LOCUS       NZ_BMMN01000002        22043 bp    DNA     linear   CON 22-DEC-2024
DEFINITION  Microbispora bryophytorum strain CGMCC 4.7138 sequence02, whole
            genome shotgun sequence.
ACCESSION   NZ_BMMN01000002
VERSION     NZ_BMMN01000002.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Microbispora bryophytorum
  ORGANISM  Microbispora bryophytorum
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Streptosporangiaceae; Microbispora.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 803079)
  AUTHORS   Sun,Q. and Zhou,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 202X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014645855.1-RS_2024_12_22
            Annotation Date                   :: 12/22/2024 07:39:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,203
            CDSs (total)                      :: 7,136
            Genes (coding)                    :: 7,048
            CDSs (with protein)               :: 7,048
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 16 of 88
            Pseudo Genes (incomplete)         :: 78 of 88
            Pseudo Genes (internal stop)      :: 7 of 88
            Pseudo Genes (multiple problems)  :: 11 of 88
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:18:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 636435
            Orig. end                         :: 658478
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMMN01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22043
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22043
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22043
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12043](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12043)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(141..158)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 17.36"
                     /tool="antismash"
     misc_feature    298..311
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.26"
                     /tool="antismash"
     misc_feature    complement(299..312)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.16"
                     /tool="antismash"
     gene            complement(493..753)
                     /locus_tag="IEY80_RS08525"
                     /old_locus_tag="GCM10011574_17400"
     CDS             complement(493..753)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY80_RS08525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10011574_17400"
                     /product="hypothetical protein"
                     /protein_id="WP_142569630.1"
                     /transl_table=11
                     /translation="MAKVREFFEDKKGSSSHPTVVDCGYQMVRTSEGVFLQLSTYGSDQ
                     RQTQKKTSQTLQFDREHAEQLLRLIISTFPDLRGTATGERP"
     misc_feature    complement(723..736)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.91"
                     /tool="antismash"
     misc_feature    1224..1239
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.07"
                     /tool="antismash"
     gene            1290..1973
                     /locus_tag="IEY80_RS08530"
                     /old_locus_tag="GCM10011574_17410"
     CDS             1290..1973
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017537440.1"
                     /locus_tag="IEY80_RS08530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_17410"
                     /product="hypothetical protein"
                     /protein_id="WP_142569632.1"
                     /transl_table=11
                     /translation="MARFVYVECLIRADMDALWEWTQRPELHQRWDLRFTEIDCLPRAD
                     DGPQWFRYAFKLLPGLVINGIGITTGDRHDTGGRTSALRFASDHPLSLIRSGSGYWRYV
                     PTDDGVRFITRYGYRPGWGRAVDLVFRPLIGWATAWSFDRLRLWLETGRTPERSLWQAL
                     AEICLRTLATAIAVTTTPAAVACLVGAAAILLPPLPSTPAARRCLRRPPDRQTVQPPHT
                     LMETR"
     misc_feature    1686..1688
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            1970..2644
                     /locus_tag="IEY80_RS08535"
                     /old_locus_tag="GCM10011574_17420"
     CDS             1970..2644
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017555661.1"
                     /locus_tag="IEY80_RS08535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_17420"
                     /product="DUF4166 domain-containing protein"
                     /protein_id="WP_142569633.1"
                     /transl_table=11
                     /translation="MTSIFQRALGADFARLHPQLQRRFGVSVVGGRACVGTGVMEHIWH
                     AGFTRPFLALGGTRNILVPAQGRQVPFTIENYPYVDTYGRETVSFVRTFDLPGRPRRFD
                     AQMVHDPAKGIIDYLGSHQHLAVDLDFQVDERGGLVIRSGGFRFHEGRLSCRLPALMTG
                     TAVVRESYDDEAGEFRIGVTVSHPRLGPMFGYWGAFQVHYVDVTEHGVPATVMPRREEA
                     RL"
     gene            complement(2647..4761)
                     /locus_tag="IEY80_RS08540"
                     /old_locus_tag="GCM10011574_17430"
     CDS             complement(2647..4761)
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0030245 - cellulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013504.5"
                     /locus_tag="IEY80_RS08540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_17430"
                     /product="glycoside hydrolase family 6 protein"
                     /protein_id="WP_142569635.1"
                     /sec_met_domain="Pkinase (E-value: 5.6e-39, bitscore:
                     129.6, seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 2.3e-06, bitscore: 23.2,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGGSEAGDLPGQHESGLRAGDPAQVGPYRLVRRLGEGGMGTVYL
                     GEAPDGTRVAVKLLHHTIAADPDFRRRFRREVEAAKRVARFCTAAVLDAEVDGETVYLV
                     TEYVPGPTLREAIERDGPLRGSSLDGLAVSIATALRAIHAAGIIHRDLKPGNVLLSPIG
                     PKVIDFGVAHLTDMAGHMSSAVVGTPSFMSPEQFDGGPLTPASDIFAWASTIAYAGTGH
                     APFGNGPLPVVLNRVVNGEPDLTGLDGPLGTLVARALAKNPAQRPAVQDILDTLTGSSA
                     PSVATLPGGGGRRRRSLVIGTGVGALALVAAVTATWLGTSSGPAASGSSATSSATSAAT
                     SAATVAAALPSASAADTGGNPLREPAVGFAYKQEPDPQRQADAWEAQGRKVDAALMRAL
                     AAVPHTVNLNGPATEAEDTVRSTMRLAAAHDAVPVFLTDYIPLTDCSDRGAPNEQEYRD
                     WIDQVAAGIGAGRAVVVLEPNSLTKVPGTDNCPTGGTAGTAERYRELGYAVDRLGALPH
                     TAVYLDGGIQGWPESVADIADRLVKAAIGRADGFYLNSSDFQDTDSLLLYGERLSRCVY
                     LVAAKGGSACADAEIDAVPADAPLTHFVIDTSRNGKGVWDAPEGKYADPQLWCNPPGRG
                     VGPRPTTDTDSELADAFLWIRDPGQSNGRCLRGGSGPEDPVHHQVDPVGGTWWPALALE
                     RARNAVPPLR"
     misc_feature    complement(4732..4734)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            4887..5522
                     /locus_tag="IEY80_RS08545"
                     /old_locus_tag="GCM10011574_17440"
     CDS             4887..5522
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019632027.1"
