LOCUS       NZ_BMMN01000004        21068 bp    DNA     linear   CON 22-DEC-2024
DEFINITION  Microbispora bryophytorum strain CGMCC 4.7138 sequence04, whole
            genome shotgun sequence.
ACCESSION   NZ_BMMN01000004
VERSION     NZ_BMMN01000004.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Microbispora bryophytorum
  ORGANISM  Microbispora bryophytorum
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Streptosporangiaceae; Microbispora.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 609914)
  AUTHORS   Sun,Q. and Zhou,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 202X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014645855.1-RS_2024_12_22
            Annotation Date                   :: 12/22/2024 07:39:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,203
            CDSs (total)                      :: 7,136
            Genes (coding)                    :: 7,048
            CDSs (with protein)               :: 7,048
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 16 of 88
            Pseudo Genes (incomplete)         :: 78 of 88
            Pseudo Genes (internal stop)      :: 7 of 88
            Pseudo Genes (multiple problems)  :: 11 of 88
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:18:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 356970
            Orig. end                         :: 378038
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMMN01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21068
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="3"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21068
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21068
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11068](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11068)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(430..439)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            1213..2190
                     /gene="alc"
                     /locus_tag="IEY80_RS14545"
                     /old_locus_tag="GCM10011574_29470"
     CDS             1213..2190
                     /EC_number="3.5.3.4"
                     /GO_function="GO:0004037 - allantoicase activity [Evidence
                     IEA]"
                     /GO_process="GO:0000256 - allantoin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="alc"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541667.1"
                     /locus_tag="IEY80_RS14545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_29470"
                     /product="allantoicase"
                     /protein_id="WP_142568484.1"
                     /transl_table=11
                     /translation="MTGFTRLPDLALRTYGGSVVAANDESFAEREALIRPGPAEFRPHT
                     FGAKGQVYDGWETRRRREPGHDWAIVRLGLPGIIRGVVVDTAWFRGNYPPYASVEACAA
                     EGHPAPDELDGWVEIVPKSPLKGDTVHEFAVTDPRRFTHVRLNIFPDGGVARLRVHGRV
                     VPDRTFLEGLTVDLAALENGGLVTACSDEFYSSPNNVLAPGLARNQAEGWETARRRDGG
                     NDWLVVALAGPGRVAVAELDTTNLVFNAPGWVSLKGVDADRAPLEDEDAWFPLLPMTRL
                     QPDTRHRFRLDDDRRITHARLDIHPDGGLARLRLLGTLAPWSPP"
     gene            complement(2429..4450)
                     /gene="pknB"
                     /locus_tag="IEY80_RS14550"
                     /old_locus_tag="GCM10011574_29480"
     CDS             complement(2429..4450)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131588.1"
                     /locus_tag="IEY80_RS14550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_29480"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_142568485.1"
                     /sec_met_domain="Pkinase (E-value: 3.7e-54, bitscore:
                     179.0, seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 1.1e-07, bitscore: 27.1,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTTLTDPLVGQVLDGRYRVESRIARGGMASVYLALDVRLDRTVA
                     VKVMHRSLAEDPQFVRRFIGEAKSVASLSHPNIVQVFDQGTDGANVYLSMEYVPGRTLR
                     DVLRKRGHVPAREALEMVIPVLAALGAAHQAGLIHRDVKPENVLLADDGRVKVVDFGLA
                     RAIEATNQTKTGMMIGTIGYMSPEQVTTGTADARSDVYAAGIMLFELLTGRQPYAGETP
                     MSVAYRHVHETVPAPSLSVADVPPSIDALVAAATDKDPAARPADATAMLVAAVEIHRTL
                     PRTGHTGAHSALHGAPHGTPHGTYDSGAHSGVRTGAHRTLPPPGGSSPFGTAQHARPEH
                     EPPADRTMIQPRSELLTGRAEAGRRRRRGIRPVWFVAALALVMLAGVAFTGWWFSQGRY
                     TKVPDLVNKPVTVARQAAQQAGFEVRIGEARFDDKVPKDIVLDTDPGLGAEVVKGSVLT
                     LIPSAGPETVPVPKVENVSLADARAKIADAGLTPGRVSKSASDTVPRDQVIRTNPPVGK
                     RVKKGSTVNFVVSAGLLMPDVTQMMRDQAEKFLREKGFNVQIDETTDDTPPGTVIAQDP
                     PGGAEVVAGGTVHLTASRGPDQGFHWPWEVNPADPGQSPPAVVNVPNVMFKSVKDAVNE
                     LKAAGFNVKTRKMVGTDRVVGENPLGQQPPGATITIWH"
     gene            complement(4641..5405)
                     /locus_tag="IEY80_RS14555"
                     /old_locus_tag="GCM10011574_29490"
     CDS             complement(4641..5405)
                     /EC_number="2.8.1.10"
                     /GO_function="GO:1990107 - thiazole synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018658554.1"
                     /locus_tag="IEY80_RS14555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_29490"
                     /product="thiazole synthase"
                     /protein_id="WP_142568486.1"
                     /transl_table=11
                     /translation="MTDDVFVLGGEKFTSRLVMGTGGAPSLEVLDQALEASGTELTTVA
                     MRRLDPESRGSVLDVLRSRGIKVLPNTAGCFTAGEAVLTARLAREALETDWVKLEVIAD
                     ERTLLPDPIETFDAAERLVADGFTVLPYIGDDPALARRLQDAGCAAVMPLGAPIGSGLG
                     IRNPHSIELIVEAATVPVILDAGIGTASDAALAMELGCDAVLLASAVTRAHRPGLMAAA
                     MRQAVTAGRLARLAGRIPRRRYAEASSPARTS"
     gene            complement(5408..5608)
                     /gene="thiS"
                     /locus_tag="IEY80_RS14560"
                     /old_locus_tag="GCM10011574_29500"
     CDS             complement(5408..5608)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131590.1"
                     /locus_tag="IEY80_RS14560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_29500"
                     /product="sulfur carrier protein ThiS"
                     /protein_id="WP_142568487.1"
