LOCUS       NZ_BMMN01000018        22470 bp    DNA     linear   CON 22-DEC-2024
DEFINITION  Microbispora bryophytorum strain CGMCC 4.7138 sequence18, whole
            genome shotgun sequence.
ACCESSION   NZ_BMMN01000018
VERSION     NZ_BMMN01000018.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Microbispora bryophytorum
  ORGANISM  Microbispora bryophytorum
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Streptosporangiaceae; Microbispora.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 133514)
  AUTHORS   Sun,Q. and Zhou,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 202X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014645855.1-RS_2024_12_22
            Annotation Date                   :: 12/22/2024 07:39:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,203
            CDSs (total)                      :: 7,136
            Genes (coding)                    :: 7,048
            CDSs (with protein)               :: 7,048
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 16 of 88
            Pseudo Genes (incomplete)         :: 78 of 88
            Pseudo Genes (internal stop)      :: 7 of 88
            Pseudo Genes (multiple problems)  :: 11 of 88
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:18:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 26707
            Orig. end                         :: 49177
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMMN01000018.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22470
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22470
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22470
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12470](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12470)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(1641..1650)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.17"
                     /tool="antismash"
     misc_feature    complement(1681..1697)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.46"
                     /tool="antismash"
     gene            1768..2493
                     /locus_tag="IEY80_RS31940"
                     /old_locus_tag="GCM10011574_64630"
     CDS             1768..2493
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY80_RS31940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10011574_64630"
                     /product="SH3 domain-containing protein"
                     /protein_id="WP_142574941.1"
                     /transl_table=11
                     /translation="MTVAKSTAKSMVPALAAWAVTGWIVAGHPAPALAGQAGSGTGGRL
                     TPGVAAEPASGLRGHPASGVATVRPPGPGDPIASGPYGQVVHEARQGPGLVCSYRLRGV
                     HKGGFLNVRESAGVRHARVATLRPADGGFSGACTAANGWIAVKTAAGTSGFAAARYLHR
                     IDLSGRPSLSCAYRLRHVRKGSFLNVREGAGIRHARVGTLRPAGGNIAGACDATHGWVA
                     VDSAGGIPGWASARYLRRV"
     gene            complement(2676..3533)
                     /locus_tag="IEY80_RS31945"
                     /old_locus_tag="GCM10011574_64640"
     CDS             complement(2676..3533)
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546805.1"
                     /locus_tag="IEY80_RS31945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_64640"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_142574942.1"
                     /transl_table=11
                     /translation="MSANRHRQSPTSGGPLRSLSLHAIVVVTALFVGVPLLYGVLGGFK
                     TTRQLSSNPIGLPSPWVPENYASILASGSFWRMLWNSTYIAVLTTVVVVAVSALAAYVF
                     ARFAFRGREALFTMFAAGLMFPFAVAILPLFVLLRMFGLLDNPLGVILPQAAFGMPMTI
                     IILRGFFRAIPGEIEEAAILDGCSSFGFFWRILLPMARPAVATVSVLAVVNSWNQFMLP
                     LVVFSDDSLFTIPLGVQQFQGQYATDVARVMAYIVVAMLPALGFYAVAERQLVSGLTAG
                     AIKG"
     gene            complement(3530..4456)
                     /locus_tag="IEY80_RS31950"
                     /old_locus_tag="GCM10011574_64650"
     CDS             complement(3530..4456)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013133473.1"
                     /locus_tag="IEY80_RS31950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_64650"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_142574943.1"
                     /transl_table=11
                     /translation="MKTTRPRSLRLRGFTTILLFLLPALVLFFGLVVAPILLAFYASVF
                     KWNGMRGLPTDFIGMANFTRLLADEVFLGDLWHGALLIILSVVIQLPLSLGIAMLLNQR
                     IYGRAFFRLLFFAPYMLSEAITAVLFMMILSPTDGLANYILGWFGIDQLDWFADPSTVM
                     MSVFIVMTWKYFGFHMILYIAGRQGIPKELTEAAQIDGATGWNVFRYVTLPLLGPTIRI
                     SVFLSVIGAIQLFDLIWIITGGGPSHSSETMAVTMFQFGFKRFQVGYASAISVVMFLIS
                     LVFAVLYQRYVMRRDLEGASTVLRDQR"
     gene            complement(4464..5750)
                     /locus_tag="IEY80_RS31955"
                     /old_locus_tag="GCM10011574_64660"
     CDS             complement(4464..5750)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013133474.1"
                     /locus_tag="IEY80_RS31955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_64660"
                     /product="extracellular solute-binding protein"
                     /protein_id="WP_142574944.1"
                     /transl_table=11
                     /translation="MKLSRRGAALLAASALVLGGCGSTGNDAGESKSSAGGKVTVEFWN
                     IWTTDPLKSYGVQAIKDFQAAHPNITIKSVPYENEAFKAKLTTLTQSGKAPDIFQTWGG
                     GVLAQQVDAGLVKDLTADAGPWLGTFTDAALSAYKVGDKQYAIPDDIGMVGFWYNKALF
                     KKAGITEAPGTWSQLIDDVKKLKAAGVTPIALGGKDKWPGHYYWAYLAMRIGGLDALKQ
                     AGDSKDFTGPAFVQAGQKLKELADLQPFQKGYLGATYGDPGGQAATMGDGKAAMELMGQ
                     WAPAVQNDAGKGLGDDLGFFPFPAVDGGQGAVTDAFGGGGGYAIGADAPAEALEFLKFL
                     TDSAEHRKAVATGGLLPVLKGEEDAVTDPNLSVVAKNLAGASGFQLYLDQAFPPAVGQE
                     VNDSVAQLIGGTKTPEQVAQAITETAKSE"
     misc_feature    complement(5718..5720)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    5746..5761
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.75"
                     /tool="antismash"
     misc_feature    5789..5803
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.0"
                     /tool="antismash"
     misc_feature    5850..5867
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.06"
                     /tool="antismash"
     misc_feature    5953..5966
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.82"
