LOCUS       NZ_BMRD01000003        20747 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Actinomadura citrea strain JCM 3295 sequence03, whole genome shotgun
            sequence.
ACCESSION   NZ_BMRD01000003
VERSION     NZ_BMRD01000003.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Actinomadura citrea
  ORGANISM  Actinomadura citrea
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 632679)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: BGI assembly pipeline
            Genome Coverage                   :: 127X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014648455.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 03:26:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,339
            CDSs (total)                      :: 8,265
            Genes (coding)                    :: 8,175
            CDSs (with protein)               :: 8,175
            Genes (RNA)                       :: 74
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 90
            CDSs (without protein)            :: 90
            Pseudo Genes (ambiguous residues) :: 0 of 90
            Pseudo Genes (frameshifted)       :: 12 of 90
            Pseudo Genes (incomplete)         :: 83 of 90
            Pseudo Genes (internal stop)      :: 3 of 90
            Pseudo Genes (multiple problems)  :: 8 of 90
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:33:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 423342
            Orig. end                         :: 444089
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMRD01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20747
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="CDPS"
                     /region_number="4"
                     /rules="CDPS"
                     /tool="antismash"
     cand_cluster    1..20747
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /kind="single"
                     /product="CDPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20747
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[10000:10747](-)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10747)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
     gene            540..1034
                     /locus_tag="IEZ14_RS09880"
                     /old_locus_tag="GCM10010177_20090"
     CDS             540..1034
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018656313.1"
                     /locus_tag="IEZ14_RS09880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_20090"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_179831355.1"
                     /transl_table=11
                     /translation="MEDGTFASPGYCGVTAADEDVLQWDTRNDCEVRQILDRVADKWSL
                     LVIALLDQRSLRFTELRRRIDGISQRMLARTLRHLERDGLVSRTVHPTVPPRVDYALTP
                     MGATLHETIRSLVVWTEEHQSAIAAARTAYDARVEAERRAAEQEAAERDAVARDVLAYR
                     R"
     misc_feature    568..583
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.68"
                     /tool="antismash"
     gene            complement(1095..1943)
                     /locus_tag="IEZ14_RS09885"
                     /old_locus_tag="GCM10010177_20100"
     CDS             complement(1095..1943)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012517.5"
                     /locus_tag="IEZ14_RS09885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_20100"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_179831356.1"
                     /transl_table=11
                     /translation="MRYSINIPNFGDFADPRTVARVAEAAERAGWDGLFVWDHVVHVKS
                     DRRSFGDPWMLLTAAALATSRIRLGTLVTPVPRRRPEQLARQVATLDVLSGGRVVFAAG
                     LGGPVADEYGAFGEPTDPVLLAERLDEGLGLLERYWSGEPVTHHGRHYRVEDVALLPAT
                     AQRPRPPVWIAGFWPNRRPMRRAARWDGAVPLFGPGSHGRAPAVEDVRDLVAYVRRHRE
                     GDGPFEIVVGGASPADARDMVGPLADAGATWWDERRIIGTEENERLEPVLRRIEQGPPA
                     L"
     misc_feature    complement(1914..1928)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.94"
                     /tool="antismash"
     gene            complement(1986..3155)
                     /locus_tag="IEZ14_RS09890"
                     /old_locus_tag="GCM10010177_20110"
     CDS             complement(1986..3155)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013646.5"
                     /locus_tag="IEZ14_RS09890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_20110"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_179831357.1"
                     /transl_table=11
                     /translation="MKAVPESTGVLVVGAGPVGLSLAASLRQKGVDAVLLDRAAEGANT
                     SRAAVVHARTLEALREIDVTGELVERGIIVPRFTVRERDRVLLTVEFGDLPTDFPYTLL
                     VPQNVTEEILLGRLHAAGGLVHRPFEVTDLAQDEDGVTATLADGERIRAAYAVGTDGMH
                     STVREHAGIAFEGDAYPQSFILADVHLDWAGGSEEVMLFFSSEGVTVVAPLPGGRHRIV
                     ATVDEAPQDPTAADVQALLDARGPRRHPALIKDVVWSSRFRVHHRLAARYRAGRVFLAG
                     DSAHVHSPAGGQGMNTGIQDALGLAGKLAAVINDGAPDSVLDEYEAERRPIAEQVVSFT
                     DKMTNVATMGSPVLRGVRNTLLRTLDWIPAVHRTMAMNLSELSTDPTRR"
     gene            3267..3830
                     /locus_tag="IEZ14_RS09895"
                     /old_locus_tag="GCM10010177_20120"
     CDS             3267..3830
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037150.5"
                     /locus_tag="IEZ14_RS09895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_20120"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_179831358.1"
                     /transl_table=11
                     /translation="MAFTERSAATRTAILDAARRRFAEDGYERATIRAIAADAAIDPSM
                     VIRYFGSKAELYAAASAIDLAVPDLGDADDAAAAYVEAFLARWEAGENTAEAVLLRTAP
                     THPDAAARVQAIFDREIVPALEKVLPDDPAVRERAALLLSQTLGIAYGRYLLGIEPLAS
                     MDVREIAALAAQAARIPLHAPRTP"
     misc_feature    complement(4123..4133)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     misc_feature    4124..4134
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            4173..4475
                     /locus_tag="IEZ14_RS09900"
                     /old_locus_tag="GCM10010177_20140"
     CDS             4173..4475
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEZ14_RS09900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010177_20140"
