccg ctacgcgccc gagttcgcgc cgtcgttccc gctgcgctgg gcggccgtgc
    14341 ggaacgcgac gcggaccggg tcgctccccg ggtggtggcc cgcgccgtcc gacgtgggcc
    14401 tgcgctcgga cgacgctgcc ggggcgctgt tccccgtcca cccgctggcg gctcggcagg
    14461 tcggcccccg gcccggcgtc tcgctcgcgc ccgatccgta cttgcaggtc acgcccactt
    14521 tgtcgatgcg gacggtcgcg gcggcgccgc tcgaccacgt gaagatgccg ctgccgacga
    14581 gcacgctcgg cgtccgcaac cggcgcacca tcgtgcccgg cacccttccg gacggcgcgc
    14641 tcgtcgaacg gatcctgcgc caggtccttt tacgggagcc gtcgcttccc gtccttctcg
    14701 ccgacgaaca gacctacggc cacgccgacg acccgcttct cggctatctg gtgcggcgct
    14761 tcccgcccga gaccgcccgc gcgcacatcg tccctgtggc ggccctgctc gccgaggcgc
    14821 cggaccgggg tcacgtcatc gagcgctggg acgtcgaagc gctcttcggc gcctacctga
    14881 cggcgctgct ttccttcaac gtcacgctgt tccggtacgg catcgcgcta gaggcgcatc
    14941 agcagaacgt ggcactcgtc ttggacgagt ctccggtccg cctcctcatc aaggacaacg
    15001 acggcgcgct gatcgacccg tcccgcctcc gggagcgcgt cccgccctct cctggcacgg
    15061 acccccgcga tctcgtcgac cgccggatga cgacgtccga tcccgaggcc ctcgcccgcg
    15121 tcttcgtcac catcaccctg catctctgcg ccgcggcgcc cgccctgggc ctggccgggc
    15181 ggggcctgct cccctggcgg accgggcgcc ggattctccg cgaacggctc gacggggcgc
    15241 tcgggccgga ggacgcgttc ctgcgcgccc gcacgctcga cgccgacacc ctgccgggca
    15301 aggccatggt caccgccggg accctcgtcg acaaggcgag gacaggcgcg gccgacatca
    15361 acaagcacta cggcccgccg gggcccaact acctactgga cacgacgtgc tgctgacaga
    15421 accggccgtc acggccgacg acgccaccgc gaccgcgctg ctcaactgcc tgatccggga
    15481 ggtctgcggg cccgagcagc aggtctggcc ggacggggcc cgcctcgtgt tccggctgcc
    15541 ccgcgcgggg gtcctgctgc gcgcgggtct ggcccgtccc ccggtcgggg cgacccgccg
    15601 cctggcgccg cccttcgagg agcgccgcga ggacgagtgg ataccggctc cgtgggacag
    15661 gctggcgaac ctggtcgcgg gtgaactgga gctggcgacc ggctccccga acgcggaatt
    15721 cctcgtccag gtcggagaca gccacgccgc gctcaccgcg atcctcgccg ccagaggaga
    15781 atccgctgag gaccactcca tcgactacat cgcctcagag cagtctcttg tcgcggggca
    15841 ccgtttccac ccgtctccca aggcccgcca gggttcgccg gaggagtggc tgccgtacgc
    15901 gcccgagacg agggcccggt tccgcccgct gtggctcgcc gtgcccgaag ggctcgtcgc
    15961 cgaggaaggg gcggctgagg cgttcaccac cttggaggcg tacggccctt cggtgccgcc
    16021 tggacgtcgg ttgctccccg tgcatccgtg gcagttctcc ttgctggcgg acaatcccgt
    16081 cttgcagagg gccctggcga ccgggtccct ggtcaatctc ggcccgtccg agatggaggc
    16141 ggtgcccacc tcgtccgtcc ggaccgcgta tctgccggac gccgatgtgt tctgcaagtt
    16201 cagcctcgat gtgcgcatca ccaactgcgt ccgcaagaac gcctggtacg aactgaccgg
    16261 ggcgatgacg ctcgacgagt tgctgccgcc catcctggag aagctgaacg ccacgttcct
    16321 cagagaaccc gcctaccgca gcgtcgccct ccctgaccgc agcctgtacg agggcctggg
