LOCUS       NZ_BMQY01000004        21071 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Couchioplanes caeruleus subsp. azureus strain JCM 3246 sequence04,
            whole genome shotgun sequence.
ACCESSION   NZ_BMQY01000004
VERSION     NZ_BMQY01000004.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Couchioplanes caeruleus subsp. azureus
  ORGANISM  Couchioplanes caeruleus subsp. azureus
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Couchioplanes.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 770393)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 64X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014648355.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 03:32:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,801
            CDSs (total)                      :: 6,731
            Genes (coding)                    :: 6,630
            CDSs (with protein)               :: 6,630
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 20 of 101
            Pseudo Genes (incomplete)         :: 93 of 101
            Pseudo Genes (internal stop)      :: 0 of 101
            Pseudo Genes (multiple problems)  :: 12 of 101
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:23:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 299982
            Orig. end                         :: 321053
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMQY01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21071
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="3"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21071
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21071
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11071](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11071)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(591..605)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     gene            complement(999..1727)
                     /gene="lepB"
                     /locus_tag="IEY99_RS16540"
                     /old_locus_tag="GCM10010166_33180"
     CDS             complement(999..1727)
                     /EC_number="3.4.21.89"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /GO_process="GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /gene="lepB"
                     /inference="COORDINATES: protein motif:HMM:TIGR02227.1"
                     /locus_tag="IEY99_RS16540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_33180"
                     /product="signal peptidase I"
                     /protein_id="WP_189204130.1"
                     /transl_table=11
                     /translation="MNDTVSTTKAPRFARRRTAAGLAGVVLIVAAAVFLALRFDVYTVR
                     STAMSGSLEPDERAVQEKVTTSDIQRGDVITFRGGTWEGDPPDAIYAMRVIGLPGDRVA
                     ANPEGQLLVNDKPIAEKYAEGDNRQEGRPFSVTVPAGRYFVMGDNRAVARDSRARIDTQ
                     GSGAIPSDRVEGRLIAIALPVWHFGSLTPGDAFTAVGPTAEAYNLAPLLAAVVCVLAGV
                     LIVISVSGGSVRRRLAGRRR"
     misc_feature    complement(1095..1097)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(1182..1184)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(1720..3999)
                     /locus_tag="IEY99_RS16545"
                     /old_locus_tag="GCM10010166_33190"
     CDS             complement(1720..3999)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014717.5"
                     /locus_tag="IEY99_RS16545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_33190"
                     /product="FtsX-like permease family protein"
                     /protein_id="WP_189204132.1"
                     /transl_table=11
                     /translation="MTWLLTLRLLRGGGWAGLARLILMILGFGVGALVVATAMALPTVL
                     DDRAMRSSDRLPNSAMEENAAFGFTFVTDSWHDERFTRVFLAKVKEAAPPPPGLSRFPA
                     PGEIFASPRALQVMRADPLVAERMPGTVVGTIGPSGLLGPNELYAYVGVVPDDLAGGSA
                     GISFGNATPDQSVAEQLGGVSYELMLLMFIPVSVFLVICGRLAARTRAQRYAALRLLGV
                     RRKQTVRMAATEAAVAGVGGAVLGVLSFNSINRELADSKVLGFTWYAEVSRLDLPTAVL
                     LVVIAAAGAAFLGALGLRQSVKKPLQARASAGRRLTVWMLAPLVVGLGLLLPPLISAQS
                     AADARQGVSDTTAYLILAGIAACVVGTMMALRYAIPLLGHSLRGQRYPLFLRVAGARLA
                     ADPGSLLRLTSGPVLLVLIAGISAGVLRDAALAAGPTVTARTVVIDTRTVATADQRRAI
                     AATPSIATWRLQQSIVEDVPDLSTPEQRVRGIGMTMVMASCDDVRTMVGQPLPDCREGT
                     DYRFGDPALNGTVSEVPAGVTVKFRNETGQEVAYTTPAAFLPIPEADRTPLGENGVISA
                     APQPKFGWSPDLSMTFVIGASGADLERFKSAVQRISPTASMHVKQLNLDALEAYRVHRG
                     TVSFGVIAGLGLCLLAFAVAAVDRMVERRREVVALAVLGVRRRTVRVIQIVQLGVPLVG
                     GILLATAVGYLAGNAWLKVNGRQAGWYNGALDSMYPAIGLSVFVCIAVGALVVGYRIKA
                     EDIRRE"
     gene            complement(3996..4616)
                     /locus_tag="IEY99_RS16550"
                     /old_locus_tag="GCM10010166_33200"
     CDS             complement(3996..4616)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015624522.1"
                     /locus_tag="IEY99_RS16550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_33200"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_229798795.1"
                     /transl_table=11
                     /translation="MALAKASATVSPGELLALVGPSGSGKSTMLYCLAGILQPDSGEVL
                     FNGRDLCRMSDDERSDVRRRHFGFVFQFADLVPELTLRENIELPLTLNGVGRRDRRKRV
                     AELVETLGLQGQAGRRPAFVSGGQAQRAAVARALAHRPAVLFADEPTGALDTENGAVVF
                     NALIELANGSGAAVVLVTHDNALAARAHRVVTMRDGKTDEESW"
     misc_feature    complement(4618..4634)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.05"
                     /tool="antismash"
     gene            complement(4674..5087)
                     /locus_tag="IEY99_RS16555"
                     /old_locus_tag="GCM10010166_33210"
     CDS             complement(4674..5087)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY99_RS16555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010166_33210"
                     /product="hypothetical protein"
                     /protein_id="WP_189204136.1"
                     /transl_table=11
                     /translation="MSKSKNIVAAIGLGSLAALAIGSSAYAYGSGTLDLGDDKMRFKGS
                     YTFNGTYRGGMKVSGTVCDTAADGNGVYGQGKILGYAWSSKVSDGNGSASGCGTESRTF
