LOCUS       NZ_BMQY01000002        22631 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Couchioplanes caeruleus subsp. azureus strain JCM 3246 sequence02,
            whole genome shotgun sequence.
ACCESSION   NZ_BMQY01000002
VERSION     NZ_BMQY01000002.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Couchioplanes caeruleus subsp. azureus
  ORGANISM  Couchioplanes caeruleus subsp. azureus
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Couchioplanes.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 909631)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 64X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014648355.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 03:32:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,801
            CDSs (total)                      :: 6,731
            Genes (coding)                    :: 6,630
            CDSs (with protein)               :: 6,630
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 20 of 101
            Pseudo Genes (incomplete)         :: 93 of 101
            Pseudo Genes (internal stop)      :: 0 of 101
            Pseudo Genes (multiple problems)  :: 12 of 101
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:23:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 133651
            Orig. end                         :: 156282
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMQY01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22631
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22631
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22631
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12631](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12631)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    5..15
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            62..979
                     /locus_tag="IEY99_RS07835"
                     /old_locus_tag="GCM10010166_15720"
     CDS             62..979
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020510278.1"
                     /locus_tag="IEY99_RS07835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_15720"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_189200938.1"
                     /transl_table=11
                     /translation="MDTHLLDVFRTVAHLGSITTAARRLGFTQSAVSRQIGALEAEVGG
                     KVFDRLPRGVALTETGRALLPYAEEILDRLAAARRAVDDLRRLDAGRLRVGAFPTAVAA
                     LVPRALAAFRAAYPSVGLSLLEGLTPALLDRLAAGEADVAVVSTAPSAPIDPARFTLHH
                     LVDERLLVAVARGHRLADRTTVRLADLAADPFVVGSATAEQGLLRAGLPHGFRPKIDLV
                     AADWTGKLGCVAAGLGVALVPALAARSAPPDVALLHLHADDESVRRIHAATPAGRTSPA
                     AVTHFLAELRKEARQFAGAPLRGD"
     gene            complement(976..2028)
                     /locus_tag="IEY99_RS07840"
                     /old_locus_tag="GCM10010166_15730"
     CDS             complement(976..2028)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY99_RS07840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010166_15730"
                     /product="hypothetical protein"
                     /protein_id="WP_189200940.1"
                     /transl_table=11
                     /translation="MTSLLEERYRRVLRLLPADYRHAWEEDMVDTFLQAAYDADPEDPE
                     GVEISSPGKAEVASIVALALRLRLGGAGAAPRRFAWGEATRLVALAGLLAPTVLALSDA
                     LFMAWVAGHMDDFIGPEGIPEGSWLADRWLALWALTGLLWLPAYLSVLFGHRRAAHVLA
                     VIALLPVLISGAERLSRDEFTATEAYELLLVVLPVLALAAFHRDAPPVRCRPWLIALPA
                     GVALVLAAHLPLRLAGDWDAWFLPLVDRPALACAVLIGATVMQAVPGSRIPSWPLALAL
                     LVAAALVLRLMTTLGYLGYDSPNHIAMATIGAVQCAALLAAGGYLTRVAVRGMRRLPAP
                     ARPATDARHG"
     gene            complement(2025..2372)
                     /locus_tag="IEY99_RS07845"
                     /old_locus_tag="GCM10010166_15740"
     CDS             complement(2025..2372)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013735217.1"
                     /locus_tag="IEY99_RS07845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_15740"
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_229798307.1"
                     /transl_table=11
                     /translation="MTARPMTEPAFFILTALVDTPRHGYGIVSEVNQLSEGRVALKIGT
                     LYGVLDRLVADGLVELDREEPHQGRLRRYYRLTDRGIAALSEEVARQAANAEAAGRRLA
                     AYRPATAGGLG"
     gene            2432..2728
                     /locus_tag="IEY99_RS07850"
                     /old_locus_tag="GCM10010166_15750"
     CDS             2432..2728
                     /EC_number="1.14.-.-"
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015925.5"
                     /locus_tag="IEY99_RS07850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_15750"
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="WP_189200942.1"
                     /transl_table=11
                     /translation="MILEHALLPVRPGQEAAFEAAFRQARSIIAGMPGFARLTLSRCVE
                     RPGTYLLLVEWDSLEAHTIGFRGSAQYQRWRELLHHFYEPFPTVEHYEQVLTA"
     gene            complement(2776..3573)
                     /locus_tag="IEY99_RS07855"
                     /old_locus_tag="GCM10010166_15760"
     CDS             complement(2776..3573)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014690813.1"
                     /locus_tag="IEY99_RS07855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_15760"
                     /product="ElyC/SanA/YdcF family protein"
                     /protein_id="WP_189200944.1"
                     /transl_table=11
                     /translation="MAGTDVVANLNTLVDFCALRDVGTLSRAAVDEAAGGRVDVAILFG
                     GSILAGGDLFARAVKDDVAARFMVAGGQGHSTDVLRAAMRRHTDCDDVADRTEAALFDR
                     YLRERYGIQIDLLEHESTNCGSNVRNALALLAARDVPHRRILIIQDGSMQRRMDAGFRR
                     YAPGVRLVNFAAHRTPVELVGDELGFRSPPAGMWPVDRYVSLLMGEIPRLTDDREGYGP
                     AGRGFIAHVGVPAEVTRAYSALRAHGVGTPRAADPRWASTEGP"
     gene            complement(3761..4168)
                     /locus_tag="IEY99_RS07860"
                     /old_locus_tag="GCM10010166_15770"
     CDS             complement(3761..4168)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024092.5"
                     /locus_tag="IEY99_RS07860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_15770"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_189200946.1"
