LOCUS       NZ_BMMP01000002        10870 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces daqingensis strain CGMCC 4.7178 sequence02, whole
            genome shotgun sequence.
ACCESSION   NZ_BMMP01000002
VERSION     NZ_BMMP01000002.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces daqingensis
  ORGANISM  Streptomyces daqingensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 579712)
  AUTHORS   Sun,Q. and Zhou,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 66X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014645895.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 03:14:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,667
            CDSs (total)                      :: 5,602
            Genes (coding)                    :: 5,509
            CDSs (with protein)               :: 5,509
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 58
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 93
            CDSs (without protein)            :: 93
            Pseudo Genes (ambiguous residues) :: 0 of 93
            Pseudo Genes (frameshifted)       :: 35 of 93
            Pseudo Genes (incomplete)         :: 69 of 93
            Pseudo Genes (internal stop)      :: 2 of 93
            Pseudo Genes (multiple problems)  :: 13 of 93
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:17:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 21389
            Orig. end                         :: 32259
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMMP01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..10870
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="butyrolactone"
                     /region_number="1"
                     /rules="AfsA"
                     /tool="antismash"
     cand_cluster    1..10870
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /kind="single"
                     /product="butyrolactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10870
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:5870](+)"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5870
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
     misc_feature    complement(31..45)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.5"
                     /tool="antismash"
     gene            complement(1032..1997)
                     /locus_tag="IEY56_RS02510"
                     /old_locus_tag="GCM10012287_05080"
     CDS             complement(1032..1997)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003946654.1"
                     /locus_tag="IEY56_RS02510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012287_05080"
                     /product="virginiamycin B lyase"
                     /protein_id="WP_229711529.1"
                     /transl_table=11
                     /translation="MPTEHHHSVPPYTGSPPAGYSTRLVPVPGRGPYAVAEDADGTLWV
                     TLAGSGQIAELNDREPPRLHSAGRADARPTVVAAGPDGRTMWFTEFLAGRVVGVRPGLD