                     /product="hypothetical protein"
                     /protein_id="WP_179831359.1"
                     /transl_table=11
                     /translation="MGELMGGFDELPRVRRGPLPSLYAALRRRAPQVATARPDGGGGLL
                     HISYRGQEARVAWDDDLEQFAWHSGGSGQIGSDVEKAAELIAWALGARTGPATSG"
     misc_feature    4302..4304
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4492..5049)
                     /locus_tag="IEZ14_RS09905"
                     /old_locus_tag="GCM10010177_20150"
     CDS             complement(4492..5049)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019631663.1"
                     /locus_tag="IEZ14_RS09905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_20150"
                     /product="DUF5063 domain-containing protein"
                     /protein_id="WP_179831360.1"
                     /transl_table=11
                     /translation="MSDTNSPQDWNALAERVACHVDNYLNGLEAVARGDGGTHTVPLLL
                     LEVSQVILAGAQLGASADVILPDNWEPEVGDDPDLDSIRQGLAERLQAMDEYVEVFDPY
                     KDTEPTSYRLSDDLVDVASDLVHGLRHYNKDRPLEALWWWQYSYFNHWGNHAGAALRAL
                     HAFVANARLSVATEVATEAAPA"
     gene            complement(5042..5641)
                     /gene="recR"
                     /locus_tag="IEZ14_RS09910"
                     /old_locus_tag="GCM10010177_20160"
     CDS             complement(5042..5641)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543008.1"
                     /locus_tag="IEZ14_RS09910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_20160"
                     /product="recombination mediator RecR"
                     /protein_id="WP_179831361.1"
                     /transl_table=11
                     /translation="MYEGVVQNLIDELGRLPGVGPKSAQRIAFHLLAADPADVERLGKA
                     LKEVKDKVRFCKTCGNVAEEEECRICRDARRDPHIICVVEESKDVVAIEKTREFRGHYH
                     VLGGAISPIEGVGPDDLRIRELMQRLADGTVTELILATDPNLEGEATATYLARLVKPMD
                     ITVTRLASGLPVGGDLEYADEVTLGRAFEGRRLLDV"
     gene            complement(5683..6051)
                     /locus_tag="IEZ14_RS09915"
                     /old_locus_tag="GCM10010177_20170"
     CDS             complement(5683..6051)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013155806.1"
                     /locus_tag="IEZ14_RS09915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_20170"
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="WP_179831362.1"
                     /transl_table=11
                     /translation="MEPGGQLNMQELLQQAQAMQEQLFNAQRELAETEVTGTAGGGLVT
                     ATVNGQGEVTGLSIDPKAIDVDDPADTAETVADLVLAAIRDAAREAQELQQEKMGPLAQ
                     GLGGGGGIPGGFPGLGGA"
     gene            complement(6239..8518)
                     /locus_tag="IEZ14_RS09920"
                     /old_locus_tag="GCM10010177_20180"
     CDS             complement(6239..8518)
                     /EC_number="2.7.7.7"
                     /GO_component="GO:0009360 - DNA polymerase III complex
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012855223.1"
                     /locus_tag="IEZ14_RS09920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_20180"
                     /product="DNA polymerase III subunit gamma and tau"
                     /protein_id="WP_179831363.1"
                     /transl_table=11
                     /translation="MSLALYRKYRPATFAELKGQEHVAEPLQQALRNGRINHAYLFSGP
                     RGCGKTSSARILARSLNCEEGPTPDPCGKCDSCVALGPSGSGHIDVIEIDAASHGGVDD
                     ARDLRERAFFAPVAARFKVYIIDEAHMVTREGFNALLKLVEEPPPHLKFVFATTEPEKV
                     IGTIRSRTHHYPFRLIPPGVLQDLVEEILKSEDVPYETSALPLAVRAGAGSARDTLSIL
                     DQLLAGSDEKGITYARAVSLLGYTDSALLDEVVAAFASRNGAAVFAAIDRVIESGQDPR
                     RFTADLLERLRDLVILSNVPEAGASGLLNFPPDELEQMRRQASSMGPGELTRAADLLHT
                     GLTEMRGATSPRLLLELICARILLPAAYEDEASMFARLDRLERQAGQGGFGGGQAGFGG
                     GQGGDPLAQAFAAPAPGQGGPGQGGAGQGAPAQGSSGQAGAAPGTSGQGGATQGTSGQP
                     TQEASEQPGAPASRDGGSQTPGTQSPPSRGADPTSSVNPTPRTAPAESGSVDNRAAAPA
                     TAPQPTAARPTAAPANARPAPSASPAPSSAPPAPAASGGGGGGADFSTIQRLWPDVVEA
                     VKQKSRATWMVIMSGVQPISLDGKVLTLGFDAEGRRLGFVNGGRDAVLREVFKERMGVD
                     WRIETVVGGASGGSPPGGRPGPSAGFGGAATPNPAPQPRPPFQPSAQSSAQPSAPRADR
                     SPEPPPPPPDEPPPPPEPSPVDESEEVDPEGDADADGTEAEMGGMALIQRELGGQIIRE
                     IDNSAL"
     ncRNA           complement(8604..8699)
                     /db_xref="RFAM:RF00169"
                     /gene="ffs"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="IEZ14_RS09925"
                     /ncRNA_class="SRP_RNA"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /product="signal recognition particle sRNA small type"
     gene            complement(8604..8699)
                     /gene="ffs"
                     /locus_tag="IEZ14_RS09925"
     gene            8758..9102
                     /locus_tag="IEZ14_RS09930"
                     /old_locus_tag="GCM10010177_20190"
     CDS             8758..9102
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019631667.1"
                     /locus_tag="IEZ14_RS09930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_20190"
                     /product="DUF952 domain-containing protein"
                     /protein_id="WP_179831364.1"
                     /transl_table=11
                     /translation="MPASPQDTLLHIAERTHWESAQSTGVAYTMSTLGRTLDEEGFIHC
                     SSDIAQVEGVLGRFYGDVPRDDLVLLVIDVSRLDAPVRYEPAGDELFPHVYGSIPVDAI
                     IDVRSLPENR"
     tRNA            9113..9200
                     /anticodon=(pos:432489..432491,aa:Ser,seq:gga)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="IEZ14_RS09935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="GCM10010177_t00250"
                     /product="tRNA-Ser"
     gene            9113..9200
                     /locus_tag="IEZ14_RS09935"
                     /old_locus_tag="GCM10010177_t00250"
     tRNA            9769..9843
                     /anticodon=(pos:433145..433147,aa:Met,seq:cat)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="IEZ14_RS09940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="GCM10010177_t00260"