                     /tool="antismash"
     gene            complement(6111..6710)
                     /locus_tag="IEY80_RS31960"
                     /old_locus_tag="GCM10011574_64670"
     CDS             complement(6111..6710)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013130418.1"
                     /locus_tag="IEY80_RS31960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_64670"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_142574945.1"
                     /transl_table=11
                     /translation="MAFARSDSGKNPPKMPTAIKLLIAGGFGVGKTTMVGAVSEIRPLR
                     TEETLTDRSVGVDDLSGVEAKATTTVAMDFGRISIGQDFVLYLFGTPGQERFWFVWDEL
                     ARGALGAVVLADTRRLADCFPSVDYFERRGTPFVVAVNCFEGAPVFDLDEVKLALNLGP
                     DVPIMLCDARRRESGKEVLIELVKHAYGKRPTAAAH"
     gene            complement(6691..7065)
                     /locus_tag="IEY80_RS31965"
                     /old_locus_tag="GCM10011574_64680"
     CDS             complement(6691..7065)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013133476.1"
                     /locus_tag="IEY80_RS31965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_64680"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_142574946.1"
                     /transl_table=11
                     /translation="MNTEWNPDEERLLDAPTIRPYVIARGRTEAQDRFDLISLAVTVRP
                     TTGAEIGLDPEHQAIVRLCRRPLSVAEIAAHLDLPAGIVRVLLGDLFDRGFVAVQQPQP
                     EMNVLDERMYKAVLDGLRAL"
     gene            complement(7062..7496)
                     /locus_tag="IEY80_RS31970"
                     /old_locus_tag="GCM10011574_64690"
     CDS             complement(7062..7496)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019632365.1"
                     /locus_tag="IEY80_RS31970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_64690"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_142574947.1"
                     /transl_table=11
                     /translation="MTQKTGASADLAWLLDDLVARIREVEHGIVLSTDGLLLAGSQGLL
                     VEDAEHLSAVASGLQSLARGVGERFQGGSVRQTIVEMKSAYLLVTVAGQGACLAVLCSG
                     DADVGLVAYEMAMLVVRVGQYLTSPARTTIDRATGREVRL"
     gene            complement(7493..9772)
                     /locus_tag="IEY80_RS31975"
                     /old_locus_tag="GCM10011574_64700"
     CDS             complement(7493..9772)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013133478.1"
                     /locus_tag="IEY80_RS31975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_64700"
                     /product="nitrate- and nitrite sensing domain-containing
                     protein"
                     /protein_id="WP_229689939.1"
                     /transl_table=11
                     /translation="MRTKVAALLVSLTALWAFAAWVTVREGVNLIWATTIDSEVAQPSE
                     PLLLELQRERRLSVTRAADPARVLRKELQDQRARTDAAVGTFKESATSDKVHLAADDAL
                     RRHLSDTLRRLDGLRETRSAIDAGRLDRTRTEDAYSDVMDSFDAMYGAVATLDDATLAK
                     DGRTLSAMSRARELLAREDAMIAGIFAEGRFTEQDHRQFTQMVGIARFELDRAAADLPP
                     DDRAALDRWRKSPSVTTLRSLEDQLSLSRQVGRPPMVAETQWRGAADAAMTQLQKVVID
                     AGDALVERAVPIAVAVFARLLLAGVLGLVAVIASIVLSVTTARALVRQLEKLREAALEL
                     ANERLPGVVARLAQGEKVDVKAEAPPLDFGPDVIGQVGAAFNTVQETAIRTAVEEAQLR
                     QSIRDILLSLARRTQSLVHRQLTLLDVMERRESDPAELKDLFRIDHLATRMRRNAENLI
                     VLSGASPARAWRRSVPMVDVVRGALAEVEDYTRVTVMPMGETALIGRAVGDLIHLLAEL
                     IENAVSFSPPYTMVQVGGQVVASGYAIEIEDRGLGMSAEDLEATNQRIADPPEFNLSST
                     ARLGLYVVSRLAERHGIRVSLKASPYGGTTAVVLLPRDLVIEGGEALPEEETGSGLPRR
                     EPGSRRIALVGAPDAAPEPAQEVVPVPRAPEPPRPVQSAPPPGGADPDGSASSAGFTPS
                     GLPFRVPQANLAPALAEESTNGDEAEDQEDRSPDDIRKIMGSFQSGTRRGRSEAAKLLS
                     DEEDNL"
     misc_feature    complement(9833..9850)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 17.66"
                     /tool="antismash"
     gene            complement(10001..11581)
                     /locus_tag="IEY80_RS31980"
                     /old_locus_tag="GCM10011574_64710"
     CDS             complement(10001..11581)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013133479.1"
                     /locus_tag="IEY80_RS31980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_64710"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_229689948.1"
                     /sec_met_domain="T2TS (E-value: 3.6e-93, bitscore: 305.8,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDVSLAGPVDVAAAVGELMRDLMSRPWGQVSPSVYETGRLVTLA
                     PWLLGHDERVAYLVATQQPDGSWGVPDGYGLVPTLSATEALLSVLSRGDNGVDRDVLIG
                     AVRRGLRVLSGWLAETAVATLPDTPAIEIIVPALVSLINAHLDGLSECEIGRLPIPEGM
                     SEGPLILIRQRLESGGAPPDKLLHALEVAGRSAASAPSVNPTSIGTVGASPAATAAWLS
                     GCALPDPGHHARRYLEAVALRHGGPVPVGLPITVFERGWVLSWLARAGIQFDVPPEMLA
                     DLRAAIGPEGTPAGAGLPPDADTTSVALYALALLGVPYEPDSLWAFETPTHFCTWQGEE
                     GSSVSVNAHVLDAFGQYAAARPEQAPRYAMVLGRLAAWLRERQRADGSWDDRWHASPYY
                     ATVSCALALYEFGGPESVVAVQSAVRWVLATQREDGSWGRWGGTAEETAYAVQLLLMTG
                     PLTGDGGRPEAVRRGYRYLLRAADQADGPALWHDKDLYLPRAVVRAAVLAALHLAQSSG
                     LVVQQAGQL"
     gene            complement(11574..12470)
                     /locus_tag="IEY80_RS31985"
                     /old_locus_tag="GCM10011574_64720"
     CDS             complement(11574..12470)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.4"
                     /locus_tag="IEY80_RS31985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_64720"
                     /product="terpene synthase family protein"
                     /protein_id="WP_142574950.1"
                     /sec_met_domain="T1TS (E-value: 8.1e-11, bitscore: 34.9,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVKHLAEQETALAADMGRTCALATRCQRDLQASAAAYGELFPAR
                     PFDPAFFAALSMVTAFGSPSASPDELRAVGRASLWIFAVDRLVDQVAGSRADAEALVAE
                     CLAAAETGPGGDAPAVVRFLTDLRDDLSAAPAFAALRPVWLDRLGRTLRAMVREWRWKE
                     EDAPVCLDEYLDGADGCGSSFVNVSHWIRTGDPWTVGHIDELMQVSDEVQRYLRLLNDL
                     ATRERERAQGDANALAFGAGVAEVTARMNEIRGRCLTLLGPIRARSPRAAAYLERQIGF
                     NTGFYGLVDYWGELERA"
     gene            complement(12467..13828)