    16381 agtgatcctg cggcagggca tcagatccct tcccggcacg cctcttctgg cgggcgccct
    16441 ggccgacccc tacaacgcgc tcctctccgg cctgcccgcc ctctcctccc cggacagcgc
    16501 ccaagcctgg tgggacgcat acgtggccca ggtggcaccg cccgtgctgg gcgcctatct
    16561 ggaccacggc gtcgtcctgg aacctcatct gcagaacgtc ctcgtctgcg tcgacacgga
    16621 cggcatgccc gtccatgccg ttttccgcga catggagggc accaaactga ccgcggggca
    16681 ctgggacctg tcgcacctcc ccggccgcgt ggccgagggc ctcacctatg cccccgacag
    16741 gggctggaac cgtgccgtct actgcctcct cgtcaaccac ctcaccgaga tagccgccgc
    16801 cgtcgccgac ctccacccgt ccttggacga gaccctctgg caggcggcgc gcaagcattt
    16861 cgccgccttt gaccgccacc cgcaggtcag agctctcctg gccggtgtgc cactgcccgc
    16921 caaggcgaat ctccgcaccc gctggtcacg gacggccgac cgcggcgcgg cctacgtccc
    16981 cgttcccaac ccgctcgccg cccgaccgct gtgaacgagt tcgcgctgaa cctcgaccgc
    17041 tacccggcct atgtgtacga cctgcccgga ctcgaatccc acgtccgcgg catacgcgcc
    17101 gcgcttcccg gcacagaggt cctgtacgcc gccaaggcca atccggacgc cgagatcctc
    17161 cggactctcg cgccccacgt cgacggcgtg gaggtgtcgt ccggcggcga actcgcccac
    17221 gtccgggaga ccctccccgg caagcctgtg gcttttggcg ggcccgggaa aacggctgac
    17281 gaactggcct tgtcccgcac gctcaaggcc gaccggatcc atgtggagag cccgaacgag
    17341 ctggctcgcc tggccgccct gggccccgcg gacgtcctgc tccgcgcgaa tctgcccgtg
    17401 aacgtgccga acgcggccct caccatgagc ggccctttcg gcatggacga ggacaccctc
    17461 gaccattgcg cccgcctttt ggccgagtat ccgaacatca cccttcgagg cgtccacgcc
    17521 cacctggcct ccggcctgga cgcgcccgcc atgctcgacc tggcccaccg gacggcggaa
    17581 tgggcgattc cctggctccg ctcccgagga gtggacgacc ctgagttgaa cgtgggcgga
    17641 ggcatggcgg tggactacac gtcccccgag tcccgcttcg actggcagac ctacgggacg
    17701 ggcctcagcc atatcccagc gaaagtccgc atagaaccgg gacgggcgat gaccgcgtac
    17761 cacggctggt acgtcaccga cgtcctggac gtgaagacca cgcgcggcga gacctacgcc
    17821 gttctcagag gcggcaccca ccatctgagg acccccgtga cgaagggcca cgaccagcct
    17881 ttcgaggtgc tcaccgcgaa cggcccggag cgccgggcca ccctggtggg ccagctctgc
    17941 acgccgaagg acgtcttcgc gcgcgacgtc ctcgtcccgc cactggcgcc gggcgacgtc
    18001 atcgccttcg ccatggccgg ggcctacgcc tggaacatct cccaccacga cttcctgatg
    18061 cacccgaaac cggccttcca ctaccggcgc cgaccggacg ccggagggtc agccgcgagg
    18121 gctcccgtac cagcgccatg acgtgacgcg cgggtgtccg ggaaggtccc cgcgaccggt
    18181 ggcccacagc agggtcggcc aggggtcggt gtcctgcggc gcgccgggga acaggcgccc
    18241 cagcacgcgt gcgcacacgt cggcgggcgg ctcccaggac agccccagcc cctccgccag
    18301 gtcgtgcatg tggacgaggg tctcgacgat gcccatcgcg gcgaacccct cggcgtccga
    18361 agcgccgaag acatggtgcg cgcggacgtc cggggccgtg cggcggacca cggcggacag
    18421 catcccgccg cacgcgtcga gtacctgcaa cagccccgcg ggcccggcgc tcctgtccgc