                     /transl_table=11
                     /translation="MALTHREIFERYVYAGAISRNPEAVAAMFTEDGVFEAPLVPGGHP
                     LPSRLVGRDAIRSGLAASYEYWADLGAVNTELSTLVLHETADTDVFIAETDTVLEQAGG
                     QHTTLSLVQIFRLRDGQIARLRDYFAVPPSH"
     misc_feature    complement(4139..4152)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 12.0"
                     /tool="antismash"
     gene            4801..5574
                     /locus_tag="IEY99_RS07865"
     CDS             4801..5574
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY99_RS07865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_189200948.1"
                     /transl_table=11
                     /translation="MADILVRPAPPAGVARLPLPDLNVALQVRTLLDLNAALRLPAHLD
                     VNAALHLPALLDLDAALHLPALLDLNAALHLPALLDVNVAVHLAAAPRLTVGLHLPALP
                     GRGTPPRMPAPLPAWGSAGHTVPPAVPPAAGPAAAAAASAAAPATPRRAGGVVRCRGGT
                     GCGPHATAPVADAGTRGDRTRPGSAAGRTPRPELPSRPTPHGTSERAAGGAAGGAPAVG
                     ALPSSWRPGPAAASVPPGEATAARGRTVVYAGPPS"
     gene            5732..6340
                     /locus_tag="IEY99_RS07870"
                     /old_locus_tag="GCM10010166_15790"
     CDS             5732..6340
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014443465.1"
                     /locus_tag="IEY99_RS07870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_15790"
                     /product="response regulator transcription factor"
                     /protein_id="WP_189200950.1"
                     /transl_table=11
                     /translation="MIRILLAEPMNLLRGALAATLSQEQDLDVVADLGRLDEVLPMARV
                     VSPDVAVINTDLLAAPEPGVVDRMRLELPHCGILLLAGADAPARLSRTLDAGVRGFVDK
                     QAGPHELAYGIRRAARGERVMDARLAVAVLAAPRNPLSARERDVLVVAASGAPSQEIAA
                     KLHLSTGTVRNYISAILRKTGARNRLEAVRIAREAGWLD"
     gene            complement(6260..8083)
                     /locus_tag="IEY99_RS07875"
                     /old_locus_tag="GCM10010166_15800"
     CDS             complement(6260..8083)
                     /EC_number="7.-.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015621710.1"
                     /locus_tag="IEY99_RS07875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_15800"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_189200952.1"
                     /transl_table=11
                     /translation="MRFLLAFLRRRPRVLVRLAGWSGLEALPAVLSGQAVARAVDRGFL
                     AGDPAAGLGWLGLLAAAVLLGAAGTRRTFRCLADLAEPLRDELVAHVVAGTLRRAASAG
                     GGADRSAVARLTHQVEIVRDTFAGLIVTMRGFLFAVAGALLGLASLAPVVALLVAAPLL
                     AGLAMFAATVPRAAARQRAYVRAGEDLAEHAGRAFAGLRDIAACGAGRRMAAEISVPVD
                     AQAAAERAVARTTAARGISLAAGGWLPLAVVLTAAPWLVHHGLTAGAVLGSLTYLLHGV
                     QPALTMLVGGLGGGGVRLAVTLDRILHGGDSAPAARGTSALAACGDSAPAACGASARGG
                     PAARPGGADVLLRGVTFAYGRRAEPVVSGLDLDVRDGDHLAIIGPSGIGKSTLLSLLAG
                     TLQPQQGDVRLGGVRTDRLDVRTLARHRVLIPQEAYVFTGTLLDNLRYLRPGAAVPDID
                     RAAEAIGLDAVVRRLGGYDARITPDALSAGERQLVALVRAYLSPARLVLLDEATCHLDA
                     AGEARAERAFAARPGALVVVAHRVSSAWRASRILLLDGSSATLGTDGSLRRTSPLYRDL
                     AGRWHSVEPAGLPGDADRLQPVAGAGLAQDR"
     gene            complement(8080..9780)
                     /locus_tag="IEY99_RS07880"
                     /old_locus_tag="GCM10010166_15810"
     CDS             complement(8080..9780)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007461899.1"
                     /locus_tag="IEY99_RS07880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_15810"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_189200953.1"
                     /transl_table=11
                     /translation="MSVVEGDRLLVRSVRHGGPWAAGLAVAALTAAVADLLLPAALGAA
                     VDAVLAPDARPGRWLAVAVGLVALIAAAEISTDLAAGMSGARATARLRHTLAGHVLALD
                     PRAARRFPPGDLVSRLAGQVPEAGGAAAAVVLAGAAVVPPLGSLVALALIDPWLGATFV
                     GGLAVLVALMRTYVTDAAEATTRYQRTQSDIAARLTEALAGARTIGAAGTVEREIARVL
                     RPLPDLGRHGGRTWDMLGTAAARGAVVAPLAQLAVVAVAGLALTAGRLTPGALLAALQY
                     ATLGAGLGGVVGVLGRIARARAGSGRIAEVLAAPAHRHGDAGLPPGDGRLELRAVTVRH
                     PAGGDRPVLDGIDLEVPGGATVAVVGRSGAGKSTLAAVAGRLLDPDEGDVRLDGVPLRR
                     LRPEALRRAVGYAFARPVLVGDTVGAAIGLGPDRRTPELVRADARAARVDTVVERLPAG
                     YDTPLREAPLSGGEAQRLGVARALRAERLLVLDDATSSLDTVTEHEVYQALLGTRDRRT
                     RLVVTHRAGTAARADLVVWLDRGRVRACAPHDVLRPDPEYRALFPAAGR"
     gene            complement(9877..9996)
                     /locus_tag="IEY99_RS07885"
                     /old_locus_tag="GCM10010166_15820"
     CDS             complement(9877..9996)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013734295.1"
                     /locus_tag="IEY99_RS07885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_15820"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_189200955.1"
                     /transl_table=11
                     /translation="MALMDLQGMELTPEAAYGGGSRASLLLCGDSSLSVTTCD"
     CDS_motif       complement(9931..9996)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MALMDLQGMELTPEAAYGGGSR"
                     /locus_tag="IEY99_RS07885_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9877..9930)
                     /prepeptide="core"
                     /locus_tag="IEY99_RS07885_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="10.70"
                     /molecular_weight="1576.8"
                     /monoisotopic_mass="1575.8"
                     /core_sequence="ASLLLCGDSSLSVTTCD"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MALMDLQGMELTPEAAYGGGSR"
                     /leader_location="[9930:9996](-)"
                     /alternative_weights="1594.8"
                     /alternative_weights="1612.8"
                     /alternative_weights="1630.8"
                     /alternative_weights="1648.8"
     gene            complement(10001..12631)
                     /gene="lanKC"
                     /locus_tag="IEY99_RS07890"
                     /old_locus_tag="GCM10010166_15830"
     CDS             complement(10001..12631)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013734294.1"