                     /product="tRNA-Met"
     gene            9769..9843
                     /locus_tag="IEZ14_RS09940"
                     /old_locus_tag="GCM10010177_t00260"
     gene            complement(10001..10747)
                     /locus_tag="IEZ14_RS09945"
                     /old_locus_tag="GCM10010177_20200"
     CDS             complement(10001..10747)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017573920.1"
                     /locus_tag="IEZ14_RS09945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_20200"
                     /product="tRNA-dependent cyclodipeptide synthase"
                     /protein_id="WP_179831365.1"
                     /sec_met_domain="CDPS (E-value: 3.2e-69, bitscore: 228.1,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTSSTPAVSCTSTPGIPIDAQPYMPACRRLFEQGEHILIGVSP
                     ENSYFSRERIAALVKWAQPRFTGIDIIYVDQHIDTMYVASGYTPQKAASSATRTIRDTR
                     RRVRQAVERAGGPGPQVRVRALSECMDLPSYQATRRRIEECLSADDQLRQACEEHVRYI
                     LRSRTDDSPASAGAEAEKLQAGLAYLFAEMPVLFNTPEILGVSSSVFCYHSIMPVLRHL
                     YDSAIRHQAQGYIVVKPIEQELETRS"
     misc_feature    complement(11215..11235)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.19"
                     /tool="antismash"
     gene            complement(11359..12102)
                     /locus_tag="IEZ14_RS09950"
                     /old_locus_tag="GCM10010177_20210"
     CDS             complement(11359..12102)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1269: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF019846.5"
                     /locus_tag="IEZ14_RS09950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_20210"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_218934876.1"
                     /transl_table=11
                     /translation="MADMPRGGPCAGWWDRLYETDRLEYLDRPETADKAQRVLRGLHRL
                     QRLGGLYRIWGRWIQAEIAGLPEPRILELGAGSGGLAEHVLARHPTARWTASDISARTV
                     QTLQAGPLGRHPRAETAVIDATGIDAETGSWDLAVFAFSLHHLPPTAVRAVLREGTRVA
                     SRLLIIDGWRNPACLVTGIPVGLLLGGGQPLLHDWVISARKFYSVDALHALASDCGEAV
                     TIRCSVIMPFWTVVRARRTEQRTGP"
     gene            complement(12144..13349)
                     /locus_tag="IEZ14_RS09955"
                     /old_locus_tag="GCM10010177_20220"
     CDS             complement(12144..13349)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.5"
                     /locus_tag="IEZ14_RS09955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_20220"
                     /product="cytochrome P450"
                     /protein_id="WP_179831366.1"
                     /sec_met_domain="p450 (E-value: 2.7e-18, bitscore: 61.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDDHAPPDLPLRYPFALGPHGTPPPVLAWARENRPVCPVTLPSGD
                     RVWMITRKDDIAQVFTDRRFSRDLTYPGAPRFVGADFTVVPGVIFNLDPPDHTRIRRVL
                     NPFYTPARVERYRPMIERHADSLLEAMASGRGPADLLQVYAAPLPLRVSCELLDIPIEH
                     RVEYLHAFRTQIALNVEADQVAAATKTTLEFTEQVIAAKQAAPGGDDPVSALVRAHRNG
                     TISEQELHGTVSYLLVTGSDPLVSPVATGVITLLRHREQLGRCIAQPELWPKAVEEVLR
                     FHHNGVLGYPRVATEDVMLHGVRIVEGDGVCAPMLGATWDERHYPDPGRFDIHRTTDAT
                     ATFGAGPHFCLGAAFSRLYLTISFRALFERFPGLRLAVSEHDIPWRNDLGQTRPDQVPV
                     SW"
     misc_feature    complement(12639..12641)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(13430..13443)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.4"
                     /tool="antismash"
     gene            13486..14235
                     /locus_tag="IEZ14_RS09960"
                     /old_locus_tag="GCM10010177_20230"
     CDS             13486..14235
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.5"
                     /locus_tag="IEZ14_RS09960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_20230"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_179831367.1"
                     /transl_table=11
                     /translation="MSQFDTLAEAYEETTRRFPFREHIEAHSLLDQIGPLDGLAVLDLG
                     CGSGVYARRLRRLGAARAVGVDASAGMIEHAEKLERVEPLGVRYAAADASLGLGPDLSG
                     AFDLVVGVYLTPYAATAEELTGIFRTARQALKPTGGRFVAAVLNPGHDRAPGYYQRYGF
                     DIICEPDDEADGAPVDLSGSIDDHDFLLHGYRWSKPTHERALRAGGFSAATWVRPTLSD
                     EGRRLHPEDYWARYLARPHALILEAGA"
     gene            complement(14376..14828)
                     /locus_tag="IEZ14_RS09965"
                     /old_locus_tag="GCM10010177_20240"
     CDS             complement(14376..14828)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012895681.1"
                     /locus_tag="IEZ14_RS09965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_20240"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_229810061.1"
                     /transl_table=11
                     /translation="MRNVDDIDRQLLELLQQDATRSYAALGTAVGLSAGAVHERVRKMR
                     ERGVILRTSVDVEPAALGQGVLAFALIDSSVWMGDRAAEFAAIPEVQEAHVVAGSASVL
                     VKVRTSTTARLQDVLRRLYDIQGVSGTKATVVLETFFERPISPIGQ"
     misc_feature    14840..14855
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.3"
                     /tool="antismash"
     gene            14905..15843
                     /locus_tag="IEZ14_RS09970"
                     /old_locus_tag="GCM10010177_20250"
     CDS             14905..15843
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012895680.1"
                     /locus_tag="IEZ14_RS09970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_20250"
                     /product="SMP-30/gluconolactonase/LRE family protein"
                     /protein_id="WP_179831368.1"
                     /transl_table=11
                     /translation="MPKEAADGMYEVLDERFRTGRCCHGDQHLERLHSDARWAEGPLYL
                     PAWRQLVWSDIPNDRMLRWDEATGAVSTFRAPAGHSNGNTLDGQGRLITCEQGDRRVTR
                     TEPDGTVTVIADRYQGRRLNSPNDAVVRSDGSVWFSDPDFGITSDYEGHRAESEIGACN
                     VYRADPATGEVRLVADGFGGPNGLVFSLDERRLFVSDTRAAHIRVFDVGADGTLSDGDV
                     FAAARDGVARFDNIRLDRDGRLWAAALEGGVHCYAPDGTLIGRIRVPEPVSNITFGGPK
                     NNRLFITATTGLYSAVTSVTGLPRTPQVIES"