                     SSNDVNFVSYGWYQICTDDWGSDTCDISSRLNR"
     misc_feature    5079..5092
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.26"
                     /tool="antismash"
     gene            complement(5453..6787)
                     /locus_tag="IEY99_RS16560"
                     /old_locus_tag="GCM10010166_33220"
     CDS             complement(5453..6787)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024910.5"
                     /locus_tag="IEY99_RS16560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_33220"
                     /product="APC family permease"
                     /protein_id="WP_229798797.1"
                     /transl_table=11
                     /translation="MTRHRLGVWQGTATVLGGVLGPGMLVLPHLAAEAAGPGSVLAWAA
                     LILISVPVAFTFALLGLRHPDGGGVAHFAGMAMGRWAYSIAGWWFLAAVPLGTLAGALA
                     GGVYAAQAFGGDGRVAAVFACGLLASAFAANAAGLRTSGRMQVVMVGILLAVLTAAVAA
                     SLPAVRAGRFEPFLPHGLGGVGSAAGVLIFAFVGWEAASHLSAEFAGRRLLTATGLTLA
                     AITMVYLGVAVTVVGSGAASSPVPLTAMLATRIGAAAGPVTTVAALVLTFGAINTYVAG
                     ASRLAVALAGRRLLPHRISSPYRSLVALGAGVAVVGAATLLRPVGLDPLLRATSACLAA
                     VMALGSLAAVRLLPAGPMRATAIAGTALTGLTLLLSGSYVVVPAVVALAGFTARALTRR
                     AGGGRAGADRAGSRGAGAFARRRPEGTQAGPGPDAGRARAGCRQL"
     misc_feature    complement(6830..6843)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.77"
                     /tool="antismash"
     gene            6867..7331
                     /locus_tag="IEY99_RS16565"
                     /old_locus_tag="GCM10010166_33230"
     CDS             6867..7331
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015619746.1"
                     /locus_tag="IEY99_RS16565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_33230"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_189204138.1"
                     /transl_table=11
                     /translation="MDELDARIVGLLQSDARLSNRELARQLGVAPSTCLERVRSLARRG
                     VIRGYHADIDPAALNRGVQAMISVQVRPLSRAVIDTFKASAAQMPEVLSVFVLAGGDDF
                     LLHVGVPDLDAMHAFLLDRLSKRREVTGFRTSVIYQQVSNPAPGLLPGPA"
     gene            complement(7350..8147)
                     /locus_tag="IEY99_RS16570"
                     /old_locus_tag="GCM10010166_33240"
     CDS             complement(7350..8147)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014693337.1"
                     /locus_tag="IEY99_RS16570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_33240"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_189204140.1"
                     /transl_table=11
                     /translation="MTVNASVTFVGNATTVLRLGGFSLLTDPAFGPAGSRVYLGNGLWT
                     KRVLDPVLEVVDVAALDAVLLSHLHGDHFDRAARRDLPSGLPIVTTPQAQRRLRRKRFS
                     DARGLATWETCEWERGGQRLRVTAVPGRHGPGPVDLLLPAVMGSVLELEAEGRCRLRLY
                     ITGDTLHGPWLQEIPQRCGPIDAMLIHLGGTRVLGMLLTMDDRHGVATTELIRPGLTVP
                     IHNDDYKVQKMPVSTYLDRAREAGLTGIRPVERGQTLELPVRV"
     misc_feature    8165..8179
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.15"
                     /tool="antismash"
     gene            complement(8197..8607)
                     /locus_tag="IEY99_RS16575"
                     /old_locus_tag="GCM10010166_33250"
     CDS             complement(8197..8607)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY99_RS16575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010166_33250"
                     /product="SMI1/KNR4 family protein"
                     /protein_id="WP_189204142.1"
                     /transl_table=11
                     /translation="MLAVSWRDVVLAVLPSATLAGAAAPQDVAAAGERLGAALPEDLAE
                     LLCETGGVRGRGGLPVVWPVERIVRDNLALRPGALLLFGGGGADGDELVGCVPADPSRG
                     IVAWERRTGVCRTVATDLADYVTRALAGDDLG"
     misc_feature    complement(8665..8679)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            complement(8784..9203)
                     /locus_tag="IEY99_RS16580"
                     /old_locus_tag="GCM10010166_33260"
     CDS             complement(8784..9203)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY99_RS16580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010166_33260"
                     /product="hypothetical protein"
                     /protein_id="WP_189204144.1"
                     /transl_table=11
                     /translation="MSELSGMSPEERRQLLAEYEALRDDIAVRAVNRDLAALSAADAQQ
                     AAHRDERLAWELLTVLRDAHREEPGNLRLVAQVDQAEAAHAVAREVAETVSRAAEQLAT
                     RALEYAQTDARRLYELGVRIRAARAAEPDIPIPPS"
     gene            complement(9279..9959)
                     /locus_tag="IEY99_RS16585"
                     /old_locus_tag="GCM10010166_33270"
     CDS             complement(9279..9959)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) ClassB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170: metallo-beta-lactamase family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020515040.1"
                     /locus_tag="IEY99_RS16585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_33270"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_189204146.1"
                     /transl_table=11
                     /translation="MREVVDGVFEVGIGYVHVHLVVTDDGVVLVDTGLPGRSARIGRAL
                     HDIRRTIGDVTTVLLTHHHPDHTGGLAEVRRRSGARVVAHRDDVPYVTGEIQAVSRHPV
                     VKLVGLVMGRAEPATVDEVVSEDGAVPVPGFTALHTPGHTPGHMSYLLDRAGGVLFAGD
                     AAGGRRGGRIGSAPKMVSADLDAQRRSVARLAELDFDHAVFGHGRALTGRAVEAFRAYV
                     AADR"
     gene            complement(10001..11071)
                     /locus_tag="IEY99_RS16590"
                     /old_locus_tag="GCM10010166_33280"
     CDS             complement(10001..11071)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287901.1"
                     /locus_tag="IEY99_RS16590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_33280"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_189204148.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.1e-46, bitscore:
                     154.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVGTAAQTDAAGLARRCEAALVAYLDRQRPHWPDGTPRGVLDAV
