LOCUS       NZ_BMRD01000002        22148 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Actinomadura citrea strain JCM 3295 sequence02, whole genome shotgun
            sequence.
ACCESSION   NZ_BMRD01000002
VERSION     NZ_BMRD01000002.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Actinomadura citrea
  ORGANISM  Actinomadura citrea
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 692488)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: BGI assembly pipeline
            Genome Coverage                   :: 127X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014648455.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 03:26:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,339
            CDSs (total)                      :: 8,265
            Genes (coding)                    :: 8,175
            CDSs (with protein)               :: 8,175
            Genes (RNA)                       :: 74
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 90
            CDSs (without protein)            :: 90
            Pseudo Genes (ambiguous residues) :: 0 of 90
            Pseudo Genes (frameshifted)       :: 12 of 90
            Pseudo Genes (incomplete)         :: 83 of 90
            Pseudo Genes (internal stop)      :: 3 of 90
            Pseudo Genes (multiple problems)  :: 8 of 90
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:33:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 126884
            Orig. end                         :: 149032
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMRD01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22148
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22148
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22148
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12148](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12148
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(658..672)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.1"
                     /tool="antismash"
     gene            707..1903
                     /locus_tag="IEZ14_RS05275"
                     /old_locus_tag="GCM10010177_10660"
     CDS             707..1903
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019633326.1"
                     /locus_tag="IEZ14_RS05275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_10660"
                     /product="CdaR family transcriptional regulator"
                     /protein_id="WP_218935368.1"
                     /transl_table=11
                     /translation="MTRDKTPALRVAGRPMAAHLRVRAPLLTRRVVARLLAELPVYAEL
                     PQEEVAGDIAGIVQHSLRQFADVLERRRPARAADFARQRDSAALRAEEGVPLDAILAAY
                     QIGAAMAWEELTTGAEPADLPAFQEALGYFLDFQRLLTSAVSAAYLEVRQILDSQEHGG
                     RHALMTALLAGDTAGHRPAPRYAVLALAFGPHPDEAGSGQRARIAARRKIRRVRTALDA
                     VADEPALTALDASGGTALLPFSSGWEALHDLVAGAAKAADIEVTAAAEIIGPAGVPGAV
                     AQTAEIMDLVRRAGRPPGLYRLADVLLDYQLSRPSGALAALAALLAPLDRRPDLLSTLE
                     RYLAFDLDRRATGAALHVHPNTVAYRIRRISALTGLDPGRPGDLQLLNAALVARRSLH"
     gene            complement(1946..2131)
                     /locus_tag="IEZ14_RS05280"
                     /old_locus_tag="GCM10010177_10670"
     CDS             complement(1946..2131)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEZ14_RS05280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010177_10670"
                     /product="hypothetical protein"
                     /protein_id="WP_179837080.1"
                     /transl_table=11
                     /translation="MSSAVRRTWRRLVQSYNLLCAREDATARGVSIPSGVWACDHCHAP
                     HLELATLKHHLRTEHA"
     gene            complement(2215..3078)
                     /locus_tag="IEZ14_RS05285"
                     /old_locus_tag="GCM10010177_10680"
     CDS             complement(2215..3078)
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013358.5"
                     /locus_tag="IEZ14_RS05285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_10680"
                     /product="acetate uptake transporter family protein"
                     /protein_id="WP_179837081.1"
                     /transl_table=11
                     /translation="MARRREHQSAPMPGEHTGSAMPAEGMETPAHGAAAPAHGAAMAPP
                     RGADQAGEHALWEDRTRVFLQPIAAPSILGLFGLAAAAMMVGAWQAGWYGGAGTPLILW
                     PFVLTFGGVAQLLAGMWGYRARDGVATAMHGMWGAFFIGWGLLFLLVSIGAAPVALAPV
                     LGTSFQGFAFWFIPLAVITGLGALAALGENLMTALVWGCLAVGAGFTAAGFWAGSTWPL
                     DVGGWLFVAAAVVALYAAAAMMFVNSFGRTILPTGMIRRGANMPGGRGVRPLEYRYGEP
                     GVKIGQ"
     gene            complement(3319..3732)
                     /locus_tag="IEZ14_RS05290"
                     /old_locus_tag="GCM10010177_10700"
     CDS             complement(3319..3732)
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013868.5"
                     /locus_tag="IEZ14_RS05290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_10700"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_179837082.1"
                     /transl_table=11
                     /translation="MTVWRITGGEGAPDPGAREAARYDIVEHDSALLRITAASGVSRVL
                     LAGEVDVSNTAAVAHALRAVHERGSGDLHADLSGVEFMDVAGLRAFSEAARALHDRGRL
                     LVLHGVPPHIERLFTLIGWHTTPGLEIHCPPPR"
     gene            3856..4101
                     /locus_tag="IEZ14_RS05295"
                     /old_locus_tag="GCM10010177_10710"
     CDS             3856..4101
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012851227.1"
                     /locus_tag="IEZ14_RS05295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_10710"
                     /product="DUF2630 family protein"
                     /protein_id="WP_179837083.1"
                     /transl_table=11
                     /translation="MDEKAILERINDFIEEEHALRQAHERAETSNAEAQARLRDLEVAL
                     DQCWDLLRQRRARLAAGQNPDDAQVRPAGEVEGYRQ"
     gene            complement(4117..5772)
                     /locus_tag="IEZ14_RS05300"
                     /old_locus_tag="GCM10010177_10720"
     CDS             complement(4117..5772)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR00795.1"
                     /locus_tag="IEZ14_RS05300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_10720"
                     /product="L-lactate permease"
                     /protein_id="WP_179837084.1"
                     /transl_table=11
                     /translation="MYQQVLDPVADSLGWSSLVAALPLAVLFVLLGGVRMRAWPASLIA
                     LAVALAVAVWTYGMPADQALLAASEGAAFGFYPILWIVINALWVYNITVATGHFDVLRR