                     /locus_tag="IEY80_RS31990"
                     /old_locus_tag="GCM10011574_64730"
     CDS             complement(12467..13828)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.5"
                     /locus_tag="IEY80_RS31990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_64730"
                     /product="cytochrome P450"
                     /protein_id="WP_142574951.1"
                     /sec_met_domain="p450 (E-value: 2.3e-69, bitscore: 227.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIDVGPRPTRNAEILPFYRLLAKHPRDPVSAFEEVGRQAAGKLV
                     RLNTGPFRPYLVTHPDHVQHVLRTNQPNYVREGMFWDPLVPLLGGGILSDGETWQESRR
                     VLQPLFTAKYVDSLAERMAEILAEQIDAVVRPGEPFDVVDGISAIVHPTIVRLFFGDRI
                     TRDDIARLIPAYEVAVTATWPRLLLPFVPSTVPLPGDRPFRRSIETINTVVYPRVHEAR
                     RTADEGKDVVSAICRARADEPGEVGDRRIRDDMVSMHGASTETSATALTWVWVALDEHP
                     DLAAKIYEELDEVVGTEMVQPSHLPKLRFLKMFLSELVRLYPPGWILPRKAVETDEIDG
                     VRITAGSTVMVSPYLTHRLEGFWDRPEEFDPERFAPERERERRHRWAYFPFGGGPHQCL
                     GQHLFMIEAQLLMAGLLSRYRPVLTASRPVRPRLASSLRPNQKVKLTFVERARR"
     misc_feature    complement(13909..13924)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.86"
                     /tool="antismash"
     gene            14421..15545
                     /locus_tag="IEY80_RS31995"
                     /old_locus_tag="GCM10011574_64760"
     CDS             14421..15545
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020544469.1"
                     /locus_tag="IEY80_RS31995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_64760"
                     /product="cellulose binding domain-containing protein"
                     /protein_id="WP_223854276.1"
                     /transl_table=11
                     /translation="MSAAMAALLVVLGLLVVRPAEAATVRIMPLGDSITGSPGCWRALL
                     WNKLQNGGFTDVDMVGTLPAQGCGVPYDGDNEGHGGYLVTNVADQNQLPGWLSATRPDI
                     VMMHFGTNDVWSNKPTGTILAAYGTLVDQMRASNPNMKILVAQIIPMNPSTCAECAQRA
                     VALNSAIPGWAAAKTTTASPIVVVDQWTGFSTSADTYDGVHPDDSGNQKMADKWYPALS
                     ALLGGAQPSPSPSPSPSPSPSPSPTRSPSPSPSPSRSPSPSPSPSPSPSSGPSGCGATY
                     TITNQWGGGFQGEVTVRNTGAASISGWTVTWTFTDGQRVTQAWGGKATQTGASVTVRNE
                     SWNGSLGAGASTTLGFIASWNASNSAPVPTCAAA"
     gene            complement(15684..16598)
                     /locus_tag="IEY80_RS32000"
                     /old_locus_tag="GCM10011574_64770"
     CDS             complement(15684..16598)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890631.1"
                     /locus_tag="IEY80_RS32000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_64770"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_142574953.1"
                     /transl_table=11
                     /translation="MTSSLVGKVALVAGATRGAGRGIAIELGAAGATVYVTGRSTRERR
                     SEMNRPETIEETAELVTAAGGRGIAVPVDHLDREQVRALVARIDAEQGALDVLVNDIWG
                     GELLFSWTDRLWEHSLDDGLRILRLAVDTHIITSHYALPLLIRKPGGLVVEVTDGTADY
                     NAANYRVSFFYDLAKTSVNRMAFAQAKELAPHGATAVSLTPGWLRSELMLEHFGVTEAD
                     WRDALAKVPHFAISESPAFVGRAVAALAADPEASRWNGQSLSSGQLAQVYGFTDVDGSR
                     PDCWRYLVEVQDAGRPADVTGYR"
     gene            16607..16948
                     /locus_tag="IEY80_RS37405"
                     /old_locus_tag="GCM10011574_64780"
     CDS             16607..16948
                     /GO_function="GO:0005509 - calcium ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024890.5"
                     /locus_tag="IEY80_RS37405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_64780"
                     /product="EF-hand domain-containing protein"
                     /protein_id="WP_308424436.1"
                     /transl_table=11
                     /translation="MVAHATDRTRARGKTPGPRLGRDPWGQSVLSARVLIAIPEEDGMS
                     EYAATFQLIDADRDGRISAEELVRLMEVLGRPLTLQGAQGAIDRVDADRDGLIDLEEFG
                     AWLSSADQG"
     gene            17007..18158
                     /locus_tag="IEY80_RS32010"
                     /old_locus_tag="GCM10011574_64790"
     CDS             17007..18158
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889216.1"
                     /locus_tag="IEY80_RS32010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_64790"
                     /product="CdaR family transcriptional regulator"
                     /protein_id="WP_229689940.1"
                     /transl_table=11
                     /translation="MPAGVARLLRPRIGDVADQMITEIQRRVPEYARPDDEIYIKVLRL
                     SVNQALQGFLERIENPRAPWDPEVFRTIGRGEASEGRGLEPFQTAMRLGARVAWRRLTE
                     QSEQLDLDPRTLYDLGEAIFVYLDQLADAAAQGFAEARAHAAGEMERRRRRLLDLLLTR
                     PAASPEAVADLARAVGWRLPRTVAGVALEERDGGSPLPVLPPDVLTGLDRNAPCLVVPD
                     PGGPGRVQALESVLRGWRAAIGPAVPLAAAADSLGWAREALDLGTRGILPRRGLLRCAD
                     HMATLVVFKDEDLVAALAEVRLAPLAHLPQSRQDRLAETLLAWLCHGRGVAEVAAALHV
                     HPQTVRYRLRQIEQLYGDALSDPDVRFELEIVLRARQARQGTT"
     misc_feature    complement(17056..17071)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.7"
                     /tool="antismash"
     gene            complement(18177..19301)
                     /locus_tag="IEY80_RS32015"
                     /old_locus_tag="GCM10011574_64800"
     CDS             complement(18177..19301)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013434.5"
                     /locus_tag="IEY80_RS32015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_64800"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_142574955.1"
                     /sec_met_domain="DAO (E-value: 3.1e-42, bitscore: 138.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSAIVVGAGIWGASLALRLADEGWRVTLVEQYAPGHVRQASAGE
                     TRLLRCAHGSDDWYPRLAWQARDDWRRLERRGGEELYVESGLMWFARDPDGWETRSARV
                     LERLDIPCELLDPAEAARRFPGLRGDDLAFVLWEPNAGVLRARRATQVTARLAGAAGVR
                     QVRARAVPYGRGAGVVADGEVLTADRVVWACGAWLPRLFPHEAGHVEVTRQDTFHFGVP
                     RDWTTPPLPAFCDYDLSAYGHGDLDGMGMKVTGDAEGEPYDAESGGRRVLRHTEEQARA
                     YLARRFPSLVGAPVVFSQVCQYALTRDAEWIIAEIDDGVWLLGGESGHGFKHAPALAGY
                     VAEILDGAREPEARFGLHRRPVARGLRTSGGTMP"
     misc_feature    complement(19248..19250)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            19399..20052
