LOCUS       NZ_BMMN01000001        21134 bp    DNA     linear   CON 22-DEC-2024
DEFINITION  Microbispora bryophytorum strain CGMCC 4.7138 sequence01, whole
            genome shotgun sequence.
ACCESSION   NZ_BMMN01000001
VERSION     NZ_BMMN01000001.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Microbispora bryophytorum
  ORGANISM  Microbispora bryophytorum
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Streptosporangiaceae; Microbispora.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 1141878)
  AUTHORS   Sun,Q. and Zhou,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 202X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014645855.1-RS_2024_12_22
            Annotation Date                   :: 12/22/2024 07:39:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,203
            CDSs (total)                      :: 7,136
            Genes (coding)                    :: 7,048
            CDSs (with protein)               :: 7,048
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 16 of 88
            Pseudo Genes (incomplete)         :: 78 of 88
            Pseudo Genes (internal stop)      :: 7 of 88
            Pseudo Genes (multiple problems)  :: 11 of 88
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:18:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 173325
            Orig. end                         :: 194459
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMMN01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21134
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..21134
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21134
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11134](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11134
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     misc_feature    complement(167..178)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     misc_feature    complement(537..551)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.35"
                     /tool="antismash"
     misc_feature    537..552
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.67"
                     /tool="antismash"
     misc_feature    complement(538..551)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.44"
                     /tool="antismash"
     gene            1294..1647
                     /locus_tag="IEY80_RS00870"
                     /old_locus_tag="GCM10011574_01760"
     CDS             1294..1647
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013130567.1"
                     /locus_tag="IEY80_RS00870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_01760"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_142567490.1"
                     /transl_table=11
                     /translation="MTEQEDGPLLRPYTLTRGRTRPSGPEFDLMTVIRTAPAAYSGISG
                     LAPEHWRILQLCRIPVSVADLASELGLSLNVVRILLSDLRDQGLISARPQATVAQLPEE
                     RILREVIQGLQAL"
     gene            complement(1696..2100)
                     /locus_tag="IEY80_RS00875"
                     /old_locus_tag="GCM10011574_01770"
     CDS             complement(1696..2100)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY80_RS00875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10011574_01770"
                     /product="hypothetical protein"
                     /protein_id="WP_142567491.1"
                     /transl_table=11
                     /translation="MDANSQGAAELLATLMRTAARFSEMGRSVSRDFFPHVRVEPVSDL
                     AGPAVRLGAALALPGHDLVFETAVAVGGEMFSVRGGLVLDGEEEILVLPSVETADAVAC
                     AALLDRYADELTTPARWHVQRLLESCETDW"
     gene            complement(2180..2614)
                     /locus_tag="IEY80_RS35765"
                     /old_locus_tag="GCM10011574_01780"
     CDS             complement(2180..2614)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY80_RS35765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10011574_01780"
                     /product="hypothetical protein"
                     /protein_id="WP_223852882.1"
                     /transl_table=11
                     /translation="MRKIVAVAVLAAMTMLGTVAAVATVAAGTGGHPTIGPWAGSQPQA
                     PALPKGGVKRQEVSQEQYDILVGQCRYAKTPEARDRCHTQVREQYKVGAFNPGLDCRAY
                     SGVSVCGVLELSAPQRSCVEESVGGGLTRRRAEVECYAFR"
     misc_feature    complement(2692..2707)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     misc_feature    2727..2745
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.7"
                     /tool="antismash"
     gene            2876..3241
                     /locus_tag="IEY80_RS00885"
                     /old_locus_tag="GCM10011574_01790"
     CDS             2876..3241
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012894280.1"
                     /locus_tag="IEY80_RS00885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_01790"
                     /product="hypothetical protein"
                     /protein_id="WP_142567492.1"
                     /transl_table=11
                     /translation="MRFVHGITAALVLSGLTVTGAVTGAGASALADAGPQPTSRAVVDG
                     YQVVTLPNANVPNFTRRTVYCPAGKRAVGGGGEAQGNDAVLVGSFPTPDGAGWIALGRQ
                     NSYNTVGISVYAICANA"
     gene            complement(3313..4146)
                     /locus_tag="IEY80_RS00890"
                     /old_locus_tag="GCM10011574_01800"
     CDS             complement(3313..4146)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019144.5"
                     /locus_tag="IEY80_RS00890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_01800"
                     /product="Sua5/YciO/YrdC/YwlC family protein"
                     /protein_id="WP_142567493.1"
                     /transl_table=11
                     /translation="MVISASPRARRSERGLCSACVRELFDRTGRRYLYPLVCCDDCRPP
                     TAATPSAVLCEDCGRESREPDVRRSASVATGCAACGPALWWEAVTGVDALAAAVAAIGA
                     GGVAGVRDLFADQVVCDARSEQALARMDGASGPVRVLVRNVSTAREVANLSAPDIRALV
                     ERAEPATLVRLREPMLPRAVRHATPDVDLFLPRTPLQYLLTASLDGPLAVWDRSSERAD
                     GWPCDGTLTVSGLARAGRQSLTTGLPARLTLGATSSPCVRREPAASPEPSPVSAR"
     gene            complement(4240..4794)
                     /locus_tag="IEY80_RS00895"
                     /old_locus_tag="GCM10011574_01810"
     CDS             complement(4240..4794)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF037150.5"
                     /locus_tag="IEY80_RS00895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_01810"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_142567494.1"
                     /transl_table=11
                     /translation="MEGTPTSRAERRRRTEERILSAARAIFAECGFQRTTIRAVAAAAE
                     VDPALVMQYFGSKQELFEQAVRIPSIPPLDGELDPVEELLGRIGMKTGPLPQATLAMMR
                     SMLTHPDAAEEVRGKLDGQVAQLADAIDSGDAELRAALMVSTMLGVTIAHQLLGLTALR
                     GASPERIAETLRPSLRALADG"
     gene            4897..5394
                     /locus_tag="IEY80_RS00900"
                     /old_locus_tag="GCM10011574_01820"
     CDS             4897..5394
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF07366"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019013.5"
                     /locus_tag="IEY80_RS00900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_01820"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_142567495.1"
                     /sec_met_domain="PF07366 (E-value: 1.6e-09, bitscore: 33.7,
                     seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLTPREVLARYHRAMVDRSADDLADLYAAGALHTFPFRAPLFPA
                     RLEGREEIRALYRATWGASPVRLTEIHDVVVHDAADPEVVTGEWEGTGTVEPDGRPFRA
                     TGLLTLRVRDGEIVETRDYMDVFGTYHAMGRLKDVVAATENWTAENAAAGNPAAGNPAA
                     TA"
     misc_feature    complement(5428..5448)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.79"
                     /tool="antismash"
     gene            5439..5969
                     /locus_tag="IEY80_RS00905"
                     /old_locus_tag="GCM10011574_01830"
     CDS             5439..5969
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012792.5"
                     /locus_tag="IEY80_RS00905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_01830"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_208762020.1"
                     /transl_table=11
                     /translation="MTISGTVVRRAEAADAAALVRLRAVMLEDMGAEVGDDSAPWRASA
                     EAWFARRLGDPEDFAAFVVDDPELGVVSCAAGTCDPHAPGPTNPSGLQGHVFNICTDRR
                     RRRLGLARLCLDALLAWYRTETEVRTIDLNATSYGIELYQSFGFDEPRYPALQLRLGPP
                     LGRGFTSHQRSSR"
     misc_feature    complement(6140..6153)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.08"
                     /tool="antismash"
     gene            6229..6663
                     /locus_tag="IEY80_RS00910"
                     /old_locus_tag="GCM10011574_01840"
     CDS             6229..6663
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF07366"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019013.5"
                     /locus_tag="IEY80_RS00910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_01840"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_167748063.1"
                     /sec_met_domain="PF07366 (E-value: 1.1e-17, bitscore: 60.1,
                     seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEVLRPLDRLRQAINRHDLDALARCFDERAVLVAPDGIAENKEE
                     IASYYGEWMDAFPNMLITPQSVTMFQDTVAVEFTISGTHKGPLLVPGGDVLEGTGRPVL
                     VRSCSFSTVEGGTILSHRLFYDQLEMAAQIGGHLRFGDGP"
     gene            6907..8694
                     /locus_tag="IEY80_RS00915"
                     /old_locus_tag="GCM10011574_01850"
     CDS             6907..8694
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0030245 - cellulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013504.5"
                     /locus_tag="IEY80_RS00915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_01850"
                     /product="glycoside hydrolase family 6 protein"
                     /protein_id="WP_167748064.1"
                     /transl_table=11
