LOCUS       NZ_BMMM01000022        20168 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces albiflavescens strain CGMCC 4.7111 sequence22, whole
            genome shotgun sequence.
ACCESSION   NZ_BMMM01000022
VERSION     NZ_BMMM01000022.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces albiflavescens
  ORGANISM  Streptomyces albiflavescens
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 160368)
  AUTHORS   Sun,Q. and Zhou,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 100X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014645835.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 03:24:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,828
            CDSs (total)                      :: 9,745
            Genes (coding)                    :: 9,386
            CDSs (with protein)               :: 9,386
            Genes (RNA)                       :: 83
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 359
            CDSs (without protein)            :: 359
            Pseudo Genes (ambiguous residues) :: 0 of 359
            Pseudo Genes (frameshifted)       :: 102 of 359
            Pseudo Genes (incomplete)         :: 321 of 359
            Pseudo Genes (internal stop)      :: 17 of 359
            Pseudo Genes (multiple problems)  :: 80 of 359
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:54:32
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 103151
            Orig. end                         :: 123319
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMMM01000022.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20168
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="CDPS"
                     /region_number="2"
                     /rules="CDPS"
                     /tool="antismash"
     cand_cluster    1..20168
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /kind="single"
                     /product="CDPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20168
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[<10000:10168](-)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<10001..10168)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
     gene            200..478
                     /locus_tag="IEY95_RS41260"
                     /old_locus_tag="GCM10011579_084050"
     CDS             200..478
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006601789.1"
                     /locus_tag="IEY95_RS41260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_084050"
                     /product="SHOCT domain-containing protein"
                     /protein_id="WP_189191383.1"
                     /transl_table=11
                     /translation="MMWYDGGWGWGGWFAMAIFPVLFLVLLIAGVVMLVRYVTGSRHSH
                     QGGPPPSPGEPGWGSKRAEDLLAERFARGEIDEDEYKRRLTLLREHQ"
     gene            complement(733..1428)
                     /locus_tag="IEY95_RS41265"
                     /old_locus_tag="GCM10011579_084060"
     CDS             complement(733..1428)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016823479.1"
                     /locus_tag="IEY95_RS41265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_084060"
                     /product="DUF305 domain-containing protein"
                     /protein_id="WP_373294652.1"
                     /transl_table=11
                     /translation="MTGTTTTASDVTDTGDTHGHRPALRRWMIAAAAVLLALVLALWLL
                     ATVSSEDGKAANVPTADSADAGFARDMAVHHQQAVEMAYIVRDRTTDEDVRRLAYDIAQ
                     TQANQRGMLLGWLDLWNLPKTSADGYMTWMTDGGHMGHQMKDGSLMPGMAANTELGRLG
                     KLEGKQAEILYLQLMYDHHMGGIDMARACTQQCTVPQERKLAQGMVDGQQSEMKVMADL
                     LRERGSAPR"
     gene            complement(1425..2081)
                     /locus_tag="IEY95_RS41270"
                     /old_locus_tag="GCM10011579_084070"
     CDS             complement(1425..2081)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004979690.1"
                     /locus_tag="IEY95_RS41270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_084070"