                     /locus_tag="IEY80_RS32020"
                     /old_locus_tag="GCM10011574_64810"
     CDS             19399..20052
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012895192.1"
                     /locus_tag="IEY80_RS32020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_64810"
                     /product="IclR family transcriptional regulator"
                     /protein_id="WP_223854277.1"
                     /transl_table=11
                     /translation="MMAAESAQTLERGLRLLRLLADANRGRTPTELAQELGLSRPIVYR
                     LLTTLQAEGFARRDAHGRVHLGFGVLVLAQAVHPLLRAAALPTLRALAEQAGATAHLTM
                     AEGDEGLAVAVVEPSWTDFHVAYREGSRHPLTRGAAGLALLARREGRTEPPLHTSSGHL
                     QEGAQGIAAPIPGLPWLEASVGVVSFTDLDADKVGPLVLEAACRLTSALSEPPR"
     misc_feature    20107..20127
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.73"
                     /tool="antismash"
     gene            20200..21366
                     /locus_tag="IEY80_RS32025"
                     /old_locus_tag="GCM10011574_64820"
     CDS             20200..21366
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543629.1"
                     /locus_tag="IEY80_RS32025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_64820"
                     /product="homogentisate 1,2-dioxygenase"
                     /protein_id="WP_142574956.1"
                     /transl_table=11
                     /translation="MPYYRVVGQVPRKRHVQFRAPDGGLYKEELMGEEGFSSDSSLLYH
                     RHAPTAIVKAEAVDAGAPGLTPNLPLSPRHFRTRDLTPDGDLVSGRMPLAGNSDVRISY
                     AATDAPSELYRDSMGDECVYIARGRARFESAYGALDVAEGDYVVIPTGAIHRWVPEGPV
                     TALVIEAAGHIRPPKRYLSRFGQFLEHAPYCERDLRAPAEPLLVDGEEVPVLVRTRGGL
                     TRLTYAHHPFDVVGWDGCLYPYAFNIQDFEPIVKRTHAPPPVHQTFEGPGFVVCSFCPR
                     PLDFHPEAVPIPYNHHNVDSDEFMFYVGGDYTARKGSGIDVGSISLHPAGFTHGPQPGA
                     VEAAVEAVRQGHTETTEMAVMIDTFRPLDLGQAALACEDTGYAWTWAR"
     gene            21363..22454
                     /gene="fahA"
                     /locus_tag="IEY80_RS32030"
                     /old_locus_tag="GCM10011574_64830"
     CDS             21363..22454
                     /EC_number="3.7.1.2"
                     /GO_function="GO:0004334 - fumarylacetoacetase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006559 - L-phenylalanine catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fahA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012895207.1"
                     /locus_tag="IEY80_RS32030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_64830"
                     /product="fumarylacetoacetase"
                     /protein_id="WP_142575025.1"
                     /transl_table=11
                     /translation="MSFGLGNLPYGVFSRPGEPRRVGVRVGDQVLDLAAALGGDVYAAP
                     SLNPLLALGRASWQETRARAREAAATGDHLIPLAEVTPHLPIEVADYVDFYASFEHASN
                     LGRMFRPDDEPLKPNWRHLPVGYHGRAGTVVVSGTPIRRPCGQRPSFGPSRKLDIEAEV
                     GFVVGVPTRLGERAGAFEDHVFGVALVNDWSARDIQAWEYVPLGPFLGKSFATSMSAWI
                     TPLDALEEARVEGRSQEPEPLAYLRRQAPWGLDLTLHVELNGETVSTPSFRDMYWTPDQ
                     MLAHLTVNGASLRTGDLFASGTVSSVGQPGSLIELTWNGAYPVKLPGETRSFLEDGDTV
                     TISAWTSHGVSLGEVSGKILPAT"
ORIGIN
        1 cgtcctgggg acctggagag cgatgagcac gcacgtcccc gggctgcgga cggcgacggc
       61 ggtcaccgcc gtggcggcgg tgctcggagg caccctcgtc ttcgttccca gcggggagac
      121 cacggcggag ggctccgcca ccggagggac cgccgcgatg gccgccaccg gctccggcac
      181 cggctcccac gagcatcact ccgcctcgga aggatccgcc tccctcatgg gagcggagac
      241 ccggccggtg accgacctgc gcggcccggc cgcaccgccg ccgggcggcg ccgtgcgccg
      301 gttcgagctg acggcccgta cggcgaccgt cacgctgtcc tcggggcgga aggtgccggc
      361 gtggaccttc aacggccagg tccccgggcc gccgctcacc gccgttcagg gcgacctcgt
      421 cgaggtccgg ctgcgcaacg cggacatcac gtccggggtg acgctgcact ggcacggcta
      481 cgacgtgccc tcgggagagg acggcgtgcc cggcctcacc caggaggccg tgccgcccgg
      541 cggggagttc gtctaccggt tcgtcgccgc ccaggtcggg acgtactggt atcacaccca
      601 tgaggtgtcc gacctcggcg tccgcatggg gctctacgga acgctcgtgg tgacgccgaa
      661 ggggaccgcg gccgagggcc tggacctcac gctgcccgtg cacactctcg gcggcgtgac
      721 ggtgacgggc gatcgcgacc agcccctggt ccggcaggcc gcgcccggca cgcccgtacg
      781 gctgcgcctg atcaacaccg acaacacgcc gcatcggttc acgctggcgg gcacgcccta
      841 ccggctggtg gcggtggacg ggacggacct gaacgggccg ggcacgctcg gccgcgtcgg
      901 cctgcgactc gcggcgggcg gccggtacga cctggcgttc acgatgccgt cggaccccgt
      961 gctcctgcgc gtcgacgacc gcaccgactc cgtacgcatc accccggaga gcggaccgcc
     1021 cggcgacggc gccgccgccg caaagggcgc gggcgcgagc gcgaccgccg attccgctgc
     1081 cgattccggc gccgttcccg ccgccgacgg ccagacggcg ggctggccgg agctcgacct
     1141 gacgcggtac ggcgcccccg cccccacgcc gttcacctcg cgaagccgct tcgaccggaa
     1201 cttcacgctc gtcctcgaca gggggttcgc gctgacgaac ggccggccgg cgtacgcgca
     1261 cacagtgaac ggcgccgcct tccccgacat ccccaccgaa gtggtcaggg agggcgacct
     1321 ggtccggctc accgtggtca accgcggccg ggagacccac ccctggcacc ttcacggtca
     1381 tcgggtgctc gtgctctcgc gtgacggccg ctccgtcacc ggcagcccgc tgtggctcga
     1441 caccttcgac gtacagcccg gccaggtgtg ggaggtggcc ttccgcgccg ccaacccggg
     1501 gctgtggatg aaccactgcc acaacctcag ccacgccgac ctgggaatga tgctgcacct
     1561 ggcgtacgag ggagtgacca cgcccttcca cggcgcgcac agcgggtgag ggaatcaccc
     1621 ttttcccccg gtgtgtcgag taaaaaaacc aggcgggaat tcaaccgagg tgtaaacgct
     1681 cggtaatcag atcagaactt cgggtgagca ccactggccc ggatcccccc cggccgggcg
     1741 tggcgatgcc gaccgagggg agagatcgtg acagtggcga agagcacggc gaagagcatg
     1801 gttcccgcgc tggcggcgtg ggccgtcacg gggtggatcg tcgcaggcca tcccgcgccg
     1861 gccctcgccg ggcaggccgg atccggcacc ggggggcgcc tcaccccggg ggtcgcggcc
     1921 gagccggcct cgggactccg ggggcatccc gcctccggag tcgcgacggt ccggccaccc
     1981 ggccccggtg accccatcgc gtcgggacct tacgggcagg tcgtgcacga ggccaggcag
     2041 gggcccggtc tcgtgtgctc ctaccggctc cggggcgtgc acaagggggg cttcctcaac
     2101 gtgcgggaga gcgcgggcgt ccgccacgcc cgcgtcgcca cgctgcgacc ggccgacgga
     2161 ggcttctccg gcgcctgcac cgccgccaac ggatggatcg cggtgaagac cgccgccggg
     2221 acctcgggtt tcgccgccgc ccgctacctc cacaggatcg acctgagcgg acggccctcg
     2281 ctctcgtgcg cctaccgcct ccggcacgtg cgcaagggca gcttcctcaa cgtccgcgag
     2341 ggcgccggca tccgccatgc tcgcgtcggc acgctgcgac cggccggcgg gaacatcgcc