     gene            15902..16291
                     /locus_tag="IEZ14_RS09975"
                     /old_locus_tag="GCM10010177_20260"
     CDS             15902..16291
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012601.5"
                     /locus_tag="IEZ14_RS09975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_20260"
                     /product="cytidine deaminase"
                     /protein_id="WP_179831369.1"
                     /transl_table=11
                     /translation="MTVDQELVRAAGRVAAENSRGDEHTVAAAARARDGRIVTAMNVHH
                     FTGGPCAELAVIGAAAAQGAHQLDTVVAVGDGDRGVMSPCGRCRQILLDYFPTIRVIVD
                     MDGGLRAVPVTELLPGAYIWSDHQS"
     gene            16431..16739
                     /locus_tag="IEZ14_RS09980"
                     /old_locus_tag="GCM10010177_20270"
     CDS             16431..16739
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019631679.1"
                     /locus_tag="IEZ14_RS09980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_20270"
                     /product="type II toxin-antitoxin system VapB family
                     antitoxin"
                     /protein_id="WP_179831370.1"
                     /transl_table=11
                     /translation="MIFKAVGEGRPYPEHGLSSRDWAKIPPRQVRLDQLVSTKREMDLH
                     SLLSKDSTFYGDLFPHVVQWQGELYLEDGLHRALRAALHQRLVLHARVLDLDAVDMS"
     gene            complement(16740..17987)
                     /locus_tag="IEZ14_RS09985"
                     /old_locus_tag="GCM10010177_20280"
     CDS             complement(16740..17987)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018654171.1"
                     /locus_tag="IEZ14_RS09985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_20280"
                     /product="MFS transporter"
                     /protein_id="WP_179831371.1"
                     /transl_table=11
                     /translation="MNSSTTPGSRAAAVWSLVGLVLLTINLRAAITGISPVLGDLRDAF
                     GLSGAEAGVLTTLPVLCLGVFAAVAPVVARRFGTETAIAGSLVMITTGIVLRVVQSPVS
                     LFVGTVLAGAGIAMGNVLMPAVIKRAFPSRLGSLTGLAMMLMAASGAIAAGLAVPLEEA
                     GGWRLALAVWAVPSLVAALVWGPLALRGRRAPTPPVTAPRAGGSLLRSPTAWFVAGFMG
                     LASLMFYVLMSWLPEVMRDAGYPAATAGMMVSTMMIVGIPLGFLVPVFAARLRDQRPLV
                     LAVAATMVVGLVGLLLAPGWTWVVIIGIGTGSAFPLAFTLLSLRSPTPAAAASLSGMAQ
                     TGGYLLAGTGPLAVGVLHEVTGGWNVPLALLLVLVVPEVVVGLLAARPGFVRPAHPATP
                     LVEPKALRAPEPARSR"
     gene            complement(18153..18851)
                     /locus_tag="IEZ14_RS09990"
                     /old_locus_tag="GCM10010177_20290"
     CDS             complement(18153..18851)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012895671.1"
                     /locus_tag="IEZ14_RS09990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_20290"
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="WP_179831372.1"
                     /transl_table=11
                     /translation="MTLRTARRSSLVDQVIDQLRGEITGGGWPVGAKIPPEPVLSETLG
                     VGRNTVREAVRALTHAGLLESRQGDGTYVRATSELSGAVRRRLETAELVEILEVRRGFE
                     VEAARLAATRRTDADIAAIAVALARRDAAWAAGEHSAFVEADLEFHTAVVEATHNRVLT
                     DLYRDFSAALRASIGAAGSLLEHADVPHGPIAAAIEAGDADAATQATHACLDQILASTV
                     PLSGTAPQET"
     misc_feature    18881..18897
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.17"
                     /tool="antismash"
     gene            complement(19065..20507)
                     /locus_tag="IEZ14_RS09995"
                     /old_locus_tag="GCM10010177_20300"
     CDS             complement(19065..20507)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018654173.1"
                     /locus_tag="IEZ14_RS09995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_20300"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_179831373.1"
                     /transl_table=11
                     /translation="MPGPGNVGERVRNLRLTRRLSQAQLAGHDLSDSYISLIESGKRTP
                     TPTVLRMLAERLGCTPEYLAEGVEPEQRAHLEVRERHAHLALLRGDPATAEAGFDEVIA
                     RSDDPDLTARARLGRARALEELGRTDRAIELFEELREQAERDPGRASWLPPVIALARSY
                     HTVGDLGQAVALGERALERLERLGLHAGHEYTEAGRILLLAYVDRSDPVRAHELGRRLL
                     HPDGSKDAEPLSVHYQRASMRALDEGAVGDSLYFADQALAARTDTTPTQAHARLALAGA
                     KALLRGVEPFSVAAPPGAAPSGEYGFERPRQEGTREAAHEALTLLQDVTGLDDAESTEG
                     TIAKARALVLVGDLDEAIAALEQFLDTGMALAAPTSEHTMALQPANELGVRTQKTVLAR
                     LVLARARVAQGNTTAAQVVLRAASEQLSTLPEGRPAAHLYRELGELYELIESPDNAATA
                     YRQALEAAGLSVFNRVALSARH"
     misc_feature    complement(20556..20568)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 16.78"
                     /tool="antismash"
ORIGIN
        1 cgcggccgtc cccgcgtaga cgccgagcgc ccgggtgcga gcgggcccgg ccgggaacgc
       61 ggcggtcacc agcgcgagtc ccgccggggc catgaacgcc gacgcgaccc cggtgacgaa
      121 ccgcgcgacc agcagcatcc agccctcggt ggcgaggccg ccgagaccgg agaacaccag
      181 gaagaccgcc agccagaaca ggaagacccg ccgccggccc agcaggtccg cggcgcgccc
      241 gccgagcagc atgaacccgc cgtagccgag cacgtaggcg ctgatgacgc cgctcagcat
      301 gccggtcgac aaccccaggt ccgcccggat cgacggcagc gcgaggttga gcatcgccat
      361 gtcgatcccc tccaggaaga ccgcaccgca caggaccagc agggacgccc aggcgcggcc
      421 gtccaaacgg gacgcggatg tggacatgac ccggctcctc tcctccgagg caccggttcc
      481 cctgatggat gccggttccc tcttgttacc ggcagcatcg tccgacacca tcggtaagca
      541 tggaagacgg aactttcgcg tcccctggtt actgcggagt caccgccgcc gacgaggacg
      601 ttcttcagtg ggacacccgc aacgactgcg aggtgcggca gatcctcgac cgcgtcgcgg
      661 acaagtggtc cctgctcgtc atcgctctgc tcgaccagcg gtccctgcgc ttcaccgaac
      721 tccgccgccg gatcgacggc atcagccagc ggatgctcgc gcggacgctc cggcacctcg
      781 aacgggacgg gctcgtcagc cgcaccgtcc acccgaccgt ccccccgcgc gtcgactacg
      841 cgctcacgcc gatgggcgcg accctccacg agacgatccg gtcgctcgtg gtctggacgg
      901 aggagcacca gagcgcgatc gccgccgccc ggaccgccta cgacgcccgc gtcgaagccg
      961 aacggcgggc ggccgagcag gaggccgccg aacgcgacgc cgtggcccgc gacgtcctcg
     1021 cctaccgccg ctgatcgcac gcgaggatca ccccgccggt ttcacgggaa acctgctcgg
     1081 ccggggctgt ggcgctagag cgccggcggg ccctgctcga tgcggcgcag gacgggttcg