                     /product="DUF3105 domain-containing protein"
                     /protein_id="WP_189191384.1"
                     /transl_table=11
                     /translation="MSRTSKKQAAADRKARIEAMRRAERARERRRRIITITVSTVIVAG
                     LVGWGVYAINSANEKQDQKAAAAKAPIRGEEVWDAKKLTRNHVKGQVNYPMNPPVGGDH
                     NPVWMTCDGNVYTKPIAKENAVHSLEHGAVWVTYNTKATKADIKTLADKVSKTPYTLMS
                     PVNDEAGSIMLSAWGHQLSVNTASDPRVEQFLTKYVQGPQTPEPGAACTNGLTAS"
     gene            complement(2182..2601)
                     /locus_tag="IEY95_RS41275"
                     /old_locus_tag="GCM10011579_084080"
     CDS             complement(2182..2601)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY95_RS41275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10011579_084080"
                     /product="hypothetical protein"
                     /protein_id="WP_189191385.1"
                     /transl_table=11
                     /translation="MSRWTQHRPRGARQNTPLTVFCAALTVLFAAVVLCLGPMAHTGVA
                     GTAAAPMATMSTTEQPAQKQTVAVTHQADCPVGDVCCGLAIHAVRAVPVAPAQPLPATL
                     PCIPSLPRPHDTSCSAHSPPTGGAPDLHVLQVQRT"
     gene            complement(2655..4595)
                     /locus_tag="IEY95_RS41280"
                     /old_locus_tag="GCM10011579_084090"
     CDS             complement(2655..4595)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014143466.1"
                     /locus_tag="IEY95_RS41280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_084090"
                     /product="copper resistance CopC/CopD family protein"
                     /protein_id="WP_229703710.1"
                     /transl_table=11
                     /translation="MTALASTLRRPAAALLTVASLVMALLLGTGAPASAHATLLFTSPA
                     ADATVPDSPASLVLVFDQPVGVGSSAVRLAPAAGLGKPTRSQGGRTVTLPVQGKLAEGV
                     HTVNWQVTAQDGDIMTGSYRFAIGPRSVALTSGQSTTAKDPVPTTILRWLLFTALALLL
                     GEAALSRLAARVPDAPSRRPRSWALPAAIVGCAAALGLAALVIGDGSLRSVIDTRPGVL
                     SLIDVAGFSLAALAVGVRRWRAWAVVPLTAVVVAEALRAHPQAEQAVAGPVLTFVHLAA
                     AALWVGALVQVLRTMVAWRGERGASRKLLLAYARLAAWLFAAVVTTGVIAALLLVPLDD
                     VFTTAYGQVLVVKIGVVALVAALAYTARRRLHRTTGRLPYRPARLEASVLAVVLALSAT
                     LTIMRAPADTNRPLAFAPPTTGRVVPAGTRAGEIGVSARASTGQLIIELTAPQVGDTSK
                     QTYGLSATLADPRGTRRALKLRGCGTGCFYTPLTWRKGTSHLTLTASAGEEWAGGRAGL
                     AITWPSRPDTALLRETVAAMKTAPLFSLHELVTSNTARGLGDLKELPITGKEFLAAEPY
                     GSGTAPVTTRLPDENGHRRLALAYPAEHTQLDLTVDEEGRIVHETLTAPNHLVTRTFVY
                     PEPDEEQGHEH"
     misc_feature    4581..4596
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.6"
                     /tool="antismash"
     gene            complement(4746..4967)
                     /locus_tag="IEY95_RS41285"
                     /old_locus_tag="GCM10011579_084100"
     CDS             complement(4746..4967)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY95_RS41285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10011579_084100"
                     /product="hypothetical protein"
                     /protein_id="WP_189191386.1"
                     /transl_table=11
                     /translation="MDKLLYLLPALACPVGMGLMMWLMMRPKHEAQPENGTSASHQELI
                     RLRKEVEALRAEQDAQHTGINPPQDRPA"
     gene            complement(4989..5240)
                     /locus_tag="IEY95_RS41290"
                     /old_locus_tag="GCM10011579_084110"
     CDS             complement(4989..5240)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY95_RS41290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10011579_084110"
                     /product="glutathione S-transferase N-terminal
                     domain-containing protein"
                     /protein_id="WP_189191387.1"
                     /transl_table=11
                     /translation="MITLTLLTQADCTWCERAKKLLAETDEDVEVTEVSLDTDEGRELA
                     ARHRLLFAPGLVHGDRLIAYGRISKRAIRRELDRIPKS"
     gene            complement(5237..5917)
                     /locus_tag="IEY95_RS41295"