                     /translation="MSFGHRRSVRAILTAAAAAVPVAALAAAGPVLGVASADAAVTCQV
                     TYASTQWGTGSGGFTAGITVRNTGERLTGWKLTFTFPRSQKLTQGWSARWTQLAGHVTA
                     ENESWNGTVASGGSVQLGFNGAWTGDNMPPMDFALNGVPCQVIVPGTSPSPPAGPSASI
                     TPSPGGDVPVDNPFAGAKGYVDPGWAADVESSAAKVNEATAAKMRGLKNTPTAVWLDRI
                     AEVGGGSGVTRTLKDHLDTAVEQGAGYITLVLHDLPDRDCRSRVSSAELHERDNGLDRY
                     KAEFVDPVAALLARPEYRNLRVAAVVEPRALADLVVGGALGIYPCVQATGSGVYVTGIR
                     YALDKLSPLPNVYTYLDAGSAGWTGWETDLAALATSVTETVRGTAAGLNSLDGIATNVA
                     DYIPLEEPFLTGPDQTVAGQPIKQSRFIDWNPYLNERDYAVAMRSALIAKGFSSLLGVV
                     VDTSRDGWGGPARPTAASTSLNIDTFVDQSRVDRRPSRAAECNQNGAGLGARPVAAPVP
                     GVDAYQWIKRPGESDGVGGPLLPEDSDRLVDYRCDPNGSLTPGSDGFRPTGALPDAPLA
                     GDWHHEQFVMLVENAYPAL"
     gene            complement(8794..9807)
                     /locus_tag="IEY80_RS00920"
                     /old_locus_tag="GCM10011574_01860"
     CDS             complement(8794..9807)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013618.5"
                     /locus_tag="IEY80_RS00920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_01860"
                     /product="lytic murein transglycosylase"
                     /protein_id="WP_142567498.1"
                     /transl_table=11
                     /translation="MNDQPAVISPPMPQHTMPRHTMPQRTMPRHAMLAAALAAVVVPLS
                     GCGGSVGEAASVAPRESVTAPASERSPASTERPEPAARDLPAPDEAIPKDPTRLADALS
                     RTSGRLRDAIDDWRRTGDPAKGEAPEPVVLLSLYEQRVYRYLARHSTIASRTYGKLPED
                     MAARARDNVTAIRDLLSLAHPVSGPIKIKVEAPQPADALLAAFRRAERRFGVEWEVLAA
                     VMLVETKFGRVRSPSYVGAKGPMQFMPGTWKAYGMGGDIDDTGDALLAAANYLHASGAP
                     GDYRRALYAYNHSQAYVDAVLLHARQMKRDVRNYYAYYTWQVYVITTKGERRLTGP"
     misc_feature    9916..9931
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.15"
                     /tool="antismash"
     gene            10001..11134
                     /locus_tag="IEY80_RS00925"
                     /old_locus_tag="GCM10011574_01870"
     CDS             10001..11134
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013094.5"
                     /locus_tag="IEY80_RS00925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_01870"
                     /product="ThiF family adenylyltransferase"
                     /protein_id="WP_142567499.1"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 7e-18,
                     bitscore: 60.7, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 3.6e-48, bitscore: 160.1,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFEHRPHRYEDGTIRIGGEIYGIAAEIADPYGWAWTALTLMDGT
                     RSLDEIIERLRLAHPELPDPESIVEQLAATRYVEDAAAVPPAGLSERERDRYSRNHAFF
                     RTVDIVPRGHGWETQLRLKSARVVVLGLGGTGCHAAWALAAVGVGTIHCVDPDLVELSN
                     LNRQVLYGEGDVGRPKAEAAVARLRTVNSDISVTGERRHIGSRRELDELIAGYDALALC
                     ADRPTGHDIRVWANRACAAAGIPWAGGGYNGPLVTVGCFAPGAGACYECLSSGEEARRH
                     PGTPVDLGGPGVIATSAGVSGQLVAHALLGLLTGVPVPPVGTIQGVNLIAADHHVWVRH
                     PPRPGCPVCGTRADGSEHNSMHRMTEIDAGRANRTRP"
     aSDomain        10004..10264
                     /aSDomain="Pantocin_Microcin_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing E1-like protein in a
                     pantocin/microcin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_IEY80_RS00925_Pantocin_Microcin_RRE.1
                     "
                     /evalue="1.80E-19"
                     /identifier="RREFam017.1"
                     /label="IEY80_RS00925"
                     /locus_tag="IEY80_RS00925"
                     /protein_end="88"
                     /protein_start="1"
                     /score="60.7"
                     /tool="antismash"
                     /translation="KFEHRPHRYEDGTIRIGGEIYGIAAEIADPYGWAWTALTLMDGTR
                     SLDEIIERLRLAHPELPDPESIVEQLAATRYVEDAAAVPPAG"
     gene            11213..11338
                     /locus_tag="IEY80_RS36875"
                     /old_locus_tag="GCM10011574_01880"
     CDS             11213..11338
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY80_RS36875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10011574_01880"
                     /product="hypothetical protein"
                     /protein_id="WP_263407591.1"
                     /transl_table=11
                     /translation="MNTNEHETEAVDEAVVPAKTTITIRLLDKIETTTSSNSVGN"
     gene            11431..12102
                     /locus_tag="IEY80_RS00930"
                     /old_locus_tag="GCM10011574_01890"
     CDS             11431..12102
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF045158.2"
                     /locus_tag="IEY80_RS00930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_01890"
                     /product="DUF6879 family protein"
                     /protein_id="WP_142567500.1"
                     /transl_table=11
                     /translation="MANAGTVFDDVRQAEARVLSADAYQAEFTEEFKRAPDGVWKLERA
                     QEFFEPDVASWRAMMAGDWDGSLALLEGLREFLVDYYRTRPTARRVRVVETPLTPYLQW
                     ELHVLAVRATAGERPRVLHADAVRELEHPTPLPEIVVLGPTLLYEVRYDEIGAHMGARR
                     ITDPALVGPCLAAIKELYGRGEDVRAYVEREVAPLPPPVITARRRDLLSGYSHHTGVFR
                     P"
     gene            12121..13332
                     /locus_tag="IEY80_RS00935"
                     /old_locus_tag="GCM10011574_01900"
     CDS             12121..13332
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY80_RS00935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10011574_01900"
                     /product="hypothetical protein"
                     /protein_id="WP_142567501.1"
                     /transl_table=11
                     /translation="MVGDASVVRLRDLAFRQDGSQWIVGRPDGDAFVAVPYEGVRAIGL
                     LSAGATVEETERRLRAETGADLDVRGFVRALGELGFLEEPGGPAAPAAPPTFPWLRPGH
                     VRWTLHPLVHLLVAGLIAAGIATAVTRRETLPGWRDLLWSERGTLVLASQIAVGWILIF
                     LHEMAHLSTARAAGVPGRIRLGTRLQFLAVQTEVSGVWLAGRRVRLTVYLAGMATDAAA
                     CSAALLLTAVLGHRPVLSLVALTSFGMLATQFLVFMRTDVYFLLQDLSGCRNMYGDASA
                     YARHLALRVLRRPSPDPLTGLPRRERRALRTYAVLLVAGTAACLGVAFAVTVPATLTLL
                     GRAVGVLAAPADPLSGLDAAAVLLSAVAFQVLWARAWWRRHGPRVRRALRRPGRERVAD
                     QDCA"
     gene            complement(13317..14201)
                     /locus_tag="IEY80_RS00940"
                     /old_locus_tag="GCM10011574_01910"
     CDS             complement(13317..14201)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF016228.5"
                     /locus_tag="IEY80_RS00940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_01910"
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_142567502.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 7.6e-19, bitscore:
                     63.9, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIFITGASGYVGAVVAEHLVRAGHEVVALARSDKARERVEGLGA
                     KAVPGGLRDLDVLRGAAAAAQAVVHTAVDYADPDMGEIERDTLAALLDGLNEGGRFVYT
                     STGLVYPDRQGATVDEDHPVAPETSPQPYKVLGERQVLAAGHVAGTVIRAALVYGRGGS
                     GLLQGLIAAGRQGGTVPYIGDGANAWSSVHVDDLAALYVAAIEHRDAGTVVNAASAERT
                     PIRRIAETVAGLTGAQAVSLTLEQGIAAMGPLAATLTRSSPMDASRARRLFGWAPERPG
                     LIEELTTGSYAQS"
     gene            14364..15215
                     /locus_tag="IEY80_RS00945"
                     /old_locus_tag="GCM10011574_01920"
     CDS             14364..15215
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017542087.1"
                     /locus_tag="IEY80_RS00945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_01920"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_142567503.1"
                     /transl_table=11
                     /translation="MDKLGLARFLRSKRESIDPADVGLPLGRRRRTPGLRREEVAQLAY
                     VSVDHYTRLEQARGRHPSRRVLDGIARALRLSDQERAHLFHLAGEREESRSAEPVSEVR
                     PSTLSLVNRLTDAAAIVVDDMCRVLAWNPLAAALFEDFSALAGQERNVIRRYFLHPDPE
                     RRHYGMSSPERFAVTAVSYLRVAATRYPDSHELNSLIEELVAGSEDFARLWNSQRFHIE
                     RHLHQTVRHPRVGPIELDYDVLTVPDQEQQVVIFTAEPGSPAYESLQFLKVVGAEQVPA
                     EA"
     misc_feature    15275..15290
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.0"
                     /tool="antismash"
     misc_feature    complement(15277..15290)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.69"
                     /tool="antismash"
     gene            15358..15786
                     /locus_tag="IEY80_RS00950"
                     /old_locus_tag="GCM10011574_01930"
     CDS             15358..15786
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890617.1"
                     /locus_tag="IEY80_RS00950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_01930"
                     /product="hypothetical protein"
                     /protein_id="WP_142567504.1"
                     /transl_table=11
                     /translation="MTHEEKRAWIRLVVAVIAYAAYVVAVLRRADGGPLPDVPYAAALL
                     WTIGGAIVAAILAEIGMAIVNPRASRVIDVRDKEIGRLGDYTGQAFVAIGALAAMLMAV
                     AEWDRFWIANVIYLFFVLSAVLSDVTKIILYRRSVPEW"
     misc_feature    15460..15462
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            15780..16013
                     /locus_tag="IEY80_RS00955"
                     /old_locus_tag="GCM10011574_01940"
     CDS             15780..16013
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890616.1"
                     /locus_tag="IEY80_RS00955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_01940"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_030510150.1"
                     /transl_table=11
                     /translation="MVKPTRVTNRIRALRFAHDEMTQAELAERIGVTRQTVIAIEQGRY
                     SPSLEMAFRIARVFGAPLDDVFQYPDLPEETK"
     gene            16010..16999
                     /locus_tag="IEY80_RS00960"
                     /old_locus_tag="GCM10011574_01950"
     CDS             16010..16999
                     /NRPS_PKS="Domain: PKS_ER (13-327). E-value: 1.9e-45.
