LOCUS       NZ_BMRD01000007        32918 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Actinomadura citrea strain JCM 3295 sequence07, whole genome shotgun
            sequence.
ACCESSION   NZ_BMRD01000007
VERSION     NZ_BMRD01000007.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Actinomadura citrea
  ORGANISM  Actinomadura citrea
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 405946)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: BGI assembly pipeline
            Genome Coverage                   :: 127X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014648455.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 03:26:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,339
            CDSs (total)                      :: 8,265
            Genes (coding)                    :: 8,175
            CDSs (with protein)               :: 8,175
            Genes (RNA)                       :: 74
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 90
            CDSs (without protein)            :: 90
            Pseudo Genes (ambiguous residues) :: 0 of 90
            Pseudo Genes (frameshifted)       :: 12 of 90
            Pseudo Genes (incomplete)         :: 83 of 90
            Pseudo Genes (internal stop)      :: 3 of 90
            Pseudo Genes (multiple problems)  :: 8 of 90
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:33:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 32918
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMRD01000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..32918
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..32918
                     /SMILES="NC(CCC(=O)N)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..32918
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<0:12918](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<1..12918)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     CDS_motif       complement(<1..77)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS18700_0005"
                     /evalue="1.10E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="IEZ14_RS18700"
                     /protein_end="846"
                     /protein_start="820"
                     /score="43.3"
                     /tool="antismash"
                     /translation="PPGVVGELFVGGAGLARGYLGRPGLT"
     aSDomain        complement(<1..1124)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS18700_AMP-binding.1"
                     /evalue="4.90E-95"
                     /label="IEZ14_RS18700_AMP-binding.1"
                     /locus_tag="IEZ14_RS18700"
                     /protein_end="846"
                     /protein_start="471"
                     /score="310.4"
                     /specificity="substrate consensus: Thr"
                     /tool="antismash"
                     /translation="VEEQAARRPEGVAVVCGTQRLTYGELERRANRLAHHLRALGAGPE
                     VRVGVCLPRSIELVIALLAVVKSGGAYVPVDPDHPGERIAYVLDDAGVRILVTSGRAGE
                     RAPAGTDLPTVRMDEDAAAIDRWPAEAPPPNTVPGSLLYVIYTSGSTGRPKGVMVTHAA
                     LVRLLTATRPWFSFGPDDIWTLFHTVTFDFAAWELWGALVSGGRAVVVPTAVTRSPEKF
                     RALLVRERVTVLNQTPGAFRNLMAAEDADATEGWPALRVVVFGGEALMPGMLTGWFARN
                     GDQAPRLVNMYGITETTVHATYYPLSAADVPAADFAEAPDSPSSERSPIGVPLPDLSAY
                     VLDGELHPVPPGVVGELFVGGAGLARGYLGRPGLT"
     aSModule        complement(<1..2480)
                     /domains="nrpspksdomains_IEZ14_RS18700_Interface.1"
                     /domains="nrpspksdomains_IEZ14_RS18700_AMP-binding.1"
                     /incomplete
                     /locus_tags="IEZ14_RS18700"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     gene            complement(<1..2537)
                     /locus_tag="IEZ14_RS18700"
     CDS             complement(<1..2537)
                     /NRPS_PKS="Domain: Interface (19-441). E-value: 5.6e-56.
                     Score: 182.2. Matches aSDomain:
                     nrpspksdomains_IEZ14_RS18700_Interface.1"
                     /NRPS_PKS="Domain: AMP-binding (471-846). E-value: 4.9e-95.
                     Score: 310.4. Matches aSDomain:
                     nrpspksdomains_IEZ14_RS18700_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.5"
                     /locus_tag="IEZ14_RS18700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_189269932.1"
                     /sec_met_domain="Condensation (E-value: 7.2e-23, bitscore:
                     75.5, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.2e-91, bitscore:
                     301.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDDGEFETGFPRDHRAAAIPLTPAQRRLWRLQGGPGVGPYATTCT
                     VHLTGGLDVDRLAAAAEAVAARRTESRLVFSPHDDSAAARTGPVQTVAARPRITFRRLD
                     LMCPDRAEGAAEPAEHAAEVEHRTPLTEGVELNVLAVRLAEGRHAVTFSLPAICADVTT
                     MRSLAHEVVERAAGRTPRAGGLPYDGVAAWWNEMAELPEGATAREFWRSRCAGWDQPIE
                     LPGQRKHRAGPFRPQALTGFLPPAETMALRRRCPSPNDARGWLLACWQVLLRRMTGAGA
                     LVVGVATDLRRHEELRGCSGPLTVTLPVRLDRPLDVAVSAAAAETAEQIEAGDAHAEWY
                     SWERCVPPAAPGRPSWFPIGFDFDAGQRPADHDGAGPTESYGHHDRFLVRLSCQDTGER
                     MRFTLGYDGDALPRSAAGQLMDSFLALVADSLDRPDSACRDLDLLGPEGRRLLLRSGGD
                     PESEPSGACLAALVEEQAARRPEGVAVVCGTQRLTYGELERRANRLAHHLRALGAGPEV
                     RVGVCLPRSIELVIALLAVVKSGGAYVPVDPDHPGERIAYVLDDAGVRILVTSGRAGER
                     APAGTDLPTVRMDEDAAAIDRWPAEAPPPNTVPGSLLYVIYTSGSTGRPKGVMVTHAAL
                     VRLLTATRPWFSFGPDDIWTLFHTVTFDFAAWELWGALVSGGRAVVVPTAVTRSPEKFR
                     ALLVRERVTVLNQTPGAFRNLMAAEDADATEGWPALRVVVFGGEALMPGMLTGWFARNG
                     DQAPRLVNMYGITETTVHATYYPLSAADVPAADFAEAPDSPSSERSPIGVPLPDLSAYV
                     LDGELHPVPPGVVGELFVGGAGLARGYLGRPGLT"
     CDS_motif       complement(642..698)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS18700_0004"
                     /evalue="4.20E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="IEZ14_RS18700"
                     /protein_end="632"
                     /protein_start="613"
                     /score="34.5"
                     /tool="antismash"
                     /translation="YVIYTSGSTGRPKGVMVTH"
     CDS_motif       complement(897..938)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS18700_0003"
                     /evalue="6.20E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="IEZ14_RS18700"
                     /protein_end="547"
                     /protein_start="533"
                     /score="16.2"
                     /tool="antismash"
                     /translation="LAVVKSGGAYVPVD"
     aSDomain        complement(1215..2480)
                     /aSDomain="Interface"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS18700_Interface.1"
                     /evalue="5.60E-56"
                     /label="IEZ14_RS18700_Interface.1"
                     /locus_tag="IEZ14_RS18700"
                     /protein_end="441"
                     /protein_start="19"
                     /score="182.2"
                     /tool="antismash"
                     /translation="PLTPAQRRLWRLQGGPGVGPYATTCTVHLTGGLDVDRLAAAAEAV
                     AARRTESRLVFSPHDDSAAARTGPVQTVAARPRITFRRLDLMCPDRAEGAAEPAEHAAE
                     VEHRTPLTEGVELNVLAVRLAEGRHAVTFSLPAICADVTTMRSLAHEVVERAAGRTPRA
                     GGLPYDGVAAWWNEMAELPEGATAREFWRSRCAGWDQPIELPGQRKHRAGPFRPQALTG
                     FLPPAETMALRRRCPSPNDARGWLLACWQVLLRRMTGAGALVVGVATDLRRHEELRGCS
                     GPLTVTLPVRLDRPLDVAVSAAAAETAEQIEAGDAHAEWYSWERCVPPAAPGRPSWFPI
                     GFDFDAGQRPADHDGAGPTESYGHHDRFLVRLSCQDTGERMRFTLGYDGDALPRSAAGQ
                     LMDSFLALVADSLDRPDSACRDL"
     CDS_motif       complement(1581..1739)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS18700_0002"
                     /evalue="2.10E+00"
                     /label="C2_DCL_024-062"
                     /locus_tag="IEZ14_RS18700"
                     /protein_end="319"
                     /protein_start="266"
                     /score="0.8"
                     /tool="antismash"
                     /translation="ACWQVLLRRMTGAGALVVGVATDLRRHEELRGCSGPLTVTLPVRL
                     DRPLDVAV"
     CDS_motif       complement(2337..2420)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS18700_0001"
                     /evalue="1.80E-05"
                     /label="C2_DCL_024-062"
                     /locus_tag="IEZ14_RS18700"
                     /protein_end="67"
                     /protein_start="39"
                     /score="17.1"
                     /tool="antismash"
                     /translation="YATTCTVHLTGGLDVDRLAAAAEAVAAR"
     misc_feature    complement(2620..2635)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.82"
                     /tool="antismash"
     misc_feature    2628..2644
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.27"
                     /tool="antismash"
     misc_feature    2629..2643
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.49"
                     /tool="antismash"
     gene            complement(2681..4009)
                     /gene="thrC"
                     /locus_tag="IEZ14_RS18705"
                     /old_locus_tag="GCM10010177_37740"
     CDS             complement(2681..4009)
                     /EC_number="4.2.3.1"
                     /GO_function="GO:0004795 - threonine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thrC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR00260.1"
                     /locus_tag="IEZ14_RS18705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_37740"
                     /product="threonine synthase"
                     /protein_id="WP_179832841.1"
                     /sec_met_domain="PALP (E-value: 8.3e-79, bitscore: 259.4,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPKPVADADGMDHLRWECSRCAAFSPVGDLRYACTRCRWSGRLT
                     LVIDYERVGAGRPPADVLLTDEHSLWRYARLLPVGMDGGGSRRVRSRYVAGWTPMHRAD
                     RLARRLGLGRLWIKDEAANPSGALKDRASVVAVADALDRGRNVIATASSGNAGAALAGA
                     AAAVGLRCVVFVPRGTPATKVTQISRYGARVLVVDGDYDDAVRLSTAACRRWGWYCRNT
                     AYNPCTAEGKKTAALEIVEQLGWSAPDAVVVPVGDGNILVGLYRGLCDALAMGWIDRMP
                     RLIGVQAAASPAVHRAWAEGAADVSPAPARTRAESINVGEPQDGFRALAAVRDTAGLVV
                     AVEDEEIFAAVDWLAAESGVYPEPASAAGAAALPALVARGELGSADRVVLLNTGSGLKT
                     APSAEGGSAVPVAADLRAVAAIGITEAAETGSEADLDEPEPKW"
     gene            complement(4020..5270)
                     /locus_tag="IEZ14_RS18710"
                     /old_locus_tag="GCM10010177_37750"
     CDS             complement(4020..5270)
                     /NRPS_PKS="Domain: Aminotran_1_2 (54-396). E-value:
                     5.3e-45. Score: 146.0. Matches aSDomain:
                     nrpspksdomains_IEZ14_RS18710_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012382.5"
                     /locus_tag="IEZ14_RS18710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_37750"
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="WP_179832840.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 3.1e-44, bitscore:
                     146.0, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 3e-08, bitscore:
                     27.7, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVGQDTRPPTLAGSRLRPAISFEDERFLMFVLDEMAGDYEQRYD
                     DVIRLTLGKSELPPEPPIIAAMLDAAQDYAKASLVFPGGLPQLRRRLSAEYRSRYGVEV
                     PSERFVISVGTSMAFRNLTQLLAGPGDEVVVPLPYYPLYPFTARLAGARVRHYRIDLDT
                     LQVDMDSLAAAINERTRIVVVNSPGNPLGNVIDPATFRRIDEVVAGRAVLIADEIYNNV
                     HFDDEPYSAIALADEMTSPLVVTNAFSKAHRMYARRVGYAIVPDELVHPLTVIQHHTLL
                     TTDPVPQFGAIAALDHQDGVRSLTGRYGARRDYTLERLGQVSSVRAVPSRGSFYLTLDC
                     AEYLRRHDVPGSLALAERIMRATRVATVPGSDFGLPDTLRLSYTSARYEEGIDRLAGFF
                     TGAPPDVDADADAVPRG"
     aSDomain        complement(4083..5108)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS18710_Aminotran_1_2.1"
                     /evalue="5.30E-45"
                     /label="IEZ14_RS18710_Aminotran_1_2.1"
                     /locus_tag="IEZ14_RS18710"
                     /protein_end="396"
                     /protein_start="54"
                     /score="146.0"
                     /tool="antismash"
                     /translation="SELPPEPPIIAAMLDAAQDYAKASLVFPGGLPQLRRRLSAEYRSR
                     YGVEVPSERFVISVGTSMAFRNLTQLLAGPGDEVVVPLPYYPLYPFTARLAGARVRHYR
                     IDLDTLQVDMDSLAAAINERTRIVVVNSPGNPLGNVIDPATFRRIDEVVAGRAVLIADE
                     IYNNVHFDDEPYSAIALADEMTSPLVVTNAFSKAHRMYARRVGYAIVPDELVHPLTVIQ
                     HHTLLTTDPVPQFGAIAALDHQDGVRSLTGRYGARRDYTLERLGQVSSVRAVPSRGSFY
                     LTLDCAEYLRRHDVPGSLALAERIMRATRVATVPGSDFGLPDTLRLSYTSARYEEGIDR
                     LA"
     gene            complement(5312..8467)
                     /locus_tag="IEZ14_RS18715"
                     /old_locus_tag="GCM10010177_37760"
     CDS             complement(5312..8467)
                     /NRPS_PKS="Domain: Condensation_LCL (43-269). E-value:
                     1.7e-11. Score: 35.6. Matches aSDomain:
                     nrpspksdomains_IEZ14_RS18715_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (464-860). E-value: 2.1e-96.