                     /locus_tag="IEY80_RS08545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_17440"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_142569637.1"
                     /transl_table=11
                     /translation="MGDTRTRLLEGALETLRTQGIAGASARAIATAAGVNQALVFYHFG
                     TVDDLLAAALRHGSEQRVAVYRARFAAVNTLKELLDLGRSLHADERAAGNLTVLAQMLA
                     GSQMDDKLAPATAAGLGMWVTEIEEVLGRVLAGSPLAEFVDVAGLARATAAAFVGLELY
                     EGVDKDGAEQAFDSLEQLAGLVAVLEDMGPIVRRTVRSRLRKAGSAET"
     gene            complement(5582..6529)
                     /locus_tag="IEY80_RS08550"
                     /old_locus_tag="GCM10011574_17450"
     CDS             complement(5582..6529)
                     /NRPS_PKS="Domain: PKS_ER (18-312). E-value: 1e-42. Score:
                     138.3. Matches aSDomain:
                     nrpspksdomains_IEY80_RS08550_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017569836.1"
                     /locus_tag="IEY80_RS08550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_17450"
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="WP_223853048.1"
                     /sec_met_domain="ADH_N (E-value: 7.4e-08, bitscore: 27.8,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 4.4e-14, bitscore:
                     48.1, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAVLFDRYGGPEVLYVGRVPRPEPAPGEVLVRVRAFSVNGGELA
                     ARAGDLRLLTGRKFPQRVGLDFTGEVAALGAGATGVAVGDRVWGVLGRTGFGSAADYVT
                     VRAERLGRVPDGLDLVEAAALPVATTAITALRDKAGVRPGERLLVRGAAGGVGNAAVQL
                     GKAYGAEVTALARAANLDFVRTLGAHHAIDHRSVSPAELGPFDVVLDTAGTDLRAFRRL
                     RSPGGRMVTIAFDQTRLAASLGYIAASAVHGRGRVRFFSGNPKRALFDDLAREVAEGRL
                     RPAVDTCFPLEETAAAHRALEAGGVRGKYVVRVD"
     aSDomain        complement(5594..6475)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEY80_RS08550_PKS_ER.1"
                     /evalue="1.00E-42"
                     /label="IEY80_RS08550_PKS_ER.1"
                     /locus_tag="IEY80_RS08550"
                     /protein_end="312"
                     /protein_start="18"
                     /score="138.3"
                     /tool="antismash"
                     /translation="RVPRPEPAPGEVLVRVRAFSVNGGELAARAGDLRLLTGRKFPQRV
                     GLDFTGEVAALGAGATGVAVGDRVWGVLGRTGFGSAADYVTVRAERLGRVPDGLDLVEA
                     AALPVATTAITALRDKAGVRPGERLLVRGAAGGVGNAAVQLGKAYGAEVTALARAANLD
                     FVRTLGAHHAIDHRSVSPAELGPFDVVLDTAGTDLRAFRRLRSPGGRMVTIAFDQTRLA
                     ASLGYIAASAVHGRGRVRFFSGNPKRALFDDLAREVAEGRLRPAVDTCFPLEETAAAHR
                     ALEAGGVRGKYVV"
     CDS_motif       complement(6041..6100)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEY80_RS08550_0002"
                     /evalue="3.90E-06"
                     /label="PKSI-ER_m5"
                     /locus_tag="IEY80_RS08550"
                     /protein_end="163"
                     /protein_start="143"
                     /score="19.4"
                     /tool="antismash"
                     /translation="GERLLVRGAAGGVGNAAVQL"
     CDS_motif       complement(6134..6175)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEY80_RS08550_0001"
                     /evalue="5.40E+01"
                     /label="PKSI-ER_m5"
                     /locus_tag="IEY80_RS08550"
                     /protein_end="132"
                     /protein_start="118"
                     /score="-3.0"
                     /tool="antismash"
                     /translation="LVEAAALPVATTAI"
     gene            6645..7325
                     /locus_tag="IEY80_RS08555"
                     /old_locus_tag="GCM10011574_17460"
     CDS             6645..7325
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017569835.1"
                     /locus_tag="IEY80_RS08555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_17460"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_229689549.1"
                     /transl_table=11
                     /translation="MVQESSRNAGPGLRADARRNLDRILVAARAVFAEHGIDAPMATVA
                     RRAGVGVATLYRRFPTRDALVRAAFAQQMKTCARALTEALADPDPWQGFQRLVETVCEL
                     QREEQGFPAAFVAAFPHSMMEHAQARGRVERDLMVLVRRAQAAGALRADFHPSDLAVAL
                     LAHCGLVTALPHDSAASRRLVAYLLQSFRAEAAHGALPPPSALSLRSFPIAADGSRRQR
                     PSRA"
     gene            complement(7523..7909)
                     /locus_tag="IEY80_RS08560"
                     /old_locus_tag="GCM10011574_17470"
     CDS             complement(7523..7909)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY80_RS08560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10011574_17470"
                     /product="hypothetical protein"
                     /protein_id="WP_142569641.1"
                     /transl_table=11
                     /translation="MLVEWLSAVAAAGGTAVVQAADTDMWVSVRQRVAHVLGHDDPGRE
                     RTELMRLDLTATDLASLAPGEAALIRARQEASWTARFEMLLESLGEAERERVACELNDI
                     ADQARHASVGGVPRNVFRGPSSTA"
     misc_feature    complement(7887..7902)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.79"
                     /tool="antismash"
     gene            complement(8225..9073)
                     /locus_tag="IEY80_RS08565"
                     /old_locus_tag="GCM10011574_17480"
     CDS             complement(8225..9073)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017569197.1"
                     /locus_tag="IEY80_RS08565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_17480"
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_142569643.1"
                     /transl_table=11
                     /translation="MIIITGATGQLGRGVVERLLTRLPADRIGVSVRDPLKAQDLVDLG
                     VRVRQGEFDDPASLAYAFEGASQVLIVSGPADARPHRTAIEAATAAGAERVLYTSHMGA
                     NPASPFVPMPSHAETEQDLAASGVAFTALRNGFYATTAVHFVRQALQSGTLVAPEDGPV
                     SWTAHADLAEVAAVALTEEGRLDGITPPLTGPESLDLADAAAIAADLTGREITRVTVPD
                     EEWVAGMVSHGTPEQQARFLLGMFEASRKGEFAEVGPALGELLGRQPATLRELLAATLT
                     N"
     misc_feature    complement(9059..9074)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.06"
                     /tool="antismash"
     misc_feature    complement(9061..9074)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.61"
                     /tool="antismash"
     misc_feature    9062..9075
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.61"
                     /tool="antismash"
     misc_feature    complement(9062..9077)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 20.67"
                     /tool="antismash"
     misc_feature    complement(9064..9077)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.61"
                     /tool="antismash"
     misc_feature    9065..9080
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.18"
                     /tool="antismash"