                     SFAQVSDDNRLQAVLIAFSFGALLEALAGFGTPVAVTSVMLIALGFPPLKAAVLALTAN
                     TAPVAFGAMATPILTLGKVTGESSDTLGAMVGRQTPILALFVPLVLVVIVDGRRGLRET
                     WPVALLCGAAFGVAQYVTANFISVPLADVVASLVSAAAVVLAVRLRPSAAPARPAPVAG
                     GAADEPTPEFAARVEGRDGGPDGDSRAEVARAYAPYAIIIAVFVVCQIGPVKDLLDRAT
                     RTFSWPGLHLTGPSGKPLALPTFTFNYLTTPGTQMLVAGLITMAALGVGLRRALGAYRT
                     TLVQLRWAIITVMAVLALAFVMNASGQTVTLGTWMAGAGGAFALLSPILGWLGTAVTGS
                     DTSSNSLFGSLQVTAANKADLSTVLMAATNSSGGVLGKMVSPQNLAIAAAAVGLDGREG
                     DIFRRVVLWSLLFLAGMCLLSGLQSTAVLGWMVP"
     gene            complement(5868..7925)
                     /locus_tag="IEZ14_RS05305"
                     /old_locus_tag="GCM10010177_10730"
     CDS             complement(5868..7925)
                     /GO_function="GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1293: aldehyde oxidase and xanthine dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009080773.1"
                     /locus_tag="IEZ14_RS05305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_10730"
                     /product="xanthine dehydrogenase family protein
                     molybdopterin-binding subunit"
                     /protein_id="WP_179837085.1"
                     /transl_table=11
                     /translation="MTDRLEGREKVTGTARYAFEYPVRNAAYAAAVQASVGKGQVRSVD
                     AEAALRLPGVLAVLSCENAPELSDTSDGELALFQSRTVSFRGQFVAAVVAETLETAREA
                     ARLLRVEYAGEAPDVRLRADHPGLYKPDKVNPVFPADTEQGEPEKAFADSAVRVDAVYT
                     TPAEHNNPMEPHATIAQWNEDGTLTLYDSNQGASTVQATIAKVFGLDPSRVHVVSPHVG
                     GGFGSKGMPRPNVVLAAMAARAVGRPVKFAVPRQQMFATTGYRTPTIQRLRLGADEDGR
                     LNAILHEVTEQTSTVKEFAEQTATPTRILYQAPHRLTSHRVVALDVPTPSWMRAPGETP
                     GMYALETAMDELAVAAGIDPVELRVRNDTDREPESGLPFSSRNLVACLREGSERFGWAG
                     RAPEPGARREGRKFVGMGVAASTYPAYQRPNQATARAEPDGTFTVRIAAADIGTGARTA
                     LALIAAETLKEDLADVRMEIGDSAFPRASVAGGSAGTAGWGTAVVRACEALRGKLNGAV
                     PPGGIEASADTGEELRARAEYARHAFGAQFAEVEVDADTGEVRVRRMLGVFAAGRIINP
                     TTARSQFIGGMTMGVGMALMEQSVMDREFGDYLTRDLAQYHVPVCADIRDIDAAWVEES
                     DPHLNPMGAKGIGEIGIVGAAAAVGNAVHHATGIRVRDLPITPARLLQAL"
     gene            complement(7922..8896)
                     /locus_tag="IEZ14_RS05310"
                     /old_locus_tag="GCM10010177_10740"
     CDS             complement(7922..8896)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630123.1"
                     /locus_tag="IEZ14_RS05310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_10740"
                     /product="xanthine dehydrogenase family protein subunit M"
                     /protein_id="WP_179837086.1"
                     /transl_table=11
                     /translation="MRPFAYERATSAEDALRRHQDGAVYLGGGTNLVDLMRLGVEEPAR
                     LVDVAHLPYDQIELRPDGSLVIGAAVTNSAVAADRTVREGHPVLAQAVLAGASGQVRNL
                     ATVGGNLLQRTRCSYFQDAAKPCNKRTPGSGCPAREGEHHNLAILGWSDACVATHPSDM
                     AVALAALDASIRIRGRGGERTIPIEDLYRLPGDEPQRDTTLEPGDLVTAVEVPALGVPS
                     RYRKVRERASFAFALVSIAAALDVGDGRVRDVRLALGGVAHKPWRARRAEEALRGAEAT
                     EESFLRAAEAELEAAEPLRDNAYKVPLARNLIVRTLTELGEES"
     gene            complement(8893..9438)
                     /locus_tag="IEZ14_RS05315"
                     /old_locus_tag="GCM10010177_10750"
     CDS             complement(8893..9438)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009080775.1"
                     /locus_tag="IEZ14_RS05315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_10750"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_218935369.1"
                     /transl_table=11
                     /translation="MDSEATPVRADVTLVVNGAEHRLNVDTRASLLDVLREQLGLTGSK
                     KGCDHGQCGACTVLLDGRRVNGCLALAVAHDGADVVTVEGLARDGELSPVQEAFIENDA
                     FQCGYCTPGQLCSATGMLDEAERGWPSVVTGDLRADPVLDDDEIRERMSGNLCRCGAYV
                     GIVAALKQAARRREGAEA"
     gene            complement(9517..9888)
                     /locus_tag="IEZ14_RS05320"
                     /old_locus_tag="GCM10010177_10760"
     CDS             complement(9517..9888)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018980.5"
                     /locus_tag="IEZ14_RS05320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_10760"
                     /product="phage holin family protein"
                     /protein_id="WP_179837087.1"
                     /transl_table=11
                     /translation="MSESRKPAAAGDPLEQNLVLARRVVEAAQQEMIDKARQRIPALRL
                     GAVAGAFGVMATAATYRMNVLLLEKKLPPELASFITAAVYGGGAGAAAMAASRKWKGLP
                     APLPTDTARQVVEILTDND"
     misc_feature    9936..9949
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.06"
                     /tool="antismash"
     misc_feature    complement(9946..9956)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            10001..12148
                     /locus_tag="IEZ14_RS05325"
                     /old_locus_tag="GCM10010177_10770"
     CDS             10001..12148
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012886878.1"
                     /locus_tag="IEZ14_RS05325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_10770"
                     /product="germacradienol/geosmin synthase"
                     /protein_id="WP_179837088.1"
                     /sec_met_domain="T1TS (E-value: 5.5e-78, bitscore: 258.5,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQPFELPDFYVPYPARLNPHLEGARRHTMAWAREMKMLDADRDPG
                     TPDIWDEPALEAMDYALLCAYTHPDCAAPELDLVTDWYVWVFYFDDHFLEVLKKPRDQE
                     GARTYLDRLPLFMSLDPPEPVNAVERGLADLWARTVPARSDAWRRRFSMSTLNLLRESL
                     WELSNISTGRIPNPVEYIEMRRKVGGAPWSADLAEHAAGVEIPERVVATRPLRVLKDTF
                     SDGVHLRNDIFSYQRETESEGEVNNSVLVMERFLSVAPQVAADTVNDLLTSRLRQFENT
                     AVTELPHVFEDHGLDPAERAGVAAYVKALQDWQSGGHEWHLRSSRYMNDRSLGMSAARI
                     PALVKSARISLPHVPFQRVGPTPLPSFDIPYAARVNPHRERAGRNLLAWAREMGMFSPH
                     PRTPVPVWSPDRLAGMVLEVCAASLDPDADPEALDLAVQWLACGTFGDDFFPAVFNRDR
                     DMAGAKAFNARVPRFMPLDCGAAPAPENPFEAGLADLWPRTAGPMDDKGRREFRAAVEH
                     MVESWVWELNNHLQSRVPDPVDYIEMRRHTFGSELTMSLARIGRADEIPQHVFETRTLR
                     EIDASAMDVACLLNDCFSYQKEIEYEGELNNGVLAVGNFFGCGRDEALPIVADLIASRR
                     RQFEHLAAGELPALCDRLDLDDAARAALSSYVEELRDWMAGILKWHRETDRYDEREPVL
                     RLPRPTGLGMSAFHLFARAAR"