     1141 aggcgctcgt tctcctcggt gccgatgatc cggcgctcgt cccaccaggt cgcgccggcg
     1201 tcggccagcg ggccgaccat gtcgcgggcg tcggccgggc tggcgccgcc cacgacgatc
     1261 tcgaacggcc cgtcgccctc ccggtgccgc cggacgtagg cgaccaggtc gcggacgtcc
     1321 tcgacggcgg gcgcacggcc gtgcgagccg gggccgaaca gcgggacggc gccgtcccag
     1381 cgggcggccc gccgcatcgg ccgccggttc ggccagaacc cggcgatcca caccggcggc
     1441 cgcggccgct gcgccgtcgc gggcagcagc gccacgtcct cgacccggta gtgccgcccg
     1501 tgatgggtga ccggttcgcc ggaccagtag cgttcgagca ggccgagccc ctcgtccagc
     1561 cgctcggcga ggaggacggg gtcggtgggc tccccgaagg ccccgtactc gtcggcgacg
     1621 ggaccgccga ggcccgccgc gaagaccacc cgtccgccgc tgaggacgtc cagcgtggcg
     1681 acctggcggg ccaactgctc ggggcgccgc cgcggaaccg gcgtgaccag cgtgccgagc
     1741 ctgatccggc tggtcgccag cgccgccgcc gtcagcagca tccacggatc cccgaaggac
     1801 ctgcgatcgc tcttcacgtg gacgacgtgg tcccacacga acagcccgtc ccacccggcc
     1861 cgctccgccg cctccgcgac ccgcgccacg gtccgcggat cggcgaagtc cccgaagttc
     1921 ggaatattga tcgagtaccg catccccgca tgctgcgccg tcccccgcgc ccgcggcaaa
     1981 tcgctttagc ggcgggtggg gtcggtggac agctcggaga ggttcatcgc catcgtgcgg
     2041 tggacggcgg ggatccagtc gagagtgcgc agcagcgtgt tgcgcacccc gcgcagcacc
     2101 gggctgccca tggtcgcgac gttggtcatc ttgtcggtga acgagacgac ctgctcggct
     2161 atgggacggc gttcggcctc gtactcgtcc agcacggagt cgggggcgcc gtcgttgatc
     2221 acggcggcga gctttcccgc caggccgagg gcgtcctgga tgccggtgtt catgccctgc
     2281 ccgcccgccg ggctgtggac gtgcgcggag tcaccggcca ggaagacgcg gcccgcccgg
     2341 tagcgcgccg ccagcctgtg gtggacgcgg aagcgggagc tccacacgac gtccttgatc
     2401 agcgcggggt ggcgcctggg accgcgcgcg tccagaagcg cctggacgtc ggcggcggtc
     2461 gggtcctggg gcgcctcgtc gacggtcgcg acgatgcggt gccgcccgcc gggcagcggc
     2521 gcgacgaccg tgaccccctc cgaggagaag aacagcatga cctcctcgct gccgccggcc
     2581 cagtccaggt gcacgtcggc gaggatgaac gactgcgggt aggcgtcgcc ctcgaacgcg
     2641 atcccggcat gctcgcggac cgtgctgtgc atcccgtccg tcccgaccgc gtaggccgcg
     2701 cggatccgct cgccatcggc cagggtcgcc gtcaccccgt cctcgtcctg cgccaggtcc
     2761 gtcacctcga acggccggtg cacgaggccg cccgccgcgt gcagccgtcc gagcaggatc
     2821 tcctcggtga cgttctgcgg gacgagcagc gtgtagggga agtcggtcgg caggtcgccg
     2881 aactcgacgg tgagcagcac gcggtcccgc tcacggacgg tgaagcgcgg cacgatgatc
     2941 ccgcgctcga ccagctcgcc ggtcacgtcg atctcgcgca gggcctccag cgtgcgggca
     3001 tggaccacgg ccgcccggga ggtgttcgca ccctccgccg cccggtccag caggacggcg
     3061 tccaccccct tctgccgcag cgaggcggcg agggacagcc cgacgggccc cgcgccgacc
     3121 acgagcacgc cggtggactc cggaacagcc ttcatgatca ctcctgtcgc caatgaccgt
     3181 ttgccaacac ctgttggcca acttgtgatg gactctagac cgttgccacc gtgtttgcca
     3241 acgcttgatg gcataggttg gcgggcatgg ctttcaccga gcgttccgcg gcgacccgga
     3301 cggcgatcct ggacgcggcc cggcgccggt tcgccgagga cggctacgag cgcgcgacga
     3361 tccgggcgat cgcggcggac gccgccatcg acccgtccat ggtcatccgg tacttcggca
     3421 gcaaggccga gctctacgcc gccgcctcgg ccatcgacct cgccgtcccc gacctcggcg
     3481 acgccgacga cgcggcggcc gcctacgtcg aggccttcct ggcccgctgg gaggcaggcg
     3541 agaacaccgc cgaggccgtc ctgctgcgga cggcccccac ccatcccgac gccgcggccc
     3601 gcgtccaggc catcttcgac agggagatcg tccccgccct ggagaaggtc ctgccggacg
     3661 accccgccgt ccgcgagcgc gccgccctgc tgctgagcca gaccctcggc atcgcctacg
     3721 gccgctacct gctgggcatc gagcccctgg cctccatgga cgtacgcgag atcgccgcct
     3781 tggccgccca agccgccagg atccccctcc acgccccccg aaccccctga acccgctttc
     3841 gcggggcacc cggcgcgtcg gcgctcccgc gccggacgcg caccgcctgc tcggtgggcc
     3901 gagagcggag gccagggcga aacccgccaa tgccggtggt ggtgctggga ttcgctgcgg
     3961 cgctggtgac acgagggttg ctgcgtcgta agtggtatga cgcctcttcg gtcaccgtac
     4021 agatcatttc cgcggacctc ccggacgcgg ggtcaagcgt ctaggtaaag gcaggcgtcg
     4081 acggggtgcg gtggtcatct cgtccaccgg gttcgccgtg tcgtgccatg gcacggctcg
     4141 gcccggggcg ggcgcgggcg gtgagggagt tgatgggaga gctgatgggc gggttcgacg
     4201 agttgccgag ggttcgccgg ggaccgctgc cgtccctcta cgcggcgctg cggcggaggg
     4261 ctccgcaggt ggcgacggcg cggccggacg gcggcggggg cttactgcac atctcctacc
     4321 ggggtcagga ggcccgggtc gcctgggacg acgacctcga acagttcgcg tggcactccg
     4381 ggggaagcgg ccagatcggc tcggacgtcg agaaggcggc cgagctgatc gcgtgggcac
     4441 tcggcgcacg caccggcccc gccacgtccg gctaggcggg gcacggccgg gtcaggcggg
     4501 ggcggcttct gtggccactt ccgtggcgac gctcaggcgg gcgttggcga cgaaggcgtg
     4561 cagggcccgc agagcggcgc cggcgtggtt gccccagtgg ttgaagtacg agtactgcca
     4621 ccaccagagg gcttccaggg ggcggtcctt gttgtagtgg cggagcccgt ggacgaggtc
     4681 gctggcgacg tccacaaggt cgtccgacag gcggtaggag gtcggctcgg tgtccttgta
     4741 gggatcgaag acctcgacgt actcgtccat ggcctggagg cgctcggcca ggccctgccg
     4801 gatcgagtcg aggtcggggt cgtcgcccac ctcgggctcc cagttgtccg gaaggatcac
     4861 gtcggcgctg gcgccgagct gcgcccccgc caggatgacc tgcgacacct ccagcaggag
     4921 gagcgggacg gtgtgcgtcc cgccgtcgcc gcgggcgacc gcctccaggc cgttcaggta
     4981 gttgtcgacg tggcacgcca cgcgttcggc gagggcgttc cagtcctgcg ggctgttggt
     5041 gtcagacatc gagcagcctc cgtccttcga atgcgcggcc cagtgtgacc tcgtcggcgt
     5101 actcgaggtc gccacccacc ggaaggccgc tggccagtcg ggtgacggtg atgtccatgg
     5161 gcttgaccag ccgggcgagg tacgtcgcgg tcgcctcgcc ctccaggttg gggtcggtgg
     5221 cgaggatcag ctcggtcact gtcccgtccg cgaggcgctg catcagctcg cggatgcgca
     5281 ggtcgtccgg cccgacgccc tcgatcgggc tgatcgcgcc gccgagcacg tggtagtggc
     5341 cgcggaactc gcgggtcttc tcgatcgcga cgacgtcctt ggactcctcc accacgcaga
     5401 tgatgtgggg gtcgcggcgc gcgtcgcggc agatccggca ttcctcttct tctgcgacat
     5461 tcccgcaggt tttgcagaag cggaccttgt ccttgacctc tttgagcgcc ttgccgaggc
     5521 gctcgacgtc ggccggatcg gcggcgagga ggtggaaggc gatccgctgc gcgctcttgg
     5581 ggccgacgcc gggcagcctg cccagctcgt cgatgaggtt ctgaaccacc ccttcgtaca
     5641 acggacccct cctttactgt cgtcttctgc ccgcgtccgg gttcaggcgc cgccgaggcc
     5701 ggggaaaccg ccggggatgc ccccgccgcc gccgagcccc tgggcgagcg ggcccatctt
     5761 ctcctgctgg agctcctgcg cctcgcgggc ggcgtcgcgg atcgcggcca gcaccaggtc
     5821 ggcgaccgtc tccgccgtgt cggccgggtc gtcgacgtcg atcgccttcg ggtcgatcga
     5881 cagccccgtg acctcgccct gcccgttgac cgtcgcggtc acgagcccgc cgccggcggt
     5941 ccccgtcacc tcggtctccg cgagctcgcg ctgggcgttg aagagctgct cctgcatggc
     6001 ctgcgcctgc tggaggagtt cctgcatgtt cagctgacca ccgggttcca cggtgcactc
