LOCUS       NZ_BMRD01000001        21053 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Actinomadura citrea strain JCM 3295 sequence01, whole genome shotgun
            sequence.
ACCESSION   NZ_BMRD01000001
VERSION     NZ_BMRD01000001.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Actinomadura citrea
  ORGANISM  Actinomadura citrea
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 994668)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: BGI assembly pipeline
            Genome Coverage                   :: 127X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014648455.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 03:26:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,339
            CDSs (total)                      :: 8,265
            Genes (coding)                    :: 8,175
            CDSs (with protein)               :: 8,175
            Genes (RNA)                       :: 74
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 90
            CDSs (without protein)            :: 90
            Pseudo Genes (ambiguous residues) :: 0 of 90
            Pseudo Genes (frameshifted)       :: 12 of 90
            Pseudo Genes (incomplete)         :: 83 of 90
            Pseudo Genes (internal stop)      :: 3 of 90
            Pseudo Genes (multiple problems)  :: 8 of 90
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:33:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 662830
            Orig. end                         :: 683883
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMRD01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21053
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="3"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21053
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21053
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11053](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11053)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    454..468
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 24.85"
                     /tool="antismash"
     gene            complement(971..1774)
                     /locus_tag="IEZ14_RS03150"
                     /old_locus_tag="GCM10010177_06390"
     CDS             complement(971..1774)
                     /EC_number="2.8.1.10"
                     /GO_function="GO:1990107 - thiazole synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017591120.1"
                     /locus_tag="IEZ14_RS03150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_06390"
                     /product="thiazole synthase"
                     /protein_id="WP_179833779.1"
                     /transl_table=11
                     /translation="MDTGKAGPAEAGTDGLVIAGEELGSRLIMGTGGAPSMAVLREALT
                     ASGTALTTVAMRRVAPSARGSVLDVLTECGIRVLPNTAGCFTAGEAVLTAKLAREALGT
                     NWVKLEVIADERTLLPDPIELVEAAEQLVDDGFVVLPYTSDDPVLAHRLEQIGCAAVMP
                     LGSPIGSGLGIRNPHNIELIVERATVPVILDAGLGTASDAALAMELGCDAVLLATAVTR
                     AQSPARMAAAMRHAVEGGRLARLAGRIPKRRYAQASSPFDGLATS"
     gene            complement(1777..1977)
                     /gene="thiS"
                     /locus_tag="IEZ14_RS03155"
                     /old_locus_tag="GCM10010177_06400"
     CDS             complement(1777..1977)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853360.1"
                     /locus_tag="IEZ14_RS03155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_06400"
                     /product="sulfur carrier protein ThiS"
                     /protein_id="WP_179833780.1"
                     /transl_table=11
                     /translation="MKVIVNGEARELPDGASVAEVVASVTAVATGVAAALNDEVVRRAE
                     WEATPLRDADRIEVLTAVQGG"
     gene            complement(1974..3101)
                     /gene="thiO"
                     /locus_tag="IEZ14_RS03160"
                     /old_locus_tag="GCM10010177_06410"
     CDS             complement(1974..3101)
                     /EC_number="1.4.3.19"
                     /GO_function="GO:0016647 - oxidoreductase activity, acting
                     on the CH-NH group of donors, oxygen as acceptor [Evidence
                     IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene="thiO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011291491.1"
                     /locus_tag="IEZ14_RS03160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_06410"
                     /product="glycine oxidase ThiO"
                     /protein_id="WP_179833781.1"
                     /sec_met_domain="DAO (E-value: 3.1e-73, bitscore: 243.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQIVIIGAGVIGLATAWRTAAGGAAVTLVDPAPASGASSVAAGML
                     TPVSELTYGEEPLLRLGLASRDRYGAFVAELEELTGLETGYRTDGILEVAFDSDDLRHL
                     DDLRRFQEDLGIPAEALTGRECRRLEPMLAPGVRGGLLAPEDGSVDPRRLAPALLAACE
                     RLGVRLVRRRAERVVVENGAAAGVGLDDGTVIPADRVLLAAGPWSGDLGGLPPGTVPPV
                     RPVKGQVIRLRTRAPFLRRATRGLVRGSSVYLVPRADGEIVLGATQEELGFDTRVTAGG
                     LWELLRDARELLPGITELEFAEVRAGLRPGSPDNAPVMGPTALPGLLVGTGHFRNGILL
                     TPVSADILSAMLLDGPVPEVAGPFAPDRFSPEVSA"
     regulatory      complement(3091..3204)
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(3121..3134)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
     gene            3297..4532
                     /locus_tag="IEZ14_RS03165"
                     /old_locus_tag="GCM10010177_06420"
     CDS             3297..4532
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889487.1"
                     /locus_tag="IEZ14_RS03165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_06420"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_179833782.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3.1e-46, bitscore:
                     153.7, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERVIVVGGGLAGVRAVEALRSKGYEGALTLVSAERHRPYDRPPL
                     SKAVLAGESDDTTVDADWDALRCELLLGERATGLRLDEPGRGGTVESTAGDLPFDGLVI
                     ATGAAPITLPGEGRQHVLRTIDEARDLRARLTAGARIVIVGAGWIGAEVATTAARRGCA
                     VTVVEAADTPLAGAIGPEVGALTAPWYAEAGVELRTGVKVAEVRDGGLALAGGGRVDAD
                     EVVVGVGVRPVLSWLEGSGLLLERGVVTDGSFRTYMGEEDTGALRPDVVAVGDCAAWWS
                     HRYGRRLLVEHWDTALNAPEVAAAALLGRDAVYDAAPYFWSEQFGRMVQYAGDHSASER
                     LVRRGDPSDPRWAVAWLTGDRLDAILTVGRPRDLVQARRVIAAGTPVDPEAIADPDVPV
                     RQAVRAERSAGT"
     gene            4591..4965
                     /locus_tag="IEZ14_RS03170"