     misc_feature    complement(9067..9080)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.61"
                     /tool="antismash"
     gene            9158..9880
                     /locus_tag="IEY80_RS08570"
                     /old_locus_tag="GCM10011574_17490"
     CDS             9158..9880
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017619042.1"
                     /locus_tag="IEY80_RS08570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_17490"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_142569645.1"
                     /transl_table=11
                     /translation="MSDPENEAASGRDRTRAHIVSVAAGLLASGGRDALSTRAVAAAAG
                     TQAPTIYRLFGDKEGLLDAVAEYGFSSYLQDKKASPPADEPVEALRAGWELHVGFGLAN
                     PALFSLMYGAPTPGRQSPAAVAAFRMLGERIRAIAAAGRLKVGERLAADLVHAAGCGTV
                     FTLLALPEERRDPRLSEVARDAAIAAITTAAPVVETPGPAAAAMALRAALPDATALTDG
                     ERHVLGEWLDRLAADGSG"
     gene            complement(10001..12043)
                     /locus_tag="IEY80_RS08575"
                     /old_locus_tag="GCM10011574_17500"
     CDS             complement(10001..12043)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PT_HPP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.5"
                     /locus_tag="IEY80_RS08575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_17500"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_142569647.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 6.9e-51, bitscore:
                     168.5, seeds: 145, tool: rule-based-clusters)"
                     /sec_met_domain="PT_HPP (E-value: 1.9e-49, bitscore: 164.1,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="T1TS (E-value: 9.1e-42, bitscore: 139.4,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTEIVSRVFPALESDLERVREIVGLADVPSRADLTALTRQPAGH
                     RHLIRPTLALLSYYVLAGPERAAGVRAVKAAAAVELLHMASLQHDDVIDDARQRRGRPS
                     VNSVWGARLAVLAGDLLFVSGSRIVAELGEREALVSAEAVQRICSGMIAETADRFLLSR
                     TEEAYLEVTGAKTAELLSLACRLGAMQAGRDPEAEEAMARFGWHLGVAYQVRDDILDLT
                     ATPGELGKPTNSDLVEGVYTLPVIRALARDPALARLLRRGLPTAEAERARQLVLSCGAV
                     EDARKVAGEQAEAALLRLEGVGDPESREAVADYVRSVVGSVRQAGPAAVAVPAPAPASA
                     PSPASVQGDVLVRVVQERLDAWLLDSGLAATREESRHPRWSGMAAATALMWPGADAEQL
                     ETLARWMLVCVVLDDLFDEPGLADHAESARLRHRLALLIGGLDDTPPTGGAVATALAQA
                     WERIRLIQPPSWRTRAIGHLLDWLDAAEREACHRLSGYVPSLRDQFPLRLGSAGVPVFL
                     DAFEITCGREFEPSVRDHPLLRRLLDLGSATVLAENDLRTVDQDEATGSPYNLVRVLRH
                     ETGCTRQEAIDEVTRQVEDGYAQVDAILTSGPTILRPASGGVGSGGGGSLPVIGVLRVV
                     RDRLAGWRAIHDIDRYSSSATDSGTHLARLRRELLLEHAEARVAR"
     gene            complement(12064..12852)
                     /locus_tag="IEY80_RS08580"
                     /old_locus_tag="GCM10011574_17510"
     CDS             complement(12064..12852)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY80_RS08580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10011574_17510"
                     /product="ABC transporter permease"
                     /protein_id="WP_142569649.1"
                     /transl_table=11
                     /translation="MRGHWACYATAVRMTFVEHLRNRLALVIIVVFIPVWAILIYALSL
                     EVALPFHVRAAARVVALPANVLNQLAGALQILALITGFMMFVTTLNSASFDRRLVRSGF
                     PRLCLIAAKLTALVVVALCVAAYATGLICLTHRPAQPVLLATALFAGALIYGGIGIVLA
                     AVLTSDLAGLVLVTVICSVDLALQSPLATPAAAGALVRYLPDYGPMQGAVAAVALDTVP
                     WSAVAPAVCWAVGTALFGVSAFAGRTRVHRPVGGPATLSA"
     gene            complement(12849..13478)
                     /locus_tag="IEY80_RS08585"
                     /old_locus_tag="GCM10011574_17520"
     CDS             complement(12849..13478)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017601374.1"
                     /locus_tag="IEY80_RS08585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_17520"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_142569651.1"
                     /transl_table=11
                     /translation="MPSDEPVLRVRDVRKGYRGGPVLRAVNLDLPPGRVVGIVGENGAG
                     KTTLLRVLAGDLRPDGGSVRHRGHMGHCPQETVLHEAFTVEQHLRFFQVAYGLESLRRA
                     EELLDALRFSGSRRARPATLSGGTRQKLNLVLALMHDPDVLLLDEPYQGFDWETYVRFW
                     DLAEELRARGRSVLVVSHLAYDAARLDTLHRLEGGVLRVADRTGAA"
     gene            complement(13537..14187)
                     /locus_tag="IEY80_RS08590"
                     /old_locus_tag="GCM10011574_17530"
     CDS             complement(13537..14187)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY80_RS08590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10011574_17530"
                     /product="hypothetical protein"
                     /protein_id="WP_142569653.1"
                     /transl_table=11
                     /translation="MNVSRSRAYLAGGLAAAAAGVVALALTVVPSVAEGASGSAGARTR
                     PVADPSPKQQGGHTVLTCAMSTSAAQPITADPAVGKEARAVTAKGVLTLTGCVSPDKSF
                     PNLRSGTVTLQGSAQASCTGLQNVAGTGTVTWKDAQGQKLGTSTIRPNMDGIASYNPGD
                     MMLVGEVTQGKLKGKRIAGKAAPTSDIGQCSTKGVSSVQGSGTVAFIAVDAPK"
     misc_feature    14219..14232
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.06"
                     /tool="antismash"
     gene            14316..14555
                     /locus_tag="IEY80_RS08595"
                     /old_locus_tag="GCM10011574_17540"
     CDS             14316..14555
                     /GO_component="GO:0032993 - protein-DNA complex [Evidence
                     IEA]"
                     /GO_process="GO:0006276 - plasmid maintenance [Evidence
                     IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017592667.1"
                     /locus_tag="IEY80_RS08595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_17540"
                     /product="CopG family transcriptional regulator"
                     /protein_id="WP_142569655.1"
                     /transl_table=11
                     /translation="MSMKRTNVYADPEDLALIKEAAKRRGIPEAEIIREGIHLAAMANR
                     VWDEPLDWPTFVGGGEPVTNEEITSVVAKGAANR"
     gene            14552..14986
                     /locus_tag="IEY80_RS08600"
                     /old_locus_tag="GCM10011574_17550"
     CDS             14552..14986
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017592668.1"
                     /locus_tag="IEY80_RS08600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_17550"
                     /product="PIN domain-containing protein"
                     /protein_id="WP_142569657.1"
                     /transl_table=11
                     /translation="MIVIADTSGIIAASDRNAAESTECQSILREAGTVVISPLVLAEVD
                     HLAKVRFGSAARVQIIAFILSNARRLRFQVPEVSTEVLEAACAVRHRYASMDLDLADAV
                     NVVLAAEFRTDAMLTLDRRDFRAVRPLTPHKAFRLLPDDM"
     gene            complement(15139..15873)