     6061 cctcttccgg cccccgaggg ccttctctct ggcgctccgc cagccaccgg acgtccgtcc
     6121 cacgagacta cgggttccca ggccgtttcg gtacgcgagg cccccagcgc gccatttcgg
     6181 aagcacatcc gggattcggc gccctaccgg acccccgccg aggccccctg ccgccgggtc
     6241 agagagccga gttgtcgatc tcgcggatga tctgaccgcc gagttcgcgc tggatgaggg
     6301 ccatcccgcc catctcggcc tcggtgccgt cggcgtcggc gtcgccctcc gggtcgacct
     6361 cctcgctctc gtccacggga gagggttcgg gcggcggcgg gggctcgtcc ggcggcggcg
     6421 gaggcggctc cggggaccgg tcggccctcg gcgcggacgg ctgtgcggac gactgcgcgg
     6481 acggctggaa gggcggccgc ggctgcggtg ccgggttcgg tgtggccgcc ccaccgaacc
     6541 ccgcgctagg gcccggcctt ccccctgggg gagacccgcc ggacgctccg ccgacgacgg
     6601 tctctatccg ccagtcgacg cccatccgct ccttgaagac ctcgcgcagg acggcgtcgc
     6661 ggccaccgtt gacgaagccg aggcggcgtc cctccgcgtc gaagccgagg gtgaggacct
     6721 tgccgtcgag ggagatcggc tgcaccccgg acatgatgac catccaggtg gcgcggctct
     6781 tctgcttgac ggcctcgacg acgtccggcc agagccgctg gatggtggag aagtcggccc
     6841 ctccgcctcc tccgccggac gcggcgggtg ccggcggcgc gctggagggc gcgggtgacg
     6901 cgctgggggc ggggcgcgcg ttggccggcg cggccgtggg gcgggcggcc gtgggctggg
     6961 gggcggtggc cggggcggca gcgcggttat ccacagaacc ggactccgcg ggcgccgtac
     7021 ggggggtggg gttgacactg gaagtggggt cggccccccg ggagggaggg gactgggttc
     7081 cgggcgtttg agaacccccg tcacgggacg ccggcgcccc tggctgctcc gacgcctcct
     7141 gcgtcggctg cccggacgtc ccttgcgtcg caccgccctg cccggacgtt ccgggcgccg
     7201 cgccggcctg ccccgaagat ccttgagcgg gagctccctg acctgcgccg ccctggcccg
     7261 gaccaccctg gccaggggcc ggagccgcga aggcctgcgc cagagggtca ccgccctggc
     7321 cgcccccgaa tccggcctgg ccaccgccga aaccgccctg gccggcctgg cgttccagac
     7381 ggtcgaggcg ggcgaacatg gacgcttcgt cctcgtacgc cgccggcagc aggatccggg
     7441 cgcagatcag ttccagcagc agccgcgggg acgtggcgcc ccgcatctcg gtgagcccgg
     7501 tgtgcagcag gtcggcggcg cgcgtcagct ctccgggccc catcgaggac gcctggcgcc
     7561 gcatctgctc cagctcgtcg ggcgggaagt tcagcagccc cgaggccccg gcctccggga
     7621 cgttcgacag gatcaccagg tcgcggaggc gttccagcag gtcggcggtg aagcggcgcg
     7681 ggtcctggcc gctctcgatc acgcggtcga tggcggcgaa caccgcggcg ccgttccggg
     7741 aggcgaaggc ggcgacgacc tcgtccagca gcgcggagtc ggtgtagccg agcagcgaca
     7801 cggcccgcgc gtacgtgatg cccttctcgt ccgaccccgc gaggagctgg tccaggatcg
     7861 agagcgtgtc gcgcgcggaa ccggccccgg cccggacggc caacggcagc gcggacgtct
     7921 cgtacgggac gtcctcgctc ttcaggatct cctcgacgag gtcctggagg acgcccggcg
     7981 ggatcagccg gaacgggtag tggtgggtcc gggaccggat cgtcccgatg accttctccg
     8041 gctcggtcgt cgcgaacacg aacttcaggt gcggcggcgg ctcctcgacg agcttcagca
     8101 gcgcgttgaa gccctcgcgg gtgaccatgt gcgcctcgtc gatgatgtac accttgaagc
     8161 gcgccgcgac cggggcgaag aaggcccgct cccgcaggtc gcgggcatcg tccacaccac
     8221 cgtgggacgc ggcgtcgatc tcgatcacgt cgatgtgccc agacccggac ggtccgagcg
     8281 cgacgcacga gtcgcacttg ccgcacgggt cgggggtcgg cccctcctcg cagttcagcg
     8341 agcgggcgag gatccgggcg ctggaggtct tgccgcagcc gcgcggaccg ctgaacaggt
     8401 acgcgtggtt gatccggccg ttgcgcagcg cctgctggag gggctcggcg acgtgttcct
     8461 gccccttcaa ctcggcgaac gtcgctggcc ggtacttgcg gtacagagcc agactcatcg
     8521 gggtccgccc tccctcgaga agcagagcgt cagaagcgcc gtgtcgccgt ggaccggtcg
     8581 tcgcggaccg gtcgccgtca aactaaaggg accccccgca cacccgccag agcctgctta
     8641 tccttgctgc cttccggccc tggggaggtt cacagggtga cgccgtgcga ggggtctgac
     8701 caaagtctat ggcatccccg gcccaggagc gccacgcatt cggcgtagtc tccgcccatg
     8761 cccgcctctc cccaggacac gctcctgcac atcgccgaac gaacccactg ggaatccgcc
     8821 cagagcaccg gcgtggcgta caccatgtcc accctgggcc ggaccctgga cgaggagggc
     8881 ttcatccact gctcgtccga tatcgcccag gtggaaggcg tcctgggccg cttctacggc
     8941 gacgtccctc gcgacgacct ggtcctgctg gtcatcgacg tctcccgcct cgacgcgccc
     9001 gtccgctacg agcctgccgg cgacgagctg ttcccccacg tctacggatc gatcccggtc
     9061 gacgcgatta ttgatgtcag gtcactgccc gagaaccggt aggattcccg gtggaggatt
     9121 cgcctagtgg cctagggcgc acgcttggaa agcgtgttgg gttcacgccc tcacgagttc
     9181 gaatctcgta tcctccgcca cgcttcacca ggcacaacac gctgagggcg gcacccagag
     9241 ggtgtcgccc tcagcgcatc tagtcacagc gtcagtctca atagatcgtc accgctggtg
     9301 cctttgggca cggcggcaca cgcctgcccc gtcagagcgc cttgcgccta cgccgcaggt
     9361 gcggcgacga cgaagcggct cgtgacgcgc gtgggcttcc cgtcgatcat gccgtccggc
     9421 ggtgtgcgca gggctccgtt cgaggacccc gtgccagcaa cccgacgtcc ccgctcgtct
     9481 cggaacagac agcgtcaaac ccgagcggcc ggctgtccgc gccaggcgga tgcgagtcgg
     9541 actcctcctg gtgcggcact gcttcgcgta aaggcgcgga gcgtggtgtc ggccggataa
     9601 caagactccg ccttctcgac atcccgccga aattaggcat tccgtactat ccgagctgga
     9661 taaacaacgc tggacgcgaa aggatatttg gaggccgatt ggccctggta gatcagttca
     9721 ggggacgata cgatgtcatc ggccgaacag tgagaagtgt tcggcaaagg cggagtggag
     9781 cagctcggta gctcgctgga ctcattatcc agaggtcgcg tggttcaaat cccgtctccg
     9841 ccacttccct tcgggcgtgt cgttgaccgt tgtcccaggg ttcggcagtc ggcgcggtag
     9901 ccgccgaacc ctgggcccag cggggaggca cgccggcttg agatcgtgcc cttttcctgc
     9961 ttgccgggtc attcgcctcc gttgtgggct cgccgccgag tcaggagcgt gtctccagct
    10021 cctgttcgat cggcttcacc acgatgtaac cttgggcttg gtggcggatg gcggagtcgt
    10081 aaaggtgccg caggactggc atgatgctgt ggtagcagaa caccgaagat gacactccga
    10141 ggatttccgg ggtgttgaac agaacgggca tctccgcgaa caggtaggcg agtcctgcct
    10201 gaagtttctc agcctccgct ccagcggagg ccggcgagtc gtcggtccgc gaccgcagga
    10261 tgtaccgcac gtgctcttcg cacgcctgcc ggagttggtc gtccgcgctg aggcactcct
    10321 cgatccgccg ccgggtcgcc tgatagctgg gcaggtccat gcactcggag agcgcgcgca
    10381 cgcggacctg gggccccgga ccgcccgctc tctcgaccgc ctgccgaacg cggcgccggg
    10441 tgtcccggat ggtccgggtg gcactcgagg cggccttctg cggggtataa ccggaggcga
    10501 cgtacatggt gtcgatgtgc tggtcgacat agatgatgtc gattccggtg aagcgtggct
    10561 gagcccattt caccagggcc gcgatgcgct cgcggctgaa gtagctgttc tctgggctca
    10621 caccgatgag gatatgctcg ccctgctcga acagtcgccg gcaggcgggc atgtacggtt
    10681 gcgcgtcgat cggtatccct ggggtggacg tacaggagac cgcgggggtg gacgaggtct
    10741 tgttcatctg ggggaccgcc agttcgttgc ggaggttttc gggcgtgttt cgaggctctc
    10801 ctcggatggg caggggtgtg gtggcggctt cccgtggaat tgtcccgaat cggccgtggt
    10861 ggggcctgat cgcggaccat cccgaggcac tcgcgcaccc gcggatgccc atcgcgatgt