     assembly_gap    12153..12378
                     /estimated_length=226
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            12398..13063
                     /locus_tag="IEZ14_RS05330"
                     /old_locus_tag="GCM10010177_10780"
     CDS             12398..13063
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017572678.1"
                     /locus_tag="IEZ14_RS05330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_10780"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_229809959.1"
                     /transl_table=11
                     /translation="MPSPLRKSTSQESHPPDDRRRRFEDVYAANRARILGYALRRTSDP
                     QDAADVLAETFLTAWRRLDDVPPGDQARLWLYGVARRVLANHHRGERRRSALAADLGSR
                     LRDGLAVQDPSGDGPTGVGAAFRGLPESDRELLALVGWEGLDHGEIATVLGCSRNAVRI
                     RLHRARRRFARALASMDADAPAAPAPAASLRAASTPATSLHAASLPAKGRRIPNGDPT"
     gene            13060..14010
                     /locus_tag="IEZ14_RS05335"
                     /old_locus_tag="GCM10010177_10790"
     CDS             13060..14010
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEZ14_RS05335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010177_10790"
                     /product="hypothetical protein"
                     /protein_id="WP_179837090.1"
                     /transl_table=11
                     /translation="MNRDIDPLIGGLASVTDRQAGTLLPEDAATALADRITATAVPSAP
                     ARGRRSPVMLIGLPLAAAGIAAAAVTAVVTTRDGGPGSTPGVTPTSPRVVLAAALTFTR
                     KGGYIDVRVRDPLADPKRYQEEFAAHGLKVTLSMVPASPSIVGTVVAMETSENTAERDV
                     TTITARGGCETGGGGDVCPVGVRIRTGYKGTASITFGREARPGEQYNSSAPATAPGEVM
                     HGMTYRKHRVGEVLAALRKRHVTVPEYRAMEGNVSNVLKPGQVPPTWYVHSATPWAKNQ
                     VLLFVGPHPTEDAGGAPPASAPPGAPAAPSATPTS"
     gene            complement(14061..15260)
                     /locus_tag="IEZ14_RS05340"
                     /old_locus_tag="GCM10010177_10800"
     CDS             complement(14061..15260)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012894313.1"
                     /locus_tag="IEZ14_RS05340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_10800"
                     /product="MFS transporter"
                     /protein_id="WP_179837091.1"
                     /transl_table=11
                     /translation="MSVETASPRVSVSGGRLPLGVYLLAFSLFAMGSAEFLLAGVLPEI
                     ADDLGISLSSAGALISAFAVGVVVGGPPFAILTLHLPRRTTLVATQVVFAVSVTAGLVI
                     DGYAVLLASRFLCGLAYAGYWAVAAVTAIGLVTSDRTARASGVVVSGLGLAMIAGGPAG
                     ALLSYFTGWRGGFWGVVVLTAAGAVLSLLAVPATGADAKPSVRGELRTMRRPQLWVVYA
                     ATVLSTAAYMISFNYLAAFLTDVTGIPGVWVPAILALFGVGAFIGLSVGGRIADRRPTH
                     ALMAGALGISASSVLLAVLSGHATAVVPLVLLLGVAGFVLNPAIYGRVFAIASEAPTLA
                     GAATVSAFQLGISLVPVLAGAAMNAGAGLTAVPWIGAGLAAAIVPTVLLDRTLSRRAKI
                     "
     gene            complement(15257..16204)
                     /locus_tag="IEZ14_RS05345"
                     /old_locus_tag="GCM10010177_10810"
     CDS             complement(15257..16204)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012894312.1"
                     /locus_tag="IEZ14_RS05345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_10810"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_179837092.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 6.5e-31, bitscore:
                     102.9, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDAEYDVVVVGAGAAGLSAALVLARARRRVAVVDAGEPRNAPAA
                     HMQGFLSRDGMRPAALLEVGRAEVTGYGAALIDARVEHVDPGFTVRLVGGAVLGARRLV
                     VATGLRDELPGIPGVAERWGRDVLHCPYCHGYEFRDRPMGVLGTSPGAVHQALLLRQWS
                     DDVVLFVHTLELDEEEHERLTARGVRLVDGEIKRVVAENDGVRGVELADGRMVPRRVVF
                     LFPRMVPHDALLTALGCAVEDRRVVTDRTGRTTVPGVWAVGNVADPRAQVVTAAGMGSA
                     AAIAVNADLLDEDVHQAVDQGRAVERGRVGGGGR"
     gene            16297..16896
                     /locus_tag="IEZ14_RS05350"
                     /old_locus_tag="GCM10010177_10820"
     CDS             16297..16896
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012894311.1"
                     /locus_tag="IEZ14_RS05350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_10820"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_179837093.1"
                     /transl_table=11
                     /translation="MPHPSAIADALAEVGPRLKRLRNERNVTLAELSEATGISKSTLSR
                     LESGQRRPSLELLLPISHAHQVPLDELVGAPEVGDPRVRLTPRRVNGNTVLPLTRQPGP
                     IQSYKMVLPAARRVPDLCTHEGYEWLYVLSGRLRLVLADHDLVLGPGEVAEFDTRLPHW
                     FGTTGEGPVEVLSLFGRQGERLHIRARPRPRQEPAS"
     gene            complement(16997..17524)
                     /locus_tag="IEZ14_RS05355"
                     /old_locus_tag="GCM10010177_10830"
     CDS             complement(16997..17524)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017595489.1"
                     /locus_tag="IEZ14_RS05355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_10830"
                     /product="NADAR family protein"
                     /protein_id="WP_179837094.1"
                     /transl_table=11
                     /translation="MDVAELTRLQEQGTRLRFLFFWGHQTPGRGYLSQWWPSPFTVGGV
                     TYATAEHYMMAEKARLFGDEETAAAIVAASHPRRAKDLGRRVRDFDERTWRDNRVTIVT
                     KGGEAKFAQNKDLRDYLAGTRDRILVEASPLDRVWGIGLTADDPRTEHPASWQGENLLG
                     FALMTVREALAS"
     misc_feature    17632..17647
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.64"
                     /tool="antismash"
     gene            17720..17848
                     /locus_tag="IEZ14_RS42295"
                     /old_locus_tag="GCM10010177_10840"
     CDS             17720..17848
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEZ14_RS42295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010177_10840"
                     /product="hypothetical protein"
                     /protein_id="WP_268247751.1"
                     /transl_table=11
                     /translation="MDNALANPRRTKIDAWPEWRPAEPDSERPAEADVSEDELAAH"
     gene            complement(17939..18568)
                     /locus_tag="IEZ14_RS05360"
                     /old_locus_tag="GCM10010177_10850"
     CDS             complement(17939..18568)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017596625.1"
                     /locus_tag="IEZ14_RS05360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_10850"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_179837095.1"
                     /transl_table=11