                     RRFVLADGKRLRPMFCYWGWRGAGQPDGQAIVAAAAALELFHAFALIHDDIMDGSALRR
                     GQPTVHRHFADLHARHRWRGEAVRYGQSAALLCGDLCAAWADHMFHDCGLPVEWIHRGY
                     RMFTAMRTEVIAGQYLDLVSGVGHGSVAGALTVIRMKAARYTVTRPLQIGAGLAGAGPR
                     LQAALQAFGDPLGDAFQLRDDVLGVFGDPAVTGKPVLDDLREGKPTAMLALARDRADRA
                     QHARIRELFGDPGLDEAGAGELRAIIEATGARDGIEELIGRRAAAATAALDRAPLTPDA
                     RAALATLAASVVTRHR"
     gene            complement(11068..12450)
                     /locus_tag="IEY99_RS16595"
                     /old_locus_tag="GCM10010166_33290"
     CDS             complement(11068..12450)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475570.1"
                     /locus_tag="IEY99_RS16595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_33290"
                     /product="alkaline phosphatase family protein"
                     /protein_id="WP_189204150.1"
                     /transl_table=11
                     /translation="MRPVVVLDVVGLTPRLLRHMPRLTRLAEAGFQAPLGTVLPAVTCT
                     VQSTFLTGTLPSGHGIVGNGWYFRDLGEVLLWRQHHALVRGEKVWDAARSLVPGYTVAN
                     VCWWYAMGAPVDWTVTPRPIYHADGRKDPDCYTYPPQLHDTLTAELGTFPLFSYWGAKA
                     GIASSAWICGAAQRIMAAHDPDLTLVYVPHLDYDLQRHGPSAPQAARAAAELDATLGPL
                     LDAAARRGAVVAVVSEYGITDVSRPVDVNRLLRAEGLLHVYTQAGMEYLDPWTSRAFAV
                     ADHQIAHVYVASADDVPAVAKLCAGLPGVAEVLDRPAQAAHGLDHERSGELVVVAEPDS
                     WFTYYYWLDDAAAPDFARLVEIHRKPGYDPAELFFDPAGPAAARGRAALALLRRKLGLR
                     YTMSVVGLDAGARAVRGSHGRPPTDPADAPVLLCSDPAAQRPAVAATEVKGLLLELAGL
                     RS"
     gene            complement(12447..13598)
                     /gene="eboE"
                     /locus_tag="IEY99_RS16600"
                     /old_locus_tag="GCM10010166_33300"
     CDS             complement(12447..13598)
                     /codon_start=1
                     /gene="eboE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287903.1"
                     /locus_tag="IEY99_RS16600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_33300"
                     /product="metabolite traffic protein EboE"
                     /protein_id="WP_189204152.1"
                     /transl_table=11
                     /translation="MRLYHPDGTTVHLSYCTNVHAAESLDGILAQLDTYAVPIRERLGA
                     DVLGLGLWLAAPVAAGLAGAPADRRRLRRALDARGLEVVTLNGFPYQAFQEPVVKHAVY
                     QPDWTRPQRLAYTLDLARILTDLLPGDAARGSISTLPLAWREPWDADRAGACRRALDDL
                     ARGLHELPRPVRVAFEPEPGCVVETTAEAVALLGEADTSVLGVCLDLAHLACAWEEPAQ
                     ALRRLRRAGLPVVKTQLSAALASADPRRDAAVLGEYAEPRFLHQTRGSAGLAADDLDEA
                     LATPGGDAQPWRVHYHVPLHQAPVPPLRSTVDVLAAALRELLGGDTAGCDHLDVETYTW
                     HVLPPASRPAGPAELASGIAAELFFARARLAALGLATAQGVPS"
     gene            complement(13598..14446)
                     /locus_tag="IEY99_RS16605"
                     /old_locus_tag="GCM10010166_33310"
     CDS             complement(13598..14446)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007072424.1"
                     /locus_tag="IEY99_RS16605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_33310"
                     /product="TatD family hydrolase"
                     /protein_id="WP_189204154.1"
                     /transl_table=11
                     /translation="MRVFDPHIHMTSRTTDDYRRMADHGIRAVVEPAFWLGQPRTNPGS
                     FADYFDSLLGWEPYRASQFGIRHHATLALNPKEANDPRCKGVLDLLPRYLDKDGVVAVG
                     EIGYDAMTPAEDEAFAAQLELAVRYELPALVHTPHRDKAAGTRRSLEVVAACGIDPGMV
                     AVDHLNEVTVAMVRDSGCWLGFSIYPETKMSPSRMVEILTQYGTERVLVNSAADWGHSD
                     PLLTVATGRAMLEAGFTADEVDRVLWRNPAEFYGRSGRLDLSPPDGSGAYAGSSIARGG
                     S"
     gene            complement(14446..15042)
                     /locus_tag="IEY99_RS16610"
                     /old_locus_tag="GCM10010166_33320"
     CDS             complement(14446..15042)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475567.1"
                     /locus_tag="IEY99_RS16610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_33320"
                     /product="EboA domain-containing protein"
                     /protein_id="WP_189204156.1"
                     /transl_table=11
                     /translation="MTLEELRAVVAAVPGKAWFDEAEARVRADPDSAGPLFARAGRKLG
                     RQPLPERPGWTAGQAGRVLLLLAVAAADRVAELYWYGDSAERLAVLHALPLLDIGAAGV
                     PLAEDALRSNDPRLVAAALGPYAAHLDAATWRQGVVKCVFMGIALSGVDRLDDRTDAAL
                     VAMLAALATERAAAGRRLSADAVALLNRHLLRKED"
     gene            complement(15039..15884)
                     /locus_tag="IEY99_RS16615"
                     /old_locus_tag="GCM10010166_33330"
     CDS             complement(15039..15884)
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018783815.1"
                     /locus_tag="IEY99_RS16615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_33330"
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="WP_189204158.1"
                     /transl_table=11
                     /translation="MSALRYGYGTNGFAGHRLTEAIEVIAGLGYRGVALTLDHGHLDPF
                     APGLARRVAAVADRLRDRDLGVVVETGARYLLDPWRKHAPTLLHDDRKLRLDFLRRAVS
                     VAADLGAEAVSFWAGTRPAEVDERTAWRRLVDGCAEITGVAAALGVPVGFEPEPGMLVA
                     DLAGWHRLRGELGAPAAFGLTLDIGHCRCVEPEPVPDCVAAAVPYLVNVQIDDMRRGVH
                     EHLELGTGEIDFPPVLRALIDGGYRGLVAVELPRHSHAAPTVARESLAFLRAAEREVPR
                     "
     gene            complement(15881..16729)
                     /locus_tag="IEY99_RS16620"
                     /old_locus_tag="GCM10010166_33340"
     CDS             complement(15881..16729)
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014444660.1"
                     /locus_tag="IEY99_RS16620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_33340"
                     /product="SCO3242 family prenyltransferase"
                     /protein_id="WP_189204160.1"
                     /transl_table=11
                     /translation="MKAPLRALAELVRAPAALSVPGDVVAGAAAAGTLGARSAGLAAAS
                     VCLYWAGMAANDWADRDLDAVQRPERPIPSGRVSPPVALGVAAGLTAAGLAIAGRAGGS