     2401 ggagcctgcg acgccaccca cggctgggtg gccgtggaca gcgccggcgg cattcccgga
     2461 tgggcctccg cccgctacct ccgcagggtg tgacgtcccg ggccggaagg ccccggacgc
     2521 gccggccggc cctcgccgga cgcggcgaat ccgtgctgcc cccgtccccg gtgtccccct
     2581 ggccggggac ggaggccgcc ggcctttcgt tccgatcacc ttggggcgcg cccgtcctgc
     2641 cgttgcccgc gggtccgtac ggcggtgcag gccgatcagc ccttgatggc ccccgcggtc
     2701 aggccgctga cgagctgacg ctcggccacg gcgtagaagc cgagggcggg cagcatcgcg
     2761 accacgatgt aggccatgac ccgtgcgacg tccgtcgcat actgcccctg gaactgctgg
     2821 acgcccagcg ggatggtgaa gagactgtcg tcgctgaaca ccacgagcgg cagcatgaac
     2881 tggttccagc tgttcacgac ggccagaacg gagaccgtgg cgaccgcggg ccgggccatc
     2941 ggcagcagga tccgccagaa gaagccgaac gaagagcacc cgtcgaggat cgccgcctcc
     3001 tcgatctccc ccgggatggc ccggaagaag ccgcgcagga tgatgatcgt catcggcatg
     3061 ccgaaggccg cctgcgggag gatcacgccg agcgggttgt cgagcagccc gaacatccgc
     3121 agcagcacga acagcggcag gatcgccacc gcgaacggga acatgagccc ggcggcgaac
     3181 atcgtgaaca gcgcctcacg cccccggaag gcgaagcgcg cgaacacgta ggccgccagc
     3241 gcggacaccg cgacgaccac gacggtggtc agcaccgcga tgtaggtgct gttccagagc
     3301 atgcgccaga acgaccccga ggcgaggatg ctcgcgtagt tctccggcac ccagggggag
     3361 ggcaggccga tcgggttgct cgagagctgc cgggtggtct tgaaaccgcc cagcacgccg
     3421 tagagcagcg ggacaccgac gaacaacgcc gtgaccacga cgatcgcgtg cagggacagg
     3481 ctacgcagcg gaccgccgga cgtcggggac tgcctgtggc ggttggcgct catcgctggt
     3541 ctcgcagcac ggtggaggct ccttcgagat cacggcgcat gacgtatcgc tggtagagga
     3601 ccgcgaacac gaggctgatg aggaacatca ccacgctgat cgcgctcgcg tagccgacct
     3661 ggaaacgttt gaagccgaac tggaacatcg tgacggccat ggtctcggag gagtgcgagg
     3721 gacctccgcc ggtgatgatc cagatcaggt cgaacagctg gatcgcaccg atgaccgaca
     3781 ggaacacact gatgcggatc gtgggtccga gcagcggcag cgtgacgtag cggaagacgt
     3841 tccaccctgt cgcgccgtcg atctgggcgg cctcggtgag ctccttcggg attccctggc
     3901 gcccggcgat gtacaagatc atgtggaagc cgaagtactt ccacgtcatg acgatgaaca
     3961 ccgacatcat gaccgtcgac gggtcggcga accagtcgag ctggtcgatc ccaaaccagc
     4021 cgagaatgta gttggccagg ccgtccgtgg gcgaaaggat catcatgaac aggaccgcgg
     4081 tgatcgcctc ggacagcatg tacggggcga agaacagcag gcggaagaac gcccggccgt
     4141 agatcctctg gttgagcagc atggcgatgc ccagcgagag gggcagctgt atcaccaccg
     4201 acaagatgat cagcagcgcg ccgtgccaca ggtcgcccag gaagacctcg tccgccagca
     4261 ggcgggtgaa gttcgccatg ccgatgaagt cggtcggcag cccgcgcatg ccgttccact
     4321 tgaacacgct cgcgtagaag gcgagcagga tcggcgccac gacgagcccg aagaagagca
     4381 cgagcgcggg aagcaggaac agaaggatcg tggtgaaccc ccggagcctg aggctccggg
     4441 gtctcgtcgt cttcacgcga cagttactcc gacttcgcgg tttccgtgat ggcctgcgcc
     4501 acctgctcgg gcgtcttggt ccccccgatc agctgggcca cggagtcgtt gacctcctgg
     4561 ccgacggccg gcgggaacgc ctggtcgagg tagagctgga acccggaggc cccggcgagg
     4621 ttcttggcga ccacgctcag gttcgggtcg gtgaccgcgt cctcctcgcc cttcagcacc
     4681 ggaagcaggc caccggtcgc gacggccttg cggtgctcgg cgctgtcggt gaggaacttc
     4741 aggaactcga gagcctccgc gggggcgtcg gccccgatcg cgtagccgcc gccgccgccg
     4801 aaggcgtcgg tgaccgcgcc ctggccgccg tcgaccgccg ggaaggggaa gaagccgagg
     4861 tcgtcgccga ggcccttgcc ggcgtcgttc tggaccgcgg gcgcccactg gcccatcagt
     4921 tccatggccg ccttgccgtc gcccatcgtc gcggcctggc cgcccgggtc gccgtacgtc
     4981 gcgccgaggt agcccttctg gaacggctgg agatcggcca gttccttgag cttctgcccc
     5041 gcctggacga aggccggacc cgtgaagtcc ttgctgtcac cggcctgttt gagggcgtca
     5101 aggccgccga tccgcatggc gaggtaggcc cagtagtagt ggcccggcca cttgtccttt
     5161 ccgccgaggg ctatcggggt gacgccggcc gccttgagct tcttgacgtc gtcgatgagc
     5221 tgcgaccagg tgcccggggc ctcggtgatt ccggccttct tgaacagcgc cttgttgtac
     5281 cagaagccca ccatgccgat gtcgtccgga atggcgtact gcttgtcacc gaccttgtac
     5341 gccgacagcg cggcgtccgt gaaggtgccg agccaggggc cggcgtcggc ggtgaggtcc
     5401 ttgaccaggc ccgcgtccac ctgctgggcg agcacgccac caccccaggt ctggaagatg
     5461 tcgggcgcct tgccggactg ggtgagcgtc gtcagcttcg ccttgaacgc ctcattctcg
     5521 tagggaacgc tcttgatcgt aatgttcggg tgcgccgcct ggaaatcctt gatcgcctga
     5581 acgccgtagc tcttcagggg gtcggtggtc cagatattcc agaactcgac ggtcaccttg
     5641 ccgccggctg agctcttgct ctcgccggcg tcgttcccgg tactaccaca tcccccgagg
     5701 accagtgccg acgccgctaa gagcgccgca cctcgccgac tcaacttcac ggtggtttcc
     5761 cttctggatt ccgaccgaaa ctttcggaac ttgtccgata gtttcgcgat ggggcagacg
     5821 ttacaggggg gttaggttca tatcaacggc tgttgtgcac ctgttacgcg cgctcggcgg
     5881 caaaggaaag tgcggccggt tcactacgcc caaaaaggat tgatcaggag taatcaggcg
     5941 gcattaacgg tcatccgaaa acaaaagggg cgcctgctcg ggcgcgggcc gcgcgaggag
     6001 cgaggtacgc aaagcccgcc ctgccgcgaa acgtaaatcg cgcatagtgc cataaaacgc
     6061 gcatacgcca agaaacccgg acactcccgg gtgaggagcc agtgaaagcg tcagtgggcg
     6121 gcggcggtcg ggcgcttgcc gtacgcgtgc ttgacgagct cgatcaggac ttccttgccc
     6181 gattcccgcc tgcgcgcgtc gcacagcatg atcgggacgt ccgggccgag gttgagcgcg
     6241 agcttgacct cgtccaggtc gaagaccggg gcgccctcga agcagttgac cgcgacgacg
     6301 aagggcgtgc cccgccgctc gaagtagtcg acggagggga agcagtcggc gagcctgcgg
     6361 gtgtcggcca gcacgaccgc gccgagcgcg ccccgggcga gctcgtccca gacgaaccag
     6421 aaccgctcct ggccgggggt gccgaagagg tagaggacga agtcctgccc gatgctgatg
     6481 cggccgaagt ccatggcgac cgtggtggtc gccttcgcct cgacgccgga cagatcgtcg
     6541 acgccgacgc tgcggtcggt cagcgtctcc tcggtgcgca gcggccggat ctccgacacc
     6601 gcgccgacca tcgtggtctt gcccactccg aagcctccgg cgatcagcaa cttgatcgcc
     6661 gtgggcatct tcggcgggtt cttcccggag tcagagcgcg cgaaggccat cgagcaccgc
     6721 cttgtacatc cgctcgtcga gcacgttcat ctccggttgg ggctgctgca cggccacgaa
     6781 accccggtcg aacaggtcgc cgaggaggac ccggacgatt ccggccggca ggtccagatg
     6841 ggccgcgatc tccgcgaccg acagcggcct gcggcacagc cgcacgatcg cctgatgctc
     6901 ggggtccagc ccgatctcgg ctcccgtggt gggccggacg gtcaccgcga gcgagatgag
     6961 gtcgaagcga tcctgcgcct ccgtacggcc gcgcgcgatc acgtacggcc ggatggtcgg
     7021 cgcgtcgagc aagcgctcct cgtccgggtt ccactcggtg ttcacaggcg gacctctctc
     7081 ccggtggccc ggtcgatcgt ggtccgggcg ggcgaggtca ggtactgccc gacgcgcacg
     7141 acgagcatgg ccatctcgta ggccaccagg ccgacgtcgg cgtctcccga gcagaggacg
     7201 gccaggcagg cgccctgacc cgccacggtc acgagcaggt aggccgactt catctccacg
     7261 atggtctgcc gtacggaccc gccctggaag cgttcgccga ctccacgcgc caggctctgc
     7321 aggccggagg cgacggcgga caggtgctcg gcgtcctcca cgagaagtcc ctgcgagccg
     7381 gccagcagca ggccgtcggt ggacagcacg atgccgtgct cgacctcgcg gatccgtgcg