                     /translation="MSENDPSPEPESTDGRLLRGARARRTITRHAVDVASLEGLNGLSF
                     GRLATDLRVSKSGIQTLFRTRQNLQLATVGAARELFADAVVRPAQAAPAGAARLRALVG
                     YWIEYAEKPLFTGGCFWAANLPDFDSRPGPVRDTLAQQHRRWLSLIAGELRHAVDAGEI
                     APLDPDLAAFQTDAVLNAANTALRLGDQDAAGKARRVVDALLTRPV"
     misc_feature    18581..18594
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.65"
                     /tool="antismash"
     gene            18656..19105
                     /locus_tag="IEZ14_RS05365"
                     /old_locus_tag="GCM10010177_10860"
     CDS             18656..19105
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF07366"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019013.5"
                     /locus_tag="IEZ14_RS05365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_10860"
                     /product="ester cyclase"
                     /protein_id="WP_218935370.1"
                     /sec_met_domain="PF07366 (E-value: 2.3e-16, bitscore: 55.1,
                     seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDGDRMFELAQALAAAKSRQDVPAAMKLLHPEMVLESPAFGTTAR
                     GPAENEKALRRFFASFPDYDVVLQGHAASGEALACWGTVRMTMTGDRFGAEPNGRRAEL
                     PVFIRFGFEDDLIAAEYFFFDLSELCAQSGVSTDAVRRTLFGSAG"
     misc_feature    18663..18678
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.61"
                     /tool="antismash"
     misc_feature    complement(18664..18677)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.65"
                     /tool="antismash"
     gene            19134..19628
                     /locus_tag="IEZ14_RS05370"
                     /old_locus_tag="GCM10010177_10870"
     CDS             19134..19628
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023010.5"
                     /locus_tag="IEZ14_RS05370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_10870"
                     /product="DUF3237 domain-containing protein"
                     /protein_id="WP_179837096.1"
                     /transl_table=11
                     /translation="MPADPRVRDVDGIRTEFLFDIVVDLDPPLDFGRGPVGRRVLFGSA
                     GGTFEGPALRGEVLPGGGDWALFRSDGTMLLDVRLTLRTDDGALLHMTYGGRYTTPPGL
                     RAEMADPAARHRVDPSRYYFRTNPLFETGAEQYTWLNDVVCVGSGYLVQDGIAYKVFQV
                     L"
     gene            complement(19651..20775)
                     /locus_tag="IEZ14_RS05375"
                     /old_locus_tag="GCM10010177_10880"
     CDS             complement(19651..20775)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1268: mandelate racemase/muconate lactonizing enzyme"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024771.5"
                     /locus_tag="IEZ14_RS05375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_10880"
                     /product="mandelate racemase/muconate lactonizing enzyme
                     family protein"
                     /protein_id="WP_179837097.1"
                     /transl_table=11
                     /translation="MKIEKIETFCVALPTRRSFGVSGGAVAVAGRPSLRVLVKVSAEGA
                     HGWGEATPIPAWTYETAESIVTTIDRYLAPAITGRPAWDLDGVTTAFDRAVNRGFSIGA
                     PLAKSAVDVALHDLLGRAAGVPLGVMWGRRRRETIDLGWIVSGRSSAEVADSVAEGRGL
                     GYRAFKVKVGLGPEDADVVEAVRLHAGDAAALWVDANQGYTVRSALALARRLEDLGVTA
                     FEQPLPANDIVGLRRLRDACPIPVALDESLRHPSDLATFVRLDAVDVAIAKVQRTGGLT
                     LSRRLCALAEDCGVALMGSGLTDSDLGLAASLHLFSAFGIDTPVDLNGRQFIDSPYAGP
                     TVEIRDGTARVPDAPGLGVEVDERTVRDLAVDVL"
     misc_feature    20757..20766
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.81"
                     /tool="antismash"
     gene            complement(20806..21864)
                     /locus_tag="IEZ14_RS05380"
                     /old_locus_tag="GCM10010177_10890"
     CDS             complement(20806..21864)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019631477.1"
                     /locus_tag="IEZ14_RS05380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_10890"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_179837098.1"
                     /transl_table=11
                     /translation="MTEAAEGERTGDRAYVTLQDVARDAGVSLATASRVLNGTSQVRAD
                     LRERVLAAAAELSYTPNAHAQALASSSSKSVGVVCHDVSDPYFAAVARGVMRTAAEYGM
                     LVMLASTFRDPAREVEYVAMLRAQRARAILLIGSGFEDREWERAMAAELDPYQRTGGRV
                     AVLSRHRSLKVDAILPQNREGAAALARALLDLGHRRFGVLTGPRALTTVHDRLGGFTEA
                     LADAGVRVAPEHIVEAPFTRDGGYRAAAELLRRENRPTCVFAVTDVMAVGALAALRDHG
                     VLVPGEMSLAGFDDISIVRDLTPALTTVALPLNAMGERVMGLALREPATRRSRIERVAG
                     EVVLRASTAPPG"
     misc_feature    complement(21016..21018)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(21957..21968)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.99"
                     /tool="antismash"
ORIGIN
        1 cgggccttcg gggagcgggc gcggatgccg tccaggacgg cggacagctt cgggccgaag
       61 tcgcgggtgc gctgggccac ctgctcctcg aactcgccct tgcacggggt ggcggtgggg
      121 tcgagggtgg cgcagtcctg ggcgatgccg acgaggccga cgtcgttgcc gccgatggtg
      181 agggtcacca gcgcggtgga cgcggtgagc gcgtcgagct gcggcgggac ggtccccgtg
      241 tcgacaccgc cgacgctggt gctctgcgac tgggtcatgt gggtggtctt ggcgccgctg
      301 caggtgacgt cccggagcgc ggcgccgagc cgggacgcca gctcgtgcgc gtagttgtgg
      361 gtggagcgcc cgcagccgat cgggccggtg atgtccggga tgagcgggcc ggacgccatc
      421 gagtcgccga gcgcgacgta ctcctgcgcg gccgccgccg cgggcaccgc cgtcccgccg
      481 agggccgccc ccgccaggac gatcgcgccg acggcgcccc tgacgacccg gcccctgccg
      541 cgccggcgtg cggcgactcg cgtgacgacc cggccggtgg acgggcggcc gttgaacaga
      601 cgcttcatga gctgactccc ggcgtcatgg acgatgtcgc cgtgatcgtc cagaatctgg
      661 acacgccgtt caattggcgt ggggacagac tcttccggga gccgttgtga cgcgggacaa
      721 gacgccggcg ctgcgggtgg cgggccggcc gatggcggcc catctgcggg tccgcgcgcc
      781 gctgctgacc cgccgggtcg tggcgcggct gctcgccgag ctgcccgtct acgccgaact
      841 gccgcaggag gaggtcgccg gggacatcgc cgggatcgtc cagcacagcc tgcggcagtt
      901 cgcggacgtc ctggagcggc gccggccggc ccgcgcggcc gacttcgccc ggcagcgcga
      961 ctcggcggcg ctacgggccg aggagggcgt gccgctggac gcgatcctcg ccgcctacca
     1021 gatcggggcg gccatggcct gggaggagct gaccaccggg gccgagcccg ccgacctgcc
     1081 cgccttccag gaggcgctcg gctacttcct cgacttccag cggctgctga cctcggccgt
     1141 cagcgccgcc tacctggagg tgcggcagat cctcgacagc caggagcacg gcggccggca
     1201 cgccctgatg accgcgctgc tggcagggga caccgcgggg caccgcccgg cgccccggta
     1261 cgccgtcctg gcgctggcgt tcggcccgca tccggacgag gccggctcgg gccagcgggc