    10921 ctcgttcacg gtgagtagtg taaggcgtgt ttgtggaaat cggtggcggc gagcggactt
    10981 attaatgtgg cggatccgtc ttccctgcat tcgttctgtg tggcgaacgc gcccggtatc
    11041 tgggaacggc ggcctccaac gagagatcga tatcgatcag acgatctcaa ggctggtgga
    11101 tttgccggga tgttgaacga ccgggatccg cggcacatcg gcgtccccca cgatttcgac
    11161 atcggccgcg ccgattccgg ccatcgtcgt tcggcaccgg cacgcatttc tgcattggcg
    11221 tctacctgac gcgtaccgac ctgcgcaccg ctctgccggc tctgagcaca cggctgcacg
    11281 ggcagcgggc gacggtgccg cccgaggaga ttccctggtc cagcgaaatg tccctgcagg
    11341 ggccgcaggt acagccggtc agggcccggt gcgttgttcg gtccgccggg cgcggaccac
    11401 cgtccagaag ggcatgatga cactgcagcg gatggtgacg gcctctccac agtcagaggc
    11461 cagggcgtgc agcgcatcga cgctgtagaa cttgcgggcg ctgatcaccc agtcgtgcag
    11521 gagtggctgc cctcctccca ggagcaaccc cacgggaatg ccggtgacca ggcacgccgg
    11581 attgcgccag ccgtcgatga tcagcaggcg ggatgccacc cgcgtaccct cccgcaagac
    11641 cgcccggacc gcggtgggag gcagatggtg aagggagaag gcgaacactg ccagatccca
    11701 tgatccggtc tcggcgtcga tgccggtggc gtcgatcacc gccgtctccg cgcgagggtg
    11761 gcgccccagc ggtccggcct gcagggtctg cacggtccgc gccgagatgt cgctggcggt
    11821 ccagcgggcg gtcgggtgcc gggccagcac gtgctcggcc agcccgcccg agcccgcacc
    11881 gagttccagg attcgtggtt ccggcaaccc ggcgatctct gcctggatcc accggcccca
    11941 gattcggtac agcccaccca gacgctgaag gcggtgcagg ccccggagca ctcgctgtgc
    12001 cttgtcggcc gtctcgggcc ggtcgaggta ttccagccgg tccgtctcgt acaggcggtc
    12061 ccaccatccg gcgcagggtc ctccacgcgg catgtccgcc atgggcctcg tcggtcccat
    12121 cgatccgccc ttctgcgagt gcctcaccag gagaccggga cctggtcggg acgggtctgc
    12181 cctaggtcgt tccgccaggg aatgtcgtgt tcggacactg ccaaccggag gcctgggaag
    12241 cgctcgaaca gtgcccggaa ggaaatggtg aggtagaggc gggagaaggc cgcacccagg
    12301 cagaagtggg ggcccgcgcc gaaggtggcg gtggcgtcgg tggtgcgatg gatgtcgaac
    12361 ctgcccgggt cgggatagtg gcgttcgtcc caggtggctc cgagcatcgg cgcgcagacg
    12421 ccgtcccctt cgacgatgcg cactccgtgg agcatgacgt cttccgtggc cacgcgcgga
    12481 tagcccaaga ccccgttgtg gtggaagcgc agcacctcct cgacggcctt gggccacagc
    12541 tccggctggg caatgcaccg accgagttgc tcgcggtgcc gcaggagggt gatgactccg
    12601 gtcgcgacgg gcgagaccag cgggtcggag ccggtcacta acaggtagct gacagtgccg
    12661 tggagctcct gctcgctgat ggtcccgttg cgatgcgccc ggacgagtgc gctgaccggg
    12721 tcgtcgccgc cgggtgctgc ctgcttggcg gcgatgacct gttcggtgaa ctccagagtg
    12781 gtcttggtgg cggcggcgac ctggtcggcc tcgacgttga gggcgatctg ggtccggaag
    12841 gcgtgcagat actccacacg gtgctcgatc gggatgtcca gcagttcgca gctgacccgc
    12901 agaggcagcg gcgcggcgta gacctggagg aggtcggcgg ggccgcggcc tgaagccatg
    12961 gcctccagca gcgagtctgc atgccgttcg atcatcggcc gataccgctc gacgcgggcg
    13021 ggcgtgtaga aggggttgag gacgcggcgg atccgggtgt ggtcgggcgg gtcgaggttg
    13081 aagatcacgc cgggaacgac ggtgaagtcg gcgccgacga agcgcggagc gccgggatag
    13141 gtcaggtctc gcgagaagcg gcggtccgtg aagacctggg cgatgtcgtc cttgcgcgtg
    13201 atcatccaca cccgatcgcc gctcggcagg gtaacggggc agacgggtcg gttctcgcgg
    13261 gcccaggcca ggacgggcgg cggggtcccg tgcgggccga gggcgaaggg atagcgaagc
    13321 gggaggtcgg ggggagcgtg gtcgtccatc agcgtccttt gccgtcgggg tgatccgatg
    13381 gtgtcggggg cgatcggggg gcgcggcggg gtatcccatc ccaaggttat cacttagagt
    13441 tgccaagggg atactatacg tgagcgaagg gggagatagg tgatcatgag ccagttcgac
    13501 acgctcgccg aggcgtacga ggagaccacg cggaggttcc cgttccgcga gcacatcgag
    13561 gctcacagcc tcctcgacca gatcgggccg ctcgacggcc tggcggttct ggacctcggc
    13621 tgcggcagtg gcgtctacgc ccgcaggctc cggcgcctcg gcgccgcccg cgcggtcggc
    13681 gtcgacgcct ccgccggcat gatcgaacac gccgagaagc tggagcgggt cgagccgctc
    13741 ggtgtccgct acgccgccgc cgacgcctct ctcggcctgg gcccggacct ctctggcgcc
    13801 ttcgacctgg tcgtcggcgt ctacctcacc ccctacgccg cgacggcgga ggagctgacc
    13861 ggcatcttca ggacggccag gcaggcgctc aaacccaccg gcggccggtt cgtcgcggcg
    13921 gtgctcaatc cgggccacga ccgagcaccc ggctactacc agcggtacgg gttcgacatc
    13981 atctgcgagc ccgacgacga ggcggacggc gcgccggtgg acctgtcggg gtcgatcgac
    14041 gatcacgact tcctgctgca cggctaccgc tggtcaaagc caacgcatga gcgggcgctc
    14101 cgggccggcg ggttcagtgc cgcgacctgg gtccgtccga ccctgtcgga tgagggacgt
    14161 cggctccatc cggaagacta ctgggcccgc tacctcgccc gcccccacgc gctgatcctt
    14221 gaagccggcg cctgactacg ggtaacaaca gcctggcccg cagacgtgga aagcgtgttg
    14281 cgtgcaggcg ctcgcgagtt cggatctcgc atcctccgcc acaccgaggc cggtgcccga
    14341 cgcgggcacc ggccttgcat gtccggcgga cggcgtcact ggccgatcgg ggagatgggg
    14401 cgttcgaaga acgtttccag gaccaccgtc gccttcgtcc cgctgacgcc ctggatgtcg
    14461 tagagccgcc gcaggacgtc ctggagccgc gcggtcgtcg acgtccgcac cttgacgagc
    14521 acggacgcgc tgcccgcgac gacatgggcc tcctgcacct ccggtatggc ggcgaactcg
    14581 gctgcgcggt cgcccatcca gaccgaggag tcgatcaggg cgaaggccag cacgccctgc
    14641 ccgagcgcgg ccggctccac gtccacgctg gtccgcagga tgacgccccg ctcgcgcatc
    14701 ttccggaccc gctcgtggac ggccccggcc gacaggccga ccgccgtgcc gagcgccgca
    14761 taggaccggg tggcgtcctg ctggaggagt tccagcagct gacgatcgat gtcatccacg
    14821 ttcctcacag gatgactgta tcgcgtatga tcatcccgaa gtagctctga actagattca
    14881 gtcatgtagg cgcgagagga aaccatgccc aaggaagcag ccgacggaat gtacgaggtt
    14941 ctggacgaac gcttccgcac cggacgttgc tgccatggcg accagcacct cgaacgcctg
    15001 cactcggacg cacgctgggc cgagggcccc ctctacctgc ccgcctggcg gcagctggtc
    15061 tggagcgaca tccccaacga ccgcatgctt cgctgggacg aggcgaccgg cgccgtctcg
    15121 acgttccgcg cgccggccgg gcacagcaac ggcaacaccc tcgacgggca gggccggctg
    15181 atcacttgcg agcagggcga tcggcgggtg accaggaccg agccggacgg caccgtcacc
    15241 gtcatcgccg accgctacca gggcaggcgc ctcaacagcc cgaacgacgc ggtcgtgcgc
    15301 tccgacgggt cggtctggtt ctccgacccc gacttcggca tcaccagcga ctacgagggg
    15361 caccgcgccg agagcgagat cggcgcctgc aacgtctacc gggccgatcc ggcgaccggc
    15421 gaggtccgcc tcgtcgcgga cgggttcggc gggccgaacg gcctcgtgtt ctccctggac
    15481 gagcgccgcc tcttcgtgtc cgacacccgc gcggcgcaca tccgcgtctt cgacgtcggc
    15541 gccgacggca cgctctcgga cggcgacgtc ttcgccgcgg cccgcgacgg cgtcgcccgg
    15601 ttcgacaaca tccggttgga ccgggacgga cggctgtggg cggcggccct ggagggcggc
    15661 gtgcactgct acgccccgga cggcaccctc atcgggcgca tccgcgtccc cgagcccgtc
    15721 tccaacatca ccttcggcgg ccccaagaac aaccgcctgt tcatcaccgc gacgaccggc
    15781 ctgtactcgg cggtgacctc ggtgaccggc ctcccgagaa ccccgcaagt gatcgagagc