                     /old_locus_tag="GCM10011579_084120"
     CDS             complement(5237..5917)
                     /EC_number="1.11.1.24"
                     /GO_function="GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1196: alkyl hydroperoxide reductase/ Thiol specific"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491768.1"
                     /locus_tag="IEY95_RS41295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_084120"
                     /product="peroxiredoxin"
                     /protein_id="WP_189191388.1"
                     /transl_table=11
                     /translation="MSTISKKRPPLWRPDAVIAAEQQANRRRLTLIISSAVAVVALVVL
                     YAVFSTSPAKNTSSSGTSYDVGSPGIGKTAPAFTLAGSTGKQVSLSDYRGKTVLLYFQE
                     GLTCQPCWDQLTALEKSATKVKAAGVDDIVSITTDPADLITRKTEDMSLTTPVLSDPVL
                     KVSKEYGANQYGMMGSSRDGHSFLLVGPDGTVRWRADYGGAPDYTMYVAVDKLLADLKA
                     GVKS"
     gene            complement(5914..6882)
                     /locus_tag="IEY95_RS41300"
                     /old_locus_tag="GCM10011579_084130"
     CDS             complement(5914..6882)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014627987.1"
                     /locus_tag="IEY95_RS41300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_084130"
                     /product="cytochrome c biogenesis CcdA family protein"
                     /protein_id="WP_189191389.1"
                     /transl_table=11
                     /translation="MGDLLFGTTLLASFLGGMVALLAPCCVSVMLPAYLATGFRRRTGI
                     LAATLVFAAGVATVIVPIGLGATALVSLISGHHLLVFSIGGAAMAVGGIALLVGWKPQL
                     PMVGGRAPSGHGFGSVYGLGVFSGAASSCCAPVLAGVAVLSGAAASFPAALAVSLTYVA
                     GMVAPLCLIALIWDRRDWSAGRLLQGRQVTLRLGRLRRRMPLGSAASGILLIAMGALTL
                     VQAVRGPDMASDGWRVRVAADLQHAASLITKALGWLPGWALALILLALAAFLIRQARAH
                     LTAPARRSPDATAGASPTDCCDTSEPQPPVTTVSAGEDRPA"
     misc_feature    6864..6877
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.8"
                     /tool="antismash"
     gene            complement(6975..7952)
                     /locus_tag="IEY95_RS41305"
                     /old_locus_tag="GCM10011579_084140"
     CDS             complement(6975..7952)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014143489.1"
                     /locus_tag="IEY95_RS41305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_084140"
                     /product="M56 family metallopeptidase"
                     /protein_id="WP_189191390.1"
                     /transl_table=11
                     /translation="MIVAAILFTYALLLCTLAPRLLRGAHWTQRAPRLGIVVWQVLGAS
                     ALTAAVLAGLALTVPTVRVSADLAQLLQACVMALTAQYASPGGAAAGAAGAVLALAVLG
                     RTAWCAGTALTRIRRERSEHREILDMVGRPDTTRGVVVLDHEEPAAYCLPGRHRRTVIT
                     TGALRTLDDDQLEAVLAHEHAHQAERHDAVLTWAQTLAHAFPRIPLFRTAEAEIARLVE
                     MRADDVAAARSGRLTTAAALLAVAGGRTPAVALAAGGSTAAQRVHRLIEPRRPLSRMRI
                     AAGSLTAAVALALPLLVVGGPAAAATQLNYCPDGTPSAQVTTTR"
     gene            complement(7949..8320)
                     /locus_tag="IEY95_RS41310"
                     /old_locus_tag="GCM10011579_084150"
     CDS             complement(7949..8320)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014143488.1"
                     /locus_tag="IEY95_RS41310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_084150"
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="WP_189191391.1"
                     /transl_table=11
                     /translation="MTQFGELEAAIMDAVWDAGKSLRVREVLERLDRDPEPAYNTVHTV
                     TEILYRKGWLSKEKDGRAYKYGATKSREEYVAGLMDEALSVAGNRTATLARFVQQMQPG
                     EAEELHRLLGQAVAKEASE"
     gene            complement(8367..9005)
                     /locus_tag="IEY95_RS41315"
                     /old_locus_tag="GCM10011579_084160"
     CDS             complement(8367..9005)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018850293.1"