                     /locus_tag="IEY80_RS08605"
                     /old_locus_tag="GCM10011574_17560"
     CDS             complement(15139..15873)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012792.5"
                     /locus_tag="IEY80_RS08605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_17560"
                     /product="N-acetyltransferase"
                     /protein_id="WP_142569659.1"
                     /transl_table=11
                     /translation="MTEERRRMPGPGGVPVFSYLEGVRDGRPWAYAIEDVGRGAADAIT
                     SRMPGWAVSAPVDLGQALLDRGARLLRHMHVMRCDLPLARPVTDTAPDGFLIVPCDRPP
                     AEILPAWFAAYPPGHPDHRPRDPEKALQEELVPLLGGEEIGPLLSCSVLAVRDGSPGTG
                     EVVGGVLVTGSNRGPWIADVFRHPDRSPRGLGALMLSVTLARAGAAGLDGMGLAVTEGN
                     PARHVYERLGFHVVETVMTVAI"
     gene            complement(15919..16158)
                     /locus_tag="IEY80_RS08610"
                     /old_locus_tag="GCM10011574_17570"
     CDS             complement(15919..16158)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010696297.1"
                     /locus_tag="IEY80_RS08610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_17570"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_142569661.1"
                     /transl_table=11
                     /translation="MPIVVEIDVLLAKRKMSVGELADRVGITPANLAVLKNGRAKAVRF
                     STLAALCEALECQPGDLLRWEDGDDADDGDDADA"
     gene            complement(16158..16655)
                     /locus_tag="IEY80_RS08615"
                     /old_locus_tag="GCM10011574_17580"
     CDS             complement(16158..16655)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022636.5"
                     /locus_tag="IEY80_RS08615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_17580"
                     /product="DUF2975 domain-containing protein"
                     /protein_id="WP_142569663.1"
                     /transl_table=11
                     /translation="MRQLTVLALRAVLVALLAGSVFVQAVMVPLLASDLERLDPDYAYL
                     RSPFLAITFLGVVTVEVVLVSVWRLVTMVRRGTVFSHDAFRWVNVVIGAFVAAALLIFA
                     LGVVLAPGEAVPPGVVLLVGGAGVAVLGVALIVLVLRMLLAQAVRRDIEAARMQAELDE
                     VI"
     gene            complement(16748..18208)
                     /locus_tag="IEY80_RS08620"
                     /old_locus_tag="GCM10011574_17590"
     CDS             complement(16748..18208)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138: FAD linked oxidase domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013714.5"
                     /locus_tag="IEY80_RS08620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_17590"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_142569665.1"
                     /transl_table=11
                     /translation="MIDRRSFLRVSALAGATALSGTAFAAAGPRPADWSALGRGLDGKL
                     IRPGDASYDNARRVFNSAFDSARPVGVAYCTTAADVSECLAFARRYGVPVTSRSGGHSY
                     AGWSTGSGLVVDVSPMSGVSSSGGHATVGAGARLVDVYAKLAAHGVSIPAGSCPTVGVA
                     GLTLGGGIGVVSRQYGLTCDALESLKVVTADGKVVTCSPSSHPDLYWASRGGGGGNFGV
                     ATSFTFRTHPTRSVTLFFLHWPWSKAAAVLKAWQAWAPAAPDAMWSNCHLDHDPSLDVM
                     VGGLYLGGRTACENLLQKLVDRVGSGPSTRYVATSAYDHAMMVEAGCASMSVAQCHRPG
                     TLPGQNARGKLVRDSFSAKSHFAYTPLSSAGIKALLARVAAPGRHTVMLDALGGAVARV
                     RPDATAFPHRKALFSVQYYSHFSGAAAWARAAHAAMRPYFGDHAYVNYIDPELKNWRQQ
                     YYGANAARLARVKAAYDPGRLFRLPQGV"
     misc_feature    18269..18284
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.68"
                     /tool="antismash"
     gene            complement(18347..20608)
                     /locus_tag="IEY80_RS08625"
                     /old_locus_tag="GCM10011574_17600"
     CDS             complement(18347..20608)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020547027.1"
                     /locus_tag="IEY80_RS08625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_17600"
                     /product="bifunctional polysaccharide
                     deacetylase/glycosyltransferase family 2 protein"
                     /protein_id="WP_142569667.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.3e-28,
                     bitscore: 94.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRQRRPAERRTAEPRGHWFLVAIAALLMAGALLLDAYAHNVVGE
                     TQPPPADFGDSAELEQIRSGGPLVNVSGSRPLSARPRPRRVALTFDDGPDPRWTPLLLD
                     LLREHRAKATFFVLGAHVAEHPELTRRMVAEGHEIGNHTYTHADLGAVPAWRARVEMSL
                     TQKALAAAAGIHTRLARIPYSSGPGAAGYRQLATMRLLGDEGYLVTFTDVDTQDWSRPP
                     VNEMVLASLARTVEGEGAVIMFHDSGGDRARTLAAVDRLLTRLEKKGYAATTLTDAVGL
                     PTAHTAASADERVLGAILGFAQRASFAFVEALGWFLAAAGVLTLLRLALFVALAWAHAR
                     RTRGRSANAVVPHGTAAPPVSVIVPAYNEAAGIEATVRSLVATDYPGPVEVVVVDDGSA
                     DETGAIAASLGLPGVRVIRQPNAGKPVALTTGIAHSAHGILVMVDGDTVFEPPTIGHLV
                     RPLADGTVGAVSGNTKVGNRRGMIGRWQHIEYVVGFNLDRRAFDLLGCMATVPGAIGAF
                     RREAIASAGGVSADTLAEDTDLTMAISRGGWRVVYEERARAWTEAPASLGQLWRQRYRW
                     CYGTLQAIWKHRGAVAERRPFGRRCLGYLTLFQVILPLLAPVVDVMALYGLFVGDPLPV
                     VAVWAGFVAVQALTGWYALRLDGERASVLWVLPLQQFVYRQLMYLVVIQSVATAVLGAR
                     LRWHTVRREGTFTLAGPSTPRLSAPRPPVPRSPASRSSAGRRRRAVTDGNAPRRRRSRP
                     "
     gene            complement(20616..21185)
                     /locus_tag="IEY80_RS08630"
     CDS             complement(20616..21185)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY80_RS08630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_142569669.1"
                     /transl_table=11
                     /translation="MEDRRPERAAVFVDQSGRRAKILTAAAVGGAIVVLALTLTLVSGA
                     LAGPELPPMRWPGTQVQPVVERSPAGSTTPSRGSERRRAPRDEAAANGTPRATAPPARR
                     TPSARRLPSRAPSPSARKSPRPSRTPSASSLPEPDVEISAPGEPTPAPQVSEVVQSTAP
                     AEEATRPPASEPGTVQTPPQQPGAAQ"
     misc_feature    21206..21221
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.0"
                     /tool="antismash"
     misc_feature    21233..21242
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.63"
                     /tool="antismash"
     misc_feature    complement(21354..21366)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 20.45"
                     /tool="antismash"
     misc_feature    complement(21435..21451)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.06"
                     /tool="antismash"
ORIGIN
        1 cctgccccgg cactttagcg accgcctcgc tgatgcacaa cccgaactaa tgctacctct
       61 tgtcaatagc cgcgcgaaag taggccttat ggggatgaat cgcccgctcg taagtgctgc
      121 ataggcggca acttctcttg ataacagaga ggtaacgtcg caactgtcgt agtagtgcga
      181 ccggccgggg gctcaaccgg ctcaggcatc gcgggtggaa ggactgcctc cgccgtgcgg
      241 tgcggtagcg gtcaaactgc ggggtgcgga agacggtggg cgctgtctac tcagcggagc