                     /transl_table=11
                     /translation="MKVTINGGAAELPDGATIGDAVRTLTSLTSGVAAALNGEVVSRSA
                     WDTTPVADGDGVEVLTAVQGG"
     gene            complement(5605..6741)
                     /gene="thiO"
                     /locus_tag="IEY80_RS14565"
                     /old_locus_tag="GCM10011574_29510"
     CDS             complement(5605..6741)
                     /EC_number="1.4.3.19"
                     /GO_function="GO:0016647 - oxidoreductase activity, acting
                     on the CH-NH group of donors, oxygen as acceptor [Evidence
                     IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene="thiO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017614369.1"
                     /locus_tag="IEY80_RS14565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_29510"
                     /product="glycine oxidase ThiO"
                     /protein_id="WP_142568488.1"
                     /sec_met_domain="DAO (E-value: 2.3e-71, bitscore: 236.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRTPPSGVRSGYDVVIVGGGVEGLAAAWRTARRGLSAAVVDPAP
                     GGGATHASAGMLAPVSEVTYTEEPLLRLGLASLAAWPAFRAELEDETGDDLDYRTEGTL
                     EVARGADDMAVLDDLAAFERTLGLRVERLTGRECRSYEPMLSPSVRGGLLARDDAWVNP
                     RRVVRALLTAFEKAGGTLVTERVAGIDAPGPGAPCVRLESGGVIAAGQVVVAAGSWSAS
                     LLPSLPVRPVKGEILRLRGPRGFLTRCVRGLVHGSPAYLVPRGDGEITVGATTQEMGFD
                     PRVTAGGVYELLRDARELVPGITELELAETTTGFRPGTPDNLPIIGPAGPPGVLAATGH
                     GRNGVLLSPITADAVAAFLTGDEVPPVARFCDPGRFSQ"
     regulatory      complement(6730..6840)
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /regulatory_class="riboswitch"
     gene            6951..7490
                     /locus_tag="IEY80_RS14570"
                     /old_locus_tag="GCM10011574_29520"
     CDS             6951..7490
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020380129.1"
                     /locus_tag="IEY80_RS14570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_29520"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_142568489.1"
                     /transl_table=11
                     /translation="MATLLYSATMSLDGFIAGPDGDMSWLTEHLGPNPDVDGLVGDIGA
                     LLVGNRTFRGDDPNRGTSQEGAFGGVWSGPQFVLTHDLPAAPVPGVTFVTDLGAAVEAA
                     TAAAGDKYVNMLGADVAAQCLDAGLLDEILVCVAPVMLGDGVRLFSRPGGDRVRLERIS
                     LTHVPHATNIWMRVVR"
     misc_feature    7600..7620
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            7613..8791
                     /locus_tag="IEY80_RS14575"
                     /old_locus_tag="GCM10011574_29530"
     CDS             7613..8791
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889487.1"
                     /locus_tag="IEY80_RS14575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_29530"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_142568491.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.3e-52, bitscore:
                     174.0, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDHVVVVGAGLAGVRSIEALRAGGFTGRITLIGEEHHRPYDRPPL
                     SKAVLLGETDSTVVDSDLDALDVRLCLGTAAKGLRDGVLETTEGELEYDGLVIATGATP
                     IRLRGEGRQHVLRTIEDALTLRERLVPGARVAVVGAGWIGAEVATAAARAGCAVTVVEA
                     GESPLAVALGPAVGSHTTDWYARAGVELRLGAMVGTVDADGLTLMSGARVPADVVVTGI
                     GVRPAVDWLKGSAVRLDDGVVVDEHLRTSLPNVVAVGDCANWWSRRFHARLRVEHWDTA
                     LQAPDTAAATLLGEEAVYDPVPYFWSEQFGHMVQFAGHRDAGDRMVLRGDPRRDPKWSV
                     CWLTADDRLAAVLTVDRPRDVVQGRKIVESGRRLDPLRVADAAVALRDCIMA"
     gene            8835..9209
                     /locus_tag="IEY80_RS14580"
                     /old_locus_tag="GCM10011574_29540"
     CDS             8835..9209
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131593.1"
                     /locus_tag="IEY80_RS14580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_29540"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_142568492.1"
                     /transl_table=11
                     /translation="MTLTVAKIDRETDQLVGEWLPLSEAAEKLVLSIGRAKQLLKDKKL
                     VGVRRGGGEPQIPAVFIADGEVLKGLPGTLTVLADAGYDEVESIRWLFTPDDSLPGSPI
                     DAIVGGRHTEVKRRAQALGF"
     gene            9247..9891
                     /gene="thiE"
                     /locus_tag="IEY80_RS14585"
                     /old_locus_tag="GCM10011574_29550"
     CDS             9247..9891
                     /EC_number="2.5.1.3"
                     /GO_function="GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1280: thiamine-phosphate pyrophosphorylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131594.1"
                     /locus_tag="IEY80_RS14585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_29550"
                     /product="thiamine phosphate synthase"
                     /protein_id="WP_142568939.1"
                     /transl_table=11
                     /translation="MRRQRLAQARLYLCTDGRRGRGDLEKFLDAVLSAGVDIVQLREKG
                     LEAREELDLLEVFRAACDRHGALLAVNDRADVAYAARPDILHLGQDDLPVPVAREILGP
                     DVLIGRSTHSAAEASAAAVQPGVDYFCCGPIWPTPTKPGRPAPGPALLEHAARLGADRP
                     WFGIGGIGPDNLDEVMAHGVRRAVVVRAVTEADDPGAAAAALKARLSAVPL"
     gene            complement(10001..11068)
                     /locus_tag="IEY80_RS14590"
                     /old_locus_tag="GCM10011574_29560"
     CDS             complement(10001..11068)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131595.1"
                     /locus_tag="IEY80_RS14590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_29560"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_142568494.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.2e-51, bitscore:
                     170.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTASAASLDSIRTEVDRALRDFLDRQRPHFSDPHLAALLSAAEDF
                     IAGGKRLRPAFCHWGWRAAGGGDDPGLHVAAASLELLQASALIHDDVMDASDVRRGMPS
                     AHRRFERMHAEAGWHGSGRQFGEGTAVLLGNLLLVWSGEMWRTSGLAPEAIAAAQPLHD
                     YMLTELMCGQYLDLLEQAQGESTFDSALRVALYKSGKYSVEQPLRLGLVLAAQASHAWI
                     DRLCVQYGQQVGIAFQLRDDILGVFGDPAETGKPAGDDLREGKRTVLIARALASATPAQ
                     TAVVRSLLGDPALDAEGVAQLRTVIEETGALAACEGMIKRYLDDALHALDQAPIEEEAR