                     /old_locus_tag="GCM10010177_06430"
     CDS             4591..4965
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853357.1"
                     /locus_tag="IEZ14_RS03170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_06430"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_179833783.1"
                     /transl_table=11
                     /translation="MHATVDSALDPRTDALAGEWLTLGETAERLGIRPNRIKQLIHEHR
                     ILAVRRGGEPMVPAAFIKDGQVIKGLPGTLTLLSDAGFDDAETIRWLFTADDTLPGTPV
                     DALTENRGTEVRRRAQALAF"
     misc_feature    complement(5053..5067)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.06"
                     /tool="antismash"
     gene            5073..5759
                     /gene="thiE"
                     /locus_tag="IEZ14_RS03175"
                     /old_locus_tag="GCM10010177_06440"
     CDS             5073..5759
                     /EC_number="2.5.1.3"
                     /GO_function="GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1280: thiamine-phosphate pyrophosphorylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853356.1"
                     /locus_tag="IEZ14_RS03175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_06440"
                     /product="thiamine phosphate synthase"
                     /protein_id="WP_179833784.1"
                     /transl_table=11
                     /translation="MSRHLPTERAVALRARLSRARLYLCTDARERQGDLPAFLDAVLAG
                     GVDLVQLRQKGLEARQETAYLEVFRAACERHGALLAVNDRADIAHAVGADVLHLGQDDL
                     PVPAAREIVGGDMLIGRSTHSGEQASAAAAEPGADYFCAGPVWPTPTKPGRPAPGPKLL
                     EYVAAQRVARPWFAIGGIDLGNLDEVLAAGAERVVVVRAITEADDPGAAAARFARRLAA
                     RPLGTG"
     misc_feature    5768..5783
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.04"
                     /tool="antismash"
     misc_feature    5769..5782
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.16"
                     /tool="antismash"
     misc_feature    5810..5825
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.05"
                     /tool="antismash"
     gene            5820..5978
                     /locus_tag="IEZ14_RS03180"
                     /old_locus_tag="GCM10010177_06450"
     CDS             5820..5978
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853355.1"
                     /locus_tag="IEZ14_RS03180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_06450"
                     /product="hypothetical protein"
                     /protein_id="WP_179278861.1"
                     /transl_table=11
                     /translation="MSVGPDDDRTVDLDDDLDVLPDQTSDDTDAGWGEWRTGDDDARLL
                     EDRPPHW"
     gene            complement(5992..7080)
                     /locus_tag="IEZ14_RS03185"
                     /old_locus_tag="GCM10010177_06460"
     CDS             complement(5992..7080)
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630835.1"
                     /locus_tag="IEZ14_RS03185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_06460"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_229809900.1"
                     /sec_met_domain="Pkinase (E-value: 9.7e-45, bitscore:
                     148.8, seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 8.9e-07, bitscore: 24.9,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPHDTSRGRTDPHPPRSSSPRPGRAARAGQPHGAHAGRPAKAHPG
                     PGRVPARPAHGRDHRAGAPLGPDDPCGLGVYTLLGRLGEGGQGVVYLGRDGDGGLVTVK
                     LLRGGVAAGQRARSRFAKEADAALRVSGRHTARVLDADMTGDRPYIVSEFVEGPSLQHV
                     VADRGPLSPPRLRKLALRTAAALAAIHRAGIVHRDFKPGNVLLGPDGAKVIDFGIARTA
                     DATPLTTGPVGTPAYMAPEQIEDEPVGPPADVFAWGAAMVFAATGRPPFGTGPSAAVMR
                     RVTSRKPDLGDMQGPLRELAARCLDKNPAARPTASQIVRALREGQAPAPKPRPTRIPRY
                     RWRMMVALGAVVAAGFLLGVLT"
     gene            complement(7173..9326)
                     /locus_tag="IEZ14_RS03190"
                     /old_locus_tag="GCM10010177_06470"
     CDS             complement(7173..9326)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630834.1"
                     /locus_tag="IEZ14_RS03190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_06470"
                     /product="beta-glucosidase"
                     /protein_id="WP_179833785.1"
                     /transl_table=11
                     /translation="MRPGRGLPAALAVASALALTAVVTAASAPGEARAAAGRCGDLARR
                     PWCDAALAPDRRAALLLPRMTDDEKISMLASDDPLGGPLGGFSENAHADTADGIDRLGI
                     PPVRMADGPAGVRQGTATALPAPIALAAAFDPEAARLYGGTVAWEARHRGNDLVFGPTV
                     DVLRTPRNGRTFEGFGEDPYLSATLGVPWIRGAQAQGVMTSVKHMAVYTQETDRLSLGM
                     NVDPRTLREIYLPPFEAAVKDAGTATVMCGFGKLNGRWACQDDAVLNGILRSEWGFTGF
                     VPSDHTAVQDAAGAANGGLDMELPFGMKYNAFLLKLAVAQKKVTQAAIDAHVRAVLRTM
                     FRFGVFDRQAYPNDLGRADRTASRNAARVVEEGGITLLKNDGVLPLRAPGSIALIGRAA
                     RQSPSGFGSAKVVPFATVSAQDGISRRAGSGTRVTYHDGDDRGGAAATARAADLAIVFA
                     TDSQGEFFDKSCLTLRCGEPLRGDQDGLISEVAKANPNTVVVLNTGGPVLTPWAGQVRG
                     IVEAWYPGQEAGDALARVLYGDVDPGGRLPVTFPANENDAPASGNPAQYPGLDKNTTFS
                     EGVMVGYRHYNAKGIAPRFPFGHGLSYTTFAYSGLVATSKSVQVTVTNTGRRAGVAVPQ
                     LYIGMPSPGAEVPQPPKQLKGYAKVALAPGRSAKVTFPLSSRSFAYWNEVAKAWKVAAG
                     CYKIMVGESSRRIVGSAALGACR"
     gene            complement(9323..9907)
                     /locus_tag="IEZ14_RS03195"
                     /old_locus_tag="GCM10010177_06480"
     CDS             complement(9323..9907)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1298: putative carboxymuconolactone decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018658562.1"
                     /locus_tag="IEZ14_RS03195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_06480"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_179833786.1"
                     /transl_table=11
                     /translation="MCADTPGDRVPRFDPLPEEEWDDVVRAVTETIGPLNVITTLARHP
                     ELFRSWIGFGSMLLMNGTLGARDRELAILRTAHHRSCAYEWDHHRRVALDAGLTEDEIA
                     ALREDPDGHGWSDDDRMVLAAADELHESGTVSDATWTELATRFGEHELIELVMLIGHYH
                     MVAFTLNALRVQNEDDGRHEDQVPREEGAGG"
     gene            complement(10001..11053)
                     /locus_tag="IEZ14_RS03200"
                     /old_locus_tag="GCM10010177_06490"
     CDS             complement(10001..11053)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853353.1"