                     /locus_tag="IEY99_RS07890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_15830"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_189200957.1"
                     /sec_met_domain="micKC (E-value: 3.9e-249, bitscore: 824.6,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 1.1e-08, bitscore: 30.3,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.8e-10, bitscore:
                     35.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRQYERFCVVDPLFYDSLSTRRPVAGLFAAARRAVPPGWRREAL
                     DDWLVYAPTDGSLPDQGWKIHVSACLHNADRVLDVVFGYCVAHAVAFKFVHGPAALLLR
                     NAKYARRGTSGKFVTVYPRDEAELELVCKELGDLLRGEPGPYVLSDLRLGSGPLHVRYG
                     GFAARYCVVDGVVEPAIADPSGRLVPDRRDPVFRMPGWVSLPAFLAPDLAARNATTTAD
                     LPYRIDRVIHFSNGGGLYAATDTRSGDRVVLKEARPHAGLDATGADAVWRLDQEHAALQ
                     RLAGLAVPRVHDRFRLGEHEFLALEYIDGTPLNKLLVERYPLVDPTADPQRYRAYAAWA
                     TDIHRQVERTVEAIHERGLVYGDLHLFNVLVRTGTPEGDTIALVDFEVAGPVDGYRRPG
                     LRNQGFAAPREVGGRDVDRYALACLKLALFLPLTAMLRLAPGKAHHFAEVIRERFGVPE
                     DYLADAVATIASASSASSGSVTRPRGGWRQFPSGTAGWPVLRGQLAEAIVGSATPQRDD
                     RLFPGDVEQFRSGGLNLAYGAAGVLYSLHLTGAGRHPGFEDWLVRRAVDPPAGARLGFY
                     DGLHGVAYALHRLGRRQEALDIVDRCLRERWDELGSDLMSGLAGIGLNLAYLADATGEA
                     ALDAGARRATDLLSERLRGAGDTPATSGVRLRPAGLTHGWTGPALLFLRMYERTGDGTL
                     LDRAATAIHRDLDRCVVRDDGALEVDEGWRTMPYLARGSVGIGTVADQVLAHRDDDRLA
                     GASAAIGLAARSPFYAQSGLFAGRAGIIRYLAGRDRDGEPVRAQIRDLAWHAVPFRGGL
                     AFPGEQLLRLSMDLATGSAGVLLALGAALHHEPVDLPFLSPAAGTSRASLRPEGKKIHT
                     EHGKG"
     gene            complement(12791..14635)
                     /locus_tag="IEY99_RS07895"
                     /old_locus_tag="GCM10010166_15840"
     CDS             complement(12791..14635)
                     /EC_number="2.7.7.65"
                     /GO_function="GO:0009975 - cyclase activity [Evidence IEA]"
                     /GO_process="GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR00254.1"
                     /locus_tag="IEY99_RS07895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_15840"
                     /product="GGDEF domain-containing protein"
                     /protein_id="WP_189200959.1"
                     /transl_table=11
                     /translation="MTSVDRPGQAAARTTSAWSRAWIAWSAAALLPIAGYYTVPATDAG
                     AVLQTVLYCLVSGSTAVALAVGIRRHRPRPGSIWWLFVAGQVMYTSGDVTYYIASQHDA
                     SYPVAANVLYLAQYFFVAAALVQLTRRRSPQRNTAALVDTTILAVGAAVLWWVFLIHPT
                     VTAPDIDTVDRVAATAYPVMDLCVLTVAIRLMLSGGVRQPAYHLLLAFLALNLFADTAY
                     GLLTLTGSFADGGWTDALWLLGYVALGAAGLHPSMRHLADPAEPRSGATPYRVVLLGFA
                     TAMAPAVLVVQNLRGAARSDLVVVGASAVLFLLVLVRMAGLIAAQRRLAITDALTGLYT
                     RRFLSEQLRVESERAARSGGPLALLLLDVDHFKRINDTYGHPAGDQVLVEVARRLRATC
                     RAGDVVARFGGEEFAVLTTATDPQHLTAVAERIRTQINAVPVLVDGHTPVAVTVSIGGT
                     TAEPPQTPDELVNAADTALYAAKRGGRDRVVVTTGLADLAPATAPEAHPGELPELDRSI
                     QDWAAVVGEAARRRADAVPVPASAIAGLCAAWAVMRAPGPGKPAMPAGEARAELRRCRG
                     VQFPPHLVDEFLVLEANGVIGTLDPAPVAADEPVTVAA"
     misc_feature    complement(14631..14648)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.37"
                     /tool="antismash"
     misc_feature    14720..14736
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.12"
                     /tool="antismash"
     gene            14844..17591
                     /locus_tag="IEY99_RS34860"
                     /old_locus_tag="GCM10010166_15850"
     CDS             14844..17591
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020510445.1"
                     /locus_tag="IEY99_RS34860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_15850"
                     /product="AAA family ATPase"
                     /protein_id="WP_373293324.1"
                     /transl_table=11
                     /translation="MFGRAPLLAAVEARLASGGGVALHGPEGIGKTAVLDAVAAAAAAR
                     DELVVRVRPAAADRLLPYAGIADLVAQLPETAVAALPPAHRAALAMLRQGAAPRTGAPA
                     LARRLVLPGLLAHCARARPVLLVLDDVQWLDAESAELVGFAMRRRPGPRVRVVAAQRLP
                     DDAGRHRAARLCPAPVADLLVPPLDADDLSALLEARGLPCRAAARLHEASGGNPFLALA
                     LGAVAPGPPWRPAPLPEAARDLLRRRVAALPPPVAATLLVAALATEPTLTVLVRAGHED
                     ADRDLRVAAAAGVVRTDGETIRFTPPALADVLTEDAGAARRAGVHDALANTALDETIAV
                     RHRALRSGRPDADVARDLLEAAERAVRRNAARTAAELYLLAADRCPRSLAAQRFDWLVA
                     AARTATATGVPAVAGRAAEAVLAAADAPAAHRVQARIVLLDLAGQALAEMDETFAGALN
                     EAGTDVALLAPVKLRLAWAAMLGGAVRSAGVCAAEAARAARAAGDPTTEAMALSSLAQV
                     QRLRGEPQWTGTLRRALSLPAPQVPGLLHLSPRYLAARFAMMDDRLDEARAELLTLLAV
                     AEHDRAGEALVEVLRSLSEVATRAGRCREALRYAHRAVTAAQQAGLSPGPTWYTAAVAE
                     LAGGSLAAASGYARRGVRASEQEGDSLYLRRSLHALGQAQLRAGDTRGGVATLRRLSEL
                     ADGAADPMIVRWQGDLAGGLAALGEHDEAAATLAAARAAADRLGAAPGLHGYLDRATAV
                     VLSERGQADSAVLLCATAAQHFADLRQPLEQAHALLVQGGAERRRRRYAAARAALGAAL
                     ALFLAAEAKPWTEQARHAFARTEGTAAPPSDLGLTSTEARIAGLVRDGASNREIAGRLF
                     LSVKTVEATLTRVYRKLGVRSRTQLSQRLPATRVFPDSVTTVDA"
     gene            17679..19904
                     /locus_tag="IEY99_RS07905"
                     /old_locus_tag="GCM10010166_15860"
     CDS             17679..19904
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009072865.1"
                     /locus_tag="IEY99_RS07905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_15860"
                     /product="M4 family metallopeptidase"
                     /protein_id="WP_229798309.1"
                     /transl_table=11
                     /translation="MGRRKLISASAALATGAALTLAAAPASAQPQRAPGPPSGPALAAA
                     AADRLVHSAGTASLLRRSDGDTLERTGVVQGTRGLQYVTYARTFRGLPVVGGDVVVTTD
                     AAGTVKDTAVAQTAPIAVGTTATVTAAQAAAAARGRLASVDRATAPRLEVLAWGTPTLV
                     YEAVVEGRTAQHKPSNLHVFVDAHTGKVVEQVDYVREGTGTGYYYGNVTISTSGSGSSW
                     SMTDPTRPGLKCGGQNGSAYTGTDDVWGNGSGTNLETACVDALWGAQREADMLSAWFNR
                     NGINGNGNNPPIRVGLNDVNAYWNGSYTNFGHNQANTRQATPIDVVAHEMGHAIFQYTP