                     TALAALAVAATSRRT"
     gene            11209..12138
                     /gene="metF"
                     /locus_tag="IEY80_RS14595"
                     /old_locus_tag="GCM10011574_29570"
     CDS             11209..12138
                     /EC_number="1.5.1.20"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131596.1"
                     /locus_tag="IEY80_RS14595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_29570"
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="WP_142568496.1"
                     /transl_table=11
                     /translation="MALGLPSRLPDRVPTVRELLAAGERSFSFEFLPPKTDEGERQLWR
                     AIRELEALRPTFVSVTYGAGGSTRDRTVDIVERLAHETTLTPVAHFTAVDHSIRELRHL
                     VGRFADAGVRNILAVRGDPRGGNPLDEWVKHPEGVLYAEELVRLIRQAGDFCVGVAAFP
                     YKHPRSATIESDTEYFVQKCRAGADYAITQMFFEADDYLRLRDRVAARGCDTPIIPGIM
                     PVTQMSTIARSEQLSGAPFPPELAERFAAVADDPAAVRRLGIEHAIEMCRKLLDEGAPG
                     IHFITFNRSSATREVFQALHGVPAAVAG"
     gene            complement(12154..12729)
                     /locus_tag="IEY80_RS14600"
                     /old_locus_tag="GCM10011574_29580"
     CDS             complement(12154..12729)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889492.1"
                     /locus_tag="IEY80_RS14600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_29580"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_142568497.1"
                     /transl_table=11
                     /translation="MIQLRRVGPDEFRAALDTVLEIYAVAMRPPSDQLAGRMAIMRNHA
                     TYPDFDCVLAEDTQASGVAGFAYGFHGGQGQWWHEVVRGALQDRAGPVVANAWFGDALE
                     IAEIHVRPEYQGRGIGRRLIHTLCEGRPERTAVLSTHDAPTVARHLYRDVGFADLMTRF
                     VFPGGYEEYVIAGVRLPLPLPEGAALEG"
     gene            complement(12773..13249)
                     /locus_tag="IEY80_RS14605"
                     /old_locus_tag="GCM10011574_29590"
     CDS             complement(12773..13249)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131598.1"
                     /locus_tag="IEY80_RS14605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_29590"
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_142568498.1"
                     /transl_table=11
                     /translation="MAEKLHPNVVRVQEALRAHAVTGEVVVLDEAAPTAATAAAQLGCE
                     VGAIANSLIFDADGAPLLVLTSGAHRVNTDLIARLVGAAKVRRATPEFVREHTGQPIGG
                     VAPVGHPAPVRTLVDTWLSKHDVVWAAAGHPHTVFPTSYDELLRTTGGTAAEVE"
     misc_feature    13232..13248
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.72"
                     /tool="antismash"
     gene            13376..14254
                     /locus_tag="IEY80_RS14610"
                     /old_locus_tag="GCM10011574_29600"
     CDS             13376..14254
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853346.1"
                     /locus_tag="IEY80_RS14610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_29600"
                     /product="L,D-transpeptidase family protein"
                     /protein_id="WP_223852712.1"
                     /transl_table=11
                     /translation="MMRGRRRLLVVAGAATFATAFAVAGVSGPAQARAAAPTGTVATGT
                     ITTGTVATGTITTGTVLPARSAVPARATGYPPFTAPGKTLKLGAKGSVVKALQARLKEL
                     GYVPGSVDGRYGGATLTALWAFQKVQGITPTSTVAARTWRALENPRAPKVLVPRGKATR
                     VEVNLTKQVMVLYRGGVPVLISHISSGSGIPYTEYATWNGKRQRFSGSARTPTGDYKTT
                     WRVKGWHRSYLGQLYNPIFFNGGIALHGALSVPLYPASHGCVRLPMNVAELLPGMLGKG
                     VPVHVRGAFRR"
     misc_feature    complement(14336..14351)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 23.27"
                     /tool="antismash"
     misc_feature    14337..14350
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.72"
                     /tool="antismash"
     misc_feature    14338..14349
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.53"
                     /tool="antismash"
     misc_feature    14376..14391
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 25.49"
                     /tool="antismash"
     misc_feature    complement(14377..14390)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.0"
                     /tool="antismash"
     gene            14659..15099
                     /locus_tag="IEY80_RS14615"
                     /old_locus_tag="GCM10011574_29610"
     CDS             14659..15099
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889496.1"
                     /locus_tag="IEY80_RS14615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_29610"
                     /product="SAV_6107 family HEPN domain-containing protein"
                     /protein_id="WP_142568500.1"
                     /transl_table=11
                     /translation="MTEQNDDDHKSGPRLSQAVLAHLADARACLADATVGPTPADRYVS
                     AHLAALRAAAGILAARPRPMDGRRRRLRSAWELLPEAEPKLADWAAYFAVSAAKRAAAE
                     AGMVRSVTPNDAEEIIAEADRFVGEVESILGLPGRPTLPMAG"
     gene            complement(15223..16467)
                     /locus_tag="IEY80_RS14620"
                     /old_locus_tag="GCM10011574_29620"
     CDS             complement(15223..16467)
                     /EC_number="3.5.3.6"
                     /GO_function="GO:0016990 - arginine deiminase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006527 - arginine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016188925.1"
                     /locus_tag="IEY80_RS14620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_29620"
                     /product="arginine deiminase"
                     /protein_id="WP_142568502.1"
                     /transl_table=11
                     /translation="MTFHVGSEVGRLRQVLVDIPELALKRLTPGNKDGLLFDDVLWVHR
                     ALEEHREWCEVLAGRGVTVHHLGDLLREVIEIPDARKHILDGSVDEHWFGPLAADAIRN
                     TFDALDADALAPLLTGGITKREIMELGCDPGSIAFHTLGMDDFVLPPLPNHLFARDTSC
                     WVYDGVSINPMRKKARRRETVNYETVYRWHPLFAAGYDNPDAGGFNVWYEGVRMAPATI
                     EGGDVLVLGNGVVLVGVSERTQPQAVEMLATNLFRTGSAARIVALDLPKTRAFMHLDTV
                     MTNVDVGVFTKYAGLGMLPSYTVEPGDTDKELKVTDHPPEDMHKAIARALGLDDIKVLT
                     PTQDVHAAEREQWDDGCNVLALEPGVVVAYERNTTTNNHLRRHGIEVITIRGSELGRGR