                     PVCVPLPAGDEGPYGVTAGPDGAVWFTELTANRIGRLVPAAVGDEREQPCAVEEFALPV
                     SDGSPAGITAGPDGGLWFTLSGADAIGRIDPGGEVTVHRLPSAGARPVHIAAGDDGAMW
                     FTQNGAGSIGRITADGQIDEVPLPGGPATRPHGVAAAAGGGCWFTEWGTCRIGRVDASG
                     RVSTWRLPPGVSEPHGIAATGADTVWAAMESGALVGLTLN"
     gene            complement(2153..2980)
                     /locus_tag="IEY56_RS02515"
                     /old_locus_tag="GCM10012287_05090"
     CDS             complement(2153..2980)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019330964.1"
                     /locus_tag="IEY56_RS02515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012287_05090"
                     /product="AfsR/SARP family transcriptional regulator"
                     /protein_id="WP_189035395.1"
                     /transl_table=11
                     /translation="MDIGVLGALAVRQNGVSITPTAPKPRQVLALLALHADKVVPVSVL
                     TEELWAGTPPRSARTTLQTYVLQLRELIAAALEDGGASGEEQLSAKDVLVTSPGGYMLN
                     SEGGTSDVREFERLAGLGYRAMDAEDYRGAAQQLRAALDLWSGSALTDVHAGTHLETEI
                     RRLEESRLCALDQRIEADLHLGRHRELLSELTVLVSRYRTHENLHAQFMLALHRSGRRG
                     DALEVYQRLRGTLVGDLGLEPSEGLRRLQHSVLMSNAEQPSEADDSQSLVRSA"
     misc_feature    2976..2991
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.25"
                     /tool="antismash"
     misc_feature    complement(3115..3128)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.89"
                     /tool="antismash"
     gene            complement(3385..4023)
                     /locus_tag="IEY56_RS02520"
                     /old_locus_tag="GCM10012287_05100"
     CDS             complement(3385..4023)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006344625.1"
                     /locus_tag="IEY56_RS02520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012287_05100"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_189035396.1"
                     /transl_table=11
                     /translation="MVKQERAARTRQLLLQAAAEVFVREGYARASLSTISARAGVSNGA
                     LHFHFETKNLLAEAVEECAAATLRRIAVAANEAPGSALQRLIDATHRLMAALHQDVVVR
                     AGFELCAAAGRRGGGPDLRREWQDRVVKLLAEAERKGDLAEGVTAADAAMAVVTSTVGF
                     EMLGSRDRAWVAPETVARFWELLLPRLSRPEVLGELSTRCADVVGPPPV"
     misc_feature    complement(4835..4849)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.88"
                     /tool="antismash"
     gene            5001..5870
                     /locus_tag="IEY56_RS02525"
                     /old_locus_tag="GCM10012287_05120"
     CDS             5001..5870
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     butyrolactone: AfsA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387457.1"
                     /locus_tag="IEY56_RS02525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012287_05120"
                     /product="ScbA/BarX family gamma-butyrolactone biosynthesis