                     Score: 314.9. Matches aSDomain:
                     nrpspksdomains_IEZ14_RS18715_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (976-1043). E-value: 1.6e-10. Score:
                     33.0. Matches aSDomain: nrpspksdomains_IEZ14_RS18715_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR01733.1"
                     /locus_tag="IEZ14_RS18715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_37760"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_179832839.1"
                     /sec_met_domain="Condensation (E-value: 2.6e-09, bitscore:
                     31.0, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 7.7e-105, bitscore:
                     345.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMTQGPVVHRDATAAGPGRIADVFPLTAWQQAALLADPGRASEVS
                     VAFDGPCDRPALVRALAGLVGRHPVLRSTVHLPPSGGPVHLVHPAPTTDPAEPALAGRP
                     RTGTDGGEVAELPTGPLGLPAASRCTVRRTSGGRVTVSLRLAGPLLDRRSSALLTTALL
                     RGYAAELRGRPSADAPPVTGMRDMVAAEWGAVTPEATGYWRRTLERVADGLAWRSPDAA
                     SARGAPAVAALPSDLATRLGRTAQRAGTSRDAVLLAAYLRVLALIGGTATAGTWLLDDA
                     RGPAGVDGGSLGDFRSLLPVSMCCDVPTWASLVERTDAALAAHRPYRSFPVAELVETGL
                     VPGALFEYCEMPAADRPPGGELLDAVEHTYTESPVAPLTLTVEDAAETGGMTLRLFRHG
                     GDPAEILGYYLRALTEITADVEGDPRTSAPLLGSVPPGPASVRPAESTPSSSAAAEDPA
                     TLHGLIARQAARTPDAPAVIDGDTVVGYNELYERVTVLADRIRTAGVAPQGLVGVHVPP
                     GADLVVALVAVLAAGCAFLPLDVRYPRRRCEFALGDAGADLLLTRSDVADRLDFTGPTM
                     ILDRRGDGPEERRPPLDRSSPESPAYVLYTSGSTGRPKGVVMPHSAVVEQVRWAVEAFG
                     LRPGDRVAQRTPVAFDAALWEFFAPLSCGAAVVTVPAGADRDIAALETVLTERAVTVLQ
                     VVPSLLAVLAESATFTRCPELRLVCCGGEALPQRLADAVIGHTEAALLNLYGPTEACVD
                     ATWWRAEAGARGTTVPIGHPVTGVRLYLLDELGQPVPPGTPGELFIGGAQLAWGYRGRP
                     AETAERFVPDHLSGRPGDRLYRTGDRARRLPGAELEFLNRTDDQVKVRGVRTEPGEVEA
                     ALTDHPRVRHAAVVPQREGAGEASDGMTLTAFVSWVGDPPGQHEEAVAELRDHLRGRVP
                     EAMVPTAFIALAEPPLLPNGKLDRRRLRSTDITGAGERYRPPADPVEERLASGFAGSLG
                     VDEVGRTDDLVWLGARPLHALRLAGRADPGNGAPLSAARVLGRPTVAQLAEAVAPEPRR
                     APS"
     aSDomain        complement(5339..5539)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS18715_PCP.1"
                     /evalue="1.60E-10"
                     /label="IEZ14_RS18715_PCP.1"
                     /locus_tag="IEZ14_RS18715"
                     /protein_end="1043"
                     /protein_start="976"
                     /score="33.0"
                     /tool="antismash"
                     /translation="EERLASGFAGSLGVDEVGRTDDLVWLGARPLHALRLAGRADPGNG
                     APLSAARVLGRPTVAQLAEAVA"
     aSModule        complement(5339..8338)
                     /complete
                     /domains="nrpspksdomains_IEZ14_RS18715_Condensation_LCL.1"
                     /domains="nrpspksdomains_IEZ14_RS18715_AMP-binding.1"
                     /domains="nrpspksdomains_IEZ14_RS18715_PCP.1"
                     /locus_tags="IEZ14_RS18715"
                     /monomer_pairings="Gln -> Gln"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(5858..5923)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS18715_0007"
                     /evalue="7.80E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="IEZ14_RS18715"
                     /protein_end="870"
                     /protein_start="848"
                     /score="27.8"
                     /tool="antismash"
                     /translation="FLNRTDDQVKVRGVRTEPGEVE"
     aSDomain        complement(5888..7075)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS18715_AMP-binding.1"
                     /evalue="2.10E-96"
                     /label="IEZ14_RS18715_AMP-binding.1"
                     /locus_tag="IEZ14_RS18715"
                     /protein_end="860"
                     /protein_start="464"
                     /score="314.9"
                     /specificity="substrate consensus: Gln"
                     /tool="antismash"
                     /translation="ARQAARTPDAPAVIDGDTVVGYNELYERVTVLADRIRTAGVAPQG
                     LVGVHVPPGADLVVALVAVLAAGCAFLPLDVRYPRRRCEFALGDAGADLLLTRSDVADR
                     LDFTGPTMILDRRGDGPEERRPPLDRSSPESPAYVLYTSGSTGRPKGVVMPHSAVVEQV
                     RWAVEAFGLRPGDRVAQRTPVAFDAALWEFFAPLSCGAAVVTVPAGADRDIAALETVLT
                     ERAVTVLQVVPSLLAVLAESATFTRCPELRLVCCGGEALPQRLADAVIGHTEAALLNLY
                     GPTEACVDATWWRAEAGARGTTVPIGHPVTGVRLYLLDELGQPVPPGTPGELFIGGAQL
                     AWGYRGRPAETAERFVPDHLSGRPGDRLYRTGDRARRLPGAELEFLNRTDDQVKVR"
     CDS_motif       complement(6011..6100)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS18715_0006"
                     /evalue="3.40E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="IEZ14_RS18715"
                     /protein_end="819"
                     /protein_start="789"
                     /score="44.9"
                     /tool="antismash"
                     /translation="PPGTPGELFIGGAQLAWGYRGRPAETAERF"
     CDS_motif       complement(6464..6487)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS18715_0005"
                     /evalue="9.90E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="IEZ14_RS18715"
                     /protein_end="668"
                     /protein_start="660"
                     /score="-2.9"
                     /tool="antismash"
                     /translation="LSCGAAVV"
     CDS_motif       complement(6608..6667)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS18715_0004"
                     /evalue="1.60E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="IEZ14_RS18715"
                     /protein_end="620"
                     /protein_start="600"
                     /score="32.7"
                     /tool="antismash"
                     /translation="AYVLYTSGSTGRPKGVVMPH"
     CDS_motif       complement(6851..6889)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS18715_0003"
                     /evalue="1.50E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="IEZ14_RS18715"
                     /protein_end="539"
                     /protein_start="526"
                     /score="12.1"
                     /tool="antismash"
                     /translation="AVLAAGCAFLPLD"
     aSDomain        complement(7661..8338)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS18715_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.70E-11"
                     /label="IEZ14_RS18715_Condensation_LCL.1"
                     /locus_tag="IEZ14_RS18715"
                     /protein_end="269"
                     /protein_start="43"
                     /score="35.6"
                     /specificity="C activity: inactive"
                     /specificity="Active site motif: AGPLLDR"
                     /tool="antismash"
                     /translation="VSVAFDGPCDRPALVRALAGLVGRHPVLRSTVHLPPSGGPVHLVH
                     PAPTTDPAEPALAGRPRTGTDGGEVAELPTGPLGLPAASRCTVRRTSGGRVTVSLRLAG
                     PLLDRRSSALLTTALLRGYAAELRGRPSADAPPVTGMRDMVAAEWGAVTPEATGYWRRT
                     LERVADGLAWRSPDAASARGAPAVAALPSDLATRLGRTAQRAGTSRDAVLLAAYLRVLA
                     LIGG"
     CDS_motif       complement(7673..7720)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS18715_0002"
                     /evalue="4.00E-03"
                     /label="Cy4"
                     /locus_tag="IEZ14_RS18715"
                     /protein_end="265"
                     /protein_start="249"
                     /score="10.3"
                     /tool="antismash"
                     /translation="TSRDAVLLAAYLRVLA"
     CDS_motif       complement(8243..8335)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS18715_0001"
                     /evalue="2.40E-08"
                     /label="C2_LCL_024-062"
                     /locus_tag="IEZ14_RS18715"
                     /protein_end="75"
                     /protein_start="44"
                     /score="26.4"
                     /tool="antismash"
                     /translation="SVAFDGPCDRPALVRALAGLVGRHPVLRSTV"
     gene            complement(8497..12918)
                     /locus_tag="IEZ14_RS18720"
                     /old_locus_tag="GCM10010177_37770"
     CDS             complement(8497..12918)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_DCL (7-307). E-value:
                     5.4e-104. Score: 339.4. Matches aSDomain:
                     nrpspksdomains_IEZ14_RS18720_Condensation_DCL.1"
                     /NRPS_PKS="Domain: PCP (924-986). E-value: 9.5e-20. Score:
                     62.6. Matches aSDomain: nrpspksdomains_IEZ14_RS18720_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1009-1309). E-value:
                     1.5e-98. Score: 321.5. Matches aSDomain:
                     nrpspksdomains_IEZ14_RS18720_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.5"
                     /locus_tag="IEZ14_RS18720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_37770"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_179832838.1"
                     /sec_met_domain="AMP-binding (E-value: 2.4e-16, bitscore:
                     53.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.5e-13, bitscore:
                     45.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 3.7e-68, bitscore:
                     224.2, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPDQIERICRLTPLQDGMFFEALRKQDSGETIYQLCLRLEGALS
                     PSLLRESWRAVIRRHPILRTSFHYERLDLPVQVVSDDAEPEWQESDWRGTPAEEIEQRL
                     NAMLDEDRTRPFELGRAPLMRLAVVRVADEAWWLVWSYHHLLLDGWSTYLVLDDVFGWY
                     RELAAGRLPERGAPRPFWEYVAWTQRQDLGRAESFWSERLAGFTEPTPIGGEAVDPPVR
                     NGPEFGEVHATLPPEVFTGLEALARTRRLTLGTVVQAAWALTLSRYSGREDVVFGSVVS
                     GRPPEFAGVDDMVGLFINVLPVRARVAGDTSLADWLTGLQAQLADGREYDYSPLAHVQR
                     WSEVPRGTALFESLVVYINYPVRPSWTDGGTVRVADLRVIQQPHYPLHLTVVPDQRRLR
                     MALGYDPVRFRRDTAERVRDLVVEILTIAATDPERRLGELPGWPEPVGRAAADDGVTTT
                     GVPSPGRSLDRLTGQCLRTPDAPAIICGDLTLTYGELDRRAERVADELRRSGAGPVAVM
                     LGPSAELAVGLLAVVKAGGTILPLDPDDGGERIGAAVAAAGATVVLCDGSHADSPAATD
                     QVTVGGDLRLLRLGEREAAEHPGAGPTPGGSAADAPSATRWAVLGHDAQEPAASLIRYD
                     ALAGLLHWMGEHFPLSADDRVAHLRSPGSAESVRDIFWTMSSGAALVLPPRAARPSAGV
                     SPAVLEEILVENEATVAVIPGSPPGSVASALGRCRSLRLVFVPGPVPTASRLELTQGTG
                     ADLVEEYRFPHPVPQSSFWHAGTGELVAAPLVARRRGHARVLPSAADADGPVPARNAGA
                     RQWAVEAVLAGHPGVRDAAVTVGTGPSGEQRLTAYVVPAGESVQDMPDAAELEEFLMLR
                     LPARLVPSAFVPLAAMPTARDGQPDVAALPAPEEDGGREAVPAASPAAVMIEVLTGIWA
                     QVFDRAPGVDEDFFDLGGHSLLAIKLVSRIRSALGVDFTLNDLFGDPTVIGTAHAVMAA
                     LRSGATLEPERAIPRCDRTGPIPASFAQERLWIMDRLGGAARHDNILLPCRLRGPVDVP
                     AFRAALAAVMERHELLRTRLDERDGRPVQVVHGSLEPPLAFSDLSSLPLPEAESRARTM
                     LEEDSAGRFDLSVAPLFKVRVVRLDDDDHVIGICLHHLAIDGWSTGVLFRDLGELYQRF
                     ADGREGTLAPLSAQYADFAAWQRRRLTGEPLDELLKYWVGRLRDAPEMLELQPGRPRPA
                     ERSHRGGRCDVDLTPDVLRIVRDLARQEGGTLFMVLFAAFAVLVARRAGRRDFVIGVPV
                     AGRSHPDLENLVGFFVNTLPVRLDLSGEPTFRRLLQHVRRVHLGALAHEDLPFERLVSE
                     LGPDRATDRVPLVQVAFNFQNAPFAPLRFGEVEATLFETDHEVARFDLVAELYEWEGGV
                     HCMFHYSADLFEPAFVGQFADEYLDLVRRLAAEPDGLVFATADGDVNVSAQVRQALDTS
                     SVNRLRALQGQG"
     CDS_motif       complement(8833..8952)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS18720_0011"
                     /evalue="6.80E-17"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="IEZ14_RS18720"
                     /protein_end="1362"
                     /protein_start="1322"
                     /score="53.8"