                     GGAGGGNENGGINEATGDIFGALTEAYANSPLDPPDYQVGEEVDLVGDGPIRYMYNPSL
                     AGDPNCWSTSIPSTEVHAAAGPLNHWFYLVAEGSAPTNGQPASPTCNSSSVTGISIRKA
                     GEIYYNALQAKTSTWKYANVRTASLTAAKNLYPNSCTEFNTVKAAWNAISVPAQPGEAT
                     CTGTPGNDFSVSASPASGSVAAGAAATTTIATATTSGAAQTVALSASGLPGGATATFNP
                     ASVTSGSSATLTISTSASTPSGSYPITVTGTGSATHSVTYTLTVTGGPGGSCTASNGTD
                     VSIPDAGAAVTSTITVSGCGRNASATSTVAVNIVHTYRGDLVIDLVAPDGTAYRLKNSS
                     ISDGADNVNATYTANLSAEAGNGAWKLQVRDVYSADTGHLDTWTLTL"
     gene            complement(19964..20254)
                     /locus_tag="IEY99_RS34070"
                     /old_locus_tag="GCM10010166_15870"
     CDS             complement(19964..20254)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017760.5"
                     /locus_tag="IEY99_RS34070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_15870"
                     /product="MFS transporter"
                     /protein_id="WP_229798311.1"
                     /transl_table=11
                     /translation="MDADGFWPEPHLELDPDDHDGPYLLHRLGERVLVVRPDRDGENPG
                     RFVEAYVVPSRDEHLRQHTGRLTGADQAVEQRAQALAEGPPQVSHLLSGRR"
     gene            complement(<20278..20367)
                     /locus_tag="IEY99_RS35240"
                     /pseudo=""
     CDS             complement(<20278..20367)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017760.5"
                     /locus_tag="IEY99_RS35240"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTVPAPAAVPAAPSAWAPLRIAAFRSLWLA"
     gene            20525..20839
                     /locus_tag="IEY99_RS07920"
                     /old_locus_tag="GCM10010166_15890"
     CDS             20525..20839
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR00377.1"
                     /locus_tag="IEY99_RS07920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010166_15890"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_189200963.1"
                     /transl_table=11
                     /translation="MDTSVDGRLDVVLRGELDFTNASQVAKVVKEAIVGGRPRAVRVRL
                     AEVTFLDSSGIGLLVRAMKAAGEVGADFRVEEPTDKVLDQLRMSGLLEAFGLPQPPPET
                     "
     misc_feature    complement(21569..21583)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
     misc_feature    21640..21655
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.76"
                     /tool="antismash"
     misc_feature    21661..21674
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 17.74"
                     /tool="antismash"
     misc_feature    21662..21675
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.61"
                     /tool="antismash"
ORIGIN
        1 cgggagccat gtcaccagcg aatctctggc atgcctgaca tgcccgtcta gcatatcagg
       61 catggacacc catctgctcg acgtcttccg gacggtggcg cacctcgggt cgatcaccac
      121 cgcggcgcgg cgcctcggct tcacccagtc ggccgtctcc cggcagatcg gcgcgctcga
      181 ggccgaggtc gggggcaagg tgttcgaccg gctgccgcgc ggggtcgcgc tgaccgagac
      241 cgggcgggcg ctgcttccgt acgcggagga gatcctcgac cggctcgcgg cggcccgtcg
      301 cgccgtcgac gacctccgcc gcctcgacgc cggccggctg cgggtgggcg ccttcccgac
      361 cgcggtcgcc gccctggtgc cccgggcgct ggccgcgttc cgcgccgcgt acccctcggt
      421 cggcctgtcc ctgctcgaag gcctgacccc cgccctgctc gaccgcctcg ccgcgggcga
      481 ggccgacgtc gccgtggtga gcaccgcgcc gtccgcgccg atcgaccccg cgcggttcac
      541 gctgcaccac ctggtcgacg agcggctcct cgtcgccgtg gcgcgcgggc accggctggc
      601 ggaccggacg acggtacgcc tggccgacct ggccgcggac cccttcgtcg tcggctcggc
      661 caccgcggaa cagggcctgc tccgagccgg tctgccccac ggcttccggc cgaagatcga
      721 cctggtcgcc gccgactgga ccggcaagct cggctgcgtg gccgcgggcc tcggcgtggc
      781 attggtgccg gctctcgcgg cgcgcagcgc cccacccgac gtcgccctgc tccacctgca
      841 cgccgacgac gagtccgtac gccggatcca cgccgccacg ccggccgggc gcaccagccc
      901 cgctgccgtg acccacttcc tggccgagct caggaaggag gcgcggcagt tcgccggcgc
      961 gcccctccgg ggcgactagc cgtggcgggc gtcggtcgcg ggccgggccg gcgccggcag
     1021 gcggcgcatg ccgcgaacgg ccacccgggt caggtagccg cccgcggcca gcagggcggc
     1081 gcactgcacg gcgccgatcg tcgccatcgc gatgtggttc ggggagtcgt agccgaggta
     1141 gcccagcgtc gtcatcaggc gaaggaccag ggccgccgcg accagcaggg cgagcgccag
     1201 cggccagctc gggatgcgcg accccgggac cgcctgcatg acggtcgcgc cgatcagcac
     1261 cgcgcatgcc agggcgggcc ggtccaccag gggcaggaac cacgcgtccc agtcaccggc
     1321 gagccgcagg ggcagatggg cggcgaggac gagcgcgacg ccggcgggaa gggcgatcag
     1381 ccacggccgg caccggaccg gcggggcgtc ccggtgaaag gcggcgaggg cgagtaccgg
     1441 caggacgacg agcaggagct cataggcctc ggtggccgtg aactcgtcgc gggacagccg
     1501 ctcggcgccg gagatcagta ccgggagcag ggcgatcacc gccagcacgt gcgccgcgcg
     1561 ccggtgaccg aacaggaccg acagatacgc cgggagccac agcagcccgg tcagcgccca
     1621 gagagccagc cagcggtcgg cgagccagct gccctccggg atgccctcgg gaccgatgaa
     1681 atcgtccatg tgcccggcca cccatgccat gaacagcgcg tcggagagcg ccaggacggt
     1741 gggcgccagc aggccggcga gggcgaccag gcgggtcgcc tcgccccagg cgaagcgccg
     1801 cggggcggca ccggcgccgc cgaggcgcaa ccgcagcgcg agcgccacga tgctggccac
     1861 ctcggccttg cccgggctgc tgatctccac gccctccggg tcctccggat cggcgtcgta
     1921 cgccgcctgc aggaaggtgt cgaccatgtc ctcctcccag gcgtgccggt agtccgccgg
     1981 aagcaggcgc agcacccggc ggtagcgctc ctcgagcaga ctggtcatcc caggcctccc
     2041 gcggtcgcgg gccggtaggc ggccagccgc cggccggcgg cctcggcgtt ggcggcctgc
     2101 cgggcgacct cctcgctcag cgcggcgatg ccccggtcgg tgagccggta gtagcggcgc
     2161 agccgcccct ggtgcggctc ctcccggtcc agctcgacca gtccgtcggc gaccaaccgg
     2221 tcgaggacgc cgtacagcgt gccgatcttc agcgcgaccc ggccctcgga gagctggttc
     2281 acctcgctga cgatgccgta cccgtggcgg ggcgtgtcga ccagcgcggt gaggatgaag
     2341 aacgccggct cggtcatggg gcgtgcggtc atgggcccaa tataatgcaa ggcaagatat
     2401 cgtgcatcgg tccgtctgag atcatctccc gatgatcctc gagcatgcgc tgctgccggt
     2461 gaggcccgga caggaggccg cgttcgaggc ggccttccgg caggccagga gcatcatcgc
     2521 cggcatgccc ggcttcgctc gcctgacctt gtcccggtgc gtggagcggc cgggcacgta
     2581 cctgctgctg gtggagtggg actcgctgga ggcccacacg atcggcttcc gcggctcggc
     2641 gcagtaccag cgatggcggg agctgctgca tcacttctac gagccgttcc cgacggtgga
     2701 acactacgag caggtcctca ccgcctgacg ggctccggac tgctggtccg ggtcgcttgc
     2761 gaaacaggac cggacctagg gaccttccgt ggacgcccac cgcggatcgg cggcgcgcgg