                     protein"
                     /protein_id="WP_229711531.1"
                     /sec_met_domain="AfsA (E-value: 7.6e-24, bitscore: 78.6,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKEFVHRAAVAEVLLTSWAPRSGTEFRVTAQWPRCHSYFAPVDG
                     RYDPLFAAETIRQIGALLAHTGFDVPLGHKFLMWDLEFAVVPERLRIAGAPASLDIDVS
                     CTEVDRRPGGALKGLRYEAVLRQDGQTVATGGASFTCTRPEVHDRLRRDRPRSDESPLP
                     LTAPLPPQHVGRTSPVDVVLSPIGEAGRWLLRADTRHPVLFDHPVDHVPGMVLLEAARQ
                     AAHALLGHAPFPVSARSTFERYAELDAPCMVEARQLPDGEGSLATVLVTATQGGEQLFS
                     STLTAACP"
     gene            complement(5914..6810)
                     /locus_tag="IEY56_RS02530"
                     /old_locus_tag="GCM10012287_05130"
     CDS             complement(5914..6810)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018515158.1"
                     /locus_tag="IEY56_RS02530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012287_05130"
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_189035398.1"
                     /transl_table=11
                     /translation="MILVTGATGTVGREVVRRLPADGPVRVLTRRPDRVGDLPEHVEAV
                     AGDYGDAPSLERALKGVTKVFLLTNAVGGGDDERFLRAVRGTDVRLIVKLSAAAVANPA
                     ADDAITRWQRRCEARLRECGTEWTLLRPRAFMSNTLGWAPLIASGRPVSALYGTSPNSC
                     VDPRDIAEVAVRALTEEGHAGRAYTLTGPEPVSAVDQAACLSRLLGKPVRFEEWDVARA
                     RAAYLRRHPEHVAEALLQSAEQQRAGAKARVEPAVAEVTGRPACSYEQWAADHISRFAD
                     GAASPQQGWAGAGRHPG"
     gene            7004..7681
                     /locus_tag="IEY56_RS02535"
                     /old_locus_tag="GCM10012287_05140"
     CDS             7004..7681
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008406752.1"
                     /locus_tag="IEY56_RS02535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012287_05140"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_189035399.1"
                     /transl_table=11
                     /translation="MAMQDRAIRTRRKILEAAASVFGERGYQAATIADILSTAGVTKGA
                     LYFHFASKEQLAQGVLRAQEGQDPVPSRTCKAQELVDMVMVYVHRLQTDSMVRAGVWLA
                     LNQQAADLDRSGPFLTWSETLTELLEAAREQGELLPHVKPAETARVIVGAFAGVQAMSQ
                     TLSDYADLGERIAELLRHILPNVVISSVLASVALDGDRGTKVSAEIAAEAETDGQRLET
                     VGG"
     gene            8102..9751
                     /gene="abc-f"
                     /locus_tag="IEY56_RS02540"
                     /old_locus_tag="GCM10012287_05150"
     CDS             8102..9751
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="abc-f"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019324457.1"
                     /locus_tag="IEY56_RS02540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012287_05150"
                     /product="ribosomal protection-like ABC-F family protein"
                     /protein_id="WP_189035400.1"
                     /transl_table=11