                     /tool="antismash"
                     /translation="RRVHLGALAHEDLPFERLVSELGPDRATDRVPLVQVAFNF"
     aSDomain        complement(8992..9891)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS18720_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.50E-98"
                     /label="IEZ14_RS18720_Condensation_LCL.1"
                     /locus_tag="IEZ14_RS18720"
                     /protein_end="1309"
                     /protein_start="1009"
                     /score="321.5"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLAIDG"
                     /tool="antismash"
                     /translation="PIPASFAQERLWIMDRLGGAARHDNILLPCRLRGPVDVPAFRAAL
                     AAVMERHELLRTRLDERDGRPVQVVHGSLEPPLAFSDLSSLPLPEAESRARTMLEEDSA
                     GRFDLSVAPLFKVRVVRLDDDDHVIGICLHHLAIDGWSTGVLFRDLGELYQRFADGREG
                     TLAPLSAQYADFAAWQRRRLTGEPLDELLKYWVGRLRDAPEMLELQPGRPRPAERSHRG
                     GRCDVDLTPDVLRIVRDLARQEGGTLFMVLFAAFAVLVARRAGRRDFVIGVPVAGRSHP
                     DLENLVGFFVNTLPVRLDL"
     CDS_motif       complement(9001..9090)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS18720_0010"
                     /evalue="2.00E-17"
                     /label="C5_LCL_267-296"
                     /locus_tag="IEZ14_RS18720"
                     /protein_end="1306"
                     /protein_start="1276"
                     /score="55.5"
                     /tool="antismash"
                     /translation="DFVIGVPVAGRSHPDLENLVGFFVNTLPVR"
     CDS_motif       complement(9343..9381)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS18720_0009"
                     /evalue="8.20E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="IEZ14_RS18720"
                     /protein_end="1192"
                     /protein_start="1179"
                     /score="18.3"
                     /tool="antismash"
                     /translation="QYADFAAWQRRRL"
     CDS_motif       complement(9430..9495)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS18720_0008"
                     /evalue="3.40E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="IEZ14_RS18720"
                     /protein_end="1163"
                     /protein_start="1141"
                     /score="32.4"
                     /tool="antismash"
                     /translation="LHHLAIDGWSTGVLFRDLGELY"
     CDS_motif       complement(9718..9819)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS18720_0007"
                     /evalue="6.10E-14"
                     /label="C2_LCL_024-062"
                     /locus_tag="IEZ14_RS18720"
                     /protein_end="1067"
                     /protein_start="1033"
                     /score="44.4"
                     /tool="antismash"
                     /translation="NILLPCRLRGPVDVPAFRAALAAVMERHELLRTR"
     aSDomain        complement(9961..10146)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS18720_PCP.1"
                     /evalue="9.50E-20"
                     /label="IEZ14_RS18720_PCP.1"
                     /locus_tag="IEZ14_RS18720"
                     /protein_end="986"
                     /protein_start="924"
                     /score="62.6"
                     /tool="antismash"
                     /translation="LTGIWAQVFDRAPGVDEDFFDLGGHSLLAIKLVSRIRSALGVDFT
                     LNDLFGDPTVIGTAHAV"
     aSModule        complement(9961..12897)
                     /domains="nrpspksdomains_IEZ14_RS18720_Condensation_DCL.1"
                     /domains="nrpspksdomains_IEZ14_RS18720_PCP.1"
                     /incomplete
                     /locus_tags="IEZ14_RS18720"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(11224..11262)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS18720_0006"
                     /evalue="2.20E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="IEZ14_RS18720"
                     /protein_end="565"
                     /protein_start="552"
                     /score="-0.4"
                     /tool="antismash"
                     /translation="AVAAAGATVVLCD"
     CDS_motif       complement(11293..11334)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS18720_0005"
                     /evalue="6.60E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="IEZ14_RS18720"
                     /protein_end="542"
                     /protein_start="528"
                     /score="10.2"
                     /tool="antismash"
                     /translation="LAVVKAGGTILPLD"
     CDS_motif       complement(11836..11958)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS18720_0004"
                     /evalue="2.10E-16"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="IEZ14_RS18720"
                     /protein_end="361"
                     /protein_start="320"
                     /score="52.3"
                     /tool="antismash"
                     /translation="QAQLADGREYDYSPLAHVQRWSEVPRGTALFESLVVYINYP"
     aSDomain        complement(11998..12897)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS18720_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="5.40E-104"
                     /label="IEZ14_RS18720_Condensation_DCL.1"
                     /locus_tag="IEZ14_RS18720"
                     /protein_end="307"
                     /protein_start="7"
                     /score="339.4"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLLLDG"
                     /tool="antismash"
                     /translation="RICRLTPLQDGMFFEALRKQDSGETIYQLCLRLEGALSPSLLRES
                     WRAVIRRHPILRTSFHYERLDLPVQVVSDDAEPEWQESDWRGTPAEEIEQRLNAMLDED
                     RTRPFELGRAPLMRLAVVRVADEAWWLVWSYHHLLLDGWSTYLVLDDVFGWYRELAAGR
                     LPERGAPRPFWEYVAWTQRQDLGRAESFWSERLAGFTEPTPIGGEAVDPPVRNGPEFGE
                     VHATLPPEVFTGLEALARTRRLTLGTVVQAAWALTLSRYSGREDVVFGSVVSGRPPEFA
                     GVDDMVGLFINVLPVRARV"
     CDS_motif       complement(12007..12102)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS18720_0003"
                     /evalue="2.00E-18"
                     /label="C5_DCL_263-294"
                     /locus_tag="IEZ14_RS18720"
                     /protein_end="304"
                     /protein_start="272"
                     /score="58.8"
                     /tool="antismash"
                     /translation="DVVFGSVVSGRPPEFAGVDDMVGLFINVLPVR"
     CDS_motif       complement(12433..12495)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS18720_0002"
                     /evalue="2.60E-06"
                     /label="C3_DCL_135-156"
                     /locus_tag="IEZ14_RS18720"
                     /protein_end="162"
                     /protein_start="141"
                     /score="20.0"
                     /tool="antismash"
                     /translation="YHHLLLDGWSTYLVLDDVFGW"
     CDS_motif       complement(12712..12816)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEZ14_RS18720_0001"
                     /evalue="1.50E-16"
                     /label="C2_DCL_024-062"
                     /locus_tag="IEZ14_RS18720"
                     /protein_end="69"
                     /protein_start="34"
                     /score="52.6"
                     /tool="antismash"
                     /translation="QLCLRLEGALSPSLLRESWRAVIRRHPILRTSFHY"
     gene            complement(12992..14026)
                     /locus_tag="IEZ14_RS18725"
                     /old_locus_tag="GCM10010177_37780"
     CDS             complement(12992..14026)
                     /EC_number="1.14.11.-"
                     /GO_function="GO:0051213 - dioxygenase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: TauD (31-321). E-value: 6.8e-42. Score:
                     136.0. Matches aSDomain:
                     nrpspksdomains_IEZ14_RS18725_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1046: Dioxygenase TauD/TfdA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017607018.1"
                     /locus_tag="IEZ14_RS18725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_37780"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_229810259.1"
                     /sec_met_domain="TauD (E-value: 3.9e-41, bitscore: 136.0,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVTVNDQAIAELGLSVGESGPPIAQAGETTSMATAREWLTERRG
                     AFGAALARYGCLLVRGLPIESVHDFAGARDVLLDQRVSYREKATPRSDYGEGVLSSTDL
                     PSAQVIRLHNENSYTLDFPGILLFGCLVAPEEGGATTVADTREVLARVPAELADRFRRL
                     GWVLARNYREHVSLPWSTAFGTSDRARVEDYCRRSSIGYRWLPDGGLATTQRRATTIHH
                     PGTGEEVWFNHIAFWNQHSLDPDIRDVLLTSYGPDGLPFDTLYGDGSPIDAEDIAALNA
                     AYDGAQRREPWRPGDLLLVDNILSCHGREAFRGDRKILVAMGEQVSLADCRPTVEPAPE
                     PVAG"
     aSDomain        complement(13064..13933)
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS18725_TauD.1"
                     /evalue="6.80E-42"
                     /label="IEZ14_RS18725_TauD.1"
                     /locus_tag="IEZ14_RS18725"
                     /protein_end="321"
                     /protein_start="31"
                     /score="136.0"
                     /tool="antismash"
                     /translation="SMATAREWLTERRGAFGAALARYGCLLVRGLPIESVHDFAGARDV
                     LLDQRVSYREKATPRSDYGEGVLSSTDLPSAQVIRLHNENSYTLDFPGILLFGCLVAPE
                     EGGATTVADTREVLARVPAELADRFRRLGWVLARNYREHVSLPWSTAFGTSDRARVEDY
                     CRRSSIGYRWLPDGGLATTQRRATTIHHPGTGEEVWFNHIAFWNQHSLDPDIRDVLLTS
                     YGPDGLPFDTLYGDGSPIDAEDIAALNAAYDGAQRREPWRPGDLLLVDNILSCHGREAF
                     RGDRKILVA"
     gene            complement(14017..15075)
                     /locus_tag="IEZ14_RS18730"
                     /old_locus_tag="GCM10010177_37790"
     CDS             complement(14017..15075)
                     /EC_number="1.14.11.-"
                     /GO_function="GO:0051213 - dioxygenase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: TauD (35-321). E-value: 1.8e-43. Score:
                     141.2. Matches aSDomain:
                     nrpspksdomains_IEZ14_RS18730_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1046: Dioxygenase TauD/TfdA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014698.5"
                     /locus_tag="IEZ14_RS18730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_37790"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_179832837.1"
                     /sec_met_domain="TauD (E-value: 1e-42, bitscore: 141.2,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVRHAGRDSSDGADAAAADGAPTLVRVDGVADAASAQAWLADNRE
                     RVLTELRRHGSLMIRGLPLASPEHFAAARDVLLEDHLEVPREETTPRTGYGNGIFSATD
                     LPPVQRIRLHCEDSYSVVFPGILLFCCLVPPERGGATTLGDTRRVLAALPADLVERFRR
                     RGWMIVRNFQKHVGMPWQQAFGTADRAAVESYCDQNQLSYEWLPDDRLRTSGVRSATVR
                     HPSTGEESWFNHVAVFNEWTHDPETREILVAACGPDGLPQNTYYGDGSPIDPADVAVIN
                     RAFDEVMVRESWRRGDLVLVDNLLCSHGREPFTGDRRVLVAMGEPRRMADCSPSGPIGP
                     AAARGPGKEGWT"
     aSDomain        complement(14113..14970)
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEZ14_RS18730_TauD.1"
                     /evalue="1.80E-43"
                     /label="IEZ14_RS18730_TauD.1"
                     /locus_tag="IEZ14_RS18730"
                     /protein_end="321"
                     /protein_start="35"
                     /score="141.2"
                     /tool="antismash"
                     /translation="AQAWLADNRERVLTELRRHGSLMIRGLPLASPEHFAAARDVLLED
                     HLEVPREETTPRTGYGNGIFSATDLPPVQRIRLHCEDSYSVVFPGILLFCCLVPPERGG
                     ATTLGDTRRVLAALPADLVERFRRRGWMIVRNFQKHVGMPWQQAFGTADRAAVESYCDQ
                     NQLSYEWLPDDRLRTSGVRSATVRHPSTGEESWFNHVAVFNEWTHDPETREILVAACGP
                     DGLPQNTYYGDGSPIDPADVAVINRAFDEVMVRESWRRGDLVLVDNLLCSHGREPFTGD
                     RRVLV"