    15841 tgaccccgcc gtcccgctct gtttccggca atactggtct tctggacatc tggaggcgga
    15901 catgacggtc gaccaggagc ttgttcgggc ggccgggcgc gttgccgccg agaacagccg
    15961 gggggacgag cacacggtgg cggccgccgc tcgcgcgcgg gacgggcgga tcgtcaccgc
    16021 gatgaacgtc caccacttca ccggcggccc gtgcgcggag ctggccgtga tcggtgcggc
    16081 cgccgcccag ggcgcccacc aactggacac ggtcgtcgcg gtgggggacg gcgaccgcgg
    16141 agtgatgtcg ccctgcggtc ggtgtcggca gatcctcctc gactacttcc ccaccatccg
    16201 cgtcatcgtg gacatggacg gcggtctgcg cgccgtgccc gtgaccgaac tgcttcccgg
    16261 cgcctacatc tggtctgacc accagtcgtg agcggccgca cccatctgtt cggtactaag
    16321 tcacggacgt attgagctgg gcggtaactg gtttaccgaa tccggaaagc agagtgacgc
    16381 atgttgttgc gcgccttctc cgcgcactgg cgagcccgta gactcgaagg gtgatcttta
    16441 aggcggtggg tgaaggaagg ccctatccag agcacggtct ctcgtcccgg gactgggcca
    16501 agatcccccc tcgccaggtc cgcctcgacc agctcgtcag caccaagcgg gagatggatc
    16561 tccactcgct gctgtcgaag gactccacgt tctacggcga cctgttcccc cacgtggtcc
    16621 agtggcaggg cgagctctac ctggaggacg gcctgcaccg ggcgctccgg gcggcgctgc
    16681 accagcggct cgtcctgcac gcgcgcgtcc tcgacctgga cgccgtcgac atgtcctgat
    16741 cagcgggaac gggcgggctc cggtgctcgg agggccttgg gctcgaccag cggcgtcgcc
    16801 gggtgggccg ggcgcacgaa cccggggcgg gcggccagca ggccgaccac gacctccggg
    16861 accaccagga cgagaagcag ggccaatggc acgttccagc cacccgtgac ctcgtgcagg
    16921 acgccgaccg cgagcgggcc ggttccggcg aggaggtagc cgcccgtctg cgccatcccc
    16981 gacaggctcg cggcggcggc cggggtcggt gagcggaggc tgagcagcgt gaaggccagc
    17041 gggaacgcgc tgccggtgcc gatgccgatg atcacgaccc acgtccaccc gggggcgagc
    17101 agcagcccga ccaggccgac gaccatcgtg gccgcgacgg cgaggacgag ggggcgctgg
    17161 tcgcgcaggc gggccgcgaa caccggcacc aggaagccca gcgggatccc gacgatcatc
    17221 atggtggaga ccatcatccc ggcggtcgcg gccggatagc cggcgtcgcg catgacctcc
    17281 ggaagccacg acatcagcac gtagaacatc agcgacgcca ggcccatgaa cccggcgacg
    17341 aaccaggccg tcggggagcg cagcagtgat cctccggcgc gcggggcggt gaccggcggc
    17401 gtcggggcgc ggcggccgcg cagggcgagc gggccccata cgagcgctgc gaccagcgac
    17461 ggaacggccc agacggcgag cgcgagccgc cagccccccg cctcctccag cggcaccgcg
    17521 agcccggcgg cgatcgcacc gctggccgcc atcagcatca tcgcgagccc ggtcagcgag
    17581 ccgaggcggg acgggaacgc gcgcttgatc acggccggca tgagcacgtt gcccatcgcg
    17641 atccccgcgc cggccaggac cgttccgacg aacagcgaga ccggggactg caccacccgc
    17701 agcacgatcc ccgtcgtgat catgacgagg gagccggcga tcgcggtctc ggtgccgaac
    17761 cgccgcgcga cgaccggcgc gacggccgcg aacacgccca ggcacagcac cgggagcgtg
    17821 gtgaggacgc ccgcctccgc gcccgacagc ccgaacgcgt cgcgcaggtc gccgagcacg
    17881 ggcgagatcc ccgtgatcgc ggcacgcagg ttgatcgtca gcagcaccag gccgacgagc
    17941 gaccacacgg ccgcggcccg ggaacctgga gtcgtagagc tgttcatgtc accttcgttg
    18001 ttcggtcgct tcgagcacag gttctgctgc gccgagctgg ttctgctgcg ttccggtgcc
    18061 cgtgccctgc cggtcgccgg gcaccctgac ggccgcccca tgaggtgggc gggtcacgcc
    18121 cccggtcatg gtgcgggctt gcgcctaccg cgctaggtct cctgcggagc cgttccggac
    18181 agggggacgg tcgaggcgag gatctggtcg agacacgcgt gggtcgcctg ggtggcggcg
    18241 tcggcgtcgc ccgcctcgat ggccgcggcg atggggccgt gcgggacgtc ggcgtgttcg
    18301 agcaggctcc cggccgcgcc gatgctggcc cggagcgccg cgctgaagtc gcggtacagg
    18361 tccgtcagga cgcggttgtg ggtggcctcg acgacggcgg tgtggaattc gaggtccgcc
    18421 tcgacgaacg ccgagtgctc gcccgccgcc catgccgcgt cccggcgcgc gagcgcgacc
    18481 gcgatggcgg cgatgtcggc gtccgtgcgc cgggtggcgg cgagcctggc cgcctccacc
    18541 tcgaaccccc gccggacctc aaggatctcg acgagttccg cggtctccag ccgccgccgg
    18601 acggccccgg aaagctcgct cgtcgcgcgc acgtacgtcc cgtcgccctg gcggctctcc
    18661 aggagccccg cgtgggtcag cgcccgcacc gcctcccgga cggtgttgcg cccgaccccg
    18721 agcgtctccg acagcaccgg ctccggcggg atcttggcgc ccaccggcca cccgcccccg
    18781 gtgatctccc ccctgagctg gtcgatcacc tggtcgacca gcgacgaccg ccgtgccgtc
    18841 cgcagagtca cccgaacctc cagtcaacca gtcatcccat gtttaatcat acgacatcca
    18901 tgaccctcgg tttattccgg ccccaccgct cagggtcatg gagacgttcg ggcagcgccg
    18961 atcccagcgg tcatggctcc gcgctcggtg atcgaatggc acacccgacg gcgaggcgag
    19021 gcggcacgcg ttgtcgcggc cgcctcgccc tgcccgcgaa cgatctagtg ccgggcgctc
    19081 agggcgacgc ggttgaagac cgacagaccg gccgcctcca gggcctgacg gtaggcggtg
    19141 gcggcgttgt cgggagattc gatcagttcg tagagttcgc cgagttccct gtagaggtgc
    19201 gccgcgggac gtccctcggg aagggtcgac agttgttccg aggcggcgcg aagcacgacc
    19261 tgggcggccg tggtgttgcc ctgggccacc cgtgcgcgag ccaggaccaa gcgggccaga
    19321 acggtcttct gggtgcggac gccaagctcg ttggcgggct ggagcgccat ggtgtgttcg
    19381 ctcgtggggg cggcgagcgc catgccggtg tcgaggaact gttcgagcgc ggcgatcgcc
    19441 tcgtccaggt cgccgacgag gacgagcgcg cgggccttgg cgatggtgcc ttcggtggat
    19501 tcggcgtcgt cgagaccggt cacgtcctgg aggagggtga gcgcctcgtg ggccgcttcg
    19561 cgggtccctt cctggcgcgg gcgctcgaac ccgtactcac cggacggtgc ggcgccgggc
    19621 ggcgcggcta cggagaacgg ctcgacaccc ctgagcagcg ccttggctcc tgcgagggcg
    19681 aggcgtgcgt gggcctgcgt gggggtcgtg tccgtgcggg cggcaagggc ctggtcggcg
    19741 aagtacaggg agtcgccgac cgccccctcg tccagcgccc gcatgctggc ccgctggtag
    19801 tggacgctca gcggctcggc gtccttggac ccatcggggt gcaggaggcg ccgcccgagt
    19861 tcgtgggcgc ggaccggatc ggagcgatcc acataggcga gcagcaggat gcgtccggcc
    19921 tcggtgtact cgtggccggc gtggaggccg agccgctcca gccgttcgag ggcgcgctcg
    19981 cccagcgcga cggcctgccc cagatcgccg acggtgtggt acgaccgggc cagcgcgatc
    20041 accgggggca gccagctcgc cctgcccggg tcgcgctcgg cctgctcgcg cagctcctcg
    20101 aacagctcga tcgcgcggtc ggtgcggccc agttcctcaa gggcgcgggc gcggcccagt
    20161 cgggcgcggg ccgtgaggtc ggggtcgtcg ctgcgggcga tcacctcgtc gaacccggcc
    20221 tcggccgtgg cggggtcgcc gcgcagcagc gccagatggg cgtgccgctc ccgcacctcg
    20281 agatgggcgc gctgctccgg ctcgacgccc tcggcgaggt actcgggagt acagccgaga
    20341 cgctcggcca gcatgcgcag gacggtcggc gtcggcgtgc gcttgcccga ctcgatcaaa
    20401 gagatgtagc tgtcggaaag gtcgtgaccg gcgagctgtg cctgcgacaa gcgtctggtc
    20461 agccgcaggt tgcggacacg ttcgccgacg ttgcctggac ccggcatgtg gactcactta
    20521 gcggaagtaa acaggcggct ggggtgccga catgattgca cattgcgggt tatcacacat
    20581 cgagagcaag gaagcggcag gagaagagac cggccggaag gcccgcgcga acggcgcttc
    20641 ggtgagattc accggttcgc gccggcgggc cctcccgtcg atcgcgacgt ctgtcattcg
    20701 ccgacggtat ccgaccgtcc gggcaagatc gcagagtccg ccgatat
//