     7441 acgaggtcgt cgagcagcca tgcgaggtcc gcggaggcac cggtcttctg cgtcacaggt
     7501 tgtcctcctc gtcactcagc agcttcgccg cctcggatct gccacgcctc gtccccgact
     7561 ggaacgagcc catgatcttg cggatgtcgt ccggcgagcg gtcctcctgg tcctccgcct
     7621 cgtccccgtt cgtcgactcc tcggcgagcg cgggggcgag attggcctgc ggcacccgga
     7681 agggcaggcc cgacggggtg aacccggccg aggacgcgga accgtccgga tcggcgccgc
     7741 cgggcggtgg ggcgctctgc acaggcctgg gcggctcggg agcccttggc acaggaacca
     7801 cctcctgagc tggttcgggg gccgcatcgg gcgcaccgac cagcgcgatc ctccgggacc
     7861 cgggctcccg ccgcgggagc ccggaaccgg tctcctcctc gggcagggcc tccccgccct
     7921 cgatgacgag gtcgcgcggc agcagcacga ccgcggtcgt gccgccgtac ggcgacgcct
     7981 tgagcgacac cctgatcccg tggcgctcgg ccagacggct gacgacgtac aggcccagcc
     8041 gggcggtgct cgacaggttg aactcgggcg ggtcggcgat ccgctggttg gtcgcctcca
     8101 ggtcctcggc gctcatcccg aggccgcggt cctcgatctc gatcgcgtag ccgctggcca
     8161 ccacctggcc gcccacctgc accatcgtgt acggcgggga gaacgacacc gcgttctcga
     8221 tcagctcggc gagcaggtgg atgaggtcgc ccaccgcgcg tccgatgagc gcggtctccc
     8281 ccatcggcat cacggtgacg cgggtgtagt cctcgacctc ggccagcgcg ccgcgtacga
     8341 cgtcgaccat cggcaccgag cgccgccagg cgcgggcggg ggacgccccc gacaagacga
     8401 tgaggttctc ggcgttgcgc cgcatgcggg tcgcgaggtg gtcgatgcgg aacaggtcct
     8461 tcagctccgc cgggtccgac tcgcgccgct ccatcacgtc gagcagcgtg agctggcggt
     8521 gcaccagcga ctgcgtacgc cgggcgaggc tgagcaggat gtcgcggatg ctctgccgga
     8581 gctgggcctc ctcgacggcg gtgcggatgg cggtctcctg cacggtgttg aacgccgcgc
     8641 ccacctgtcc gatgacgtcg ggaccgaagt cgagcggcgg cgcctcggcc ttgacgtcga
     8701 ccttctcgcc ctgggcgagg cgggcgacca ctccgggcag ccgctcgttg gccagttcga
     8761 gcgcggcctc gcgcagcttc tccagctgac gcaccagggc ccgggccgtg gtgaccgaca
     8821 ggacgatcga cgcgatgacc gccaccaggc cgagcacacc ggccagcagg aggcgggcga
     8881 agacggcgac ggcgatcggg acggcccgtt cgaccagcgc gtcaccggcg tcgatgacca
     8941 ccttctggag ctgggtcatc gccgcgtccg cggcaccccg ccactgcgtc tccgccacca
     9001 tcggcggacg gccgacctgc ctgctgagcg agagctggtc ttcgaggctg cggagggtgg
     9061 tcaccgaggg cgacttcctc cacctgtcca gcgccgcgcg gtcgtccggc ggcaggtcgg
     9121 ccgcggcccg gtcgagctcg aaccgggcga tacccaccat ttgcgtgaac tgccggtggt
     9181 cctgctcggt gaaccggccc tcggcgaaga tgccggcgat catcgcgtcc tcgcgggcga
     9241 gcagttcgcg cgcccggctc atggccgaca gcgtgcggcc atccttggcg agcgtggcgt
     9301 cgtcgagcgt ggcgaccgcg ccgtacatcg cgtcgaagga gtccatgacg tcgctgtagg
     9361 cgtcttccgt ccgcgtgcgg tcgagtcgcc cggcgtcgat ggccgaccgg gtctcgcgca
     9421 ggccgtccag ccgccgcagc gtgtcgctca ggtgcctcct cagcgcgtcg tcggccgcga
     9481 ggtgaacctt gtcgctggtg gccgactcct tgaaggtgcc caccgcggcg tccgtgcggg
     9541 cccgctggtc ctgtagttcc ttccgcagca cccgggcggg gtcggcggcg cgggtcaccg
     9601 agagccggcg ctcgcgctgc agttccagca gcagcggctc gctcggctgg gcgacctcgc
     9661 tgtcgatggt ggtggcccag atgaggttga cgccctcccg gacggtgacc cacgccgcga
     9721 acgcccacag ggcggtcagt gacaccagca gggccgcgac cttggttcgc acacgcgaat
     9781 tccggaagcg catagacata ccacccagca gtcagaacgc cctaacagcg cgtttaccgg
     9841 ccattaacaa tcgcccgccg tataaggcag cccggactgt ccagcgataa gaccgcgccg
     9901 cgcctcgcgc caccctagca aagggctgga aaaccactca acccgcaaga tccggcgaga
     9961 gcatgtccga ataaagcgaa atgcagatca gcccaggtga tcatagttgc ccagcttgtt
    10021 ggacaacaag tccactggac tgtgcgagat gcagggcggc gagcacggcc gcccggacga
    10081 ccgcccgggg caggtagagg tccttgtcgt gccagagcgc cggcccgtcc gcctggtcgg
    10141 ccgcgcgcag cagatagcgg tacccccggc gcacggcctc cgggcggcct ccgtcgccgg
    10201 tcaaggggcc ggtcatgagc aggagctgca cggcgtacgc cgtctcctcg gcggtgccgc
    10261 cccaccggcc ccaggagccg tcctcacgct gggtggcgag cacccaccgt acggccgact
    10321 gcaccgcgac caccgattcc ggcccgccga actcgtacag cgcgagcgcg caggacaccg
    10381 tcgcgtagta gggcgaggcg tgccagcggt cgtcccagct tccgtcggcc cgctgccgct
    10441 cgcgcagcca ggcggcgagc ctgcccagca ccatggcgta gcggggtgcc tgctccggcc
    10501 gggccgccgc gtactggccg aaggcgtcca gcacgtgagc gttcacactg accgaggaac
    10561 cctcctcgcc ctgccaggtg caaaagtgcg tcggcgtctc gaaggcccac aggctgtccg
    10621 gctcgtacgg cacgccgagc agcgccagcg cgtacagtgc gaccgaggtg gtgtcggcgt
    10681 cgggcggcag ccccgctccg gcgggcgtgc cctcggggcc gatcgccgcg cggaggtcgg
    10741 ccagcatctc cggcggcacg tcgaactgga tgcccgcacg ggcgagccag ctcagcaccc
    10801 agccgcgctc gaacacggtg atcggcaggc ccaccggaac cgggccgccg tgccgcagcg
    10861 ccaccgcctc cagatagcgc cgggcgtggt ggccgggatc gggcagggcg cagccgctca
    10921 gccaggccgc ggtcgccgcc ggcgaggctc cgaccgttcc gatcgaggtc gggttgaccg
    10981 acggggcgct ggccgccgat cggccggcca cctcaagcgc gtgcaggagt ttgtccggcg
    11041 gggcgccgcc ggactccagg cgctgccgga tcaggatgag cggcccctcg ctcatcccct
    11101 cggggatcgg caggcggccg atctcgcatt cgctcaggcc gtccaggtgc gcgttgatga
    11161 gcgacacgag cgccggcacg atgatctcga tcgcgggggt gtcgggcagc gtggcgaccg
    11221 ccgtctccgc cagccagccg gacagcacgc gcagcccgcg ccggaccgcg ccgatcagga
    11281 cgtcccggtc cacgccgttg tcgcccctgc tgaggaccga cagcaacgcc tcggtggcgc
    11341 tcagggtcgg gaccaggccg tagccgtcgg gcacgcccca tgacccgtcg ggctgttgcg
    11401 tggcgacgag gtacgccacc cgctcgtcgt ggcccaggag ccagggggcc agggtgacga
    11461 gccgcccggt ctcgtagacg gacggcgaca cctggcccca gggccgggac atcaggtccc
    11521 gcatcagctc gcccacggcc gccgccacgt ccaccggccc ggcaagggag acatcacgca
    11581 cgttcaagct cgccccaata gtccacgagc ccgtagaagc ccgtgttgaa accgatctgt
    11641 cgttcgaggt aggccgcagc gcgcgggctg cgcgctcgta tgggcccgag aagagtcagg
    11701 cagcggccgc gaatctcgtt catgcgcgcg gtcacttccg cgacgccggc gccgaacgcc
    11761 agcgcgttgg cgtcgccctg ggcgcgctcc cgctcccggg tggccaggtc gttgagcagg
    11821 cgcaggtagc gctgtacctc gtcgctgacc tgcatgagct cgtcgatgtg gccgaccgtc
    11881 caggggtcgc ccgtcctgat ccagtgggac acgttcacga aggaggatcc gcagccgtcc
    11941 gcgccgtcga ggtactcgtc caaacagacg ggcgcgtcct cctccttcca ccgccactcc
    12001 cgcaccatcg cgcgcagcgt ccgcccgagc cggtcgagcc agaccggccg cagggcggcg
    12061 aacgcgggcg ccgccgacag gtcgtcccgc aggtcggtga ggaagcgcac cacggcgggg
    12121 gcgtccccgc ccgggccggt ctcggccgcc gcgaggcact cggcgaccag cgcctccgcg
    12181 tccgcgcgcg agcccgcgac ctggtccacc aggcggtcga ccgcgaagat ccacagcgac
    12241 gcgcggccga ccgcgcgcag ttcgtccggc gatgccgagg gcgagccgaa cgcggtgacc
    12301 atcgacaacg cggcgaagaa cgccggatcg aacggcctgg ccgggaagag ctcgccgtac
    12361 gccgcggcgc tggcttggag atcccgctgg caccgcgtgg cgagcgcaca cgtcctgccc