     1321 ccggatcgcc gcccgccgca agatccgccg cgtccggacc gccctggacg ccgtcgccga
     1381 cgagcccgcc ctcaccgccc tggacgcatc gggagggacg gctctactgc ccttctcctc
     1441 cggctgggag gccctgcacg acctggtcgc gggcgcggcg aaggcggccg acatcgaggt
     1501 gacggccgcc gcggagatca tcggcccggc gggcgtgccg ggcgccgtcg cccagaccgc
     1561 cgagatcatg gatctggtgc gccgggcggg ccgcccgccc ggcctgtacc ggctcgccga
     1621 cgtcctgctg gactaccagc tgagccgccc gagcggcgcg ctcgccgcgc tcgccgccct
     1681 gctggcgccg ctcgaccgca ggccggatct gctgagcacc ctggagcgct acctggcgtt
     1741 cgacctggac cgccgcgcga ccggtgcggc cctgcacgtc cacccgaaca cggtcgccta
     1801 tcgcatccgc cgcatcagcg ccctcaccgg actggacccg ggccgccccg gcgacctcca
     1861 gctgctgaac gccgccctgg tggcccgccg ctccctgcac tgatcccatc cggccggatc
     1921 cccgggagac cggggacggg cggggtcagg cgtgttcggt gcggaggtgg tgcttgagcg
     1981 tggccagttc gaggtgcggc gcgtggcagt ggtcgcaggc ccagactccg ctgggaatgg
     2041 agacgccgcg cgccgtcgcg tcctcgcgcg cgcacagcag gttgtaggac tggacgaggc
     2101 gtcgccacgt ccgccggacc gccgatgaca ttcccgctcc ccctccgagc ccggtttcca
     2161 accttcttgg gctcagcata gggtaacggg aatgtcaagg cgaaacgccg gacatcactg
     2221 cccgatcttc acacccggct caccgtaccg gtactccagg ggccggactc cccggccgcc
     2281 gggcatgttg gcgccccggc ggatcatgcc cgtgggcagg atcgtccgtc cgaagctgtt
     2341 cacgaacatc atcgcggccg ccgcgtacag ggcgaccacc gccgccgcga cgaacagcca
     2401 gccgccgacg tccagcggcc aggtcgagcc ggcccagaat ccggcggccg tgaagcccgc
     2461 gccgacggcc aggcagcccc acaccagggc cgtcatcaga ttctcaccga gcgcggcgag
     2521 cgcgcccagg ccggtgatca ccgcgagtgg aatgaaccag aacgcgaagc cctggaagga
     2581 ggtaccgagg accggcgcca gcgccacggg cgcggcgccg atgctcacca gcaggaacag
     2641 caggccccag ccgatgaaga acgcgcccca catgccgtgc atcgcggtgg ccacgccgtc
     2701 gcgcgcccgg tagccccaca tgccggccag cagctgcgcg acgccgccga aggtcagcac
     2761 gaacggccac aggatgagcg gggtgccggc gccgccgtac cagccggcct gccacgcgcc
     2821 caccatcatg gccgccgcgg cgagcccgaa cagcccgagg atcgacggcg ccgcgatggg
     2881 ctgcaggaag acgcgggtgc ggtcctccca gagcgcgtgt tcgccggcct ggtccgcgcc
     2941 ccgcgggggc gccatcgccg cgccgtgcgc cggcgcggcc gcgccgtgcg ccggcgtctc
     3001 catgccctcc gcgggcatcg ccgatcccgt gtgctcgccg ggcatcggcg cggattggtg
     3061 ctctctacgc cttgccatga gatccccctc tgaatcggag agctgtaagc ccctcctaac
     3121 cgtgttcaag caggtcaaac ggcatatgac cgtttcctga agaggttcgc gtttgcaccc
     3181 ggcacccttt gccaggcgct gacacgggca tggcgatccg gtggcccggc ggtccgggac
     3241 gcgggtcagg tggctcggcg atcgggcggc tcagtgttcc gacggctcag tgttccggcg
     3301 gcccggtcct ccggcggctc agcggggcgg cgggcagtgg atctcaaggc cgggcgtggt
     3361 gtgccagccg atcagcgtga acagccgctc gatgtgcggg gggaccccgt gcaggacgag
     3421 gaggcggcca cggtcgtgca gggcgcgggc ggcctcgctg aaggcgcgca gacccgcgac
     3481 gtccatgaac tcgacccccg acaggtcggc gtgcaggtca ccggacccgc gttcgtggac
     3541 ggcgcgcagg gcgtgcgcga ccgcggcggt gttggagacg tcgacctccc cggcgagcag
     3601 cacccgggac acgcccgacg cggccgtgat gcgcagcagc gcggagtcgt gctcgacgat
     3661 gtcgtagcgg gcagcctccc gcgcaccggg gtcgggggcg ccctcgccgc cggtgatccg
     3721 ccagaccgtc atctgctcct caccctcaac gggggcgccg ccgctaccgt gcgcggcccc
     3781 gtatatgcaa ggctctcacc tgtcgggacc ttctggaccc caccagagcg gaaaaccacg
     3841 atcggaagcc atttcatgga cgagaaggcg atcctggaac gtatcaacga tttcatcgag
     3901 gaggaacacg ccctccggca ggcgcacgag cgggccgaga cctccaacgc cgaggcccag
     3961 gcgcggctgc gggacctgga agtggccctc gaccagtgct gggatctgct gcggcagcgg
     4021 cgggcccgcc tcgcggcggg acagaacccc gacgacgccc aggtccgtcc cgccggcgaa
     4081 gtggaaggct accggcagta gcgcctcacg ggcccgtcac gggaccatcc agccgagcac
     4141 ggcggtggac tgcaggccgg agagcaggca catcccggcg aggaacagca ggctccacag
     4201 cacgacgcgg cggaagatgt cgccctcgcg cccgtccagg ccgacggccg ccgcggcgat
     4261 ggcgaggttc tgcggcgaca ccatcttgcc gaggacgccg ccggagctgt tggtcgccgc
     4321 catcaggacc gtcgacaggt cggccttgtt cgcggcggtg acctgcaggg agccgaacag
     4381 cgagttggac gaggtgtccg atccggtgac ggcggtgccg agccagccga ggatcggcga
     4441 cagcagcgcg aacgcgccgc ccgcaccggc catccacgtc ccgagcgtca cggtctgccc
     4501 ggaggcgttc atcacgaagg ccagcgccag gacggccatg accgtgatga tcgcccacct
     4561 gagctgaacg agggtcgtcc ggtaggcgcc cagggcccgg cgcaggccga cgccgagggc
     4621 ggccatggtg atcagcccgg cgacgagcat ctgcgtgccg ggcgtggtca ggtagttgaa
     4681 ggtgaaggtc ggcagggcca gcggcttgcc ggacgggccc gtgaggtgca ggcccggcca
     4741 ggagaacgtc cgggtcgccc tgtccaggag atccttgacc ggcccgatct ggcagacgac
     4801 gaagaccgcg atgatgatcg cgtagggcgc gtaggcgcgg gcgacctcgg cgcgggagtc
     4861 cccgtccggt cccccgtccc gtccttcgac gcgggcggcg aactcggggg tcggctcgtc
     4921 cgccgcaccg cccgcgaccg gggccggcct cgccggcgcc gccgacggac gcagccggac
     4981 ggcgaggacg acggccgcgg ccgagaccag cgaggccacg acgtcggcga gcggcaccga
     5041 gatgaagttc gccgtgacgt actgggcgac gccgaacgcg gcgccgcaca gcagggcgac
     5101 gggccaggtc tcgcgcaggc cgcgccgccc gtccacgatg acgacgagga cgagcgggac
     5161 gaacagggcg aggatcgggg tctgccgccc caccatggcg ccgagcgtgt cgctggactc
     5221 gccggtgacc ttgccgagcg tgaggatcgg cgtcgccatc gcgccgaacg cgacgggcgc
     5281 ggtgttggcg gtgagggcca gcacggcggc cttgagcggc gggaagccga gcgcgatcag
     5341 catgacggag gtgaccgcga ccggcgtgcc gaacccggcc agggcctcca gcagcgcgcc
     5401 gaacgagaag gcgatcagca ccgcctggag cctgttgtcg tcgctgacct gcgcgaacga
     5461 gcggcgcagc acgtcgaagt ggccggtggc gacggtgatg ttgtagaccc agagggcgtt
     5521 gatgacgatc cacaggatcg ggtagaagcc gaacgcggcg ccttcggagg cggcgagcag
     5581 cgcctggtcg gcgggcatgc cgtacgtcca gacggcgacc gccagcgcga cggccagcgc
     5641 gatcagggac gccggccacg cgcgcatgcg cacgccgccg agcaggacga acagcacggc
     5701 cagcggcagc gcggcgacca gggagctcca gccgagcgag tcggcgacgg gatcgaggac
     5761 ctgctggtac acggcgatca cctcgcgggg tagtggtcgc ccccgagcac gtgatcctta
     5821 cccgtcccga tgacggagat caccttgata gtgaactttt ccctcggtca gagggcctgg
     5881 agaagcctgg ccggggtgat gggcaggtcc cggacgcgga tgccggtcgc gtggtggacg
     5941 gcgttgccga cggccgccgc cgccccgacg atgccgatct cgccgatgcc cttggcgccc
     6001 atcgggttca ggtgcgggtc ggactcctcc acccacgcgg cgtcgatgtc gcggatgtcg
     6061 gcgcagaccg ggacgtggta ctgggcgagg tcgcgggtga ggtagtcgcc gaactcccgg
     6121 tccatgacgc tctgctccat cagcgccatc ccgacgccca tcgtcatccc gccgatgaac
     6181 tgggaccggg ccgtcgtggg gttgatgatc cggccggcgg cgaacacgcc gagcatccgg
     6241 cggacgcgga cctctccggt gtcggcgtcc acctccacct cggcgaactg cgcgccgaac
     6301 gcgtgccggg cgtactcggc ccgggccctg agctcctcgc cggtgtcggc ggacgcctcg
     6361 atccccccgg gcgggacggc gccgttcagc ttgccgcgca gggcctcgca ggcgcgcacg
     6421 acggccgtgc cccagccggc cgtcccggcg gagccgcccg ccaccgacgc ccgggggaac
     6481 gcgctgtcgc cgatctccat cctgacgtcg gcgagatcct ccttcagcgt ctcggcggcg