                     RALTAAVPLAAAVWAYDLRLKDTAAGPAGMAACRALDVLLGASAGAAVRALPTAATIAV
                     HTYVVTVMSRHEVAGCPTPSLPAAALATTTAVAGVTAARGGPAAALLAGRYAADVGRAQ
                     AAVIADPRAARVRAAVGAGITALPALQGALTAGAGRTLAGLAVAAAAPLGRRLARRVSP
                     T"
     gene            complement(16726..17862)
                     /locus_tag="IEY99_RS16625"
                     /old_locus_tag="GCM10010166_33350"
     CDS             complement(16726..17862)
                     /GO_function="GO:0004512 - inositol-3-phosphate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006021 - inositol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018255471.1"
                     /locus_tag="IEY99_RS16625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_33350"
                     /product="inositol-3-phosphate synthase"
                     /protein_id="WP_189204162.1"
                     /transl_table=11
                     /translation="MRTGVWLIGARGSVAVTALTGALALRARLAGPTGCVTELPELRGA
                     PLPGWADLVFGGHDVVTLPVTKKAEDLAAAGVLPGRLVAALADELGRAEQDLRPLPDGG
                     TQAWIAGAIAADLRDFRRRHALERVVVVNVAATEPAVARHGAHASLAALREALAGPEAV
                     LPPSSLAAYASFVAGCSFVDFTPSTGARLPALAELAAAAAVPYAGHDGKTGETLVKSVL
                     APMFARRHLRVTSWSGVNLLGGGDGANLADPAANAAKVASKQRVLGDALGYRPEGTSRI
                     DHVAELGDFKTAWDLITFAGFLGTRMRMEFTWHGCDSALAAPLVLDLARLTAAAHRAGR
                     HGPLTELGFFFKDPLGDGPCALAAQWDALAGFAAGLGR"
     misc_feature    complement(17921..17939)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.66"
                     /tool="antismash"
     misc_feature    17968..17982
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.67"
                     /tool="antismash"
     gene            18049..19272
                     /locus_tag="IEY99_RS16630"
                     /old_locus_tag="GCM10010166_33360"
     CDS             18049..19272
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF018884.5"
                     /locus_tag="IEY99_RS16630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_33360"
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /protein_id="WP_189204164.1"
                     /transl_table=11
                     /translation="MIVEADPWYGLIVELLDRSHLWRPEDMGGVLDGAAERLGLRMTVY
                     VADAEQRSLRPLAVPGRSAPAPLPIDAHAAGRAFSLVESVVADGRRWVPMVNGTDRIGV
                     VEVATPDGTAPDERLARPCEVVSGLVGHLITTTLPRGDHLHRARRSRPMTAGAELLWQL
                     LPPLTVSIADFAVAAVLEPTYDVGGDAFDYTVDGRRPQFVVLDAAGHGLKAGLAAAVAL
                     ACLRAARRSGGDLPDQARAADEELLRQFPDARFVTAVLAELDLDTGVLRYLNAGHPPPL
                     VLRDGAVVETLAEGRRLPLGIADPRATCAEITLRPGDRLLLYTDGVTEARDAAGVPFGQ
                     NRLADSLERHAAEGLPIPETLRRLSHTVLAHQSGPPADDLTLLLVEWSAGAARRTVPPT
                     SRGGEQAA"
     gene            19269..19625
                     /locus_tag="IEY99_RS16635"
                     /old_locus_tag="GCM10010166_33370"
     CDS             19269..19625
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013868.5"
                     /locus_tag="IEY99_RS16635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_33370"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_189204166.1"
                     /transl_table=11
                     /translation="MNPDILSVTFHDPADGVRVLSVAGEIDHDSVEVLRDAVERALADG
                     RDRLVCDLSAVPFCDSGGLSLFVETHRRATARGGWLRLAGPQDQVRFVLDVANLDRYLG
                     VHPTLDEALSAAGQ"
     gene            complement(19645..20283)
                     /locus_tag="IEY99_RS16640"
                     /old_locus_tag="GCM10010166_33380"
     CDS             complement(19645..20283)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013285276.1"
                     /locus_tag="IEY99_RS16640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_33380"
                     /product="response regulator transcription factor"
                     /protein_id="WP_189204168.1"
                     /transl_table=11
                     /translation="MRVLLVAHDASVAEPLVGGLAHYGIVAEHVTTGAAALAARPADLV
                     LLDAGLPDLDGIEVRRRTGDAKLIMLTAPGDDAQRILGTALGADDYLPKPVSVRDVVDR
                     MRAVGGRPAAPPVRACGPLTIDVGARQVRVHKIPVSLSPKEFDLLALLAEAPGAVVDRH
                     RILQTVWGPEFAGPGRTLDFHVASLRRKLGDPAWIENRRGVGFRLTPPA"
ORIGIN
        1 caccgtggtc ttcacccgca acaccaccga cgcgctcaac ctgctcgccc atgtcctgcc
       61 cgagggcacc accgtggtga ccttcgacgc cgagcaccac gccaacctgc tgccgtggcg
      121 cgcgccggtg cgcctcggcg tgccccgctc ggccgcggag gcggtctcca cgctggacga
      181 ggcgctgcgc gcgctgcccg gccccgcgct ggtggcggtc accgcggcca gcaacgtgac
      241 cggggagctg tggccgatcg ccgagctggc cgagacggcg caccgccacg gcgcccggat
      301 cgccgtcgac gccgcgcagc tggccccgca cgggcccgtg gacatcaccg cgctgggcgc
      361 cgactacgtg gcgctgtccg ggcacaaggt ctacgccccg ttcggggcgg gcgtgctcgc
      421 cgggcgcgcc gactggctcg acgccgcacc gccctacctg gccggcggcg gcgcgaccgc
      481 ggcggtgtcg tccgacttca ccgtacggtg gcacgacggc ccggcccggc acgaggccgg
      541 cacgcccaac ctgctcgggg cggtggccct ggcgaccgcc tgccgggccc tggccgaggc
      601 cgacctcacc caggagcacc gcctcgtggc gcgcctgcgc gccggcatcg ccgccctgcc
      661 ccgcgtcgag gagctgcgcc tgttcggccc gcaggcaccc cgggtcggca tcgtgtcgtt
      721 cgcggtgctc ggccgcgacc acgacgagct gggcacgatc ctcggccgcg accatgcgat
      781 cggggtacgg accgggctgt tctgcgccca cccgctgacc caccgcctgc tgcgcgaggc
      841 caccgaccgc ctcgacccgg cggccgcccc gcccggtgcg gcgatccggg ccagcgcggg
      901 catcggcacc accgaggagc acatcgaccg cctgctggcc gtgctggccc agcacacctg
      961 accggccaac ccgaggtctt gctggattgc ggcaaggctc agcgccgtcg gcccgccagt
     1021 cgccgacgaa ctgatccacc tgagacgctg atcacgatga ggacgcccgc caggacgcac
     1081 acgaccgcgg cgagtaacgg cgccaggttg tacgcctccg ctgtcgggcc cacggcggtg
     1141 aaggcgtcac ccggcgtgag agagccgaaa tgccagaccg gtaacgcgat ggcgatgagt
     1201 cgtccctcca cccgatcgga gggaatcgcg ccacttccct gggtgtcgat ccgggcccga
     1261 gagtcacgag cgacggctcg attgtcgccc atgacgaagt agcgtccggc ggggacggtg
     1321 acgctgaagg gccggccttc ctgccggttg tcgccctcgg cgtacttttc cgcgatcggc
     1381 ttgtcgttca ccagcaactg gccttcgggg ttggcggcga cgcggtcgcc cggcaagccg
     1441 atgacgcgca tggcgtagat cgcgtcgggc ggatcacctt cccacgttcc accgcggaag