                     GGPRCMSCPLERDPL"
     gene            complement(16678..17172)
                     /locus_tag="IEY80_RS14625"
                     /old_locus_tag="GCM10011574_29630"
     CDS             complement(16678..17172)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017622275.1"
                     /locus_tag="IEY80_RS14625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_29630"
                     /product="transcriptional regulator"
                     /protein_id="WP_030508976.1"
                     /transl_table=11
                     /translation="MPSDYAKSLGARLRAIRTQQGLSLHGVEEKSRGRWKAVVVGSYER
                     GDRAVTVQKLAELADFYGVPVSELLPGGAAPSPLAPAPKLVIDLERLSQLPKDKAGPLA
                     RYAATIQSQRGDYNGKVLSIRQEDLRSLAVIYDKSPVELTEEFIHWGVLDAEARRAVES
                     F"
     misc_feature    complement(17367..17382)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.71"
                     /tool="antismash"
     misc_feature    17499..17514
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.86"
                     /tool="antismash"
     misc_feature    17513..17528
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.5"
                     /tool="antismash"
     gene            17649..18206
                     /gene="pyrR"
                     /locus_tag="IEY80_RS14630"
                     /old_locus_tag="GCM10011574_29640"
     CDS             17649..18206
                     /EC_number="2.4.2.9"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131602.1"
                     /locus_tag="IEY80_RS14630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_29640"
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="WP_139574481.1"
                     /transl_table=11
                     /translation="MSDARNQARAVLEGPDIHRALTRIAHEILERTRGAESVVLLGIPT
                     RGATLAHRIAGRIAQFEGIKVPVGAIDVTMYRDDLRLRPARPLGRTELPPDGVDGRTVV
                     LVDDVLYSGRTVRAALDALNDVGRPRAVQLATLVDRGHRELPIRADYVGKNLPTSKSEK
                     VKVFLEETDGRDAVVLIKEDDR"
     gene            18203..19138
                     /locus_tag="IEY80_RS14635"
                     /old_locus_tag="GCM10011574_29650"
     CDS             18203..19138
                     /EC_number="2.1.3.2"
                     /GO_function="GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0016597 - amino acid binding [Evidence
                     IEA]"
                     /GO_process="GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1114: ornithine carbamoyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131603.1"
                     /locus_tag="IEY80_RS14635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_29650"
                     /product="aspartate carbamoyltransferase catalytic subunit"
                     /protein_id="WP_142568504.1"
                     /transl_table=11
                     /translation="MKRHLISTGDLTRDDALLILDTAEELARVSQRSIKKLPTLRGRTV
                     VNLFFEDSTRTRISFEAAAKRLSADVINFSAKGSSVSKGESLKDTALTLEAMGADAVVI
                     RHSASGAPHRLATWVRGSVVNAGDGTHEHPTQALLDAFSIRRRLGRLEGLKIAVVGDVL
                     HSRVARSNVLLLHTLGAEVTLVAPPTLLPVTVETWPCQISYDLDAVLPKSDVVMMLRVQ
                     LERMNAAYFPSAREYSRRYGLDRDRFARLHDDAIVMHPGPMNRGMEISAEVADSPRSTI
                     VEQVANGVTVRMAVLYLLLGGSEPAIGGAE"
     gene            19135..20466
                     /locus_tag="IEY80_RS14640"
                     /old_locus_tag="GCM10011574_29660"
     CDS             19135..20466
                     /EC_number="3.5.2.3"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011291502.1"
                     /locus_tag="IEY80_RS14640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_29660"
                     /product="dihydroorotase"
                     /protein_id="WP_223852711.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 4.1e-15, bitscore:
                     51.0, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTYDLHEGTVTTILIRGARILGGAPSDILLRDGVVADIGDLAGV
                     RADQTVDADGLIALPGLVDLHTHLREPGREDAETVETGTQAAARGGYTAVHAMANTSPV
                     ADTAGVVEQVWRLGQEYGHCDVQPVGAVTSGLGGSQLAELGAMADSAARVRVFSDDGKC
                     VSDAVLMRRALEYVKAFDGVVAQHAQEPRLTEGAQLNEGEVSARLGLIGWPAVAEEAII
                     ARDCLLAAHVGSRLHVCHVSTAGSVEIIRWAKSKGWDVTAEVTPHHLLLTDSCAERSPL
                     GPYNPIYKVNPPLRTAEDVRALREALADGTIDCVATDHAPHPVEDKETEWAAAAMGMIG
                     LETALSVVQEAMVETGLLDWAGVADRMSARPAAIGRLAGHGRPVEPGAPGNLTLFDPSV
                     RQPVDPAAMASKSRNTPYEGLTLPGRVVATFLRGRPTVLEGKLV"
ORIGIN
        1 ggccctgcgg ccctacgacg agccgctggc ggccgaggag tccgccgacc tcggcgacct
       61 gccgctgctg cccgggctgg tcgactccca cgtgcacgtc aacgagcccg gccgcaccca
      121 ctgggagggc ttcgcgaccg ccaccagggc ggcggcggcc gggggcgtga ccacgatcgt
      181 ggacatgccg ctcaactcgc tgccgccgac cgtggacgtg gcggcgctgg aggtcaaacg
      241 gaaggccgcc gagggccggt gccacgtcga cacgggcttc tggggcggcg cgatccccgg
      301 caacctcgcc gacctgcggc ccctgcacga ggccggggcg atgggcgtca agtgcttcct
      361 gtccccgtcc ggagtggacg agttccccgc gctcgaccgc gacgggcttc gggccgcgct
      421 ggcggaggtg gccgccttcg acggcctgct gatcgcgcac gccgaggacc cggggctgct
      481 gtccgacccc ggcggccccg cgtacggcga cttcctcagg tcccgcccgc aggaggccga
      541 gcgccgggcg gtcgagcagg tgatcgccct cgcggcggag acgggcgcgc gggcccacat
      601 cgtgcacgtg tcggccgccg cctgcgtcga accgctgcgc gcggcccagg cggccggggt
      661 gcgcgtcagc gccgagacct gcccgcacta tttgaccctg gcggccgagc aggtcaccgg
      721 gcccgcctac aagtgctgcc cgccgatccg ggaggccgcc aaccgcgacg ccctgtggca
      781 ggcgctggcc gacggcgtgc tcatggggat cgtctccgac cactccccgt cgacgcccga
      841 cctcaaggtg cccgacttcg ccgccgcctg gggcggcatc tcctcgctcc aggtcggcct
      901 gcccgccgtg tggaccgcgg cacgcgcccg cgggcacggc ctggccgacg tggcgcgctg
      961 gatggccgag ggaccggccc gcctggccgg cctgccccgc aagggggcga tcagggaggg
     1021 cgacgacgcc gacctcgtcg ccttcgaccc cgacgccgag ttcacggtgg acgtcgcggc
     1081 gctgcaccac cgcaacccgg tgtcccccta ccacggcgcg cggctggcgg gcgtggtgcg
     1141 caccacctgg ctgcgcggca cacccgtcga cttcgacacc ccgcgcggcc ggctgctgac
     1201 gaggggagcc cgatgaccgg cttcacccgc ctacccgacc tcgccctgcg cacgtacggc
     1261 gggtcggtcg tggccgccaa cgacgagtcg ttcgccgaac gggaggccct tatccggccg