     6541 atcagggcca gggcggtgcg ggcgccggtg ccgatgtcgg cggcggcgat ccggacggtg
     6601 aacgtcccgt cgggctcggc gcgggccgtg gcctggttgg ggcgctggta ggcgggatag
     6661 gtggacgcgg cgacgcccat accgacgaac ttgcggccct cccggcgggc accgggttcg
     6721 ggggcgcgcc ccgcccagcc gaagcgttcg gagccctcgc ggaggcaggc gaccaggttc
     6781 cgcgagctga acggcagccc gctctccggc tcccggtcgg tgtcgttgcg cacgcggagc
     6841 tcgaccgggt cgatgcccgc ggcgacggcc agctcgtcca tcgccgtttc gagcgcgtac
     6901 atgccgggcg tctccccggg ggcccgcatc caggacggcg tggggacgtc caaggccacc
     6961 acccggtgcg acgtgaggcg gtgcggggcc tggtacagga tgcgcgtggg cgtcgcggtc
     7021 tgctcggcga actccttgac ggtggaggtc tgctcggtca cctcgtggag gatcgcgttc
     7081 agccgcccgt cctcgtcggc gccgagccgg agacgctgga tggtcggggt ccggtagccg
     7141 gtggtggcga acatctgctg gcgcgggacg gcgaacttca cgggacgtcc cacggcgcgg
     7201 gcggccatcg cggcgagcac cacgttcggc cggggcattc ccttggagcc gaaaccgccg
     7261 ccgacgtgcg gcgatacaac gtgcacccgg gaaggatcga gcccgaacac cttcgcgatc
     7321 gtggcctgga cggtcgacgc gccctggttg gagtcgtaga gcgtgagggt gccgtcctcg
     7381 ttccactggg cgatcgtggc gtgcggctcc atcgggttgt tgtgctcggc cggggtcgtg
     7441 tagacggcgt ccacgcgcac cgccgagtcg gcgaacgcct tctcgggctc gccctgctcg
     7501 gtgtccgccg ggaacaccgg gttcaccttg tccggcttgt agaggcccgg atggtcggcg
     7561 cggagccgca cgtccggtgc ctccccggcg tactcgacgc gcagcaggcg ggccgcctcc
     7621 cgggcggtct ccagggtctc ggcgaccacg gcggcgacga actggccgcg gaaggagacc
     7681 gtccgcgact ggaacagggc cagttcgccg tccgaggtgt cgctgagctc gggggcgttc
     7741 tcgcaggaca ggacggcgag caccccgggc agcctcagcg cggcctcggc gtcgaccgac
     7801 ctgacctgcc ccttgcccac gctcgcctgg accgccgcgg cgtaggcggc gttccgcacg
     7861 gggtactcga acgcgtaccg cgccgtcccg gtgaccttct cgcggccctc cagccggtcg
     7921 gtcatgactc ctcccccagc tcggtcagcg tccggacgat caggttgcgc gccagcggca
     7981 ccttgtaggc gttgtcgcgc agcggctcgg cggcctccaa ctcggcctcg gcggcgcgca
     8041 ggaacgactc ctcggtcgcc tccgcgccgc gcagggcctc ttcggcgcgc cgcgcccgcc
     8101 acggcttgtg ggcgacgccg ccgagggcca gccggacgtc ccgcacccgg ccgtcgccga
     8161 cgtccagggc cgccgcgatg gagaccagcg cgaacgcgaa cgacgcgcgc tctcggacct
     8221 tgcggtagcg ggacggcacg cccagcgcgg ggacctccac ggcggtgacg aggtcgcccg
     8281 gttcgagcgt ggtgtcgcgc tggggttcgt cacccggaag ccggtacagg tcttcgatgg
     8341 ggatggttct ctctccaccg cgcccccgga tgcgtatgga cgcgtccaag gcggccagtg
     8401 cgacggccat gtcggacggg tgcgtcgcca cacaggcgtc cgaccagccc aagatcgcca
     8461 gattgtggtg ctcgccctcc cgcgccgggc acccgctgcc cggggtgcgc ttgttgcagg
     8521 gcttggcggc gtcctggaag taggagcagc gggtccgctg gagcaggttg ccgccgacgg
     8581 tggcgaggtt gcggacctgg ccggacgccc ccgcgagcac ggcctgcgcc aggacgggat
     8641 ggccctcgcg cacggtccgg tcggcggcga cggcgctgtt ggtcaccgcc gcgccgatga
     8701 cgaggctccc gtccggccgc agttcgatct ggtcgtacgg aagatgcgcg acgtcgacga
     8761 gcctggccgg ctcctccacg ccgagtcgca tcaggtcgac gaggttggtt ccgccgccca
     8821 ggtagacggc tccgtcctgg tggcgccgca gtgcgtcctc ggcgctggtg gcgcgctcgt
     8881 acgcgaaggg cctcatgcct cggccccctc cctgcgtctc gcggcctgtt tgagggccgc
     8941 gactatgccg acgtaggcgc cgcaccggca caggttgccg ctcatgcgct cgcgtatctc
     9001 gtcgtcgtcg agtacggggt cggccctcag gtcgccggtg acgacgctgg gccagccgcg
     9061 ttcggcctcg tccagcattc ccgtggcgga gcagagctgg ccgggtgtgc agtacccgca
     9121 ctggaacgcg tcgttctcga tgaacgcctc ctggacggga ctgagctccc cgtcccgcgc
     9181 cagcccttcg accgtgacga cgtccgctcc gtcatgggcg acggccaggg ccaggcaccc
     9241 gttcacccgg cggccgtcga gaaggacggt gcaggctccg cactggccgt ggtcgcagcc
     9301 cttcttcgac cccgtcaggc cgagttgctc gcgcagcacg tccaggaggg acgctcgggt
     9361 atcgacgttg agccggtgct ccgccccgtt cacgaccagg gtgacgtcgg cgcgcaccgg
     9421 agtggcttcg ctgtccatgc cggggggcct accccagatc tcccatcggt cacagaacat
     9481 cgacggccgt ccgcacccgc ttccggcggc cggcgatcag tcgttgtcgg tgaggatctc
     9541 cacgacctgc cgggccgtgt cggtcggcag cggcgccggc agccccttcc acttgcggga
     9601 cgcggccatc gcggccgcgc cggcccctcc cccgtacacg gcggcggtga tgaacgacgc
     9661 cagttcggga ggcagcttct tctccagcag cagcacgttc atccggtagg tggccgcggt
     9721 cgccatgacc ccgaaggccc cggccacggc cccgaggcgc agcgccggta tgcgctgcct
     9781 ggccttatcg atcatctcct gctgcgccgc ctcgaccaca cgccgggcga gcacgaggtt
     9841 ctgctccagc gggtcgccgg ccgcggcagg tttgcgcgac tccgacatga cctcggctta
     9901 cccgcagatg gggaggagat tccaggaagc aatatgtcac tttcagtgac tttgcaggtg
     9961 ctgtaggttg ccgaaccgga cccgacagag aggccggttc atgcaaccct tcgagctgcc
    10021 cgacttctac gtcccgtacc ccgcgcgact caacccgcat ctggagggcg cacgccggca
    10081 caccatggcc tgggcgcgcg agatgaagat gctggacgcc gaccgggacc ccggcacccc
    10141 cgacatctgg gacgagcccg cactcgaagc gatggactac gccctccttt gcgcctacac
    10201 gcaccccgac tgcgccgccc ccgaactcga cctcgtcacc gactggtacg tctgggtctt
    10261 ctacttcgac gaccacttcc tggaggtgct caagaaaccc cgggaccagg agggcgcccg
    10321 cacctacctc gaccggctgc cgctgttcat gtcgctcgac ccgcccgaac cggtgaacgc
    10381 cgtcgagcgc gggctcgccg acctgtgggc gcggaccgtc ccggcgcggt cggacgcctg
    10441 gcggcgccgc ttttcgatga gcaccctgaa cctgctgcgc gagtcgctgt gggagctgtc
    10501 caacatcagt accggccgga tcccgaaccc ggtcgagtac atcgagatgc ggcgcaaggt
    10561 cggcggggcg ccctggtcgg ccgacctcgc cgagcacgcc gctggcgtcg agatccccga
    10621 acgcgtggtg gcgacgcggc cgctgcgcgt cctgaaggac accttctccg acggcgtcca
    10681 cctgcgcaac gacatcttct cctaccagcg cgagaccgag tccgagggcg aggtcaacaa
    10741 ctccgtcctg gtgatggagc gcttcctgtc ggtcgcgccg caggtcgccg ccgacaccgt
    10801 caacgacctg ctgacctcgc ggctgcgcca gttcgagaac accgcggtga ccgagctgcc
    10861 gcacgtcttc gaggaccacg gcctcgaccc ggcggagcgg gcgggcgtcg cggcctacgt
    10921 gaaggccctc caggactggc agtccggcgg ccacgaatgg cacctgcggt ccagccggta
    10981 catgaacgac aggtcgctcg gcatgtccgc cgcccgcatc ccggccctgg tgaagtcggc
    11041 gcggatcagc ctcccccacg tcccgttcca gagggtgggg ccgacgccgc tgccctcgtt
    11101 cgacatcccc tacgcggccc gcgtgaaccc gcaccgcgag cgcgccggcc gcaacctgct
    11161 cgcctgggcg cgggagatgg gcatgttctc cccccacccc cggacgcccg tcccggtgtg
    11221 gagccccgac cggctcgccg ggatggtgct ggaggtctgc gccgcgtccc tcgacccgga
    11281 cgccgatccg gaggcgctcg acctcgccgt ccagtggctg gcgtgcggca cgttcggcga
    11341 cgacttcttc ccggccgtct tcaaccgcga ccgcgacatg gcgggcgcga aggcgttcaa
    11401 cgcccgcgtc ccccggttca tgccgctgga ctgcggcgcc gcccccgccc cggagaaccc
    11461 gttcgaggcg gggctcgcgg acctgtggcc ccgcaccgcc gggcccatgg acgacaaggg
    11521 ccgccgcgag ttccgggcgg ccgtcgagca catggtcgag agctgggtgt gggaactgaa
    11581 caaccacctc cagtcgcgcg tccccgaccc cgtcgactac atcgagatgc gccggcacac
    11641 gttcggctcc gagctgacga tgagcctggc gcgcatcggg cgcgcggacg agatccctca