     1501 gtgatgacat cgccgcgctg gatgtcgctg gtggtgacct tctcctgtac agctcgctcg
     1561 tccggctcca gggaaccgct catcgccgtg cttcgtaccg tgtagacgtc gaaccgcaga
     1621 gccaggaaga ccgccgccgc aacgatgagg acgacgccgg ccaggccagc cgcggtgcga
     1681 cgtcgagcga accgcggtgc cttcgttgtg cttacggtgt cattcacgac ggatatcctc
     1741 tgccttgatc cggtagccga ccacgagcgc accgactgct atgcaaacga acacggagag
     1801 gccgatcgcc ggatacatgg aatcgagcgc accgttgtac cagccggcct gtcggccgtt
     1861 gactttcagc caggcgttgc cggccaggta gccgaccgcg gtcgcgagga ggatcccgcc
     1921 gaccaggggc acacccagct gaacaatctg aattacccgg acggtgcgcc gccggacacc
     1981 gaggacggcg agcgcgacga cttcgcgtcg tcgctccacc atgcggtcga ccgccgcgac
     2041 ggcgaaggca agtagacaga gcccgagtcc ggcgatgaca ccgaagctca ccgtgccacg
     2101 atgtacgcgg taggcctcca aggcatcgag gttgagctgc ttcacgtgca tgctcgcggt
     2161 gggagagatc cgctgaacgg ctgacttgaa ccgttcgaga tcggcgcctg acgctccgat
     2221 gacgaacgtc atactgaggt ctggcgacca gccgaacttg ggctgcggtg ccgccgagat
     2281 gacaccgttc tcgcccagcg gcgtgcggtc ggcctcggga atcgggagga acgcggccgg
     2341 ggtggtgtac gcgacctctt ggccggtttc gttgcggaac ttcacggtga cgcccgcggg
     2401 cacctcggag acggtgccgt tgagcgccgg atccccgaaa cggtagtcgg tgccctctcg
     2461 gcagtcgggc aagggctgcc cgaccatcgt ccggacgtcg tcgcagctcg ccatcaccat
     2521 tgtcattccg ataccccgca cgcgctgttc cggggtcgac aggtccggca cgtcttcgac
     2581 gatgctctgc tgcaggcgcc aggtggcgat cgacggagtg gcggcgatcg cccgccgctg
     2641 gtccgcagtg gcgacggtgc gggtgtcgat cactactgta cgtgcggtga ccgtcggtcc
     2701 agcagccagc gcggcgtcgc ggagcacgcc ggcgctgatg ccggcgatca gtaccagcag
     2761 gaccggtccg ctggtcaggc gcagcagcga gcctggatcg gcagcgagtc tggcgcccgc
     2821 tactcgaagg aacagtggat agcgctgccc tcgcaaggag tggcccagca gagggatcgc
     2881 gtaccgcagg gccatcatcg tgccgacgac gcaagcggcg atgccggcga ggatgaggta
     2941 ggcggtggtg tcgctgacgc cctgccgggc gtcggcggcc gactgggccg atatcagcgg
     3001 cggcagcagc aggccgaggc cgacgaccaa gggagcaagc atccagacgg tgagccggcg
     3061 tccggcggac gcgcgggcct gtagcggctt cttgacgctt tgccgcagtc ccagtgcgcc
     3121 cagaaaagcg gcaccggcgg cggctatcac aacgagcagg accgctgtcg gcagatctag
     3181 ccgggatacc tcggcatacc aggtgaaacc cagcaccttc gagtccgcga gctcccgatt
     3241 gatcgagttg aacgacagga cgccgagcac agcaccgccg acgcccgcga cggcagcctc
     3301 ggtggcagcc atccgaacgg tctgctttcg acgcacaccg agcagccgca gcgcggcata
     3361 ccgctgggcc cgcgtgcgcg ctgccagccg cccgcagatg accaagaaga cggagaccgg
     3421 gatgaacatg agcagcatca gctcatacga caccccgccg agttgctcgg cgacgctctg
     3481 gtcgggggtc gcattgccga acgagattcc ggcgctaccg ccggcaaggt cgtccggcac
     3541 gacaccgaca tacgcgtaca gctcgttcgg accgagcagc ccggacggcc cgatcgtgcc
     3601 caccaccgta cccggcatcc gctcggcgac cagtgggtcg gcccgcatga cctgcaacgc
     3661 tctgggcgag gcgaagatct cgccgggcgc cgggaaccgg ctgaggcccg gcggcggcgg
     3721 tgccgcctcc ttcaccttgg ccaggaagac ccgagtgaac cgctcgtcgt gccacgagtc
     3781 ggtgacgaac gtgaaaccga aggcggcgtt ctcctccatt gccgaattgg gtagacggtc
     3841 ggacgatcgc atcgcccggt cgtccagaac cgtcggcagc gccatggcag tggcgaccac
     3901 cagcgcgcca accccgaagc cgagaatcat caagatgagc cgggcgagtc ccgcccatcc
     3961 gccaccgcgc agcaaccgca gcgtcagtag ccaggtcacc aagactcctc gtccgtctta
     4021 ccatcgcgca tggtgacgac gcggtgcgcc cgggcggcca gggcattgtc gtgcgtcacc
     4081 aggacgaccg cggcgccgct accgttggcc agttcgatca gggcgttgaa cacgacggcg
     4141 ccgttctcgg tgtcgagcgc gcctgtcggc tcgtcggcga agagtacggc ggggcggtgc
     4201 gcgagcgccc gggccaccgc ggcacgctgc gcctgacccc cagagacaaa cgccggtcga
     4261 cgcccggcct gcccctgcag gccgagcgtc tccacaagct cggcgacccg tttccggcgg
     4321 tcccggcggc cgacaccgtt cagtgtcaac ggtagttcga tattctcccg cagcgtcagt
     4381 tcaggcacga ggtcggcgaa ctggaagacg aatccgaaat ggcgccggcg aacgtccgac
     4441 cgttcgtcgt cggacatccg gcacaggtcc cgcccgttga acagcacctc tccggaatcc
     4501 ggttggagga tacccgccag gcagtacaac atcgtcgact tcccggagcc gcttgggccg
     4561 accagagcca gcagttcccc cggtgacacg gtggcgctcg ctttcgcgag tgccaccgtg
     4621 tcaccgtatg acaacgaaag atcagctgcg gacagcaaag acgttcctag cttctatcgg
     4681 ttgagtcggc tgctgatgtc gcaggtgtcc gagccccagt cgtcggtgca gatctggtac
     4741 cagccgtacg aaacgaagtt tacgtcgttg gaagagaacg tacggctctc cgtgccacat
     4801 ccggaagcgc tgccgttccc gtcactgacc ttcgaactcc aggcgtatcc gagaatcttg
     4861 ccctgaccgt acacaccatt gccgtcagcc gcagtgtcac acaccgtgcc actcaccttc
     4921 attccaccac ggtaggtgcc gttgaaggtg taggaaccct tgaagcgcat cttgtcatcg
     4981 cccagatcga gcgttccact gccgtaggcg taggcggacg acccgatcgc gagcgcagcg
     5041 aggcttccca ggccgatggc agcgacgatg ttcttgctct tcgacacaaa aactcctgac
     5101 gaaaggacag acgggcgtcc atcgacgcgg ggcacatctg tcaatgttct cacccccgct
     5161 cgggggcgcc aggaaagctt gctgcggaaa gacctgcgga tcaacgccct gttggcggac
     5221 aatctcgcta tctcactggc ggcacccttg accgttcggg cggacgacct cggccgaaca
     5281 cacgccttta tagaccaatg tgtcgtaggg gcgagtgaag ggacccttcg agggaccact
     5341 gcctaaacag gaacagcacg agtaccagca ttccccggag cgccatttcg tgggttgcgg
     5401 ctcagctgaa ccgctcgccc cacaggcacc aactgctggc cgagctggcc ggtcacagtt
     5461 ggcggcaccc tgcccgggcc cgccccgcgt ccgggcccgg gcccgcctgc gtgccctccg
     5521 gccggcgccg ggcaaaggcc cccgcgccac gactgccagc gcggtctgcg ccggcacggc
     5581 ccccgccggc acggcgggtg agagccctag ccgtgaaccc ggcgagcgcg acgaccgcgg
     5641 gcaccaccac gtagctgccg ctgagcagga gtgtcagtcc ggtgagcgca gtgccggcga
     5701 tcgcggtcgc gcgcatcggg cccgccggca gcagccggac cgccgccagg ctgcccaggg
     5761 ccatgacggc ggccaggcat gccgaggtcg cccgcagaag gggatccagg ccgaccggcc
     5821 ggagcagcgt ggccgcgccg acgacggcga cccccgcgcc cagcgccacc agactgcggt
     5881 acggcgacga gatccggtgc ggcagcagcc gtcgcccggc gagcgccacc gccaggcggg
     5941 acgccccggc cacgtacgtg ttgatcgcgc cgaacgtcag gaccagggcc gcgaccgtgg
     6001 tcaccggtcc ggcggccgcg ccgatccgcg tggccagcat ggccgtgagc ggcaccggcg
     6061 aggacgccgc gccggagccg acgaccgtga ccgccacgcc cagatagacc atggtgatcg
     6121 ccgccagggt gaggccggtc gccgtcagca ggcgccgccc ggcgaactcc gccgagaggt
     6181 ggctggcggc ctcccagccc acgaaggcga agatcaggac accggccgcg ctgccgacgc
     6241 cgccgaggcc gtgcggcagg aagggctcga aacggccggc gcggaccgcg ggcaggctcg
     6301 cggcgaccgc ggcggtcagc accgcgagca ggatgccgac catcacgacc tgcatgcgac
     6361 cgctggtccg cagacccgcc gcgttggcgg cgaacgccga cgccagcagt ccgcaggcga