     2821 cgtgcccact ccgtgcgccc gcagcgccga gtaggcccgc gtgacctcgg ccggcacgcc
     2881 cacgtgcgcg atgaagccac ggcccgccgg cccgtagccc tcccggtcgt cggtgagccg
     2941 gggaatctcg cccatcagca gggagacgta ccggtccacc ggccacatgc cggcgggcgg
     3001 cgaccggaac ccgagctcgt cgccgaccag ctcgacgggt gtccggtggg cggcgaagtt
     3061 caccagccgt acgcccgggg cgtaccggcg gaatccggcg tccatgcgcc gctgcatcga
     3121 cccgtcctgg atgatcagga tccgccggtg cgggacgtcc cgggcggcga gcagggccag
     3181 cgcgttgcgg acgttgctgc cgcagttcgt cgactcgtgc tccagaaggt cgatctggat
     3241 gccgtaccgt tcgcgcaggt agcggtcgaa gagggcggcc tccgtccggt ccgccacgtc
     3301 atcgcagtcc gtgtggcgcc gcatcgcggc gcgcaggacg tcggtggagt ggccctggcc
     3361 gccggcgacc atgaagcggg cggccacgtc gtccttgacg gcccgggcga acaggtcgcc
     3421 gccggcgagg atgctgccgc cgaagaggat ggcgacgtcc acccggccac cggccgcctc
     3481 gtcgaccgcg gcacggctca gcgtgccgac gtcgcgcagg gcgcagaagt cgacgagggt
     3541 gttcaggttc gcgacgacat cggttccggc cacggatccg agggtagccg tgcccgggcg
     3601 tcacgcagcg gcgttcgggg cgctcccggc cgggtcgggt gccgggcccg gcggccggcc
     3661 cccgccaccg ggacgaggac cggccgccgc ggccgggtcg ggtgccgggc ccggcggccg
     3721 gccaccgccg cggcggtgga gaccggccgc cgcccgggga tcagtgcgag ggcggcacgg
     3781 cgaagtagtc gcggagcctg gcgatctgcc cgtcacgcag gcggaagatc tgcaccagcg
     3841 acagagtcgt gtgctgtccg ccggcctgct ccaggacggt gtcggtctcg gcgatgaaca
     3901 cgtcggtgtc cgccgtttcg tgcaggacga gagtggacag ttcggtgttc accgcgccca
     3961 ggtcggccca gtactcgtag gaggcggcga gtccggaccg gatcgcgtcc cggcccacca
     4021 ggcgagaagg cagcggatga ccgccgggaa ccaggggcgc ttcgaacacc ccgtcctcgg
     4081 tgaacatcgc ggcgaccgct tccgggttgc gggagatcgc gccggcgtac acgtaccgtt
     4141 cgaagatttc tctgtgagtg agtgccactc tccagcatag ccggtgcgcc ttggtcgact
     4201 cgcgaccgtc ctcgcgcgac ggtagcctcg gccgaggagg tgagggtcgt gcgccgacat
     4261 gtcgccgtac cggcggtcgc tgcccttctc cgtctgcttc tgctcgccgg ggcggttgtc
     4321 gcggcgtacc tcgtgttcgg tctgctggat cgtccggccc gcgccgacct gggcatccgt
     4381 gacgcggctg cccgtcccgc cggtgaggac agagcccgga ctccggtgat tcatcgcccg
     4441 gtggtcaccg caacgccgtt gcggccggtc gtcgagcggt cggaacccgc gaccgagccg
     4501 tcccggccgg gcaccaggcg cgccgatccc gcggccgagc caccccgccg agccaccgag
     4561 ccgccgcccc gggcagccga aaagccgcgc cggaccgcgg aggaaccgcg gcggaccggg
     4621 gaacagtcac gcccggcttc ggaaaatcca cgctggtcgt cggaaaggcc gcgccggggc
     4681 gcggagaagt cccgccgaga tgcgggaaag ccgcgcgggg ccatggcaga gccgcgccgg
     4741 gcggcgggtg cggtccggga ccgggcacgc acggtacctc gtccggggaa ggtgcggacg
     4801 gtggccgaca tcctggtgcg cccggcgccg ccggccgggg tggctcggct gccgctgccc
     4861 gacctaaatg tcgcgcttca ggtgcgcacg ctgctcgacc tcaacgccgc cctgcgcctg
     4921 cccgcgcatc tcgatgtgaa cgccgctctg cacctgccgg cactgctcga cctcgacgcc
     4981 gccctgcacc tgcccgcgct gctcgacctc aacgccgccc tgcacctgcc ggcactgctc
     5041 gatgtgaacg tcgctgtgca cctggcggcg gcgcctcgac tgaccgtcgg gttgcacctg
     5101 ccggcgctgc cgggtcgcgg cacgccaccc cgcatgcccg caccgctccc ggcatgggga
     5161 tccgcggggc ataccgtgcc gcccgccgtt cccccggccg ccgggccggc cgcggccgcc
     5221 gcggcctcgg cggccgcgcc ggcaacgccg cgcagggccg gtggcgtggt gcggtgccgc
     5281 ggtgggaccg ggtgcgggcc acacgccacg gcaccggtcg cggatgccgg aacccgcggg
     5341 gaccggaccc ggcccgggtc ggcggcgggc cggacgccgc ggccggagct gccgtcgcgg
     5401 cccaccccgc acggcacgag cgagcgggcg gccggtggag ccgccggcgg cgcaccggcc
     5461 gtcggtgcgc tgccgtcgtc gtggcggccc ggaccggcgg cggcatccgt cccgccgggc
     5521 gaggcgaccg ccgcccgggg acgcaccgtc gtctacgcag gacctcccag ctgagcgggc
     5581 ctcccctcga gggacagcca gcaggccgtc accggcgtcg ccgctgaggg ccgtccgccg
     5641 ccgccccgcg tgatccgggc acccgagagg tgtccgtcgc cgggcgccgg cgtcccaccg
     5701 ccacgctctc atcctggcct gggaggccac cgtgatccgc atactgctcg ccgaacccat
     5761 gaaccttctc cgcggcgccc tcgccgccac cctctcgcaa gaacaggacc tggacgtggt
     5821 cgccgacctc gggcggctcg acgaggtgct cccgatggcg cgcgtcgtgt cacccgacgt
     5881 cgccgtgatc aacaccgatc tgctcgccgc cccggagccg ggcgtggtcg atcggatgcg
     5941 cctggagctg ccgcactgcg ggatcctcct gctggccggt gccgacgcgc ccgcccggct
     6001 gagccggacc ctggacgccg gggtacgcgg cttcgtcgac aagcaggccg ggccgcacga
     6061 gctcgcgtac ggcatccggc gggcggcccg cggcgagcgc gtgatggacg cgcgcctcgc
     6121 ggtcgccgtg ctggccgcgc cgcgcaaccc gttgtcggcg cgcgagcgcg acgtgctcgt
     6181 cgtggccgcg tccggcgcac cctcgcagga gatcgccgcc aagctgcacc tgagcaccgg
     6241 gacggtgcgc aactacatct cagcgatcct gcgcaagacc ggcgcccgca accggctgga
     6301 ggcggtccgc atcgcccggg aggccggctg gctcgactga gtgccaacgg ccggccaggt
     6361 cgcggtagag cggtgacgtg cggcgcagcg agccgtcggt gccgagcgtc gcggacgagc
     6421 cgtccagcag caggatccgg gacgcccgcc acgccgagct gacccggtgg gcgacgacga
     6481 ccagcgcgcc gggccgggcg gcgaacgccc gctcggcgcg ggcctcaccg gccgcgtcca
     6541 ggtggcaggt ggcctcgtcg agcaggacca gccgcgccgg cgacaggtac gcgcggacca
     6601 gggccacgag ctggcgttcg cccgcggaca gcgcgtccgg ggtgatgcgc gcgtcgtagc
     6661 cgcccagccg ccggaccacc gcgtcgagac cgatcgcctc ggccgcccgg tcgatgtcgg
     6721 gcacggcggc gccgggacgc aggtagcgca ggttgtcgag cagcgtgccg gtgaacacgt
     6781 acgcctcctg cgggatgagc acgcggtggc gggcgagcgt gcggacgtcc agccggtccg
     6841 tgcgcacgcc gcccaggcgc acgtcgccct gctgcggttg cagcgtgccc gcgagcaggc
     6901 tcaggagggt ggacttgccg atgccgctgg gcccgatgat cgccaggtgg tcgccgtcgc
     6961 ggacgtccag gtcgaggccg gagacgacgg gctcggcgcg ccggccgtag gcgaaggtga
     7021 cgccgcgcag cagcacgtcc gcgccgccgg gccgcgccgc cgggccgccg cgcgcggagg
     7081 cgccacacgc ggccggcgcg gagtcgccgc acgcggccag tgcggaggtg ccgcgcgcgg
     7141 ccggcgcgga gtcgccgccg tgcaggatgc ggtcgagggt caccgccagg cgtacgccac
     7201 cgccgcccag gccgccgacg agcatggtga gcgccggctg caccccgtgc agcaggtagg
     7261 tgagcgagcc caggaccgcc ccggccgtca gcccgtggtg caccagccac ggcgccgccg
     7321 tcaggacgac cgccagcggc agccagccgc ccgcggccag gctgatcccg cgcgccgcgg
     7381 tcgtccgggc caccgcccgt tccgcggcgg cttgcgcgtc gaccgggacg gagatctcgg
     7441 cggccatccg gcgcccggct ccacaggcgg cgatgtcgcg cagcccggcg aacgcgcggc
     7501 cggcgtgctc ggccagatcc tcgccggcgc gcacgtacgc gcgctgccgg gcggccgccc
     7561 gcggcaccgt cgcggcgaac atggcgagcc ccgccagcag cggcgccgcc acgagcagcg
     7621 ccaccaccgg cgccagggac gccagtccga gcagcgcccc cgcgacggcg aacaggaacc
     7681 cgcgcatggt cacgatcagg ccggcgaacg tgtcccggac gatctccacc tggtgggtga
     7741 gccgggccac cgccgaccgg tccgctcccc caccggcgct cgccgcccgg cgcagcgtgc