    12421 atatccgcgg cgagagccgt ctcctgctcc gcgaggtgct tgacaatcat ctgcgggcac
    12481 gctcgacgaa cgtcaatttg accttctggt tcggccgcag agaggaggcg agccgcggcc
    12541 tgaccggcct cgatgccgtg agcacgggac ggtagcggct cagcaggccg gccatgagca
    12601 gttgcgcctc gatcatgaac aggtgctggc cgaggcactg gtgggggccg ccgccgaacg
    12661 ggaagtaggc ccagcggtgc cgccgctccc gctcccgctc cggcgcgaag cgctcgggat
    12721 cgaactcctc cggccggtcc cagaacccct cgagccggtg cgtgaggtag gggctgacca
    12781 tcaccgtgga gccggccgtg atcctgaccc cgtcgatctc gtccgtctcc accgccttgc
    12841 gcggcaggat ccagcccggt ggatagaggc gtaccagttc ggacaggaac atcttcagga
    12901 agcgcagctt gggcagatga gacggctgca ccatctccgt cccgaccacc tcgtcgagct
    12961 cctcgtaaat cttcgccgcc aggtcgggat gctcgtcgag cgcgacccac acccacgtga
    13021 gcgcggtcgc ggaggtctcg gtcgacgcgc cgtgcatgct gaccatgtcg tccctgatcc
    13081 gccggtcccc cacctcgccg ggttcgtccg cgcgggcacg gcagatcgcc gacaccacgt
    13141 ccttgccctc gtccgctgtg cggcgggcct cgtgcacccg gggatagacc acagtgttga
    13201 tcgtctcgat ggaccggcgg aagggccggt cacccggcag cggcaccgtg ctcgggacga
    13261 acggcagcag cagacgcggc cacgtggccg tcaccgccac ctcgtacgcg ggaatgagcc
    13321 gggcgatgtc gtccctggtg atccggtcgc cgaagaagag ccgcacgatc gtcggatgga
    13381 cgatggccga gataccgtcg acgacgtcga acggttcccc ggggcgcacg acggcgtcga
    13441 tctgctcggc aaggatctcg gccatgcgct cggccagcga gtcgacgtac ttcgcggtga
    13501 acaggggctg caggacccgg cggctctcct gccaggtctc gccgtccgac aggatgccgc
    13561 cacccagcag cgggaccagc ggatcccaga acatgccctc gcgaacatag ttgggctggt
    13621 tggtccgcag cacgtgctgg acgtggtccg ggtgggtcac cagataaggc cggaacggtc
    13681 ccgtgttgag ccggacgagc ttgccggcgg cctgcctgcc gacctcttcg aaggcggaga
    13741 ccggatcgcg tgggtgcttc gcgagaagcc gataaaaggg aagaatctcc gcatttcggg
    13801 tcggtctcgg accaacatcg atcgacatcc ggtctgctcc ccacctgacg aacgcccaat
    13861 tcgcgaagta tcacatgatc taatcggatt gatcaacaat gcaggtcagt gacacttttg
    13921 tgccggtgtg gccgcacatg cgactacagg cagatttgtc gctagagacg ggtttgacct
    13981 tccggaaaaa ggggaagggc cgggcctcgc ggcccggccc tcctcaggac gtgtcgtcag
    14041 gcgtggctgg tcaccagcag cgcgatgccc acgaggatga cgatgggaat cagccacacc
    14101 acgacctcgc cgaggaactc cttgtacatg gggaccgatc ctctcggtga cgtgcgaaaa
    14161 gttaatctca cgcagcatat tcgctcgtgc ccggcggtgg aacacggcac cgtccccggg
    14221 ccgcggacgg cagaggccgc tgtgcccggg gagaccggac gagccggaag cgacgcccgc
    14281 gtgtgcgccg ccatacctcg gatgaaacgt acatacatca ccgctggtca gggcttttgc
    14341 cgctcctcat ccctgggccg gcggcgggcc gctctctagc atcgcgccgg acggcacgag
    14401 agagggacac gatgtcgagg atgagtgcgg cgatggcggc cctgctcgtg gtgctcgggc
    14461 tgctcgtcgt ccggcccgcc gaggcggcca cggtgcggat catgcccctg ggcgactcga
    14521 tcaccggatc gcccggctgc tggcgggccc tgctgtggaa caagctgcag aacggcggct
    14581 tcaccgacgt cgacatggtg gggacgctgc ccgcccaggg gtgcggggtg ccgtacgacg
    14641 gcgacaacga gggccacggc ggctacctcg tcacgaacgt cgccgaccag aaccagctcc
    14701 cgggctggct ctcggcgacc cgtcccgaca tcgtgatgat gcacttcggc accaacgacg
    14761 tgtggagcaa caagccgacc ggcacgatcc tcgcggcgta cggcacgctc gtcgaccaga
    14821 tgcgggcgag caacccgaac atgaagatcc tcgtcgccca gatcatcccg atgaacccga
    14881 gcacctgcgc cgagtgcgcg cagcgggccg tcgccctgaa cagcgcgatt ccgggctggg
    14941 ccgccgcgaa gaccacgacg gcctccccga tcgtggtcgt cgaccagtgg accggcttca
    15001 gcacgagcgc ggacacctac gacggcgtgc accccgacga cagcggcaac cagaagatgg
    15061 cggacaagtg gtatcccgcc ctgtcggccc tgctcggcgg cgcgcagccg tcccccagcc
    15121 cgagtcccag tcccagtccc agtcccagtc cctcgccgac ccggtcgcct tctccgtctc
    15181 cgtcgccgtc taggtcgccg tccccctcgc cctcgccgtc tccctcgccc tcctccggcc
    15241 cctccggctg cggcgcgacc tacacgatca ccaaccagtg gggcggcggc ttccagggcg
    15301 aggtcacggt caggaacacg ggcgccgcgt ccatcagcgg ctggaccgtc acctggacct
    15361 tcaccgacgg gcagcgggtg acccaggcgt ggggcggcaa ggccacgcag accggggcga
    15421 gcgtgaccgt gcggaacgag agctggaacg gctccctcgg cgccggcgcg agcaccacgc
    15481 tgggcttcat cgcctcctgg aacgcgtcca attccgcccc cgtgcccacc tgcgcggcgg
    15541 cctgacctcg atcgggccgg gcctgttccg gcccggccgc ggcaggcacg cgccccaggt
    15601 gcccgatgtc cctaggcccg atgtccctaa gtggccgatg tccccaggtg cccgatgtcc
    15661 ccccgatgcc cggaccggct ctgtcagcga tagccggtga cgtcggcggg ccggccggcg
    15721 tcctggacct ccacgagata tcgccagcag tcggggcggc tgccgtccac gtcggtgaag
    15781 ccgtacacct gggccagttg gccgctggac agcgactgcc cgttccagcg gctcgcctcc
    15841 gggtcggcgg ccagggccgc caccgcgcgt ccgacgaagg ccgggctctc ggagatggcg
    15901 aagtgcggca ctttggccag cgcgtcgcgc cagtcggcct ccgtcacgcc gaagtgctcc
    15961 agcatgagct ccgaacgcag ccagcccggc gtgagcgaca ccgcggtcgc cccgtgcggc
    16021 gccagctcct tggcctgggc gaacgccatg cggttcacgg acgtcttcgc gaggtcgtag
    16081 aagaacgaga cgcggtagtt ggccgcgttg tagtccgccg tgccgtcggt cacctcgacc
    16141 accaggccgc cgggcttgcg gatcagcagc ggcagtgcgt aatgactggt gatgatgtgc
    16201 gtgtcgaccg ccagccgcag gatgcgcaag ccgtcgtcga gcgagtgctc ccagagccgg
    16261 tcggtccagc tgaacagcag ctcgccgccc cagatgtcgt tgaccagcac gtcgagcgcg
    16321 ccctgctcgg cgtcaatccg cgccacgagg gcccgcacct gctcgcggtc gaggtggtcc
    16381 accggcacgg cgatcccccg cccgcccgcg gcggtcacca gctcggctgt ctcctcgatc
    16441 gtctccggcc ggttcatctc cgagcgccgc tcacgggtgc tgcggccggt cacgtagacc
    16501 gtcgcccccg ccgcgcccag ctcgatcgcg atgccgcgcc ccgcgccccg ggtcgccccg
    16561 gcaaccagtg cgaccttccc caccaggctg ctcgtcatga gacggcatgg tggcacacgc
    16621 caccgacaga acacgggccc gcggcaaaac accgggcccg cggcttggcc gcgatccctg
    16681 ggggcagagc gtgctttcag ctagggtgct gatcgcgatc ccggaggagg acggcatgag
    16741 cgaatatgcg gcgacttttc aacttatcga cgccgacagg gacgggcgga tctccgccga
    16801 ggagctcgta cgcctgatgg aggtgctcgg ccggccgctg acacttcagg gggcgcaggg
    16861 tgcgatcgac agggtcgacg ccgaccgcga cggcctgatc gatctggagg agttcggcgc
    16921 ctggctgagc agcgcggatc agggttgagc agcgctcagc gggcgttgag ccggcgctga
    16981 aaggcgacga cgagttctgg ggcgcggtgc cggcaggcgt cgcgaggctg ctgcgtcccc
    17041 gcatcggcga cgtcgcggac cagatgatca cggagatcca gcggcgggtg cccgaatacg
    17101 cccgcccgga cgacgagatc tacatcaagg tcctgcggct gtcggtcaac caggcgctgc
    17161 aggggttcct ggaacgcatc gagaatccgc gggcgccgtg ggaccccgag gtcttccgga
    17221 cgatcggcag gggcgaggcc tccgaggggc gcggcctcga acccttccag accgcgatgc
    17281 ggctgggcgc gcgggtggcg tggcggcggc tcaccgagca gtccgagcag ctcgacctcg
    17341 acccgaggac gctgtacgac ctgggcgagg ccatcttcgt ctacctcgac cagctcgccg
    17401 acgcggcggc gcagggcttc gccgaggcgc gggcgcacgc ggcgggcgag atggagcgcc