     6421 acaccgcggc gacccggccg tccccgccga acgcctgcgc cgcgtagacg ccacccgcga
     6481 gcgccccggc cagcgtgccg agcggcaccg cggcgaggaa ccaccatccg gcgatcgagt
     6541 acgcccagcg gcccatcgcc atcccggcga agtgcgccac cccgccgccg tccggatggc
     6601 gcagcccgag cagtgcgaac gtgaacgcga ccgggacgct gatgaggatc agcgccgccc
     6661 aggccagaac cgatccgggt cccgccgcct ccgcggccag gtgcggaagc accagcatgc
     6721 cgggtcccag cacaccaccg agcacggtcg ccgtcccctg ccacactccc aatcgatgcc
     6781 gtgtcatgcg acgacggtag gcaaccgttc gatccgagcc cccgcacgcc gaacgaatgg
     6841 tcgaaacccg atggcaaaat gggccggtgg acgaacttga cgcgcgaatc gtcggcctgc
     6901 tccagtcaga tgcccggctc tccaaccggg agctcgcccg gcagctcggc gtcgccccgt
     6961 cgacctgcct ggagcgggtc cggtcgctgg cccgccgcgg cgtgatcagg ggctatcacg
     7021 ccgacatcga cccggcggcg ctcaaccgcg gcgtacaggc gatgatctcg gtgcaggtcc
     7081 ggccgctgag ccgggccgtc atcgacacct tcaaggcatc ggcggcgcag atgcccgagg
     7141 tgctcagcgt cttcgtcctg gccggcggtg acgacttcct gctgcacgtc ggggtgcccg
     7201 atctcgacgc gatgcacgcc ttcctcctcg accggctcag caaacgccgc gaggtcaccg
     7261 gcttccgcac gtccgtcatc taccagcagg tcagcaaccc ggcgccgggc ctgctccccg
     7321 ggcccgcctg accgcggagg cgccgacgct cagacgcgta ccgggagctc cagggtctgg
     7381 ccccgctcca ccggccggat gcccgtcagg cccgcctcgc gcgcccggtc caggtacgtg
     7441 gagaccggca tcttctggac cttgtagtcg tcgttgtgga tcggcacggt cagcccgggc
     7501 cggatcagct cggtggtggc gacgccgtgc cggtcgtcca tggtcagcag catgccgagc
     7561 acccgggtgc ccccgaggtg gatgagcatg gcgtcgatcg ggccgcaccg ctgcgggatc
     7621 tcctgcagcc acgggccgtg cagggtgtcg cccgtgatgt acaggcgcag gcggcagcgg
     7681 ccctcggctt ccagctcgag caccgagccc atcaccgccg gcagcagcag gtcgaccggg
     7741 ccgggcccgt gcctgccggg tacggccgtg acgcgcagcc gctggccgcc gcgctcccac
     7801 tcgcaggtct cccaggtcgc cagccctcgg gcgtcgctga accgcttgcg ccgcaacctg
     7861 cgctgcgcct gcggggtggt gacgatcggc agcccggacg gcaggtcgcg gcgcgcggcc
     7921 cggtcgaagt ggtcgccgtg caggtgcgac agcagcacgg cgtccagcgc cgcgacgtcg
     7981 accacctcca ggaccgggtc gaggacgcgc ttggtccaca ggccgttgcc gaggtacacc
     8041 cggctgcccg ccggcccgaa ggccgggtcg gtcagcaggc tgaagccgcc caggcggagc
     8101 acggtggtcg cgttgcccac gaaggtcacg ctcgcgttca cggtcatccc gggcgcgtac
     8161 ccgcggacga ggcgttcatg cgggccccgg cgcggatcag ccgaggtcgt cgccggcgag
     8221 cgcgcgggtc acgtagtccg ccaggtcggt cgcgaccgtg cgacacacac cggtgcgccg
     8281 ctcccaggcg acgatgccgc gcgacgggtc cgcggggacg cagccgacca gctcgtcgcc
     8341 gtccgcgcca ccgcccccga acaggagcag agcgccgggc cgcagcgcaa ggttgtcgcg
     8401 cacgatgcgc tcgaccggcc acaccacggg caggccgcca cggccgcgca cgccgccggt
     8461 ctcgcacagc agctcggcga ggtcctccgg gagcgccgca ccgagccgct cccccgcggc
     8521 cgcgacgtcc tgcggggccg cggcaccggc gagcgtggcc gagggcagca ccgcgaggac
     8581 gacgtcacgc cacgagaccg cgagcatggt ggccatccta cgaggacggc cggtcccgga
     8641 cgaggaccgg cccgtttcca ccacatcgac gcacgtcatg caggatcggc cgggagcacg
     8701 gacgcgggcg gggcgaggaa ccggcagctt tcgatcacgt cgggtccccg ggtcgacagc
     8761 cgactccgga tgaagaggcg aggtcaggag ggcgggatgg ggatgtccgg ctcggcggcc
     8821 cgcgccgccc ggatgcgcac gcccagctcg tacagtcggc gggcgtcggt ctgggcgtat
     8881 tccagcgcgc gcgtggcgag ctgctcggcg gcacggctga ccgtctcggc gacctcgcgg
     8941 gccaccgcgt gcgccgcctc ggcctggtcg acctgcgcga cgagcctgag gttgccgggc
     9001 tcctcgcggt gcgcgtcgcg cagcacggtg agcagctccc aggccaggcg ctcgtcgcgg
     9061 tgggcggcct gctgggcatc ggccgccgag agggcggcca ggtcacggtt gacggcacgc
     9121 accgctatgt cgtcgcgcag cgcttcgtac tcggcgagga gctgacggcg ctcctccggc
     9181 gacatccccg aaagctcgga caccccagca agctagcacc gcggaccgca ggtttgtcca
     9241 ccgtcgaccc gaacgaggac gcagatgccg gtcgatgttc agcggtcggc ggcgacgtag
     9301 gcgcggaacg cctcgacggc gcgcccggtc agggcgcgac cgtggccgaa gacggcgtgg
     9361 tcgaagtcca gctcggcgag ccgggcgacg ctgcggcgct gcgcgtccag atccgccgag
     9421 accatcttcg gggcactgcc gatccggccc ccgcgccgcc cgcccgccgc gtcgccggcg
     9481 aagagcaccc ctcccgcgcg gtccagcagg tacgacatgt ggccgggggt gtgcccgggg
     9541 gtgtgcaggg cggtgaagcc cggcacgggc acggcgccgt cctcgctcac cacctcgtcg
     9601 accgtcgcgg gctccgcccg gcccatgacg aggccgacca gcttcaccac cgggtggcgc
     9661 gagaccgcct ggatctctcc ggtcacgtac ggcacgtcgt cgcggtgggc gacgacccgc
     9721 gccccggacc ggcggcgcac ctcggcgagg ccgccggtgt ggtcgggatg gtggtgggtg
     9781 agcagcacgg tggtgacgtc gccgatcgtg cggcggatgt cgtgcagggc ccgcccgatg
     9841 cgcgccgacc ggcccggcag tccggtgtcg acgagcacca cgccgtcgtc ggtgacgacg
     9901 aggtgcacgt ggacatagcc gatcccgacc tcgaagacgc cgtccaccac ttcacgcatg
     9961 gcgtgatgat gccatccccg gcgcaggggc ggggagggga tcagcgatga cgggtgacga
    10021 ccgaggcagc cagcgtggcc agggccgccc gcgcgtccgg ggtgagcggc gcgcggtcca
    10081 gggccgcggt ggccgcggcg gcgcgccgcc cgatcagctc ctcgatcccg tccctggcgc
    10141 cggtcgcctc gatgatcgcc cgcagctccc ccgcgcccgc ctcgtcgagg ccgggatcgc
    10201 cgaagagctc ccggatccgg gcgtgctggg cccggtcggc gcggtcgcgg gccagcgcca
    10261 gcatcgcggt gggcttgccc tcgcgcaggt cgtcgaggac cggcttgccg gtgacggcgg
    10321 ggtcgccgaa gacgccgagc acgtcgtcgc gcagctggaa ggcgtcgccg agcggatcgc
    10381 cgaaggcctg cagcgccgcc tgcagccgcg ggccggcccc ggccagtccg gcgccgatct
    10441 gcagcggccg ggtgacggtg tagcgggcgg ccttcatccg gatcacggtg agcgccccgg
    10501 cgaccgagcc gtggccgacg ccggacacga gatcgaggta ctgaccggcg atgacctccg
    10561 tgcgcatcgc cgtgaacatc cggtagccgc ggtggatcca ctcgacgggc agaccgcagt
    10621 cgtggaacat gtggtccgcc caggcggcgc agagatcgcc gcagagcagg gcggcgctct
    10681 ggccgtaccg gacggcctcg ccccgccagc ggtggcgggc gtgcaggtcg gcgaagtggc
    10741 ggtggacggt cggctggccg cggcgcagcg cgctgccgtc catgatgtcg tcgtggatga
    10801 gggcgaaggc gtggaacagc tccagcgccg cggcggccgc gacgatcgcc tggccgtcgg
    10861 gctgcccggc gccgcgccag ccccagtagc agaacatcgg gcgcaggcgc ttgccgtcgg
    10921 cgagcacgaa ccggcggacg gcgtcgagca ccccgcgggg tgtgccgtcc ggccagtgcg
    10981 ggcgctgccg gtccaggtac gcgacgagcg ccgcctcgca ccggcgggcc agcccggccg
    11041 cgtcggtctg cgcggccgtc ccgacggtca cgacctcagc cccgcgagct cgagcagcag
    11101 ccccttcacc tcggtggcgg cgaccgccgg gcgctgggcc gccgggtcgg agcagagcag
    11161 caccggcgcg tcggccgggt cggtgggcgg gcgcccgtgc gagccgcgga ccgcgcgggc
    11221 gccggcgtcc aggcccacca cgctcatcgt gtagcgcagg ccgagcttcc tgcgcagcag