    18481 gtggacggcg ttggccggtc cgccggaccg ccggctctcc cagacgaacg gcacctcgcc
    18541 gtccatcggc ggcgtcctcg gcgcaagctg ggcggcgtag gcgaacaggt cgtcgctgag
    18601 atgctcgacg gtctcccagc agtcccattc gagcgacccg gccttcccgt cccaagcctc
    18661 ggggggagcc tcccgcaggg cggcgacggc cagccgaacg gcgaggtcga gatcgtctgc
    18721 ggtcacggcg gcggtcgaat gcggcatggc cccgaccgta ctggacgtcc ccgggccgcc
    18781 cgtcagccca tcggcgcggc ggtcccgctc acgccgatgc ccgtgtcccc cggggggacg
    18841 tccacgagca gccggctggg gcggcccatg tcctcaccct ggtggacggt gatccgggcc
    18901 ggaggggcga cgaggcccag cgagcgcagg tacccgccga aggccgccgc ggcggcgccg
    18961 gtcgccgggt cctccacgac cccgcccggc gggaaggggt cgcgggcgtg gaagacggtc
    19021 gcgctctccc gccagacgag gtggacggtc gtccagccgc ggcgcgccat gagcccgccg
    19081 agggcgtccc cgtcgtagtc gaggccggcg agccgggcgc gcgtggacgc cgccagcacc
    19141 aggtggtcgt tgcccgcgtt ggcgatgcgc ggcggcagct ccgggtcgag ctccccggcc
    19201 tcccagcgca gcgcgtccag ggccgcggcg aggtcggcct cctcgacggc ccggacggtg
    19261 ggcgggacgc tggtcagggt ggcgaggacg cggccgtccg cctcccgggt ctcgaccccg
    19321 acctcgccgg ccggggtgct cagccgcagg ctccccgtcc cccgccgctc ggccagcgcg
    19381 acggcggtcg cgatcgtggc gtgcccgcag aaggcgacct cggccagcgg gctgaagtag
    19441 cggatcgcga accgcccggg cgcgcctccc tcgtccacga ggaaggccgt ctcggagaac
    19501 ccgatctcgg cagcgatctc ctgcatgcgc gcggcctcca ggccccgggc gtccaggacg
    19561 accccggccg ggttgccgcc ctccccgtcc acgtcgaagg cggtgtagcg gagtgctggt
    19621 gcgatgtcgc tcatgcgagc agtctgctcc agccgctagc atcgcgtcca acgatgaata
    19681 ttgatcagag gcatcgggat attcgatgga cacgcgcctc ctcaccacct tcctcgcggt
    19741 cctgcgcaac ggcgggatga ccgccgccgc ggcggagctc ggcttcgtgc agtccaccgt
    19801 caccgcgcac gtccaggcgc tggagcgcct cgccgggacg ccgctgctcg accgcctccc
    19861 cgggggcgtc tcccccaccc gtgccggttc cctgctcgcc gagcacgccc ggggcgtcct
    19921 cgatctccag gagcggatgc tcgcggaggt caccgccgcc gccaccgagc cgtccggccc
    19981 ggtgcggctc cgggccccgg agtccgtgtg cgcctactgg ctcgcgcccc tgctgccccg
    20041 gttgcgggcg cgactcccgg acgtgaccgt ctcgctgttc cccgccgaca cccggaccgc
    20101 gctcaccgcg ctcgccgacc gcggcgccga cgtggccctc atcctcgacc cctcgccgga
    20161 cccgtccggc gtggacctgg tcgacctcgg cgcccaaccc ctgtcactcg tcgcggcggt
    20221 gtccacaccc ctccccagga accgtcccct caccccggcg gagctggccg cgaccggcat
    20281 cgtccttctg gaggaaggct gctcctacag cgacgagttc gccgccctgg tcacggccgc
    20341 ccgtcccacg gcgaacccgc cccgcttcgg aggcatcgag accgcgaagc gctgcgtggc
    20401 ggcgggcctc ggcgcggcgc tgctgcccac ggtcacggtc gccgacgaac tggccgccgg
    20461 cgcgctcgcc gaactgaccc cgcccgccgg cctgtcccgg caccacctct ggctcgccga
    20521 gccggcctcc cgctggcgct cccccgccgt ccacgccctc cgcaccgccc tgatcgactc
