LOCUS       NZ_BMMN01000005        23688 bp    DNA     linear   CON 22-DEC-2024
DEFINITION  Microbispora bryophytorum strain CGMCC 4.7138 sequence05, whole
            genome shotgun sequence.
ACCESSION   NZ_BMMN01000005
VERSION     NZ_BMMN01000005.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Microbispora bryophytorum
  ORGANISM  Microbispora bryophytorum
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Streptosporangiaceae; Microbispora.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 486322)
  AUTHORS   Sun,Q. and Zhou,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 202X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014645855.1-RS_2024_12_22
            Annotation Date                   :: 12/22/2024 07:39:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,203
            CDSs (total)                      :: 7,136
            Genes (coding)                    :: 7,048
            CDSs (with protein)               :: 7,048
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 16 of 88
            Pseudo Genes (incomplete)         :: 78 of 88
            Pseudo Genes (internal stop)      :: 7 of 88
            Pseudo Genes (multiple problems)  :: 11 of 88
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:18:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 407879
            Orig. end                         :: 431567
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMMN01000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23688
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..23688
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23688
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:13688](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13688)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            1191..1646
                     /locus_tag="IEY80_RS17525"
                     /old_locus_tag="GCM10011574_35450"
     CDS             1191..1646
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039673.4"
                     /locus_tag="IEY80_RS17525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_35450"
                     /product="DUF6157 family protein"
                     /protein_id="WP_208762475.1"
                     /transl_table=11
                     /translation="MAEDLNYYSTLIAVADDCPVTAAEVPVARGGKPTVASLQYELISG
                     APYGLTQEDVLFETWLRRQDLPADLPAGRRAELREEFFSRSQACLRASPLPKRYGWGLL
                     FDPDGRIALCPMESEEYRRLADGASRGVRTGEGGGVRVLKAMRSRRS"
     gene            1919..2587
                     /locus_tag="IEY80_RS17530"
                     /old_locus_tag="GCM10011574_35460"
     CDS             1919..2587
                     /EC_number="3.1.-.-"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019610317.1"
                     /locus_tag="IEY80_RS17530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_35460"
                     /product="dienelactone hydrolase family protein"
                     /protein_id="WP_142575165.1"
                     /transl_table=11
                     /translation="MGEVELSVRMPVGDVVLDADVTVPRQARGAVLFAHGSGSGRHSPR
                     NRYVARELQRAGLATVLADLLTAEEERVDAVTGHLRFDIGLLADRVGALTDRLPEDEVA
                     GGLPIGLFGASTGAAAALVAAATRPGGVSAVVSRGGRPDLAGDALRSVRQPTLLIVGER
                     DTVVLDLNREAMRAITAPVRLETVPRATHLFEEPGALETVARLARDWFLHHLAGGGAST
                     "
     gene            2612..3589
                     /locus_tag="IEY80_RS17535"
                     /old_locus_tag="GCM10011574_35470"
     CDS             2612..3589
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017568996.1"
                     /locus_tag="IEY80_RS17535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_35470"
                     /product="aldo/keto reductase"
                     /protein_id="WP_142575166.1"
                     /transl_table=11
                     /translation="MEQRVLGRTGRQVGVVGLGAWQLGADWGEVSEADALATLNAAVDA
                     GTTFIDTADVYGDGRSEKVIGKLLKERTGLTVATKMGRRVQQTPDAYILDNFRAWTDRS
                     RANLDVDTLDLVQLHCPPSAVFETDEVFDALDTLVAEGRIAAYGVSVETVAEALTAIAR
                     PGVASVQIILNAFRLKPLDEVLPAAEKAGVGIIARVPLASGLLSGKYGPQTVFGEDDHR
                     NFNRQGEAFDVGETFSGVEYGVGLQAVERLRGLVPEGMTMAQFALRWIIDQPGVSVVIP
                     GARNPAQAGANVAAAQFPPLSAETHDAVRQVYDDLIRPQVHHRW"
     misc_feature    complement(3651..3668)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.07"
                     /tool="antismash"
     gene            3686..4528
                     /locus_tag="IEY80_RS17540"
                     /old_locus_tag="GCM10011574_35480"
     CDS             3686..4528
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546041.1"
                     /locus_tag="IEY80_RS17540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_35480"
                     /product="carotenoid biosynthesis protein"
                     /protein_id="WP_229689695.1"
                     /transl_table=11
                     /translation="METWETARKSAAEADETPPANAPRLAGAWPIAAGVAALVAMVAAQ
                     IATGLRPQDLRLTTAVVVLLAVSALAFAAAAHTPRRAAGAFAAAVAAGYAAEWIGTRTG
                     LPFGDYRYTDALWPRPGGVPLVVALAWGGMGLAAHAVARRMAPRGRLTPILAGALALTA
                     WDLFLDPQMLRLGLWVWAEPGPYHGVPLTNFAGWLLVSVLVMVLVDRVTGRAAANRPVS
                     GAQAAGTTGLVTLYTVMAMMETVGFAVVFRPPDPFVAAAGGLAMGAFALLAWRRAWRR"
     gene            4516..6060
                     /locus_tag="IEY80_RS17545"
                     /old_locus_tag="GCM10011574_35490"
     CDS             4516..6060
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546040.1"
                     /locus_tag="IEY80_RS17545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_35490"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_229689696.1"
                     /sec_met_domain="DAO (E-value: 5.8e-12, bitscore: 40.5,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEVIVVGGGVGGMVAALLLARDGHDVRIYERLPRLGGKLAEHRR
                     DGFTFSIGPSLLTLPGLFLDLGVPLDLVELDELCRYRFADGSTLSTCRDPERTAEAVDR
                     LAPGEGRNWRAFHRWAERCLDASTRTFFAGPPSGPVVEPPFRLAGRRPGERPVGPAGGQ
                     PSGPLPRPRLGDLLAVAPGRTLHALAGRFFRDARLRQYVDRYATYAGSNPYRAPAALGC
                     VPAIEHGDGGWYVRGGLPRLADALAAALDKAGVEIRLETEIAEIVADGERVGGVRTVLG
                     EVVRADVVIVNADAASLYGRLLPDRARLRRIARLGLSSSAFLMLAAVEGRTEGLPHHSV
                     VFSADYRREFGDIFDRRRPPEDPTVYIGCPAVTDATQAPAGAESWSMLVNVPAGDPGRW
                     PTPPEAYAELVLDRLARRGHDLSGRLRFLDLLTPADLRDRYGTWGGAVYGGAYGDPFAP
                     FRRPGNRGPRRGLYLVGGSAHPGGGLPLVAMGGRIVAALVRRDFPRSRPRPEEAGR"
     gene            6057..7565
                     /locus_tag="IEY80_RS17550"
                     /old_locus_tag="GCM10011574_35500"
     CDS             6057..7565
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546039.1"
                     /locus_tag="IEY80_RS17550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_35500"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_229689697.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2e-22, bitscore:
                     74.6, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTRTARAAGAAGAVRAAKVGRVVRVAGAVKTAGVVGAAGAVRAA
                     GRKRPGTAARVLAAAQAVAAVVVLVRLARGRRRLPPLTAPAPERSPGAGDGAPRASAGG
                     GMSRGGDGAAGGGGSVGGGMSRAGGGAAGGGGWAGGGESALRGDPAARIGRDGTPGGGD
                     PDISVVIPARDEERRIGPCLRAVLADPAVTEVIVVDDESSDGTARLAAASGATVVRGRP
                     LPDGWVGKQWALHQGLREARGEIVVTLDADTRPRPGLFGALAAALVDHDLVSAGPRFVC
                     DGLAEQALHASFLATLVYRFGPIGPPAPPPPHRVVANGQCLAFRRGAMRRADGFARIRG
                     HMTDDVALARTLAADGWRVGFLDAGGLLEVDMHESAAEVWREWGRSLPLRDVTRPAWQA
                     ADLAVVWLAAALPALRLAAGRPTRLDLTLLAVRVLLTTALRRSYARPGAGVMLSFLLDP
                     VTAVRLTQATLRPVRTWRSRAYGLGRPAVTSGARPAPPDRNAAR"
     gene            complement(7516..8130)
                     /locus_tag="IEY80_RS17555"
                     /old_locus_tag="GCM10011574_35510"
     CDS             complement(7516..8130)
                     /EC_number="2.3.1.275"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0043772 - acyl-phosphate
                     glycerol-3-phosphate acyltransferase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546038.1"
                     /locus_tag="IEY80_RS17555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_35510"
                     /product="glycerol-3-phosphate acyltransferase"
                     /protein_id="WP_229689698.1"
                     /transl_table=11
                     /translation="MTTLPPLVPMLVALIGGYLLGSIPVAVLVAGRRGVDPREVGDRNP