    11281 ggcgagcgcg gcgcggcccc gggccgcggc cgggccggcc gggtcgaaga agagctcggc
    11341 ggggtcgtag cccggcttgc ggtggatctc gaccagccgc gcgaagtcgg gcgccgcggc
    11401 gtcgtcgagc cagtagtagt aggtgaacca ggagtcgggc tcggcgacga cgaccagctc
    11461 gcccgagcgt tcgtggtcga gcccgtgcgc ggcctgggcg ggccggtcca gcacctcggc
    11521 gacgccgggc aggccggcgc agagcttcgc caccgccggg acgtcgtcgg cggacgccac
    11581 gtagacgtgg gcgatctggt ggtcggccac ggcgaaggcc cgcgaggtcc agggatcgag
    11641 gtactccatc ccggcctggg tgtacacgtg cagcaacccc tcggcgcgca gcagccggtt
    11701 gacgtcgacg ggccgggaca cgtcggtgat gccgtactcg gacacgacgg cgacgaccgc
    11761 cccgcgccgg gcggcggcgt cgagcagcgg gccgagggtg gcgtccagct cggcggcggc
    11821 ccgggcggcc tgcggggccg acgggccgtg gcgttgcagg tcgtagtcga ggtgcggaac
    11881 gtagaccagg gtgaggtccg ggtcgtgcgc ggccatgatc cgctgcgccg cgccgcagat
    11941 ccaggccgag gaggcgatcc cggccttcgc gccccagtag ctgaacagcg ggaaggtgcc
    12001 gagctcggcg gtcagggtgt cgtgcagctg cggcgggtac gtgtagcagt ccgggtcctt
    12061 gcgcccgtcg gcgtggtaga tcggccgcgg ggtcaccgtc cagtcgaccg gggcgcccat
    12121 cgcgtaccac cagcagacgt tggcgacggt gtagccgggt acgagcgagc gggcggcgtc
    12181 ccacaccttc tcgccgcgga ccagggcgtg gtgctggcgc cagaggagca cctcgccgag
    12241 gtcgcggaag taccagccgt tgccgacgat gccgtgcccg ctgggcagcg tgccggtgag
    12301 gaacgtcgac tgcaccgtgc acgtcaccgc gggcagcacg gtgcccagcg gcgcctggaa
    12361 gccggcctcg gcgagccgcg tcaggcgggg catgtgccgc agcagccgcg gggtcaggcc
    12421 gacgacgtcg agcacgacca cgggcctcac gacggcaccc cctgggcggt cgcgagcccg
    12481 agcgcggcca gccgggcgcg ggcgaagaag agctccgcgg cgatgccgga cgccagctcc
    12541 gcggggcccg ccggccgcga cgccggcggc agcacatgcc aggtgtacgt ctccacgtcc
    12601 aggtggtcgc agccggccgt gtcaccgccc agcagctccc gcagggcggc ggcgagcacg
    12661 tcgacggtgg agcgcagcgg cgggaccggc gcctggtgca gcggcacgtg gtagtgcacc
    12721 cgccacggct gcgcgtcgcc gccgggcgtg gccagcgcct cgtccaggtc gtcggcggcc
    12781 agcccggccg agccccgggt ctggtgcagg aagcgcggtt cggcgtactc gccgagcacg
    12841 gcggcgtcgc ggcgcgggtc ggcgctggcc agcgccgccg acagctgggt cttgaccacc
    12901 ggcagccccg ctcggcgcag ccgccgcagg gcctgcgccg gctcctccca cgcgcaggcg
    12961 aggtgggcga ggtcgaggca gacaccgagc accgacgtgt cggcctcgcc gagcagggcg
    13021 accgcctccg cggtcgtctc gacgacgcag ccgggctccg gctcgaaggc cacccgtacc
    13081 ggccgcggca gctcgtgcag gccgcgggcc aggtcgtcga gggcccgccg gcaggcgccc
    13141 gcccggtccg cgtcccaggg ttcccgccag gccagcggca gcgtggagat cgacccgcgc
    13201 gcggcgtcac ccggcagcag gtcggtcagg atccgggcca ggtcgagggt gtacgcgagc
    13261 cgctgcggcc tggtccagtc gggctggtag acggcgtgct tgaccaccgg ctcctggaac
    13321 gcctggtacg ggaacccgtt gagggtcacc acctccagcc cccgggcgtc cagggcgcgg
    13381 cgcaggcgcc ggcggtcggc gggcgccccg gcgagcccgg cggcgaccgg cgcggccagc
    13441 cacaggccga gcccgagcac gtcggcgccg aggcgctcgc ggatcggcac ggcgtaagtg
    13501 tcgagctgcg ccaggatccc gtcgaggctt tcggcggcat ggacgttggt gcagtacgac
    13561 aggtgcacgg tcgtcccgtc ggggtggtac aggcgcatca gctgcctccc cgggcgatcg
    13621 agctgccggc gtacgccccc gatccgtcgg gcggcgagag gtccaggcgc cccgaccgcc
    13681 cgtagaactc ggcggggttg cgccacagca cccggtcgac ctcgtcggcg gtgaacccgg
    13741 cctcgagcat cgcccgcccg gtggcgacgg tcagcagcgg gtccgagtgg ccccagtcgg
    13801 cggcggagtt gaccagcacg cgctcggtgc cgtactgcgt caggatctcc accatccgcg
    13861 acggcgacat cttggtctcg gggtagatgg agaagcccag ccagcagccg gagtcgcgga
    13921 ccatggcgac cgtgacctcg ttgaggtggt cgacggcgac catgccgggg tcgatgccgc
    13981 aggcggcgac gacctccagg ctgcggcggg tgcccgccgc cttgtcccgg tgcggggtgt
    14041 gcaccagcgc gggcagctcg tagcgcaccg ccagctccag ctgggcggcg aaggcctcgt
    14101 cctcggccgg cgtcatcgcg tcgtacccga tctcaccgac cgcgaccacc ccgtccttgt
    14161 cgaggtagcg cggcagcagg tcgagcactc ccttgcagcg cgggtcgttg gcctccttgg
    14221 ggttgagcgc gagggtggcg tggtggcgga tgccgaactg cgaggcccgg tacggctccc
    14281 acccgagcag cgagtcgaag tagtcggcga aggagcccgg gttggtgcgc ggctgcccga
    14341 gccagaacgc gggctcgacc accgcccgta tcccgtggtc cgccatcctg cggtagtcgt
    14401 cggtggtccg agaggtcatg tggatgtgcg ggtcgaagac gcgcatcagt cctccttgcg
    14461 cagcaggtgg cggttgagca gcgcgacggc gtcggcgctc agccggcgtc cggcggccgc
    14521 gcgctcggtg gccagggcgg cgagcatggc gaccagcgcc gcgtcggtgc ggtcgtcgag
    14581 gcggtcgaca ccgctgagcg cgatgcccat gaacacgcac ttcaccacgc cctggcgcca
    14641 ggtggcggcg tcgaggtgcg ccgcgtacgg cccgagcgcg gccgccacga gccgcgggtc
    14701 gttgctgcgc agcgcgtcct cggccagcgg caccccggcg gcgccgatgt ccagcagggg
    14761 cagggcgtgc agcacggcga ggcgctcggc ggagtcgccg taccagtaga gctcggcgac
    14821 ccggtcggcg gcggcgacgg cgagcagcag caggacccgt ccggcctgcc cggcggtcca
    14881 gccgggacgc tccggcagcg gctggcggcc gagcttgcga ccggcccggg cgaacagcgg
    14941 cccggcgctg tccgggtcgg cccggacccg ggcctccgcc tcgtcgaacc aggccttgcc
    15001 gggtacggcg gccaccaccg cccgcagctc ctcgagggtc accgcggcac ctcccgctcg
    15061 gcggcccgca gaaaggcgag cgactcccgg gcgaccgtgg gtgccgcgtg ggagtgccgg
    15121 ggcagctcga cggcgaccag gccgcggtat ccgccgtcga tcagggcccg cagcacgggt
    15181 gggaagtcga tctccccggt gccgagctcc aggtgctcgt gcacgccccg ccgcatgtcg
    15241 tcgatctgca cgttgaccag gtacggcacc gccgccgcga cgcagtccgg cacgggctcg
    15301 ggctcgacgc agcggcagtg cccgatgtcg agggtgagcc cgaacgcggc gggggcgccc
    15361 agctcgccgc gcagccggtg ccagccggcg aggtccgcca cgagcatccc cggctcgggt
    15421 tcgaagccga ccggcacccc gagcgcggcg gccacgccgg tgatctcggc gcatccgtcg
    15481 accaggcggc gccaggcggt gcgctcgtcc acctcggcgg gacgggtccc ggcccagaac
    15541 gacaccgcct cggcgccgag gtcggcggcg acggagacgg cccggcgcag gaagtccagc
    15601 cgcagcttgc ggtcgtcgtg cagcagggtg ggcgcgtgct tgcgccacgg atcgagcagg
    15661 taacgggcgc cggtctcgac gaccacgccg aggtcgcggt cgcggagccg gtcggcgacc
    15721 gcggcgaccc ggcgggcgag cccgggggcg aacgggtcca ggtggccgtg gtcgagggtg
    15781 agcgcgacac cgcggtagcc gaggccggcg atcacctcga tcgcctcggt gaggcggtgg
    15841 ccggcgaagc cgttggtgcc gtagccgtac cgcagggcgc tcatgtgggc gacacccggc
    15901 gggcgagccg gcggccgagc ggcgcggcgg ccgcgaccgc gagaccggcg agcgtgcggc
    15961 cggccccggc ggtgagcgcg ccctgcagcg cgggcagcgc cgtgatgccc gccccgacgg
    16021 cggcacgcac ccgggcggcc cgcggatcgg cgatcaccgc ggcctgcgcc cggcctacgt
    16081 cggcggcgta ccggccggcg agcagcgcgg ccgccggtcc gccccgggcg gccgtcacgc
    16141 cggccaccgc cgtggtggtc gccagggcgg cggcgggcag cgacggcgtg ggacatcccg