    20581 gatcaccggg ccgggcgccc ccggttcgcc gccgcgcccc tgacgttccg acttcgcgcg
    20641 ctcgtagtgc cgggcggctt tgacccggtt tccgcagacg gccatggccg ccgcggcgcc
    20701 gggcgccgaa cggctggtcg agttcaccgt caccggcgtc gtcgagaccg ccggggcgtc
    20761 accactgcgg tggagcgacc ccgtcccgtc ccgcgtcaac ccgcccgcgg ccttgaatct
    20821 cccctgaggg gagatgccag ggtggggccc atggacggtg aagcgaccta ctccatcggc
    20881 gaactcgccc ggagcgccgg ggtcaccgtg aaggccgtgc ggttctacac cgagcgcggg
    20941 atcgtcccgg cgcgcaggac cgcggcgggc caccggcggt acggagccga cgccgtggcc
    21001 cggctgggcc tggtgcggac gctgcgcgag ctggggatcg acctggccac cgtccagaag
    21061 atcgtcgacc gcgaggtgcg ggccgccgac gcggccgccg cccacgccga ggccgtcgcc
    21121 gcccagatgc ggatgctgcg gctgcggcac gcggtgctga ccatcgccgc ccgccgcggc
    21181 agcgatcccg aggagatgga actgatgcac cggctcgccc gcctgtccgc cgccgaacgc
    21241 gacgacctcg tcgccgactt cctcgacagc tccttcggca cccccgacgc ggggccgatg
    21301 tcccgcgtcc tgcaccggtc gctggccccg gaactgcccg acgaccccac gtccgagcaa
    21361 ctggccgcct gggtggaact ggccgagctc acgcgcgatc ccggcttccg tgccctgatg
    21421 cggggcctgt tcgacgacca cgccaccgag gccgcccggc gcacgggccc accacgcaag
    21481 cacgccgtgg cgcgggtcgc cgagaccgtg cgccccctgc tcgccgcagg agcagccccc
    21541 gactcacccc gggcggccca agccgtcacc gacgtggtcg ccgcctacgc cgagttccag
    21601 ggccgacccg acacccccgc cctgcgcgcc cgcctggcca cctacctgac cagcgccaac
    21661 gacccacggc gggagcgcta cctgcatctc ctgtcgaccg tcaacgactg gtccccgccc
    21721 gaccaccccc gccacgaact cgactggttc ctggcagccc tcaccagttc ctgacaacgg
    21781 ctcggcacac ccgtcgctgc ccgtcgcttg gcggcgcctt tgctcggccg aaagccgggt
    21841 atgccggacg gcgggacgag gagttcgggg cggcggagga gtgtcttgct ggtgcttgag
    21901 cgggtgcgtg gtgctgcgga ggcgggagtc agggcggccc gggcggtgcg ggacgccggg
    21961 gtggtgcggc ccgtccggcc tgatcgggcg gcgcggcttc tgtttccgta cgtgcggttc
    22021 gggcccgtcc ccgcgacgct cggcgccatg gccgcgctgc ggttccccga ccggacggcc
    22081 ctgatcgacg agcgcggcgc gctgtcctac gcggaactcg aacggcgggc ggcggcgctg
    22141 gccacggcgc tcagcggccg tgtgggcgac gggaaggtcg ggatcctgtg ccgcaatcac
    22201 cgggggttcg tcgaaacggt cctcgcggcg acgcggctgg gcaatgacgt cgtgctgctg
    22261 aacaccgatt tctccgggcg gcaactgggg caggtcgtcg aacgcgagga gatcgaactg
    22321 ctcgtgcacg acgaggagtt cgggccggcc gtcgaggagt cggggttcgc cgggaagcgg
    22381 gtggtcgcgt gggccgacgg cggcggggcg atcgacgcgc tgatcgagga gaccgctccc
    22441 gaacccgtca agcccgagcg ggccagccgg gtgatcctga tgacgtccgg gacgaccggc
    22501 acgcccaagg gggcacggca cgatctgtcc gcctcgtcgc tgctgcccgc ggccctgagc
    22561 catctgatgc gcgttcccgt ccggtcgggc gcgccgatgg tcatcgggcc cccgctcttc
    22621 catctgctcg gcttcgccta cacgacggtc gggctcgcca tggggatgcc gctcgtgctg