                     GFWNVRERLGRRAAAPVFAGDTAKGVLAGLLGLLAGGAHTTGPGVVTGPSAPAAYLAVG
                     AAMIGHAWPVFAGFRGGRSVLTFAGGVAVICPPAFVLALALLAVTFLLTRSFAIGARAG
                     VFAIPLLQLPFAPIGHIAATGALMCLIGLRFGQAALAARRT"
     gene            8087..8863
                     /locus_tag="IEY80_RS17560"
                     /old_locus_tag="GCM10011574_35520"
     CDS             8087..8863
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546037.1"
                     /locus_tag="IEY80_RS17560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_35520"
                     /product="spheroidene monooxygenase"
                     /protein_id="WP_223854210.1"
                     /transl_table=11
                     /translation="MSATSMGTSGGSVVTFHLQRYAGRGAMRHMAFDRPVLRRTGGLLF
                     WRLLGTGRGASTTLGADLRRWALLAVWRDEQAVEEFLARSPIPARWRREAIETWHVRLA
                     PTASRGRWNGAEPFAPVTGGPYGGLDGEPRSGPVAVLTRASIRPSRLPAFYRSAPAVDR
                     SLRAQEGCLASVGMGEWPVARQATFSLWRDAAAVRAFAYAGRAHREVVERVRAHDWYSE
                     ELFARFVPYASAGTWDGADPLAGPLADPYAGPLADP"
     gene            complement(8950..9999)
                     /gene="plsX"
                     /locus_tag="IEY80_RS17565"
                     /old_locus_tag="GCM10011574_35530"
     CDS             complement(8950..9999)
                     /EC_number="2.3.1.274"
                     /GO_function="GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="plsX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017592062.1"
                     /locus_tag="IEY80_RS17565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_35530"
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="WP_229689699.1"
                     /transl_table=11
                     /translation="MDPGQDAAPGAGPVPGQRIPARERDVMSRRVVVDAMGGDHGPAQI
                     VRGAVEAWREHGVPVVLVGRSGAVRGELARAGAAGEIDVAHAADVVPMTERGAGAIRMA
                     CSNLAVGFDLLRAGAGAAFVSAGSTGAVVACAVDRLGTAPAVLRPALAVALPTTAGGAT
                     VLIDAGATVDPTPEMIAQFALLGASYAQVVLGVPDPRVGLLSIGAEPGKGNRLTRRAET
                     LLRGMPLRFHGNVEGGDVLTGAVDVIVTDGFTGNVVLKNVEGTVRAALTLAAAQGVAGS
                     AELGRVARRYDPETHGGAALLGLTRTVVVAHGSSRAATIARACVVARDLAEGEVVARLG
                     DRLAIRPVS"
     gene            complement(10001..10930)
                     /locus_tag="IEY80_RS17570"
                     /old_locus_tag="GCM10011574_35540"
     CDS             complement(10001..10930)
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890490.1"
                     /locus_tag="IEY80_RS17570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_35540"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_142575169.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.3e-97, bitscore:
                     321.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1e-68,
                     bitscore: 226.5, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTLSTPSRAPAATLTAGYERCRRLHASYGRSYYLATRLLPAWKR
                     PHVHALYGFARYADEIVDSLAMTGDRAAALERLSSRLAAALDGERVHDPVLPAFTHTVR
                     AFGIDQADVRAFLASMRADLTVDRYATYDDLLGYMEGSAAVIGTMMLPVLEALPGEDAR
                     AREPARQLGLAFQLTNFIRDVREDLARGRVYLPLSDLEKFGVTEADLAAPYATPAVREL
                     VAYECDRARDHYRRARDGIALLAPSSRPCITAAYELYGGILDEVEAAGHDVLVRRAAVP
                     RRRRLAIFVRHLLAARAAVRAERRVGVA"
     gene            complement(10927..12438)
                     /locus_tag="IEY80_RS17575"
                     /old_locus_tag="GCM10011574_35550"
     CDS             complement(10927..12438)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546035.1"
                     /locus_tag="IEY80_RS17575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_35550"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_142575170.1"
                     /sec_met_domain="DAO (E-value: 1.6e-15, bitscore: 52.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAGGPVVVIGAGLGGLSAAMRLAGAGREVTVVEASDVPGGCCGT
                     ATLGSHRFDTGPSVLTMPGVLADTFAAAGQDMERWLPLRRLDPYYRLTFHDGSRLDVVA
                     GADAMAEQVRELSGPEEARRYQRFRRLLGEMFEAEWGAFIDRDMTRLRALARPYALARL
                     AALGGFRRLDGLVRRHLTDERLIRAHTFQALYVGLSPRRALGVYAVIAHMDTVGGVYFP
                     REGGMHAVPRAMAAAAEKAGAVFRYGVRATRIETDGAGVVAVRLATGERLAARHAVVAC
                     DLVRAQGRRGGDGLLPEEAADWRLRRPRFSPSCLVAHFALDRRPEGQAHHTLHFGREWE
                     STFAALEAGRPQSDPSLLVTCPVNHGPDNHGPHDHGPGDGGPAVLSVLEPTANTRGGAD
                     WTALTPRLLDRMLSRLADLGYGDLSATPRLVLDPPAWRRRGHSAGTPFALDARFTQTAW
                     FRPSGAARRVPGLHFAGMYTAPGVGVPPVLISGRLAAERILESAP"
     gene            complement(12438..13688)
                     /locus_tag="IEY80_RS17580"
                     /old_locus_tag="GCM10011574_35560"
     CDS             complement(12438..13688)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.5"
                     /locus_tag="IEY80_RS17580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_35560"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_167748453.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.6e-50, bitscore:
                     165.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTLTRETGGVRDDPREPFDRHLSGLFDHALDELLRRELSRLSFL
                     GADDREVLRRHLADFVARGGRRLRPAFVYWGHRACGGSPDDLGAVLAAGCSIELLHACA
                     LILDDVMDESPLRRGRTTAHLALAERHRELGWAGSSQRFGESAAILLGVLAFTWADSAL
                     LADRRRLADALEVFTQLRVELIAGQYLDLTCAARGGGDHREALLISTYKSGRYTVERPL
                     HLGHAIAGGDPGLRRVLSAYALPLGEAFQLRDDVLGVFGDPARTGKPAGADLLQGKRTY
                     LLTLARERADGPGAALLDALPGTGEAQPDRLAAAREVIVATGALEAVERRIRDLTESAG
                     EALSGADMPADARTALLGLALRLAQPHSAADPHPAADPHPAARPDHAARPGQAGNAASP
                     GPAPPAGSAEPAAGGAA"
     gene            13865..14866
                     /locus_tag="IEY80_RS17585"
                     /old_locus_tag="GCM10011574_35570"
     CDS             13865..14866
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012888349.1"
                     /locus_tag="IEY80_RS17585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_35570"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_229689700.1"
                     /transl_table=11
                     /translation="MTREGGSGAGEHAAAEEEPGYGIGAVSRRLGVPASTLRTWNLRYG
                     IGPSRRSPGGHRRYDDADLRRLEEMNRLIRAGMPPADAARQALRLRPAPGERAASAPAR
                     EGAASPESPGRPEPTVPSASAVRPAADPGLLSAAMLARAVTVLDTATVDAGLDAALAAH
                     GVMWTWERLVLPVFAAVTRRQQDTGAGIDVEHLFSDRLQAALARFSARVPSPVHPRPVL
                     LAAAEEEQHALPIHALAAALGVLGVETRVLGARTPYTTLADAMRRLGPAAVFVWSQLRE
                     TGDPTPLAGLPGLRPACRVVVGGPGWRDGLPTHVIRVNTFRDALSAVMTTLR"
     misc_feature    14951..14962
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.31"
                     /tool="antismash"
     gene            14990..15511
                     /locus_tag="IEY80_RS17590"
                     /old_locus_tag="GCM10011574_35580"
     CDS             14990..15511
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012888348.1"
                     /locus_tag="IEY80_RS17590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_35580"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_142575173.1"
                     /transl_table=11
                     /translation="MEETLEFRLAAGDTGALGECYRVHSPAVRSYLRKLVPPQDVEDVM
                     QVVFTEVWRFRHRFDPGRSLPAWLFGIARNRAVDHLRARAPATVPLEAVPDPAGRDGRL
                     DGDQFADRDRIRRALASLPQVQRQAIELAYYGDLTQREIAERLRVPLGTVKARTARGLH
                     RLSTLLRPAA"
     gene            15577..16074
                     /locus_tag="IEY80_RS17595"
                     /old_locus_tag="GCM10011574_35590"
     CDS             15577..16074
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015060.5"
                     /locus_tag="IEY80_RS17595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_35590"
                     /product="TspO/MBR family protein"
                     /protein_id="WP_142575174.1"
                     /transl_table=11
                     /translation="MRRTSKKTLVRTALAVTATAAVGGLSTDARSGWCARLRKPSWQPP
                     PKAFGLVWTPLYATIAYASARALSHGDDGSRPALRRALAANLALNAAWPPLFFKARNPR
                     LALAEILALNVSNALLTRRLLRQDRTAGLLLLPYAGWTVFATALNAAIARHNPEAQHNP
                     KV"
     gene            complement(16165..17136)
                     /locus_tag="IEY80_RS17600"
                     /old_locus_tag="GCM10011574_35600"
     CDS             complement(16165..17136)
                     /NRPS_PKS="Domain: PKS_KR (31-167). E-value: 5.8e-08.