    11701 gcacgtcttc gagacccgca ccctgcgcga gatcgacgcc tccgcgatgg acgtcgcgtg
    11761 cctgctcaac gactgcttct cctaccagaa ggagatcgag tacgagggcg agctgaacaa
    11821 cggcgtcctc gccgtcggga acttcttcgg ctgcggccgc gacgaggcgc tgcccatcgt
    11881 cgccgacctc atcgcctcgc gccgccgcca gttcgagcac ctcgccgccg gggagctccc
    11941 cgccctctgc gaccggctcg acctggacga cgccgcgcgg gccgcgctct cctcctacgt
    12001 cgaggaactg cgcgactgga tggccgggat cctcaagtgg caccgcgaga ccgatcgcta
    12061 cgacgagcgc gagcccgtcc tccggcttcc caggcccacc ggcctgggga tgtcggcctt
    12121 ccacctcttt gcgcgcgccg cccgctgagc ggnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12181 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12301 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12361 nnnnnnnnnn nnnnnnnncg cgacgagagg agagggcttg ccatccccat tgcgaaaatc
    12421 cacctcgcag gagtcccacc cgcccgacga ccggcggcgc cgcttcgagg acgtctacgc
    12481 ggccaaccgc gcccggatcc tcgggtacgc gctgcgccgg accagtgacc cgcaggacgc
    12541 cgccgacgtc ctggcggaga cgttcctcac cgcctggcgg cggctcgacg acgtcccgcc
    12601 cggcgaccag gcccggctgt ggctgtacgg ggtggcccgg cgcgtcctgg ccaaccacca
    12661 ccgcggcgag cgccgccggt ccgccctggc cgccgacctc ggctcccggc tgcgcgacgg
    12721 cctggccgtc caggacccgt ccggcgacgg gccgaccggc gtgggcgccg cgttccgcgg
    12781 cctgcccgag tccgaccgcg aactgctggc cctggtcggc tgggagggac tcgaccacgg
    12841 cgagatcgcg accgtcctcg gctgctcccg caacgcggtg cggatccgcc tgcaccgcgc
    12901 ccgccgccgg ttcgcccgcg ccctggccag catggacgcg gacgcccccg ccgcccccgc
    12961 gccggccgcc tccctgcgtg ccgcctccac gcccgccacc tccctgcatg ccgcctccct
    13021 gcctgccaag gggcggcgga tcccgaacgg agaccccaca tgaaccgcga catcgacccg
    13081 ctgatcgggg gcctcgcctc cgtcaccgac cggcaggccg ggaccctgct gcccgaggac
    13141 gccgccaccg ccctcgccga ccgcatcacc gcgaccgcgg tcccctcggc ccccgcgcgc
    13201 gggcggcgct cgccggtcat gctcatcgga ctgccgctgg ccgcggccgg catcgccgcc
    13261 gccgccgtca cggcggtcgt gacgacccgc gacggcggac ccggcagcac cccgggcgtc
    13321 acgccgacga gcccgcgcgt cgtgctggcc gcggcgctga cgttcacccg caagggcggc
    13381 tacatcgacg tgcgcgtgcg cgacccgctg gccgacccga agcgctacca ggaggagttc
    13441 gccgcccacg gcctcaaggt cacgctgtcg atggtgccgg cgtccccgtc catcgtcggc
    13501 acggtcgtcg cgatggagac cagcgagaac accgccgagc gcgacgtcac cacgatcacc
    13561 gccaggggcg ggtgcgagac cggcggcgga ggggacgtct gcccggtcgg cgtccggatc
    13621 cgcaccggct acaagggcac cgcctccatc accttcgggc gggaggcccg cccgggcgag
    13681 cagtacaaca gcagcgcccc cgccacggcc ccgggcgagg tcatgcacgg catgacctac
    13741 cgcaagcacc gcgtcggcga ggtgctggcc gccctgcgaa agcggcacgt cacggtgccc
    13801 gagtaccgcg ccatggaggg caacgtcagc aacgtgctga agcccggcca ggtcccgccc
    13861 acgtggtacg tccacagcgc gaccccctgg gccaagaacc aggtcctcct cttcgtgggc
    13921 ccgcacccca ccgaggacgc cggcggcgcg ccgcccgcgt cggcgcctcc cggagcaccc
    13981 gccgctccga gcgcgacccc gacctcctga gcaccggcgg accgccccga ccggggcggt
    14041 ccgccgctct cagggcccgc tcatatcttt gcgcggcggg agagcgtccg gtcgaggagg
    14101 acggtcggca cgatggccgc cgccagcccg gcgccgatcc aggggacggc ggtgagtccc
    14161 gcgccggcgt tcatggcggc gccggcgagg accggaacga ggctgatgcc gagctggaag
    14221 gccgagacgg tcgcggcccc ggcgagcgtc ggcgcctccg acgcgatggc gaacacccgc
    14281 ccgtagatgg ccgggttcag gacgaatccg gcgactccga gcagcagaac gagcgggacg
    14341 acggccgtcg catgcccgga caggaccgcg agcagcacgg aactggccga tatccccagc
    14401 gcgccggcca tgagcgcgtg agtgggccgc ctgtcggcga tccggccccc cacggacagg
    14461 ccgatgaagg cgccgacgcc gaacagcgcg aggatcgcgg gcacccacac gcctggaatg
    14521 ccggtgacgt ccgtcaggaa cgccgcgagg tagttgaacg agatcatgta ggcggcggtg
    14581 ctcaggacgg tggcggcgta gacgacccac agttgcggcc gcctcatggt gcgcagctcc
    14641 ccccgcacgc tcggcttcgc gtccgcgccg gtcgcgggca ccgcgagcag gctcaggacc
    14701 gcgcccgcgg cggtcaggac gaccacgccc cagaacccgc cccgccaccc ggtgaagtag
    14761 ctgagcagcg cgcccgccgg accaccggcg atcatcgcca ggccgagccc gctgacgacc
    14821 accccggacg cccgcgcggt gcggtcggac gtgacgaggc cgatcgcggt gaccgccgcg
    14881 accgcccagt accccgcata ggccagcccg cacaggaagc ggctggccag cagcaccgcg
    14941 taaccgtcga tcaccaggcc ggccgtcacc gagaccgcga agacgacctg cgtggccacc
    15001 agggtggtgc ggcgcggcag gtgcagcgtc aggatggcga agggcggccc gccgacgacc
    15061 accccgacgg cgaacgccga gatcagcgcc ccggcggagg acaggctgat cccgaggtcg
    15121 tcggcgatct ccggcaggac cccggccagc aggaactccg cgctgcccat cgcgaacagg
    15181 ctgaacgcca gcaggtagac cccgagcggc agcctccccc cggagaccga cacccgcggc
    15241 gaagcggtct cgacgctcac cggcccccac ccccgacgcg tccccgctcg acggcacggc
    15301 cctggtcgac ggcctgatgg acgtcctcgt ccagcaggtc ggcgttgacg gcgatggcgg
    15361 cggcggagcc catgccggcg gcggtgacga cctgggcgcg cgggtccgcc acgttgccca
    15421 ccgcccacac gcccggcacg gtggtgcgcc cggtccggtc ggtgacgacc cggcggtcct
    15481 cgacggcgca gccgagtgcg gtcagcaggg cgtcgtgcgg aaccatgcgc gggaacagga
    15541 acaccacgcg gcgcggcacc atgcgcccgt cggccaactc gacgccgcgc accccgtcgt
    15601 tctccgccac cacgcgcttg atctcgccgt ccacgagacg cacgccgcgg gcggtgagac
    15661 gttcatgctc ctcttcgtcc aactccaggg tgtggacgaa caacaccaca tcgtcggacc
    15721 actgccgcag cagcagcgcc tggtgcaccg cgccgggcga ggtgcccaga acgcccatgg
    15781 gcctgtcgcg gaactcgtac ccgtggcagt acgggcagtg cagcacgtcc cggccccacc
    15841 gctccgccac accggggatg ccgggcaact cgtcgcgcag accggtggcc accaccagcc
    15901 gccgcgctcc cagtaccgcc ccgccgacga ggcgcacggt gaaccccggg tcgacgtgct
    15961 ccacccgagc gtcgatcaac gccgccccgt atccggtgac ctcggcccgg cccacctcca
    16021 gcagcgcggc gggccgcatc ccgtcccgcg acaggaaccc ctgcatgtgc gcggccggtg
    16081 cgttgcgggg ctcgcccgcg tccaccaccg cgacccgccg ccgcgcccgc gccagcacca
    16141 gcgccgcgct cagccccgcg gcccccgcac cgaccaccac gacgtcgtac tccgcatcgc
    16201 tcatcgcgat cacctccgcc gcggacggtg ccctgcccac cggctgaacg acaacctttg
    16261 ttgccatttc cgggacgacc gcagtggaat gggggcatgc ctcacccatc cgccatcgcc
    16321 gacgcgctcg ccgaagtcgg cccgcgcctc aagcggctgc gcaacgagcg caacgtgaca
    16381 ctggccgagc tctccgaggc caccgggatc tccaagagca cgctgtcgcg cctggagtcc
    16441 ggtcagcgcc gtcccagcct ggaactcctg ctgcccatct cgcacgccca tcaggtcccg
    16501 ctggacgaac tggtgggagc ccccgaggtc ggcgaccccc gcgtccggct gaccccccgg
    16561 cgcgtgaacg gcaacaccgt cctccccctg acgcgccagc ccggcccgat ccagtcgtac
    16621 aagatggttc tcccggcggc ccggcgcgta cccgacctct gcacccacga gggctacgag
    16681 tggctctacg tgctgtcggg acgactgcgc ctggtcctgg ccgaccacga cctggtgctg
    16741 ggcccgggcg aggtggccga gttcgacacc cggctaccgc actggttcgg caccaccgga
    16801 gaaggcccgg tcgaggtcct cagcctcttc ggccgtcagg gagaacgcct ccacatccgc
    16861 gccaggcccc gcccccgcca ggagcccgcg tcctgacccg tccggcgaag ggcgcgcctg
    16921 ttccgccgag gactccaggc cgcggtccgg tcttcgtcga cgaccgcgtg cgagaccgtc