     misc_feature    complement(14296..14298)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(15079..15381)
                     /locus_tag="IEZ14_RS18735"
                     /old_locus_tag="GCM10010177_37800"
     CDS             complement(15079..15381)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1147: putative acyl carrier protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEZ14_RS18735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010177_37800"
                     /product="phosphopantetheine-binding protein"
                     /protein_id="WP_218934992.1"
                     /sec_met_domain="PP-binding (E-value: 1.3e-05, bitscore:
                     20.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDGELGGNSREPDGGRVIAMVREFVSQHTGGASIADDVDIFATGF
                     VSSLFAVQILTWVERTFDLAVSGDDLDIANFMSVDAITRFVLGKRAVAPTGPIGG"
     gene            complement(15419..16276)
                     /locus_tag="IEZ14_RS18740"
                     /old_locus_tag="GCM10010177_37810"
     CDS             complement(15419..16276)
                     /EC_number="1.1.1.35"
                     /GO_function="GO:0003857 - 3-hydroxyacyl-CoA dehydrogenase
                     activity [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /GO_process="GO:0006635 - fatty acid beta-oxidation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1095: 3-hydroxybutyryl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017617823.1"
                     /locus_tag="IEZ14_RS18740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_37810"
                     /product="3-hydroxyacyl-CoA dehydrogenase family protein"
                     /protein_id="WP_179832836.1"
                     /transl_table=11
                     /translation="MIQTVGVVGAGTIGTGVAHAFAEAGYPVTLIDISEAALKTARETI
                     AGNARLLPVVVGRPAKRTPDEILALITPTTDLGDLRGADYVVENVTEKWAVKKDLYRSL
                     DRVCGPECVLAVNTSAIPITRLAGCTGRPDKVIGNHFMNPVPVMPLVEIIRGVHTSDAT
                     LELSRGLLADIGKETVLVGDSSGFVTNRVLMLTINEAIFLLHEQVSSPKDIDRLFKKCF
                     GHRMGPMETADLIGLDTVLYSLEVLLEEFQDPKYRPCPLLRRYVDAGHLGRKTGRGFHV
                     YDHD"
     gene            complement(16273..17532)
                     /locus_tag="IEZ14_RS18745"
                     /old_locus_tag="GCM10010177_37820"
     CDS             complement(16273..17532)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEZ14_RS18745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010177_37820"
                     /product="hypothetical protein"
                     /protein_id="WP_179832835.1"
                     /transl_table=11
                     /translation="MSTRPSRNGRPGGRATEHTVRLPRPVPSELATELARRIFFVSEDI
                     ASFRLLRGQGDAVDAVLLRTGTAEPTAALSRKLRRMVRMDVLGQLARPPKVVWRSTRTT
                     DTRPDIFEALADRGAAFEAGEGQIAVGEPVLTLMDRFDGMLREIAVTELGATEFRYPTL
                     VPTGALQRSGYFSAFPQHVMLATRLRGDLDVYRKFTERDHDEGHVGEAMLAHCRNADYC
                     LPPTMCYHTFHQYAGKRLSSPSTVVTARGKSFRYEGRYHTSLERLWDFTIREIVFMGER
                     EQVLDGRERFLRRAIELVERLGLSGRCEVATDPFFCAADGASRISAQRLLELKYELRLD
                     IAPDATVAVGSFNFHEQHFGTAFDITGRDRGPVWTGCVGFGLERLAYAFVCQHGLDESG
                     WPEEFRGDERGRPHGRGVDR"
     gene            complement(17529..18689)
                     /locus_tag="IEZ14_RS18750"
                     /old_locus_tag="GCM10010177_37830"
     CDS             complement(17529..18689)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012656.5"
                     /locus_tag="IEZ14_RS18750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_37830"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_179832834.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.5e-22, bitscore:
                     74.1, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.2e-28, bitscore:
                     93.6, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2.9e-41, bitscore:
                     135.6, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFAISPWQRELCAETVRFARQELGGRTGDSDRSGSLDTDGWQKA
                     ADFGALGWPVPRDHGGSGFDPLTSALAFEALGYGCSNNGLLFAINNHVWACAIYLVKYG
                     TEHQKARWLPELCKGTVIGAHALTEPQAGSDMLALATTAHRSGSGWVLNGTKTFISNGS
                     CADLFVTFARTSESEAPERGLSAFLVRADAPGVRIARELEKAGLRGAPMGEIQFSDVRL
                     DEEHLLGREGAGHQIFTSTIEWERGFLFASGVGTLRRLLETCVDHAAKREQFGRPIGSF
                     QAVSHTLADMRIRLELAQLMLYKFGWLKREGRLAMLESSILKLVVSEGLLETALEAVQI
                     HGARGYLTEGGMERELRDALAGTIYGGTSQIQRSIIASLLGLPGAP"
     misc_feature    complement(18342..18344)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            18905..19453
                     /locus_tag="IEZ14_RS18755"
                     /old_locus_tag="GCM10010177_37840"
     CDS             18905..19453
                     /EC_number="2.3.-.-"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012792.5"
                     /locus_tag="IEZ14_RS18755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_37840"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_179832833.1"
                     /transl_table=11
                     /translation="MLLRMATPADLSALLGIYDSTLRWLAERGTDQWQEPRLEPEMMKA
                     AILASIHHRQTWCAIDEQGGHAGLVTIKPHTPPGLWRPEEESEPHRYLYLALVSRENTG
                     VGLGADLVDWAVTRAAKAGARWARGDVWTANKPLQEYYLRHGWQLVRYVHRPDQPSGAL
                     IQRPAVPCETPRLVEVPET"
     misc_feature    19911..19927
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.88"
                     /tool="antismash"
     misc_feature    19920..19933
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.79"
                     /tool="antismash"
     gene            20093..21061
                     /locus_tag="IEZ14_RS18760"
                     /old_locus_tag="GCM10010177_37850"
     CDS             20093..21061
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEZ14_RS18760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010177_37850"
                     /product="hypothetical protein"
                     /protein_id="WP_179832832.1"
                     /transl_table=11
                     /translation="MDFTKPKAGGELDKSSEAAPPQGKLAALVVAALVIGETGVILQLF
                     FNVIKEEGAIMTSFLQTVVGTALLWCVVRPNLKAGWPLWWRSLAIGGSSVLSLVAAREA
                     MTLVPYGTITCLAFVFGPMAAASFRIIRARMMRTLIWPLLAAASVFLLVDGLGSGDLVG
                     FGLIALVALAYHVYATTTSGLQRDEVNTVATLARLPTVLLLTGMLFSAEEPDALLHVSG
                     EAWWVCSVSGAVGVVALLMINAAWKRGLTVTTHASVMPADNGLAMVDGMIAGQFPSLAN
                     WLGAGLVIISEVGATRARIPDRKQPPKFSMWLDGLPARFKG"
     gene            complement(21219..22220)
                     /locus_tag="IEZ14_RS18765"
                     /old_locus_tag="GCM10010177_37860"
     CDS             complement(21219..22220)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014913455.1"
                     /locus_tag="IEZ14_RS18765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_37860"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_179832831.1"
                     /transl_table=11
                     /translation="MQLQQLAYFVAVAEVRHFTQAAELLRVAQPSLSKQIRALENELNV
                     SLFSRARGNITLTPAGEALLPLAKRILADVDTARLEVQELVGLKRGRVRLGATPSLCAG
                     LLADVLRRFHDTYPGIQLIVEEGGSRDLVRELTRGSLDMALVILPLHGDPPLDTTPILR
                     EYLVVASPAGPGPDAPERSPRAAQLPRRSYLRIEDLQNRPLVMFRAGYDLREATISACR
                     AAGFEPRFAVEGGEMDAVLRFVEVGLGIAVVPSMVLAGRPGLRGTPLVLADEETRRGRH
                     GPGLLRTIALAHRKDVELTHAARAFQETLQTFLVEAALAGSLPAGVETLVTA"
     gene            complement(22333..23025)
                     /locus_tag="IEZ14_RS18770"
                     /old_locus_tag="GCM10010177_37870"
     CDS             complement(22333..23025)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0030552 - cAMP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012851487.1"
                     /locus_tag="IEZ14_RS18770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_37870"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_179832830.1"
                     /transl_table=11
                     /translation="MSALEGSFLGDLTPVEREELAARGRVRDFDRGETLFVEGEDPGWV
                     AVLLRGRVKACSYREFGGETILAVRGPGALLGEVAAIDGLPRSATVIALEPVGALAVTA
                     DEFMAFLQVHGRVSVLIMRMLCQRWRDADRKRVEFGMFDATGRVAQRLVELAERFGVPY
                     DRRTGAAGGDSVQITLNLSQEELAGWVGASREAVSKALRTLRRHGWIETGRRRLIVHDL
                     QALRRHAR"
     misc_feature    complement(22693..22695)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    23001..23014
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.74"
                     /tool="antismash"
     gene            complement(23351..24121)
                     /locus_tag="IEZ14_RS18775"
                     /old_locus_tag="GCM10010177_37880"
     CDS             complement(23351..24121)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018655751.1"
                     /locus_tag="IEZ14_RS18775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_37880"
                     /product="succinate dehydrogenase/fumarate reductase
                     iron-sulfur subunit"
                     /protein_id="WP_179832829.1"
                     /transl_table=11
                     /translation="MSYEAKFKVWRGDDGTGELTDYTVEVNEGEVVLDIIHRLQATQAP
                     DLAVRWNCKAGKCGSCSAEINGMPRLLCMTRMSTFDPEETITVTPVRTFPVIRDLVTDV
                     SYNYQKAREVPSFDPGDAKPGELRMQQVDVERSQEFRKCIECFLCQNVCHVIRDHEENK
                     PEYAGPRYLMRIAELEMHPADQADRRNIAQDDHGLGFCNITKCCTEVCPEHIKITDNAL
                     IPMKERVVGRKYDPLVWLGSKLGIVRKGEDTPSA"
     gene            complement(24118..26121)
                     /locus_tag="IEZ14_RS18780"
                     /old_locus_tag="GCM10010177_37890"
     CDS             complement(24118..26121)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017620091.1"
                     /locus_tag="IEZ14_RS18780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_37890"
                     /product="fumarate reductase/succinate dehydrogenase
                     flavoprotein subunit"
                     /protein_id="WP_179832828.1"
                     /transl_table=11
                     /translation="MTEIERHLYDVVVIGAGGAGLRAAIEARLQGKKTAIISKSLFGKA
                     HTVMAEGGAAAAMGNVNANDNWMVHFRDTMRGGKFMNSWRMAELHAKEAPERIWELELW
                     GALFDRTKDGKISQRNFGGHEYPRLAHVGDRTGLELIRTAQQKIVALQQEDHAEHGDYE
                     ARLKVWSETTVTRLLKDPDGRICGAFGYVRETGRFVVFEAPAVVLATGGIGKAFKVTSN
                     SWEYTGDGHALALLSGGSLLNMEFVQFHPTGMVWPPSVKGILVTESVRGDRGVLRNSEG
                     KRFMFDYIPEVFKNQYATTEEEGDRWYDDPDNNKRPPELLPRDEVARAINSEVKAGRGS
                     PHGGVFLTVVDRMPGGAAEIVKRLPSMYHQFKELADVDITKEPMEVGPTCHYVMGGVEV
                     EPDTGAAKVPGLFAAGEVSGGMHGSNRLGGNSLSDLLVFGRRAGLGASEYVDALPARPA
                     VPDAEIEAATAEAMAPFEREGGENPYAVHAELQQTMNELVGIIRKEEELQQAIASLGKL
                     RERVANVSVDPVAVGDGRGYHPGWHLALDLRNMLLVSEAVAKAALERQESRGGHTRDDY
                     PGMSAEWRKINLVCSLAGDPSSPHVELRRQPLTPMRTDLLELFDNDELKKYLTAEELPT
                     APAEQASAGDAKDAPEPDAAAADAAENEEDGR"
     gene            complement(26134..26964)
                     /locus_tag="IEZ14_RS18785"
                     /old_locus_tag="GCM10010177_37900"
     CDS             complement(26134..26964)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630074.1"
                     /locus_tag="IEZ14_RS18785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_37900"
                     /product="hypothetical protein"
                     /protein_id="WP_179832827.1"
                     /transl_table=11
                     /translation="MTTVEAPAKSRAQIKERTLRKDNWRLYPVTTFVIFTAWVVYATVR
                     AFWGAAFYVPEFHYLTPFYSPCLNEICNNVTVDGHTGDAAEFGTFLPAATRGWIPFAAI
                     SLPFLLLFRLTCYYYRKAYYRSFWASPSACAVREPHGKYTGERRFPLIGQNLHRYFWLA