                     /translation="MPTQISCRSVTKAYNGLLVLDSVTVTLTTGERTGIVGENGSGKST
                     LLRLLARAEEPDQGEVVVQADGGVGYLPQESSFPPRHTVQQAVDVALGDLRSLERRMRR
                     LERLLAEDESALAEYGEVTTAFELRGGYEADARVERALHGLGLVDLPRDRAVGDLAGGE
                     QVRLRLAALMAAAPEVLLLDEPTNHLDDEALTWLEEHLRTRRGTTVAVSHDRTFLERVT
                     GTLLEVDGDRHTVTRYGNGYDGYLKGKAAARQRWEESHLRWKADVEAVRETAETTARRV
                     APGRPITDGNKMAYDRAAGRVQQSLASRVRNAEERLRRLLADPVPAPPEPLRFTPVLRA
                     ERLTGTVLEADGVTVGGRLPRTWLTVEAGDRLLITGGNGAGKSTLLRVLAGELAPDGGH
                     VARRGRVGHLPQEPGPGRPGRTLLQAFAEGRTGTPEDHAELLLSLGLFTSDRLTAQVTR
                     LSTGQRQRLALARLLTRSTDTLLLDEPTNHLSPALTEELEEALSTYPGTLVLVSHDRRV
                     RARWRGKHLSLGSGPAAGTRRGGVRRAPSRAR"
     misc_feature    complement(10157..10177)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.4"
                     /tool="antismash"
ORIGIN
        1 cctggggcgc caccgccgtg accggcgcca tggccggcct gatcctctcg ggactgatca
       61 cgcagtacct ggactggccc tggatcttct acatcaacct gccggtggcg gcactcgccc
      121 tggggctgct gccgcggatg ctgcggggcg tgcagtccgt acggggcgcc cagccgctga
      181 actggcgcgg cgcggcgctc ctcacgctgg gcctggcact gctcgtgtac gcgctgctgt
      241 ccgtcgaagg caccggccgt ccgctcgtga ccggcggatg cgccgcactg tcgctggtgc
      301 tgctcgccgg gttcgtcctc gaccagcgcc ggtccgccga cccgctcgtc gccgccgggg
      361 tgttcagctc tcccgtgcgc tcgagggcgc tggtgtccgg cgtgctgctc tgcgccgcca
      421 ccttccaggg cttcctggtg ctgacgctct acctgcagaa gggcctcggc tggtctccgc
      481 tgctggcggg cctcggctac gtgccgttcg ccctggggtc gctagccggc gtgaagtgcg
      541 gcgagcgggt cacggtccgc ttcggggcgg gccgggtgct caccgcggcc tgtgccggcg
      601 ccggagcggg agcgctgctg ctggcgttcg ccgcggcatg ggaactctcc tacgccggac
      661 tgctgcccgg cattctgttc ttctcgctcg gcgtcggcgc cggcctcccg gcggcgacgg
      721 ccgccgccgc gcagggtgcg ggcccggagt cctccggcgt catcgcgtcc ctggtcaact
      781 ccagccagca actcggcggc gccgtgggcc tggccctctc cggcatcgcg ctgggcgggt
      841 cgggtctcgg cttcgggacg gccctggcgg tgaccgcggc cgcggccgta ctcgcctgcg
      901 gctgggcggc ggcggtggtg cgcagcgagg aggccgtccc ctccaccacg gcctgacggg
      961 ctgcctgccg cccgagcgga cggaccaggc ggcctgcccc agcggtcggc gcaagggttc
     1021 tgccggggcg gtcagttcag ggtgaggccg accagcgcac cgctctccat ggccgcccac
     1081 accgtgtccg ctccggtggc cgcgatcccg tgcggttcgc tgacgccggg cgggagtcgc
     1141 cacgtcgaca cccgcccgga cgcgtcgacg cgtccgatac ggcaggtgcc ccactccgtg
     1201 aaccagcagc ctccgccggc tgctgcggcg acgccgtgcg gacgggtggc gggcccgccc
     1261 ggcagcggca cctcgtcgat ctgcccgtcg gcggtgatgc ggccgatgct gccggcgccg
     1321 ttctgcgtga accacatcgc cccgtcgtcg cccgccgcga tgtgcaccgg ccgcgcaccg
     1381 gcggacggca gccggtgcac cgtcacctcg ccgccggggt cgatgcggcc gatcgcgtcg
     1441 gccccgctga gggtgaacca cagtccgccg tccggaccgg cagtgatccc cgcggggctg
     1501 ccgtcggaga ccggcagggc gaactcctcg acggcgcagg gctgttcacg ctcgtctccg