    22681 tcccgccgct tcgatccccg gcaggtgctg gagacgatcg cggacagccg ggcggaggcg
    22741 ctcgtggcgg tgccggtgat gctccagcgc gtcctggacg tgcgggacgc gccgccgacg
    22801 ccggcgctgc gggcggtcgt gtgcggcggg gcggccctgc atccgcacct gtccgaggcg
    22861 ttcatggacg cgttcggcga cgtgctcgtc aacgtctacg gcgcgaccga gaccgggtgg
    22921 gccacgatcg ccacgcccga ggacctgcgg gccgcgcccg gcacggtcgg caggccgtcc
    22981 ttccggctca cgatcaaggt gctcggggag gacgggcggg agctgcccgc gggcgagacc
    23041 ggggaggtct acacgggcgg cggcctgcgg ttcgccgggt acaccggggg cggcggcagg
    23101 cgcgtacggg acggcctgac cggcaccggc gacctcgggc acttcgacgc ggcgggacgg
    23161 ctgttcatcg acggccgcgc cgacgacatg atcgtctcgg gcggggagaa cgtgttcccc
    23221 ggcgaggtgg agaacctgct cggcggccac ccggacgtcg cggaggtgtc ggtcaccggg
    23281 gtggacgacg agaggttcgg gcagcggctc gccgcgcacg tcgtcaggac cgagggggcg
    23341 gaggtcgccg aggacgacct cagggagtac gtgcgcgccc acctggcccg gtacaaggtc
    23401 ccgcgggaca tccggttcgt ccgggaactg ccccgcacca gcaccggcaa ggtcaagcga
    23461 cggcccgacg gcggtcgatg agggaaacgc ccgggcccag ggccgcgagg tcccgggcgt
    23521 gccccgtccc gagggtcagg cggcgccggc gcgccgcttg gcggccatgc agatgcgggc
    23581 gaggtcgttg agggcgtcgg cgcggcgctc gtccagcgtc cggtggtcgc ccggcccggc
    23641 ctccgcgagc gtgtcgatga ccagggagaa caccggccat tcggcgggcc cgatggcgcc
    23701 ctggaagtcg acgccgtccg ccaggtcgtc caggtcgagg ttgcgggcga aggtggcgag
    23761 ggcggcctcg gccgcgacca cgccgatgcg catcgccagc gcggccggct cgcgatcaag
    23821 ggcgcgcacg gtgctggaac ccatgttcga caacatagac cacacgcgtc acacgcgtcg
    23881 aacgtttgct cgaaaccgtt atccgacgat ggcctgctgg aagaggtagg agtgcgtgaa
    23941 gtgcagggcg ccgtcgacca tgctcgggcg catgccggtg gcgggtccgc ccgccagctc
    24001 ctcctccagc tcccgcctga tctgcgccgc ggcgtccgag ggggtgtgcg agaactccag
    24061 ccacgggtcc agcgggcggc tgtggtcgaa ccggtcggcg cgcttgaccg ccgcgcccgc
    24121 cgccgtgacg agctccgcga tccgcgcctc ggtgagagcc gccccgtgcg aggggtcgcg
    24181 gaggcgctcg atccggtcgg gatcgccgtc cagtccctcg ggccggacca ggtcggcgat
    24241 gatcagcgcg gcgccggggc ggctgacccg ggccatctcc gtcacgacgg ccccggggtc
    24301 ggcgacctgg tgcagcgaga agcgggtgac gacgagggtg aacgaccggt cgaggtaggg
    24361 cagggccgtg gcgtcgccgt gcgcgaaggt gacgttggtg aggccggcgt ggtcggcgtc
    24421 gcgcttgccc tcggcgagca tcgcgggcgt gaggtcgagc gccgtcacgt gccggacgcg
    24481 gcgggcgatc gcgcgggaca cgatgccggt cccggcggcg acctccagaa cgacgtcctc
    24541 caggtcgagc tcggggtcca tgaaccggac gagccggtcc agatggcggg tgaaggccgt
    24601 gttcagcctc gggtcggaga acccggccgc ctgcttggag aactcccgta ccaccttctc
    24661 gtcatgggac accgacacgc cgcctcctcg gatggttgcc cggatcatcc ccgaaaccac