                     AFAISLINTWDAVRAFHGKDGGFGIGLGTIILVANVVLLWLYTLSCHSCRHVVGGRLKN
                     FSKHPFRYRMWGWVSKINQRHGMYALITLGSLVVADLYVALVASNTISDLRIFN"
     misc_feature    complement(27116..27131)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.79"
                     /tool="antismash"
     misc_feature    complement(27159..27174)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.55"
                     /tool="antismash"
     misc_feature    27187..27202
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.03"
                     /tool="antismash"
     gene            complement(27262..27900)
                     /locus_tag="IEZ14_RS18790"
                     /old_locus_tag="GCM10010177_37910"
     CDS             complement(27262..27900)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEZ14_RS18790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010177_37910"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_179832826.1"
                     /transl_table=11
                     /translation="MSVAEDTIARNRALQAEWYGEPLGDRVRPLLGRLGMSQSGLAGVL
                     GLSAPMLSQLMSGQRAKISNPAVLHRLMAVEDLVAGPGFDALTAAGLQARLEGIKGESA
                     ATTSGMRGAVSGRVPTGPVPAGPEGAAERAAAEPARLVQALLREVASAAEIEAAAGLVA
                     DRFPDLAEVLRVYGTGRTSEAEAHFARTVLKQTPDDRTVMPERSRLDSL"
     misc_feature    27919..27934
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 22.59"
                     /tool="antismash"
     misc_feature    27930..27943
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.19"
                     /tool="antismash"
     gene            28030..28605
                     /locus_tag="IEZ14_RS18795"
                     /old_locus_tag="GCM10010177_37920"
     CDS             28030..28605
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEZ14_RS18795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010177_37920"
                     /product="hypothetical protein"
                     /protein_id="WP_179832825.1"
                     /transl_table=11
                     /translation="MGLAHRLAAATATALLLTGGLAGCSLPGTGSSSNSPSSPSGGKKA
                     EGSVGRASFDNASKPLVKGTFDSPLAQGAKIDIAVMGLKTRGRLATLTMQLTPHVPPGG
                     PTRINAYGLNGEHGLGTSLIDPVNLKRYVVVKDTGGKELETDDIFTHMTNDQVTPFYFT
                     FAAPPENVKTVDVQIGTWPTFRDIPVER"
     gene            28602..29168
                     /locus_tag="IEZ14_RS18800"
                     /old_locus_tag="GCM10010177_37930"
     CDS             28602..29168
                     /GO_function="GO:0015288 - porin activity [Evidence IEA]"
                     /GO_function="GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017622046.1"
                     /locus_tag="IEZ14_RS18800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_37930"
                     /product="OmpA family protein"
                     /protein_id="WP_179832824.1"
                     /transl_table=11
                     /translation="MSRLRRPAVLAGVLALVLAVPAVAGADPGVPDQNLAESVHSIETG
                     ASVYGIDLQQAVIPLEEEEGDGGQVTVRISADVLFDFGKATLTGAARRRIAELAPRLRG
                     ARGAVQVSGHSDSIGDSAYNLALSEQRAEAVKAELANALTGTSPQIEARGYGETKPVVP
                     NEQGGKDDPAGRAKNRRVEITYEKG"
     gene            29174..30322
                     /locus_tag="IEZ14_RS18805"
                     /old_locus_tag="GCM10010177_37940"
     CDS             29174..30322
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012894.5"
                     /locus_tag="IEZ14_RS18805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_37940"
                     /product="OmpA family protein"
                     /protein_id="WP_179832823.1"
                     /transl_table=11
                     /translation="MRRASRASAVVLAAGLSLAACGGEGRPERAGGGHDRTGGAPESPA
                     ATVPAPEPSSCPGGGRLIKAVEIPAVHSEPVRIPEAVIGGQKIPAVTIPGVDLPAQRVP
                     AQCVEHRPAPGGCLGAVAIPGASIPGVTIPAVRIPGVRAPGIDAPPVEQAAVSSTAVSQ
                     QAVTGAEVCQSKPSKEGEYVSSVYRASLYRASLYRASAYRSSLYRPRTCNDNNECLPQV
                     SVPGVSVPGVSVPGVSVPGATLKSYVAGPGQVIKGDDSIAYNIEADVLFDFGAAEIKPA
                     AAAELKKIVESLGREVPAGAAVQVDGHTDGKGDTASNQALSLRRAQAIVDWLAAEGGIA
                     RSRLRATGYGETKPAYPNTEPDGSDDPEGRAKNRRVVISAAR"
     gene            complement(30324..31178)
                     /locus_tag="IEZ14_RS18810"
                     /old_locus_tag="GCM10010177_37950"
     CDS             complement(30324..31178)
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019334.5"
                     /locus_tag="IEZ14_RS18810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_37950"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_179832822.1"
                     /sec_met_domain="Pkinase (E-value: 3.8e-38, bitscore:
                     125.7, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSGWVIGGRFTMLDRIGAGGTSRVWRAYDHAEGRYCAAKLVRQP
                     GPTSMLRVVRERALRMAHPHVLTPYASCTAYDDVLLAMDLVRGGSLETLLGDYGRLPPG
                     YAAEVLDQLLAALSHIHGAGVVHRDVKPANLLLEPSPVGAPHVRLADFGIALGEADQRF
                     TTTGFAVGTPGYLAPEVLDWDRPGPRQDLYAAGMVAWRMLTGAGDPEPRQRIGAPPPGV
                     PPLLWAVVAHLCAADPGRRPAHADAARGALAACRLELRFPVRTLDGEPLQIFDHLGPPP
                     APA"
     misc_feature    complement(31240..31253)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.1"
                     /tool="antismash"
     misc_feature    complement(31664..31679)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     misc_feature    32102..32118
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.65"
                     /tool="antismash"
ORIGIN
        1 gtcaaacccg gccgccccaa atacccacgc gccaaaccag caccacccac gaacaactcc
       61 cccaccacac caggcggcac gggatgcagt tctccgtcga gtacgtaagc gctcaggtcc
      121 gggagcggaa ctccgatggg gctccgctcg gaggacgggg aatccggcgc ctcggcgaaa
      181 tcggccgcgg ggacgtcggc cgccgacagc gggtagtagg tcgcgtgcac cgtggtctcg
      241 gtgatgccgt acatgttgac cagccgcggc gcctggtcgc cgttgcgggc gaaccagccg
      301 gtgagcatgc cgggcatcag ggcttcgccg ccgaacacca ccacgcgcag cgccggccat
      361 ccctcggtgg cgtccgcgtc ctcggcggcc atcaggttgc ggaaggcccc cggcgtctgg
      421 ttgagcacgg tcacccgctc ccgcaccagg agggcgcgga acttctccgg cgaccgtgtc
      481 acggccgtcg gcacgacgac cgcccggccg ccgctcacca gcgcgcccca gagctcccag
      541 gccgcgaagt cgaacgtgac ggtgtggaac agcgtccaga tgtcgtccgg cccgaaggag
      601 aaccacggcc gggtggcggt cagcagccgg acgagagcgg catgggtgac catcaccccc
      661 ttgggccgtc cggtcgaccc ggaggtgtag atgacgtaga gcagactgcc gggcaccgtg
      721 ttcggcggcg gcgcctcggc aggccaccgg tcgatcgccg ccgcgtcctc gtccatccgt
      781 accgtcggca gatccgttcc cgcgggtgcc cgctcgcccg cccgcccgga cgtgacgagg
      841 atccgcacac cggcgtcgtc gaggacgtag gcgatccgct ccccgggatg atccgggtcc
      901 accgggacat aggccccgcc cgacttgacg accgcgagca gtgcgatgac cagttcgatc
      961 gagcggggca ggcagacccc cacccgcacc tccggaccgg ccccgagcgc gcgcaggtga
     1021 tgagcgagcc ggttggcccg gcgttccagc tccccgtagg tcaggcgttg cgtgccgcac
     1081 accacggcca cgccctcggg ccgccgcgcg gcctgctcct ccaccagtgc cgcaaggcat
     1141 gccccggatg gttcgctctc cgggtcccct cccgatcgca gcagcagccg tcgtccttcc
     1201 ggccccagaa ggtccaggtc ccggcaggcg ctgtcgggcc ggtccagcga gtcggccacc
     1261 agtgccagga aggagtccat cagctgcccg gcggcggaac gcggcaacgc gtcgccgtcg
     1321 tacccgagcg tgaaccgcat ccgctccccg gtgtcctggc aggaaaggcg gaccaggaac
     1381 ctgtcgtggt ggccgtacga ctcggtcggg ccggcgccgt cgtggtccgc gggccgttgc
     1441 ccggcgtcga agtcgaagcc gatcgggaac caggacggcc ggccgggcgc ggcgggggga
     1501 acgcagcgct cccagctgta ccactcggcg tgagcatcgc ccgcctcgat ctgctcggcc
     1561 gtctcggcgg cggcggccga gacggcgacg tcgagcggcc ggtcgaggcg cacgggcagg
     1621 gtgacggtca acggcccgga gcagccccgc agctcctcgt gccggcgcag gtccgtcgcc
     1681 acgccgacga ccagggcgcc ggcgccggtc atcctgcgga gcagcacctg ccagcaggcc
     1741 agcagccagc cgcgtgcgtc gttcggcgag gggcaccggc ggcgcagcgc catggtctcg
     1801 gcggggggaa ggaaaccggt cagggcctga gggcggaacg gcccggcccg gtgcttgcgc
     1861 tgccccggca gctctatcgg ctgatcccac ccggcgcagc gggaacgcca gaactcccgg
     1921 gccgtcgccc cctccggcag ctcggccatc tcgttccacc aggcggccac gccgtcgtac
     1981 ggcaggccgc cggcacgggg ggtgcggccc gccgcgcgtt cgacgacctc atgggccagg
     2041 ctccgcatcg tcgtgacatc ggcgcagatg gccggaagcg agaaggtgac cgcgtgacgg
     2101 ccctcggcca gccgtacggc gaggacgttg agttcgacgc cctcggtcag cggagtccgg
     2161 tgttccacct ctgccgcgtg ttccgccggt tcggccgcgc cttcggcacg gtcagggcac
     2221 atcaggtcga ggcggcggaa cgtgatccgg ggccgggcgg cgaccgtctg gacgggaccc
     2281 gttcgggccg ccgccgaatc atcgtggggg gagaacacca gccgcgactc ggtgcggcgg
     2341 gcggcgacgg cctcggccgc agcggcgagg cggtcgacgt ccaggccgcc ggtcaggtgc
     2401 acggtgcacg tcgtcgcgta cgggccgacc ccggggcctc cttgcagccg ccagagccgg
     2461 cgctgcgcgg gagtcagcgg aatggcggcg gcgcggtggt cgcgtggaaa cccggtttcg
     2521 aattccccgt catccatgtt ttggtggccc tcctcgcttg cgcgcatcag gtgcgccggc
     2581 gcccgcgctg agcggcatgc ccagcatcca tattcagtgg gtcacgtttg taattcatgt
     2641 cccacaaacc ggtgacatgc gatatcagaa agccgccgca ctaccatttt ggttctggct
     2701 cgtcaaggtc ggcttcactg ccggtctccg ccgcctcggt gatgccgatg gcggccacgg
     2761 cccgcaggtc ggccgccacc gggacggcgc tcccgccctc cgcggaaggc gcggtcttca
     2821 gtccgctgcc ggtgttgagc agaacgacgc ggtccgcgct cccgagctcc ccccgcgcca
     2881 cgagggcggg cagtgcggcg gctccggccg cactggccgg ctcgggatac acgccgcttt
     2941 ccgcggcgag ccagtcgacc gcggcgaata tctcctcgtc ctccaccgcg accacgagtc
     3001 ccgcggtgtc ccgcaccgcc gccagagccc ggaatccgtc ctgcggctcc ccgacgttga
     3061 tgctctcggc gcgcgtgcgg gccggagccg ggctgacgtc cgcggcgccc tcggcccagg
     3121 cgcggtgaac cgccggcgag gcggcggcct gcaccccgat caggcgcggc atgcggtcga
     3181 tccagcccat cgccagggca tcgcacagcc ctctgtacag gccgaccagg atgttcccgt
     3241 cccccacggg caccaccacc gcgtccggcg cggaccagcc gagctgctcg acgatctcca
     3301 gagcggcggt cttcttgccc tcggcggtgc aggggttgta cgcggtgttc cggcagtacc
     3361 aaccccatcg ccggcacgcc gccgtgctca gccggacggc gtcgtcgtag tcgccgtcga
     3421 ccaccaggac gcgcgccccg taccggctga tctgggtgac cttcgtcgcc ggggtgccgc
     3481 ggggcacgaa gaccacgcac cgcaggccga ccgccgcggc cgcgccggcg agcgcggccc
     3541 ccgcgttgcc cgaggacgcc gtggcgatca cgttccggcc gcggtcgagc gcgtcggcga
     3601 ccgcgacgac gctggcccgg tccttgaggg ctccggacgg gttggcggcc tcgtccttga
     3661 tccacagtcg gcccagcccc agccgccggg cgagccggtc ggcccggtgc atcggggtcc
     3721 agccggccac gtaccgggac ctgacccggc gggaaccgcc cccgtccatg ccgacgggca
     3781 gcaggcgggc gtaccgccag agggagtgct cgtcggtgag cagcacgtcg gcgggcggcc
     3841 ggcccgcacc gacccgctcg tagtcgatga ccagggtcag cctgccggac caccggcacc
     3901 gggtgcacgc gtagcgcagg tcgccgaccg gcgagaaggc ggcacatcgc gagcactccc
     3961 accgcaggtg gtccatgccg tcggcgtcgg ccacgggctt cggcgtcatc gccgattcct
     4021 caacctcgcg gcacggcgtc ggcgtccgcg tcgacgtccg gaggggctcc cgtgaagaag
     4081 ccggccagac ggtcgatgcc ctcctcgtag cgggcggagg tgtaggagag ccgtagcgtg
     4141 tccggcaagc cgaagtccga gccgggcacg gtcgccaccc gcgtcgcccg catgatgcgc
     4201 tcggccaggg cgagcgaacc ggggacgtcg tgccggcgca gatactcggc gcagtcgagg
     4261 gtcagataga agctcccccg ggaagggacg gcccgcaccg aggaaacctg gccaaggcgt
     4321 tcgagcgtgt agtcgcgccg ggcgccgtag cgaccggtca gcgaccgcac gccgtcctgg
     4381 tggtcgagcg ccgcgatggc gccgaactgc ggcaccggat cggtggtgag aagggtgtgg
     4441 tgctggatga cggtgagcgg gtggaccagc tcgtccggga cgatggcgta gccgacccgc
     4501 cgcgcgtaca tccggtgggc cttggagaac gcgttcgtca ccaccagcgg actggtcatc
     4561 tcgtcggcca gggcgatggc cgaatacggt tcgtcgtcga agtggacgtt gttgtagatc
     4621 tcgtcggcga tcagcacggc gcgaccggcg acgacctcgt cgatccgccg gaaggtcgcg
     4681 ggatcgatga cgttccccag cgggttccca ggggagttga ccaccacgat ccgggtgcgc
     4741 tcgttgatcg ccgcggccag cgagtccatg tccacctgga gcgtgtcgag gtcgatgcgg
     4801 taatgccgga cccgagcgcc ggccagtcgc gcggtgaagg ggtagagcgg gtagtagggc
     4861 aggggcacga ccacctcgtc gcccgggccg gccagcagct gggtgagatt ccggaaagcc