                     /locus_tag="IEZ14_RS03200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_06490"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_179833787.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1e-48, bitscore:
                     161.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTTRIRKEVDEALLAFVDLRRPALRAISEDLAPLLSALDALLGG
                     GKRLRPAFCYWGWRAAGGEDGPGIVAAAASLELLQASALIHDDVMDSSDTRRGQPSAHR
                     RFEALHRAQAWPGDAESFGGGAAILLGDLCLAWSGEMFETSGLDGASRLRGRAVYDLMR
                     TEVMCGQYLDMLEGARRQANVATALRVVEYKSAKYTIERPLHLGAALAGARPDVAAALT
                     GYGLPLGIAFQLRDDVLGVFGDPAETGKPAGDDLREGKRTVLVALTLERASAAQAAALE
                     RRLGDPALDRPGVDELRAIIEETGGLAACEAMIERYLREAEKALRAAPVTAGAREALAE
                     LAVAATTRST"
     misc_feature    complement(11114..11128)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.03"
                     /tool="antismash"
     gene            11253..12188
                     /gene="metF"
                     /locus_tag="IEZ14_RS03205"
                     /old_locus_tag="GCM10010177_06500"
     CDS             11253..12188
                     /EC_number="1.5.1.20"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630831.1"
                     /locus_tag="IEZ14_RS03205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_06500"
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="WP_179833788.1"
                     /transl_table=11
                     /translation="MRRVRPDRPPTVRELLASGERSFSFEFFPPKTDKGARNLWRTIRE
                     LESLHPTFVSVTYGAGGGTRDTTVDIVERIATDTTLTPVAHFTAVNHSQAELRNLIGRF
                     AAVGVRNVLALRGDPPGDPMGEWVKHPDGVEYAAELVRMIRSYGDFSVGVAAFPYKHPR
                     SRDIESDTRHFVAKCRAGADYAITQMFFRAEDYFRLRDRVDAAGCDVPILPGIMPVTRL
                     STIERSEQLSGAPFPPEVRARFEAVADDPEAVRRLGIEHAAELCCELLDQGAPGIHFIT
                     FNQSTATREVYSLLDGAGYGARGSVPPITA"
     gene            complement(12125..12727)
                     /locus_tag="IEZ14_RS03210"
                     /old_locus_tag="GCM10010177_06510"
     CDS             complement(12125..12727)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018658565.1"
                     /locus_tag="IEZ14_RS03210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_06510"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_229809901.1"
                     /transl_table=11
                     /translation="MRDPKLREIDERAFLRRLSPMLDVYAAAMEPPNEQLPGRHTIMER
                     HASYPGFRACVVERRGALPVMPAPVQGFAYGFHGARGQWWHDVVHQALSDREGPEHADS
                     WLENAFEVAELHVHPQAQGRGLGRALLTALCNGRPERTVVLSTLDRRPDTPARTLYRSV
                     GMVDLLTDFEFPGGGPRYAVMGGTLPLAPYPAPSSSE"
     gene            complement(12738..13070)
                     /locus_tag="IEZ14_RS03215"
                     /old_locus_tag="GCM10010177_06520"
     CDS             complement(12738..13070)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630829.1"
                     /locus_tag="IEZ14_RS03215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_06520"
                     /product="hypothetical protein"
                     /protein_id="WP_179833789.1"
                     /transl_table=11
                     /translation="MAAPPPPGSLPPPITGAASARLSPAEQPNPEYQQLYQAYADAYGS
                     IDRLRQALDGPVKALGGTDAWLGPEAREWGGQLDANRGTLRKAADRILWDLYDRLSVTQ
                     RTVTRV"
     gene            complement(13080..13943)
                     /locus_tag="IEZ14_RS03220"
                     /old_locus_tag="GCM10010177_06530"
     CDS             complement(13080..13943)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEZ14_RS03220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010177_06530"
                     /product="hypothetical protein"
                     /protein_id="WP_179833790.1"
                     /transl_table=11
                     /translation="MASTGGVMATQMRTGPAARDPEFRGIDPPALNQVIRQLQDAQNAI
                     QGWLNGHRPPPGVSTAGYRQADEVARWAAEQLGMLTRRYNFAVTHPSPGGGIDMPPAPT
                     PAPVPRKTGGGPVGTPRPVKAPPHRTSPAKAAPRPTPHGAGDLGGFPDRPAAARAAKAD
                     ALSVAASVQHGRPVPDPVWRHLEANAGDPDYTEKLYERLGPAGAADLLKAAQGDKARLE
                     AVQQSLGTSSHHLTMDVRWLRAFLAGADHAGVRPVAVQVLLGADMSGRTREAIARLDLH
                     PSTATA"
     misc_feature    complement(13934..13949)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.74"
                     /tool="antismash"
     gene            complement(13978..14328)
                     /locus_tag="IEZ14_RS03225"
                     /old_locus_tag="GCM10010177_06540"
     CDS             complement(13978..14328)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018658568.1"
                     /locus_tag="IEZ14_RS03225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_06540"
                     /product="arsenate reductase family protein"
                     /protein_id="WP_179833791.1"
                     /transl_table=11
                     /translation="MELWHNPRCSKSRAAKAALDEAGVRYTERRYLDEPPTAQELDDVL
                     TRIGAEPWDVARLNEPVAKELGLRDLERDRARWIEVMVANPVLIQRPIVVADETAVVAR
                     DAESVGRALDSQ"
     gene            complement(14328..14792)
                     /locus_tag="IEZ14_RS03230"
                     /old_locus_tag="GCM10010177_06550"
     CDS             complement(14328..14792)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889494.1"
                     /locus_tag="IEZ14_RS03230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_06550"
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_179833792.1"
                     /transl_table=11
                     /translation="MHPNAEIVAKALLDLGAAGAIVELPDSARTAQAAAEQLGCEVGAI
                     ANSLVFDADGSPLLVMTSGAHRVDTVKVAALVGAAKVRRASPEFVREATGQPIGGVAPV
                     GHPEPIRTLVDIWLERYDEVWAAGGHPHTVFPTSYGELLRITGGAPAEVE"
     gene            14816..15604
                     /locus_tag="IEZ14_RS03235"
                     /old_locus_tag="GCM10010177_06560"
     CDS             14816..15604
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541679.1"
                     /locus_tag="IEZ14_RS03235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_06560"
                     /product="peptidoglycan-binding protein"
                     /protein_id="WP_179833793.1"
                     /transl_table=11
                     /translation="MRGRAIDVRKSAVLLIGAVVLTGCNDIDAAGSAPSKEAPKGTPSK
                     APATPTPSPGHRKLKPGAKGPDVQALQRRLKALHYDPGKADGKYGPSTQTAVWAFQAVN
                     RLKQKSTLSASFWKALDAPKEPRPVAEKREKNRVDVDLKRQYLVLYKSGSPRLITHVSS