    24721 gcatggtgaa cagggggcgg cgacgaaacc ctcaggcggc ggggacgccg tccagcagcg
    24781 cggcgagccc ggccgcgtcg agcaggtcgg cgggacggac ggtgacctcg gcggagacgt
    24841 agtggaacgc ggcgctgacc cgcgcgacgt ccacccccgc gagttcggcc cacgccagcc
    24901 ggtacgcggc gagctgcacg gcggagaacc gggcctcgtc cccgcgcggc ggggcgccgg
    24961 tcttccagtc gacgacctcg tagccgccgt cccgggaccg gaacaccgcg tccatccggc
    25021 cccggaccag ccggtcgccg atgatggtct cgaagggcac ctcgatgtcg agcggctcgc
    25081 gcgccgccca ctccgaccgc tcgaagcgct cgcgcagcgt cgccaggtgc gcgtcgtcgg
    25141 cggcgccctc gtcggcggcg ccgggcagct cgtcggggtc caggaggcgc tgctgccccc
    25201 agcggccctc cagccaggtg tggaaggcgg tgccgcgccg cgcgtagggg gcgggcgggc
    25261 gcggcatggg acggcggatc tgccgcgcga gcgccgccgg gtcgcgcgcc agcgacacca
    25321 gcgacgacac cgacaggtgc gcgggcagct cgacgagcag gccgtcgccc ccgcgccccc
    25381 ggtcgcgctc ggcgagcagc agctcgacgt cgcgcgccca cgccgtcatg cgcccccggt
    25441 cggcgtcgga caggccggtg tccccggccc agtggcgggt gcgcccggcc atctcgtcct
    25501 cgaccatgcg ggccccctcc acgaccgcct cgtagcgcgc ccgcgccgac aggtcggacc
    25561 ggccgcgctc gcccggcgcg atgggccact gcgcctcctc ggggtcggcg agcagcgggt
    25621 tggcggcgcc ctcctccggc gggtcggccc acaccgcgac ggacccggcc ccggcgaggc
    25681 agaccgcccg cacctcctcc aggaacggcg acgggccgag cgggcggccc gaggaccccc
    25741 accagtagcc ggtggtgatc agcaggctgg acgcgcgggt gaccgcgacg taggcgagcc
    25801 gccgctcctc ccgcaggtcg cgctcggagc acgcctggtc gaaaacggag aggtcgtcct
    25861 tctccagccc ggtcagcgcg ggcaggtcgg cgcggtcgcc gcgcagcatg aacggcagga
    25921 cgcgcgggtt cgccgtccag cgggtggcgt tctgcggcgg cgaagggaag atcgacccct
    25981 tggcgggtga accgttcttc tgcggcgtgt acgccaggcc ggggacgacg acgaccggcc
    26041 attccaggcc cttggaggcg tggacggtga ggagcttgac gctgtcggtc tccccgaccc
    26101 gtccggcctc caggccgaac tcctcggtct cggcggcctt gaggtaggcg aggaacgcgc
    26161 cgagcgtcgg gtcctcggcg tcgcccgcga acgtggcggc ggcgtcgatg aacgcgtcga
    26221 ggtcggcgcg ggcggtgacg gggtcgagcc cggaccgcgc cgcgacctcg atgtcgaggc
    26281 cgagcgcgcg ctcgacctcg ttggccaggt cgggcagcgg cagcccgacc tggccgcgca
    26341 gggcgcgcaa ctcgtcgcgg aggcggcgca ggcgcccgta cccctcgggc gagaacgcgt
    26401 cgggcgggcc gaggtcgtcg agcgcgtcga cgaggctgcc ggtctcctgg ttcagctcgc
    26461 tgacgagctg ccgcagcgga tcgtccccgc cgtcaccctc gccggccccc tcaacggagg
    26521 cgacgccgaa ggcggcgtcg gacgcgtcgt cggccccttc gcggggcgct gcgccggact
    26581 cgtcgccgga ggtggcgccc gacgcggggc cgggcgcggc ggcggaggcg gggtcgggct
    26641 cggcggtcga cacgctgccg agaacgctgc ctgacgcggg gccgaggccc tcgccggggg
    26701 cggcggggcc gggcccctcc tcgggcgcgg cggcggggac ggggtcgggg cgggtgatgt
    26761 cgcgggccga ttcctgggcc agggcgcggg cgcggcggcc gagggcgacg aggtcgcggg