     1321 ggaccggccg agttccggcc gcacaccttc ggggccaagg gccaggtcta cgacggctgg
     1381 gagaccaggc ggcggcgcga gcccggccac gactgggcga tcgtgcggct aggcctgccc
     1441 gggatcatca ggggcgtggt cgtggacacc gcgtggttcc gcggaaacta cccgccgtac
     1501 gcgtcggtcg aggcgtgcgc ggccgagggc catcccgcgc cggacgagct ggacggctgg
     1561 gtggagatcg tgccgaagag cccgctgaag ggcgacacgg tccacgagtt cgccgtgacc
     1621 gacccccgcc gcttcaccca tgtgcggctg aacatcttcc ccgacggcgg cgtcgcccgg
     1681 ctgcgggtcc acgggcgggt ggtgcccgac cggacgttcc tggagggcct caccgtcgac
     1741 ctcgccgcgc tcgagaacgg cggactggtg acggcgtgct ccgacgagtt ctactcctcg
     1801 ccgaacaacg tcctcgcgcc cggcctggcc cgcaaccagg ccgagggctg ggagaccgcc
     1861 cgccgccgcg acggcggcaa cgactggctc gtcgtcgccc tggccggtcc cggccgggtg
     1921 gccgtcgccg agctcgacac gaccaacctg gtgttcaacg cccccggctg ggtgtcgctc
     1981 aagggcgtgg acgcggaccg ggcgccgctg gaggacgagg acgcctggtt cccgctgctt
     2041 cccatgacgc gcctgcagcc cgacacccgc caccgcttcc gtctcgacga cgaccgccgg
     2101 atcacccacg cccggctcga catccacccc gacggcggcc tcgcccgcct ccgcctcctc
     2161 ggcaccctcg ccccctggtc cccgccctga cgtcgggctt gacgattcac gctcagtgaa
     2221 gtgttttctg cggggtgctc gcggaggatc acgaccgctg cgcggcgtac cggcggacga
     2281 ccggttccag gtagtcggcg tggggcccgc tgagccgcgc gagctcggcg ggggagcgga
     2341 cgaggcggag ccggccgcgc tccgcaccgg ggagcggcct cggagaactc cgcgaccggt
     2401 acggcggcgg gaacgcccgt cctgggcgtc agtgccagat cgtgatggtg gcgcccggcg
     2461 gctgctggcc gagcggattc tcgccgacca cgcggtcggt gcccaccatc ttgcgggtct
     2521 tgacgttgaa gccggccgcc ttcagctcgt tcaccgcgtc cttcaccgac ttgaacatca
     2581 cgttgggcac gttgacgacg gcgggcgggc tctggccggg gtcggcggga ttgacctccc
     2641 acggccagtg gaagccctgg tccggtccgc gcgaggcggt cagatggacg gtccccccgg
     2701 ccacgacctc ggcgcccccg ggagggtcct gcgcgatcac ggtgcccggc ggggtgtcgt
     2761 cggtggtctc gtcgatctgg acgttgaagc ccttctcccg caggaacttc tccgcctggt
     2821 cgcgcatcat ctgcgtgacg tccggcatca gcagcccggc gctgaccacg aagttgaccg
     2881 tgctgccctt cttgacgcgc ttgcccaccg gcgggttggt tcggatgacc tgatcgcggg
     2941 ggacggtgtc gctcgcgctc ttgctcaccc gtccgggggt caggccggcg tcggcgatct
     3001 tcgcccgggc gtccgccagg ctgacgttct cgaccttcgg cacggggaca gtctccgggc
     3061 cggccgacgg gatgagggtg agcaccgagc ccttgaccac ctcggcgccc agtcccggat
     3121 cggtgtccag gacgatgtcc ttcggcacct tgtcgtcgaa ccgcgcctca ccgatcctga
     3181 cctcgaaacc ggcctgctgc gcggcctgcc tggcgaccgt gacgggcttg ttcaccaggt
     3241 cggggacctt cgtgtagcgg ccctgggaga accaccagcc ggtgaaggcg acgcccgcca
     3301 gcatgacgag ggccagcgcg gcgacgaacc agacgggcct gatcccgcgc cggcggcggc
     3361 gccccgcctc ggcgcggccg gtcagcagtt ccgagcgcgg ctggatcatc gtccggtcgg
     3421 ccggcggctc gtgctccggg cgcgcgtgct gcgccgtgcc gaacggggag gacccgccgg
     3481 gcggcgggag ggtccgatgc gcgcccgtcc gcaccccgct gtgggcaccg ctgtcgtagg
     3541 ttccgtgggg ggttccgtgc ggggctccgt ggagggcgga gtgcgcgccg gtgtgcccgg
     3601 tcctgggcag cgtacggtgg atctcgacgg ccgcgacgag catggcggtc gcgtccgccg
     3661 ggcgcgcggc ggggtccttg tcggtggccg cggcgacgag cgcgtcgatc gacggcggca
     3721 cgtcggccac cgacagcgac ggcgctggga cggtctcgtg cacgtgccgg taggcgaccg
     3781 acatcggcgt ctcgcccgcg tacggctgcc gtccggtgag cagctcgaac agcatgatcc
     3841 cggcggcgta cacgtcgctt cgtgcgtcgg ccgtgccggt cgtgacctgc tcgggcgaca
     3901 tgtagccgat cgtgccgatc atcatgccgg tcttggtctg gttggtcgcc tcgatcgcgc
     3961 gggccaggcc gaagtccacg accttcaccc ggccgtcgtc ggcgagcagc acgttctcgg
     4021 gcttgacgtc gcggtggatg agcccggcct ggtgggccgc gccgagggcg gcgagcaccg
     4081 ggatgaccat ctccagggcc tcgcgcgccg ggacgtgacc gcgcttgcgc aggacgtcgc
     4141 gcagcgtcct gccggggacg tactccatcg acaggtagac attcgccccg tcggtgccct
     4201 ggtcgaagac ctgcacgatg ttggggtgcg agaggctggc caccgacttg gcctcgccga
     4261 tgaaccgccg cacgaactgc gggtcctcgg ccagggagcg gtgcatcacc ttgacggcga
     4321 ccgtgcggtc gagccggacg tccagagcca ggtagacgga ggccatgccg ccccgggcga
     4381 tccgggactc gacgcggtag cgcccgtcga gcacctgccc cacgagcggg tcggttagcg
     4441 tcgtgtccac ccgccagagt ttacgggtga tttgccgccc ggcgtgttcc cgaatcccaa
     4501 accgagacct attcgggcgc ggtccgaggc gtccgaaaag ccgtgccgat ttggaaaacc
     4561 ggccttacca gacgcgggtt tcgcgccttc ccgcccggcc cgcgaagggt ccggaacggg
     4621 cgggaaggac ggtggcgggt tcaggacgtg cgggcggggg aggacgcctc ggcgtagcgg
     4681 cggcggggga tgcgcccggc gaggcgggcc agccggcccg ccgtgaccgc ctgccgcatg
     4741 gccgcggcca tcaggccggg ccggtgcgcc cgggtcacgg cgctggccag cagcaccgcg
     4801 tcgcagccca gttccatcgc cagcgcggcg tcgctggccg tgccgatgcc ggcgtcgagg
     4861 atcaccggca ccgtggcggc ctcgacgatc agctcgatgc tgtgcgggtt gcggatgccc
     4921 agcccggagc cgatgggggc gccgagcggc attacggcgg cgcacccggc gtcctggagc
     4981 ctgcgggcca gcgccgggtc gtcgccgatg tacggcagca ccgtgaaacc gtcggcgacc
     5041 agccgttcgg cggcgtcgaa ggtctcgatc gggtcgggca gcagggtccg ctcgtccgcg
     5101 atgacctcca gcttgaccca gtcggtctcc agcgcctcgc gggccaggcg ggcggtcagc
     5161 accgcctccc cggcggtgaa gcaccccgcc gtgttcggca gcaccttgat gccgcgggag
     5221 cgcagcacgt cgagcaccga gccgcgggac tcaggatcga gcctgcgcat cgcgacggtc
     5281 gtcagctcgg tgccggacgc ctccagcgcc tggtcgagca cctcgagcga cggcgcgccg
     5341 ccggtgccca tgacgagccg cgaggtgaac ttctccccgc ccagcacgaa gacgtcgtcg
     5401 gtcatgctca ccctccctgc acggccgtga gcacctcgac gccgtcgccg tcggcgaccg
     5461 gggtcgtgtc ccaggcgctc cggctcacga cttcgccgtt cagcgccgcc gcgaccccgg
     5521 atgtgaggga cgtgagggtc cgtacggcgt cgccgatcgt ggcgccgtcc ggcagttcgg
     5581 ccgcgcctcc gttgatcgtg actttcattg actgaatctc cctggatcgc agaaccgggc
     5641 gaccgggggc acctcgtcgc cggtgaggaa cgcggcgacg gcgtcggcgg tgatcgggga
     5701 cagcagcacc ccgttgcgtc cgtgcccggt cgccgcgagc acgccgggcg gcccggccgg
     5761 gccgatgatc ggcaggttgt cgggcgtgcc gggccggaag ccggtcgtcg tctcggccag
     5821 ttcgagctcc gtgatgccgg gcaccagctc gcgggcgtcg cgcagcagct cgtacacgcc
     5881 tccggcggtg accctcgggt cgaaccccat ctcctgggtc gtggcgccca cggtgatctc
     5941 tccgtcgccc cgggggacca ggtaggcggg ggagccgtgc accagtcccc tgacgcaccg
     6001 ggtgaggaag ccacggggcc cgcgcagccg gaggatctcg cccttgaccg ggcgcaccgg
     6061 caggctgggc agcagggacg ccgaccacga cccggccgcc acgacgacct ggccggccgc
     6121 gatgacgccg ccggactcca gccgtacgca cggagcgccg gggcccgggg cgtcgatccc
     6181 ggcgacgcgc tcggtcacca gcgtgccgcc cgccttctcg aacgccgtga ggagggcgcg
     6241 cacgaccctg cgggggttga cccacgcgtc gtcgcgggcc agcagcccac cgcgtacgga