     1561 acggcggcgg gcacgagccg cccgatccgg ttcgcggtca gctcggtgaa ccacaccgcg
     1621 ccgtccggcc ccgccgtgac gccgtacggc ccctcgtccc cggcgggcag aggcacgcac
     1681 accgggtcaa gtcccgggcg gacgcccacg acgcggcccg cgaggaactc cgtgaaccac
     1741 atcgtccgcc cgtccggtcc ggcggcgacg acggtcggcc tggcgtcggc ccgcccagcg
     1801 gaatgcagcc gcggcggttc ccggtcgttc agctcggcga tctgcccgga cccggcgagc
     1861 gtcacccaca gcgtcccgtc cgcgtcctcg gccaccgcgt acggtccccg tccggggacc
     1921 gggaccagcc gggtcgagta gccggcaggc gggctgccgg tgtacggcgg gacggagtgg
     1981 tggtgctctg tgggcaagac gtgctcccgt ggtggtgccg cggcccggcc gggagggcgt
     2041 ccgcccctcc ggcacggcct ggggaatcag ctgcgcagcc cgacgaaggg ctctgggacg
     2101 gggtcggcct ggaccgcgac ggcggcgacc gtcggggaga gcggcggacg cctcaggccg
     2161 agcgtacgag gctctggctg tcgtcggcct ccgacggctg ctcggcgttg gacatgagga
     2221 cggaatgctg caacctgcgc agcccctcgg acggttcgag gcccaggtct cccaccaggg
     2281 tgccgcgcag ccgctggtac acctccagcg cgtcgccccg gcgcccggac cggtgcaggg
     2341 cgagcatgaa ctgggcgtgc aggttctcgt gagtgcggta ccggctgacc aggacggtca
     2401 gttcggagag cagttcgcgg tggcggccga ggtgcaggtc cgcctcgatc cgctggtcga
     2461 gggcgcagag ccggctctct tcgagacggc ggatctccgt ctcgagatgc gtgccggcgt
     2521 ggacgtccgt gagcgcggag ccggaccaca ggtcaagcgc cgccctcaac tgctgggccg
     2581 caccccggta atcctcggcg tccatcgccc ggtagccgag cccggccaga cgctcgaact
     2641 cgcggacgtc gctcgtgccg ccctcgctgt tcagcatgta gcccccgggc gaggtgacca
     2701 gcacgtcctt tgcgctgagt tgctcctccc cggaggcccc gccgtcctcc agcgcggccg
     2761 cgatcagttc gcgcagctgc agcacgtacg tctggagcgt ggtccgggcg ctgcggggag
     2821 gtgtgccggc ccaaagctcc tcggtgagta cggataccgg caccaccttg tcggcgtgca
     2881 gtgccagcag ggcaagcacc tgccggggtt tgggagccgt cggcgtgatc gaaacgccgt
     2941 tctgccgcac tgccagcgca ccgagtacac caatgtccac gccgttttcc ccctgtttgg
     3001 ctggtctggt cgcatcgagt cctgcacgac tcgatctctg ctgtcggggt cacctcgaac
     3061 ccgaagggac tcttccggtg cgagggtcct gattagagaa cagggcgcac tgtctgtcaa
     3121 tataaaaccg ttcacgtggt ttgttttatc ggacacatcg tcacctcgca ccctccgccg
     3181 ccggctgccg ggcacccgtc cggcgcgagc ttcgcggagc gcgtcaactc cgccataccc
     3241 agcggcacct gcgacattct cgacggaccg tggagtgctc caacccgagg ctggagcaca
     3301 gtcggtgaag gcgacagggc gccccgaagg agtccagcgg agacacgttt agaaaccgcg
     3361 tggacggttt atgcggcgga tccgctagac cggtggcggc ccgacgacgt cggcgcagcg
     3421 ggtgctgagc tcaccgagca cctccgggcg ggacagccgc ggcagcagca actcccagaa
     3481 gcgcgccacc gtctccgggg ccacccaggc acggtcgcgc gagccgagca tctcgaaacc
     3541 gacggtggac gtcaccacgg ccatcgcggc gtccgcggcg gtgacgccct cggcgagatc
     3601 acccttccgc tcggcctcgg cgagcaactt cacgacccgg tcctgccatt cgcgccgcag
     3661 gtcgggcccg ccgccccgcc gtccggccgc ggcgcagagc tcgaaccctg cccgtaccac
     3721 gacgtcctgg tggagagcgg ccatcaggcg gtgcgtcgcg tcaatgagac gctggagagc
     3781 gctgcccggg gcctcgttcg ccgcgacggc gatgcgccgg agggtcgcgg ccgcgcactc
     3841 ctcgacagcc tccgcgagca agttcttggt ctcgaaatgg aagtgcagag ccccgttgct