                     Score: 147.3. Matches aSDomain:
                     nrpspksdomains_IEY80_RS00960_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890842.1"
                     /locus_tag="IEY80_RS00960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_01950"
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="WP_189104851.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 4.1e-18, bitscore:
                     61.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAIVQDTYGPADVLELRDIDRPSIGDEEVLVEVRAAAVDPGVWV
                     LMTGTPYLARAGFGLRRPKVPVRGRDVAGVVTAVGAGVTRFRPGQEVYGTCPTGSLAEY
                     AKAPQARLAPKPADLTFEQAAAVPVSGMTALQAVRDVAGVRPGQRVLVIGASGGVGSFA
                     VQIAKALGASVTGVCAAAKADFVRSLGAGDVIDYTREEIDRDGARYDVVVDTAGNRPLS
                     LLRRALTPRGTLVIVGGGHTAYRFTGGMGRTVRAPLLSLFTGSMFSGRRLRPMFSRERA
                     EHLEELTRLIESGAVVPAIDRAYPLAEAPDAIRHLMEGHPAGKVVVTV"
     aSDomain        16049..16990
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEY80_RS00960_PKS_ER.1"
                     /evalue="1.90E-45"
                     /label="IEY80_RS00960_PKS_ER.1"
                     /locus_tag="IEY80_RS00960"
                     /protein_end="327"
                     /protein_start="13"
                     /score="147.3"
                     /tool="antismash"
                     /translation="VLELRDIDRPSIGDEEVLVEVRAAAVDPGVWVLMTGTPYLARAGF
                     GLRRPKVPVRGRDVAGVVTAVGAGVTRFRPGQEVYGTCPTGSLAEYAKAPQARLAPKPA
                     DLTFEQAAAVPVSGMTALQAVRDVAGVRPGQRVLVIGASGGVGSFAVQIAKALGASVTG
                     VCAAAKADFVRSLGAGDVIDYTREEIDRDGARYDVVVDTAGNRPLSLLRRALTPRGTLV
                     IVGGGHTAYRFTGGMGRTVRAPLLSLFTGSMFSGRRLRPMFSRERAEHLEELTRLIESG
                     AVVPAIDRAYPLAEAPDAIRHLMEGHPAGKVVV"
     misc_feature    16058..16060
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS_motif       16214..16249
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEY80_RS00960_0001"
                     /evalue="3.00E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="IEY80_RS00960"
                     /protein_end="80"
                     /protein_start="68"
                     /score="10.6"
                     /tool="antismash"
                     /translation="GRDVAGVVTAVG"
     CDS_motif       16448..16510
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEY80_RS00960_0002"
                     /evalue="9.30E-06"
                     /label="PKSI-ER_m5"
                     /locus_tag="IEY80_RS00960"
                     /protein_end="167"
                     /protein_start="146"
                     /score="18.2"
                     /tool="antismash"
                     /translation="GQRVLVIGASGGVGSFAVQIA"
     gene            complement(17006..17407)
                     /locus_tag="IEY80_RS00965"
                     /old_locus_tag="GCM10011574_01960"
     CDS             complement(17006..17407)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024966.5"
                     /locus_tag="IEY80_RS00965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_01960"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_142567506.1"
                     /transl_table=11
                     /translation="MTLTADDRTAITDVINLHGHLTDSGDFDGLREVFLPDVVYDVGDL
                     GGGVIVGLAALCDAALALGEGNPVAHHVTNIVVTEAADGRARAISKGIGVNADGTTGSV
                     TYEDTLVRGDHGWRISHRTVRARRIPLTP"
     gene            17501..18097
                     /locus_tag="IEY80_RS00970"
                     /old_locus_tag="GCM10011574_01970"
     CDS             17501..18097
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF044515.2"
                     /locus_tag="IEY80_RS00970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_01970"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_142567507.1"
                     /transl_table=11
                     /translation="MTPSGPEPAPPGRTRRADAARNAALLLAAARELVAESGPEVALDE
                     VARRAGVGNATLYRHFPTRADLLVAMYADEVAELCHQGADLPTGLSPADALFSWLDAFV
                     VHVATKRPLALAATEGATGRRSALFDQWHTSIHTTASGLLRRAQDAGAVRPGLTVTDLL
                     ALAGGAALTATDVAHARRLTALLRGGLETGLETGD"
     gene            18180..19106
                     /locus_tag="IEY80_RS00975"
                     /old_locus_tag="GCM10011574_01980"
     CDS             18180..19106
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018657876.1"
                     /locus_tag="IEY80_RS00975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_01980"
                     /product="SPFH domain-containing protein"
                     /protein_id="WP_142567508.1"
                     /transl_table=11
                     /translation="MTDLQIAVDMPAPQTHERTARATSGWPLLVLALLGLLSPAALVPI
                     GAVLAAGGSGGAGVALIAAGVLLLLAAVVVFTGLTAVAPGEARVIQLLGRYVGTVRTPG
                     LRFVAPFTQKRRVSTRIRNHETDITKVNDADGNPIEMAAVVVWQVEDTAKAVFEVDDFM
                     EFVAFQTETAVRHIAGSYPYDGHDDMLSLRQNAEEITGRLSAEIQARVASAGVEVIESR
                     ITRLAYAPEIAQAMLRRQQAGAIVAARQRIVDGAVGMVEAALARLDEHDVIELDEERKA
                     TMVSNLLVVLCGDRDVQPVVNTGSLYR"
     gene            19121..19363
                     /locus_tag="IEY80_RS00980"
                     /old_locus_tag="GCM10011574_01990"
     CDS             19121..19363
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634332.1"
                     /locus_tag="IEY80_RS00980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_01990"
                     /product="hypothetical protein"
                     /protein_id="WP_142567509.1"
                     /transl_table=11
                     /translation="MATERKSVLLRLDPAVHDALARWAGDELRSTNAQIEFLLRRALAE