     6301 gggggagagc atcggctcgt aggagcggca ctcgcgcccg gtgagccgct cgacccgcag
     6361 accgagcgtc cgctcgaagg ccgcgaggtc gtcgaggacg gccatgtcgt ccgcgccgcg
     6421 ggcgacctcc agcgtgccct cggtccggta gtcgaggtcg tcgccggtct cgtcctccag
     6481 ctccgcccgg aacgccggcc aggccgccag cgacgcgagg ccgagccgca gcagcggctc
     6541 ttccgtgtag gtcacctcgc tgaccggcgc gagcatcccg gcggaggcgt gagtggcgcc
     6601 gcctccgggc gcggggtcca ccaccgccgc cgacaggccc cgccgggcgg tgcgccaggc
     6661 cgcggccagg ccctccaccc cgccgccgac gatcacgacg tcgtagccgg accggactcc
     6721 ggacggcggt gtgcgggaca cagcgctccc ttcgccggca ttacccggat caggtcgggg
     6781 cggtcgagag cctcacgctc tcctctcagc ccggtccgcc gggctcccgc gcgtcttact
     6841 cccacaaggg tagtacgccg cccataacgg ccgatcgccg gaccggcggg tgcggagccg
     6901 cccgcaggcg catgatggcg cgacgtggat cgactcgacg gaggtatgcc atggccacgc
     6961 tgctctactc ggccaccatg tccctggacg gcttcatcgc cgggccggac ggcgacatgt
     7021 cctggctgac cgaacatctc ggacccaacc cggacgtgga cgggctggtc ggcgacatcg
     7081 gcgcgctgct cgtcggcaac cgcaccttcc ggggtgacga tccgaatcgc ggcacctcgc
     7141 aggagggcgc gttcggcggc gtgtggagcg ggccgcagtt cgtgctcacc cacgacctcc
     7201 cggccgcgcc ggtgcccggc gtgaccttcg tgacggacct cggcgcggcc gtcgaggcgg
     7261 ccacggcggc cgccggggac aagtacgtca acatgctcgg cgccgacgtc gccgcgcagt
     7321 gcctcgacgc gggcctgctc gacgagatcc tcgtgtgcgt ggcgccggtc atgctcggcg
     7381 acggcgtccg gctgttctcc cgccccggcg gcgaccgcgt ccggctcgaa cggatcagcc
     7441 tcacgcacgt gccgcacgcc acgaacatct ggatgcgcgt ggtccggtag aacgccggtg
     7501 aggatccggc gtccttcaca acgcgggccc cggcataagt gcgcgtcaat tgcccaactc
     7561 gttatgaggg gcccgttggc cagggccccc gttcacaatc tatggtcaag ctgtggatca
     7621 cgtcgtggtg gtgggtgccg gcctggccgg cgtgcgaagc atcgaggcgt tgagggccgg
     7681 tggattcacc ggccgcatca cgctcatcgg cgaggaacac catcgcccct atgaccggcc
     7741 gccgctgtcg aaggcggtgc tgctcggaga gaccgactcc accgtggtcg actccgatct
     7801 cgacgccctc gacgtgcggc tgtgcctcgg cacggcggcc aagggcctgc gcgacggcgt
     7861 gctggagacg accgagggcg agctggagta cgacggcctg gtcatcgcca ccggcgccac
     7921 gccgatccgc ctgcgcggag agggccgcca gcacgtgctg cgcacgatcg aggacgcgct
     7981 cacgcttcgt gagcggctgg tccccggcgc ccgcgtggcc gtcgtcgggg ccggctggat
     8041 cggcgccgag gtcgccaccg cggcggccag ggcgggctgc gcggtgaccg tggtggaggc
     8101 gggggagagc ccgctcgcgg tggcgctcgg gcccgccgtg ggcagccaca ccaccgactg
     8161 gtacgcgcgg gcgggcgtcg agctgcgcct cggcgcgatg gtcggcaccg tggacgccga
     8221 cggtctcacg ctcatgtccg gcgcccgggt gccggccgac gtggtcgtca ccggcatcgg
     8281 cgtgcgcccg gccgtcgact ggctgaaggg gtcggcggtc cggctcgacg acggggtggt
     8341 ggtcgacgag cacctgcgca cgtcgctgcc caacgtggtc gcggtgggcg actgcgcgaa
     8401 ctggtggtcg cgcaggttcc acgcccggct gcgggtcgaa cactgggaca ccgcgcttca
     8461 ggcccccgac acggccgccg ccaccctgct gggtgaggag gcggtctacg accccgtgcc
     8521 gtacttctgg tccgagcagt tcggtcacat ggtgcagttc gccggtcatc gggacgccgg
     8581 cgaccgcatg gtgctgcgcg gcgacccgcg cagggacccg aagtggtcgg tgtgctggct
     8641 gacggccgac gaccggctcg ccgcggtgct caccgtcgac cggccgcgcg acgtggtgca
     8701 gggtcgcaag atcgtcgaaa gtggccggcg gctcgatccc ctgcgggtcg cggacgcggc
     8761 cgtggcgctt cgcgactgca ttatggccta atcgaggtgt atccccggag ctcgtgtgtg
     8821 gtaatggtgg acccgtgacg cttactgttg cgaagatcga ccgggagacc gaccagctcg
     8881 taggggagtg gctccccctc tcggaggccg ccgagaagct ggtgctcagc atcggccgcg
     8941 ccaagcaact cctcaaggac aagaagctcg tcggcgtccg gcggggcggc ggcgagccgc
     9001 agatcccggc ggtgttcatc gcggacggcg aggtgctcaa gggcctgccc ggcacgctca
     9061 cggtcctggc cgacgccggg tacgacgagg tggagtcgat ccggtggctg ttcaccccgg
     9121 acgactcgct accggggtcc ccgatcgacg cgatcgtggg gggccggcac accgaggtca
     9181 agcgcagggc ccaggccctg ggcttctgac ccctccggcg cgtggcattg tggtcgggtg
     9241 aacgacatcc ggcgacagcg gctcgcgcag gccaggctct acctctgcac tgacggcagg
     9301 aggggccgcg gcgacctgga gaagttcctc gacgcggtcc tgtccgccgg ggtggacatc
     9361 gtccagctca gggagaaggg cctggaggcg cgcgaggagc tggacctgct ggaggtcttc
     9421 cgcgcggcct gcgacaggca cggtgcgctg ctcgcggtca acgaccgggc ggatgtggcc
     9481 tacgccgccc ggcccgacat cctgcacctc gggcaggacg atctcccggt cccggtggcc
     9541 cgggagatcc tcggtccgga tgtcctgatc ggcaggtcca cgcactcggc ggccgaggcg
     9601 tcggccgcgg ccgtgcagcc gggggtggac tacttctgct gcggcccgat ctggcccacg
     9661 cccaccaagc ccggccgtcc ggcgcccggc cccgcgctgc tggagcacgc cgcgcgcctg
     9721 ggcgccgacc ggccgtggtt cggcatcggc ggcatcggcc cggacaacct cgacgaggtg
     9781 atggcgcacg gcgtgcgccg cgccgtggtc gtccgggccg tcaccgaggc cgacgacccc
     9841 ggcgccgccg ccgcagcgct caaggcccgg ctgtcggccg tcccgctctg atcggaacgg
     9901 cctcctccgg gcccgtccgg ccggcgcccg cgacgcggcc cggtggcgtc gacgcggagc
     9961 cgtccactca tgtcgcggcc ggtccggccg gcgcctcgcg tcaggtgcgg cgggacgtgg
    10021 cggccacggc cagggcggcc agtgccgtgc gggcctcttc ctcgatcggc gcctggtcga
    10081 gggcgtgcag cgcgtcgtcg aggtagcgct tgatcatgcc ttcgcacgcg gccagcgcgc
    10141 cggtctcctc gatcaccgtc cggagctgcg cgaccccctc ggcgtccagc gcggggtcgc
    10201 cgagcaggga gcgtacgacc gcggtctggg cgggggtggc cgaggcgagc gcacgcgcga
    10261 tcagcacggt ccgcttgccc tcgcgtaggt cgtccccggc gggcttgccg gtctccgccg
    10321 ggtcgccgaa cacgccgagg atgtcgtcgc ggagctggaa ggcgatgccc acctgctggc
    10381 cgtactgcac gcagagccgg tcgatccagg cgtgcgaagc ctgggcggcg aggacgagcc
    10441 cgagcctgag cggctgctcg accgagtatt tgccgctctt gtacagcgcc acccgcagcg
    10501 cgctgtcgaa cgtgctctcg ccctgcgcct gttcgagcag gtcgaggtac tgcccgcaca
    10561 tcagctcggt gagcatgtaa tcgtgcagcg gctgggcggc ggcgatcgcc tcgggcgcca
    10621 ggccgctggt gcgccacatc tccccggacc acaccaggag caggttgccc agcagcacgg
    10681 ccgtgccctc gccgaactgc cgtccggagc cgtgccagcc cgcctcggcg tgcatccgct
    10741 cgaaccggcg gtgtgccgac ggcatgcccc ggcgcacgtc gctcgcgtcc atgacgtcgt
    10801 cgtggatgag cgcgctggcc tggaggagtt ccagcgaggc ggcggcgacg tgcagtcccg
    10861 ggtcgtcgcc tccgccggcg gcccgccagc cccagtggca gaaggcgggg cgcagccttt
    10921 tgccgcccgc tatgaagtcc tccgcggcgg acagcagggc ggccagatga gggtcactga
    10981 agtgtggtcg ctgccggtcg aggaagtccc ggagcgcgcg gtccacctcc gtacggatgg
    11041 aatcgagcga ggcggcggaa gcggtcatac tgagagacta accggggttg atccggtcac
    11101 ccagcagcag atcccatcca agtgggccaa ctcgccctca taggacaaat gtccacatag
    11161 caagaccgcg agggcggcga aaaccgctat cgctgtaccc ttgccggtat ggctctcggt