                     Score: 24.8. Matches aSDomain:
                     nrpspksdomains_IEY80_RS17600_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024950.5"
                     /locus_tag="IEY80_RS17600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_35600"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_142575175.1"
                     /transl_table=11
                     /translation="MTMRELITTPFTSSSTADEVLRGVDLTGVRAIVTGGSSGIGTETA
                     RALTSAGAEVTLAVRNTTAGDAVAETIAKSTGQIRPRVVRLDLADRSTVARFVDAWNGP
                     LHLLINNAGVVTGGLERTREGWELQFATNHLGHFALATGLHDALTLGAADGDGARIVSV
                     SSTAHMRSGIDFDDLHFERRSYDPQIAYAQSKTANSLFAVEATRLWASDGIIANAVNPG
                     GVATGLQRNFTAQQKASLDAAEAAGIFTYKTVEQGAATSIVAAVAPEFAHFGGHYLDDS
                     QEAYTVPDDADLAQHPHGVKEWALDPTAAKRLWTVSTDLLRV"
     aSDomain        complement(16636..17043)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEY80_RS17600_PKS_KR.1"
                     /evalue="5.80E-08"
                     /label="IEY80_RS17600_PKS_KR.1"
                     /locus_tag="IEY80_RS17600"
                     /protein_end="167"
                     /protein_start="31"
                     /score="24.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="IVTGGSSGIGTETARALTSAGAEVTLAVRNTTAGDAVAETIAKST
                     GQIRPRVVRLDLADRSTVARFVDAWNGPLHLLINNAGVVTGGLERTREGWELQFATNHL
                     GHFALATGLHDALTLGAADGDGARIVSVSSTA"
     CDS_motif       complement(16978..17043)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEY80_RS17600_0001"
                     /evalue="4.40E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="IEY80_RS17600"
                     /protein_end="53"
                     /protein_start="31"
                     /score="16.2"
                     /tool="antismash"
                     /translation="IVTGGSSGIGTETARALTSAGA"
     misc_feature    complement(17190..17206)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.06"
                     /tool="antismash"
     gene            17200..17772
                     /locus_tag="IEY80_RS17605"
                     /old_locus_tag="GCM10011574_35610"
     CDS             17200..17772
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009073940.1"
                     /locus_tag="IEY80_RS17605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_35610"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_142575176.1"
                     /transl_table=11
                     /translation="MSSPEVGHPPSTVADTDRRITVLDSAMVTFARFGYRKTSMEEVAR
                     AAGISRPGLYFLFSSKETLFRAAVTQALNRDITAVEHVLADTGRPLSERLVEAFDQWAG
                     RYIGPLASDVAMVIEDNPDLLGEIIKTPRRRFEELITDAVAITSGREAAPLVAQTMISA
                     SIGIKHQVASREVYLERLEVAIDLLLR"
     gene            complement(17880..18386)
                     /locus_tag="IEY80_RS17610"
                     /old_locus_tag="GCM10011574_35620"
     CDS             complement(17880..18386)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017579079.1"
                     /locus_tag="IEY80_RS17610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_35620"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_142575177.1"
                     /transl_table=11
                     /translation="MSGTRWLDEEEQHTWRSYLRTSQLLQEALERQLQRDSGMPHAYYM
                     ILVVLSESPGRTMTMTELSAILQYSVSRLSHAVSRLEEKSWVRRLKRPEDRRTTVAELT
                     DEGFAALVEAAPGHVEEVRRVLFDPLTPGQVRQFGEILDTILSAFEYHRAAEAEGSPAL
                     DAAAQ"
     misc_feature    18416..18425
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.04"
                     /tool="antismash"
     gene            18473..20773
                     /locus_tag="IEY80_RS17615"
                     /old_locus_tag="GCM10011574_35630"
     CDS             18473..20773
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012891915.1"
                     /locus_tag="IEY80_RS17615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_35630"
                     /product="phosphoketolase"
                     /protein_id="WP_142575178.1"
                     /transl_table=11
                     /translation="MDAYGNIDAYWRAANYLSVGQIYLMDNPLLTEPLSPEHVKPRLLG
                     HWGTTPGLNFCFAHLNRIIRERGQDMIYIAGPGHGGPAAVAHAWLEGTYTERYPHVTQD
                     AEGMRRLFRQFSFPGGIPSHVAPETPGSIHEGGELGYALSHAYGAAFDNPSLVVACVVG
                     DGEAETGPLATGWHSNKFLNRDTDGVVLPILHLNGYKIANPAVLARIPEDELVKLFEGY
                     GYRPHIVAGQEPAEMHELMAETLDTVFEQMADRGPLPMIILRTPKGWTGPREVDGLPVE
                     GTWRAHQVPLTDVRNRPDRLEALEEWMRSYRPEELFDVDGRPVEIITRTVPDGPLRMSA
                     SPHANGGELLRPLVLPDFRDYAVEVKAPASASSEPTRVLGAFLRDVIAANPANFRLLGP
                     DETASNRLSAVFEATDKEWEAALLPTDENLGPRGRVMEVLSEHQCQGWLEGYLLTGRHG
                     LFNCYEAFIHIVDAMFNQHAKWLESSRKIPWRRPVASLNYLLSSHVWRQDHNGFSHQDP
                     GFLDVVLNKKAEVVRVYLPPDANTLLSVADHCLRSRDYVNVVVAGKQPVLDLMSMDEAV
                     VHCTRGLGILEWASTDAGAEPDVVLGCAGDVPTLETLAAAALLREHLPELRIRVINVVD
                     LMRLQPASEHPHGMSDAEFDALFTTDKPIIFNFHGYPWLIHRLTYRRTGHDNLHVRGYK
                     EEGTTTTPFDMAMLNDIDRFHLVMDVIDRVPGLGGRTAHLRQRMADARLRARAYTREFG
                     EDPAEIRDWTWPY"
     gene            20967..22943
                     /gene="thrS"
                     /locus_tag="IEY80_RS17620"
                     /old_locus_tag="GCM10011574_35640"
     CDS             20967..22943
                     /EC_number="6.1.1.3"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thrS"
                     /gene_functions="other (smcogs) SMCOG1162: threonyl-tRNA
                     synthetase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011292531.1"
                     /locus_tag="IEY80_RS17620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_35640"
                     /product="threonine--tRNA ligase"
                     /protein_id="WP_142575179.1"
                     /transl_table=11
                     /translation="MSAALEIRITLAGAERVVAAGTTAGEALGADGRSVIAARIDGELR
                     DLATEVAEGDVVEPVAIDSPDGRAILRHSTAHVMAQAVQEIFPDAKLGIGPPVENGFYY
                     DFDVREPFTPDDLKRIEKRMREIVKQGQTFRRRPIGDDEARAELAAEPYKLELIGLKGG