    26821 ggccgaggcg ccagcgcggc ccggtgagca gccgggcgag ggacgcgccg gcggtcgggt
    26881 cgtgcatgac gcgcaacgtg gcgacgacgt cctgtacctc ggggacggtg aggagcccgc
    26941 cgagcccgac cacctcgacc gggatgccgc gcgcctccag ggcccgcctg atcagcggga
    27001 actgcgaccg cttccgggcc aggacggcga cgtcggagta gcggagcggt tcggcctggg
    27061 ggccgccgtc cggggcggtc tcggggtcgc cggccatgag cccggcgatg cgcgcggcga
    27121 cgcggtcggc ctcgtcctcc acggtgggga agagggcgca ttcgacgcgt ccgcgcccct
    27181 cgcgtccggc gcccgggatg aggcggggca cggacctcgt ctcggcgcgc agctcctcct
    27241 gcaccctggc cgccgcctcc aggatctgct cgccgttgcg gaacgaccgg ctgagctgca
    27301 cgaccggcgc cgccacggga cgccccccgg gggccgccgc cggctgcaga gggaagtcgt
    27361 gggcgaaccg cagcaggttc ccggcgctcg cgccgcgcca cccgtagatg gactggcagg
    27421 ggtcgcctac ggccgtgacg gggtgcccgc ccgcgaacag cgacgtcagc aggacgagct
    27481 gcgcctggct ggtgtcctgg tactcgtcca gcaggacgac cgagaaccgg gaccgctcga
    27541 tcatcccgac ctcggggtgc ttgtaggcga tgcgggcggc gagggccatc tggtcgccgt
    27601 ggtcgatgac ctcgcggtcg gccttggcgc gcccgtacgc ctcgatgagc ggcatgagct
    27661 gctcgcggac ggcgtgcttg gcgaggatgt cgcgctgcgc cttgagcggc ttcttcacca
    27721 cggcgagccg ctcgtcgagc caggcgccga ccctgcggac gtcctcggcc gtgcgcagat
    27781 gctccgacag gtcgccggac agttccatga cggccttggt gacggtgtcg ggctgccagt
    27841 cgatccggtc catggggccg tggtaggcgt cgaccacccg cgagcagatc tgccaggcga
    27901 cggccggcga gatcagccgc atcgtgggtt cgagcgcctc gcgcagggcg tggtcgccga
    27961 agagccgcgc cgcgtacgag tggtacgtgg acaccatcgg ctcgccgtcg aacagggcct
    28021 cgccgcccag ccgttcgagc tcgtcgcccg gcaggacctc gcggagcctg tcgagccgct
    28081 tgcgcacgcg cacgccgagc tcggcggcgg ccttgcgggt gaaggtgagc ccgaggacgc
    28141 gctccggccg gacgaagccg ttcgcgacca gccacaccac ccgcgcggcc atcgtctcgc
    28201 tcttgcccga cccggcgccg gcgatcaccg ccatcggcgc catcggcgcc tcgatcaccc
    28261 gggcctgctc ctccgtcggc gccgggatct ccagcagccg ggccagctct cccggcgtga
    28321 tcacctcgct ccccccgagc cagtcagtcg ctcacctgcc cgccctcgtc atggacgggg
    28381 cagcaggagc gtacgggaca ggtgcgacac ttgtcgttcg ccctggcctg gaagacgtcg
    28441 ccggccatcc ccgtggcgac gatctcgacg agccgcttcg gccactcggg gtcggcgtcc
    28501 tcggcgggcg ggggctgctc ctgctcacgc gccttcgccg tgaacgcggc cttgccgacc
    28561 tggatcagct tcgcgccgcc cggctcgatc agcccgtgcc gctcgaacgc gccgagcatc
    28621 accgcgtact ggtacacgcc gagctgcggg tgccgggcca ggtcgtcctt cgggacggcg
    28681 gtcgaggagg tcttgatgtc gatgatgacg gcccggccct gctcgtcgcg ctcggcgcgg
    28741 tcgatgcggc ccttgatgac gacgcggccg aggtcgacct tgaacgactc ctccagcgcg
    28801 acgacctcgt tggggttgtc gcggtgccag gcgaggaact tgtcgaccat cttcgcggcc
    28861 tgctcgcgct gcttctccga gtaccacgag ctgcggaact ccaggtcctt ccagatctcg