                     GSGEYYCAKDRGATVARCRYATTGTGDFRTGRRASGWETSPLGQLYNPIYFNGGIAFHG
                     ALDVPMHPASHGCVRMPMHIARYFPDEVGTGVPVHVRRPR"
     misc_feature    complement(15658..15673)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.69"
                     /tool="antismash"
     misc_feature    15718..15733
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 25.93"
                     /tool="antismash"
     misc_feature    complement(15719..15732)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: strong, score: 24.0"
                     /tool="antismash"
     gene            15866..16369
                     /locus_tag="IEZ14_RS03240"
                     /old_locus_tag="GCM10010177_06570"
     CDS             15866..16369
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853345.1"
                     /locus_tag="IEZ14_RS03240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_06570"
                     /product="SAV_6107 family HEPN domain-containing protein"
                     /protein_id="WP_089312401.1"
                     /transl_table=11
                     /translation="MSGTMTARGVHSAAQSVPSPSPRPRHRPMPAPRPAHTAVGQLHAA
                     RMGLAEAAEATSPAVRYVCAHLAALRAAAAVLASKEPLETHRRGRPRSVWVLLPEAEPA
                     LREWAAFFAAGADKRAAAEAGLPRAVTPRDAEELLHDAEVFVTLVEDTLGVDGQPTLPV
                     PEAG"
     gene            16568..17755
                     /locus_tag="IEZ14_RS03245"
                     /old_locus_tag="GCM10010177_06580"
     CDS             16568..17755
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1189: L-carnitine dehydratase/bile acid-inducible"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013132337.1"
                     /locus_tag="IEZ14_RS03245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_06580"
                     /product="CoA transferase"
                     /protein_id="WP_179833794.1"
                     /transl_table=11
                     /translation="MTDLLPLDGMRVVELSSFVATPLGGMTLAQLGADVIRVDQIGGGP
                     DIDRWPLAPSGRSLYWAGLNKGKRSVALDLRSPEGRELVAALVTEGGVVLTNAPPRPGL
                     SYEELKAARPDLIHVRLQGTREGGNAVDYTVNATMGFPSITGPADLEAPVNHALPAWDV
                     ACGLYMAVGLLAAERHRSRTGEGRRIQVALQDVALATAGNLGYLAEAQLGEPRARLGNH
                     LFGDFGRDFATSDGRVMVAILTARHWRDLVEATGLGEVVEALGRALGADFRRAGDRYAH
                     REALGGVLASWFARRTCEQVADGLRRTSVLWSRYRDFAEVAAGLRDEPLMAPLDQPGVG
                     PHLAPGSPVRLGETSPPPVPAPTLGEHTDEVLRDVLALPAERVEALRGNGTIIGW"
     gene            complement(17742..18296)
                     /locus_tag="IEZ14_RS03250"
                     /old_locus_tag="GCM10010177_06590"
     CDS             complement(17742..18296)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018654327.1"
                     /locus_tag="IEZ14_RS03250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_06590"
                     /product="hypothetical protein"
                     /protein_id="WP_179833795.1"
                     /transl_table=11
                     /translation="MTVLSRPAHAARPAVRPAPRWAHLAAHTITLLALPSGIWRLGLAL
                     GLHLGYTEEGYRTVCPPGFWGPGYLVLLAVLSEGAALSALGLVQRWGEVVPRWIPVIGG
                     RTIAPSAVLIPAWAGVAVLAVLWTPLAAWWSMPGDDMTPAGHTVVGFLYLPLVAWAPLL
                     AALAVAYRRRRRREPARVTSQ"
     gene            18427..19851
                     /locus_tag="IEZ14_RS03255"
                     /old_locus_tag="GCM10010177_06600"
     CDS             18427..19851
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853344.1"
                     /locus_tag="IEZ14_RS03255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_06600"
                     /product="MFS transporter"
                     /protein_id="WP_229809902.1"
                     /transl_table=11
                     /translation="MAGRGGRGLVPLLAFLGVMAYSLSMAVVTPALPQIQHGLHTTPAG
                     AAWALTAMTLSAAVATPVVGRLGDLYGARRVLLCVLAVATAGTVVAALAATVPVMLAGR
                     VLGGVGGGVFPLAYTIIRDVLPPARRAPAVGLMSSMLGLGGAVSWCLAGPIIDLLGWRW
                     LLWLPVIGLVPGVVLAWWIVPAGRRDGSSRAAARVDWWGAVLFAAWLVAALTALTEGMD
                     WGWTSPGVLGLLALALAGAGAWLWVEGRVSEPLIDLRLMRVRGVWTANAASLLSGYALM
                     AGGLLFPLLVQLPEDTGYGFGGTATQAALLQLPASVGMTVAGMTAGLLDRRVGSRTVLL
                     GGAVMTGLGYAFVAFEHGAMWHLYVGGLARGVGLGFAYAAVATLVVAAVPPEETGVATG
                     INTLLRTVGASLGTQVSAVIVVAVPGEGGFSAGFAVSAAVTAAVLPLALLVPRPGRRRE
                     HGTGPGAVPDPVTVVR"
     gene            complement(19882..20376)
                     /locus_tag="IEZ14_RS03260"
                     /old_locus_tag="GCM10010177_06610"
     CDS             complement(19882..20376)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017622275.1"
                     /locus_tag="IEZ14_RS03260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010177_06610"
                     /product="transcriptional regulator"
                     /protein_id="WP_021597992.1"
                     /transl_table=11
                     /translation="MPSEYAKALGARLRAIRTQQGLSLHGVEEKSRGRWKAVVVGSYER
                     GDRAVTVQKLAELADFYGVPVSELLPGGAAPSPLGPTPKLVIDLERLQQLPKDKAGPLA
                     RYAATIQSQRGDYNGKVLSIRQEDLRSLAVIYDKSPTELTEELIGWGVLDPEARRAVES
                     F"
     misc_feature    complement(20357..20371)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 20.64"
                     /tool="antismash"
     misc_feature    20495..20511
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.64"
                     /tool="antismash"
     misc_feature    complement(20527..20540)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.29"
                     /tool="antismash"
     misc_feature    complement(20528..20541)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.59"
                     /tool="antismash"
     misc_feature    complement(20652..20667)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     misc_feature    complement(20959..20973)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
ORIGIN
        1 cgccgccgag ggtgaccagc ccggggacct cgtcgaggaa cagccacgac atccccacca
       61 cgagggcggg cgcggcgtag gtggtggcgc ccatcttccc ggcggtcgtg cgggccaggg
      121 cgtatcccca ggtcgtgaag gcgaccgcgg tcgggaagac gcccagatag accatgttga
      181 gggtggcgcc cgcggaggcg tccgcggcct gcgagacgag ctgcccggag aacggcaggc
      241 aggcgacagc gccgatcgcg caggagaacg tggtgaactg cagcgccgac gcgtgcctca
      301 aggccggctt ctgggcgacg acgcccgccg cgtaggtgac ggcggcggcc aggcagagca
      361 gcaccccgcc gacggacgaa cggccgtcgc ccgacatcga cagtccgacg acggcggcgc