                     AADAADGANVEVGGGQLTIYDNLDAKSGELCWKDLCRGPHLPSTRVIPAFKLMRSGGAY
                     WRGSEKNPQLQRIYGTAWETREKQDEYLKLLEEAEKRDHRKLGAELDLFSFPDELGSGL
                     PVFHPKGGVIRRVMEDYSRRRHEEAGYSFVNTPHITKDNLYKISGHLDWYADGMFPPME
                     LEGARYYLKPMNCPMHNLIFGARGRSYRELPLRLFEFGTVYRYEKSGVVHGLTRVRGLT
                     QDDAHIYCTREQMRDELTSLLRFVLDLLRDYGLEDFYLELSTKDPEKFVGSDETWEEAT
                     QTLREVAESEKLELVLDPGGAAFYGPKISVQARDAIGRSWQMSTIQLDFNLPERFGLEY
                     QASDGTRQQPVMIHRALFGSIERFFGVLVEHYAGAFPAWLAPVQVVGIPIADAHAPYLQ
                     DVAKRLREQGIRIEVDESDDRMQKKIRNAQKAKVPYMLLAGDDDIAAGAVSFRYRNGEQ
                     KNGVPIDQAIDEIVDAVRRRVQV"
     misc_feature    complement(23423..23438)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.59"
                     /tool="antismash"
ORIGIN
        1 gctgcgctac ggcgcccggc aggacgacac gtcggccgcc gggcacgcct actacggctc
       61 ggtcgacgcc agcccgctgt tcgtcatcct gcttggcgag ctgcgccgct ggggtctgca
      121 ccggacggcg gtggagcggc tgcttccgca cgcggacgcg gcgctggagt ggatcgagcg
      181 gtacggcatg cgtgacgggt tcctgtggta ccagcggaag accgaccagg gtctgctcaa
      241 ccagggctgg aaggactcct tcgacggcat caacttcgcc gacggcacga tcgcccgggc
      301 gcccatcgcc ctggccgagg tgcagggata cgtctacgcc gcctgcatcg cccgccacta
      361 cttcgcccag gaggagggcg acaccgagac cgagcggcac taccgggacc gggccgcgga
      421 ggtgcgcgcc cggttcaacg aacggttctg gctgcccgac cgcggctact tcgccgtcgg
      481 gctcgaccac gagggccgcc cgatcgacgc cctcgcctcc aacatgggcc actgcctgtg
      541 gtcggggatc gtcgaccgcg acaaggcccc ggccgtggcc gagcacctgc tgtcgccccg
      601 gatgttcacc ggcttcggca tccgcaccct cgcctccgac atgggcgcct acaacccgat
      661 gagctatcac aacgggtccg tctggccgca cgacagcgcg ctcgccgcgg ccggcctcat
      721 gcgctacgga ttcgtggagg aggcccagcg cgtcgccacc ggcctgctcg acgccgcccg
      781 cgccttcggc ggccggcttc ccgagctgtt ctgcgggttc gaccgcgggg agttccacat
      841 gccggtgccg tacccgacct cgtgctcgcc gcaggcctgg gcctcggcca ccccgatcca
      901 gctcgtacgg ctcctgctcc gcgtggaccc gtgggtgccg catggcaagg tgtggatcgc
      961 gccggtgctg cccaaggggt tcgggcagct gagcatctgc ggcttcccga tcgcgggcac
     1021 ccgggtcgat ctggaggcat gggaggacag cgcggaggtg cacgtgagcg gcctgcccga
     1081 ggacgtgggc ctcatctgtg agacccgccc gaccgccgcc ttcggcaagc gttccgcggg
     1141 cccgcccgta gcggggtgag ccgtccggtc tcccgcggca tagtgaagag atggccgagg
     1201 acctgaacta ctactcgacg ctcatcgcgg tcgccgacga ctgcccggtg accgccgcgg
     1261 aggtgcccgt ggcccggggc ggcaagccca ccgtcgcctc cctccagtac gagctgatct
     1321 ccggcgcgcc gtacggtctg acgcaggagg acgtgctgtt cgagacctgg ctgcgccgcc
     1381 aggacctgcc ggcggacctg ccggccgggc ggcgcgcgga gctcagggag gagttcttct
     1441 cccgttccca ggcgtgcctg agggcgtccc cgctgccgaa gaggtacggc tgggggctgc
     1501 tgttcgaccc ggacggccgc atcgcgctgt gtcccatgga gtcggaggag taccggcgcc
     1561 tggcggacgg cgcgtcccgc ggcgtacgga ccggggaggg cggcggcgtg cgggtgctca
     1621 aggcgatgcg ctcacgtcgc tcctgacgcg gcgatgcacg cgtcactcct ggcgcggtga
     1681 tgctcgtcgc gctcctgaca tcgcctgaaa cccgccgcct gtcacccgca gcctgtcacc
     1741 cgccgcctga catcaccgcc gccgacgcct cttccgcagg cggaggccac gtcgtccccg
     1801 gtttgccccg gcaggccggg ggtaggcccc ccgattgtcc agtgccgtcc tggttgtgcg
     1861 gcgtcgtcct ggtcgtccag cgccgctgag ccgggcgcgg ccggaagggg cgggcgccat
     1921 gggcgaggtc gaactcagcg tgcggatgcc ggtcggcgat gttgtgctcg acgccgacgt
     1981 gacggttccc cggcaggccc ggggggcggt gctgttcgcc cacggcagcg gcagcggccg
     2041 gcacagcccg cgcaatcgat acgtcgccag ggagctgcag cgggccgggc tggcaacggt
     2101 cctggccgac ctgctcacgg cggaggaaga gcgcgtcgac gcggtcaccg gccacctgcg
     2161 cttcgacatc ggcctgctcg ccgaccgggt gggcgcgctg accgaccggc tgcccgagga
     2221 cgaggtcgcc ggaggtctgc ccatcggcct gttcggcgcg agcacgggcg ccgccgccgc
     2281 actcgtcgcc gcggcgacgc ggcccggcgg cgtcagcgcg gtggtgtcca ggggcggcag
     2341 gcccgacctc gccggggacg cgctccgctc ggtgcgccag ccgacgctgc tgatcgtggg
     2401 ggagcgcgac accgtcgtcc tcgacctcaa cagggaggcg atgcgggcga tcaccgcgcc
     2461 ggtccggctg gagacggtgc cccgcgccac gcatctgttc gaggagcccg gggcactgga
     2521 gacggtcgcg cggctcgccc gcgactggtt cctgcaccac ctcgcgggtg gaggggcctc
     2581 cacctgagcc gccccgctac gatctgacct catggaacag cgcgttttgg gcaggacagg
     2641 caggcaggtc ggcgtcgtcg ggctgggggc gtggcagctc ggggccgact ggggcgaggt
     2701 gagcgaggcc gacgcgttgg ccacgctcaa cgccgcggtc gacgccggga ccactttcat
     2761 cgacacggcc gacgtgtacg gcgacggccg cagtgagaag gtcatcggga agctgctcaa
     2821 ggagcggacc ggcctgaccg tggccacgaa gatgggccgc agggtgcagc agacccccga
     2881 tgcctacatt ctggacaact tccgcgcctg gaccgaccgc tcccgcgcca acctggacgt
     2941 cgacacgctc gacctggtgc agctccactg cccgccgagc gccgtcttcg agaccgacga
     3001 ggtcttcgac gcgctcgaca cgctggtcgc cgagggccgc atcgcggcgt acggcgtgag
     3061 cgtggagacg gtggccgagg cgctgaccgc gatcgcgcgc cccggcgtgg ccagcgtgca
     3121 gatcatcctc aacgccttcc ggctgaagcc gctggacgag gtcctgccgg ccgcggagaa
     3181 ggccggagtc ggcatcatcg cccgggtccc gctggcgagc ggcctgctgt cgggcaagta
     3241 cggcccgcag acggtcttcg gcgaggacga ccaccgcaac ttcaaccgcc agggcgaggc
     3301 gttcgacgtc ggcgagacct tctccggcgt cgagtacggc gtgggcctcc aggcggtcga
     3361 gcggctgcgc ggcctcgtgc cggagggcat gacgatggcg cagttcgcgc tgcgctggat
     3421 catcgaccag cccggggtca gcgtcgtgat ccccggagcc cgcaaccccg cgcaggccgg
     3481 ggccaacgtg gcggcggcgc agttcccgcc gctgtcggcc gagacccacg acgcggtccg
     3541 ccaggtctac gacgacctga tccgcccgca ggtgcaccac cgctggtgat cgccgggccg
     3601 gtgcgtacgg cggggcgacc ccgccggccg cacccgcgtg aggcggagcg catccgatca
     3661 gggggatgcg ctcgaatgac cctacgtgga gacctgggag accgcacgga agagcgcggc
     3721 cgaggctgac gaaacaccgc cggcgaacgc gccccgcctg gcaggcgcgt ggccgatcgc
     3781 ggccggcgtg gccgcgctgg tcgcgatggt ggccgcccag atcgcgacgg gactgcggcc
     3841 ccaggatctg cgcctcacca ccgccgtcgt ggttctgctc gcggtgagcg cactcgcctt
     3901 cgcggcggcg gcgcacaccc cgcgcagggc ggcgggcgcg ttcgcggcgg cggtggcggc
     3961 cggttacgcc gccgagtgga tcggcacgag gacgggcctg cccttcggcg actaccgcta
     4021 caccgacgcc ttgtggccgc ggcccggcgg cgttccgctg gtcgtcgccc tcgcctgggg
     4081 cggcatgggc ctggccgccc acgccgtcgc ccgccgtatg gcgccgcgcg ggcggctgac
     4141 gccgatcctc gccggagctt tggcgctcac cgcgtgggac ctgttcctcg acccccagat