    28921 tcgagccgct gcgcgacgtg cacctcgtcg acgccgtcgt ccgcgcccgc catctcggcg
    28981 acggcgtgga ccaccttgcc catcgtgctg tactcgttgg gcccgccctc ctgggcgccg
    29041 accgccgagg cgagcagcca gcgcagcccg cacgtggtga acgcctcgac ctgggacggt
    29101 gagatcgtga tgggctcgtc ctcggcgaac gcgggcccgc cgtcggacag ggcggtgatc
    29161 gcgtaccagt tctccggcct cgcgccgcgc acgcccgcgc gcgccaggcg ggccaggtgc
    29221 ccggccgccg cgcgccgcag cggttccggg cgggacgggt cgccgacgac ggaacgcagg
    29281 tcggccacca gcgccgacag cgacagccag cgggtcttct cgtccagctg ggactgctcg
    29341 atcgcgccgg ggagcagctc gttcaggaag cgggacggcc tctcctcggt gtcgtcgccg
    29401 ccgacggccg tcaccacgag ccgtctgcgg gcgcgcgtga ccgccacgta gaacagccgc
    29461 cgctcctcgt cgagcatctt ggcggccatc gaggcgccgg cggcggcgtc cccgtcgggc
    29521 tcggccccgg ccgcgtgctc gaccagctcc tcgacgccga gcagcgaccc gcgcagccgg
    29581 acgtcgggcc agacgccctc ctggacgccg gcgacgacga ccacgtccca ctccaggccc
    29641 ttggagcggt gcgcggtgag gatccggacc gcctcgccct cgggcgcctg ctcggccagc
    29701 gtgtcaccgg cgatctcctg ggacgcgacg ttgtcaacga acagctcggg ccccgcctgg
    29761 gggagccggt ccacgaaccg cgcggcgtgg tcgaacagcg ccaccacggc gtcgaggtcg
    29821 cggtcggccg ccgcgccgcg cgtcccgccc ttgacgctct gctccagcag cacgtcggcc
    29881 tggccgctct cctgccacac ggcccacagc acgtcctcgg cggtgccgcc gtcgtgcacg
    29941 ctgcgccgcg ccacctcgat caggttggcg atccgctccg ccggcgcccg gaccctctcg
    30001 tggaccagga ccagctcccg ggggtcgttc accgccgcga ccaggagatc gcccagctcg
    30061 cgctgcccgc ccgacagctc ctccaggtcg cgcagagcgc gcttgagccg gcgcatggcg
    30121 agcgcgtcgg cgccgcccag cgggccggtc aggaggtctt cggccacgac ctcgtccagg
    30181 aagcccttct tcagcgccgc ccgcagcagg acgaggaacg ggcggacggc gggctccccc
    30241 accagcggca cctcgtcacc ggcgaccacc accggcacac cggcctgggc gagcgcccgc
    30301 cgcagcaccg ggacctgccg gacggcgctg cgcaccagga ccgccatacg cgaccacggc
    30361 acgccgtcga gcaggtgggc gcggcgcagt tcgtcggcca ccagcgcgga ctcctggctc
    30421 tcggagtcgg cgatgaccgc gcgcacctcg ccctcgtcga gctcctccac cggccgcagc
    30481 gcgcggtgct cggccgcgcc cgccgccccg gcgggcagcc gccgcgcgat gcggcgcgag
    30541 gcggtgagga tctcgggtcc catccggcgg cacgtccgca gcgccaccac gggcgccggg
    30601 gcgccgtcca gggcggggaa gcggtccggg aactcctgga tgccgcgcac gtccgcgccc
    30661 cggaacccgt agatcgactg gtccggatcg ccgaccacga ccaggtcgcg cccctcgccc
    30721 gcgagatggt gcaggagggc ctcctgcgcg gggtcggtgt cctggtactc gtccacgaac
    30781 acggcgtcgt aggcgtcgcg ctcccggatc cgcacctcct cgtccgcgag catccccgcg
    30841 gccaggtgga tcagctcgcc gtagtcgtag gtggggacgg ggtcgagcag gaaccggtcc
    30901 acgtaccgct ccatgaaccc gccgatggcg gcccagtcgt cgcggcccct catgcgtccg
    30961 agagcggcga ggtcctccgc ggcgtactgc cgctcgaccg cgcgcagggc gaag
//