    16981 gcagccggcg cggtggtcag gaggccagtg cttcgcggac ggtcatcagg gcgaagccca
    17041 agaggttctc gccctgccag gaggcggggt gttcggtgcg ggggtcgtcg gcggtcaggc
    17101 cgatgcccca gacgcggtcc aggggactcg cttcgacgag gatgcggtcg cgggtgccgg
    17161 caaggtagtc gcgaagatct ttgttctggg cgaacttggc ctcgccgccc ttcgtgacaa
    17221 tggtcacacg attgtcgcgc catgtccgct cgtcgaagtc gcggacgcgg cggccgaggt
    17281 ctttcgcacg gcggggatgg gacgcggcga cgatggcggc ggccgtttcc tcgtcgccga
    17341 agaggcgggc cttttccgcc atcatgtagt gctcggcggt cgcgtaggtg acgccgccga
    17401 cggtgaaggg ggacggccac cactggctga ggtagccgcg acctggggtc tggtggcccc
    17461 agaagaacag gaacctcagg cgcgtgccct gctcctggag gcgggtcaac tcggcgacgt
    17521 ccatgggtga gagggtgcca gggccggccg ccgcggtcca tccggtttcc caccgggaat
    17581 ggatgatcga ttggcgttgt tgacaggttt gccgcgaccc ggggtgggga tcgcggtcta
    17641 gaccattttg cggacccggc atctcgccgg gaccatctat tgatccggcc cggccttgaa
    17701 caggaggact gcggtaacaa tggacaacgc cctggcgaac ccccggcgca ccaagatcga
    17761 cgcgtggccc gaatggcggc ccgcggaacc ggactccgag cgtcccgcgg aggccgacgt
    17821 gtccgaggac gagctcgccg cgcattgacg gccttccggc cgatagatga gaacccgccc
    17881 ggctcccccg ggcgggttct tcgtgtccgg gcccggcgga cgagcgccgc ggcgtggttc
    17941 agaccgggcg ggtgagcaag gcgtcgacca cgcggcgggc cttgccggcc gcgtcctgat
    18001 cgcccaggcg cagggcggtg ttggcggcgt tgaggaccgc gtcggtctgg aaggcggcca
    18061 ggtcggggtc caggggggcg atctcaccgg cgtcgaccgc gtgccgcagc tcccccgcga
    18121 tcagggagag ccatcggcgg tgctgctgcg ccagcgtgtc ccggacgggg ccggggcggc
    18181 tgtcgaagtc ggggaggttg gccgcccaga agcagccgcc ggtgaacagc ggcttctccg
    18241 cgtactcgat ccagtacccg accagggccc gtagccgggc ggcaccggcg ggtgcggcct
    18301 gcgcgggacg cacgaccgcg tcggcgaaga gttcgcgggc cgccccgacg gtggccagtt
    18361 gcaggttctg cctggtcctg aacagcgtct ggatgccgct cttgctcacc cgcaggtcgg
    18421 tggccagtcg gccgaagctc agcccgttga gtccctccag cgacgcgacg tccacggcgt
    18481 gccgggtgat cgttcgtcgt gcccgggcgc cgcgcaggag ccgcccgtcg gtcgactcgg
    18541 gctccgggga cgggtcgttc tcgctcatct cctccatcct ggcacagcga ttgcctatac
    18601 gtacgatcga ccgtattgtt tgttcggcca tcggcacacc gacggaggtc cgaccatgga
    18661 cggcgaccgc atgttcgaac tggctcaggc gctggccgcc gccaagagcc gccaggacgt
    18721 ccccgcggcg atgaagctgc tgcaccccga gatggtgctg gagagcccgg ccttcgggac
    18781 gacggcccgc ggcccggccg agaacgagaa ggcgctccgc cggttcttcg cctcgttccc
    18841 cgactacgac gtcgtcctgc agggccacgc cgcgagcggc gaggcgctgg cctgctgggg
    18901 gaccgtccgc atgaccatga ccggcgaccg gttcggcgcc gagccgaacg gcaggcgcgc
    18961 cgaactcccg gtgttcatcc ggttcggttt cgaggacgac ctgatcgccg ccgagtactt
    19021 cttcttcgac ctgtcggagc tgtgcgccca gtcgggggtc tcgaccgacg ccgtccgccg
    19081 cacgctcttc ggctccgcag gctgaggccc tccgacgaga aaggcggcga cccatgccgg
    19141 cagatccccg tgtgagggac gtcgacggga tccggaccga gttcctcttc gacatcgtcg
    19201 tcgatctgga cccgcccctg gacttcggcc gggggccggt cgggcggcgc gtcctgttcg
    19261 gctccgccgg cgggacgttc gagggaccgg cgctgcgcgg cgaggtcctg ccgggcggcg
    19321 gcgactgggc gctgttccgg tccgacggga ccatgctcct ggacgtccgg ctcaccctgc
    19381 gcaccgacga cggcgccctg ctgcacatga cctacggcgg ccgctacacc accccgccgg
    19441 gcctgcgcgc cgagatggcc gaccccgccg ccaggcaccg ggtcgacccg tcccggtact
    19501 acttccggac caatccgctg ttcgagacgg gagccgagca gtacacctgg ctcaacgacg
    19561 tcgtctgcgt gggatcgggc tacctcgtcc aggacgggat cgcctacaag gtcttccagg
    19621 tgctgtgaag atcctccgga cgccgagcgg tcagaggacg tccaccgcga ggtcgcggac
    19681 ggttcgctcg tccacctcga cgccgaggcc gggggcgtcg gggacgcggg cggtgccgtc
    19741 gcggatctcg accgtcggcc ccgcgtacgg ggagtcgatg aactggcggc cgttgaggtc
    19801 gaccggggtg tcgatgccga aggccgagaa gaggtgcagg gacgcggcga ggccgaggtc
    19861 ggagtcggtg aggccggagc ccatcagcgc gacgccgcag tcctcggcga gggcgcacag
    19921 gcggcgggac agggtcaggc cgccggtgcg ctggaccttc gcgatggcga cgtcgaccgc
    19981 gtcgaggcgg acgaaggtcg ccaggtcgga tgggtggcgc aggctctcgt cgagggcgac
    20041 cgggatcggg catgcgtcgc ggaggcggcg caggcccacg atgtcgttgg cggggagggg
    20101 ctgctcgaac gcggtcacgc cgaggtcctc caggcggcgc gccagcgcga gggccgagcg
    20161 gacggtgtag ccctggttcg cgtccaccca gagcgccgcg gcgtcacccg cgtggagccg
    20221 gacggcctcc acgacgtcgg cgtcctcggg gcccaggccg accttgacct tgaaggcgcg
    20281 gtaccccagg ccgcggccct cggcgacgct gtcggccacc tcggcggagg atcggccgga
    20341 gacgatccac ccgagatcga tcgtctcccg tcggcgccgg ccccacatga cgcccagcgg
    20401 gacgccggcg gcgcggccga ggaggtcgtg gagggcgacg tccacggcgg acttggccag
    20461 cggcgcgccg atgctgaagc cccggttgac ggcccggtcg aaggcggtcg tcacgccgtc
    20521 gaggtcccag gcgggacggc cggtgatcgc cggcgcgagg taccggtcga tggtggtgac
    20581 gatggactcg gcggtctcgt acgtccaggc ggggatgggg gtcgcctcgc cccagccgtg
    20641 cgcgccctcg gcgctgacct tgaccaggac gcgcaggctg ggccgtccgg cgacggcgac
    20701 cgcgccgccg gacaccccga acgagcgccg ggtgggcagc gcgacgcaga acgtctcgat
    20761 tttttcgatc ttcattcacg cctccgggaa gcgggcgccc gcggctcagc cgggcggtgc
    20821 ggtgctggcg cgcagcacca cctcgcccgc gacgcgctcg atgcggctgc ggcgggtggc
    20881 gggctcgcgc agggccagtc ccatgacgcg ctcccccatc gcgttcagcg gcagcgcgac
    20941 ggtggtgagc gccggggtca ggtcgcggac gatcgagatg tcgtcgaatc cggcgagcga
    21001 catctccccc ggcactaaca cgccgtggtc gcgcagcgcg gcgagcgcgc cgaccgccat
    21061 cacgtccgtg acggcgaaca cgcaggtcgg acggttttcg cggcggagca gctcggccgc
    21121 cgcccggtag ccgccgtcgc gggtgaaggg ggcttcgacg atgtgctcgg gcgcgacgcg
    21181 gacgcccgcg tcggcgagcg cctcggtgaa cccgccgagc cggtcgtgga cggtcgtcag
    21241 ggcgcgcggg ccagtcagca cgccgaagcg gcggtggccg aggtcgagca gggcgcgggc
    21301 gagggcggcg gcgccctccc ggttctgcgg caggatggcg tcgaccttga ggctgcggtg
    21361 ccggctgagg acggcgacgc gaccgccggt gcgctggtag gggtcgagct cggcggccat
    21421 cgcccgctcc cactcgcggt cctcgaagcc ggagccgatg agcaggatcg cgcgggcacg
    21481 ctgggcgcgc agcatcgcca cgtactcgac ctcgcgcgcc gggtcgcgga acgtgctggc
    21541 gagcatcacc agcatcccgt actcggcggc ggtgcgcatg acgccgcggg ccacggcggc
    21601 gaagtagggg tcgctgacgt cgtggcagac caccccgacg gacttgctgg aggagctggc
    21661 gagcgcctgg gcgtgcgcgt tcggggtgta gctcagctcg gccgccgcgg ccaggacgcg
    21721 ttcccgcagg tcggcgcgga cctgcgaggt cccgttcagg acgcgggacg cggtggcgag
    21781 cgagacgccg gcatcccgcg cgacgtcctg cagggtcacg tacgctcggt cgccggtgcg
    21841 ctccccctcg gccgcttccg tcatccccgc ccccctcggc cggcacgggc cctcgcggcg
    21901 ggttcctgac gaagaccctc ttgaccgcgg tgcgtgccgg ttcttacggt acatcagaaa
    21961 gcgctttctg aacgcgcttt ccgaaccacc ccgtccggag gaacccatgg tgagtcaggg
    22021 tacgacggcc gcaccgccct cggcggacgc ggcgggcgtc gtggaacgcg ccaggcccgg
    22081 cgcgggcgaa cggatccgcg acggcctgga acggtcgtgg cggccggtcg ccctgctggt
    22141 ggcctgct
//