     7801 cggcgaccac gtgcgccacc agctcgtcgc gcagcggttc ggccaggtcg gcgaggcagc
     7861 ggaaggtgcg ccgggtgccg gccgcgccca gcaggaccgc cgcggcgagc aggcccagcc
     7921 agccgagacc ggcggccggg tcgccggcca ggaagccgcg gtcgaccgcg cgggcgacgg
     7981 cctgtccgga caggacggcg ggcagcgcct cgagcccgga ccagccggcc agccggacca
     8041 gcacgcgggg acggcggcgc aggaacgcca gcaggaacct catcgcccgg ccgccgggaa
     8101 gagcgcccgg tattccgggt cgggccgcag cacgtcgtgc ggcgcgcagg cgcggacccg
     8161 cccgcggtcc agccagacga cgagatcggc ccgcgcggcg gtgccggccc ggtgggtgac
     8221 caccagccgg gtacggcggt cgcgggtgcc caggagcgcc tggtacacct cgtgctccgt
     8281 gaccgtgtcc aggctggagg tggcgtcgtc gagcacgagc agccgctcgg cacgcagcgc
     8341 ccgggccacg ccgagccgtt gcgcctcgcc gccggacaac ggggcctcgc gcagcggggt
     8401 gtcgtagccg gcgggcagcc gctcgaccac cgtgtcgacc cgcgcggcgc gggcgtcggc
     8461 gcgcaccagc tccggggtgc ggcggtccgg gccgagcccg atggcggcac cgaccgtgtc
     8521 gccgacgagc accggacggg cgaaggcgta cccgacggcc cggcgcaggg cctccgggcg
     8581 cagccggcgc agcggcacgc cgtcgagccg cacgtcgccc tcgtccgggt cgagcagccg
     8641 gccggccacg gcggccaggg tcgacttgcc ggcgccggag cggccgacca ccgccacggt
     8701 cgcgccgccc ggcacctcga ggtcgatccc gtcgagcacg ggccggtcgc cgcccgcggg
     8761 gtggcgcacg gtcaccgcgc gcagctccag ccggccgtcc cccggaggca gaccggcgtc
     8821 gccgtggcgg tgcgcgggcg cggcgaggac ctcggcgatc cgcccgctgc ccgcccgggc
     8881 ccgggcgatg cgtcccagca cgccgaccac gccgcccagg cccgcgccga gggtggcgta
     8941 ctgcagggcg gccagcagcg cacccggcgt gagccggccg gcggtgagcg ccaggccggc
     9001 cacggcgacg acggcgagct gcgccagcgg ggccaccacc gcgccgcgcg ccgcggccgt
     9061 ccccagcatg tcccaggtgc ggccgccgtg ccggcccagg tccggcaggg gccgcaggac
     9121 ccgcgcgatc tcccgctcca cggtgccggc cgcgccgatg gtccgggcgc cggcgagcgc
     9181 ctccgtcagc cgggccgcga tgtcgctctg ggtgcgctgg tagcgggtgg tcgcctcggc
     9241 cgcgtcggtg acgtacgtcc gcatcagcgc gacgagcacc gccagcccgc ccacgaacgt
     9301 cgcgccgagc cacgggtcga tcagggcgag ggcgaccagg ctgcccagtg gcgggacgac
     9361 ggcggcgccg gcgaggacca cggccgccgc ggcgcctccc gcctcgggga cctggccggc
     9421 gagccggctg acgaggtcgc cgggcgggaa ccggcgcgcc gcccggggat cgagcgcgag
     9481 gacgtgaccg gcgagcgtgt gccgcagccg ggcggtggcc cgcgcaccgc tcatcccggc
     9541 ggcgaggtcg gtggagatct cggcggcggc gatcagggcc acgagtccga cggcgacggc
     9601 cagccagcgt cccgggcggg cgtccggtgc cagcaccgcg tcgacggcgg cgcccagcgc
     9661 ggccggcagg agcagatccg cgacggcggc cgtcagggcc gccaccgcca gcccggccgc
     9721 ccacgggccg ccgtgccgga ccgagcggac gagcagccga tcgccctcca cgacggacat
     9781 ggcacctcct gaccgctggg tctgcacggt ggggccccga accggagcaa ggggcagtcc
     9841 ggttcggggc ggttccggtg taccggctgg tgctcgtcag tcgcaggtcg tcacactgag
     9901 cgagctgtcg ccgcagagca gcaggctggc ccggcttcca ccgccgtacg cggcctcggg
     9961 ggtcagttcc atcccctgca ggtccataag tgccatctcg ttaccccttt ccgtgctcgg
    10021 tgtggatctt ctttccctcc ggccggaggg aagctcggga agtgcccgct gccgggctca
    10081 ggaacggcag gtcgacgggc tcgtggtgca gtgcggcgcc gagggcgagc aggacgccgg
    10141 cggatcccgt cgccaggtcc atcgacagcc gcagcaactg ctcgccggga aatgccagcc
    10201 cgccccggaa gggcaccgcg tgccaggcga ggtcgcggat ctgggcccgt accggctcgc
    10261 cgtcgcggtc gcgcccggcc aggtaccgga tgatgccggc ccggcccgcg aagagcccgg
    10321 actgcgcgta gaacggcgac cgcgcggcga ggccgatcgc ggcgctcgcc ccggcgaggc
    10381 ggtcgtcgtc gcggtgggcc agcacctggt cggcgaccgt gccgatgccg acgctgcccc
    10441 gggccaggta cggcatggtc cgccagccct cgtcgacctc cagcgcgccg tcgtcgcgca
    10501 ccacgcagcg gtcgaggtcc cggtggatcg ccgtggcggc gcggtccagc agcgtgccgt
    10561 cgccggtccg ctcgtacatc cgcaggaaca gcagcgcggg accggtccag ccgtgggtga
    10621 gccccgcggg gcgcaggcgg acgccgctgg tcgcgggcgt gtcacccgcg ccgcggagcc
    10681 gttcggacag caggtcggtc gctctccggg ccccggcgtc gagcgcggcc tcaccggtgg
    10741 cgtccgccag gtacgccagg ttgagcccga tgccggcgag cccgctcatc aggtcggagc
    10801 cgagctcgtc ccacctctcg cgcaggcagc ggtcgacgat gtcgagcgcc tcctgccgcc
    10861 ggcccagccg gtgcagggcg tacgcgacgc cgtgcagccc gtcgtagaag cccagccgcg
    10921 ctccggcggg cgggtcgacc gcccgccgga cgagccagtc ctcgaagccg gggtgccggc
    10981 cggcgcccgt gaggtgcagg ctgtacagca cgccggcggc gccgtaggcg aggttgagcc
    11041 ctcccgagcg gaactgctcg acgtcgcccg ggaagagccg gtcgtcgcgc tgcggcgtgg
    11101 cactgcccac gatggcctcg gcgagttgcc cgcgcagcac cggccagccg gcggtgccgg
    11161 acgggaactg ccgccacccg ccgcgcggcc gggtcaccga ccccgacgac gccgacgacg
    11221 ccgacgcgat cgtggcgacg gcgtcggcca ggtagtcctc gggtacgccg aaccgctccc
    11281 ggatcacctc ggcgaagtgg tgggccttgc cgggtgccag ccgcagcatg gcggtgagcg
    11341 gcaggaacag cgccagtttc aggcaggcca gcgcgtaccg gtcgacgtcg cgcccgccga
    11401 cctcgcgggg cgccgcgaag ccctggttgc gcagcccggg ccggcggtag ccgtcgaccg
    11461 ggccggcgac ctcgaagtcg accagcgcga tcgtgtcacc ctccggggtg ccggtacgca
    11521 ccagcacgtt gaacaggtgc aggtcgccgt agacgaggcc acgctcgtgg atcgcctcga
    11581 cggtccgctc cacctgccgg tggatgtccg tcgcccaggc ggcgtacgcg cggtaccgct
    11641 gcgggtcggc cgtcgggtcg acgagcggat agcgctcgac cagcagcttg ttcaggggcg
    11701 tgccgtcgat gtactccagc gccaggaact cgtgctcgcc cagccggaac cggtcgtgca
    11761 cccgcggcac ggcgaggccg gcgagccgct ggagcgcggc gtgctcctgg tcgaggcgcc
    11821 acaccgcgtc cgcgccggtg gcgtcgagcc ccgcgtgcgg ccgggcctcc ttgagcacca
    11881 cccggtcgcc ggagcgggtg tcggtggcgg cgtacaggcc gccgccgttg gagaagtgga
    11941 tcacccggtc gatgcggtac ggcagatcgg cggtggtcgt ggcattgcgg gcggcgagat
    12001 ccggggccag gaacgccggc agcgagaccc acccgggcat ccggaagacc gggtcgcgcc
    12061 ggtccgggac gagccggccg gacgggtccg cgatggcggg ctcgacgacg ccgtccacga
    12121 cgcagtagcg ggcggcgaag cctccgtagc gcacgtgcag cgggccggag ccgaggcgca
    12181 ggtcgctcag gacgtacggg ccgggctcgc cgcgcagcag gtcgccgagc tccttgcaca
    12241 ccagctcgag ttcggcctcg tcgcgggggt acaccgtgac gaacttgccg ctcgtgccgc
    12301 gccgggcgta tttggcgttg cgcagcagca gggcggccgg gccgtgcacg aacttgaacg
    12361 ccacggcgtg ggccacgcag tagccgaaca ccacgtccag tacccggtcg gcgttgtgca
    12421 ggcaggccga cacgtggatc ttccagccct ggtccgggag gctgccgtcg gtcggcgcgt
    12481 acacgagcca gtcgtcgagg gcctcgcgcc gccagccggg cgggaccgct cgccgggccg
    12541 cggcgaagag ccccgcaacc ggccgccggg tgctcaggga gtcgtagaag agcggatcca
    12601 ccacacagaa ccgctcgtac tgcctgtcca cggcccgctc ctctcccgct tcctggttgc
    12661 ttgccaccag tcttcgggca ggaggggtcg cgccccagtg cgcaccgtca ccgggtgacg