    17461 gccgccggcg gctgctcgac ctgctgctca cccgtccggc ggcctcgccg gaggccgtcg
    17521 ccgacctggc cagggcggtc ggctggcggc tcccccgcac ggtcgccggg gtggcgctgg
    17581 aggaacgcga cggcggctct cccctgccgg tgctgccgcc ggacgtgctg accgggctcg
    17641 accgcaacgc cccctgtctc gtggtgccgg acccgggcgg ccccgggcgg gtgcaggcgc
    17701 tggagagcgt cctgcgcgga tggcgggccg cgatcggccc cgccgtgccg ctcgccgccg
    17761 ccgcggactc gctcggctgg gccagggagg ccctcgacct cggcacccgc ggcatcctgc
    17821 cccggcgggg actgctgcgc tgcgccgacc acatggccac gctggtcgtc ttcaaggacg
    17881 aggacctggt ggccgccctg gcggaggtgc gcctcgcgcc cctcgcccac ctgccccaga
    17941 gccggcagga ccgcctggcc gagaccctgc tcgcctggct gtgtcacggc cggggcgtcg
    18001 cggaggtcgc cgcggcgctc cacgtccacc cgcagaccgt gcggtatcgc ctgcgccaga
    18061 tcgagcagct gtacggcgac gcgctctccg accccgacgt ccggttcgag ctggagatcg
    18121 tcctgcgcgc ccgccaggcc cgccagggca cgacctaggc ccgccggccg ccctccctac
    18181 ggcatggtgc cgccgctggt gcgcaggccc cgcgccaccg gccgcctgtg caggccgaac
    18241 cgcgcctccg gctcccgcgc gccgtcgagg atctccgcca cgtatccggc cagggccggg
    18301 gcgtgcttga agccgtgccc ggactcgccc ccgagcagcc agacgccgtc gtcgatctcg
    18361 gcgatgatcc actcggcgtc cctggtcagc gcgtactggc agacctggct gaacaccacc
    18421 ggcgcgccca ccagcgaagg gaaccgcctg gccagatagg cgcgcgcctg ctcctcggtg
    18481 tgccggagca cccgcctgcc gccgctctcc gcgtcgtacg gctcgccctc ggcgtcgccg
    18541 gtgaccttca tccccatgcc gtccaagtcg ccgtgcccgt acgccgacag gtcgtagtcg
    18601 cagaacgcgg gcagcggcgg cgtggtccag tccctgggca ccccgaagtg gaaggtgtcc
    18661 tgccgcgtca cctcgacgtg tcccgcctcg tgcgggaaca gccgcggcag ccacgcgccg
    18721 cacgcccaca ccacgcggtc cgccgtcagc acctcgccgt ccgccacgac cccggcgccg
    18781 cgtccgtacg gcacggcacg ggcgcggacc tgccggacgc cggccgcgcc ggccaggcgc
    18841 gcggtcacct gcgtcgcccg ccgggcccgc agcactccgg cgttcggctc ccacagcacg
    18901 aaggcgaggt cgtcgccccg cagcccggga aaccgccgcg ccgcctcggc cgggtcgagc
    18961 agctcgcagg ggatgtccag ccgctcgagc acccgggcgc tgcgcgtctc ccagccgtcc
    19021 gggtcgcggg cgaaccacat cagccccgac tcgacgtaca gctcctcgcc gccccgccgt
    19081 tccagccggc gccagtcgtc gcgggcctgc caggccagcc ggggatacca gtcgtccgag
    19141 ccgtgcgcgc agcgcagcag gcgggtctcc ccggcgctgg cctgacgcac gtggcccggc
    19201 gcgtactgct cgacgagcgt cacccgccag ccctcgtcgg ccagccgtaa cgccagcgac
    19261 gccccccaga tccccgcccc cacgacgatc gccgacttca tccaccactc cttgatcgcg
    19321 gacggaccta cgtccgacgt aggctacgtc gaatgtggtt ttcgcctaca ggcgcaccgg
    19381 tgccgcgata atcggagcat gatggcggcc gaatcggcgc agacgctcga acggggcttg
    19441 cggctgttgc gactgctcgc cgacgcgaac aggggccgca cgccgaccga gctcgcccag
    19501 gagctgggcc tgagccggcc gatcgtctac cgcctcctga cgaccctgca ggccgagggc
    19561 ttcgcccggc gggacgcgca cggccgcgtg cacctgggct tcggggtgct cgtgctggcc
    19621 caggccgtgc accccctgct gcgggcggcg gcgctgccga cgctgcgcgc gctcgccgag
    19681 caggcgggag cgaccgcgca cctgaccatg gccgagggcg acgagggcct ggcggtcgcg
    19741 gtggtcgagc cgtcgtggac cgacttccac gtcgcctacc gggagggctc gcgccatccg
    19801 ctgacgcgcg gcgcggccgg gctggcgctg ctcgcgcggc gcgagggccg caccgagccg
    19861 ccgctgcaca cgagcagcgg acacctccaa gagggcgcgc agggcatcgc ggcgccgatt
    19921 ccgggcctgc cgtggctgga ggcgtccgtc ggggtggtca gcttcaccga tctcgacgcg
    19981 gacaaggtgg gcccgctggt cctggaggcc gcctgccgcc tcacgtccgc cctgtccgag
    20041 cccccgcgct gacggtcgcc gttccagcag ccggggctcg gcgcgctcgt ggccgccgtc
    20101 ttgacattcc ggtcggcatg acgaatcgtc gtacatatat aggacgcata cgtccgatta
    20161 acggacaagc gctccctagg gaccggcaga ggaggcgtca tgccgtacta ccgggtggtc
    20221 gggcaggtgc cgcgcaagcg ccacgtgcag ttccgcgcgc ccgacggcgg gctgtacaag
    20281 gaggagctca tgggagagga gggcttctcc tccgactcct cgctgctcta ccaccgtcac
    20341 gcgccgaccg ccatcgtcaa ggccgaggcc gtggacgcgg gagcgcccgg cctcacgccc
    20401 aacctgccgc tgtccccgcg ccatttccgc acccgggacc tgacgcccga cggcgacctg
    20461 gtctccggtc ggatgccgct cgcgggcaac tccgacgtcc gcatctcgta cgccgcgacg
    20521 gacgcgccca gcgagctgta ccgcgactcg atgggcgacg agtgcgtcta catcgcgcgc
    20581 ggccgggccc ggttcgagtc ggcgtacggc gcgctggacg tggccgaggg cgactacgtc
    20641 gtcatcccga ccggggcgat ccaccggtgg gtgcccgagg gcccggtgac cgcgctggtg
    20701 atcgaggcgg ccgggcacat caggccgccc aagcgctacc tgtcccggtt cggccagttc
    20761 ctggagcacg cgccgtactg cgagcgcgac ctgcgcgcgc cggccgagcc gctgctcgtg
    20821 gacggcgagg aggtcccggt cctggtcagg acgcggggcg ggctgacccg gctgacctac
    20881 gcccaccatc ccttcgacgt ggtgggctgg gacggctgcc tctacccgta cgcgttcaac
    20941 atccaggact tcgaacccat cgtgaagcgg acccacgcgc cgccgccggt ccaccagacc
    21001 ttcgaggggc cgggcttcgt cgtctgctcg ttctgccccc ggccgctgga cttccacccg
    21061 gaggccgtgc cgatcccgta caaccaccac aacgtggact ccgacgagtt catgttctac
    21121 gtgggcggcg actacaccgc caggaagggg tcgggcatcg acgtcggctc gatctcgctc
    21181 cacccggccg gcttcacgca cggcccgcag ccgggcgcgg tggaggccgc cgtcgaggcc
    21241 gtgcgccagg gacacaccga gacgaccgag atggccgtca tgatcgacac gttccgcccg
    21301 ctcgacctcg gccaggccgc cctggcctgc gaggacaccg gctacgcgtg gacgtgggcg
    21361 cgatgagctt cgggctcggc aacctgccgt acggcgtgtt ctcccggccc ggcgagcccc
    21421 gcagggtcgg cgtccgggtc ggggaccagg tcctcgacct ggccgccgcc ctcggcgggg
    21481 acgtctacgc ggcgcccagc ctcaacccgc tgctggccct gggccgtgcg tcctggcagg
    21541 agacgcgcgc gcgggcgcga gaggcggcgg ccacgggcga ccacctgatc ccgctggcgg
    21601 aggtgacccc gcacctgccg atcgaggtgg ccgactacgt cgacttctac gcctcgttcg
    21661 agcacgcgtc gaaccttggg cggatgttcc ggccggacga cgagccgctg aagcccaact
    21721 ggcggcacct gcccgtcggc taccacgggc gggcgggcac cgtcgtcgtc tcgggaacgc
    21781 cgatcaggcg gccgtgcggg cagcggccgt cgttcggccc gtcgcgcaag ctcgacatcg
    21841 aggcggaggt cggcttcgtc gtcggggtgc cgacgcggct cggcgagcgc gccggcgcgt
    21901 tcgaggacca cgtcttcggg gtggcgctcg tcaacgactg gagcgcccgc gacatccagg
    21961 cgtgggagta cgtcccgctc ggtccgttcc tgggcaagtc gttcgccacc tcgatgtcgg
    22021 cgtggatcac gccgctcgac gccctggagg aggccagggt cgagggccgg tcgcaggagc
    22081 cggagccgct cgcctacctc cgccggcagg cgccctgggg tctcgacctc accctgcacg
    22141 tcgaactgaa cggcgagacg gtctcgacgc cgtcgttccg cgacatgtac tggacgcccg
    22201 accagatgct cgcccacctg accgtgaacg gcgcctcgct gcgcacgggc gacctgttcg
    22261 cgagcgggac ggtgtcgtcg gtcgggcagc cgggctcgct catcgagctg acctggaacg
    22321 gcgcatatcc ggtcaaactg cccggcgaga cccggagctt cctggaggac ggcgacaccg
    22381 tcacgatcag cgcgtggacc tcgcacggcg tcagcctcgg cgaggtgtcg gggaagatcc
    22441 ttccggcgac ttagcgtatt tctgtcgtca
//