      421 cggcgaacga cacggccatg ccgagcatca gccgggacga caggccctcc ttcagcagcc
      481 agccgccgag gagcgcgatg aggatcggcc cgatgttgac gacgagggcg gcggtgcccg
      541 cgtccaccag ttgctcgccc cagttcagca cgaccatgta ggcgccgaac cacaggacgc
      601 cggcggtgac gatgccgggc caggcggcct tgggcggcag gcccccgccc cggacgagcc
      661 agatcgtccc cagcacgacc gtcccggaaa ggaggcggcc gagggcgagg gcgccgggac
      721 tgtactcggc gcccgcgctg cggatggcga cgaaggccga ggcccagaac accaccgtga
      781 ccgtcgccgc cgccaccgcg agcttgccgg cgcgcgcgcc gctgtcctgc tgcatgtcac
      841 gcaccttagg gagaggacgt ttccatcaac accgaagcga tctgtggggt tgcgccccgg
      901 tatgcccagt ctgatggcgc gtgacttttc aggtccagcg aaatcttcta caggtggatc
      961 tttagcatcg ctacgaggtc gcgagtccgt cgaacgggga ggacgcctgg gcgtagcggc
     1021 gcttggggat gcgcccggcg agccgcgcga gccgcccgcc ctcgaccgcg tgccgcatcg
     1081 cggcggccat ccgcgccggg gactgcgcgc gggtgacggc ggtcgcgagg agcacggcgt
     1141 cgcagccgag ctccatggcc agggccgcgt cggacgccgt gccgagcccc gcgtccagga
     1201 tcaccgggac ggtcgcgcgc tcgacgatca gctcgatgtt gtgcgggttg cggatgccga
     1261 ggcccgaccc gatcggggag ccgagcggca tcacggccgc gcagccgatc tgctccagcc
     1321 ggtgcgccag gaccgggtcg tcactggtgt agggcaggac gacgaagccg tcgtcgacga
     1381 gctgctcggc ggcctcgacc agctcgatcg ggtcgggcag cagcgtgcgc tcgtcggcga
     1441 tcacctctag cttgacccag ttcgtcccga gtgcctcccg ggcgagcttg gcggtcagga
     1501 cggcctcgcc cgcggtgaag cagccggcgg tgttcggcag cacccgtatg ccgcactcgg
     1561 tcagcacgtc cagcaccgag ccgcgcgcgg acggggccac cctgcgcatc gcgaccgtgg
     1621 tgagcgccgt cccggacgcg gtcagcgcct cgcgcagcac cgccatgctc ggcgccccgc
     1681 ccgttcccat gatcagccgc gagcccagct cctcgcccgc gatgaccagc ccgtcggtgc
     1741 ccgcttctgc ggggcccgct tttccggtgt ccatcctcaa cctccctgga ccgcggtcag
     1801 cacttcgatg cggtcggcgt cccgcagggg cgtggcctcc cactccgcgc gccggacgac
     1861 ctcgtcgttc agcgccgccg ccacgcccgt cgcgacggcc gtgacggacg cgacgacctc
     1921 ggccacgctc gcgccgtcgg gcagctcgcg cgcctcaccg ttgacgatca ccttcatgcg
     1981 ctcacctcgg gggagaagcg gtcgggggcg aacggcccgg cgacctcggg gacgggcccg
     2041 tccagcagca tcgcggacag gatgtcggcg ctcaccggcg tgagcaggat gccgttgcgg
     2101 aagtgcccgg tgcccacgag cagcccgggc agcgcggtcg ggcccatcac gggcgcgttg
     2161 tcgggggagc cgggccgcag cccggcgcgg acctccgcga actccagctc ggtgatgccg
     2221 ggcagcagct cgcgggcgtc gcgcagcagc tcccacagcc cgccggcggt gacgcgcgtg
     2281 tcgaagccca gctcctcctg cgtggcgccg aggacgatct caccgtccgc acgcggcacc
     2341 aggtagaccg acgacccccg gacgaggccg cgggtcgccc gccgcaggaa cggcgcgcgg
     2401 gtgcgcagcc ggatcacctg gcccttgacc gggcggacgg gtggaacggt cccgggaggc
     2461 aggccgccga ggtcgcccga ccacggcccc gcggccagca gcacccggtc cgcggggatc
     2521 acggtgccgt cgtccaggcc cacgccggcg gcggcaccgt tctcgacgac gacgcgctcg
     2581 gcccgccgcc ggacgagccg gacccccagc cgctcgcacg ccgccagcag cgccggggcg
     2641 aggcggcggg ggtcgaccga gccgtcctcg ggggcgagca ggccgccgcg cacgccgggc
     2701 gcgagcatcg gctccagccg ccggcactcg cggccggtga gcgcctcggc ggggatgccc
     2761 aggtcctcct ggaagcggcg caggtcgtcc aggtgccgca ggtcgtcgga gtcgaaggcg
     2821 acctcgagga tcccgtcggt gcggtagccg gtctccaggc cggtcagctc ctccagttcg
     2881 gcgacgaagg cgccgtaccg gtcgcgggag gcgaggccga gccgcagcag cggctcctcg
     2941 ccgtaggtca gctcgctgac cggggtgagc atgcccgccg ccacggagga cgccccggac
     3001 gcgggcgcgg gatcgacgag cgtcacggcg gcgccgccgg cggcggtgcg ccaggcggtg
     3061 gccaggccga tcaccccggc gccgatgatg acgatctgca tgcgcgctcc cttcgccggc
     3121 atgatccgga tcaggtcgtg gcggtcggcg gcccgttcag ccgccctctc agcccggtcg
     3181 caccggactc ccgcgctctg tgctgttctg ctgcccccac cttacgacct cggcgaaccg
     3241 ggcaactgcc tggacacctg tccatccccg gatcgccgcc cgttagggtg accttcatgg
     3301 agagggtcat cgtcgtgggt ggcgggctgg ccggcgtgcg cgccgtggag gccctgcgga
     3361 gcaaggggta cgagggtgcg ctgaccctcg tgtcggcgga gcggcaccgg ccctacgacc
     3421 ggccgccgct gtcgaaggcc gtcctcgcgg gcgagtccga cgacacgacc gtcgacgccg
     3481 actgggacgc gctgcgctgc gagctgctgc tcggcgagcg cgccaccggc ctgcggctgg
     3541 acgagcccgg acggggcgga acggtggagt ccacggcggg cgacctgccc ttcgacgggc
     3601 tcgtgatcgc gaccggcgcc gccccgatca cgctgccggg agaggggcgc cagcacgtgc
     3661 tgcgcacgat cgacgaggcg cgcgacctgc gcgcccggct caccgcgggc gcccgcatcg
     3721 tgatcgtcgg ggcgggctgg atcggcgccg aggtcgccac caccgcggcc cgccggggct
     3781 gcgcggtcac cgtcgtggag gcggccgaca ccccgctggc gggcgcgatc gggcccgagg
     3841 tcggcgcgct caccgccccc tggtacgccg aggccggcgt cgaactgcgg accggggtca
     3901 aggtcgcgga ggtgcgcgac gggggcctcg ccctcgccgg cggcggccgc gtcgacgccg
     3961 acgaggtggt cgtcggcgtc ggggtgcggc ccgtcctgtc gtggctggag ggctccgggc
     4021 tgctgctgga gcgcggcgtc gtcaccgacg gctcgttccg gacctacatg ggcgaggagg
     4081 acaccggggc gctgcgtccg gacgtcgtgg cggtcggcga ctgcgccgcc tggtggtcgc
     4141 accgctacgg gcggcggctc ctcgtcgagc actgggacac cgcgctgaac gcccccgagg
     4201 tcgccgccgc ggccctcctc ggccgggacg ccgtgtacga cgccgccccg tacttctggt
     4261 cggagcagtt cgggcgcatg gtccagtacg cgggcgacca ctcggcgtcc gagcggctcg
     4321 tgcgcagggg cgacccgtcc gaccccaggt gggcggtggc gtggctgacc ggcgaccgcc
     4381 tcgacgcgat cctcaccgtc ggccggcccc gcgacctggt gcaggcgagg cgtgtgatcg
     4441 ccgccgggac gccggtggat ccggaggcga tcgccgaccc ggacgtcccc gtccggcagg
     4501 ctgttcgcgc agagcgatcg gcggggacgt aacggctgcg cagcgggttt gagtcttccg
     4561 aaggcgtggt agcaaggggg cgtgacgcag atgcacgcaa ccgttgacag cgcactggac
     4621 ccccgcaccg acgccctggc cggcgagtgg ctcaccctcg gggagaccgc cgagagactc
     4681 gggatcaggc ccaaccggat caagcagctc atccacgagc accgcatcct cgcggtgcgc
     4741 cgcggcgggg agccgatggt gcccgcggcc ttcatcaagg acggccaggt catcaagggt
     4801 cttcccggta ccctgaccct cctgtcggac gccggcttcg acgacgccga gacgatccgg
     4861 tggctgttca cggccgacga cacgctgccg gggacgccgg tggacgcgct caccgagaac
     4921 cgggggaccg aggtccgccg ccgcgcccag gcgctcgcct tctaggccgc cgccggcggc
     4981 gcacgacgca cgtgacacga tcgcggggtc gcgcgcggcg ggtcaccgcg cgcgcgaccc
     5041 cgtgatcacc tgtggaaagg acgtccccgg ccgtgtccag gcacctcccc accgagcgcg
     5101 ccgtcgcgct gcgcgcccgg ctgagccgag cccgcctcta cctctgcacg gacgcgcgcg
     5161 agcgccaggg cgacctgccg gccttcctcg acgccgtgct cgcgggcggc gtcgacctcg
     5221 tccagctccg ccagaagggt ctggaggccc ggcaggagac ggcctacctg gaggtgttcc
     5281 gggcggcgtg cgagcggcac ggggcgctgc tggccgtcaa cgaccgggcc gacatcgcgc
     5341 acgcggtcgg cgccgacgtg ctgcacctcg gccaggacga cctgccggtg cccgccgccc
     5401 gcgagatcgt cggcggcgac atgctgatcg gccggtcgac gcactccggc gagcaggcgt
     5461 cggcggcggc cgccgagccc ggcgccgact acttctgcgc gggcccggtg tggcccacgc
     5521 cgaccaagcc cggccgcccc gcccccggcc cgaagctgct ggagtacgtc gcggcgcagc