                     AGRLPGDAGRIPRRGRPAKKGTPPPEAPTADRPDD"
     misc_feature    19374..19389
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            19379..20005
                     /locus_tag="IEY80_RS00985"
                     /old_locus_tag="GCM10011574_02000"
     CDS             19379..20005
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012852254.1"
                     /locus_tag="IEY80_RS00985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_02000"
                     /product="GPP34 family phosphoprotein"
                     /protein_id="WP_142567510.1"
                     /transl_table=11
                     /translation="MDVPGSLTAQLYLLAYDARKERVVTNHRFPYLLRAAALTDLLLTG
                     RIADDGGKVRVVSEDPLADPVLDGLLHQIAQSGPRPWRHWIGKDGRATVRAVRDELETG
                     RWIRVEPRRPFLVFSTSHVRVRDTRVVKRLTAQVSTALTGPVSRIGDREAALVGLAAAG
                     ELGTILPRASRRAHKQRIALLSERGGPVASALRKVIQQARAASGG"
     gene            complement(20053..20697)
                     /locus_tag="IEY80_RS00990"
                     /old_locus_tag="GCM10011574_02010"
     CDS             complement(20053..20697)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012891874.1"
                     /locus_tag="IEY80_RS00990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011574_02010"
                     /product="HNH endonuclease family protein"
                     /protein_id="WP_223852883.1"
                     /transl_table=11
                     /translation="MRRTLQIAVLSLAVLPITAVSTAPPAAADARGRADAGAPARRMLA
                     QLKVAKPLSLRGYSHRRFQPRWAHHKGECDAREVILARQGRGVRRNGACQAVKGVWHSP
                     YDGKVLKSVKQIDIDHVVPLAYAWRSGAKRWSQAKRRAFANDLSRPELVVVSHAVNMAK
                     GGQGPQSWRPPRRASWCRYATSWVAVKHHYRLFVTRAEKVALLNMLRTCGR"
ORIGIN
        1 ggcgatcgcc tggccgacga cggcccaggc cctgacccgt cagctcaccg agacgaccgg
       61 cgcggccgcc ggcgtcaccg ccgcccgcgc cgcgccgctg gcgcagagcg tgctctggga
      121 catcggcatc gtcggcgggc tcggcctcgc ggccgtgctc gcgaccgcgt tcatctcctt
      181 ccggttcgcc cgtacggtga ccggcgagct gagcatgctg caccgggccg cggccgacct
      241 ggccggacgg cgactgcccg acctggtacg acggctgcgg cgcggcgagg acgtcgacgt
      301 ggcggccgag acgccgccga tggcccaggc cagcggcacc gtcgagatcg agaacgtcgg
      361 ccgcgccttc acctcggtgc agcacaccgc gatcgaggcg gccgtcggcc aggccgagct
      421 gcgcaagggc gtcaacaagg tcttcctgaa cctggcccgg cgcagccagt cgctgctgca
      481 gcggcagctc ggcatgctgg acggcctgga gaaggagatc accgaccccg acctgctgga
      541 acggctgttc ggcgtcgacc atctcaccac ccgcatgcgc cgccactcgg agggcctgat
      601 catcctgtcc ggcgccgtgc ccggccgcgg ctggcgcaac ccggtccggc tgtacgacgt
      661 ggcccgcgcc gccaccgagg aggtggagga ctacctgcgg gtcgacgtga acatgccgca
      721 cgggtactcg ctcgcgggcg gcagcgtcac cgacgtcgtc cacctgctcg ccgagctgat
      781 cgagaacgcc acggtcttct ccccgccgca gacccgcgtg caggtcaggg gggagctggt
      841 cgcccggggc ttcgccatcg aggtcgagga ccgcgggctc ggcatcccct cggaggagct
      901 ggcgcacatc aacgcgcggc tcgccgaccc gccggagttc gacctggccg acagcgacag
      961 gctcgggctg ttcgtcgtcg ggctgctggc ccggcggcac aacatccgcg tctcgctgcg
     1021 cacctcgccg tacggcggga ccagcgccgt gctcctgctc ccgcaggaga tcgtggtgga
     1081 gaacgacacg agggaaccga cggtcgagcg cctcgcccag ccggaggccc cgccccccgc
     1141 cctggccctc acgccgccga tcggcggcgg cggcgcccag gattccctgc cccgccgggt
     1201 gcggcaggcc aacctggcgc cgcagctcat ggaggagcag ggtgacctgt tctcctcctt
     1261 ccaggcgggc tggcgacgcg ctcaggagga ctcgtgaccg agcaggagga cgggccgcta
     1321 ctgcgtccct acacgctcac ccgtggccgt acgcgtccga gcgggcccga gttcgatctg
     1381 atgaccgtca tcaggacggc tcccgcggcg tacagcggga tctccgggct ggcccccgag
     1441 cactggcgga tcctgcagct gtgccggatc ccggtgtccg tggccgacct ggcctcggag
     1501 ctcggcctgt cgctgaacgt cgtgcgcatc ctgctgagcg acctgcgcga ccaggggttg
     1561 atcagcgcgc ggccgcaggc caccgtcgcc cagctgcccg aggaacgcat cctccgcgag
     1621 gtgatccagg gactccaggc gctgtgaggc gtcgggagtc cccctcgcgg ggcgtcgccc
     1681 gctcttaccg gtccgtcacc agtccgtctc gcaggactcg agaagccgct gcacatgcca
     1741 ccgggccggt gtcgtcagct cgtcggcgta ccggtccagc agggccgcgc acgccaccgc
     1801 gtcggcggtc tcgaccgacg gcagcaccag gatctcctcc tcgccgtcga gcacgaggcc
     1861 gccccgcacg ctgaacatct ccccgccgac cgcgacggcg gtctcgaaca cgaggtcgtg
     1921 ccccgggagc gccagcgcgg cgccgagccg tacggcgggc ccggccaggt cggagacggg
     1981 ctcgacgcgg acgtggggga agaagtcgcg ggagacggac cgtcccatct cgctgaaccg
     2041 cgccgccgtt cgcatcaacg ttgccaggag ttcggcggca ccctgactgt tggcgtccac
     2101 ccccgcaggg tagatcatgg aaagttgcgg tttggccaat atttaggttg gaccggagat
     2161 ttcccctaaa agggcggcct cagcgaaagg cgtagcactc cacctcggcc cgccggcggg
     2221 tcagcccgcc gcccaccgac tcctcgacgc aggaacgctg cggggcgctg agttcgagca
     2281 cgccgcagac gctgaccccg gagtacgcgc ggcagtcgag gcccggattg aacgcaccca
     2341 ccttgtactg ctcgcgcacc tgcgtatggc agcggtcccg cgcctccggc gttttcgcgt
     2401 agcggcattg gccgacgagg atgtcgtact gctcctggct cacctcctgc cgcttcacgc
     2461 cccctttggg aagcgcgggc gcctgcggct gactcccggc ccacgggccg atcgtcgggt
     2521 ggccgccggt cccggcggcc accgtggcga ctgcggcgac cgtgccgagc atggtcatcg
     2581 cagcgagcac ggcgacagcg acgatctttc tcatggcgat cctcccgagc aggaacgtac
     2641 ccacgggcga acggccgccc ccctgcgccg cgccgggccc gcatggacgg tcgtgacctg
     2701 cgtcacatcg aagtcgacgc atgcaataca ggaagtaaat acaccattgc gaagtgtgac
     2761 gacggatgat caagggtaag tgaggccacg gaaccgacgg ggacggcgtt gacgccgttc
     2821 gcaacccgtt cttcggttcg aaatccggtc atttccgaca caacggagct tttacgtgcg
     2881 atttgttcac ggaatcacgg cagcgctggt cctcagcggc ctcactgtca ccggcgcggt
     2941 caccggcgcg ggcgcgagcg cgctggccga cgcgggcccg cagcccacgt cccgcgccgt
     3001 cgtcgacggc taccaggtcg tgacgctgcc caacgcgaac gtgccgaact tcacccggcg
     3061 caccgtgtac tgccccgcgg gcaagcgcgc cgtgggcggc ggcggcgagg cgcagggcaa