     4201 gctcaggctc ggactgtggg tctgggcgga gccggggccg taccacggtg tgccgctcac
     4261 caacttcgcc ggctggctgc tggtctctgt cctggtcatg gtgcttgtcg accgcgtcac
     4321 gggccgcgcc gccgcgaacc ggcccgtgag cggcgcccaa gcggcgggga cgaccgggct
     4381 cgtcacgctc tacacggtca tggcgatgat ggagaccgtc ggcttcgccg tggtcttccg
     4441 gccgcccgat ccgttcgtgg ccgccgccgg agggctcgcg atgggcgcct tcgccctgct
     4501 cgcctggagg cgcgcgtggc ggaggtgatc gtggtcgggg gtggcgtcgg cggcatggtg
     4561 gccgccctgc tgctcgcgcg ggacgggcac gacgtgcgga tctacgagcg gctgccccgg
     4621 cttggcggca agctggccga acacaggcgg gacgggttca cgttctcgat cggcccttcg
     4681 ctgctcacgc tgcccggcct cttcctggac ctcggcgtgc cgctcgacct ggtcgaactc
     4741 gacgagctgt gccggtatcg gttcgcggac ggctcgacgc tgtccacctg ccgcgacccg
     4801 gagcgtacgg cagaggcggt ggaccggctc gcgccgggcg agggccgcaa ctggcgggcc
     4861 ttccaccgct gggccgagcg ctgcctggac gcctccacgc gcaccttctt cgcgggaccg
     4921 ccgtccgggc ccgtcgtcga gccgccgttc cggctcgcgg gccggcggcc cggcgaacgg
     4981 ccggtcggac cggcgggcgg gcagccgagc ggccctctcc cgcgtccccg gctgggcgac
     5041 ctgctcgcgg tcgcgccggg ccgcaccctg catgctctgg cgggccgatt cttccgggac
     5101 gcccgcctgc gccagtacgt cgaccgctat gccacctacg ccgggtcgaa cccctaccgg
     5161 gcgcccgccg ccctcggctg cgtccccgcc atcgagcacg gtgacggcgg atggtacgtg
     5221 cggggcgggc tgccccgcct cgccgacgcg ctggccgctg cgctggacaa ggcgggcgtc
     5281 gagatccgtc tggagaccga gatcgccgag atcgtcgccg acggcgagcg ggtcggcggc
     5341 gtccgcacgg tcctcggcga ggtggtcagg gccgacgtcg tgatcgtcaa cgccgacgcg
     5401 gcctccctct acgggcggct cctgcccgac cgcgcgcggc tgcgccggat cgcccggctg
     5461 ggcctgtcgt cgtccgcctt cctgatgctc gccgccgtgg aggggcgaac cgagggcctg
     5521 ccgcatcact cggtcgtgtt ctccgccgac taccggcgcg agttcggcga catcttcgac
     5581 cggcggcggc cgccggagga ccccacggtc tacatcggct gcccggcggt gaccgacgcc
     5641 acccaggctc ccgccggcgc ggagagctgg agcatgctgg tgaacgtccc cgcaggcgac
     5701 cccgggcgct ggccgacgcc gcccgaggcg tacgcggagc tggtcctcga ccggctggcc
     5761 cgccgggggc acgacctgtc cggacggctg cgcttcctcg acctgctgac cccggccgac
     5821 ctgcgcgacc ggtacggcac ctggggcggg gcggtctacg gcggcgcgta cggcgacccg
     5881 ttcgccccct tccgccgtcc cggcaaccgg gggccgcggc gcgggctgta cctcgtcggc
     5941 gggtccgcgc atccgggagg tgggctgccg ctggtggcga tgggcgggcg catcgtggcc
     6001 gcgctggtgc gcagggactt cccccgctcc aggccgcggc cggaggaggc gggacggtga
     6061 cgaccaggac ggccagggcg gccggggcgg ccggggcggt cagggcggcc aaggtgggca
     6121 gggtggtcag ggtggccggg gcggtgaaga cggctggggt tgtgggggcg gccggggcgg
     6181 tcagggcggc cgggcgcaag cggcccggga ccgccgcccg ggtgctcgcc gcggcccagg
     6241 ccgtcgccgc ggtcgtcgtg ctggtgcggc tcgcccgagg ccgccggcgc ctccccccgc
     6301 tcaccgcgcc cgcgcccgaa aggtcccccg gcgccggtga cggggcgccg cgggcgtccg
     6361 ccggtggggg gatgtcgcgg ggtggtgatg gcgcggccgg aggcggtggg tcggtcggag
     6421 gcgggatgtc gcgggctggt ggcggcgcgg ccggaggcgg tgggtgggcc ggaggcggcg
     6481 agtcagctct taggggcgac ccggcggcgc ggatcggccg ggacggaaca cccggtgggg
     6541 gagatccgga catctcggtg gtcatcccgg cgagggacga ggaacggcgg atcggcccct
     6601 gcctgcgggc ggtgctggcc gatcccgccg tcaccgaggt gatcgtggta gacgacgagt
     6661 cctcggacgg caccgcccgg ctggccgccg ccagcggggc gacggtggtg cgcggacgcc
     6721 cgctgccgga cggctgggtg ggcaagcagt gggcgctgca ccaggggctg cgggaggcgc
     6781 gcggcgagat cgtggtcacc ctggacgccg acacccggcc ccggcccggc ctgttcggcg
     6841 cgctcgccgc cgccctcgtg gaccacgacc tggtcagcgc tggcccgcgt ttcgtctgcg
     6901 acggcctcgc cgagcaggcg ctgcacgcgt cgttcctcgc cacgctggtc taccggttcg
     6961 gccccatcgg gcccccggcc ccgccgccgc cccaccgggt ggtggccaac ggccagtgcc
     7021 tggccttccg ccggggggcg atgcggcggg ccgacggctt cgcccggata cgcggccaca
     7081 tgaccgacga cgtcgccctc gccaggaccc tggccgccga cggctggagg gtcggcttcc
     7141 tcgacgcggg gggcctgctg gaggtcgaca tgcacgagtc ggcggccgag gtgtggcggg
     7201 agtgggggcg ttcgctgccg ctgcgcgacg tcacccgccc cgcctggcag gcggccgatc
     7261 tcgccgtcgt ctggctcgcc gccgcgttgc cggcgctccg cctggccgcc gggcggccga
     7321 cccggctcga cctgacgctg ctcgccgtac gggtgctgct caccaccgcg ctgcggcgca
     7381 gctacgcccg gccgggcgcg ggcgtgatgc tgtcgttcct gctcgacccg gtcacggccg
     7441 tacggctgac gcaggcgacg ctgcggcccg tcaggacctg gcggagccgc gcctacggcc
     7501 tcggccgccc agccgtcacg tccggcgcgc ggccagcgcc gcctgaccga aacgcagccc
     7561 gatgaggcac atcagcgcgc cggtcgcggc gatgtggccg atcggcgcga acggcagttg
     7621 cagcagcggg atcgcgaaga ccccggccct ggccccgatc gcgaacgacc gcgtgagcag
     7681 gaacgtcacc gccagcaggg cgagcgcgag cacgaacgcg ggcgggcaga tcaccgcgac
     7741 gccgccggcg aaggtcagca ccgaccgccc gccgcggaac ccggcgaaga cgggccaggc
     7801 gtgcccgatc atcgcggccc ccacagccag gtatgcggcc ggggcgctcg ggccggtgac
     7861 cactcccggc ccggtcgtgt gcgcgccccc ggccagcagc ccgagcagcc cggcgagcac
     7921 gcccttggcc gtgtccccgg cgaagaccgg cgcggcggcc cggcggccga gccgttcgcg
     7981 cacgttccag aagccggggt tgcggtcgcc cacctcccgg ggatcgacgc cccgacgccc
     8041 cgcgaccagc accgccaccg ggatcgagcc gagaaggtag ccgccgatga gcgccaccag
     8101 catggggacg agcggcggga gcgtcgtcac gttccacctc cagagatacg ccggccgggg
     8161 ggcgatgcgg cacatggcct tcgaccgtcc ggtgctgcgc cgcaccgggg gcctgctgtt
     8221 ctggcggctg ctgggcacgg gccggggggc gtcgacgacc ctcggcgccg acctgcgccg
     8281 ctgggcgctg ctcgccgtct ggcgggacga gcaggcggtc gaagagttcc tggcacgctc
     8341 gccgatcccc gcgaggtggc ggcgcgaggc gatcgagacc tggcacgtgc ggctcgcgcc
     8401 gaccgcctcg cgcgggcgct ggaacggcgc agagccgttc gcccccgtga ccggcggccc
     8461 gtacggcggc ctggacggcg agccgcgcag cggtccggtg gcggtgctga cccgggcgtc
     8521 gatccggccg tcgcgactgc cggcgttcta ccggtccgca cccgccgtcg accggtcgct
     8581 gcgggcccag gagggctgcc tcgcctccgt cgggatgggg gagtggccgg tggccaggca
     8641 ggcgaccttc tcgctgtggc gggacgccgc cgccgtacga gcgttcgcct acgccgggcg
     8701 ggcgcaccgc gaggtcgtcg aacgggtccg cgcccacgac tggtactcgg aggagttgtt
     8761 cgcccggttc gtcccctacg ccagcgcggg cacctgggac ggcgccgacc ctctcgccgg
     8821 tcctctcgcc gacccctacg ccggtcccct cgccgatccc tgagcagtcc ggcgggccgc
     8881 tcgggcgtcc tcgtgacccg aaacgcgagc cggaacgcga gccggggccg ggcccagcgg
     8941 tgtgggaggt cacgacacgg ggcggatggc aagacggtcg ccgagacggg ccacgacctc
     9001 gccctcggcc aggtcgcgcg ccaccacgca ggccctggcg atggtcgctg cccgggagga