     5581 gcgtcgcgcg gccctggttc gcgatcggcg gcatcgacct cggcaacctg gacgaggtcc
     5641 tcgccgcggg cgcggagcgc gtcgtggtgg tccgggcgat caccgaggcc gacgatccgg
     5701 gcgccgccgc ggcgcgcttc gcgcgccggc tggccgcccg gccgctgggc accggctgac
     5761 cgcacggttt gacgcggatc acggtgcggg ccgcggcccc gtcgccgaca atggggatca
     5821 tgagcgtggg acccgacgac gaccgcacgg tcgacctgga cgacgacctg gacgtcctgc
     5881 cggaccagac gtccgacgac accgacgccg gctggggcga gtggcgtacc ggcgacgacg
     5941 acgcgcgcct gctggaggac cgcccgccgc actggtgagc ggccgcccgg gtcaggtcag
     6001 gacgccgagg aggaacccgg ccgccacgac ggcgccgagc gcgaccatca tccgccaccg
     6061 gtagcgcggg atccgtgtcg ggcgcggctt cggcgccggg gcctggccct cccgcagcgc
     6121 ccggacgatc tgcgacgcgg tcgggcgcgc ggcggggttc ttgtccaggc agcgggccgc
     6181 gagctcgcgc agcgggccct gcatgtcgcc gaggtcgggc ttgcgggacg tcacgcgccg
     6241 catgacggcc gcgctcggcc cggtgccgaa cggcgggcgc cccgtcgcgg cgaacaccat
     6301 cgcggcgccc cacgcgaaca cgtcggcggg cggcccgacc ggctcgtcct cgatctgctc
     6361 gggcgccatg taggcgggcg tcccgaccgg gccggtggtc agcggggtcg cgtcggcggt
     6421 gcgggcgatg ccgaagtcga tgaccttggc gccgtccggg ccgagcagca cgttgccggg
     6481 cttgaagtcg cggtgcacga tcccggcgcg gtggatcgcc gccagcgcgg cggcggtccg
     6541 cagcgcgagc ttgcggagcc gcggcgggga gagcgggccg cggtcggcga cgacgtgctg
     6601 gagcgagggc ccctcgacga actcgctgac gatgtagggg cggtcgccgg tcatgtcggc
     6661 gtccaggacg cgcgcggtgt gccgcccgga cacccgcagg gccgcgtccg cctccttggc
     6721 gaagcggctg cgcgcccgct gcccggccgc cacgccgccg cgcagcagct tgacggtgac
     6781 gagaccgccg tcgccgtccc ggccgaggta gacgacgcct tggccgccct cgccgagccg
     6841 cccgagcagc gtgtagacgc cgaggccgca cgggtcgtcg gggccgagcg gggcgccggc
     6901 ccggtggtcg cggccgtgcg cgggccgggc cgggacgcgg cccggccccg ggtgcgcctt
     6961 ggccgggcgg ccggcgtgcg cgccgtgggg ctggccggcg cgggcggcgc ggccggggcg
     7021 gggggaagag gatcgcgggg gatgggggtc cgtcctcccg cgggaggtgt cgtgcggcac
     7081 tgggggactc cgactcggcg ggggcggacg aagatctccc catttgtacc gcgtaatcgg
     7141 aacgtggggc aggggaaccg agatcttctc cgtcagcggc acgccccgag tgccgcggag
     7201 ccgacgatcc gccgggacga ctcgcccacc atgatcttgt agcagccggc ggcgaccttc
     7261 cacgccttcg ccacctcgtt ccagtaggcg aacgagcgcg acgacagcgg gaacgtcacc
     7321 ttcgcgctcc gcccgggcgc gagggcgacc ttggcgtatc ccttgagctg cttgggcggt
     7381 tgcgggacct ccgcgcccgg cgacggcatg ccgatgtaca gctgcggcac ggcgaccccg
     7441 gctcgtcgac cggtgttggt gacggtcacc tgcacggact tggaggtcgc gaccagcccg
     7501 ctgtaggcga acgtggtgta ggacaggccg tgcccgaacg ggaaccgggg cgcgattccc
     7561 ttcgcgttgt agtgccggta gccgaccatg acgccctcgg agaacgtggt gttcttgtcg
     7621 agaccggggt actgcgccgg attcccggac gcgggcgcgt cgttctcgtt ggcggggaac
     7681 gtcacgggaa gccgtccgcc ggggtccacg tccccgtaca ggacgcgggc caaggcgtcc
     7741 cccgcctcct gacccggata ccaggcttcg acgatgcccc tcacctgtcc cgcccagggc
     7801 gtcagcacgg gcccgcccgt gttcagcacg acgaccgtgt tgggattggc cttggcgacc
     7861 tcggagatca ggccgtcctg gtcgcccctg agcggctcac cgcatcgcag cgtcaggcac
     7921 gacttgtcga agaactcgcc ctggctgtcg gtcgcgaaca cgatggcgag gtcggcggcg
     7981 cgggccgtgg cggcggcgcc cccgcggtcg tcgccgtcgt ggtaggtcac cctggttccg
     8041 gagcccgcgc ggcgggagat gccgtcctgc gcgctcacgg tcgcgaacgg gacgaccttc
     8101 gccgagccga agccgctcgg gctctgccgc gcggcccgcc cgatcagcgc gatcgacccc
     8161 ggggcccgga gcgggaggac gccgtcgttc ttcagcagcg tgatcccgcc ctcctcgacg
     8221 accctggcgg cgttccggct cgccgtccgg tcggcgcggc cgaggtcgtt ggggtacgcc
     8281 tgccggtcga acaccccgaa cctgaacatc gtccgcagga cggcgcgcac gtgtgcgtcg
     8341 atggcggcct gcgtgacctt cttctgcgcg acggccagct tcagcaggaa cgcgttgtac
     8401 ttcatgccga agggcagttc catgtccagc ccgccgttgg cggcgccggc ggcgtcctgc
     8461 acggcggtgt ggtcggacgg gacgaacccc gtgaaccccc actccgaccg caggatcccg
     8521 ttgaggacgg cgtcgtcctg gcaggcccac cggccgttca gcttgccgaa cccgcacatc
     8581 accgtcgcgg tgcccgcgtc cttcaccgcg gcctcgaacg gcggcaggta gatctcgcgg
     8641 agcgtgcgcg ggtcgacgtt catgccgagc gacagccggt cggtctcctg cgtgtagacg
     8701 gccatgtgct tgaccgaggt catcacgccc tgcgcctgcg cgccccggat ccacggcacg
     8761 ccgagggtcg ccgacaggta ggggtcctcg ccgaacccct cgaacgtccg gccgttgcgg
     8821 ggcgtgcgca ggacgtccac ggtcgggccg aagaccaggt cgttgccccg gtgcctggcc
     8881 tcccacgcaa ccgtcccgcc gtacagccgg gccgcctccg ggtcgaaggc cgccgcgagc
     8941 gcgatcggcg cgggcagcgc cgtcgccgtg ccctgccgga cgccggccgg gccgtcggcc
     9001 atgcggaccg gcgggatgcc gagccggtcg atcccgtcgg cggtgtcggc gtgcgcgttc
     9061 tcggagaaac cgccgagcgg cccgccgagc ggatcgtccg acgcgagcat cgagatcttc
     9121 tcgtcgtcgg tcatccgcgg cagcagcagc gccgcccgcc ggtcgggcgc cagcgcggcg
     9181 tcgcaccacg gccgccgggc caggtcgccg cagcgcccgg ccgccgcccg cgcctcgccg
     9241 ggcgcggacg ccgcggtcac caccgccgtc agggccagcg cggaggcgac cgcgagcgcc
     9301 gccggcagcc cgcgccccgg cctcatccgc ccgccccctc ctcgcgcgga acctgatcct
     9361 cgtgccggcc gtcatcctcg ttctggacgc gcagggcgtt cagcgtgaag gcgaccatgt
     9421 ggtagtggcc gatcagcatc accagctcga tcagctcgtg ctccccgaag cgcgtggcca
     9481 gctccgtcca cgtcgcgtcg ctgaccgtgc cgctctcgtg cagctcgtcc gcggcggcca
     9541 gcaccatgcg gtcgtcgtcg ctccagccgt gcccgtccgg atcctcgcgg agtgcggcga
     9601 tctcgtcctc ggtgagcccc gcgtccagcg cgacccggcg gtggtggtcc cactcgtacg
     9661 cgcaggaccg gtggtgcgcc gtgcgcagga tcgccagctc gcggtcgcgg gcgcccagcg
     9721 tcccgttcat cagcagcatc gagccgaacc cgatccacga ccggaacagc tccgggtgcc
     9781 gggcgagcgt ggtgatgacg ttgaggggcc cgatcgtctc ggtcacggcc ctgaccacgt
     9841 cgtcccactc ctcctcgggg agcgggtcga agcgcgggac gcggtctcct ggggtgtcgg
     9901 cgcacatggc gacatttctg ccaccaatca gtgggaaagt tctagtgcgc cggggaaagt
     9961 tggccgaatc gtgtcacggg aggcgcgtgc ggcggcgggc tcacgtgctg cgcgtggtgg
    10021 ccgccaccgc gagctccgcc agcgcctccc gggcaccggc ggtgacgggg gccgcccgca
    10081 gggccttctc cgcctcgcgc aggtagcgct cgatcatggc ctcgcacgcg gcgaggcccc
    10141 cggtctcctc gatgatggcg cgcagctcgt ccacgccggg gcggtccagc gccgggtcgc
    10201 cgagccggcg ctccagcgcc gcggcctggg ccgcggaggc acgttccaag gtgagcgcga
    10261 ccaggacggt ccgcttgccc tcgcgcaggt cgtcgccggc gggcttgccg gtctcggccg
    10321 ggtcgccgaa cacgcccagc acgtcgtcgc ggagctggaa ggcgatgccg agcggcagac
    10381 cgtagccggt gagcgcggcc gccacgtcgg gacgggcccc ggccagggcc gcgccgaggt
    10441 gcagcgggcg ctcgatcgtg tacttggcgc tcttgtactc caccacgcgc agcgccgtcg
    10501 cgacgttcgc ctggcggcgc gccccctcca gcatgtcgag gtactggccg cacatgacct
    10561 cggtgcgcat gaggtcgtag accgcccggc cgcgcagcct gctcgcgccg tccagcccgg
    10621 aggtctcgaa catctcgccc gaccaggcca ggcacaggtc gccgagcagg atggcggcgc
    10681 cgccgccgaa ggactcggcg tcgcccggcc acgcctgcgc gcggtgcagc gcctcgaagc