     4921 atgctggtgc ccacgctgat gacgaaccgt tcggacggca cctcgacgcc gtagcggctc
     4981 cggtactcgg cggacaaccg gcggcgcagc tgcggaaggc cgcccgggaa gaccagactc
     5041 gccttcgcgt agtcctgtgc cgcgtccagc atggccgcga tgatgggcgg ttccggcggc
     5101 agctcggact tgccgagcgt gagccggatg acgtcgtcat atcgctgctc gtagtcaccc
     5161 gccatctcgt cgaggacgaa catgaggaac cgttcgtcct cgaaggagat cgccggacgc
     5221 agccggctcc ccgcgagcgt gggcggccgg gtgtcctgtc caacggtcat ggtgcctcct
     5281 gagaccggcg agttgagatg gtccgggctg atcacgatgg ggctcggcgg ggctcgggtg
     5341 cgacggcctc cgccagctgg gcgaccgtcg gccggccgag gacccgggcg gccgagagcg
     5401 gtgcaccgtt ccccgggtcg gcccgcccgg cgaggcgcag ggcgtgcaga gggcgggccc
     5461 ccagccagac gaggtcgtcg gtccttccca cctcgtccac gccgagcgac ccggcgaagc
     5521 cggacgcgag ccgttcctcg acggggtcgg ccggtggccg gtacctttca ccggctccgg
     5581 tgatgtcggt gctccggagc cgccgccggt cgagttttcc gttgggcagc agcggcggtt
     5641 ccgccagggc gatgaacgcg gtcggcacca tcgcctcggg aacccgtcca cgcaggtggt
     5701 cccgcagttc ggcgaccgct tcctcgtgct gcccgggcgg gtcgcccacc caggagacga
     5761 acgcggtcag agtcatgccg tccgaagcct ccccggcccc ctcccgctgg gggacgacgg
     5821 cggcgtgccg tactcgcgga tggtcggtca gcgccgcctc cacctcgccc ggctcggtcc
     5881 gcacaccacg gaccttgacc tggtcgtcgg tccggttgag gaactccagc tccgcgccgg
     5941 gcagtcggcg ggcgcggtcc ccggtgcggt agagccgatc tccgggccgg ccggacaggt
     6001 gatccggcac gaaccgttcg gcggtctcgg ccgggcggcc ccggtagccc cacgccagct
     6061 gggcgccgcc gatgaacagc tcgcccgggg ttccgggtgg gaccggttgg cccagctcgt
     6121 ccagcaggta cagccgcaca ccggtgaccg ggtgcccgat cggcacggtc gtcccccggg
     6181 ctccggcctc cgcccgccac caggtggcgt cgacgcatgc ctcggtcggg ccgtagaggt
     6241 tgagcagcgc ggcctcggtg tggccgatca ccgcgtcggc cagccgctgc ggcagcgcct
     6301 caccgccgca gcacaccagc cgcagttccg ggcaccgggt gaaggtggcg ctctcggcca
     6361 gcacggcgag caggctcggc accacctgca gaacggtgac ggcccgctcc gtgaggaccg
     6421 tttccagggc ggcgatgtcc cggtccgccc cggccgggac ggtgacgacg gccgctccgc
     6481 agctcagcgg ggcgaagaac tcccacagcg cggcgtcgaa ggcgaccggt gtccgctgcg
     6541 ccacccggtc gccgggccgc agcccgaagg cctccaccgc ccaccgcacc tgctccacca
     6601 ccgcgctgtg cggcatcacc acgcccttgg gacgaccggt ggagccggag gtgtagagca
     6661 cgtaggcggg ggactccggc gacgaccggt ccagcggggg ccgccgctcc tcggggccgt
     6721 cgccccgccg gtcgaggatc atcgtgggcc cggtgaagtc gagccggtcc gccacgtccg
     6781 aacgggtcag cagaaggtcg gcgccggcgt cgccgagcgc gaactcgcag cggcgccgcg
     6841 gataccggac gtccaggggg aggaacgcgc agcccgcggc cagcaccgcg accagtgcga
     6901 cgaccaggtc cgccccgggg ggcacgtgca ccccgaccag gccctgcggc gccacgccgg
     6961 ccgtccggat ccggtcggcc agtacggtca cccgttcgta cagctcgttg taaccgacca
     7021 cagtgtcccc gtcgatgacc gcgggcgcgt ccggggtacg ggccgcctgc cgtgcgatga
     7081 gtccgtggag tgtggccggg tcttcggcgg cggcggacga ggagggcgtc gactcggcgg
     7141 gccggacgga cgccgggccg gggggcacgg aaccgagcag cggagcactg gtgcggggat
     7201 cgccttcgac gtcggcggtg atctcggtca gcgcccgcag gtagtagccg aggatctcgg
     7261 ccgggtcgcc gccgtgccgg aagagccgga gggtcatgcc gccggtctcg gcggcgtcct
     7321 ccacggtgag ggtcagcggc gcgacgggag actcggtgta ggtgtgctcg accgcgtcca
     7381 gcagttcgcc gcccggcggt cgatcggcgg ccggcatctc gcagtactcg aacagcgcac
     7441 ccgggaccag gcccgtctcg acgagttcgg ccaccgggaa ggaccggtac ggccggtggg
     7501 ccgccagtgc cgcgtccgtc cgctccacga gcgaggccca ggtcgggaca tcgcagcaca
     7561 tcgagaccgg cagcagggag cggaagtccc ccagggaccc tccgtcgacg cccgcgggcc
     7621 cgcgcgcgtc atcgagcagc cacgtccccg ccgtggcggt gccgccgatc agggcgagta
     7681 cacgcaggta ggcggccagc agcaccgcgt cccgggaggt ccccgcccgc tgggcggtcc
     7741 gccccagccg ggtcgccaga tcggagggca gcgccgccac cgcgggagcg ccccgcgcgg
     7801 acgccgcgtc gggtgatcgc catgccaggc cgtccgcgac ccgttccagc gttcgccgcc
     7861 agtacccggt cgcctcgggc gtgacggcgc cccactccgc ggcgaccatg tcgcgcatcc
     7921 cggtcaccgg tggcgcatcc gcggacggcc ggccacggag ttctgccgcg taaccgcgaa
     7981 gcagcgcggt ggtgagcagc gcactgctgc gcctgtcgag cagtggcccg gcgagccgga
     8041 gggagaccgt cacccggcca ccggacgttc gtcgcaccgt gcagcgcgaa gcggcgggca
     8101 ggccgagcgg gccggtcggc agttcggcga cctcgccgcc atcggtcccc gtccgcggcc
     8161 ggccggcgag ggcgggctcg gcggggtccg tggtcggggc cggatgcacc aggtgcaccg
     8221 gtcccccgga cggcggcagg tggaccgtac tgcgcagtac gggatggcgc ccgaccagac
     8281 cggcgagcgc gcggacgagc gcgggccggt cgcacgggcc gtcgaacgcg acgctcacct
     8341 cgctcgcccg gccgggatcg gccagcagcg ccgcctgctg ccaggcggtg agcggaaaga
     8401 cgtccgcgat ccgccccggt cccgcggcgg tcgcgtcgcg gtgcaccacc ggcccctgcg
     8461 tcatcatcac ggttctccca tcggctcgcc gcagcctcag ccctgtccct gcagagctcg
     8521 cagccggttc acgcttgagg tgtccagcgc ctgccgcacc tgtgcggaca cgttcacgtc
     8581 accgtccgcg gtggcgaaga ccaggccgtc cggctcggcg gccaggcgcc gcacgaggtc
     8641 gaggtactcg tcggcgaact ggccgacgaa cgccggttcg aacagatcgg ccgagtagtg
     8701 gaacatgcag tgcacaccgc cctcccattc gtagagctcg gcgaccaggt cgaagcgggc
     8761 cacttcgtga tcggtctcga acagggtcgc ctccacctcc ccgaaccgca gaggcgcgaa
     8821 cggcgcgttc tggaagttga acgccacctg caccagcggg acgcggtccg tggcgcggtc
     8881 cggtccgagc tcgctgacca gccgctcgaa cggcaggtcc tcatgggcga gggcgcccag
     8941 gtgcacccgc cggacatgct gcagaagccg gcggaacgtc ggttctccgg aaaggtcgag
     9001 acgcaccggg agggtgttga cgaagaaccc gacgaggttc tccagatccg gatgggagcg
     9061 gcccgccacc ggcaccccga tgacgaagtc gcgccggccg gcacggcggg cgaccagcac
     9121 ggcgaacgcc gcgaacagca ccatgaacag cgtgccgccc tcctgccggg ccagatcgcg
     9181 cacgatccgg aggacgtcgg gcgtgaggtc gacatcgcac cggccgcccc ggtgggaccg
     9241 ttccgcgggc cgcggccgcc cgggctggag ttcgagcatc tccggcgcgt ccctgagccg
     9301 cccgacccag tacttcagca gttcgtcgag cggctcgccg gtcagccgcc gccgctgcca
     9361 tgccgcgaag tcggcgtact gcgccgacag cggggccagc gtcccctcgc gtccgtcggc
     9421 gaacctctga tagagctcgc ccagatcgcg gaagagcacg ccggtcgacc agccgtcgat
     9481 cgccaggtgg tgcaggcaga tgccgatcac gtgatcgtcg tcgtccagcc ggacgacccg
     9541 gaccttgaac agcggggcga ccgacaggtc gaagcgcccg gcgctgtcct cctccagcat
     9601 cgtgcgcgct ctgctctcgg cctccggcag cggaagggac gagaggtcgc tgaaggcgag
     9661 cggcggttcc agcgacccgt ggacgacctg gacgggacgt ccgtccctct cgtccaggcg
     9721 ggtccgcagc aactcgtgcc gctccatgac ggcggcgagc gcggcccgga acgccggcac
     9781 gtccacgggt ccgcgtagcc ggcagggcag caggatgttg tcgtggcgcg ccgcccctcc
     9841 gagccggtcc atgatccaca ggcgctcctg ggcgaaggac gcgggaatcg gcccggtccg
     9901 atcgcacctc ggaatcgccc gttccggctc cagcgtggct ccggagcgca gcgccgccat
     9961 cacggcgtgc gccgtgccga tcaccgtggg gtccccgaac aggtcgttga gggtgaagtc
    10021 cacgcccagg gccgagcgga tccgcgacac cagcttgatc gcgaggagcg agtgaccccc
    10081 gaggtcgaag aagtcctcgt cgacgccggg ggcgcggtcg aagacctggg cccagatgcc
    10141 cgtcaggacc tcgatcatca cggcggcggg cgacgccgcg ggcacggcct cccgcccgcc
    10201 gtcctcctcc ggtgccggca gggcggccac gtccggctgc ccgtcccggg ccgtcggcat
    10261 ggcggcgagc ggtacgaacg ccgacggcac cagccgtgcc ggcagccgga gcatgaggaa
    10321 ctcctccagc tccgcggcgt ccggcatgtc ctgcacggac tcgccggccg gcacgacata
    10381 cgcggtgagc cgttgttcac cggacggccc cgttcccacg gtcaccgccg cgtcccgcac
    10441 acccggatgc ccggccagca ccgcctccac cgcccactgc cgggcgcctg cgttcctcgc
    10501 gggcacgggg ccgtcggcgt ctgccgcgga cggcagcacc cgcgcatggc cccggcggcg
    10561 cgccacgagc ggcgccgcga cgagctcccc cgtgcctgcg tgccagaacg aactctgcgg
    10621 caccggatgc gggaaccggt actcctccac cagatccgca cctgtcccct gggtcagctc
    10681 aagccgcgac gccgtcggca ccgggccggg cacgaagacg aggcgcaggg aacggcaccg
    10741 cccgagggcg gatgccaccg agcccggtgg cgagccgggg atgacggcga cggtggcctc
    10801 gttctcgacg aggatctctt cgaggacggc cggggacacc cccgcggacg gccgggcggc
    10861 gcgcggcggg aggaccagcg ccgcaccgga ggacatcgtc cagaagatgt cgcgcaccga
    10921 ctccgccgaa ccgggcgaac gcagatgtgc gacgcggtca tcggcggaca gggggaagtg
    10981 ctcgcccatc cagtgcagca gccctgccag cgcgtcgtac ctgatcaggg aggccgcggg
    11041 ctcctgcgcg tcatgcccga gcaccgccca gcgcgtcgcg gatggggcgt ccgccgcgct
    11101 ccccccggga gtgggccccg cgcccgggtg ctccgccgcc tcccgctccc ccagccgcag
    11161 gagccgcaga tcaccgccca ccgtcacctg gtcggtcgcg gccggcgagt cggcgtggga
    11221 gccgtcgcag agcacgaccg tggcaccggc ggcggccacc gcggcgccga tccgctcccc
    11281 gccgtcgtcc ggatccagcg gcaggatcgt gcccccggcc ttcaccacgg ccagcaggcc
    11341 caccgccagt tccgcggacg ggcccagcat gacggcgacg gggcccgctc cggagcggcg
    11401 cagctcgtcg gcgacgcgtt cggcccggcg gtccagttct ccgtacgtca gcgtgagatc
    11461 gccacagatg atcgccggcg cgtccggggt gcgcaggcac tggccggtca gccggtcgag
    11521 ggaccgtcca ggggacggaa cgccggtcgt ggtgaccccg tcgtccgccg cggcccgccc
    11581 gacgggttcc ggccatcccg gcagctcgcc gaggcggcgt tcgggatcgg tggcggcgat
    11641 ggtgaggatc tccaccacca ggtcgcggac acgctcggcc gtgtcccgcc ggaagcgcac
    11701 cggatcgtag ccgagggcca tccgcaaccg ccgctggtcg ggcacgaccg tcaggtgcag
    11761 ggggtagtgc ggctgctgga tgacccgcag gtcggcgacc cggaccgtcc ccccgtcggt
    11821 ccagctcggc cgcaccggat agttgatgta gacgaccagg ctctcgaaca gcgcggtgcc
    11881 gcgcggtacc tcgctccatc gctggacgtg cgccaggggg ctgtagtcgt actcccggcc
    11941 gtcggccagc tgcgcctgga gcccggtcag ccagtcggcg agcgaggtgt ccccggcgac
    12001 ccgggcccgg accggaagga cgttgatgaa cagcccgacc atgtcgtcca cgccggcgaa
    12061 ctcgggtggg cggccggaga ccaccgagcc gaacacgacg tcttcccgcc cgctgtaccg
    12121 gctgagcgtc aacgcccacg ccgcctggac caccgtgccc agcgtcagcc ggcgcgtccg
    12181 ggccagagcc tccagccctg tgaacacctc cgggggcagc gtcgcgtgga cctcgccgaa
    12241 ctccggcccg ttcctgaccg gggggtcgac ggcttctccg ccgatcggag tgggctcggt
    12301 gaatccggcg aggcgctcgc tccagaagct ctcggctctc ccgagatcct gccgctgggt
    12361 ccacgcgacg tactcccaga acggtctcgg tgccccccgc tcgggcagcc gtccggcggc
    12421 gagctcccgg taccagccga acacgtcgtc gagcacgaga taggtcgacc atccgtcgag
    12481 cagcagatgg tggtaggacc agaccagcca ccacgcctca tcggcgaccc ggaccacggc
    12541 caggcgcatc agcggagccc gcccgagttc gaagggacgg gtcctgtcct cgtcgagcat
    12601 ggcgttcagc cgctgctcga tctcctccgc gggcgtgccc cgccagtccg actcctgcca
    12661 ttcgggctcg gcgtcatcgc tcaccacctg caccggcagg tccagccgct cgtagtggaa
    12721 cgaggtgcgc aggatcgggt gccggcggat gacggcgcgc caggactccc gcagcagcga
    12781 cgggctgagg gcgccctcca ggcgaaggca gagctggtag atcgtctcac cggagtcctg
    12841 cttgcgcagc gcctcgaaga acatcccgtc ctgcaacggc gtcagccggc agatccgctc
    12901 gatttggtcg ggacgcatct gtaacccacc ttcgggggac tgggagatcg agtggcgatc
    12961 gaccgacacg tcggctcgcg ggccgccggg ctcagccggc gaccggttcg ggcgcgggtt
    13021 ccaccgtggg ccggcagtcg gccagactca cctgttcgcc catcgcgacg aggatcttcc
    13081 gatcgccgcg gaaggcctcg cggccatggc aggacaggat gttgtcgacc agcagcaggt
    13141 cgcccggccg ccacggctca cggcgctggg cgccgtcgta cgcggcgttc agcgcggcga
    13201 tgtcctcggc gtcgatgggg ctcccatcgc cgtagagagt gtcgaagggc agcccgtccg
    13261 gtccgtagct ggtcaggaga acatcccgga tgtcggggtc gagggagtgc tggttccaga
    13321 aggcgatgtg gttgaaccac acctcctcgc ccgtccccgg atgatggatg gtcgtcgccc
    13381 gccgctgcgt cgtcgccagg ccgccgtcgg gcagccatct gtatccgatg gagctgcgac
    13441 ggcagtagtc ctccaccctg gcgcggtcgg acgttccgaa ggcggtcgac cacggcaggg
    13501 agacatgttc gcggtagttg cgcgcgagta cccaccccag ccggcggaag cggtcggcca
    13561 gctccgcggg gacccgtgcg agcacctccc gggtgtcggc cacggtggtg gccccgccct
    13621 cttccggtgc caccaggcag ccgaaaagca ggattccggg gaagtccagg gtgtagctgt
    13681 tctcgttgtg cagccggatc acctgcgcgc tgggcaggtc ggtggacgac agcaccccct
    13741 ccccgtagtc gctgcgcggt gtcgccttct cccggtagct caccctctgg tcgagcagaa
    13801 cgtcgcgcgc cccggcgaag tcgtggacgc tctcgatggg cagaccccga accagcagac
    13861 atccgtatcg ggccagcgcc gcgccgaagg caccgcgccg ctcggtcaac cactcgcggg
    13921 cggtcgccat ggacgtggtc tcgcccgcct gcgcgatcgg cggcccggac tctccgacgg
    13981 acaagcccag ttcggcgatg gcctggtcgt tcaccgtcac gtccatccct ccttccccgg
    14041 tccgcgcgcc gccgccggac cgatcggccc cgacggcgag cagtccgcca tccgccgcgg
    14101 ctctcccatg gcgaccagca cccggcggtc cccggtgaac ggctcacgcc catggctgca
    14161 caggaggttg tcgaccagca ccagatcgcc ccgccgccag ctctcgcgga ccatcacctc