     9061 gccgtgcgcc acgacgacgg tgcgggtgag cccgagcagg gccgcgccgc cgtgcgtctc
     9121 ggggtcgtaa cggcgcgcca cccggccgag ctcggcggac ccggccacgc cctgcgccgc
     9181 cgcgagggtg agcgcggcgc gcacggtccc ctccacgttc ttcagcacga cgttgccggt
     9241 gaagccgtcg gtgacgatga cgtcgacggc cccggtgagc acgtcgccgc cctcgacgtt
     9301 gccgtggaac cgcagcggca tgccgcgcag cagggtctcg gcgcggcggg tcagccggtt
     9361 gcccttgccg ggctccgcgc cgatcgacag caacccgacg cgggggtcgg gcacgcccag
     9421 cacgacctgc gcgtacgacg ccccgagcag cgcgaactgg gcgatcatct cgggcgtcgg
     9481 gtccacggtc gccccggcgt cgatcaatac ggtggccccg cccgccgtcg tcggcagcgc
     9541 cacggccagt gcggggcgca gcacggcggg cgcggtgccc agccggtcga ccgcgcaggc
     9601 gaccacggcc ccggtggacc ccgccgacac gaaggccgcg cccgctccgg cccgcaggag
     9661 atcgaagccg acggccaggt tggagcaggc catgcggatc gcgcccgcgc cccgctcggt
     9721 catcggcacg acgtcggcgg cgtgcgcgac gtcgatctcg cccgccgccc cggcgcgggc
     9781 cagttctccg cgcacggctc cggaccggcc gacgagaacc accggcacgc cgtgctcccg
     9841 ccacgcctcg accgccccgc gcacgatctg cgcgggcccg tggtctccgc ccatggcgtc
     9901 caccacgacc cgccgggaca tcacgtcccg ctcgcgggcg ggaatgcgct gcccggggac
     9961 cggaccggcg ccgggcgcgg cgtcctgtcc gggatccacg tcaggccacc cccacccggc
    10021 gctcggcccg cacggcggca cgcgcggcga gcaggtgccg gacgaagatc gcgagccggc
    10081 gccgtcgggg caccgcggcc cgcctcacca gcacgtcgtg cccggccgcc tcgacctcgt
    10141 ccaggatgcc gccgtacagc tcgtacgcgg cggtgatgca cggccgggac gacggcgcga
    10201 gcagcgcgat cccgtcgcgg gcccgccggt agtggtcgcg ggcgcggtcg cactcgtagg
    10261 ccaccagctc ccgcacggcc ggcgtggcgt acggcgcggc caggtcggcc tcggtcacgc
    10321 cgaacttctc gaggtccgac agcggcaggt agacgcggcc ccgcgccagg tcctcccgga
    10381 cgtcgcggat gaagttcgtg agctggaagg ccagcccgag ctggcgggcg ggctcgcggg
    10441 cccgcgcatc ctcgcccggc agtgcctcca gcaccggcag catcatcgtc ccgatgaccg
    10501 ccgccgatcc ctccatgtat cccagcaggt cgtcgtaggt cgcgtaccgg tccacggtca
    10561 ggtcggcgcg catggacgcg agaaacgccc gcacgtcggc ctggtcgatc ccgaacgccc
    10621 gcaccgtgtg cgtgaacgcg gggagcaccg gatcgtggac gcgctccccg tcgagcgcgg
    10681 cggcgagccg ggaggacagg cgctccagcg ccgcggcgcg gtcgccggtc atcgcgagcg
    10741 agtccacgat ctcgtcggcg tagcgggcga agccgtacaa cgcgtggacg tgcggtcgtt
    10801 tccacgcggg cagcaggcgg gtggccaggt agtaggagcg gccgtagctc gcgtgcaacc
    10861 tgcggcaccg ctcgtagccg gccgtcagcg tcgcggccgg tgcccgggat ggcgtgctca
    10921 gcgtgctcat ggggcgctct ccaggatgcg ttcggcggcc agacggccgg agatcagcac
    10981 gggcggcacc ccgaccccgg gtgccgtgta catgccggcg aagtgaagtc cggggacccg
    11041 cctggccgcg ccggacgggc ggaaccacgc ggtctgggtg aaccgggcgt cgagtgcgaa
    11101 gggcgtgccg gccgagtggc cgcgccgccg ccaggcgggg ggatcgagca ccagccgggg
    11161 cgtggcggac aggtcgccgt atccgaggtc ggcgagccgg ctcagcatgc ggtccaggag
    11221 gcggggggtt agggcggtcc agtcggcgcc gccccgcgtg ttcgcggtgg gttccagcac
    11281 gctgagcacg gcggggccgc cgtcgcccgg cccgtggtcg tgtggcccgt ggttgtctgg
    11341 cccgtggtta acgggacagg tcaccagcag gctcgggtcc gattgcggcc tgcccgcctc
    11401 cagagccgcg aacgtcgact cccactcccg cccgaagtgc agggtgtgat gggcctggcc
    11461 ctccgggcgc cggtcgagcg cgaagtgcgc caccaggcag gagggggaga agcggggccg
    11521 ccgcagccgc cagtcggccg cctcctccgg cagcaggccg tcgccgcccc gccggccctg
    11581 cgcccggacc aggtcgcagg ccaccacggc gtgccgggcg gcgagccgtt cgccggtggc
    11641 gaggcggacg gcgaccaccc ccgcgccgtc ggtctcgatc cgcgtggccc gcacgccgta
    11701 ccggaagacc gccccggcct tctccgcggc ggcggccatg gcccggggga cggcgtgcat
    11761 gccgccctcc ctggggaagt agaccccgcc gaccgtgtcc atgtgcgcga tcaccgcgta
    11821 cacgccgagg gcgcggcgcg gcgacaggcc gacgtacagt gcctggaagg tgtgcgccct
    11881 gatcagccgc tcgtcggtga ggtgacgccg cacgagcccg tccagccggc ggaagccgcc
    11941 gagcgcggcc agccgcgcca gcgcgtacgg ccgggccagc gcccgcagcc gggtcatgtc
    12001 ccggtcgatg aaggcacccc actcggcttc gaacatctct ccgagcaggc gccggaaccg
    12061 ctggtagcgc cgggcctctt cgggcccgga cagctcccgc acctgctcgg ccatcgcgtc
    12121 ggcccccgcc accacgtcga gccgcgaacc gtcgtggaag gtcagccggt agtacgggtc
    12181 gagccgccgc agcggcagcc agcgctccat gtcctgcccg gcggcggcga aggtgtcggc
    12241 cagcaccccc ggcatggtca gcaccgaggg gccggtgtcg aagcggtggg agcccagggt
    12301 cgccgtgccg cagcagccgc ccggcacgtc ggaggcctcc acgaccgtca cctcacggcc
    12361 cgccccggcc aggcgcatcg cggcggacag accgcccagc ccggcgccga tcaccacgac
    12421 cggcccgccc gcggtcatca ggccgccccg ccggcggcgg gctcggcgga gccggccgga
    12481 ggggcggggc cgggggaggc cgcgtttccg gcctggccgg gccgagccgc gtggtcgggc
    12541 cgagccgcgg ggtgggggtc ggccgcgggg tgggggtcgg ccgctgagtg gggctgggcc
    12601 aggcggaggg cgaggccgag cagggccgtc cgggcgtccg ccggcatgtc cgccccggac
    12661 agcgcctcgc ccgcggactc ggtcaggtcg cggatgcgcc gctcgaccgc ctccagcgcg
    12721 ccggtcgcga cgatcacctc ccgggccgcg gccaggcggt ccggctgcgc ctcgcccgtg
    12781 cccggcagtg cgtccagcag cgccgctccc gggccgtccg cgcgttcgcg cgccaacgtc
    12841 agcaggtagg tccgcttgcc ctgcagcagg tcggccccgg cgggcttccc ggtccgggcc
    12901 gggtcgccga agacgccgag gacgtcgtcg cggagctgga acgcctcgcc cagcgggagg
    12961 gcgtacgcgc tgaggacccg gcgcagcccg gggtcgccac cggcgatggc gtgaccgagg
    13021 tgcagcggcc gttccaccgt gtacctgccc gacttgtacg tcgagatcag cagtgcctcc
    13081 cggtggtcgc cgccgccccg ggcggcgcag gtcaggtcga ggtactgccc ggcgatcagc
    13141 tccacgcgga gctgggtgaa gacctccagg gcgtcggcca gcctgcggcg gtcggccagc
    13201 agcgcggagt cggcccaggt gaaggcgagc acgccgagca ggatggcggc cgactccccg
    13261 aaccgctgcg acgacccggc ccagccgagc tcccggtgac gctcggcgag cgccaggtgg
    13321 gcggtcgtcc ggccgcgcct gaggggcgac tcgtccatca cgtcgtcgag gatcagcgcg
    13381 cacgcgtgga ggagctcgat cgagcagccc gccgccagca cggccccgag gtcgtcgggt
    13441 gagccgccgc aggcccggtg cccccagtac acgaacgccg gccgcagccg cctgccgccg
    13501 cgagcgacga agtcggcgag gtgacgtcgc agcacctccc ggtcgtcggc gccaaggaag
    13561 gacaatcggc tcagctcgcg ccggagcagc tcgtccaggg cgtggtcgaa cagaccggaa
    13621 aggtggcgat cgaacggctc ccgcgggtcg tcccgaacgc cgccggtctc gcgggtcaac
    13681 gtcagcatgc gcactgctcc ttcgatcgtt acggtgatcg gcggcgccgt cagtagagtt
    13741 ttcgcgcccg cccgctccgg cggttgcatc cgggcaaggc ccccgggccg aaacacggtc
    13801 aggggcggca cgggcgccgg gcgcgatggg cgcggcgacg accggatgga cacggggtga
    13861 gcacgtgacg cgcgagggcg ggtcgggggc cggtgagcac gcggccgccg aagaggagcc