    10741 gccggtgggc ggacggctgg ccgcgccggg tgtcgctgga gtccatcacg tcgtcgtgga
    10801 tcagcgcgct cgcctggagc agctccaggg acgcggcggc ggccacgatg ccgggcccgt
    10861 cctcgccgcc cgccgcgcgc cacccccagt agcagaacgc cggccgcagc cgcttcccgc
    10921 cgccgagcag ggcgtccagg gccgacagca gcggtgcgag gtcctcgctg atggcgcgca
    10981 gcgcggggcg ccggaggtcg acgaaggcca gcagcgcctc gtcgacctcc ttgcggatcc
    11041 gggtggtcga catgccgaga tcgtatccac ctgggtgctt tccaccctcc atcacgagcg
    11101 tgtgatgtca ctagatcttc agaaatatgg acataacgca tgttgggtgt ggcgagcatc
    11161 acgcggatcg gcggccccgg gcggtgccct ccgctgccct ccgctctccg ctgttccggt
    11221 ccgcccgggc ggcgcttctg taggcttggg gaatgcgacg cgtacgcccc gacaggcccc
    11281 ccaccgtccg agaactgctc gcttcgggcg agcgctcgtt ctcgttcgag ttcttcccgc
    11341 ccaagaccga caagggcgcg cggaacctgt ggcgtacgat ccgcgagctg gagtccctgc
    11401 acccgacgtt cgtgtccgtc acctacggcg cgggcggcgg cacccgcgac acgaccgtcg
    11461 acatcgtcga gcgcatcgcc accgacacca ccctcacgcc ggtcgcgcac ttcaccgccg
    11521 tgaaccactc gcaggccgag ctccgcaacc tgatcggccg gttcgccgcc gtcggcgtcc
    11581 gcaacgtgct ggcgctgcgc ggcgacccgc ccggcgaccc gatgggggag tgggtcaagc
    11641 acccggacgg cgtcgagtac gccgccgaac tggtccggat gatccgctcc tacggcgact
    11701 tcagcgtcgg cgtcgccgcg ttcccctaca agcacccgcg ctcgcgcgac atcgagagcg
    11761 acacccgcca cttcgtggcc aagtgccggg ccggcgccga ctacgcgatc acccagatgt
    11821 tcttccgcgc cgaggactac ttccggctgc gcgaccgcgt cgacgccgcc ggctgcgacg
    11881 tgccgatcct gcccggcatc atgccggtca cccggctcag cacgatcgag cggtccgagc
    11941 agctgtcggg cgcgccgttc ccgcccgagg tcagggcccg cttcgaggcc gtcgccgacg
    12001 acccggaggc cgtccgccgg ctcggcatcg agcacgcggc cgagctgtgc tgcgaactgc
    12061 tcgaccaggg cgcgccgggc atccacttca tcacgttcaa ccagtccacg gcgacgcgcg
    12121 aggtctactc gctgctggac ggcgccgggt acggcgccag gggcagcgtc ccgcccatca
    12181 ccgcgtagcg gggtccgccg cccgggaact cgaagtcggt cagcaggtcg accatgccga
    12241 ccgaacggta gagggtgcgc gccggggtgt ccggcctcct gtcgagcgtc gacagcacga
    12301 ccgtccgctc cggccgcccg ttgcagagcg cggtgagcag ggcccggccg aggcccctgc
    12361 cctgcgcctg cggatggacg tgcagttcgg cgacctcgaa ggcgttctcc agccacgagt
    12421 cggcgtgctc gggcccctcc cggtcggaca gcgcctggtg gacgacgtcg tgccaccact
    12481 ggccgcgcgc cccgtggaat ccgtaggcga acccctggac gggcgccggc atgacgggca
    12541 gcgctccgcg ccgctcgacc acgcacgcgc ggaaccccgg atacgaggca tgccgctcca
    12601 tgatggtgtg ccggcccggg agctgctcgt tcggcggctc catcgcggcc gcgtacacgt
    12661 ccagcatggg gctcagcctg cgtaggaagg cacgttcgtc gatctcgcgc agcttcgggt
    12721 ccctcacccg acagagacta gacccgcgtg acggtccgct gggtgacgga aagccgatcg
    12781 tagaggtccc agaggatccg gtcggcggcc ttccgcagtg ttccgcggtt ggcgtcgagc
    12841 tgcccgcccc actcgcgcgc ctccgggccg agccacgcgt ccgtcccgcc gagcgccttc
    12901 acgggcccgt ccagtgcctg gcggagccgg tcgatgctgc cgtaggcgtc cgcgtacgcc
    12961 tggtagagct gctggtactc cggattcggc tgctcggcgg gcgacagccg cgccgaagcg
    13021 gcgcccgtga tcggcggggg caggctgccg ggaggcggtg gggcggccat ggcgacctct
    13081 caggcggtgg cggtggacgg gtgcaggtcg agcctggcga tggcctcgcg cgtgcggccg
    13141 ctcatgtcgg cccccaggag cacctggacg gcgacgggac ggaccccggc gtggtcggcc
    13201 ccggccagga aggcgcgcag ccatctcacg tccatcgtca gatggtggct ggacgtgccg
    13261 agggactgct gcacggcctc cagcctcgcc ttgtccccct gggcggcctt cagcagatcg
    13321 gcggcgcccg ccgggccgag acgctcgtac agcttctcgg tgtagtcggg gtcgccggcg
    13381 ttggcctcca ggtgtctcca caccgggtcc gggacggggc ggccgtgctg gacggacgcc
    13441 gccacggaca gtgcgtcggc cttggcggcc cgggcggcgg ccggccggtc ggggaagccg
    13501 ccgaggtcgc cggcgccgtg cggggtcggt cgcggcgccg ccttcgcggg cgaggtccgg
    13561 tgcggcggcg ccttcaccgg gcgcggcgtc cccaccgggc cgccgccggt cttgcgcggc
    13621 accggagccg gggtgggcgc cggcggcatg tcgatgccac cgccagggga gggatgcgtg
    13681 accgcgaagt tgtaccggcg cgtcagcatc ccgagctgct cggcggccca ccgcgccacc
    13741 tcgtcggcct gcctgtaccc ggccgtggag acgccgggcg gcgggcgatg gccgttcagc
    13801 cacccctgga tcgcgttctg cgcgtcctgg agctgcctga tgacctggtt gagcgcgggc
    13861 gggtcgatcc cccggaactc cgggtcgcgc gccgccggac ccgtccgcat ctgcgtcgcc
    13921 atcacccctc cggtgctcgc catcgccgtt tcccgactcc ccagaatcac actggtgtca
    13981 ctggctgtcg agtgccctgc ccaccgattc ggcatcgcgc gccacgacgg cggtctcgtc
    14041 cgccacgacg atcggacgct ggatcagcac cgggttcgcc accatgacct cgatccagcg
    14101 ggcccggtcg cgttcgaggt ccctgagccc gagctccttg gcgaccggct cgttcagccg
    14161 cgccacgtcc cacggctcgg cgccgatccg ggtgaggaca tcgtccaact cctgcgccgt
    14221 gggcggctcg tccaggtagc ggcgctcggt gtaccgcacg ccggcctcgt ccagcgcggc
    14281 cttggcggcg cggctcttcg agcagcgcgg gttgtgccag agttccatca ctccacctcc
    14341 gccggggctc ccccggtgat cctcagcagc tcgccgtacg acgtggggaa gacggtgtgc
    14401 gggtgcccgc ccgccgccca cacctcgtcg tacctttcca gccagatgtc caccagtgtg
    14461 cggatcggct ccggatggcc gaccggcgcg acgcccccga tcggctggcc ggtcgcctcc
    14521 cggacgaact ccggcgacgc ccgccgcacc ttcgccgcgc ccaccagcgc cgcgaccttc
    14581 accgtgtcga cgcggtgcgc gccgctggtc atcaccagca gcggcgaccc gtcggcgtcg
    14641 aacaccaggc tgttggcgat cgcgccgacc tcgcagccga gctgctcggc cgcggcctgc
    14701 gccgtcctcg cggagtcggg cagctcgacg atcgctcccg ccgcgcccag gtcgagcaga
    14761 gccttcgcga cgatttcggc attcggatgc atgggtagaa ctttaaggtc agtgcatgcg
    14821 agggagagcg atcgacgtgc ggaagagcgc ggttctgctg atcggggccg tcgtcctgac
    14881 gggctgcaac gacatcgacg cggcggggtc cgccccgtcg aaggaggcgc cgaaggggac
    14941 gccgtccaag gcgccggcga cgcccacacc gagccccggg caccgcaaac tgaaaccggg
    15001 cgccaagggg cccgacgtcc aggcgctcca gcggcgcctc aaggcattgc actacgaccc
    15061 cggaaaagcg gacgggaagt acgggccgtc cacgcagacg gccgtgtggg cgttccaggc
    15121 ggtgaaccgt ctcaagcaga agagcaccct ttccgcctcg ttctggaagg ccctggacgc
    15181 tcccaaggag ccgcggccgg tggccgagaa gcgcgagaag aaccgcgtcg acgtggatct
    15241 gaagcgccag tacctcgtcc tctacaagag cggcagcccg cggctcatca cgcacgtgtc
    15301 gtcgggttcg ggggagtact actgcgccaa ggaccggggc gcgaccgtcg cgcgctgccg
    15361 ctacgccacg accggcacgg gcgacttccg gacgggacgc cgcgcctccg gctgggagac
    15421 ctcgccgctg gggcagctct acaaccccat ctacttcaac ggcggcatcg cgttccacgg
    15481 cgccctggac gtgcccatgc accccgcctc gcacggctgc gtccgcatgc cgatgcacat
    15541 cgcccggtac ttcccggacg aggtcggcac gggcgtcccc gtgcatgtca ggcggcctcg
    15601 ctagcctccc cgcgggagcc gcgtccgggc cgctgtcaac cccgctgacc tgcgggatac
    15661 gacacgcgtt cgaacacgtt gacgaatcgc cgtcagggcg gtttactgtg aagcgcgtcg
    15721 aacttatgtt cgatgtggtg cgggactcgc ggcccgcgcc agggcgacgt ccccgccgat
    15781 tgcggtgttt cggcgggacg gacggccggg cggagtgagg ggaagctctc cgcccggccg
    15841 gcccgagccc cggaaggagg cagacatgtc cggaacgatg accgcacgcg gagtccactc