      301 acgctgagtg actgtcatca gccgttgaat gacatgagcc atgtccccta cgggtggaga
      361 cagtgctgcc tcgcaggggc gaaatctatc gggcggccga ggagcaggtc ggcgctacta
      421 ctgcgtcact cattacgtga acgagttgtg cttggcaggc tgtacgcagc gcctggacgg
      481 ccaggtcgca ggttaggggc gctctcccgt cgccgttcct cgaaggtcgg ggaaggtgga
      541 aatgatcagg cggaggagct gctcagcatg ttcgcgatcg aactggaggg tctggctggt
      601 cttcttctga gtctgccgct ggtccgaccc ataggtgctg agctgcaaga atacgccctc
      661 gcttgtgcga accatctgat aaccgcagtc cacgaccgtg gggtgcgagc tagagccctt
      721 cttgtcctcg aaaaattccc tgaccttcgc catgccggca ttctggcgaa cacttcggtg
      781 ctagggaagg ggggaagccg tggatgcatt cgtgacctgt ggttgtccgc agagataatc
      841 gtctcgcttg gccagcggtc gagctgacct acgccgtcag ccggaactcc tcgtggcgct
      901 cctcaagcgc acgtgcatca agccagtccc gccgtgacct gggcaagctc aagctgagcc
      961 cgttcatctc ctgcaggtca tagcgcaaca tgagaccatc gatctcttcc ggtgcgtccg
     1021 cctgaacctc gacgatgtga tcaggccgtc tgtcgaggac agaaccaaac aggtgcggcc
     1081 atgtcaggag cagcctccct gagcggcgcg gccaccctga tgcagtcatc cgtcagtcgg
     1141 gagtgcatgc gtgagatgcc ggcatcgcca tcgctcggaa agtcaggggt gaacgaccag
     1201 tgctgatgcc ctgaccagga agcttgagcg tctgctcaaa tcggcctacg ctcaagtttg
     1261 agcgaacgct caatggctgg agggtgtgca tggctcggtt tgtgtacgtg gagtgcctga
     1321 tcagggctga catggacgcc ctctgggagt ggacgcaacg gcctgagctg catcaacggt
     1381 gggatctgcg gttcacggag atcgactgcc tgccgcgtgc cgacgacggg ccgcagtggt
     1441 tccggtacgc cttcaagctc ctgcccgggc ttgtcatcaa cggcatcggc atcacgacgg
     1501 gggaccggca cgacaccggc ggcaggacgt cggcgttgcg gttcgcctcg gaccatccgc
     1561 tctcgctgat ccgctccggc tccggctact ggcggtacgt ccccaccgac gacggcgtgc
     1621 gcttcatcac tcggtacggc tatcgccccg gctggggcag ggccgtcgac ctcgtgttcc
     1681 ggccgttaat cggctgggcg acggcctggt ccttcgaccg gctccgcctc tggctggaaa
     1741 ctggccgtac gccggagcgt tccctgtggc aggccctcgc cgaaatctgc ctgcgcaccc
     1801 tcgcgaccgc catcgccgtc acaaccactc cggccgccgt cgcctgcctc gtgggagcgg
     1861 cggccattct cctgccgccg ctgccgtcga ccccggcggc ccgccgctgc ctgcgccgtc
     1921 cgcccgaccg gcagacggtg caacccccgc acaccctgat ggagacccga tgacgtcgat
     1981 cttccaacgt gccctcggcg cggacttcgc ccgcctgcac ccgcaactcc aaagacgctt
     2041 cggcgtcagc gtcgtcggcg ggcgggcctg cgtcggcacg ggggtcatgg agcacatttg
     2101 gcacgcggga ttcacccggc cgttcctcgc cctcggcgga acccgcaaca tcctggtccc
     2161 cgcgcagggc cggcaggtgc cgttcaccat cgaaaactac ccgtacgtcg acacgtacgg
     2221 ccgggagacg gtcagcttcg tccgcacctt cgacctgccc ggccgccccc ggcggttcga
     2281 cgcacagatg gtgcacgacc ctgccaaagg catcatcgac tacctgggct cgcaccagca
     2341 cctggccgtt gacctggatt tccaggtgga cgagcgtggg ggcctggtca tccggtccgg
     2401 cgggttccgc ttccacgagg gccggctctc ctgccgtctc cccgcactca tgaccggcac
     2461 cgccgtggtc cgggagtcgt acgacgacga ggcgggggag ttccgcatcg gggtgacggt
     2521 ctcccacccc aggctgggcc ccatgttcgg ctactggggc gccttccagg tccactacgt
     2581 cgacgtcacc gagcacggcg tgcccgctac ggtgatgccg cggcgcgaag aggcacgcct
     2641 gtgagctcaa cgcagcgggg gcacggcgtt gcgagcgcgt tcgagggcga gggcgggcca
     2701 ccaggtgccg ccaacggggt ccacctggtg atgcaccgga tcctccggcc cggagccgcc
     2761 gcggaggcac cgcccgttgg actggccggg atcgcggatc cacaggaagg cgtcggccag
     2821 ctcgctgtcg gtgtcggtgg tcgggcgggg gccgacgccc cgccctggcg ggttgcacca
     2881 caactggggg tcggcgtact tgccctcggg ggcatcccac acgcccttgc cgttgcggct
     2941 ggtgtcgatg acgaagtggg tcagtggcgc gtcggccggc acggcgtcga tctcggcgtc
     3001 cgcacacgcg cttccgccct tggcggcgac gaggtagacg cagcgggaga gcctttcccc
     3061 atataggagg aggctgtcgg tgtcctggaa gtccgagctg ttcagataga agccatcagc
     3121 ccgccctatc gcggccttga ccagccgatc ggcgatatcg gcgacggact cgggccaacc
     3181 ctggatgccg ccgtcgaggt agacggccgt gtgcggcagc gcccccaggc ggtcgacggc
     3241 gtagccgagc tcgcggtagc gctcggcggt ccccgcggtg ccgcctgtcg ggcagttgtc
     3301 ggtgccgggc actttggtca ggctgttcgg ttcgagcacg accaccgccc ggcccgcgcc
     3361 gatgccggcc gcgacctggt cgatccagtc gcggtactcc tgctcgttcg gcgccccgcg
     3421 atcggagcag tccgtcaacg ggatgtaatc cgtgaggaac accggcacgg cgtcgtgggc
     3481 cgcggcgagc cgcatcgtgg acctgacggt gtcctcggcc tcggtggccg gtccgttcag
     3541 gttcaccgtg tgtggcaccg cggcgagggc gcgcatcagc gcggcgtcga ccttcctgcc
     3601 ctgcgcctcc caggcgtccg cctggcgctg cgggtcgggc tcctgcttgt acgcgaaccc
     3661 tacggcgggc tcccgcagcg gattgccgcc ggtgtcggcg gcggaagcgg acgggagcgc
     3721 ggcggccacg gtggcagccg acgtggcagc cgaggtggcg gatgaggtgg cggacgagcc
     3781 ggatgcggcg gggcccgacg aggtgccgag ccaggtggcg gtcaccgccg cgaccagggc
     3841 aagcgcgccc accccggtcc caatcaccag gctgcggcgg cgtctcccgc cacccccggg
     3901 aagagtggcg accgaaggtg ccgaagaacc ggtgagcgtg tcgaggatgt cctgaacggc
     3961 cggtcgttgt gccgggtttt tggccagggc gcgtgccacc agcgtgccca gcggtccgtc
     4021 gaggccggtc aggtcgggtt ccccgttgac gactcggttg agcacgacgg ggagcggtcc
     4081 gttgccgaag ggggcgtggc ctgtgccggc gtacgcgatc gtgctcgccc aggcgaagat
     4141 gtcggaggcg ggtgtgagag ggccgccgtc gaactgttct ggggacatga acgagggtgt
     4201 cccgacgacc gcgctgctca tgtgtccggc catgtcggtc aggtgggcga caccgaagtc
     4261 gatgaccttg gggccgatgg gggagagcag gacgttgccg ggtttgaggt cgcggtggat
     4321 gatgccggcg gcgtggatgg cgcgtagggc ggtcgcgatg ctgacggcga gcccgtccag
     4381 gcttgagccg cgtagcggtc cgtcccgttc gatggcctcc cgcagggtcg gccctgggac
     4441 gtactcggtg accagataga cggtttctcc gtccacctcg gcatcgagga cggcggcggt
     4501 gcagaagcgg gcgactcgct tggccgcttc cacctcgcgg cggaaccggc ggcgaaagtc
     4561 ggggtcggcg gcgatcgtgt ggtggagcag cttgaccgcc acgcgtgtgc cgtccggtgc
     4621 ctcgcccagg tagacggtgc ccatcccgcc ctcgcccagc ctgcgcacca gccggtaagg
     4681 ccccacctgg gccgggtcac cggcgcgcag gccggactca tgctgcccag gtaagtcccc
     4741 cgcctcgctg ccgccgttca caacgccccc gctgggatgt ccggaaggtc aggtcactac
     4801 ggatcctatt gaccgccgcc gggcgcggcc atggccgaac acgtgccgct acggtgaagc
     4861 cgcgaagagg aacgaagggg gagacgatgg gcgacacccg gacgaggctg ctcgaagggg
     4921 ctctggagac gttgcggacc cagggcatcg cgggggcctc ggcgcgggcg atcgccaccg
     4981 ccgccggggt caaccaggcg ctcgtcttct accacttcgg cactgtcgac gacctcctcg
     5041 ccgcggccct gcggcacggg tcggagcagc gggtggccgt ctaccgggcc cgattcgcgg
     5101 ccgtgaacac cctgaaggaa ctactcgacc tcggccgttc cctgcacgcc gacgagcgcg
     5161 ccgcgggaaa cctgaccgtg ctcgcccaga tgctcgcggg cagccagatg gacgacaaac
     5221 tcgcccccgc caccgctgcc ggcctcggca tgtgggtcac cgagatcgag gaggtcctcg
     5281 gccgcgtgct ggccggcagc ccgctcgcgg agttcgtgga cgtcgccggg ctcgcccgcg
     5341 ccaccgccgc cgccttcgtc ggcctcgaac tgtacgaggg cgtcgacaag gacggcgcgg
     5401 agcaggcgtt cgacagcctg gagcagctcg ccggcctggt cgccgtcctg gaggacatgg
     5461 gcccgatcgt ccggcgcacc gtacgctccc ggctccgcaa ggccggctcc gctgagacgt
     5521 aagccgagaa gtgagccgag aagcgagtcg gcgcagcgcc accccctcgg ccggaccgca
     5581 ctcagtcgac cctgaccacg tacttgcccc gcaccccgcc cgcctccaac gcgcggtgcg
     5641 ccgccgctgt ctcctccagc gggaagcacg tgtccaccgc agggcgcagt ctcccctccg
     5701 ccacctcacg ggcgaggtcg tcgaagagcg cccgtttggg gttgccgctg aagaagcgca