    14221 gtcgaaggcc ctgttgatga cggccacgtc cgcgggatcg atcggcgagc cgtcgccgta
    14281 gtaggtgttc tgcggtaacc cgtccggacc gcatgcggcc accaggatct cccgggtctc
    14341 gggatcgtga gtccactcgt tgaacaccgc gacgtggttg aaccagctct cttcacccgt
    14401 cgacggatgc cggaccgtgg ccgagcggac tccgctggtg cgcagccggt cgtccggcag
    14461 ccactcatag ctcagctggt tctggtcgca gtacgactcg acggccgcgc ggtccgccgt
    14521 gccgaaggcc tgctgccacg gcattcccac atgcttctgg aaattccgga cgatcatcca
    14581 gccgcggcgc ctgaaccgtt cgaccagatc ggcgggcaat gcggccagta cccggcgggt
    14641 gtcgcccagg gtggtggcac cgccccgctc gggcggaacc aggcagcaga acagcaggat
    14701 ccccgggaac accacgctgt agctgtcctc gcagtgcaac cggatgcgct gcaccggcgg
    14761 cagatcggtc gccgagaaga tgccgttccc gtagccggtt cgcggggtcg tctcctccct
    14821 gggaacttcc aggtggtctt cgagaagcac atcccgtgcg gcggcgaaat gctcagggga
    14881 cgccaacggc agtccacgga tcatcaggct tccatggcgg cgcaactcgg tcagaaccct
    14941 ctcccggttg tccgccagcc atgcctgcgc ggaagccgcg tcggcgacgc cgtccacccg
    15001 cacgagggtc ggcgccccgt cggccgcggc ggcatccgca ccgtcggacg agtcccgtcc
    15061 ggcgtgacga accatcggtc atcctccgat cgggccggtc ggcgcgacgg cccgcttccc
    15121 cagcacgaag cgggtgatgg catcgacgct catgaaattc gcaatgtcca gatcgtcgcc
    15181 ggagaccgcg agatcgaagg tgcgctcgac ccaggtgagg atctgcacgg cgaacaggga
    15241 gctgacgaag ccggtggcga agatgtcgac atcgtcggcg atcgacgctc ccccggtgtg
    15301 ctgggacacg aattcccgca ccatggcgat cacccgccca ccgtcgggtt cccgcgagtt
    15361 cccgccgagt tcaccgtcca tgggtccctg ccctcctcca cgttggtacg agccggcgtc
    15421 agtcgtggtc atagacatgg aaacctcgtc cggtcttccg tccgaggtga ccggcgtcca
    15481 catacctgcg aagcagcggg cacggccggt acttcggatc ctggaactcc tccagcagga
    15541 cctccagcga atagagaacg gtgtcgagac cgatgaggtc ggcggtctcc atgggcccca
    15601 tccggtgtcc gaagcatttc ttgaagagcc ggtcgatgtc cttgggcgag gaaacctgct
    15661 cgtgcagcag gaatatcgcc tcattgatgg tgagcatgag cacgcggttg gtcacgaaac
    15721 cggaggagtc gccgacgagc acagtctcct tgccgatgtc ggccagcagc ccccgggaca
    15781 gctcaagggt cgcgtcgctc gtgtggacgc ctcgtatgat ctcgacgaga ggcatgaccg
    15841 gaaccgggtt catgaaatga ttgccgatca ccttgtccgg tcggcccgtg caccctgcca
    15901 gcctggtgat gggaatggcc gacgtgttga ccgcgagtac gcactccggc ccgcagacgc
    15961 ggtccaaact ccgatagagg tctttcttga ccgcccactt ctcggtcacg ttctccacca
    16021 cgtagtcggc gccgcgaagg tcgcccaggt cggtggtcgg cgtgatcagt gcgaggatct
    16081 cgtcgggcgt gcgctttgcg ggccggccga ccaccacggg cagcagccgg gcgtttcccg
    16141 cgatcgtctc tctggcggtc ttcagcgccg cctcggagat gtcgatcagg gtgaccgggt
    16201 accccgcctc ggcgaaggca tgggcgactc cggtgccgat ggtgccggcg ccgacgactc
    16261 cgaccgtctg aatcatcgat cgactcccct accgtgcggg cgaccgcgtt cgtcgccgcg
    16321 gaactcttcc ggccagccgc tttcatcgag cccgtgctgg cagacgaagg cgtatgccag
    16381 ccgctccagg ccgaacccca cacatccggt ccagaccggt ccgcggtcac ggccggtgat
    16441 gtcgaacgcc gtcccgaagt gctgctcgtg gaaattgaac gacccgacgg cgacggtcgc
    16501 atccggggcg atgtccagac gcagctcgta cttcagttcg agaagccgtt gcgcggatat
    16561 ccgcgacgcc ccgtcggcgg cgcagaagaa cgggtccgtg gccacctcgc agcgtccgga
    16621 gaggccgagc cgttcgacca gttcgatcgc tcgtcgcagg aagcgttccc ggccgtccag
    16681 gacctgctcg cgctccccca tgaacacgat ctcgcggatc gtgaagtccc acagccgctc
    16741 cagcgaggtg tggtagcggc cctcataccg gaacgacttt ccgcgagcgg tgaccaccgt
    16801 ggacggcgac gagagccgtt tccccgcgta ctgatggaag gtgtgatagc acatggtcgg
    16861 cggtaggcag tagtccgcgt tgcggcaatg ggcgagcatc gcctcgccga cgtgtccctc
    16921 gtcgtggtcc cgctcggtga acttccggta gacgtccagg tcgccccgca gccgggtggc
    16981 gagcatgacg tgctggggaa acgcactgaa gtatccgctg cgctgcaagg ccccggtggg
    17041 aacgagcgtg ggatagcgga actcggtggc gccgagctcg gtgacggcga tctcccgcag
    17101 catgccgtcg aaacggtcca tgagcgtcag cacgggctca ccgaccgcga tctgcccctc
    17161 ccccgcctcg aaggccgcgc cccggtccgc cagcgcctcg aagatgtcgg gccgcgtgtc
    17221 cgttgtgcgg gtcgagcgcc agaccacctt ggggggacgg gccagctggc cgaggacgtc
    17281 catgcggacc atgcgccgga gtttgcggga gagcgcggcg gtcggctcgg ccgtgccggt
    17341 ccgcagcagc accgcgtcca cggcgtcgcc ctgaccgcgc agcagccgga agctcgcgat
    17401 gtcctcggag acgaagaaga tccgcctggc cagctcggtg gcgagctcgg agggtaccgg
    17461 gcggggcagc cggaccgtgt gctcggtcgc cctccccccg ggccgaccgt tcctgctcgg
    17521 ccgggtgctc acggcgcacc cggcaggccg agcaggctcg cgatgatcga ccgctggatc
    17581 tgcgacgtac cgccatagat cgttccggcg agcgcgtcgc gcagctctcg ttccatcccg
    17641 ccctcggtga ggtagccgcg ggcgccatgg atctggaccg cctccagggc ggtttcgagc
    17701 agaccctcgc tgacgacgag cttgaggatc gacgactcca gcatggccag ccggccctcc
    17761 cgcttcagcc agccgaactt gtacagcatc aactgcgcga gttcgaggcg tattcgcatg
    17821 tcggccagcg tgtgggacac ggcctgaaac gaaccgatcg gccggccgaa ctgctcacgc
    17881 tttgcagcgt ggtcgacaca ggtctccagc agccgccgca atgtcccgac gccgctggcg
    17941 aaaaggaaac cgcgctccca ttcgatcgtc gacgtgaata tctggtgccc ggcgccctcc
    18001 cggcccagca ggtgctcctc gtcgagccgt acgtccgaga attggatctc tcccatgggg
    18061 gcgccgcgca ggccggcctt ttccagctcg cgcgcgatcc gcactcctgg cgcatcggca
    18121 cgtacgagga acgccgacag cccgcgctcg ggcgcctccg attcgctggt ccgggcgaag
    18181 gtgacgaaga ggtcggcaca cgatccgttg ctgatgaagg tcttggtccc gttcagcacc
    18241 cagcccgagc cgctccggtg agcggtggtg gccagcgcca gcatgtccga gcccgcctgc
    18301 ggctcggtca gggcgtgcgc gccgatgacg gtgcccttgc ataattccgg tagccaccgg
    18361 gccttctggt gttcggtgcc gtacttgacc aggtagatcg cgcaggccca gacgtgattg
    18421 ttgatcgcga agagcaggcc gttgttcgaa catccgtagc cgagcgcctc gaaggccagc
    18481 gccgaggtga gcgggtcgaa cccggagccg ccgtggtcac ggggcaccgg ccagcccagt
    18541 gctccgaagt cggcggcctt ctgccagcca tcggtgtcga ggcttcccga cctgtcggag
    18601 tcgccggtgc gaccgcccag ctcttggcgt gcaaaacgaa ctgtttctgc gcacagctct
    18661 cgctgccacg ggcttatcgc aaaatccacg cactacctcc tgggcatggg cggccatcgg
    18721 cacctggcga acggcgttgc gttgtgccgc cgggcgaccc acatgcagag catggccgct
    18781 caccgcgtcc cagggcatgt cacgcaaacg cgggacttgc ccgcctgtcc cgcctggggc
    18841 atctgttgaa acggccgtag gcgtgtactc cagaactgat gggcgtcttc actaaggaga
    18901 aagcgtgctg ctacggatgg ctacccccgc agatctgagc gcgctgctgg gcatatacga
    18961 cagcaccctg cgctggctgg ccgagcgcgg cacggaccaa tggcaggagc cccgcctgga
    19021 acccgagatg atgaaggcgg ccatcctggc gtccatccac caccggcaga cctggtgcgc
    19081 gatcgacgaa cagggcggac atgccggcct ggtgacgatc aaaccgcaca ccccgccggg
    19141 cctttggcgg ccggaggagg agagcgagcc ccaccgttac ctctacctgg cgctcgtgtc
    19201 cagagagaac accggcgtcg ggctcggggc cgacctggtg gactgggccg tcacccgggc
    19261 ggccaaggcc ggagcgcgct gggctcgcgg tgacgtgtgg accgccaaca agcccctcca
    19321 ggagtactac ctgcggcatg gatggcaatt ggtgcgctat gtccatcggc cggaccagcc
    19381 gtcgggtgcg ctgatccaac ggcccgccgt gccatgcgag actccacgcc tcgtcgaggt
    19441 gcccgagacg tgaagaagcc cgattgcggg acgcaccgct gaaaaccgct tctaccaggc
    19501 ccgcaatgcc gcttcgctcc gcgatggggc gtctgcggcc cggtggcgag gccgcgggat
    19561 ggccaatacc ggccgaatga cttccgctcg aatgtgatcg gtcatcgcgt ggtcacgccc
    19621 tggagaccgg gctgtcaagg gaccgtcccg ccggccggcc ctgcacggaa gcgcggctac
    19681 tccggggcgc gactcgggcg acatttaagg aacggtccaa aatagcggcc gtcttttgtc
    19741 ttagcacgtt ccataacgcc tctgagctgc gaagacagga aacggcgggc cagcctcatg
    19801 caccgggtgg agcacccgat aagcgctccc gccaccaagg ccgatccgcc gttccccgcg
    19861 cgcccctgcc gacggatgac aagtccgccg cgttcaagag gggcttacgc gcttgacaat
    19921 ataacactta ccacgggccg atcgccctgt taccatccga ttgaactcaa agaagagccc
    19981 gttccggctc tctcagcgag ttgcactgtt caccaaggtg caaccaggga gagccgggac
    20041 tgacaacccg ggacttcctg gtgcacccat gcaccgaaag gggagtcccc gaatggactt
    20101 caccaaacca aaagcgggcg gcgagctgga caagtccagc gaagccgctc cgccccaggg
    20161 caagctcgcc gccctcgtgg tggcggcact cgtgatcggc gagaccggcg tcatcctcca
    20221 gctcttcttc aacgtgatca aggaggaggg cgccatcatg acctccttcc tgcagaccgt
    20281 tgtggggacg gcgctgctgt ggtgcgtggt ccggccgaat ctcaaggccg ggtggccgct
    20341 gtggtggcgt tcgctcgcca tcggcggttc gagcgtgctc agcctcgtcg ctgcgaggga
    20401 ggccatgacc ctcgtcccct acgggacgat cacgtgcctg gcgttcgtct tcggcccgat
    20461 ggccgccgcg agcttcagga tcatccgcgc caggatgatg cggacgctca tatggccgct
    20521 cctggccgca gcgtccgtgt tcctgctggt cgacggactc gggtccggcg acctcgtggg
    20581 cttcgggctc atcgcgctgg tggcgctcgc ctaccacgtg tacgcgacga ccacctccgg
    20641 cctccagagg gacgaggtca acacggtggc gaccttggca aggctgccca ccgtgctcct
    20701 cctcacgggg atgctcttct ccgctgagga gcccgacgcg ctgctccacg tcagtgggga
    20761 agcctggtgg gtctgctcgg tctccggcgc cgtcggcgtc gtggccctgc tgatgatcaa
    20821 cgcggcatgg aagcgcggcc tcacggtcac gacccacgcc agcgtgatgc ccgccgacaa
    20881 cgggctcgca atggtcgacg gcatgatcgc cggccaattc ccgtccctgg ccaactggct
    20941 cggggccggg ctggtcatca tctcggaggt gggcgccacg cgcgcccgga tcccggaccg
    21001 gaagcagccg ccgaagttct ccatgtggct cgacggcctt ccggccaggt tcaaaggctg
    21061 acccgaacgc gtggacacgc atcgggtaac gaggtgaggc cctagggccg atccgctagc
    21121 cgcggcgggg agggatcacc ctccccgccg tcttttgtgc aacccgcccg gccccggtgc
    21181 gacaggcggc ccctccgaca gggccggaac gcgtccggtc aggcggtcac cagggtctcg
    21241 acgccggcgg ggaggctgcc ggccagggcg gcctcgacga ggaacgtctg gagcgtctcc
    21301 tggaatgctc gggccgcgtg ggtgagctcg acgtccttgc ggtgggcgag cgcgatggtg
    21361 cggagcaggc cggggccgtg gcggccgcgg cgggtctcct cgtccgccag gacgagcggg
    21421 gttccacgca ggccggggcg tccggccagc accatgctgg ggaccaccgc gatgccgagc
    21481 ccgacctcca cgaagcgcag gacggcgtcc atctcgccgc cctcgaccgc gaacctcggc
    21541 tcgaacccgg cggccctgca cgcgctgatg gtcgcctcgc gcaggtcgta tccggcacgg
    21601 aacatcacca gcgggcggtt ctgcaggtcc tcgatgcgca ggtaagagcg gcgcggcagc
    21661 tgggcggccc tcggggagcg ctccggggcg tccggcccgg gtcccgccgg ggaggccacc
    21721 accaggtact cgcgcaggat cggtgtcgtg tccagtggcg ggtcgccgtg caggggaagg
    21781 atgaccaggg ccatgtccag cgagccgcgc gtcagctccc ggacgaggtc gcgggagcct
    21841 ccttcctcga cgatgagctg gatccccgga taggtgtcgt ggaagcggcg aaggacgtcc
    21901 gccagcaggc ccgcgcacag ggacggagtc gcgccgagcc gtacccgccc gcgcttgagg
    21961 ccgaccagct cctggacctc caggcgggcc gtgtcgacat cggccagtat gcgctttgcc
    22021 agagggagca gcgcctcacc cgcgggagtg agggtgatgt tgccccgcgc gcggctgaac
    22081 agcgacacgt tcagctcgtt ctccagcgcg cggatctgct tggacagcga aggctgcgcg
    22141 acgcgcagca gctcggcggc ctgcgtgaaa tggcgtacct cggcgaccgc gacgaagtag
    22201 gcgagctgct gcagctgcat cctgcacagg gtacgggtca ccgtccctca cgccctccac
    22261 gggggcggtg tccctccggg gacgcccccg gcaactccgc cggcccactc cttctcggcg
    22321 ctcggtcgcg ggtcagcgcg cgtggcggcg tagggcctgg aggtcgtgga cgatgaggcg
    22381 gcggcggccc gtctctatcc agccgtgccg gcgcagcgtg cgcagtgcct tgctgaccgc
    22441 ctcgcgggac gcgcccaccc agcccgccag ctcttcctgc gacaggttca gcgtgatctg
    22501 gacgctgtcg ccgcccgccg cgcccgtccg gcggtcgtag ggcacgccga accgctccgc
    22561 cagctcgacg aggcgctgcg cgacccgccc cgtcgcgtcg aacatgccga actcgacgcg
    22621 cttgcggtcg gcgtcgcgcc agcgctggca cagcatccgc atgatgagga cggagacgcg
    22681 gccgtgcacc tgtaagaacg ccatgaactc gtcggccgtg accgcgagcg cccccaccgg
    22741 ttcgagcgcg atgaccgtcg ccgagcgggg cagcccgtcg atcgcggcga cctcgccgag
    22801 cagcgccccc ggaccgcgca ccgccaggat ggtctcgccg ccgaactccc ggtaggagca
    22861 cgccttgacc cggccccgca acaggaccgc cacccagccg gggtcctccc cctcgacgaa
    22921 gagggtctcc cctcggtcga agtcgcggac gcggccgcgg gccgccagct cctcgcgttc
    22981 caccggggtg agatcgccga ggaacgaacc ttcgagggcg ctcatgccca caacgctaaa
    23041 gggcctggag cgttcccgcc tcccgggaaa gaatcacggt tcaatcacgc gttgtgtgca
    23101 cttatcccta ctcgaacatt cgagggtgcg ccagtgttgg acgcggcgtg cacggccgga
    23161 gtcgtcccgg cgtccacggc gttcacgggg aacggcggaa cggcgggcgg cgggccgggg
    23221 gcgcgccgcc cgccgggcca cggagcgtcg cctgccagaa cggcgtcccg tgacgggaag
    23281 cggcggaaac gcgaacgccc cccgtcgcgc ggggcgacgg ggggcgttcg cgaaaagccg
    23341 tgcgggcggg tcaggcggac ggggtgtcct cgcccttgcg cacgatgccg agcttgctgc
    23401 cgagccacac cagcgggtcg tacttgcggc cgacgacccg ttccttcatc gggatcagcg
    23461 cgttgtcggt gatcttgatg tgctccgggc agacctcggt gcagcacttg gtgatgttgc
    23521 agaagccgag accgtggtcg tcctgggcga tgttgcgccg gtcggcctgg tccgccgggt