    15901 cgcagcccag tccgtcccgt cccccagtcc tcgcccacgc caccggccga tgcccgcgcc
    15961 gcgtccggcg cacacggccg tcgggcagtt gcacgccgcc cgcatgggcc tcgccgaggc
    16021 ggccgaggcc acctcgcccg ccgtccgcta cgtgtgcgcc cacctggcgg cgctgcgcgc
    16081 ggccgccgcg gtcctggcgt ccaaggagcc tttggagacc caccgccgcg gccgtccgcg
    16141 cagcgtctgg gtgctgctgc ccgaggccga gcccgcgctg cgcgagtggg ccgccttctt
    16201 cgccgccggc gccgacaagc gcgccgccgc cgaggcgggc ctgccgcgcg ccgtcacccc
    16261 gcgggacgcg gaggagctcc tgcacgacgc cgaggtcttc gtcaccctcg tcgaggacac
    16321 cctcggagtc gacgggcagc ccacgctccc cgtccccgaa gccggctgag ccaccccgga
    16381 ggccgtcccc ctccccgggc cggcccccgc cggaggccgg gacgccgccc cgccatgggg
    16441 agcggcgtcc ccctccggcg gccggaccga tcgcgccggc ggggccgcga ccccccgagc
    16501 cggtccctcc ggcgcggtct caccccggtc cccgcgcggg cgagggccgg ttggtagaca
    16561 tggccggatg accgacctac tgccgctgga cgggatgcgc gtcgtcgagc tgtccagctt
    16621 cgtcgcgacg ccgctgggcg ggatgaccct ggcgcagctc ggcgcggacg tcatccgcgt
    16681 ggaccagatc ggcggcgggc ccgacatcga ccggtggccg ctcgcgccgt ccggccggag
    16741 cctgtactgg gccgggctga acaagggcaa gcgatcggtc gccctcgacc tgcgctcgcc
    16801 cgaaggccgc gaactggtcg ccgcgctcgt cacggagggc ggtgtcgtcc tgaccaacgc
    16861 gccgccgcgg ccagggttgt cctacgagga gctgaaggcc gcgcggcccg acctgatcca
    16921 cgtccggctc caggggacgc gggaaggcgg caacgccgtc gactacacgg tgaacgccac
    16981 catgggattc ccgtcgatca cggggcccgc ggacctggag gcgcccgtca accacgcgct
    17041 gcccgcgtgg gacgtggcgt gcggcctcta catggccgtc gggctgctgg cggcggaacg
    17101 gcaccggtcg cgcaccggag agggccggcg gatccaggtc gcgctccagg acgtcgccct
    17161 ggccaccgcg gggaacctcg gctacctcgc agaggctcag ctcggcgagc ccagagcgcg
    17221 cctgggcaat cacctcttcg gcgacttcgg gcgcgacttc gccacgtccg acggacgggt
    17281 catggtcgcg atcctcaccg cccggcactg gcgcgacctg gtggaggcga ccggtctcgg
    17341 cgaggtggtc gaggccctcg gacgcgccct gggcgccgac ttccgccgcg ccggcgaccg
    17401 ctacgcccac cgcgaggcgc tcggcggcgt gctcgcgtcc tggttcgccc gccgcacctg
    17461 cgagcaggtc gcggacggcc tgcggcggac gtccgtcctg tggtcgcgct accgcgactt
    17521 cgcggaggtg gccgcggggc tgcgggacga gccgctcatg gcaccgctcg accagccggg
    17581 cgtgggcccg cacctggccc cgggctcgcc cgtgcggctc ggtgagacct ccccgccccc
    17641 ggtcccggcc cccaccctcg gcgagcacac ggacgaggtg ctccgggacg tcctggccct
    17701 gccagccgag cgcgtcgagg ccctgcgggg caacgggacg atcattggct ggtgacgcgc
    17761 gcgggctcgc gtcggcggcg gcgccgatag gcgacggcca gggcggcgag gagcggggcc
    17821 caggccacga gggggaggta gaggaacccg accacggtgt ggccggccgg ggtcatgtcg
    17881 tcgcccggca tgctccacca ggccgccaag ggcgtccaca gcacggcgag gacggcgaca
    17941 ccggcccacg cggggatcag gaccgccgag ggcgcgatgg tccggccgcc gatgaccggg
    18001 atccagcggg ggaccacctc gccccatcgc tgcacgagtc cgagggccga cagggcggcg
    18061 ccctcgctga ggacggcgag caggaccagg tagccgggtc cccagaagcc gggcgggcag
    18121 accgtccggt agccctcctc ggtgtatccg aggtggaggc ccagggcgag gccgagccgc
    18181 cagatgccgg acggcagtgc gagcagggtg atcgtgtgcg cggccaggtg cgcccatcgg
    18241 ggggcgggcc gcaccgccgg tcgcgcggcg tgggcgggac gggagagcac ggtcatgcgg
    18301 acgagcatgt ccgcccgggg gcggccgatc ctcccgccgg aggccggacc gggtccccca
    18361 caggggggag gagggtggtt cgtcccggta tgagattgtt aggggagcga acttcaggag
    18421 ggcacggtgg cggggcgggg cgggcggggg ctggtgccgc tgctggcctt cctcggcgtg
    18481 atggcgtact cgctctcgat ggccgtggtg acgcccgcgc tgccgcagat ccagcacggc
    18541 ctgcacacga ccccggcggg agcggcgtgg gcgctcacgg cgatgacgct gtccgcggcc
    18601 gtcgccacgc cggtggtcgg acggctcggc gacctgtacg gggcgcgccg cgtgctgctc
    18661 tgcgtgctcg ccgtcgccac cgccgggacg gtcgtcgcgg cgctggccgc gacggtgccg
    18721 gtcatgctcg ccgggcgcgt cctcggcggc gtcggcggcg gcgtcttccc gctggcgtac
    18781 acgatcatcc gggacgtcct gccgcccgcc cggcgggccc ccgccgtcgg cctcatgtcg
    18841 tccatgctgg gcctcggcgg cgccgtgtcg tggtgcctgg ccggtccgat catcgacctc
    18901 ctcggctggc ggtggctcct gtggctgccc gtcatcggcc tggtgcccgg cgtcgtcctc
    18961 gcctggtgga tcgttccggc cggacgccgc gacgggtcgt cccgcgcggc ggcgcgcgtc
    19021 gactggtggg gcgccgtcct cttcgccgcc tggctcgtgg ccgcgctgac cgccctcacc
    19081 gaggggatgg actggggctg gacgtccccg ggcgtcctcg ggctgctcgc gctcgcgctc
    19141 gcgggggccg gcgcctggct gtgggtggag ggccgcgtct ccgagcccct gatcgacctg
    19201 cgcctcatgc gggtgcgcgg ggtatggacg gcgaacgccg cctcgctcct gtcgggctat
    19261 gcgctgatgg cgggcggact gctgttccct ctgctcgtcc agctcccgga ggacaccggg
    19321 tacggcttcg gcgggacggc cacgcaggcg gcgctgctcc agctccccgc cagcgtcggg
    19381 atgaccgtcg cgggcatgac ggcgggcctg ctcgaccggc gcgtcggctc ccgcacggtg
    19441 ctgctcggcg gcgcggtgat gaccggcctc ggctacgcgt tcgtggcgtt cgagcacggc
    19501 gccatgtggc acctctacgt cggcggcctg gcgcggggcg tcggcctggg cttcgcctac
    19561 gccgccgtgg cgaccctggt ggtcgccgcc gtgccgccgg aggagaccgg cgtggccacc
    19621 ggcatcaaca cgctgctccg caccgtcggc gcgtccctcg ggacgcaggt cagcgcggtc
    19681 atcgtcgtcg cggtccccgg tgagggcggg ttctccgccg ggttcgcggt gagcgccgcg
    19741 gtcacggcgg ccgtcctccc gctggccctg ctcgtcccgc gcccggggcg caggcgcgaa
    19801 cacggaacgg ggcccggagc ggtgccggac cccgtcacgg tcgtgcggtg aatcgggtgg
    19861 tgcggtgaga caggcggtga atcagaacga ctcgacggcg cggcgcgcct ccgggtcgag
    19921 gacgccccag ccgatcagct cttcggtgag ctcggtcggg gacttgtcat agatgaccgc
    19981 gagtgaacgc aagtcctcct gacggatgga caggaccttt ccgttgtagt cgccccgctg
    20041 gctctggatc gtcgcggcgt agcgggcgag aggaccggcc ttgtctttcg gaagctgctg
    20101 caaccgctca agatcgataa cgagcttggg tgtaggcccg agcgggctcg gcgcggctcc
    20161 gccgggcagc aactcggaaa ccggcacgcc gtagaaatcg gcgagctcgg ccagcttctg
    20221 aacggtgacg gcgcggtcgc cccgctcgta cgaacccacg acgacggcct tccagcggcc
    20281 gcgtgacttc tcctccacac cgtgcaggga caggccctgc tgggtgcgga tggcgcgcag
    20341 tcgcgcgccg agagcctttg catattcaga cggcattctg cggcccccca ggctcacttt
    20401 cgtcgtcgtc ggaccccggc ttgtcaccgg ggggagacag attcgcgaag ccagggggcc
    20461 tcaggactct gtctccaggg atggttacgg acagtgacgg taaaacgggt agggccccag
    20521 gtcaagctga ttggaaaaaa gcggtcgaat ccgcaggact cgatccgggc cgtccggatc
    20581 gcgtccggcc cgtgcgggca ggggcgcggc gggccggacg ggcggccggg gctctcccga
    20641 gcgcccccga atgtgacccc tctcacctgc gaagacgtgg acggtgccgg gtgtcgggca
    20701 ggcgggaccg gctgctaacg tgtgggggac acgacgtcct ttaaggcccg tcccgtgagg
    20761 cggggaagga ggtttcggcg gtgaacgctg ccttcaggca ggagcatcgc gtggcggacg
    20821 gtgacccccg gcccaaggcc gttctggagg gtcccgacat ccggcgcgcg ctgacccgca
    20881 tcgcacacga gatcctcgag cggaccaagg gcggccacga cgtcctgctg ctcggcatcc
    20941 agacccgcgg cgtgacgctg gccgagcggc tcgccggggc gctgcgcgag gtcgagggcc
    21001 gcccggtgcc ctggggctcg ctcgacgtga ccatgtaccg ggacgacctg cgg
//