     5761 cccggccgcg gccgtgtacg gcgctggcgg cgatgtagcc gagtgaggcg gcgagcctgg
     5821 tctggtcgaa ggcgatggtg accatgcggc cgccgggcga ccgcaggcgc cggaaggccc
     5881 gcaggtcggt gcccgcggtg tcgaggacca cgtcgaacgg gcccagttcc gccggcgaga
     5941 cgctccggtg gtcgatggcg tggtgggcgc cgagcgttcg gacgaagtcg aggttggcgg
     6001 cgcgggccag ggccgtgacc tcggccccgt aggcctttcc gagttggacg gcggcgttgc
     6061 cgacgccgcc cgcggcgccg cgtacgagca gtcgctcgcc ggggcgcact ccggccttgt
     6121 cacgcagcgc cgtgatggcc gtggtcgcca ccggcagtgc ggcggcctcc acgagatcca
     6181 gcccgtccgg gacccggccg agccgctcgg cccggacggt cacatagtcg gcggcgctgc
     6241 cgaatccggt gcggccgagg acgccccaca cccggtcgcc gaccgcgaca cccgtcgcgc
     6301 cggcgccgag cgcggcgacc tcgccggtga agtccaaccc gacgcgttgc gggaacttcc
     6361 gtccggtgag gaggcggagg tcgccggcac gggccgccag ttcgccgccg ttgacgctga
     6421 acgcgcgcac ccgcacgagc acctcgccgg gcgccggttc agggcgtggc acccggccca
     6481 cgtacagcac ctcggggccg ccgtagcggt cgaaaagcac tgctctcatc gtgcgatcgt
     6541 ccatcgttct caccttcgcc atcagtggcc gtacggggaa tccggccccg agcgtaggct
     6601 cctaactgga cgcgatcgtc cgcttaggta ggaagtgaga gacagtggtg caggaatcct
     6661 ctcggaacgc gggcccgggg ctgcgggccg acgcccggcg caacctggac cgcatcctcg
     6721 tcgccgcccg tgcggtcttc gccgagcacg ggatcgacgc gcccatggcg accgtggccc
     6781 gccgggcggg ggtcggtgtg gcgacgctgt atcggcgttt tccgacccgg gacgccctgg
     6841 tgcgggccgc gttcgcgcag cagatgaaga cctgcgctcg ggcgcttacc gaggcgctgg
     6901 ccgacccgga cccctggcag ggcttccagc ggctggtcga gacggtctgc gagcttcagc
     6961 gggaggagca gggtttcccc gccgcgttcg tcgcggcctt cccgcacagc atgatggaac
     7021 acgcgcaggc ccgagggcgg gtcgagcggg acctcatggt cctggtccgc agagcccagg
     7081 cggcgggcgc gctgcgggcc gatttccacc cttccgacct cgccgtggcc ctgttggccc
     7141 actgtggtct ggtcaccgcg ctgccgcatg acagtgccgc gtcccggcgc ctggtggcgt
     7201 atctgctcca gtcgttccgc gccgaggcgg ctcacggggc cctgcctccg ccgagtgctc
     7261 tgtcgttgcg cagtttcccg atagcggccg acggctcccg gagacaacgc ccctccaggg
     7321 cctgatccga gagtgggcga ctcccggcag ccgggtccta ctgatccggg tcccaggcct
     7381 ggagcaggtc gaacagacgc gggtcgccgt cgaccttcag ggagtccacc gccgatggtc
     7441 gatgagcttc gatctgggcg gtcaggtcat ccggcgtcag gtcatcggcg gtcaggtcat
     7501 tggcggtcag gtcatcggct ggtcaggccg tcgagctcgg tccacggaag acgttcctcg
     7561 gcacgccccc cactgatgcg tggcgcgcct ggtcggcgat gtcgttcagt tcgcaggcga
     7621 cccgttcgcg ttcggcctcg ccgagactct ccagcagcat ctcgaatcgg gccgtccagg
     7681 acgcctcctg ccgggcccgt atcagtgccg cctcccccgg ggcgagcgag gcgagatctg
     7741 tcgcggtcag atccagccgc atcaattccg tccgctcacg tccgggatcg tcatggccga
     7801 gcacatgcgc cacccgctgc cgcacgctta cccacatgtc cgtgtccgcg gcctgcacca
     7861 ccgcggttcc gccggccgcg gccaccgctg acagccattc gaccagcatt ttcggcctcc
     7921 tcacgcgttt tcatcacact ttatatctgg ctgtgatgag gtcgccggat gttccgaaag
     7981 ggaaatcggc ccgggaaacg aggccgcctg aagggatttt ctcctcataa tgccgcggat
     8041 cgccggcagc gggggctcgg ctcttaccgc acgcggagac acgcggagac acgcagagaa
     8101 tgacgcagcg agcggacacg atgcggacac gatgcggaga cggtgtggag acggtgcgga
     8161 aacggtcacg tcgtagatgg accagtcgcg aaatcaggcg tagaagggcc ggacgccgca
     8221 cagctcagtt cgtcagcgtg gccgccagca gctcgcgcaa cgtggccggc tgacgaccga
     8281 gcagctcccc gagggcgggg ccgacctcgg cgaactcccc cttacggctc gcctcgaaca
     8341 tgcccagcaa gaaccgggcc tgctgctcgg gcgtgccgtg cgacaccatg ccggcgaccc
     8401 actcctcgtc cgggacggtg acgcgggtga tctcgcgtcc cgtcaggtcg gcggcgatcg
     8461 cggcggcgtc cgcgaggtcg agcgactcgg gaccggtcag cggcggggtg atcccgtcga
     8521 gccggccctc ctccgtcagc gcgacggcgg ccacctcggc gaggtcggcg tgggccgtcc
     8581 aggagaccgg gccgtcctcg ggggcgacga gcgtgccgct ctgcaatgcc tgacgcacga
     8641 aatggaccgc ggtggtcgcg tagaagccgt tgcgcagcgc ggtgaacgcg accccggatg
     8701 ccgccaggtc ctgctccgtc tcggcatggg acggcatcgg gacgaagggg gaggccgggt
     8761 tcgcccccat gtggctggtg tagaggaccc gctcggcccc cgcggcggtg gcggcctcga
     8821 tcgccgtacg gtgcgggcgg gcgtccgccg ggcccgagac gatcaacacc tgcgacgcgc
     8881 cctcgaacgc gtacgccagg ctcgcgggat cgtcgaactc gccctgacgg acccgtacgc
     8941 cgaggtccac gaggtcctgg gccttgaggg ggtcgcggac gctgacgccg atccggtcgg
     9001 cgggcagacg ggtgagcagg cgctcgacga cgcctcggcc gagctgaccg gtcgctccgg
     9061 tgatgatgat catgattcac tccttgctat cgctgatatc ggttaaacgc taacactgga
     9121 aaatcgacga tagcaacacg ctgatatcgt tggaagcatg agcgatccgg aaaacgaggc
     9181 ggcgagcggc cgggacagga cgcgggcgca catcgtgtcg gtcgcggccg ggctgctcgc
     9241 gagcggcggg cgcgacgccc tctcgaccag agcggtggcc gccgcggcgg gaacccaggc
     9301 gccgacgatc taccggttgt tcggcgacaa ggagggcctg ctcgacgcgg tcgccgagta
     9361 tggcttcagc tcatatctgc aggacaagaa ggcgagcccg ccggccgacg agccggtcga
     9421 ggcgctgcgg gccggatggg agctgcacgt cggcttcggg ctggcgaacc ccgccctgtt
     9481 ctcgctcatg tacggcgctc ccacgccggg acggcagtcg cccgccgccg tcgccgcctt
     9541 ccgcatgctg ggggagcgca tccgcgccat cgccgccgcg ggccggttga aggtgggcga
     9601 gcgcctggcg gcggacctcg tgcacgccgc gggctgcggc acggtcttca cgctgctcgc
     9661 cctgcccgag gaacggcgtg acccgcgcct ttccgaggtg gcccgcgacg cggcgatagc
     9721 cgccatcacc accgccgctc ctgtggtcga aacccccgga cccgccgcgg cggcgatggc
     9781 gctgcgcgcc gcgctcccgg acgccaccgc tctcaccgac ggagaacggc acgtgctcgg
     9841 cgaatggctc gaccgcctcg ccgcggacgg atccggctga ggtcccggca ccccgctgag
     9901 aagaacgggc tgagaagaac gggccgggga gaacgggctg agaagaacgg gccgaaatga
     9961 gcggcccggg accagcgggc cgatatgaag cgggccggga tcagcgcgcc acgcgggcct
    10021 cggcgtgttc gagcaggagt tcccggcgca gccgggccag gtgcgtcccg ctgtcggtgg
    10081 ccgacgagct gtagcggtcg atgtcgtgga tggcgcgcca gcccgcaagc cgatccctga
    10141 cgactcgcag gactccgatg accggcagcg agcccccacc acccgagccc acgccacccg
    10201 aggcgggccg caggatggtc ggcccggacg tgaggatggc gtccacctgg gcgtagccgt
    10261 cctcgacctg gcgggtcacc tcgtcgatcg cctcctgcct ggtgcagcct gtctcgtggc
    10321 ggagcaccct gacgaggttg tagggactgc cggtggcttc gtcctggtcc acggtccgca
    10381 ggtcgttctc cgcgagcacg gtggccgagc cgaggtccag caaccgccgc agaagcgggt
    10441 gatcgcgtac ggacggctcg aactcccggc cacacgtgat ctcgaaggcg tccaggaaga
    10501 cgggcacccc tgcgctcccc aggcgcagcg ggaactggtc gcgcaggctg gggacgtagc
    10561 cgctgagccg gtggcatgcc tcgcgctcgg ccgcgtccag ccagtcgagc aggtggccga
    10621 tggcccgcgt ccgccatgac ggcggctgga tcaggcggat ccgctcccac gcctgggcca
    10681 gggccgtggc gaccgcgcca ccggtcggcg gggtgtcgtc gagcccgccg atgaggaggg
    10741 cgagccggtg acgcagccgg gcggactccg cgtggtcggc gagacccggc tcgtcgaaga
    10801 ggtcgtcgag cacgacgcac accagcatcc accgggccag ggtttcgagc tgctcggcgt
    10861 cggcgcccgg ccacatcagc gcggtggccg cggccatgcc gctccagcgc gggtgacggc
    10921 tctcctcccg cgtggcggcc agcccggagt ccagcaacca ggcgtccaac cgctcctgca
    10981 ccacccggac caggacgtcg ccctgaacgg aagcggggga aggggccgaa gcgggcgcgg
    11041 gcgcgggcac ggcgacggca gccgggccgg cctgtctcac ggagcccacg accgaccgca
    11101 cgtagtcggc caccgcctct cgcgactccg gatcgccgac gccctccagc cgcagaaggg