    11221 ctgccctcgc ggcttcctga tcgcgtcccg acggtccgcg aactgctggc cgcgggcgag
    11281 cgctcgttct cgttcgagtt cctcccaccg aagaccgacg agggggagcg ccagctgtgg
    11341 cgggcgatcc gcgagctgga agcgctgcgg ccgacgttcg tctccgtgac ctacggcgcc
    11401 ggcggctcga cccgggaccg tacggtggac atcgtcgagc ggctggcgca cgagacgacg
    11461 ctcacccccg tcgcccactt caccgcggtc gaccactcga tccgcgagct gcgccacctc
    11521 gtcggcaggt tcgccgacgc gggcgtgcgc aacatcctcg ccgtacgcgg cgacccgcgc
    11581 ggcggcaacc cgctggacga gtgggtgaag cacccggagg gcgtccttta cgccgaggag
    11641 ctggtgcggc tgatccgcca ggcgggggac ttctgcgtgg gagtggccgc cttcccctac
    11701 aagcacccca ggtcggcgac catcgagtcg gacaccgagt acttcgtgca gaagtgccgg
    11761 gccggcgcgg actacgcgat cacccagatg ttcttcgagg cggacgacta cctgcggctg
    11821 cgtgaccgcg tggccgcccg cgggtgcgac accccgatca tccccggcat catgcccgtg
    11881 acgcagatga gcacgatcgc ccggtcggag cagctgtccg gtgcgccgtt cccgccggag
    11941 ttggccgagc ggttcgcggc cgtcgccgac gacccggccg cggtccgtcg cctcgggatc
    12001 gagcacgcca tcgagatgtg ccggaagctt ctcgacgagg gcgctcccgg catccacttc
    12061 atcaccttca accggtcgag cgcgacccgc gaggtgttcc aggcgctgca cggcgtgccc
    12121 gccgccgtgg ccggctgagc cggccggtcc cgatcagcct tcgagggccg cgccctcggg
    12181 cagcggcagt ggcagccgca cccctgcgat gacgtactcc tcgtaaccgc ccgggaagac
    12241 gaaccgggtc atcaggtcgg cgaacccgac gtcccggtag aggtgccggg ccacggtggg
    12301 ggcgtcgtgc gtcgacagca cggccgtgcg ctccgggcgg ccctcgcaca gcgtgtggat
    12361 cagtcgccgg ccgattcccc ggccctggta ctcggggcgc acgtggatct cggcgatctc
    12421 cagggcgtcg ccgaaccagg cgttcgccac caccggcccg gcccggtcct gcagcgcccc
    12481 gcgtacgacc tcgtgccacc actgcccctg gccgccgtgg aagccgtacg cgaagccggc
    12541 gacaccggag gcctgcgtgt cctcggcgag cacgcagtcg aagtcgggat aggtggcgtg
    12601 gttgcgcatg atcgccatgc ggcccgcgag ctggtccgac ggcgggcgca tggcgaccgc
    12661 gtagatctcc agcacggtgt ccagtgccgc cctgaactcg tcgggcccca cccgtcgcag
    12721 ttggatcact cgtcgcacac tagcaaaacg acgccgggct ggtccggcag cgtcactcca
    12781 cctcggcggc cgtgcccccg gtggtgcgca gcagttcgtc gtaggacgtg gggaagacgg
    12841 tgtgggggtg ccccgcggcg gcccacacca cgtcgtgctt gctcagccag gtgtccacca
    12901 gcgtgcgcac gggcgcgggg tgcccgaccg gggcgacacc gccgatgggc tgcccggtgt
    12961 gctcgcggac gaactccgga gtggcccgcc gcaccttcgc cgcgccgacg agccgcgcga
    13021 tcagatcggt gttcacccgg tgggcgccgc tggtcagcac cagcaacggc gcgccgtccg
    13081 cgtcgaagat caggctgttg gcgatcgcgc cgacctcgca gcccagctgg gccgcggccg
    13141 tggcggccgt cggggcggcc tcgtcgagca cgacgacctc gcccgtcacc gcgtgggccc
    13201 gcagggcctc ctgaacgcgg acgacgttcg gatgcaactt ttctgccacc cggtcactct
    13261 aaacggattg ccaggacata cgcggccgat tatggccact tacgatcacg cggctcacaa
    13321 tcggaccgta aggtaagtcc tttgatcgag aagcgggctt atgagggggt tggtcatgat
    13381 gaggggtaga cggcgactgc tcgtcgtggc gggggcggcg acgttcgcga ccgccttcgc
    13441 ggttgccggc gtgagcggcc cggcgcaggc gcgcgccgcc gcgccgacgg ggaccgtcgc
    13501 caccgggacc ataaccacgg ggaccgtcgc caccgggacc atcaccacgg ggaccgtgct
    13561 cccggcgcga agcgccgtcc ccgcccgcgc cacgggttat ccgccgttca ccgccccggg
    13621 caagacgctc aagctcggcg ccaagggctc ggtcgtgaag gcgctgcagg cccggctgaa
    13681 ggagctcggg tacgtgcccg gcagcgtcga cggccggtac ggcggggcca cgctgacggc
    13741 tctctgggcg ttccagaagg tgcaggggat cacgccgacc agcacggtcg ccgcccgcac
    13801 ctggagggcg ctggagaacc cccgcgcgcc caaggtcctg gtgcccaggg gcaaggcgac
    13861 ccgcgtcgag gtgaacctga ccaagcaggt gatggttctg taccggggcg gcgtgccggt
    13921 gttgatcagc cacatctcca gcggcagcgg catcccctac accgagtacg ccacctggaa
    13981 cggcaagcgg cagcggttct ccggcagcgc ccgcacgccg accggcgact acaagaccac
    14041 ctggcgggtc aagggctggc accggtccta cctcgggcag ctctacaacc ccatcttctt
    14101 caacggcggc atcgcgctcc acggcgcgct gtcggtgccg ctctacccgg cgtcgcacgg
    14161 ctgcgtgcgg ctgccgatga acgtggcgga gcttctgccg ggcatgctcg gcaagggcgt
    14221 tcccgtgcac gtcaggggcg ccttcaggcg ctgacgccgg ctccggaggg gccccgcgcg
    14281 agatggtcgt gcggggcccc tccgccgttc gcggccggcg tttcgaacgc gatcctcgaa
    14341 cacgtattcg ttgacagcct tgacaggtgg cggggtcgaa tctatgttcg atggggtggg
    14401 cgtgggactc gcggctcgcg cccaccccgt tggactcgtg ccttcgtcgt cggcggagac
    14461 ggatgcggca cggcctgcgg cgtgggccgg acggggagag gggaagctcc tcgtccggcc
    14521 gcccacggga gcctgagaat gcgtcgggcg atctcgagcg gttcacggga tctcccggcc
    14581 ggcgaaattg tcggtgcgat ctgcgactgt gaagtcaccg gcgacttcgc cggagtgcca
    14641 cgactcaagg aggcgggcat gaccgagcag aacgacgacg atcacaagag cgggccccgg
    14701 ctctcgcagg cggttctggc acacctcgcg gacgccaggg catgcctcgc ggacgccacc
    14761 gtcgggccca ctcccgcgga ccgctacgtg tcggcccacc tggcggccct ccgtgcggcc
    14821 gccgggatcc tcgcggctcg tccgcggccg atggacggcc gcaggcggcg gctgcgcagc
    14881 gcctgggagc tgctgccgga ggccgagccc aagctcgcgg actgggcggc ctacttcgcg
    14941 gtgagcgcgg ccaagcgtgc ggcggccgag gccggcatgg tccggtccgt cacgccgaac
    15001 gacgcagagg agatcatagc ggaggcggac aggttcgtcg gcgaggtcga gtcgatcctc
    15061 ggcctgcccg gccgtcccac tctgcccatg gccggctgac ctccgtcccc gcccttgatc
    15121 ccgcgcgccc gttcagcatg gccgtggacg gtgatcggac ggagacggtg atcggacgga
    15181 gacggtgatc ggcaggggac ggtgatcaga tggcgacggt gatcagaggg ggtcgcgctc
    15241 cagcgggcag ctcatgcacc gcggcccgcc gcgtccgcgg ccgagctcgc tgccccggat
    15301 cgtgatgacc tcgatgccgt gcctgcgcag gtggttgttg gtcgtggtgt tgcgctcgta
    15361 ggccacgacc acgccgggtt ccagcgccag cacgttgcag ccgtcgtccc actgctcgcg
    15421 ctcggccgcg tgcacgtcct gcgtcggcgt gaggaccttg atgtcgtcga ggccgagggc
    15481 ccgcgcgatc gccttgtgca tgtcctccgg cgggtggtcg gtgaccttca gctccttgtc
    15541 ggtgtcgccc ggctccaccg tgtacgacgg gagcatgccg agcccggcgt acttggtgaa
    15601 cacgcccacg tcgacgttgg tcatcacggt gtcgaggtgc atgaacgcgc gggtcttggg
    15661 caggtcgagc gccacgatgc gggccgccga ccccgtccgg aacaggttgg tcgccagcat
    15721 ctccacggcc tgcggctggg tgcgctcgct caccccgacg agcacgacgc cgttgccgag
    15781 caccaggacg tcgccgccct cgatggtggc cggggccatg cgcacgccct cgtaccagac
    15841 gttgaacccg ccggcgtcgg ggttgtcgta gcccgcggcg aacagcgggt gccaccggta
    15901 gaccgtctcg tagttgacgg tctcccgcct gcgcgccttc ttccgcatcg ggttgatcga
    15961 caccccgtcg tacacccagc aggaggtgtc gcgggcgaac aggtggttgg gcagcggcgg
    16021 gaggacgaag tcgtccatgc cgagggtgtg gaacgcgatg gagccggggt cgcagcccag
    16081 ctccatgatc tcgcgtttgg tgatcccgcc ggtcagcagg ggcgcgagcg cgtccgcgtc