    12721 gtgcgcggag tcagaacgga ttgctgaccg cggtcatgtt tgcaccgcgg cgcggcaggc
    12781 cggagcggtc ctacgcggcg accgtgacgg gctcgtccgc ggcgacgggg gccgggtcga
    12841 gggtgccgat cacgccgttg gcctcgagca cgaggaactc gtccacgagg tgcgggggga
    12901 actgcacgcc gcggcaccgg cgcagctcgg cgcgggcctc gccggccggc atcgccggct
    12961 tgcccgggcc gggcgcgcgc atgacggccc acgcggcgca gagcccggcg atcgcgctgg
    13021 ccgggaccgg taccgcgtcg gcacggcggc gtgcggcctc gcccaccacc gcggcccagt
    13081 cctggatgga acggtcgagc tcgggcagct ccccggggtg ggcctcgggc gcggtggccg
    13141 gtgcgaggtc cgccaggccg gtggtcacca ccacccggtc gcggccgccg cgcttggccg
    13201 cgtagagggc ggtgtcggcg gcgttgacca gctcgtccgg cgtctgcggc ggctcggcgg
    13261 tggtgccccc gatcgacacg gtgaccgcga ccggagtgtg gccgtccacc aggacgggga
    13321 ccgcgttgat ctgggtgcgg atccgttcgg ccacggccgt caggtgctgc gggtccgtgg
    13381 cggtggtcag tacggcgaac tcctcgccgc cgaagcgggc cacgacgtcg ccggcgcggc
    13441 aggtggcgcg cagccgccgg gcgacctcga ccaggacctg gtcgccggcg gggtggccgt
    13501 acgtgtcgtt gatccgcttg aagtggtcga cgtcgagcag caggagggcg agcggaccgc
    13561 cggaccgggc cgcgcgctcg ctctccaccc gcagctgctc ggacaggaag cggcgggtgt
    13621 agaggccggt cagggcatcg gtgatggcca gccggcgctg cgccgcgatg aggcccgcca
    13681 tgcgcaccag cacgagcagg aagagcaccg ccgaggcgcc gacgacgacc aggtcggacc
    13741 gggccgcacc ccgcaggttc tgcaccacca gcacggccgg ggccatcgcg gtggcgaagc
    13801 cgagcagcac cacgcggtac ggggtggcgc ccgagcgggg ctccgccggg tcggccaggt
    13861 gccgcatcga cgggtgcagc ccggccgcgc cgagcgcgac gtagccgagc agccacagcg
    13921 catcggtcca cccgccgtcg gcgaacgagc cggtcagggt gagcaggccg taggcggtgt
    13981 cggcgaacag gttcagggcg aggaaggcca gcagcaggtg gtaggccggc tggcggacgc
    14041 cgccgctgag catcagccgg atggccacgg tgagcacgca caggtccatc accgggtagg
    14101 cggtggccgc gacccggtcc accgtgtcga tgtccggggc ggtgaccgtc gggtggatga
    14161 ggaacaccca ccacagcacc gcggcgccca cggcgaggat cgtggtgtcg accagcgcgg
    14221 ccgtgttgcg ctgcggggac cgccgccggg tcagctgcac cagggcggcg gcgacgaaga
    14281 agtactgggc gaggtagagc acgttcgccg ccaccgggta gctggcgtcg tgctgggagg
    14341 cgatgtagta ggtgacgtcg cccgaggtgt acatcacctg gccggcgacg aacagccacc
    14401 agatcgagcc gggccgcggc cggtgccgcc ggatgcccac cgcgagcgcg accgcggtcg
    14461 acccgctgac caggcagtag agcaccgtct ggagcacggc cccggcgtcg gtggccggca
    14521 ccgtgtagta gccggcgatg ggcagcagcg ccgccgccga ccaggcgatc caggcccgcg
    14581 accacgcgga cgtcgtacgc gcggcggcct gtcccgggcg atccacagat gtcacgtcac
    14641 catgacatca gcgcggcatg caccggccgg ttgtcccagc gttgccagac ggtagccgtc
    14701 atcggccgca acagggcctt cgcaagattg tcacattcac aggcattgat gctttctggt
    14761 gaatttctct aggctgaagc tcctcgaatc gctgcgcgcg aggggagacg gccctggaca
    14821 ccgacgcacg gaccgcgacc gccctgttcg gcagggcgcc cctgctcgcc gccgtcgagg
    14881 cacgcctggc ctcgggcgga ggcgtggcgc tgcacgggcc ggagggcatc ggcaagaccg
    14941 ccgtgctcga cgccgtggcc gccgcggccg ccgcgcgcga cgaactggtc gtccgggtgc
    15001 ggcccgcggc ggccgaccgg ctgcttccgt acgcggggat cgccgatctc gtggcgcagc
    15061 tgccggagac cgccgtcgcg gccctgcccc cggcccaccg tgcggccctg gcgatgttgc
    15121 gccagggcgc cgccccgcgc accggcgccc cggcgctggc ccgccgcctg gtgctgccgg
    15181 gcctgctcgc gcactgtgcc cgggcccggc cggtgctgct ggtgctcgac gacgtgcagt
    15241 ggctcgacgc cgagtcggcc gagctggtgg gctttgcgat gcgccggcgt cccgggccgc
    15301 gggtgcgggt ggtcgccgcg cagcgcctgc cggacgacgc cggacggcac cgcgccgccc
    15361 ggctgtgccc ggccccggtg gcggacctgc tggtgccgcc gctggacgcc gacgatctca
    15421 gcgcgctgct ggaggcgcgg ggcctgccct gccgggcggc ggcccgcctg cacgaggcca
    15481 gcggcggcaa cccgttcctg gcgctggccc tgggcgccgt cgcgcccggg ccgccctggc
    15541 ggccggcacc gctgcccgag gcggcccggg acctgctgcg ccgccgggtg gccgcgctgc
    15601 ccccgccggt cgccgcgacc ctgctggtgg ccgcgctggc caccgaaccg accctcacgg
    15661 tcctggtccg ggcgggccac gaggacgcgg accgggacct gcgggtcgcc gcggccgccg
    15721 gcgtggtgcg gaccgacggg gagacgatcc ggttcacccc gcccgcgctc gccgacgtgc
    15781 tcaccgagga cgccggcgcc gcccgccggg ccggggtcca cgacgcgctg gccaacaccg
    15841 cgctggacga gacgatcgcc gtacggcacc gggccctgcg cagcggccgc ccggacgcgg
    15901 acgtggcgcg cgacctgctc gaggcggccg agcgggcggt gcgccgcaac gccgctcgca
    15961 cggccgccga gctgtacctc ctcgccgccg accgctgccc ccgcagcctc gccgcccagc
    16021 gcttcgactg gctcgtcgcc gcggcgcgca ccgccaccgc cacgggggtt cccgcggtcg
    16081 ccgggcgggc cgccgaggcg gtcctggccg ccgccgacgc cccggccgcc caccgggtcc
    16141 aggcccggat cgtgctgctg gacctggccg gacaggccct cgcggagatg gacgagacgt
    16201 tcgccggcgc gctcaacgag gccggcaccg acgtggcgct gctcgccccg gtgaaactgc
    16261 ggctggcctg ggccgcgatg ctgggcggtg cggtgcgctc ggccggggtg tgcgccgccg
    16321 aggcggcgcg ggcggcccgc gcggccggcg acccgacgac cgaggccatg gcgctcagct
    16381 ccctcgccca ggtccagcgg ctgcgcggcg agccgcagtg gaccggcacg ctgcgccggg
    16441 cgctgtcgct gcccgcgccg caggtgccgg gcctgctgca tctgagcccg cgctacctgg
    16501 cggcccggtt cgccatgatg gacgaccggc tcgacgaggc ccgcgccgag ctgctcaccc
    16561 tgctcgccgt cgccgagcac gaccgcgccg gcgaggccct ggtggaggtg ctgcgcagcc
    16621 tctccgaggt ggccacccgg gccggccggt gccgcgaggc gctgcggtac gcccaccgcg
    16681 ccgtcaccgc cgcccagcag gccggcctga gccccggacc cacctggtac acggccgccg
    16741 tggccgagct ggccgggggc agcctcgccg ccgccagcgg gtacgcccgc cgcggcgtcc
    16801 gcgcctccga gcaggagggc gacagcctgt atctgcggcg gagcctgcac gccctcggac
    16861 aggcccagct gcgcgccggc gacacccggg gcggcgtggc gaccctgcgc cggctgagcg
    16921 agctcgccga cggcgccgcg gacccgatga tcgtgcgctg gcagggcgac ctcgcgggcg
    16981 gcctggccgc gctcggcgag cacgacgagg ccgccgcgac cctcgcggcg gcgcgggccg
    17041 ccgccgaccg gctgggcgcc gccccgggcc tgcacggcta cctcgaccgg gcgaccgcgg
    17101 tggtgctctc cgagcggggc caggccgact ccgcggtgct gctgtgcgcc accgccgcgc
    17161 agcacttcgc ggacctgcgc cagcccctcg agcaggccca tgccctgctg gtacagggcg
    17221 gggcggaacg gcgccgccgc cggtacgccg ccgcccgcgc cgccctgggc gcggcgctcg
    17281 ccctgttcct ggccgccgag gcgaagccgt ggaccgagca ggcccggcac gcgttcgcgc
    17341 gtaccgaggg aaccgccgcg cccccctccg acctggggct gacctcgacc gaggcccgca
    17401 tcgcgggact cgtgcgcgac ggggccagca accgcgagat cgccggccgc ctgttcctca
    17461 gcgtcaagac cgtcgaggcg accctgacca gggtgtaccg caagctcggc gtccgctcgc
    17521 ggacccagct ctcccagcgg ctcccggcga caagggtttt ccccgattcg gtgacgaccg
    17581 tcgatgcata gcgtcactgc tcgacagcct ggttcctccc gaccccggga gagcacccag
    17641 gcctggcccg gaccgggtcg agagaaggag tgatgagcgt gggacgcaga aaactcatct