    11161 ccgcctccgc ctgctcgccg gcgaccttcc gggcgtcctc cacggctccg caggacagga
    11221 ccagttgccg tgcgcgctcg gcctcggccg tcggcagacc gcgacgcagc agccgggcga
    11281 gcgcggggtc gcgggccagg gccctgatca cggggagtgt gtagacgcct tcgacgaggt
    11341 cggagttggt gggtttcccc agctctccgg gagtggcggt caggtccagg atgtcgtcgc
    11401 gcacctggta ggccacgccg agatgccagc cgaaccgcgc catggcctcc tccgcctccg
    11461 ggtcccgccc ggcctgcatg gcgcccagcc ggcaggcgag ggacagcaac tcggccgtct
    11521 tggcgccggt cacctccaga taggcctcct cggtgcggga gagcaggaag cggtcggcgg
    11581 tctcggcgat catccccgag cagatgcgct ggacggcctc ggcggacacc agtgcctcgc
    11641 gctcgcccag ctcggcgacg atccggctgc cgctgacgaa caggaggtca ccggccagga
    11701 ccgccaggcg tgcgccccac acgctgttga cgctcggcct gcccctgcgc tgccgcgcgt
    11761 cgtcgatgac gtcgtcgtgc tgcagcgacg ccatgtgcag cagctcgacg gccgccgcgg
    11821 ccttgacggc acggacgccg gcggcccgct ccgggccggc gagcacgtag tacgacagca
    11881 gggccaaggt tggccggatc aggtggcggt gaccggccgg ctgcctggtc agcgccgtca
    11941 gatcggcgcg gctcggcacg tccgccaggc cgacgatctc gcgcacccgt tccaggtcgg
    12001 actccagggc gggaaagaca cgggaaacga tctcagttgt catggatgct cctgacgggg
    12061 gattcaggcg gaaagcgtgg ccggcccgcc caccggccgg tgtacgcgcg tgcggccggc
    12121 gaaagcggag acaccgaaga gcgccgtgcc cacggcccag cacacggcgg gggcgacggc
    12181 gctccagggc accgtgtcca gggccaccgc cgcgaccgcc ccctgcatcg gcccgtaatc
    12241 gggcaggtaa cgcaccaggg cgccggccgc ggccggagtg gcgagggggc tctgcagggc
    12301 cagatcgacc gagcagatca cggtgacgag gaccaggccg gccaggtcgc tggtcagcac
    12361 ggcggccagc acgatgccga tcccgccgta gatcagcgcc ccggcgaaga gggcggtggc
    12421 gagcagcacg ggctgcgccg gccgatgggt caggcagatc agaccggtcg cgtacgccgc
    12481 gacgcagagc gcgaccacca ccagggcggt gagcttcgcc gcgatcaggc acagccgggg
    12541 aaagcccgac cgcaccagcc ggcgatcgaa ggacgccgag ttcaacgtgg tcacgaacat
    12601 catgaacccg gtgatcaacg cgaggatctg cagcgccccg gcgagctggt tgagcacgtt
    12661 ggccggcagg gcgacgaccc gcgccgcggc gcgtacgtgg aacgggagcg cgacctccag
    12721 ggacagggcg tagatgagga tcgcccacac cgggatgaag accacaatga tcacgagagc
    12781 cagccggttg cgcagatgct ccacgaacgt catgcgcacg gcggtggcgt agcaggccca
    12841 gtgacctctc acgcggcacc ggtcctgtcc gcgacccgca gcacgccgcc ctccagccga
    12901 tggagcgtgt cgaggcgcgc ggcgtcgtac gcgaggtggg agacgaccag caccgagcgg
    12961 ccacgcgcgc gcagttcctc ggccaggtcc cagaaccgga cgtacgtctc ccagtcgaag
    13021 ccctggtagg gctcgtcgag caggagcacg tccggatcgt gcatcagggc caggacgagg
    13081 ttgagcttct gccgcgtgcc gccgctcagc gtggcggggc gggcccggcg ggagccggag
    13141 aaccgcagcg cgtcgagcag ttcctcggcc cggcgcagac tctccaggcc gtaggcgacc
    13201 tggaagaacc gcaggtgctg ctcgaccgtg aacgcctcgt gcagcaccgt ctcctgcggg
    13261 cagtgaccca tgtgcccgcg gtggcgcacc gacccgccgt ccggccgcag gtcgcccgcg
    13321 aggacgcgca gcagcgtggt cttgcccgcg ccgttctccc cgacgatccc caccacccgg
    13381 ccgggcggca gatcgagatt caccgcacgc aggaccgggc caccccggta gcccttccgt
    13441 acgtcccgca cccgcagcac gggctcatcc gacggcatgc gccacctcct ccgacccggt
    13501 cccgcctgac tgcgctacct gtgtgctacc tgtgtgctac ttgggtgcgt cgacggcgat
    13561 gaacgcgacg gtgccgctgc cctggacgct gctcacgccc ttggtggagc actggccgat
    13621 gtccgaggtg ggggcggcct tcccggcgat ccgcttgccc ttcagcttcc cttgggtgac
    13681 ctcgccgacc agcatcatgt cgcccgggtt gtacgaggcg attccgtcca tgttgggccg
    13741 gatcgtggag gtgcccagtt tctggccctg ggcgtccttc caggtgacgg tgcctgtgcc
    13801 ggcgacgttc tggaggccgg tgcaggacgc ctgcgcgctg ccctggaggg tgaccgtccc
    13861 cgagcggagg ttggggaagc tcttgtcggg agagacgcag ccggtgagcg tcaggacgcc
    13921 cttggcggtc accgcgcggg cctccttgcc caccgcgggg tcggcggtga tcggctgggc
    13981 ggcgctcgtg ctcatcgcgc acgtcagcac ggtgtggccg ccctgctgct tcggcgaggg
    14041 gtcggcgacc ggcctggtgc gcgcgccggc gctgcccgac gcgccctcgg cgaccgacgg
    14101 gacgaccgtc agggccaggg ccaccacacc cgccgcggcg gcggcgagac cgccggccag
    14161 gtacgcgcga gatcgagata cgttcatgga cttccccccg aatgattgct gtcggcaatc
    14221 tacttatcac aatcggtaac gggagggccg gtgagtcgag acgggtcacc cgccgtaccc
    14281 cctggtcgac ccggtacgtg tgttagcgtt ggtacatgtc tatgaagagg acgaacgtct
    14341 acgccgatcc tgaggacctt gccctcatca aggaggcggc gaagcgcagg ggcattccgg
    14401 aggcggagat catccgtgag ggaatccact tggctgcaat ggcgaaccgt gtgtgggacg
    14461 agccgttgga ctggccgacc ttcgtaggcg gcggcgagcc ggtcaccaac gaagagataa
    14521 cctcggtggt ggccaaggga gctgccaaca ggtgatcgtc atcgcggaca cctccggcat
    14581 catcgccgcc tctgatagga atgcggccga gagtaccgag tgtcagagca ttctccgtga
    14641 ggccgggacc gtagtcatct ctccgttggt tttggcggaa gtcgatcacc tggccaaggt
    14701 ccgtttcggc tctgccgctc gggtgcagat catcgccttc atcctctcca atgcgcggcg
    14761 tctgcgcttt caggtcccgg aagtctcgac cgaagtcctg gaggcggcat gtgcggtgcg
    14821 gcaccgctat gcatcaatgg acctggacct cgccgacgcg gtcaatgtcg tgctggccgc
    14881 ggagttccgg acggacgcca tgctcacgct ggaccggcgt gatttccggg cggtgcgccc
    14941 tctgacaccg cacaaggcat tccggctgtt gccggacgac atgtagccga gcctcagact
    15001 tcccgcgaag gggcccgtgg gtcgtcggtt acatttcctg gggctcccga tcagggcgcc
    15061 gtctgggagg cggaagccga agccggcctc cgccctcgcg gtcacggcga tgaaagtgtg
    15121 gcgacccggc ggttcggctc agatcgctac cgtcatcacg gtctcgacga cgtggaaacc
    15181 gagcctctcg tacacgtggc gggcggggtt gccttcggtg accgccaggc ccatgccgtc
    15241 cagcccggcc gcgccggccc gggccagggt gaccgacagc atgagcgcgc cgagacctcg
    15301 cggcgaccgg tccggatgcc ggaacacgtc cgcgatccac ggtccccggt tcgagccggt
    15361 gacgagaact ccccccacga cctcgcccgt cccaggagag ccgtcccgca cggcgaggac
    15421 gctgcaggaa agcagggggc cgatctcctc gccgccgagg agcggaacga gctcctcctg
    15481 caacgccttc tcggggtcgc gggggcggtg gtcgggatgg ccgggcgggt aggccgcgaa
    15541 ccacgcgggg aggatctcgg cgggcggccg atcacagggg actatcagaa agccgtccgg
    15601 agcggtgtcg gtgaccggcc gggcgagcgg cagatcgcac cgcatcacgt gcatgtgccg
    15661 cagcagccgc gcgcctcggt cgagcagggc ctgaccgaga tcgaccggcg cggagaccgc
    15721 ccagccgggc atccgcgacg tgatcgcgtc ggcggctccc cggccgacgt cctcgatcgc
    15781 gtacgcccag gggcggccgt cgcggacgcc ttccagataa ctgaacaccg ggacgccgcc
    15841 ggggccgggc attctccgcc gctcctcggt catatcgcga ggttcgcgca ccacggcccg
    15901 atcggcaacc ggtcgaggtc acgcgtccgc gtcgtccccg tcatccgcgt cgtccccgtc
    15961 ctcccagcgc agcaggtctc ccggctggca ctccagcgcc tcgcagagcg cggcgagtgt
    16021 cgagaagcgc accgccttgg cgcggccgtt cttgagcacc gccagattgg cgggtgtgat
    16081 cccgacgcgg tccgcgagct cgcccacgga catcttccgc ttggccagca gcacgtcgat
    16141 ctcgacgacg atcggcatca gatcacctcg tccagctcgg cctgcatccg cgccgcctcg
    16201 atgtcgcgcc tgacagcctg ggcgagcagc atccgcagca cgagcacgat gagcgcgacc
    16261 cccagcaccg ccacgccggc cccgcccacc aggaggacca cgcccggggg gacggcttcg
    16321 cccggagcca ggacgacccc gagcgcgaag atcaggaggg cggccgccac gaaagcgccg
    16381 atcacgacgt tcacccatcg gaaggcgtcg tgggagaaga ccgttcctcg ccgcaccatc
    16441 gtcaccagac gccacacgct gaccaggacg acctcgaccg tcacgacgcc caggaacgtg
    16501 atcgccagga acggggagcg caggtaggcg tagtccgggt cgagtctctc caggtcggag
    16561 gcgaggagcg gcaccatcac ggcctgcacg aacaccgagc cggcgagcag tgccacgagc