     3121 cgacgcggtc ctcgtgggca gcttccccac cccggacggc gccggatgga tcgcgctcgg
     3181 ccggcagaac tcctacaaca ccgtcggcat cagcgtctac gccatctgcg ccaacgcctg
     3241 atcaagtcac acgctgcgcg ggggagcggg cagcgcccgc tcccccgcgc gcatgacgcc
     3301 gtgacgcgcc ggtcagcgag cgctgacggg cgacggctcc gggctcgcgg ccggttccct
     3361 cctgacgcag ggggaggagg tcgcgcccag cgtcaggcgg gccggcaacc ccgtcgtcag
     3421 gctctgacgg ccggcgcgtg ccagcccgct cacggtcagc gtcccgtcgc acggccaccc
     3481 gtccgcccgc tcggacgacc ggtcccacac ggccagcgga ccgtccagac tcgcggtgag
     3541 cagatactgc agcggggtgc gcggcaggaa caggtcgacg tcgggcgtcg cgtgccgtac
     3601 ggcccggggc agcatcggct cgcgcagccg caccagcgtg gccggctcgg cacgctcgac
     3661 cagcgcgcgg atgtcgggag cggagaggtt cgccacctcc cgggccgtcg agacgttcct
     3721 gaccagcacc cgcaccggtc ccgacgcgcc gtccatgcgg gccagcgcct gctcggacct
     3781 ggcgtcgcag acgacctggt cggcgaacag gtcgcgcacc ccggccactc ccccggcccc
     3841 gatcgccgcg acggccgccg ccagcgcgtc cacgcccgtg acggcctccc accacagggc
     3901 ggggccgcag gccgcgcagc ccgtcgcgac ggaggccgat ctgcggacgt ccggctcccg
     3961 gctctcccgt ccgcagtcct cgcacaggac ggccgagggc gtcgcggccg tgggcgggcg
     4021 gcagtcgtcg cagcagacga gcggatacaa atacctgcgg ccggtccggt cgaacagctc
     4081 acgcacgcag gccgaacaga gcccccgctc actccgccga gcgcgggggg atgccgagat
     4141 gaccatggaa gcggcactgc ccccggccgg ccgccctaat cacactggtc acatgattct
     4201 caggagcgcc tgacctgcgg tcacgccgta cgggacggct cagccgtcgg cgagggcgcg
     4261 cagggacggg cggagcgttt cggcgatccg ttcgggagac gcgccgcgca gggccgtgag
     4321 gccgagcagt tgatgggcga tcgtcacgcc cagcatcgtg ctgaccatca gggccgcccg
     4381 cagctcggcg tcgccggaat cgatcgcgtc cgccagttgc gccacctggc cgtcgagctt
     4441 gccgcgcacc tcctcggccg cgtcggggtg ggtgagcatg gagcgcatca tcgccagcgt
     4501 cgcctgcggc agcggccccg tcttcatgcc gatcctgccc agcagctcct cgaccgggtc
     4561 cagctcgccg tccagcggcg ggatcgacgg gatccgcacg gcctgctcga acagctcctg
     4621 cttcgacccg aagtactgca tgaccagggc cggatcgact tccgcggccg ccgccacggc
     4681 ccggatcgtc gtgcgctgga agccgcactc ggcgaagatc gcccgcgcgg cggacaggat
     4741 gcgctcctca gtgcggcgcc ggcgctctgc ccggctcgtc ggcgtcccct ccacgggacg
     4801 actctaccgg cgttgaccac atcggcccgt tcgctctaca gtcgttgagt caacaagtgt
     4861 tgagcgaagt gcttttccac tgatcggagc gaacgaatgc agctcacccc gcgcgaggtc
     4921 ctggcccgct atcaccgggc gatggtcgac aggtcggccg acgacctcgc cgacctctac
     4981 gccgccggcg cccttcacac gttcccgttc cgggcgccgc tgttccccgc ccggttggag
     5041 gggcgggagg agatccgcgc cctctaccgc gcgacgtggg gcgcgagccc cgtacggctc
     5101 accgagatcc acgacgtcgt cgtccacgat gcggccgatc ccgaggttgt caccggcgag
     5161 tgggagggca ccggcacggt cgagccggac ggccggccgt tccgggccac gggcctgctg
     5221 accctgcgcg tacgggacgg cgagatcgtg gagacgcgcg actacatgga cgtgttcggc
     5281 acctaccacg cgatgggccg gctgaaggac gtcgtggccg ccacggagaa ctggactgcg
     5341 gagaacgccg ccgccgggaa ccctgccgcc ggcaaccccg ccgccacggc ctgatcgggg
     5401 tcgcacgcct gcccgcgggc gcggccacaa tggtgaccat gacgatctcg gggaccgtgg
     5461 tccgccgggc ggaagcggcg gacgccgcgg ctctcgtccg cctgcgcgcc gtgatgctgg
     5521 aggacatggg ggcggaggtc ggggacgaca gcgcgccctg gcgggcgtcg gccgaggcgt
     5581 ggttcgcccg gcggctgggc gatccggagg acttcgccgc gttcgtggtg gacgacccgg
     5641 agctcggcgt ggtgagctgc gcggccggca cctgcgaccc ccacgctccg gggccgacca
     5701 acccgagcgg cctgcagggc cacgtcttca acatctgcac cgaccggcgc cgtcgccgac
     5761 tcggcctcgc gcgcctctgc ctcgacgcgc tgctcgcctg gtatcgcacc gaaaccgagg
     5821 tccggacgat cgacctcaac gccacgtcgt acgggatcga gctgtaccag tccttcgggt
     5881 tcgacgagcc ccgctatccg gctctccagc tgcggctggg cccgccgctc gggcgcggtt
     5941 tcacgagcca tcaaaggtcg agccggtagc gagcggtccg gcgcgtcggc acgtgtccga
     6001 gtgtgtggcc gagtgcgcgg ccgagtggtt tccaggtgcg ccgccgaggc cgcgcccgcg
     6061 ggcgctcggg aacgacgccg gtgccccgcc tgagtcatga gtcctccacg acctcacatg
     6121 gcccaccccc tgagctgggc tatcgtgaaa aatgccgccg atgtccgggc gtcgtgccgg
     6181 tcacggcaca gcacaccgac ggccgctcac gtcaagaaag ggagtccgat gtctgaagtg
     6241 ctccgccccc tggacagact gagacaggcc atcaaccgcc acgacctcga cgccctggcg
     6301 cggtgcttcg acgagcgagc cgttctggtg gcccccgacg gcatcgccga gaacaaggag
     6361 gagatcgcct cctactacgg cgagtggatg gacgcgttcc ccaacatgtt gatcacaccc
     6421 cagtcggtga ccatgttcca ggacacggtg gcggtggagt tcacgatcag cggcacgcac
     6481 aaggggccgc tgctcgtccc cggcggggac gtgctggagg gcaccgggcg gcctgtcctc
     6541 gtacgctcgt gcagcttctc cacggtggag ggcgggacga tcctcagtca ccggctcttc
     6601 tacgaccagc tggagatggc ggcccagatc ggcggccacc tccgcttcgg cgacggcccg
     6661 tgacgggtcc tgcgacgcgc tgaatatttc acgggattcg gtcccggccg gcaggtatcg
     6721 gatggcgttt cccgaggtgc cgcacgattt cggcgaactc ggcgcggaaa gggatatttc
     6781 cacttcggcg aatcgtgtac atgagccggg cgattgccga gtctgaggag cgtcggcccc
     6841 cacgcgcgag ccggaccggg cgccggcatg cccgagccgg tcacctcacc ctggagacga
     6901 tctcccatgt ccttcggcca ccgccggtct gtccgcgcaa tcctgacggc cgcggcggcg
     6961 gccgtccccg tcgcagcact ggccgcggcg ggaccggtcc tgggcgtggc gtccgccgac
     7021 gctgccgtca cctgtcaggt cacctacgcg agcacccagt ggggcacggg ttcgggcggc
     7081 ttcaccgccg ggatcaccgt caggaacacc ggcgaaaggc tgacgggctg gaaactgacg
     7141 ttcacgttcc cccgctcgca gaagctcacg cagggctggt cggcccgatg gacccagctc
     7201 gccggccacg tcaccgccga gaacgagtcc tggaacggca cggtggcgtc cggcgggtcc
     7261 gtgcagctcg gcttcaacgg cgcctggacc ggcgacaaca tgccgcccat ggacttcgcc
     7321 ttgaacggcg tgccctgcca ggtcatcgtg ccgggcacgt cgccgagccc gcccgccggt
     7381 cccagcgcga gcatcacgcc gagcccgggc ggggacgtgc cggtggacaa cccgttcgcc
     7441 ggcgccaagg ggtacgtcga ccccggctgg gcggccgacg tggagtcctc cgccgcgaag
     7501 gtgaacgagg cgaccgcggc gaagatgcgc ggcctgaaga acacgcccac cgcggtctgg
     7561 ctggaccgca tcgcggaagt cggcggcggc tccggcgtca cccgcacgct gaaggaccac