     3901 cacaccggcc cgcgcgctga tggtgctgag cgaggcgcgc gcatatccct cccgtacgaa
     3961 cacctcggcg gccgcctgca gcagcagctg cctggtgcgc gccgcgcgtt cctgcttcac
     4021 catcgatcgt ctcctgacat cggggcgtct gcgtgccgga ccccggggcg gtgcgccacg
     4081 gcccggacct gcgggaccgc gacactcccc caccagcggg ctctcctttt ctcgcggcgg
     4141 cggcgccgcg gttcgcggaa cgccccgcct gcaggccggg ggagctgtgc gaacaccggc
     4201 gcgatccggt ccgggccgac cggcagggca ccggccgcca ccagggcacg acgcccgcgc
     4261 ggatgcacat cgtgaggcgc acagctctcg gaaggcccac ggtaacaaac cgcttatgcg
     4321 gttttcacgt gctctgccag gcggacgtat tggcttcacg tcgcatcgga cgccggtccc
     4381 gcaccccggc cctcgccgac ggccgcgccc ggcacgtgcg gcgacgcagc catgccgcac
     4441 cctgccccgc ccgcggccat ggccttccgg acacgcttca gcacacacct cgagaacggc
     4501 tcgcgcgcta ctcgaagaag cgggccccaa cacacggcga gtacacggaa gttggaagtt
     4561 cctgaccctc tggcgtcgag cggaaccggc ctcccggccc gctcgacccc gccacgagcg
     4621 cggcgactcg acgcactccg cggcgagccc cgggaagcga ctgcgcaccc ctgtccggat
     4681 ctccccggcg agagcgccat gccagttgcc gcgcttcccg cggcggccac ctgcacctac
     4741 gccggcaccg gaatcttccg ccccggcgag tacagggaat ctgtagaaac taaaccggat
     4801 ggtatgtatc ttacggcaac gaggggtccg gcggatcaac acccctaatc tgtaagttct
     4861 gttgcagtca atcggggaat atcatgatcg cgagcactgc ccaggtcacg ccctgcttgt
     4921 ccggaacacc ggagggtacc ggcccgcacc ctgcacacct aagccaggcg ctgtcccact
     4981 ttccgccgct gacgaccacc gtgcccaagg agttcgtgca ccgggccgcg gtcgccgagg
     5041 tcctgctgac cagttgggcc ccccgcagcg ggacggaatt ccgcgtcacc gcccaatggc
     5101 cgcgctgcca cagctatttc gccccggtcg acggccgcta cgaccccctg ttcgccgccg
     5161 agacgatccg ccagatcggc gcgctgctcg cccacaccgg cttcgacgta cccctcggcc
     5221 acaagttcct catgtgggac ctggagttcg ccgtcgtacc cgagcgactc cggatagcgg
     5281 gcgcccccgc cagcctcgac atcgacgtct cctgcacgga ggtggaccgc cgccccggcg
     5341 gcgccctcaa agggctccgg tacgaggcgg tgctgcgcca ggacgggcag accgtggcga
     5401 ccggcggcgc ctcgttcacc tgcaccagac cggaggtgca cgaccggctc cgccgcgacc
     5461 gtccgcgcag cgacgagtca ccgctcccgc tgaccgcgcc gctcccccct cagcacgtgg
     5521 gccgcacgtc gcccgtcgac gtcgtcctct cccccatcgg cgaggccggc cggtggctgc
     5581 tccgggcgga cacccggcac cccgtcctct tcgaccaccc cgtcgaccac gtccccggca
     5641 tggtgctgct cgaagccgcc cggcaggccg cacacgccct gctcgggcac gccccgttcc
     5701 ccgtctcggc ccgcagcacg ttcgagcgct acgccgaact ggacgccccc tgcatggtcg
     5761 aggcccgtca actaccggac ggggagggct cgttggcgac ggtgctcgtc acggccacgc
     5821 agggcggcga gcagctcttc agctccactc tcaccgcggc ctgcccctga cggcggcgct
     5881 tacgcactcc gcgccgggcg gtgcctgcac ccgttacccc gggtgccgcc cggcccccgc
     5941 ccacccctgc tgaggtgacg ccgcgccgtc cgcgaagcgg ctgatgtggt ccgccgccca
     6001 ttgctcgtag gagcacgccg gacggcccgt cacctccgcg acggccggct cgacccgggc
     6061 cttcgcgccc gcccgctgct gctccgcgct ctgcagcagc gcctccgcga cgtgctcggg
     6121 atggcgacgc agataggcgg ctctcgcccg ggccacgtcc cactcctcga accgcaccgg
     6181 cttccccagc agccgggaga ggcacgccgc ctggtcgacg gcgctgaccg gttcgggccc