    16621 acggcacgca gcgcgagcac tgtcagctgt ctcatcgtct ctccttcaat cgaagcacga
    16681 tagaaatcta tcgataatcg ataggaagaa gcaaggcgtg ctcccggccg atgctcggga
    16741 ccgctcccta gacgccctgg ggcaggcgga acaggcggcc ggggtcgtac gccgccttga
    16801 cccgggccag ccgggcggcg ttggcgccgt agtactgctg ccgccagttc ttgagctccg
    16861 gatcgatgta gttcacgtac gcgtggtcgc cgaaatacgg ccgcatggcg gcgtgggcgg
    16921 cccgggccca ggcggccgcg ccggagaagt gggagtagta ctgcacgctg aacaacgcct
    16981 tgcggtgggg gaaggcggtg gcgtcgggcc ggacccgggc gacggcgccg ccgagcgcgt
    17041 cgagcatcac cgtgtgccga cccggcgcgg cgacccgggc cagcagcgcc ttgatcccgg
    17101 ccgacgacag cggcgtgtac gcgaagtgcg acttggccga gaacgagtcg cggaccagct
    17161 tgcccctcgc gttctgcccg ggaagcgtgc ccggacggtg gcactgggcc accgacatcg
    17221 acgcgcagcc cgcctccacc atcatcgcgt ggtcgtaggc ggacgtcgcg acgtagcggg
    17281 tcgacgggcc cgatccgacg cggtcgacga gcttctgcag caggttctcg cacgctgtcc
    17341 tgccaccgag gtagaggccg cccaccatca cgtcgagcga cgggtcgtgg tcgagatggc
    17401 agttggacca catcgcgtca ggcgcggcgg gcgcccacgc ctgccacgcc ttcagcacgg
    17461 ccgcggcctt cgaccagggc cagtgcagga agaacagggt cacggaacgc gtcggatggg
    17521 tccggaacgt gaacgacgtc gccacgccga agttgccgcc gccgcctccc cgggaggccc
    17581 agtagaggtc cgggtgcgag ctcggcgagc aggtcacgac cttcccgtcc gccgtgacga
    17641 ccttcaaaga ctccagcgcg tcgcaggtca ggccgtactg ccgcgacacc acgccgatgc
    17701 cgccgcccag cgtgagcccg gccaccccga ccgtcgggca ggaccccgcc gggatgctga
    17761 cgccgtgcgc ggccagcttg gcgtacacgt cgaccagccg cgccccggcg ccgaccgtgg
    17821 cgtggccgcc cgaggaggac acgccgctca tcggcgacac gtcgacgacg agcccgctgc
    17881 ccgtggacca gcccgcgtag ctgtggccgc ccgaccggga ggtcaccggc acgccgtacc
    17941 gccgggcgaa cgccaggcac tccgacacgt ccgccgccgt cgtgcagtag gccaccccga
    18001 ccggccgtgc ggagtcgaag gccgagttga acacgcggcg cgcgttgtcg tacgacgcgt
    18061 cgccggggcg gatcagcttg ccgtccagcc cccgcccgag cgcggaccag tcggcgggac
    18121 ggggacccgc ggcggcgaag gccgtgccgg aaagggcggt ggccccggca agggccgaga
    18181 cgcgaaggaa actccgtctg tcgatcatgg tcgtactccc gaggtggtga tctacctcgt
    18241 tgagacgctc atggaatcga tccggttggt tacaaggtcg tcacgtcgcc ccggtgcgga
    18301 agggccgcgc cggagacccg ggggccgccc ggcgtgcccg acgtcgtcac ggacggctcc
    18361 gtctcctcct cggagcgttt ccatccgtga ccgcccggcg ccggcggccc gcggacgatc
    18421 tcgaagccgg cgatctcggg acgggcggtc tcggggcgga cagtctcggg gtggacggcc
    18481 ccgccagggt gaacgtgccc tccctgcgga ccgtgtgcca gcgcagccgg gcccccagaa
    18541 ccgcggtggc caccgactgg atgacgacca ggtacatcag ctgccggtag acgaactgct
    18601 gcaacggcag cacccacagc accgaggccc gttcgccgtc caggcgcagc gcgtaccagc
    18661 cggtgagcgc ctgcaccgcg acgaagccgg cccacaccgc gaccacgggc agcgggtcgc
    18721 cgacgaacag cccgtagagg gccatgacgt cgacgacggg ggccagcaac ggcaggatca
    18781 cctgaaacag ggtgagatat ccgaggcatc gccggccgaa gggacggcgc tccgcgacgg
    18841 ccccgcgatg cttccagatc gcctgcagcg tgccgtagca ccaccggtac cgctgccgcc
    18901 acagctggcc gagcgaggcg ggcgcctcgg tccacgcgcg cgcccgctcc tcgtagacca
    18961 cccgccagcc cccgcggctg atcgccatgg tcaggtcggt gtcctcggcg agcgtgtccg
    19021 cgctgacccc gccggccgac gcgatcgcct cgcggcggaa tgcgccgatc gcccccggca
    19081 ccgtcgccat gcagccgagc aggtcgaacg cgcggcggtc caggttgaac ccgacgacgt
    19141 actcgatgtg ctgccagcgg ccgatcatgc cgcgccggtt gccgaccttg gtgttgccgc
    19201 tgaccgcgcc gacggttccg tccgcgagcg gccgtacgag gtgaccgatg gtcgggggct
    19261 cgaagacggt gtcgccgtcg accatgacca gaatgccgtg ggcggagtgg gcgatgccgg
    19321 tggtgagcgc gacgggcttc ccggcgttcg gctgccggat cacccggacc ccgggcaggc
    19381 cgagcgaggc ggcgatcgct cccgtctcgt cggccgagcc gtcgtccacg acgacgacct
    19441 cgaccgggcc ggggtagtcg gtcgcgacga gcgaccggac cgtcgcctcg atccccgccg
    19501 cctcgttgta cgcgggcacg atcaccgaga ccggcggcgc ggccgtcccg tgggggacga
    19561 cggcgttggc ggatctcccg cgcgtcctgc gggcgtgcgc ccacgccagc gcgacgaaga
    19621 gggccagccg gagcagggtg agcacgccgg ccgcggcgag gaaccagccg agcgcctcga
    19681 cgaaggcgaa ggaggcgcgc tgggcgaacc ccaggatcgc gccgaggacg cgctcgtcgg
    19741 cggaggcggc ggtgtgcgcc gtggggagcc cgacggcgtc cgtgagggtg gtggcggcgt
    19801 atcccttctt ctccagccgg gtgagcagcc ggtcgacggc ggccagcgtc cgggcgcggt
    19861 cgccgcccga gtcgtggaac atgatcactg ctccctcgcc ctcgaccgtg cgcgcgaggg
    19921 acgcgaggac catctcgttc acgggcgggc ggctccagtc ctgggtgtcc acgtcggtga
    19981 acgtcacgag gtatccctcg tcgccgagca gccgcatggt ggcgagctgc cggtatccgg
    20041 ccgctccggg gcccgaggag tacggaatgc gggcgaggcg ggtgtggatc cccgccgccg
    20101 cggccagcgc cttctgcgtc agggacatct ccacgcgggc ccgccaggcc ggcaccgcgc
    20161 ccaggtcggc gtgggtgtag gtgtggttgc cgatctcgtg cccctcggcg accatgcggc
    20221 gggtgagctc ggggtgctcg gcgacgtggg ctcccaggac gaagaaggtc gccttcgcgc
    20281 ggtgctcgcg gagcaggtcg agcagcaggg gcgtccacct cggatcgggt ccgtcgtcga
    20341 aggtgagcgc cacccggcgg ggcctgggcc gtgcgctgag cggccgggac cccgagacgt
    20401 tgaccagggg gccgccggag cggatctgtt ccaactcggc ggagtcgccg aagtcggccg
    20461 ggggcggctg ggtctcgccg acgacgttgt gcgcgtacgc gtcgagcagc agcgccccgg
    20521 ccatgagtag cgcggcgatc gcgacgagga accagtggcc gcgcggctct gccgttctgc
    20581 gctctgccgg tctgcgctgt cgtctcatcg acgcgtcact gggcggcccc gggctgctgc
    20641 ggaggcgtct ggacggtgcc gggttccgac gccgggggcc gcgtcgcctc ctcggcgggc
    20701 gccgtggact gcacgacctc ggaaacctgc ggcgcgggcg tcggctcgcc gggcgcggag
    20761 atctccacat ccggctccgg gagcgaggaa gcggaaggcg tcctgctcgg cctcgggctc
    20821 ttccgggcgg agggggaggg cgccctgctc ggcagcctgc gcgcggaggg agtccgccgc
    20881 gccgggggcg ccgtcgcgcg cggcgtgccg ttcgccgccg cctcgtcccg gggggcacgc
    20941 ctgcgctcgg acccgcggga cggagtggtg gagcccgcgg gggagcgttc cacgaccggc
    21001 tgcacctgcg tgccgggcca tctcatcggg ggcagctccg ggcccgccag cgctccgctc
    21061 accagcgtga gggtcagcgc gaggacgacg atcgccccgc cgaccgcggc ggctgtcaag
    21121 atctttgccc ggcgcccgct ctggtccacg aagacggccg cgcgctccgg acgtcgatct
    21181 tccacgacgc atgatcgtac gtgaatcgaa agcagcttcg agaagtccgg gccattttgt
    21241 gatcaggcat tcgcgatttc ccgatgcccg gtgcgaggtc ctcccggcgg cgggtggtcg
    21301 tcctggtggc tgatgcgcat gagacccctc ggaggaggcc tggctggtta aatgtgacaa
    21361 ggtcaacccc ctgatcgcga gcgcgcgacg aagttgacgt ttgtgccgtt atggggtggt
    21421 atcgggggcg gtggtgccgg gctttcggtc aatggggacc gggagggccg cgcccatcgt
    21481 ggaggagtgg cgcatgcctg cgacgccgta cggccgagcc gggtccgggg acaggctgcc
    21541 cccctcgcgc agcttcggcg aggagggcgg gcgtctgtcc tacggcggct accttcgcct
    21601 gcccgagctg ctcgcccagc aggagcggcg gtccggggcc ggcgacgagt tgctgttcat
    21661 caccgttcac caggtctacg agctgtggtt caagctgctc ctgcacgagc tggagcggat
    21721 cagggacgcg atgatcgagg gcgcgctgtg gcgcgccagg caactgttcc gccgagtgca
    21781 cgcggcggag aaggtcctgg tcgaccaggt ccaggtgctg gagaccatga cgccgcagga
    21841 cttcctggag ttccggtcgg tcctcgcccc cgcgagcggt ttccagtcgg tgcagttccg
    21901 cgagctcgag ttcctctcgg gcgccaagga cccggcgtac ctcggccggc tgagggacgc
    21961 gagcgaggcg gaactcgcca ggctgcggcg gcggctcgcc gagccgacgc tgtgggacgc
    22021 ctacctcacc gccctgtccg ggc
//