     7621 ctcgacaccg ccgtcgagca gggggccggg tacatcacgc tcgtcctgca cgacctgccc
     7681 gaccgcgact gccggtcgcg cgtctccagc gccgagctgc acgagcggga caacggcctc
     7741 gaccgctaca aggcggagtt cgtggacccc gtcgccgccc tcctggccag gcccgagtat
     7801 cggaacctgc gcgtcgcggc cgtcgtcgag ccgcgggccc tggccgacct cgtcgtggga
     7861 ggcgcactgg gcatctatcc gtgtgtccag gcgacggggt cgggcgtcta cgtgacgggc
     7921 atccgctacg ccctcgacaa gctgtcgccc ctgcccaacg tctacaccta tctcgacgcg
     7981 ggcagcgcgg gatggaccgg gtgggagact gacctcgccg cgctcgcgac ctccgtcacc
     8041 gagaccgtgc gcggcacggc ggcgggcctg aacagcctcg acggcatcgc cacgaacgtc
     8101 gcggactaca tcccccttga ggagccgttc ctgaccggcc ctgatcagac cgtggccggc
     8161 cagccgatca agcaaagcag gttcatcgac tggaacccct acctgaacga acgggactac
     8221 gccgtcgcga tgcgaagcgc cctgatcgcc aagggcttct ccagcctgct cggcgtggtc
     8281 gtcgacacct cccgcgacgg ctggggcggc ccggcccggc ccaccgcggc gagcacctcc
     8341 ctcaacatcg acacgttcgt ggaccagagc cgcgtcgacc ggcgtccgtc acgcgccgcg
     8401 gagtgcaacc agaacggcgc ggggctgggc gcccggccgg tggccgcgcc cgttccgggc
     8461 gtggacgcct accagtggat caagcggccc ggcgagtcgg acggcgtcgg cggaccgctc
     8521 ctgcccgagg actccgaccg gctggtcgac tacaggtgcg atcccaacgg ctccctcacc
     8581 cccgggtcgg acggtttccg gccgaccggc gccctccccg acgcgccgct ggcgggcgac
     8641 tggcatcacg agcagttcgt gatgctggtg gagaacgcct accccgctct gtgagcccgc
     8701 gacgcgtcct gcctgacgcc gttcccgagc cggctccaca ggcgcctgcc gccgggcggc
     8761 ggcaggcggc aggcggcggc gcgctcgccg tcgtcagggg ccggtcaggc ggcgctcccc
     8821 cttcgtcgtg atcacgtaga cctgccaggt gtagtaggcg tagtagttcc tgacgtcccg
     8881 cttcatctga cgcgcgtgca gcaggaccgc gtcgacgtac gcctgggagt ggttgtaggc
     8941 gtacagcgcg cgccggtagt cgcccggcgc gcccgacgcg tggaggtagt tggccgcggc
     9001 gagcagggcg tcgccggtgt cgtcgatgtc gccgcccatg ccgtacgcct tccaggtgcc
     9061 cggcatgaac tgcatcggcc ccttggcgcc cacgtagctc ggcgagcgca cccgcccgaa
     9121 cttggtctcc acgagcatca ccgccgcgag cacctcccac tcgacgccga agcggcgctc
     9181 ggcgcgccgg aaggcggcga gcagggcgtc ggcgggttgc ggcgcctcga ccttgatttt
     9241 gatcggaccg ctgacgggat gggcgaggga gagcaggtcg cggatggccg tcacgttgtc
     9301 ccgcgcccgc gcggccatgt cctccggcag ttttccgtac gtccgggacg cgattgtgga
     9361 atggcgggcg agatagcggt agacgcgttg ttcgtacagg gacagcagga ccaccggctc
     9421 gggagcctcc cccttcgcgg ggtcgcccgt gcgcctccag tcgtcgatcg cgtcacgcag
     9481 tcgccccgac gtacggctga gggcgtcggc cagccgcgtg gggtccttgg ggatcgcctc
     9541 gtccggcgcg ggcaggtccc gtgcggccgg ctccggccgc tccgtactcg cgggggaccg
     9601 ttccgacgcg ggcgcggtca cgctctcgcg gggagcgacc gaggcggcct cgcccactga
     9661 gcctccgcat cccgagagcg ggacgaccac ggcggcgagc gcggcggcca gcatcgcgtg
     9721 gcgcggcatc gtgcgttgcg gcatcgtgtg gcgcggcatc gtatgttgcg gcatcggcgg
     9781 tgagatcacg gcaggctgat cgttcatcgt caccaacgta tgccgcgcgg ggacgtttca
     9841 tgttccttca cggcgaagcg gcgccctgcg agagccctgc gagagccgtc cgaggaggcg
     9901 ggaacgtttt acggctgacc gcttttttcc cttctgtaga attcgatgtt gactcacaca
     9961 gttatcgccc agtagtcgtc atcacgtgcg actgccccgc gtgaaattcg agcatcggcc
    10021 tcaccgatac gaggacggca ccattcgcat cggcggcgag atttacggga tcgccgccga
    10081 aatcgcggac ccatacggct gggcgtggac ggccctcacg ctgatggacg gcacccgttc
    10141 tctcgacgag atcatcgagc ggctgcggct ggcccatccg gagctgcccg acccggagtc
    10201 gatcgtcgag caactggccg ccacccgata cgtcgaggac gccgcggcgg tgccgcccgc
    10261 cgggctgagc gagcgcgagc gcgaccgcta cagcaggaac cacgcgttct tccgcacggt
    10321 cgacatcgtg ccgcgcggcc acggctggga gacccagctc cggttgaagt ccgcgcgggt
    10381 cgtggtgctc ggcctgggcg gcacgggctg ccacgcggcc tgggcgctcg cggccgtcgg
    10441 cgtcggcacg atccactgcg tggatcccga cctggtcgag ctgtccaacc tcaaccgcca
    10501 ggtgctctac ggcgagggcg acgtcgggcg gccgaaggcg gaggcggccg tcgcccggct
    10561 gcgaaccgtc aactccgaca tctccgtcac gggcgaacgc cgccacatcg gcagcaggcg
    10621 cgaactggac gagttgatcg cgggctacga cgcgctcgcc ctctgcgcgg accggcccac
    10681 cgggcacgac atcagggtgt gggccaaccg cgcctgcgcc gccgcgggca tcccctgggc
    10741 gggcggcgga tacaacgggc cgctggtcac cgtggggtgc ttcgcgccgg gagcgggcgc
    10801 ctgctacgag tgcctgagca gcggcgagga ggcgcggcgc caccccggca cgcccgtgga
    10861 cctcggcggg cccggcgtga tcgccacctc ggcgggcgtg tccggccagc tcgtcgccca
    10921 cgcgctgctc ggcctgctga ccggggtgcc ggtgccgccg gtcggcacca tccagggggt
    10981 caacctgatc gccgcggacc accacgtgtg ggtccggcat ccgcctcggc ccggctgccc
    11041 ggtgtgcggg acccgggccg acgggtcgga acacaattca atgcaccgaa tgaccgaaat
    11101 cgacgccggc cgtgcgaaca gaaccaggcc ttgactgcgc cggtcaacgg acgaatcatg
    11161 aacgggttct cgcgagaaca tccatgtccc ctccccttcc gagaggaacc ggatgaacac
    11221 gaacgagcac gagaccgagg ccgtcgacga ggccgtcgtg ccggcgaaga cgacgatcac
    11281 catccggctg ctcgacaaga tcgagaccac gaccagcagc aacagcgtcg gcaactgacc
    11341 aagcgccggc cgcggcgtgc gggggtgccg cggggccgcc cgcacgccac ggccggcgag
    11401 agcccgcagc cggaactcag ggagggaagg gtggcgaacg ccggcaccgt cttcgacgac
    11461 gtacggcagg ccgaggcgcg ggtcctgtcc gccgacgcct accaggccga gttcaccgag
    11521 gagttcaagc gggcccccga cggggtgtgg aagctcgaac gcgctcagga gttcttcgaa
    11581 cccgacgtgg cgagctggcg ggcgatgatg gccggcgact gggacgggtc gctcgccctg
    11641 ctggaggggc tgcgggagtt cctggtcgac tactaccgga cccggcccac ggcccgccgg
    11701 gtccgcgtcg tggagacacc gctcaccccc tatctccagt gggagctgca cgtcctggcc
    11761 gttcgggcga cggcgggcga gcggccccgg gtgctgcacg cggacgccgt gcgggagctg
    11821 gagcacccca caccgctgcc cgagatcgtc gtgctcggcc ccactctgct ctacgaggtg
    11881 cgatacgacg agatcggcgc gcacatgggc gcccggcgga tcaccgatcc cgccctcgtc
    11941 gggccctgcc tggccgcgat caaggaactc tacggccggg gagaggacgt ccgggcgtac
    12001 gtcgagcggg aggtcgcccc gctgccgcca cccgtgatca ccgcccggag gcgcgacctc
    12061 ctgtccggct actcgcacca caccggggtc ttccgcccct gaccccgcgc ctggaggccc