    16141 gagggcgtcg aacgtgttgc ggatcgcgtc ggcggccagg gggccgaacc agtgctcgtc
    16201 gacgctgccg tcgaggatgt gcttgcgcgc gtcggggatc tcgatgacct cccgcaggag
    16261 atcgccgagg tggtgcaccg tgacgccgcg cccggcgagc acctcgcacc actcccggtg
    16321 ctcctccagc gcgcggtgca cccacagcac gtcgtcgaac agcaggccgt ccttgttgcc
    16381 cggggtgagc cgcttgagcg cgagttcggg tatgtcgacc aggacctggc gaagcctgcc
    16441 cacctcggag cccacgtgaa acgtcatgtc ctgcctatcc ccgcgtggcg gcaatcactc
    16501 gtcaccggcg gctctccgtt gccggagcgt cgccggtggc gaggcggtgc ctgacgccgc
    16561 ccggcgcgag cgcgggccac gcgccgcagg gcctggtccg tcaggcgcga cagacacgag
    16621 gggagccggg caggacggac gtcggcgcgg ggagccgcgc gcgaaccggg cggaaggtca
    16681 gaaggactcg acggcgcggc gggcctcggc gtcgagcacg ccccagtgga tgaactcctc
    16741 ggtcagctcg accggcgact tgtcatagat gaccgcgagc gagcgcaggt cctcctgccg
    16801 gatggacagc accttgccgt tgtagtcgcc ccgctggctc tgaatggtgg cggcgtaacg
    16861 ggcaagcggg ccggccttgt ccttcggcag ctgtgacagc cgctccaggt cgatgaccag
    16921 cttgggagcg ggcgcaagcg ggctcggagc ggctccgccc ggaagaagct ccgacaccgg
    16981 cactccgtag aaatccgcga gctcggcgag cttctgcacg gtcaccgcgc ggtcgccgcg
    17041 ctcgtaggag cccacgacga cggccttcca ccgtccgcgg gacttctcct ccacaccgtg
    17101 cagggacagc ccctgctggg tccggattgc gcgcaggcgc gcgcccagcg acttggcgta
    17161 gtcagacggc atcgtgtggc ccccggcttt ctatggctct tctcacttga ttgtgcgtcc
    17221 ttgtcccaag cgttccgaac accggggctg gtgcccgtga ccggcacctt cggtgaccgc
    17281 tgcgtcgggt tttacccagg aaggtcgcgt gttgtggtta cggacagtga cggtaaagcc
    17341 gacactccca aaggtcaagc tgattggaaa aaagagcgtc aaacagtgct ctcaccgaaa
    17401 tcaccgacac cggcgtgatg tggcttccga tccccggccc gccctccgaa cgtcccggaa
    17461 cgtcaccgga agattcccga aggtccccga agacccccgg cacgtcctcg tcacgccgag
    17521 ggcgagcggc tcctccgcgg gcatcacccc tggcgggagg ggggttcgca gacggtcctg
    17581 atactctaag cacaaccgac acccttttaa gacccgtcca gtgaggcggg aaaggcggtg
    17641 actttttcat gtctgatgcc cgaaatcagg cccgtgccgt tctggagggg cccgacatcc
    17701 atcgggcgct cacccggatc gcgcacgaga tcctcgaacg caccaggggc gcggagagcg
    17761 tcgtcctgct cggcatcccc acccgcggcg ccaccctcgc gcaccgcatc gccgggcgca
    17821 tcgcccagtt cgaaggaatc aaggtccccg tcggggccat cgacgtcacg atgtaccgcg
    17881 acgatctgcg cctgcggccc gcgcgcccgc tcggccgcac cgaactgccc ccggacggcg
    17941 tggacggcag gaccgtcgtc ctcgtggacg acgtcctcta ctccggccgc accgtgcgcg
    18001 ccgcgctcga cgcgctgaac gacgtgggca ggcccagggc cgtccagctc gccacgctcg
    18061 tcgaccgcgg ccaccgggag ctgccgatcc gcgccgacta cgtcggcaag aacctgccga
    18121 catccaagag cgagaaggtc aaggtcttcc tggaggagac ggacgggcgc gacgcggtcg
    18181 tgctcatcaa ggaggacgac cgatgaagcg tcacctgatc tcgaccggcg acctcacccg
    18241 cgacgacgcg ctcctcatcc tcgacacggc cgaggagctg gcgcgggtct cgcagaggtc
    18301 catcaagaag ctgccgacgc tgcgcggccg cactgtggtg aacctcttct tcgaggactc
    18361 cacccggacc cgcatctcct tcgaggccgc ggccaagcgc ctgtcggccg acgtgatcaa
    18421 cttctcggcc aaggggtcga gcgtgtccaa gggcgagtcg ctgaaggaca ccgcgctcac
    18481 cctggaggcc atgggcgccg acgccgtggt gatccggcac agcgcctcgg gcgcgccgca
    18541 ccgcctggcc acctgggtgc gcggcagcgt ggtcaacgcc ggggacggca cccacgagca
    18601 ccccacccag gcgctgctcg acgccttcag catccgccgc cggctgggcc ggctggaggg
    18661 cctgaagatc gccgtcgtgg gcgacgtgct gcacagccgg gtcgcccggt ccaacgtgct
    18721 gctgctgcac acgctcggcg cggaggtgac gctggtcgcg ccgccgaccc tgctgccggt
    18781 gacggtcgag acctggccct gccagatctc gtacgacctc gacgccgtgc tgcccaagtc
    18841 ggacgtcgtg atgatgctgc gggtccagct cgaacggatg aacgcggcct acttcccctc
    18901 ggcgcgggag tacagccgcc gctacggcct cgaccgcgac cgcttcgccc gcctgcacga
    18961 cgacgccatc gtcatgcacc ccggcccgat gaaccgcggc atggagatct ccgcggaggt
    19021 cgccgactcg ccgcgctcga cgatcgtcga gcaggtcgcc aacggtgtga cggtccggat
    19081 ggccgtcctc tacctgctgc tcggcggttc cgagcccgcg atcggaggcg ccgaatgagc
    19141 acctacgacc ttcacgaggg gactgtgacc accatcctca tcaggggagc ccggatcctg
    19201 ggcggcgccc cgagcgacat cctgctgcgc gacggcgtgg tggcggacat cggcgacctc
    19261 gcgggtgtca gggccgacca gacggtcgac gccgacgggc tgatcgccct gcccggcctg
    19321 gtggacctgc acacccacct gcgcgagccc ggccgggagg acgccgagac cgtggagacc
    19381 ggcacccagg ccgcggcgcg gggcgggtac accgccgtcc acgccatggc caacacctcc
    19441 ccggtggccg acaccgccgg cgtggtggaa caggtctggc ggctcggcca ggaatacggc
    19501 cactgcgacg tgcagcccgt gggcgccgtg acctccggcc tcgggggcag ccagctggcc
    19561 gagctcggcg cgatggccga ctccgcggcc cgcgtgcggg tcttctccga cgacggcaag
    19621 tgcgtgtccg acgccgtgct gatgcgccgg gctctggagt acgttaaggc gttcgacggc
    19681 gtcgtggccc agcacgccca ggagccccgg ctgaccgagg gcgcccagct caacgagggc
    19741 gaggtgtcgg ccaggctcgg cctgatcggc tggccggcgg tcgccgagga ggcgatcatc
    19801 gcgcgcgact gcctgctcgc cgcgcacgtc ggctcccggc tgcacgtctg ccacgtctcc
    19861 accgcgggct ccgtcgagat catccgctgg gccaagtcga agggctggga cgtgaccgcc
    19921 gaggtcaccc cgcaccacct gctgctgacc gactcctgcg cggagaggtc gccgctcggg
    19981 ccgtacaacc cgatctacaa ggtgaacccg ccgctgcgca ccgccgagga cgtgcgggcg
    20041 ctgcgcgagg cgctggccga cggcacgatc gactgcgtgg ccaccgacca cgcgccccac
    20101 ccggtcgagg acaaggagac cgagtgggcc gcggcggcca tggggatgat cggcctggag
    20161 accgccctgt ccgtggtcca ggaggccatg gtcgagaccg ggctgctcga ctgggccggc
    20221 gtcgccgacc gcatgtccgc gcggccggcc gcgatcggcc gcctggccgg gcacggccgc
    20281 cccgtcgagc ccggcgcccc cggcaacctc acgctgttcg acccgtcggt ccggcagccc
    20341 gtcgaccccg ccgcgatggc gtcgaagagc cgcaacaccc cctatgaggg gctgaccctg
    20401 cccggccgcg tcgtcgcgac gttcttgcgc ggccgtccca ccgttctcga agggaagctc
    20461 gtatgacagc cctgctcgtg cttgaggacg gacgcgtctt cgaggggacg ccgtacggcg
    20521 ccgtgggcga gacgttcggc gagatggtct tcaacaccgg catgaccggc taccaggaga
    20581 cgctcaccga cccctcctac caccgccaga tcgtcgcgat gaccgccccg cacatcggca
    20641 acaccggtgt caacgacgag gaccccgagt cccgcagggt ctgggtcgcg ggctacgtgg
    20701 tgcgcgagcc gtcccggatc ccgtcgaact ggcgctcccg caggacgctc gacgactacc
    20761 tgcgcgacca gggcgtggtc ggcatcgcga tgcccggcac ccgcgccctc acccgccatc
    20821 tgcgcgagcg cggcgcgatg cgcgcgggcg tcttcagcga gggcggcgag atcgccgacc
    20881 tggtcgagcg ggtgcggcgc tcgcccggca tggagggcgc cgacctggcc cgcgaggtca
    20941 gcacggcaga gccgtacgtc gtgccggcgg ccgggcgcaa gcgcttcacc gtcgccgcgg
    21001 tcgacctcgg catcaaggcc atgaccccgc agcggatgtc cgagcgggga tgcgaggtgc
    21061 acgtgctg
//