    16201 cgacctcgtg ccgggacatg acggtgacca cgtacgtgtg cacggcgatc gtcgcggcgg
    16261 tcggcagcgc ccggaccgca gctccggcgc tggcgcccag cagcacgtcg agtgcccggc
    16321 aggcggccat cccggccggt ccggcggcgg tgtccttgag gcgcaggtcg taggcccaca
    16381 ccgcggcggc cagcgggacc gcggcggtga gcgcccggga accgccggcg cggccggcga
    16441 tcgccagccc ggcggcggtg agcccggcgg cgacgcccag cgcgaccggc gggctcaccc
    16501 ggcccgacgg gatggggcgc tccgggcgct gcacggcgtc gagatcgcgg tcggcccagt
    16561 cgttcgcggc catcccggcc cagtagaggc agaccgacgc ggccgcgagc ccggcgctgc
    16621 gggcgccgag ggtgcccgcg gcggcggcgc ccgccaccac gtccccgggt acggacagcg
    16681 cggcgggcgc gcggaccagc tcggcgaggg cccgcagcgg cgccttcatc ggcccagccc
    16741 ggcggcgaac ccggcgagcg cgtcccactg cgcggccagc gcgcaggggc cgtcgccgag
    16801 cgggtccttg aagaagaagc ccagctcggt caggggtccg tgccgcccgg cccggtgcgc
    16861 cgccgcggtg agccgggcca ggtcgagcac gagcggcgcg gcgagcgcgg agtcgcagcc
    16921 gtgccaggtg aactccatgc gcatccgggt gccgaggaag ccggcgaagg tgatcaggtc
    16981 ccaggcggtc ttgaagtcgc cgagctcggc gacgtggtcg atgcggctgg tgccctccgg
    17041 gcggtagccg agcgcgtcgc cgagcacccg ctgcttgctg gcgaccttgg cggcgttcgc
    17101 ggccgggtcg gcgaggttgg cgccgtcgcc gccgccgagc aggttgacgc cggaccagct
    17161 ggtcacccgc agatggcgcc gggcgaacat cggcgcgagc acggacttga ccagcgtctc
    17221 gccggtcttg ccgtcgtggc cggcgtaggg cacggcggcc gcggcggcga gctcggccag
    17281 cgcgggcagg cgcgcgccgg tcgacggggt gaagtccacg aaggagcagc ccgccacgaa
    17341 ggacgcgtac gcggccagcg agctcggcgg cagcacggcc tccggaccgg cgagcgcctc
    17401 gcgcagcgcc gcgagcgagg cgtgcgcgcc gtggcgggcc acggccggct cggtggcggc
    17461 gacgttgacg accacgaccc gctcgagggc gtggcgccgg cggaagtcgc gcaggtcggc
    17521 ggcgatcgcc ccggcgatcc acgcctgggt tccgccgtcg ggcagcgggc gcagatcctg
    17581 ctcggcccgg ccgagctcgt cggcgagggc ggcgacgagg cggccgggca gcacgccggc
    17641 ggcggccagg tcctcggcct tcttcgtcac cggcagggtc accacgtcgt ggccgccgaa
    17701 caccaggtcc gcccagccgg ggaggggggc gccgcgcagc tccggcagct cggtgacgca
    17761 gcccgtgggc ccggccaggc gggcccgcag ggcgagggct ccggtcagcg cggtgaccgc
    17821 gacggagccg cgcgcgccga tcaaccagac tccggtacgc atgcggcatc ccctccgaag
    17881 acacggaccc ggctcgcagt aacgcgatgt gtcttgtgcg ttacgtgagg cgacgctaac
    17941 gcagtcccgg cgccaaagga aaccctcaat atcgagaaac ttctctatcg gtcgggagaa
    18001 ctttcttgtc ctccgtacga aagtgggcac gccccgtagg gtggcggcat gattgtcgag
    18061 gcggacccct ggtacgggct catcgtggag cttctggacc ggtcccatct gtggcgcccc
    18121 gaggacatgg gcggcgtgct ggacggggcg gccgagcgcc tcggcctgcg gatgacggtg
    18181 tacgtcgccg acgccgagca gcgctcgctg cggccgctcg ccgtgccggg acgctccgcc
    18241 cccgccccgc tgcccatcga cgcgcatgcc gccggacggg ccttctccct ggtcgagtcg
    18301 gtggtcgcgg acggccggcg gtgggtgccg atggtcaacg gcaccgaccg gatcggggtc
    18361 gtcgaggtgg cgacgccgga cgggaccgcg ccggacgagc ggctggcccg gccgtgcgag
    18421 gtcgtctccg gcctggtcgg gcacctgatc accaccacgc tcccccgagg cgaccacctg
    18481 caccgggccc gccggtcgag gccgatgacc gccggcgccg aactgctctg gcagctgctg
    18541 ccgccgctga cggtcagcat cgccgacttc gccgtcgccg cggtgctgga gccgacgtac
    18601 gacgtcggcg gcgacgcctt cgactacacg gtggacggcc gccggccgca gttcgtcgtc
    18661 ctggacgccg cgggacacgg cctgaaggcc ggcctggccg cggcggtcgc gctcgcctgc
    18721 ctccgcgccg cgcggcgctc cggcggcgac ctgccggacc aggcccgggc cgccgacgag
    18781 gagctgctgc ggcagttccc ggacgcccgg ttcgtcacgg cggtcctcgc cgagctggac
    18841 ctcgacaccg gcgtgctgcg ctacctcaac gccggtcacc cgccgccgct cgtgctgcgg
    18901 gacggcgcgg tcgtcgagac gctggccgag gggcgccggc tgccgctcgg catcgcggac
    18961 ccgcgcgcca catgtgccga gatcaccctg cggcccggcg accgcctgct gctctacacc
    19021 gacggtgtca ccgaggcacg ggacgccgcc ggcgtgccct tcgggcagaa ccgcctcgcc
    19081 gacagcctgg aacggcacgc cgccgagggg ttgccgatcc ccgagaccct gcgccggctc
    19141 tcgcacaccg tcctcgccca ccagagcgga cccccggccg acgacctcac cctgctcctg
    19201 gtggaatggt cggcgggcgc ggcacggcga accgtgccgc ccacctcacg agggggcgaa
    19261 caggcagcat gaatcccgac atcctcagcg tgaccttcca cgacccggcg gacggggtca
    19321 gggtgctgtc ggtggccggg gagatcgacc acgacagcgt cgaggtgctg cgcgacgcgg
    19381 tggaacgggc cctggccgac ggccgggacc gcctcgtgtg cgacctctcg gccgtgccgt
    19441 tctgcgactc gggcggcctg agcctgttcg tcgagaccca ccggcgcgcc acggcccggg
    19501 gcggctggct gcggcttgcg ggcccgcagg accaggtccg gttcgtgctc gacgtcgcca
    19561 acctcgaccg ttatctgggc gtgcacccca ccctggacga ggcactctcc gcggccgggc
    19621 aatagcggca ggatccgcgc cggctcaggc cgggggcgtc aggcggaagc cgaccccgcg
    19681 ccggttctcg atccaggccg ggtcgccgag cttgcggcgc aggctggcca cgtggaagtc
    19741 gagcgtacgg cccggccccg cgaactccgg tccccacacc gtctgcagta tccggtggcg
    19801 gtcgaccacg gcgcccgggg cctcggccag caacgccagc aggtcgaact ccttggggct
    19861 cagcgacacg ggtatcttgt ggacccgtac ctggcgggcg ccgacatcga tggtgagcgg
    19921 tccacaggcg cgtaccggcg gcgcggcggg gcggccgccg accgcgcgca tccggtccac
    19981 gacgtcgcgg acgctgaccg gcttgggcag gtagtcgtcg gcgccgaggg ccgtgccgag
    20041 gatgcgttgc gcgtcgtcgc cgggcgccgt gagcatgatg agcttggcgt cgccggtacg
    20101 ccggcggacc tcgatgccgt cgaggtcggg cagccccgcg tcgagcagca ccaggtcggc
    20161 ggggcgcgcg gcgagcgcgg cggcgccggt cgtgacgtgc tcggcgacga tgccgtagtg
    20221 ggccaggccg ccgaccaaag gctcggcgac ggacgcgtcg tgtgccacca gcagaaccct
    20281 catggccgct gatacggacg gcacgcccct cgcggttcag cgcggggcgc ccggaaagat
    20341 cgcggccggg cgccgagcac gagccgcagg gcgtacgacc acgccgccgg cccggcgccg
    20401 ggccagcggc gaccggccta cgagatctcg taggccaggt tggggcgcag ccaccgctcg
    20461 acctcgtcga cggtgaggcc gcgtcgggcc gcgtagtcct cgatctggtc cctgcccagc
    20521 cggcccacgg tgaagtagcg ggactgcggg tgggcgaaga tcaggccgct gaccgccgcc
    20581 gccggggtca tcgcgtacga ctcggtgagg ccgatgccca gcgactgcgc gccgagcagc
    20641 tcgaagaggt ccttcttctc gctgtggtcg gggctggccg ggtagccgag cgccgggcgg
    20701 atgccgcgga agcgctcggc gtgcaggtcc tcgatcaccg ggtcggcgtc cggctcgaac
    20761 cagtcgcggc gggcctgcag gtgcaggtgc tcggcgaagg cctcggcgag gcggtcggcg
    20821 agcgccttga ccatgatggc gcggtagtcg tcgtgctcgg cctcgtagcg ggccgccagc
    20881 tcctcggcgc cgtggatcgc gacggcgaag ccgcccaggt ggtcctgctg cgtcccggcc
    20941 ggcgcgatgt agtcggcgag gcagcggttg gcgcggccct ccggcttggc ggtctgctgg
    21001 cgcagcatcg ggaagcgcac gccgttgtcc agcacgatgt cgtcgccgtc ggcgtgggcg
    21061 ggccagaagg c
//