    12121 atggtgggag atgcgagcgt ggtgcggctg cgcgacctcg cgttccggca ggacggctcc
    12181 cagtggatcg tcggccgccc ggacggggac gcgttcgtcg ccgtgccgta cgagggggtg
    12241 cgggccatcg ggctgctgtc ggcgggagcg acggtcgagg agacggaacg gcggctgcgt
    12301 gccgagaccg gcgccgatct cgacgtccgc ggcttcgtcc gcgccctggg cgagctggga
    12361 ttccttgagg agcccggcgg accggccgcc cccgccgcgc cgccgacctt tccgtggctg
    12421 cgccccgggc acgtgcggtg gacgctgcac ccgctggtcc acctgctggt cgccggcctg
    12481 atcgccgccg ggatcgcgac ggcggtcacc cggcgggaga cgctgccggg ctggcgcgac
    12541 ctgctgtgga gcgagcgcgg cacgctcgtg ctcgcgtcgc agatcgcggt cggctggatc
    12601 ctgatcttcc tgcacgagat ggcccacctg tcgaccgcca gggccgccgg ggtgccgggc
    12661 aggatccggc tcggcacccg gctgcagttc ctggccgtcc agaccgaggt gtccggcgtg
    12721 tggctggccg ggcggcgggt ccgcctgacg gtctatctcg ccgggatggc gacggacgcg
    12781 gcggcgtgtt cggccgcgct cctcctgacc gccgtgctgg gacaccgtcc cgtgctctcc
    12841 ctggtcgcgc tgacctcgtt cggcatgctg gccacgcagt tcctcgtgtt catgcgcacc
    12901 gacgtctact tcctgctgca ggacctgagc ggatgccgca acatgtacgg cgacgcctcc
    12961 gcctacgccc gccacctggc gctgcgggtg ctgcgccgtc cctcccccga cccgctcacc
    13021 gggctgccgc gccgggagcg ccgcgccctc aggacctacg cggtgctgct ggtggcgggc
    13081 accgcggcct gcctgggggt ggcgttcgcg gtgacggtgc cggcgacgct gacgctgctc
    13141 ggccgggccg tgggcgtgct ggccgccccc gcggatccgc tctccgggct ggacgccgcg
    13201 gcggtgctgc tgtccgcggt cgcgttccag gtgctctggg cgcgggcctg gtggcgcagg
    13261 cacggcccgc gcgtacgacg cgccctgcgc cgcccgggaa gggaacgggt cgccgatcag
    13321 gactgcgcgt aggagccggt cgtcagctcc tcgatcagtc cgggccgctc cggggcccat
    13381 ccgaacagcc gccgtgcccg cgaggcgtcc atcggcgacg aacgggtgag cgtggcggcg
    13441 agcggcccca tcgcggcgat cccctgctcc agggtcagcg acacggcctg ggcgccggtc
    13501 aggccggcga ccgtctcggc gatccgccgg atcggggtcc gctcggccga ggcggcgttg
    13561 acgacggtcc cggcgtcgcg gtgctcgatc gcggccacgt acagcgcggc gaggtcgtcg
    13621 acgtgcaccg acgaccacgc gttggcgccg tcgccgatgt agggcaccgt gccgccttgc
    13681 cgtccggcgg cgatgagccc ctggagcagg cccgatccgc cgcgcccgta gaccagcgcc
    13741 gcccggatca ccgtgcccgc cacgtgaccg gccgccagga cctgccgctc gccgaggacc
    13801 ttgtacggct gcggtgacgt ctccggggcg acggggtggt cctcgtccac cgtggcgccc
    13861 tgccggtcgg ggtagaccag gccggtgctg gtgtagacga accggccgcc ctcgttcagg
    13921 ccgtcgagca gcgccgcgag ggtgtcgcgc tcgatctcgc ccatgtccgg atcggcgtag
    13981 tccacggcgg tgtgcaccac ggcctgcgcc gccgcggcgg cgccgcgcag gacgtcgagg
    14041 tcgcgcaggc ctccgggcac cgccttggcg cccagccctt cgacccgctc gcgcgccttg
    14101 tccgagcggg ccagggcgac cacctcgtgg ccggccctga cgaggtgctc ggccacgact
    14161 gcgccgacgt agccgctcgc accggtgatg aagatccgca tgatcgtgtg ccttccgtga
    14221 ggtcgggtga ccgcggcgcg ttcgtgctcg ccgccggtcg gtgccgaccc caccgtcgcc
    14281 ccgggccgtc ccgcacagcc agggaccgag agtccgtggc tgcgggagtc cgcgcacccg
    14341 atgccgggcg tacggtcaca agcatggaca agcttggcct ggcgcggttc ctccggagca
    14401 agcgggagag catcgacccc gccgacgtcg gcctgcccct gggacgacgc cgccgcaccc
    14461 cggggctgcg gcgcgaggag gtcgcccagc tcgcgtacgt ctcggtggac cactacacgc
    14521 ggctggaaca ggcgcggggc cgtcacccgt cacggcgggt gctcgacggc atcgcccgcg
    14581 ccctgcgcct gtcggaccag gagcgggccc acctgttcca cctcgccggg gagcgggagg
    14641 agagccggtc cgcggagccc gtgagcgagg tgcgcccgag cacgctgagc ctggtcaacc
    14701 ggctgaccga cgccgccgcg atcgtcgtgg acgacatgtg ccgcgtgctg gcctggaacc
    14761 cgctggcggc cgccctgttc gaggacttct cggccctggc cggccaggag cgcaacgtca
    14821 tcaggcgcta cttcctgcac cccgacccgg agcggcggca ctacgggatg agcagcccgg
    14881 aacggttcgc cgtcacagcg gtcagctacc tgcgcgtcgc cgcgacccgc tacccggaca
    14941 gccacgagct gaacagcctg atcgaggaac tggtggcggg gagcgaggac ttcgcccggc
    15001 tgtggaactc gcagcggttc cacatcgagc ggcacctgca ccagaccgtg cggcacccgc
    15061 gcgtcgggcc gatcgagctg gactacgacg tgctgaccgt gcccgaccag gagcagcagg
    15121 tggtcatctt caccgccgag cccgggtccc cggcgtacga gtccctgcag ttcctcaagg
    15181 tcgtcggcgc cgagcaggtg cccgccgagg cctgacccgc gtccgcgtac gtccgtctcc
    15241 ccgctcggcc ggccggggct ccgtcggcgg gttcgatgta aataattctg tacatcacgt
    15301 caaagacggg ttaccttcgt gatgtcaaag atgttgtaca tccgaagggg atcgatcatg
    15361 actcacgagg agaagcgcgc ctggatccgg ctggtcgtcg ccgtgatcgc ctacgccgcg
    15421 tacgtcgtcg ccgtcctcag acgggcggac ggaggcccct tacccgacgt gccgtacgcc
    15481 gccgccctgc tgtggacgat cggcggggcg atcgtcgcgg cgatcctggc cgagatcggc
    15541 atggcgatcg tcaacccgcg ggcctcacgc gtcatcgacg tccgcgacaa ggagatcggg
    15601 cggctcggcg actacaccgg tcaggcgttc gtggccatcg gggcgctcgc ggcgatgctc
    15661 atggccgtgg cggagtggga caggttctgg atcgccaacg tgatctacct cttcttcgtc
    15721 ctgtcggcgg tcctcagcga tgtcaccaag atcattcttt atcgcaggag cgttccggag
    15781 tggtgaagcc cacccgcgtg acgaaccgca tccgcgcgct gcggttcgcc cacgacgaga
    15841 tgacccaggc cgaactcgcc gagcgcatcg gcgtgaccag acagaccgtc atcgcgatcg
    15901 agcagggccg atactcgccg tccctggaga tggccttccg gatcgcccgg gtgttcggcg
    15961 caccgctcga cgacgtgttc cagtatcccg acctccccga ggagacgaag tgaaggcaat
    16021 cgtccaggac acgtacggcc cggccgacgt gctcgaatta cgcgacatcg accgtccctc
    16081 gatcggcgac gaggaggtgc tcgtcgaggt ccgcgcggcc gccgtggacc ccggcgtgtg
    16141 ggtcctcatg accggcacgc cgtacctcgc gcgcgccgga ttcgggctgc gccgccccaa
    16201 ggttcccgtc cggggccgcg acgtcgccgg ggtcgtgacg gccgtcggcg ccggcgtcac
    16261 ccgcttccgg cccggccagg aggtgtacgg cacctgcccg accggctcgc tcgccgagta
    16321 cgcgaaggcg ccgcaggccc gcctcgcgcc gaagccggcc gacctcacgt tcgaacaggc
    16381 cgccgcggtg ccggtctccg gcatgacggc gctgcaggcc gtacgggacg tcgccggcgt
    16441 gcgcccggga cagcgggtgc tggtgatcgg cgcgtcggga ggcgtggggt cgttcgccgt
    16501 gcagatcgcc aaggcgctcg gcgcgagcgt caccggcgtg tgcgcggcgg cgaaggcgga
    16561 cttcgtgcgg tcgctcgggg ccggcgacgt catcgactac acccgcgagg agatcgaccg