    17701 cagcatcggc ggcgctcgcc accggggccg cgctgacgct ggccgcggcg ccggcctcgg
    17761 cccagccgca gcgcgcgccc ggcccgccgt ccggtccggc cctggccgcg gcggccgccg
    17821 accggctcgt gcacagcgcc ggcaccgcgt cgctgctgcg ccgctccgac ggcgacacgc
    17881 tcgagcggac cggcgtcgtg cagggcaccc gcgggctgca gtacgtgacg tacgcccgga
    17941 cgttccgggg gctgccggtg gtcggcggcg acgtcgtggt gaccacggac gcggccggca
    18001 cggtcaagga caccgcggtc gcccagaccg caccgatcgc ggtcggcacc accgcgaccg
    18061 tcaccgccgc gcaggccgcc gcggccgccc gcggccggct ggccagcgtg gaccgcgcga
    18121 ccgcgccgcg gctcgaggtg ctcgcctggg gcacgcccac gctcgtgtac gaggccgtcg
    18181 tcgagggccg tacggcgcag cacaagccca gcaacctgca cgtcttcgtg gacgcgcaca
    18241 ccggcaaggt cgtcgagcag gtcgactacg tgcgcgaggg caccggcacc ggctactact
    18301 acggcaacgt cacgatcagc acctccggct ccggctcgtc gtggtcgatg accgacccca
    18361 cccgccccgg cctcaagtgc ggcgggcaga acggcagcgc gtacaccggc accgacgacg
    18421 tgtggggcaa cggctccggg acgaacctgg agaccgcctg cgtcgacgcg ctgtggggcg
    18481 cccagcgtga ggccgacatg ctcagcgcct ggttcaaccg caacggcatc aacggcaacg
    18541 gcaacaaccc gccgatccgg gtcgggctga acgacgtcaa cgcctactgg aacgggtcct
    18601 acacgaactt cggccacaac caggccaaca cccgccaggc gacgccgatc gacgtggtgg
    18661 cgcacgagat gggtcacgcg atcttccagt acacgccggg cggggccggc ggcggcaacg
    18721 agaacggcgg catcaacgag gccaccggcg acatcttcgg cgcgctgacc gaggcgtacg
    18781 ccaacagccc gctcgacccg ccggactacc aggtgggcga ggaagtggac ctggtcggcg
    18841 acggcccgat ccgctacatg tacaacccgt cgctggccgg cgaccccaac tgctggtcca
    18901 cctcgatccc ctcgaccgag gtgcacgccg cggcgggccc gctgaaccac tggttctacc
    18961 tggtcgccga gggctccgcg ccgaccaacg gccagcccgc cagcccgacc tgcaactcga
    19021 gctcggtcac cggcatctcc atccgcaagg ccggcgagat ctactacaac gcgttgcagg
    19081 ccaagacctc cacctggaag tacgccaacg tccgtacggc gtcgctgacc gcggcgaaga
    19141 acctgtaccc gaacagctgc accgagttca acacggtcaa ggcggcctgg aacgcgatca
    19201 gcgtcccggc gcagccgggc gaggcgacct gcacgggcac cccgggcaac gacttctcgg
    19261 tctcggcctc gccggcgtcc ggcagcgtcg ccgcgggcgc ggcggccacc accacgatcg
    19321 ccaccgccac cacctccggt gcggcgcaga ccgtcgcgct gagcgcctcg gggctgcccg
    19381 gcggagccac ggcgacgttc aacccggcgt cggtgacctc gggatcctcc gccacgctga
    19441 cgatctcgac cagcgcgtcg accccgtcgg gcagctaccc gatcacggtg accggcaccg
    19501 gctcggccac ccactcggtg acgtacacgc tgaccgtgac cggcggcccc ggcggcagct
    19561 gcaccgccag caacggcacc gacgtctcca tcccggacgc gggcgccgcg gtgaccagca
    19621 cgatcacggt cagcggctgc gggcgcaacg cgtcggcgac ctccacggtg gcggtgaaca
    19681 tcgtccacac ctaccgcggt gacctggtga tcgacctggt cgcgccggac ggcacggcct
    19741 accggctgaa gaacagcagc atctccgacg gcgccgacaa cgtgaacgcc acctacacgg
    19801 ccaacctctc ggccgaggcc ggcaacggcg cctggaagct gcaggtccgc gacgtgtaca
    19861 gcgcggacac gggccacctc gacacctgga cgctgaccct ctgacccact gacccccccc
    19921 gcctcgcccg gcgacccggg ccgccggact ccggtggccc gggtcatcgc cgtccggaga
    19981 gcaggtgact cacctggggc gggccctcgg cgagcgcctg ggcccgctgc tcgaccgcct
    20041 gatccgcacc ggtcagccgg ccggtgtgct ggcgcaggtg ctcgtcccgg ctgggcacca
    20101 cgtacgcctc cacgaagcgg cccggattct caccgtcgcg gtcgggccgc accacgagga
    20161 cgcgttcgcc gaggcgatgc agcaggtacg gcccgtcgtg gtcgtcgggg tccagctcca
    20221 gatggggctc gggccagaag ccgtctgcat ccacgtaccg acgttgctgg ccagcagggc
    20281 cagccacagg ctgcggaagg ccgcgatccg caacggcgcc cacgccgacg gcgcggccgg
    20341 tacggcggcg ggtgcgggga cggtcaccgg cgatgtctaa ccaccaccga gacgatctac
    20401 caccgtccgg tgcccgcatg ccgccgtgtg tcgttcggcc gatcggtgcc tccccctcgc
    20461 gacgcccggg gcgtagcgtg agtaaccgga catgcggaga ggggcgcttg tgcggacagt
    20521 ctcgatggac acgagcgtcg acggccggct ggatgtggtg ctgcgcgggg agctggactt
    20581 caccaacgcc tcgcaggtcg ccaaggtggt gaaggaagcg atcgtcggcg gccggccgcg
    20641 tgcggtacgg gtgcgcctgg cagaggtcac cttcctggac tcgtccggca tcggcctgct
    20701 ggtgcgggcc atgaaggccg ccggcgaggt cggcgccgac ttccgcgtcg aggagcccac
    20761 cgacaaggtg ctcgaccagc tgcggatgtc cggcctgctg gaggcgttcg gtctgcccca
    20821 gccgccgccg gaaacctgat gatggacggg actccgggct atctgcagcg cctggccgag
    20881 ctggagcaac agatcggcag tgcccggctg agtcccgacg tggtggtcga gcgggccgcg
    20941 gggctgctcg ccgggcggat cggctgccgc atcgacgagg ccctcgccca cctgcggacc
    21001 ctcgcgcgcc agcaggacca ggacctcgct gccgtggcgg cggggatcat ctccgtgctg
    21061 gagacccggc aggcgacgcc ctccgggcgg ctgcgccgca ccgccgagga agtgctccgg
    21121 gtggcccacc agtcgccgac gccacgtcag cgtcaccgac cggcgccgcc cgacgatgcg
    21181 gcgcccggct gggccgacgt cgtgcaacag gtcctggacg ccatgccggg caaccacatc
    21241 gtgctggtcc cgatgcgcga cgacgccggg cggctggtcg actaccggct cgtcgcggtg
    21301 acccactccc tcgtggacct gtccggcaac accggctcgc ggctggtcgg ccggcgggtg
    21361 agcgagtcct atccgacgat cgtcggcggg cccgtgtggc aggcgtgggc cgacgccctc
    21421 gccgacggcc agcagcgtca ggtcgggccc ttcccctacg tgcaccgcga cgacgaccag
    21481 gcctccgagc acctgttgtc cgtacgcgtc cagccggtcg ggcccggcct gctgaacacc
    21541 tgggtccgct ccgacgagca gacccgcctg gccgagcgca tcgcacagac cgaacggctg
    21601 ggcaacctcg gatggggcga atgggacctg gtcaccgacg agaccgtgtg gtccgacgag
    21661 ttgtaccgga tctacgaacg ggaccccgcc gacggccccc tgccccgcga ggagtcggac
    21721 gcgctcggcc tgcccgagga cgagccgctg cgccgggagg ccgcggacgc cttcgggcgc
    21781 ggcgagacgg tcgacctcac cgcccgcgcc atgatcaacg gcaagatcaa gtatctgcgc
    21841 gcggtgatcg acgcggtccg tgacgtggac ggccgcccga tcaagatcta cgggatcatc
    21901 caggacgtca ccgcccggga gacgagccgc ctcaagctcg ccgaggtgca ggaggagctc
    21961 cgcgcacagc aggagagcct gctcgccgag caccgcctgg ccgcgcagct gcagcacatc
    22021 gtgctgccca tcccggacgg cccgatcgag ctcgacgggc tgcgggcggc ggtccgctac
    22081 ctgccggccg agcaggccag ccgggtcggc ggcgactggt accacgcggc cgcggcgggc
    22141 gacggcagca tcgtcctggc cgtgggcgac gtcgccgggc acggcctgca ggccgccgcc
    22201 accatggccc agctgcgcca cgccctcgcc gccctggccg tgacgaccac gtcggacccg
    22261 gccgatctcc tcgcccacct caaccggctg ctctacgccg cggacgccga gacgggcacc
    22321 gccgcggtcg cccgcttcga cccggccacc ggcgacctca cctgggcccg ggccggacac
    22381 cccgcgccgc tggtcgcccg ggccggggcc gtcaccgagc tgtccggccg gccggggccg
    22441 ctgctcggcg cgatccggag cgcgagctac gacacctcca ccacgcgcct ggatctcgcc
    22501 gacgtcctgc tgctctacac cgacggtctc atcgagcacc gctcgcagac gctcgacgag
    22561 ggcctggccc ccctgctcgc cgtcctccgg cgggtcaccg ccgcgcccgg cccccctccg
    22621 ctggaggacc t
//