    23581 gcatctccag ctccgcgatc cgcatcaggt agcgcgggcc cgcgtactcg ggcttgttct
    23641 cctcgtggtc acggatgacg tggcacacgt tctggcacag gaagcactcg atgcacttgc
    23701 ggaactcctg cgagcgctcg acgtccacct gctgcatgcg cagctcgccc ggcttggcgt
    23761 cgcccgggtc gaacgagggg acctcccgcg ccttctggta gttgtacgac acgtccgtga
    23821 ccaggtcgcg gatgaccggg aacgtgcgga ccggggtgac ggtgatcgtc tcctccgggt
    23881 cgaaggtcga catccgggtc atgcacagca gccgcggcat gccgttgatc tccgcggagc
    23941 acgagccgca cttgccggcc ttgcagttcc accggacggc gaggtcgggt gcctgcgtgg
    24001 cctgcagccg gtggatgatg tcgaggacga cctcgccctc gttcacctcg acggtgtagt
    24061 cggtgagctc gcccgtgccg tcgtcgccgc gccagacctt gaacttcgcc tcgtagctca
    24121 tcggccgtcc tcctcgttct ccgcggcgtc ggcggcggcc gcgtccggct ccggcgcgtc
    24181 cttcgcatcg ccggcggacg cctgctcggc gggggccgtc ggcagctcct cggcggtcag
    24241 gtacttcttc agctcgtcgt tgtcgaacag ttcgagcagg tccgtccgca tcggcgtgag
    24301 cggctggcgc ctcagctcga cgtgcgggga cgacgggtcg ccggccagcg agcagaccag
    24361 gttgatcttc cgccactccg ccgacatgcc cgggtagtcg tcgcgggtgt ggccgccgcg
    24421 gctctcctgg cgctccagcg ccgccttcgc gaccgcctcg gacaccagca gcatgttgcg
    24481 caggtccagc gcgaggtgcc agcccgggtg gtagccgcgc ccgtcgccga ccgcgacggg
    24541 atcgacgctg acgttcgcga cccgctcgcg gagcttgccg agcgacgcga tcgcctgctg
    24601 cagctcctct tccttgcgga tgatgccgac cagctcgttc atcgtctgct gcagctcggc
    24661 gtggacggcg taggggttct cgccgccctc ccgctcgaac ggggccatcg cctcggccgt
    24721 cgccgcctcg atctcggcgt cggggacggc gggacgcgcg gggagggcgt ccacgtactc
    24781 cgacgctccc agcccggcgc ggcggccgaa caccaggagg tccgacagcg agttgccgcc
    24841 gagccggttc gagccgtgca tgccgccgga gacctcaccc gccgcgaaca ggccgggcac
    24901 cttggcggcg ccggtgtcgg gctcgacctc caccccgccc atcacgtagt ggcaggtggg
    24961 gccgacctcc atcggctcct tggtgatgtc gacgtccgcc agctccttga actggtggta
    25021 catcgacggc agccgcttga cgatctcggc ggcgccgccc ggcatccggt cgacgacggt
    25081 gaggaagacc ccgccgtgcg gcgatccccg tcccgccttg acctccgagt tgatcgcgcg
    25141 cgccacctcg tcgcgcggca gcagctcagg ggggcgcttg ttgttgtcgg ggtcgtcgta
    25201 ccagcggtcg ccctcctcct cggtggtggc gtactggttc ttgaagacct cggggatgta
    25261 gtcgaacatg aaccgcttgc cctcggagtt gcgcagcacg ccgcggtcgc cgcgcaccga
    25321 ctccgtcacg aggatgccct tgacggacgg cggccagacc atccccgtgg ggtggaactg
    25381 gacgaactcc atgttcagca gcgatccgcc cgagagcagg gccagcgcgt gcccgtcccc
    25441 ggtgtactcc caggagttgg acgtgacctt gaacgccttg ccgatgccgc cggtcgccag
    25501 caccaccgcg ggggcctcga acacgacgaa cctgccggtc tcccggacat agccgaacgc
    25561 gccgcagatc ctgccgtcgg gatccttcag cagccgcgtg accgtcgtct cggaccagac
    25621 cttcagcctg gcctcgtagt cgccgtgctc ggcgtggtcc tcctgctgga gggcgacgat
    25681 cttctgctgg gcggtgcgga tcagctccag gcccgtccgg tcgccgacgt gcgccagccg
    25741 cgggtactcg tgcccgccga agttccgctg gctgatcttg ccgtccttgg tgcggtcgaa
    25801 cagcgcgccc cacagctcca gctcccagat gcgctccggg gcctccttgg cgtgcagctc
    25861 cgccatccgc cagctgttca tgaacttgcc gccgcgcatg gtgtcgcgga agtggaccat
    25921 ccagttgtcg ttggcgttga cgttgcccat cgccgcggcg gccccgccct cggccatcac
    25981 cgtgtgggcc ttgccgaaca gcgacttgga gatgatcgcg gtcttcttgc cctggaggcg
    26041 cgcctcgatc gccgcgcgca gcccggcgcc gcccgcgccg atcaccacga cgtcgtagag
    26101 gtgcctctcg atctcagtca tgattccttg gcctcagttg aagatgcgca ggtcggagat
    26161 ggtgttgctg gcgaccagcg cgacgtacag gtcggccacc accagcgagc ccagggtgat
    26221 cagggcgtac atcccgtggc gctggttgat cttggacacc cagccccaca tccggtagcg
    26281 gaaggggtgc ttggagaagt tcttcagccg gccgccgacc acatgccggc acgagtggca
    26341 cgacagcgtg tacagccaga gcaggaccac gttcgcgacc aggatgatcg tgccgagccc
    26401 gatgccgaac ccgccgtcct tgccgtggaa ggcgcggacc gcgtcccagg tgttgatgag
    26461 ggagatggcg aaggcggcga gccagaagta ccggtgcagg ttctggccga tcagggggaa
    26521 gcggcgctca ccggtgtact tgccgtgcgg ctcgcggacg gcgcacgcgg acggcgacgc
    26581 ccagaacgag cggtagtagg ccttgcggta gtagtagcac gtcagccgga agagcagcag
    26641 gaacggcagc gagatcgccg cgaaggggat ccagccgcgg gtggccgccg gcaggaaggt
    26701 cccgaactcc gccgcgtcgc ccgtgtgccc gtccaccgtg acgttgttgc agatctcgtt
    26761 caggcacggg gagtagaacg gcgtcaggta gtggaactcc gggacgtaga aggccgcgcc
    26821 ccagaaggcc cggacggtcg cgtacaccac ccatgccgtg aagatcacga aggtcgtgac
    26881 cggatacagg cgccagttgt ccttgcggag ggtgcgttcc ttgatctggg cgcgcgactt
    26941 ggccggcgcc tccacagtgg tcatcgatcg ctctcctgag ctcgggtcgt cgtgtccccg
    27001 taccacggtc cgcgcgcacc atgcggccgt cgcgccgcgg ccgacgacag ggcgtccccg
    27061 gccgggccgc gcgcggcggc cggagaccgt gccgcatgcg ggcggtgacg ccttgtgtgc
    27121 gcttccagcg aagcgaccct acgccacccg ccaggagctg tgacatacat aacaggcaga
    27181 cccgcatgtg accctgacca cagactttag cccgctcagc gccctttcac ggctcccggg
    27241 agccataacc agtcgttatg atcaaagtga atcgagacga gaccgctcgg gcatgaccgt
    27301 ccggtcgtcc ggcgtctgct tcagcaccgt ccgggcgaaa tgcgcctcgg cctcgctcgt
    27361 gcggccggtg ccgtacaccc gcagcacctc ggcgaggtcg gggaagcggt cggcgacgag
    27421 cccggcggcc gcttcgatct cggcggcgga cgcaacctca cgcagcaggg cctggacgag
    27481 ccgcgccggc tcggccgccg cgcgttccgc cgcgccttcg ggacccgccg gcacgggacc
    27541 ggtcggaaca cggccggaga ccgccccgcg catccccgac gtggtggccg cggactcccc
    27601 cttgatcccc tccaggcgcg cctggagccc ggcggcggtc agcgcgtcga agccgggccc
    27661 ggcgacgagg tcctcgaccg ccatcaggcg gtgcaggacg gccgggttgc tgatcttggc
    27721 gcgctggccc gacatgagct gggagagcat cggcgccgac agcccgagca cgccggcgag
    27781 ccccgactgc gacatcccga ggcggccgag cagcggccgg acgcggtcgc cgagcggctc
    27841 cccgtaccac tcggcctgca gcgcgcggtt ccgggcgatc gtgtcctcgg cgacgctcac
    27901 ccgcagaccc ccttgacgat tcacagatgc aaacgataga ttcgcgaccg cacatggaac
    27961 tgcggcgcat gacgccatgg tgccacgaac aacagcattt gcatatgtga cagatcgaaa
    28021 ggaacgacga tgggtctggc acatcgcctg gccgccgcca ccgcgacggc cctgctcctc
    28081 accggcggcc tggccggctg ctcgctgccc gggacgggct cgtcctcgaa ctccccctcg
    28141 tccccgtccg gcggtaagaa ggccgagggt tcggtgggca gggcgagctt cgacaacgcc
    28201 tccaagccac tggtgaaggg caccttcgac agccccctgg cgcagggcgc caagatcgac
    28261 atcgccgtca tgggcctcaa gacgaggggg aggctggcca ccctcaccat gcagctcacc
    28321 ccgcacgtcc cccccggcgg gccgacgcgc atcaacgcct acggcctcaa cggcgaacac
    28381 ggcctcggca cctcgctgat cgacccggtc aacctcaagc ggtacgtcgt ggtgaaggac
    28441 accggcggca aggaactgga gaccgacgac atcttcaccc acatgaccaa cgaccaggtc
    28501 actccgttct acttcacctt cgccgccccg cccgagaacg tgaagaccgt cgacgtgcag
    28561 atcggcacgt ggcccacgtt ccgcgacatc ccggtcgaac ggtgagccgc ctgcgccggc
    28621 cggccgtcct cgcgggggtc ctggccctcg tgctcgccgt cccggccgtg gcgggagccg
    28681 accccggagt gccggaccag aacctggcgg agagcgtcca ttccatcgag accggcgcct
    28741 ccgtgtacgg catcgacctg cagcaggcgg tcatccccct ggaggaggaa gagggcgacg
    28801 gagggcaggt caccgtccgc atctcggcgg acgtcctgtt cgacttcggc aaggcgacgc
    28861 tcaccggcgc cgcccgccgc cgcatcgccg agctggctcc ccgcctgcgc ggcgcccggg
    28921 gcgccgtcca ggtgtcgggg cactccgact ccatcggcga ctccgcctac aacctcgcgc
    28981 tctccgagca gcgggccgaa gcggtcaagg ccgagctggc gaacgccctg accgggacga
    29041 gcccgcagat cgaggccagg ggctacggcg agaccaagcc cgtcgtcccc aacgagcagg
    29101 gcggcaagga cgaccccgcg ggtcgcgcca agaaccgccg cgtcgagatc acctacgaga
    29161 agggctgacc atcgtgcggc gagcgtcgcg agcctccgcc gtcgtcctgg ccgcgggtct
    29221 gtccctggcc gcgtgcggcg gcgaggggcg accggagcga gccgggggcg ggcatgaccg
    29281 cacgggcggc gcgccggagt cgcccgcggc gaccgtgccc gcgccggagc cgtcgagctg
    29341 ccccggcggc ggccggctga tcaaggcggt cgagatcccg gccgtgcaca gcgagccggt
    29401 gcggatcccg gaggccgtga tcggcggcca gaagatcccg gccgtgacga tcccgggcgt
    29461 ggatctcccc gcccagcggg tcccggcgca gtgcgtcgag cacaggcccg ccccgggcgg
    29521 ctgcctcggg gcggtcgcca ttcccggggc ctccatcccc ggcgtgacga tccccgccgt
    29581 gcggattccc ggggtcaggg cccccggcat cgacgctccg ccggtcgagc aggcggccgt
    29641 gtcgagcacg gcggtcagcc agcaggcggt caccggcgcg gaggtctgcc agagcaagcc
    29701 gtcgaaggag ggcgagtacg tcagctcggt gtacagggcg tcgctctacc gcgccagcct
    29761 gtaccgtgcc tcggcctacc ggagcagcct ctaccgcccg cgtacctgca acgacaacaa
    29821 cgaatgcctg ccgcaggtct ccgtgcccgg cgtctccgtc ccgggcgtct ccgtcccggg
    29881 cgtcagcgtc cccggggcca ccctcaagtc gtatgtggcc gggcccgggc aggtcatcaa
    29941 gggcgatgac agcatcgcct acaacatcga ggcggacgtc ctcttcgact tcggcgcggc
    30001 cgagatcaag cccgccgcgg cggccgagct gaagaagatc gtcgagtcgc tgggccggga
    30061 ggtcccggcc ggcgcggccg tccaggtcga cggccacacc gacggcaagg gcgacacggc
    30121 gtccaaccag gccctctccc tgcgccgcgc gcaggccatc gtcgactggc tggccgccga
    30181 gggcggcatc gcccggtccc gcctcagggc caccggctac ggcgagacga aaccggctta
    30241 tcccaacacc gagccggacg gttccgacga ccccgaaggg cgcgccaaga accgccgcgt
    30301 ggtcatctcg gccgcccggt gactcaggcg ggcgcgggcg gcgggcccag gtggtcgaag
    30361 atctgcaggg gctcgccgtc cagcgtgcgg acggggaagc gcagttccag ccggcacgcg
    30421 gccagcgccc cgcgcgccgc gtcggcgtgg gcgggacgtc gccccgggtc ggccgcgcac
    30481 aggtgggcga ccaccgccca cagcaggggc ggcacaccgg ggggcggcgc gccgatccgc
    30541 tggcgcggct cggggtcccc ggcgccggtc agcatccgcc aggcgaccat gccggcggcg
    30601 tacaggtcct gccgggggcc gggccggtcc cagtcgagca cctcgggcgc gaggtatccc
    30661 ggcgtcccga cggcgaagcc ggtggtggtg aagcgctggt cggcctcccc cagcgcgatc
    30721 ccgaagtcgg ccagccgcac gtgcggcgcc ccgaccggac tcggttccag cagcaggttc
    30781 gcgggcttga cgtcccggtg gaccaccccg gcaccgtgga tgtggctcag cgcggccagc
    30841 aactggtcca ggacctcggc cgcgtacccg ggcgggagcc tgccgtagtc cccgaggagc
    30901 gtctccagcg agcccccgcg cacgaggtcc atggcgagga gcacatcgtc gtacgccgtg
    30961 cacgaggcgt agggcgtcag cacatggggg tgcgccatgc gcagcgccct ttcccggacg
    31021 acccgcagca tcgacgtggg acccggctgc cggacgagct tggccgcgca gtaccgcccc
    31081 tccgcgtggt cgtaggcgcg ccacacacgg ctggttcctc ccgccccgat ccggtcgagc
    31141 atggtgaacc gcccgccgat cacccacccc gagttcacgg caccgatcgt acggaagacc
    31201 acccgccccc ggttgccaga tttccgcaca catgtcaaca gaacgggtgt tctgcgcatc
    31261 taacaccagg agttacggac gcccctggac ggcggcctcc ctagactgac cgatcacgca
    31321 gaccacgtgc cctccccagg gcccgccccc tagacgggac cgatgagcga caaagacccg
    31381 cgccgcgacg acctcgcggg ggacgaggcc gcccgccgac cgccggcggc cccggagacg
    31441 gccggcgaca ccgccccagg ttccccggac gccggagagg cgtcgaccac cggtgggccc
    31501 gaacccggtg acggcgaaac ggccgccgcg cccagcggca cggcggccga ggagagcggc
    31561 gacgagaccg acggccccgc ggacgccgag gcggcagccg gcccgcacgc gtccggacag
    31621 gacggcgacg gcgacgccga agcgccggaa gagacggtga ccggggacaa gacggtgacc
    31681 ggcgacgagg agtcggccgc ggccggcgag gcggcggacg atgacgggcc ggacgacgcc
    31741 gcgccctccg ggaccgccgc cagagcccgg cggcgtggcg gacggcggaa ggggctgcgc
    31801 cgggtcgcgg tcgtcgcggt cgcgctgctg ctggccgcgg ggggcggcgc ggcgtggctc
    31861 tatcacgacc tcgtcggcgg gatcgagcag aagcacgtca gcgacaagct cggcacgaac
    31921 cggccgaaga agctgaacaa gtcgctcaac atcctcctca tcgggtccga cacgcgggag
    31981 ggcgagaact cggagtacgc ggtgcccggg atggccgggg cacggtcgga caccacgatc
    32041 ctgctgcatc tctcgccgaa ccgggaccag gcggtcggga tcagctttcc gcgcgactcc
    32101 atggtgaaga tgccggcatg caagaaggag aagggcggca ccgtcccggc acagttcggg
    32161 atgctgaacg cggcgttcgc ctatgcgggg ccgacgtgca cgtggaagac gctggagtcg
    32221 ctcaccggca tccacatcga ccatttcgtg caggtggact tcgccgggtt caagcggatg
    32281 gtggacgccc tgggcggcgt cgagatctgc gtcgacaagc ccgtgaggga cccgagggcc
    32341 gagctctacc tgaaggccgg gaagcagacc gtgaaggggg acgatgcgct cggctacgtg
    32401 cgcgcgcgct actcgctcgg tgacggctcg gacctggagc gcatcgaacg gcagcagaag
    32461 ttcatggcgg cggtcgtcga caaggccacc agcgggtccg tcctcaccga tcccgcgaag
    32521 acgtacaagt tcctcaaggc cgcgaccaag tcgatgacga ccgacgacga cctggatctg
    32581 gcggggatgc ggaagctggc ggacgggctg aaggggatga gcgccggcca ggtgcggttc
    32641 gtcaccgtcc ccgtggaggg gtacgcgccg gacccgaacc gcgtccagtg gaacggggag
    32701 ctcgcgaagc cgctgttcga ggcgatccgg catgacgacg agctgcccgc cgagccggtc
    32761 aagcccgccc cggcgcgacc ggtgccgccc ccgcccggca aggtgcacgt caccgtggtc
    32821 gacgcgggcg cccgggacgc gcaggtgaaa cgggtcgtga agcagctccg gcagcgcggg
    32881 ttcacggtgg cgaagaaggt cgagaagacc gccgcggc
//