    13921 gggctacggc atcggggccg tctcccgtcg gctcggcgtg cccgcgtcca cgctgcgcac
    13981 gtggaatctc aggtatggca tcggccccag caggcgcagc cccggcgggc accggcgcta
    14041 cgacgacgcg gacctgcgcc gcctggagga gatgaaccgg ctgatccgcg ccgggatgcc
    14101 gccggccgac gccgccaggc aggcgctgcg gcttaggccc gcgccggggg agcgggcggc
    14161 gtccgccccg gcccgggagg gggccgcgtc accggagtcg cccggacggc cggagcccac
    14221 cgtgccgtcc gcctccgccg tacggccggc cgccgacccc ggattgctgt cggcggcgat
    14281 gctggcccgc gcggtgacgg tgctggacac cgcgacggtg gacgcgggac tggacgcggc
    14341 gctggccgcg cacggcgtga tgtggacgtg ggagcggctc gtgctgccgg tgttcgcggc
    14401 cgtcacccgc aggcagcagg acaccggagc cgggatcgac gtcgagcacc tgttctccga
    14461 ccggctccag gccgcactgg cgcggttctc cgcgcgcgtg ccctcgcccg tgcatccccg
    14521 tcctgtcctg ctggccgccg cggaggagga gcagcacgcg ctgccgatcc acgcgctggc
    14581 cgccgcgctc ggcgtgctcg gggtggagac ccgcgtgctc ggggcgcgca cgccgtacac
    14641 cacgctggcg gacgcgatgc ggcgcctcgg tcccgcggcg gtgttcgtgt ggtcgcagct
    14701 gcgggagacg ggcgatccga ccccgctggc cggtctgccg gggctccgtc ccgcctgccg
    14761 tgtcgtggtc ggcggccccg ggtggcgcga cggcctgccc acgcatgtca tccgggtgaa
    14821 cacgtttcgt gacgccctgt cggcggtaat gaccactctg cggtgattcg ccctctttgg
    14881 cgcatctttg atccggtgtt cggcccccat ggttgtccgc tgccagcgcg ggcagctatg
    14941 aataggtttt gaataagttt tcgccgagtc ttctgcccaa ggggggccga tggaggagac
    15001 cctggagttc cgcctcgccg cgggggacac gggagcgctg ggggagtgct accgggtgca
    15061 ctcgccggcc gtgcgctcct acctgcgcaa actcgtgccg ccccaggatg tggaggacgt
    15121 catgcaggtc gtcttcaccg aggtgtggcg cttccggcac cgcttcgacc cgggccgcag
    15181 cctgccggcc tggttgttcg gcatcgcccg caaccgggcg gtggaccacc tgcgggcgcg
    15241 ggccccggcg acggtgccgc tggaggcggt ccccgacccg gcggggcgtg acggccggct
    15301 ggacggcgac cagttcgccg accgcgaccg aatccgccga gcgctggcct cgctgccgca
    15361 ggtgcagcgc caggcgatcg agctggccta ctacggagac ctgacgcagc gggagatcgc
    15421 cgagcgcctg cgggtcccgc tcggcacggt caaggcgcgc acggcccgcg gcctgcaccg
    15481 cctgtccacc ctgctgcggc cggcggcctg accacggggc ctaaggagta accccgttcc
    15541 cgcatgagtg cggacgaggg ggaagaaaga ggacgcatga gacgcacatc gaagaagacg
    15601 ctggtgcgga cggccctcgc ggtgaccgcg acggccgcgg tcggcggcct gtccaccgac
    15661 gcccgctccg gctggtgcgc ccgcctgcgc aagccctcct ggcagccgcc gccgaaggcg
    15721 ttcggcctgg tctggacgcc gttgtacgcg acgatcgcct acgcctccgc ccgggcgctg
    15781 tcgcacgggg acgacggctc ccggccggcc ctgcggcgtg cgctcgccgc caacctggcg
    15841 ctcaacgcgg cctggccgcc gctgttcttc aaggcccgca acccccgcct cgcgctcgcg
    15901 gagatcctcg cgctcaacgt gtcgaacgcg ctgctgaccc gccgcctcct ccggcaggac
    15961 cgcacggccg ggcttctgct gctgccgtac gccgggtgga cggtcttcgc caccgcgctc
    16021 aacgccgcca tcgcccggca caacccggaa gcgcagcaca acccgaaggt ctgagggtca
    16081 gccgatcgca tccatctccg gcctgctgac tggtgcttcg aagccacgca ggctgactcc
    16141 tgtcggttgc tgcgacgtcg agggtcagac gcggagcagg tcggtcgaga ccgtccagag
    16201 gcgcttggcg gcagtggggt cgagcgccca ttccttgacg ccgtgcgggt gctgcgcgag
    16261 gtcggcgtcg tccggcacgg tgtaagcctc ttgtgagtcg tcgaggtagt ggcctccgaa
    16321 gtgggcgaac tctggggcga cggccgcgac gatgctggtg gcggctccct gctcgaccgt
    16381 cttgtaagtg aagattccgg cggcctcggc cgcgtcgagc gatgccttct gctgcgcggt
    16441 gaagttgcgc tgcagtcccg tcgcgacacc gccggggttc accgcattgg cgatgatgcc
    16501 gtcggaggcc cagaggcgag tcgcctcgac ggcgaagaga gagttcgccg tcttcgactg
    16561 ggcgtaggcg atctgcgggt cgtagctgcg acgctcgaag tggaggtcgt cgaagtcgat
    16621 gccggaacgc atgtgcgcgg tcgaactgac cgagacgatc cgtgctccgt caccgtcggc
    16681 cgctcccagg gtcagggcgt cgtgcaggcc ggtggcgagg gcgaagtggc cgagatggtt
    16741 cgtcgcgaac tgcagctccc agccctcacg cgtacgttcg aggccaccgg tgaccacgcc
    16801 cgcgttgttg atcagcagat ggagtggacc gttccacgcg tcgacgaatc gcgcgacggt
    16861 gcttctgtcg gcgaggtcga gccggacgac tcggggccgg atctgtccgg tcgacttcgc
    16921 gatcgtctcg gcgacggcgt cgcccgcggt cgtgttccgg acggcgagcg ttacctccgc
    16981 tccggcggag gtcagcgcac gagcggtctc ggtgccgatt ccggaggaac ctccggtcac
    17041 gatcgcgcgg accccggtga ggtcgacgcc tcgcagcacc tcgtccgcgg tgctggagga
    17101 ggtgaagggt gtagtgatga gttcgcgcat ggtcatggcg gtgactatac acactagatg
    17161 ggttttgtat agtgcgccgc tcgctcgtat gctcgtttca tgagcagtcc cgaggtcggt
    17221 cacccaccgt cgacagtcgc cgataccgat cgtcggatca cggttctgga ctccgcgatg
    17281 gtcacgttcg cgcgattcgg ttaccggaag acctcgatgg aggaggtcgc gcgggcggcg
    17341 ggcatctcgc ggcccgggct ctatttcctc ttctcctcga aggagactct gttccgtgcg
    17401 gcggtcaccc aggccctgaa tcgcgatatc acagcggtcg aacacgtcct ggccgacacc
    17461 ggccgacccc tttcggagcg tctcgtcgaa gcgttcgatc agtgggcagg ccgctacatc
    17521 ggcccgctgg cgagcgatgt cgcgatggtc atcgaggaca atcccgacct cctcggagag
    17581 atcatcaaga ctccgcggcg acgtttcgag gaactgatca cagacgcggt cgccatcacg
    17641 tcgggacgcg aggcggctcc ccttgtcgcg cagacgatga tcagcgcgtc gatcggaatc
    17701 aagcatcagg tcgcgtcacg ggaggtctac ctcgaacggc tggaggtagc catcgatctc
    17761 ctgctgcgct gatcaggcgt gaccatgtcg cgcgcgagac cggccgcggc cggatctcac
    17821 tgcgccggat cttggtgcgg ccggatctcg ctgcggccgg atctcggtgc ggtcggatct
    17881 cactgggcgg cggcgtcgag cgcgggcgaa ccctcggcct ccgcggccct gtggtactcg
    17941 aaggccgaca ggatcgtgtc gaggatctcg ccgaactgcc gcacctgacc aggggtgagg
    18001 gggtcgaaca gcacccggcg gacctcctcg acatggcccg gcgccgcctc cacgagcgcg
    18061 gcgaagccct cgtcggtgag ctcggcgacg gtcgttcgcc ggtcctccgg ccgcttgagc
    18121 cgccgcaccc agctcttctc ctccagccgg gagacggcgt gggacaggcg gctcaccgaa
    18181 tactggagga tggccgacag ctcggtcatc gtcatggtcc gcccgggcga ctcggagagg
    18241 accaccagga tcatgtagta ggcgtgcggc atgcccgagt cgcgctgcag ctgccgttcg
    18301 agggcctcct gcaggagctg gctggtccgc aggtaggaac gccaggtgtg ctgctcctcc
    18361 tcgtcgagcc atcgggtgcc ggacatggcg ccaagactac cgtcggtggg cacgctgttt
    18421 tgtgggcgaa agaccctggt tcacccgcca ccgctgggaa agtgtcaggg gcatggacgc
    18481 atacgggaac atcgacgcct actggcgggc cgcgaactat ctgtccgtcg gccagatcta
    18541 cctgatggac aacccgctgc tgaccgagcc gctcagcccc gagcacgtca agccgcggct
    18601 gctcggccac tggggcacga cgccggggct caacttctgc ttcgcgcacc tcaaccggat
    18661 catccgggag cgcggccagg acatgatcta catcgccggc cccggtcacg gcggcccggc
    18721 ggcggtcgcc cacgcgtggc tcgaaggcac ctacaccgag cgctaccccc atgtgaccca
    18781 ggacgccgag ggcatgcgca ggctcttccg ccagttctcc ttccccggtg gcatccccag