    16621 cgacggcgca cgctacgacg tcgtcgtcga caccgcgggc aaccggccgc tgtccctgct
    16681 gcggcgcgcc ctgaccccgc gcggcacgct ggtgatcgtc ggcggcgggc acaccgcgta
    16741 ccgcttcacc ggtggcatgg gacgcacggt ccgggctccg ctgctgtcac tgttcacggg
    16801 gtcgatgttc agcgggcggc ggctgcgccc gatgttctcc cgcgagcgcg ccgagcacct
    16861 ggaggagctg acccggctca tcgagtccgg cgccgtcgtc ccggcgatcg accgcgccta
    16921 tcccctcgcc gaggcgcccg acgcgatccg ccacctcatg gaaggccacc ccgccggcaa
    16981 ggtcgtcgtc accgtgtgac caccctcagg gagtcagggg gatccggcgg gcgcggaccg
    17041 tgcggtggct gatccgccag ccgtggtcgc cgcgcacgag cgtgtcctcg taggtcacgc
    17101 tgcccgtggt cccgtccgcg ttgaccccga tgcccttcga gatcgctcgc gcccggccgt
    17161 ccgccgcctc ggtgacgacg atgttggtga cgtggtgggc gacggggttc ccctcgccca
    17221 gggcgagcgc ggcatcgcac agcgccgcga gtccgacgat caccccgccg ccgagatcac
    17281 cgacgtcgta gacgacgtcg ggcaggaaca cctcgcgcag gccgtcgaag tcgccgctgt
    17341 ccgtgagatg gccgtgcagg ttgatcacgt ccgtgatggc cgtgcggtcg tcggcggtca
    17401 gggtcatcgt cctccccgtt tcatccaagt ggggaactcc ccggttagag ctgttaccgt
    17461 aagtggggaa ctccccggtt agcaagagag ggaagcgcgg atgacgccga gtggtcccga
    17521 gcccgcaccg cccggccgta cgcgcagggc ggacgccgca cgcaacgccg cactgctgct
    17581 cgccgccgcc cgcgaactcg tcgcggagtc ggggcccgag gtcgcgctgg acgaggtggc
    17641 gcggcgggcc ggcgtcggca acgcgaccct gtatcggcac ttccccaccc gcgccgacct
    17701 gctagtcgcc atgtacgcgg acgaggtggc ggagttgtgc caccagggcg ccgacctgcc
    17761 gacggggctc tccccggccg acgcgctctt ctcctggctg gacgcgttcg tcgtgcacgt
    17821 cgcgacgaaa cggccgctcg ccctcgcggc cacggaaggt gccaccggcc gccgtagcgc
    17881 gttgttcgac cagtggcaca cctcgatcca caccaccgcg tccggcctgc tgcggcgggc
    17941 ccaggacgcc ggcgccgtac ggcccggact caccgtgacg gacctgctgg ccctcgccgg
    18001 cggcgcggca ctcaccgcaa ccgacgtggc ccacgcccga cggctcaccg cactcctgcg
    18061 cggtggcctg gaaaccggcc tggaaaccgg cgactgaggg ttcggctccc cggcgagggc
    18121 aggtctggca aaaagtgata tcactttgct agtgtcgtgc cagacaccga ggagaagaca
    18181 tgacagacct ccagatcgcc gtggacatgc cggcccccca gacccacgag cggacggcgc
    18241 gagcgacctc ggggtggccg ctgctggtcc tggccctgct cggcctgctc agcccggccg
    18301 cgctggtccc gatcggagcc gtcctcgcgg ccggcggcag cggcggcgcg ggagtcgccc
    18361 tgatcgccgc cggggtgctg ctcctcctgg cggccgtcgt cgtcttcacc ggcctcaccg
    18421 cggtcgcccc gggtgaggcc cgcgtgatcc agctactcgg ccgctacgtg ggcaccgtcc
    18481 gcacgcccgg cctccggttc gtggcgccct tcacgcagaa gcgccgggtg tcgacccgga
    18541 tccgcaacca cgagaccgac atcaccaagg tcaacgacgc cgacggcaac ccgatcgaga
    18601 tggcggccgt ggtggtgtgg caggtcgagg acacggcgaa ggccgtcttc gaagtcgacg
    18661 acttcatgga gttcgtcgcc ttccagaccg agaccgcggt gcgtcacatc gccggcagct
    18721 acccgtacga cgggcacgac gacatgctgt ccctgcggca gaacgccgag gagatcaccg
    18781 gccgcctgtc ggccgagatc caggcccggg tggcgtccgc cggagtcgag gtcatcgagt
    18841 cgcgcatcac ccgcctggcg tacgcccccg agatcgcaca ggcgatgctg cgccgccagc
    18901 aggccggagc gatcgtcgcg gcccgtcagc ggatcgtgga cggcgccgtc ggcatggtcg
    18961 aggcggcgct cgcccggctg gacgagcacg acgtgatcga gctcgacgag gagcgcaagg
    19021 ccaccatggt cagcaacctg ctcgtcgtcc tgtgcggcga ccgcgacgtg cagcccgtgg
    19081 tgaacaccgg ctccctgtac cgctagaccg caggcgactt gtggcgaccg agagaaaaag
    19141 cgtcctgctg cggctggacc cggcggtgca cgacgcgctg gcccgctggg ccggcgacga
    19201 gctgcgcagc accaacgccc agatcgagtt cctgctgcgc cgggcgctgg cagaggcggg
    19261 acgactgccg ggcgacgccg gtcgcatccc ccggcgcggc cggcccgcca agaaggggac
    19321 cccgcctccg gaggccccca ccgccgatcg gcccgacgac tgaaaggagg gcggtcacgt
    19381 ggacgtcccc ggctccctga cggctcagct ctacctgctg gcctacgacg cccgcaagga
    19441 gcgggtggtg acgaaccacc gcttccccta cctgctgcgc gcggccgcgc tcaccgacct
    19501 gctgctgacc ggccggatcg ccgacgacgg cggcaaggtg cgcgtggtgt cggaggatcc
    19561 gctcgccgac ccggtcctcg acggcctgct gcaccagatc gcccagtcgg ggccccggcc
    19621 ttggcggcac tggatcggca aggacggacg cgcgacggtg cgggcggttc gcgacgaact
    19681 cgagacggga cgctggatca gggtcgagcc gcgccggccg ttcctcgtct tcagcacgag
    19741 ccacgtccgc gtacgcgaca cgcgggtggt gaaacgactc acggcgcagg tctccaccgc
    19801 tctcaccggc ccggtctcgc ggatcggaga ccgggaggcc gcccttgtcg gcctggccgc
    19861 ggcgggagag ctcgggacga tcctcccgcg cgccagccga cgggcgcaca agcagcgcat
    19921 cgccctgctg tccgaacgcg gcggcccggt ggcgtcggcc ctccgcaagg tcatccagca
    19981 ggcccgcgcc gccagcggcg gctgacctcg gggacgaacc cgtccgtccc cgtccccggc
    20041 cgccgggtcc gctcacctcc cgcaggtgcg gagcatgttg agcagggcga ccttctccgc
    20101 acgggtcacg aagagccggt agtgatgctt caccgcgacc cacgaggtcg cgtagcggca
    20161 ccaggaggca cggcgcggcg gacgccagct ctgcggcccc tggcctcctt tggccatgtt
    20221 gacggcgtgg ctcaccacga ccagctcggg gcggctgagg tcgttggcga acgcgcgccg
    20281 cttcgcctgg ctccatctct tcgcgccgga acgccaggcg tacgccaggg ggacgacgtg
    20341 gtcgatgtcg atctgcttca cgctcttcag caccttgccg tcgtacgggc tgtgccagac
    20401 acccttcacg gcctggcacg ctccgttcct ccgcacaccc cggccctggc gggcgaggat
    20461 cacctcccgc gcgtcgcact cccccttgtg atgcgcccag cgcggctgga accgccggtg
    20521 gctgtagccg cggagcgaca acggcttggc gaccttcagt tgcgccagca tgcggcgggc
    20581 cggcgccccg gcatcggccc gcccacgggc gtcggccgcg gccggcgggg ccgtggagac
    20641 agcggtgatc gggaggaccg caagggacag cacggcgatc tggagagtgc gtctcatgga
    20701 gatcatggtt ccagccatac cagtctctct ccacgggccg tgacgatatg cgggtgtcag
    20761 tgcgatccgc gggcgggaat gttcggcgat ctcggatggt tcaaggcgaa cggaagttga
    20821 agattcaatt aggagggcgg ccatgcccgc tgtcaccgcc gacaccctga cgctcccccg
    20881 cgtcgccgca ccggatcccg ccgtcgcggc accacgaccc gttcgctcgg tgacgagtgc
    20941 cgcaggcgat gctggacccg ttcatccaca tcgacggcgt cttcgagcac caggactcca
    21001 acggaggcgg cggcaccatc accaacggcg acacccagtg gatgaccgcc ggggccgggc
    21061 tgctgcacat cgagaagccg ccggagcatc tggtggtctc gggcgggctc ttccacggca
    21121 tccagctgtg ggtg
//