     6241 ggtcagtgtg tacgccctgc ccgcgtgccc ctcctcggtg agcgcgcgga ccgctacctc
     6301 cgcgatgtcc cgggggtcca cacaggagtt gggcgaggtg ccgtacaacg cggacacggg
     6361 acgcccggag gcgatcagcg gagcccaccc cagggtgttc gacatgaagg cccgcggacg
     6421 cagcagcgtc cactccgtcc cgcattcccg cagccgcgcc tcgcaccgcc gctgccaccg
     6481 ggtgatggcg tcgtccgccg ccgggttggc gaccgcggcc gcggagagct tgacgatcag
     6541 ccgtacgtcc gtgccgcgca ccgccctcag gaagcgctcg tcgtcgccgc cgcccaccgc
     6601 gttggtgagg aggaagacct tcgtcacgcc tttcaacgcc cgctccaggg acggcgcgtc
     6661 gccgtagtcg ccggcgacgg cctccacgtg ctcgggcagg tcgccgaccc tgtccggacg
     6721 cctggtcagg acgcggaccg gcccgtcggc ggggagccgg cggacgacct cccgccccac
     6781 cgtgccggtg gcgccggtca cgaggatcac agcggcgccc cgggggctcc gtcactgccg
     6841 tccctgccgg acggcgcagc cctgaacatc cctgatcccc ctgatgtgac ggggtccgga
     6901 aggcccccgt gaacgcggac atggtaaggc ccggtaagat acaaactcgt cggtttcttt
     6961 gccaggggtc ccccggcgga ccgccggcca catcgggagg gacgtggcta tgcaggaccg
     7021 ggccatccgc acccgccgga agatcctcga ggcggcggca tcggtcttcg gggagcgcgg
     7081 gtaccaggcg gcgacgatcg ccgacatcct ctccaccgcg ggtgtcacga agggcgccct
     7141 gtacttccac ttcgcctcca aggagcagct cgcccagggc gttctgcggg cccaggaggg
     7201 gcaggacccc gttccctcgc gcacctgcaa ggcgcaggag ctcgtggaca tggtcatggt
     7261 ctacgtccac cgactgcaga ccgattccat ggtccgggcc ggcgtgtggc tggcgctcaa
     7321 ccagcaggcg gcggacctcg atcgcagcgg gccgttcctg acctggagcg agacgctgac
     7381 cgagctgctc gaagcggccc gtgaacaggg cgagttgctg ccgcacgtga agccggccga
     7441 gacggcccgc gtgatcgtcg gcgccttcgc cggcgtacag gccatgtcgc agacgctgag
     7501 cgactacgcg gacctgggcg agcggatcgc cgagttgctg cggcacatcc tgccgaacgt
     7561 cgtcatctcc tcggtcctcg cgtcggtcgc cctcgacggc gaccgcggca cgaaggtcag
     7621 cgcggagatc gcggccgagg ccgagaccga cgggcagcgc ctcgagaccg tcggcggctg
     7681 acggcctgtc cggcgtgcgt ctcgcgtctc gccacggggc cgatcgagtc ctgccgctgg
     7741 gtgacgactg cgcccgccgc cacgcggtcg actggcgatc atggccggct cgcacacatc
     7801 tcaccgcgtc ccgtaccggc cgggagcgcc aagtgccgct ccgcaccgca gagttgtcat
     7861 gcgcctcgca ccccggccgg gcgggcgcgg gtgacgccgc gccccaccgc gtccagcggg
     7921 cggccgcctc cgaccggcgg cgcgcgggga ggaagcccgc ttgccctcac cgccggagcc
     7981 gtggcagcgt ccggacgcaa ctgtcgtcgc accagtggag tggtcatgct cttcccgggc
     8041 gctcaccgaa cctcccggcc cacagcggcc gtccagccgt cggacgcccc gaaggacccg
     8101 catgcccact cagatcagct gccgctccgt cacgaaggcc tataacggcc tgctcgtcct
     8161 ggactccgtc accgtcaccc tcaccacggg cgagcgcacc ggaatcgtcg gcgagaacgg
     8221 ctccgggaag agcaccctgc tgcgccttct cgcgcgggcc gaggagcccg accaaggcga
     8281 ggtcgtcgtc caggccgacg gaggcgtcgg ctacctcccg caggagtcct ccttcccgcc
     8341 ccgccacacc gtccagcagg ccgtcgacgt cgcgctgggc gacctgcgct ccctcgaacg
     8401 gcgcatgcgc cggctcgaga ggctcctcgc cgaggacgag tccgcgctcg ccgagtacgg
     8461 cgaggtgacg accgccttcg agctgcgcgg cggttacgag gccgacgccc gggtggagcg
     8521 cgccctgcac ggcctcggcc tggtggacct gccgcgcgac cgggccgtcg gcgacctcgc