    18841 ccacgtcgcc cccgagacgc cgggctccat ccacgagggc ggcgagctcg gctacgccct
    18901 ctcccacgcg tacggcgcgg ccttcgacaa ccccagcctg gtggtggcct gcgtcgtcgg
    18961 cgacggcgag gccgagaccg gcccgctcgc caccggctgg cattccaaca agttcctcaa
    19021 ccgggacacc gacggggtgg tcctgccgat cctgcacctg aacggctaca agatcgccaa
    19081 tccggccgtg ctggccagga tcccggagga cgagctggtc aagctcttcg aggggtacgg
    19141 ctaccgcccg cacatcgtcg ccggccagga accggcggag atgcacgagc tcatggccga
    19201 gaccctcgac accgtcttcg agcagatggc cgaccgcggc ccgctgccga tgatcatcct
    19261 gcgtacgccg aagggctgga ccgggccgcg cgaggtcgac gggctcccgg tcgagggcac
    19321 gtggcgcgcc caccaggtgc cgctgaccga cgtgcggaac cggcccgacc ggctggaggc
    19381 cctggaggag tggatgcgct cctaccggcc cgaagagctc ttcgacgtcg acggacgtcc
    19441 ggtcgagatc atcacgcgga ccgtcccgga cgggccgctg cggatgagcg ccagcccgca
    19501 cgccaacggc ggggagctgc tgcgcccgct cgtgctgccc gacttccgcg actacgcggt
    19561 cgaggtcaag gcgccggcga gcgcctccag cgagccgacc cgcgtcctcg gggcgttcct
    19621 gcgcgatgtc atcgcggcca accctgcgaa cttccggctg ctcggcccgg acgagaccgc
    19681 ctccaaccgc ctgtcggccg tattcgaggc gaccgacaag gagtgggagg ccgccctgct
    19741 gccgaccgac gagaacctcg gcccccgggg cagggtcatg gaggtgctca gcgagcacca
    19801 gtgccagggc tggctggagg gctacctgct gaccggccgc cacgggctgt tcaactgcta
    19861 cgaggcgttc atccacatcg tggacgcgat gttcaaccag cacgccaagt ggctggagtc
    19921 ctcccgcaag atcccgtggc ggcggccggt cgcctcgctg aactacctgc tgtcctccca
    19981 cgtctggcgt caggaccaca acggcttcag ccaccaggac cccggcttcc tcgacgtcgt
    20041 cctcaacaag aaggccgagg tcgtccgggt ctacctgccg ccggacgcca acaccctgct
    20101 gtcggtcgcc gaccactgcc tgcgctcgcg cgactacgtc aacgtcgtcg tggcgggcaa
    20161 gcagcccgtg ctcgacttga tgagcatgga cgaggcggtc gtccactgca cccgcgggct
    20221 gggcatcctc gagtgggcct ccaccgacgc gggcgccgag cccgacgtcg tgctcggctg
    20281 cgccggtgac gtgcccacgc tggagaccct ggccgccgcc gcgctgctgc gcgagcacct
    20341 gcccgaactg cggatccggg tgatcaacgt ggtcgacctc atgcggctgc agccggcctc
    20401 cgagcacccg cacggcatga gcgacgccga gttcgacgcg ctgttcacca cggacaagcc
    20461 gatcatcttc aacttccacg gctacccgtg gctgatccac cgcctgacct accgccgcac
    20521 tgggcacgac aacctgcacg tgcgcggcta caaggaggag ggcaccacga ccacgccgtt
    20581 cgacatggcg atgctcaacg acatcgaccg cttccacctg gtgatggacg tgatcgaccg
    20641 ggtgcccggc ctgggcggca ggacggccca cctgcgccag cgcatggccg acgcccggct
    20701 gcgcgcccgc gcgtacaccc gcgagttcgg cgaggacccc gccgagatcc gcgactggac
    20761 gtggccctac tgattccggg aggcgagtcg gcagcgggga cggcggcgag tccgacggcg
    20821 ggcatggcgg cgggcatggc ggcggacgcg gcgcatcacc gccattcggg ggcgacggca
    20881 ccggtagcat cggatgcgac cggagccgcc gcctcgggcg cgcggccatc cgagatccat
    20941 gcgccgacct gtcctaagga gccaccgtgt ccgccgccct tgagatacgc atcaccctcg
    21001 ccggagccga gcgcgtggtg gcggcgggta cgacggccgg ggaggcgctc ggcgccgacg
    21061 gcaggtcggt gatcgccgcc cggatcgacg gcgagctgcg cgacctggcc accgaggtcg
    21121 ccgagggcga cgtggtcgag ccggtcgcga tcgacagccc cgacggccgg gccatcctgc
    21181 gccactccac cgcgcacgtc atggcccagg ccgtccagga gatcttcccc gacgccaagc
    21241 tcggcatcgg cccgccggtc gagaacggct tctactacga cttcgacgtc cgcgagccgt
    21301 tcacccccga cgacctcaag cgcatcgaga agcgcatgcg cgagatcgtc aagcaggggc
    21361 agaccttccg gcgccgcccg atcggcgacg acgaggcccg cgccgagctc gccgccgagc
    21421 cgtacaagct ggagctcatc gggctcaagg gcggcgcggc cgacgcggcc gacggcgcga
    21481 acgtcgaggt cggcggcggc cagctcacca tctacgacaa cctcgacgcc aagtcgggcg
    21541 agctgtgctg gaaggacctg tgccgggggc cgcacctgcc gagcacccgg gtcatcccgg
    21601 ccttcaagct catgcggtcc ggcggcgcct actggcgggg cagcgagaag aacccgcagc
    21661 tccagcgcat ctacggcacc gcctgggaga cccgcgagaa gcaggacgag tacctcaagc
    21721 tcctggagga ggccgagaag cgcgaccacc gcaagctcgg cgccgagctc gacctgttct
    21781 ccttcccgga cgagctgggc tccggcctgc cggtgttcca ccccaagggc ggcgtgatcc
    21841 gccgggtgat ggaggactac tcgcgccgca ggcacgagga ggcgggttac tccttcgtca
    21901 acaccccgca catcacgaag gacaacctct acaagatctc cggccacctc gactggtacg
    21961 ccgacggcat gttccctccc atggagctgg agggcgcgcg ctactacctc aagccgatga
    22021 actgcccgat gcacaacctg atcttcgggg cgcgcgggcg gtcctaccgt gagctgccgc
    22081 tgcggctgtt cgagttcggc acggtctacc gctacgagaa gtcgggcgtc gtgcacggcc
    22141 tcacccgcgt acgcggcctg acccaggacg acgcgcacat ctactgcacc cgcgagcaga
    22201 tgcgcgacga gctcacctcg ctgctgcggt tcgtgctcga cctgctgcgc gactacggcc
    22261 tggaggactt ctacctggag ctgtccacca aggacccgga gaagttcgtc ggctccgacg
    22321 agacctggga ggaggccacc cagaccctgc gggaggtggc cgagtccgag aagctggagc
    22381 tggtcctcga cccgggcggc gcggccttct acgggcccaa gatctcggtg caggcccggg
    22441 acgccatcgg ccggtcctgg cagatgtcga ccatccagct cgacttcaac ctgcccgagc
    22501 gcttcggcct cgaataccag gcttccgacg gcacccggca gcagcccgtc atgattcacc
    22561 gcgcgctgtt cggctcgatc gagcgcttct tcggcgtgct ggtcgagcac tacgcgggtg
    22621 cgttccccgc gtggctcgcc ccggtgcagg tcgtcggcat cccgatcgcc gacgcccacg
    22681 cgccctacct gcaggacgtc gccaagcggc tgcgcgagca gggcatcagg atcgaggtcg
    22741 acgagagcga cgaccgcatg cagaagaaga tccgcaacgc ccagaaggcc aaggtgccgt
    22801 acatgctgct cgcgggcgac gacgacatcg cggccggcgc ggtgtccttc cgctaccgca
    22861 acggcgagca gaagaacggt gtgccgatcg accaggcgat cgacgagatc gtcgacgcgg
    22921 tccgccgccg cgtccaggtc tgacccgtca tcgccgcgaa cgcgggcggc ccccatccgg
    22981 ggcccccgcg ttctcgctcc tcccggcagc gtggggaatc ccgcggctgt gggaaggtcc
    23041 tccggcggca ccggccggac accggtcggc accaaaccgg caccgggccg atatcggctg
    23101 acaccggccg gcaccgcgct gacaccggcc agcactgggc cagcaccgcg cctacaccgg
    23161 gcgggctcag gcggccgggg cgtcctcgcc gggggcgtcc tgaccgggga ggcggacgtc
    23221 gtcgacggtc acgttgacct cgaccacgcg catgccgagc atccggctca ccgacctggc
    23281 cacgttgacc ttgacctcgg tggcgacgtc catcaccacg tggccgtaca cgatgacgat
    23341 ggtcacgtcg accgagacct gccggtcctg gatgctggcc tgcacgccct gcgtcgcccg
    23401 cttggtcccc acgccgatgc ggtcgcgcac ggattcgaag gcacgctcca ggtcgccacc
    23461 caggtcggcc acgccgggga tctcaagggc ggccagcgcg gccaccttct ccaccacctc
    23521 gtcggcgacc ttgatccggc ccttgaggac gtcggcggcc ggcgtcccgg gcctcggcgt
    23581 ctccggggag aggtccggct cggccggaac ggccgcctcc acgcccgccg ggtcgtcgag
    23641 gctcccctcg gcgtacgcgt cggtctggtc ttccactcgc tcctcgac
//