     8581 cggcggcgag caggtccggc tgcgcctcgc cgccctcatg gccgctgccc cggaggtcct
     8641 tctgctcgac gagcccacca accacctcga cgacgaggcc ctgacgtggc tggaggagca
     8701 tctgcgcacg cgccggggca cgaccgtcgc cgtctcgcac gaccgcacct tcctcgaacg
     8761 cgtcaccggc acgctcctgg aggtcgacgg cgaccgccac accgtcaccc gctacggcaa
     8821 cggctacgac ggctacctca aggggaaggc ggcagcccgt cagcgctggg aggagagcca
     8881 cctccgctgg aaggcggacg tcgaggcggt gcgcgagacc gcggagacca cggcccgccg
     8941 cgtcgcgccc gggcggccca tcaccgacgg caacaagatg gcctacgacc gcgccgccgg
     9001 acgcgtccag cagtcgctcg cgagccgcgt ccgcaacgcc gaggagcgcc tgcgccgcct
     9061 cctcgcggac cccgtgcccg cgccgccgga acccctccgc ttcaccccgg tactgcgcgc
     9121 cgagcgcctc acgggcaccg tcctcgaggc cgacggcgtc accgtcggcg gacgcctccc
     9181 ccgcacctgg ctcaccgtcg aggcggggga ccgtctgctg atcaccggcg gcaacggggc
     9241 gggcaagagc accctgctgc gtgtcctcgc cggagagctc gcccccgacg gcggccacgt
     9301 cgcccggcgc ggacgcgtcg gccacctgcc gcaggagccc gggcccggcc gccccggccg
     9361 gacgctcctg caggccttcg cggaagggcg cacgggcacc cccgaggacc acgccgaact
     9421 gctgctctcc ctcggcctgt tcacctccga ccggctcacc gcgcaggtca cccggctgtc
     9481 cacggggcag cgccagcggc tcgccctcgc ccggctgctg acccgctcca ccgacacgct
     9541 tctgctcgac gagccgacga accacctctc gcccgccctc accgaggagc tggaggaggc
     9601 tctgagcacc tacccgggca cgctcgtcct cgtctcgcac gaccgccgcg tccgggcacg
     9661 ctggcggggg aagcacctct ccctcggctc cggtcccgca gccgggacgc gacggggagg
     9721 cgtcagaagg gccccgtccc gggcgcgttg aggaaccggg accgggcgcg gccgtcgcac
     9781 cgggccactc cgggcgcccg gcctggtgcc tccgggcccg gccccggaca gcacgcgagg
     9841 cgggctgggg gcgcgtcgcc cccgcagccc cggctgcccg gcccggtccc ggctcccgcc
     9901 ccggctcagc gcgccggcgg gctcgtccat ccgtccggga cgtgggcgat gcggacgcgc
     9961 tgaggatggt cccccacggg gacggagacc gtcttctcgc ccgtgccgaa gtcgatggcg
    10021 gtgacctggt cgctgccgct ctcggagatc acgcaggact tcccgtcgcc gctgaccgtc
    10081 gcccagtacg gcttcgaggc cgtcaccagc gggccttcct ccagagtctc ccggtcgacg
    10141 acggtcgcgt agtcgtccat cgtcccggcg acgcacagct tgtcgccctg cggactcatc
    10201 gacattccgt ggtggcgcga gtcgttgacc caggtggtgc ggtcctcgtc ggtgtcggga
    10261 ttcttcggga gggtcttgtc gcgagtgatc ctgtcctcgg cgacgtcgta ctccaggaac
    10321 ccgttgtaga aggagacctg gaagtacagc ttggactcgt cgggcgtgaa cgccaccggc
    10381 cgtaccgcgt cggagaggtc cttgcggccg aacgcgtcga ggcgctcgcg catgtcgatg
    10441 acctcgacct cctcgaacgt ctccgcgtcc acgacggtga tcttgcggtc gcccttcgtc
    10501 cagtcgagcc acggcgcgtc gctgttcgtc tggacgtcgc cgatggacat gttccacagg
    10561 tgcttcccgc cgtcggtgaa gacgttctcg tggggtttgt cgcccgtctt gaacgagccc
    10621 gcctcctccc cggtctcgat gtcgaggacg tgcacggtgt tggacgtgga ggccgagacc
    10681 gccacccgct tcccgtcggg ggagaccgcc atgtggtcgg agcggaagcc ggagacgggg
    10741 aaacgccagt tgagcttccc cgtcgtcacg tcgatcgaga cgacgtcggc gaagctgggc
    10801 cgggagacga ccatcgactt gccgtccggg gtggagtaca tgtcgtccac gaactggtcg
    10861 tgcccctccc
//