                     /locus_tag="IEY95_RS41315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_084160"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_189191392.1"
                     /transl_table=11
                     /translation="MAKAVSHPLFARIYPRINAFAEAHGSIEHRREMLAGAHGRVVEIG
                     AGTGANFTHYPPEVEQVVAVEPEPRLRALAEQAATEAAVPVEVWAGRAEELPLDDDSFD
                     VAVYSLVLCTIADVPGALTEAKRVLKPGGELRFYEHVRSERPRFFRMQRLLNPLWGLLG
                     GGCRLTCDTERAIQEAGFTVTEIRRFDFLINGRANPASPSIIGTARLST"
     gene            9122..9889
                     /locus_tag="IEY95_RS41320"
                     /old_locus_tag="GCM10011579_084170"
     CDS             9122..9889
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016325479.1"
                     /locus_tag="IEY95_RS41320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_084170"
                     /product="cytochrome c biogenesis CcdA family protein"
                     /protein_id="WP_189191447.1"
                     /transl_table=11
                     /translation="MSLSAAIPHLVADGPLLLAAPLALLAGAVSFFSPCCLPLVPGYLS
                     YATGMSAADVQAGRESRGRMVAGTALFILGFSVLFASYGAALGYVGNTLLAHQDLITRV
                     LGVLTILLGLLFLGAFERIPFAGRTFRVGYHPRAGLAGAPLLGVMFGLGWTPCIGPTLA
                     AVMSLSFTTGSAGRGALLAFVYSVGLGLPFLIAALGFRRALHAFGFARRNARTVMRSGG
                     AMLVIVGILQVSGLWTYFTGLLRYWVAGFQPAL"
     gene            complement(<10001..10168)
                     /locus_tag="IEY95_RS50895"
                     /pseudo=""
     CDS             complement(<10001..10168)
                     /GO_function="GO:0016755 - aminoacyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR04539.1"
                     /locus_tag="IEY95_RS50895"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="tRNA-dependent cyclodipeptide synthase"
                     /pseudo=""
                     /sec_met_domain="CDPS (E-value: 3.4e-14, bitscore: 46.4,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSDQCHGSAVRMSVTPLSSRCANLMERAERACFGISPFNGYFSP
                     MRIRELAAWGL"
     gene            complement(10241..10912)
                     /locus_tag="IEY95_RS41330"
                     /old_locus_tag="GCM10011579_084180"
     CDS             complement(10241..10912)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240535.1"
                     /locus_tag="IEY95_RS41330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_084180"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_189191393.1"
                     /transl_table=11
                     /translation="MDHEAAPVKQPPSGARAEQKRAAIITAARETFLKEGFSAGIDLIA
                     TNAGVSKVTIYNHFGSKEALFTAVIADALDAPLGGSLVAAIDQLADADDLHKALTDAAQ
                     AWVKGVRDNSDVLAMRNLVTRELHRFPDLGAAWQNQAPGRHHPAVAGALQKLVDKGRLA
                     IPDLEVAIIQLYSLMLYPHLVFSAYGTELDSDLSDRLISHDVEMFLHYYAPTDPAPDGG
                     H"
     gene            11270..12751
                     /locus_tag="IEY95_RS41335"
                     /old_locus_tag="GCM10011579_084200"
     CDS             11270..12751
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015035003.1"
                     /locus_tag="IEY95_RS41335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_084200"
                     /product="MFS transporter"
                     /protein_id="WP_189191394.1"
                     /transl_table=11
                     /translation="MRHVPETAHPDPHGHGTAAPAEHPHRWRLLALLCLAQFMLIADVT
                     VINVALPTIGEDLGLDGSGLTWVVTAYTLFFGSLLLLGGRLADALGKLRAFLAGLTVFT
                     AASIASGLAVGGGMLIAARSAQGVGAALMSPAAMALVTALFHGPDRNKALGVWAAIGGA
                     GSAVGVLLGGVFVSGPGWEWVFFINVPVGLVALFAVPALLGNSPELVRRSGAGGSVDLA
                     GALTLTAAPGLLVYGLVQTRDHGFDTPGFWLPVIGALLSAVVFVAVERRVREPLVRLAL
                     FTRRSLVGGSTVMLAASGLLISSFFLSSFYVQHILGFSALKTGLVFLPVAVAITLGAHA
                     ASHLVDRLGWRPAGAIAFALTAVGAALLTRLDASSDVWTDLVPGFTLLSLALGTAFVCA
                     TTAAMNGLPHQDMGLASGLVSTSHELGAALGVAVISTIAGASLEGGGPGAAAGTSGFDH
                     AFTACAIIAAVVAAVGALLLPAGRPDPAQGPVMPH"
     gene            complement(12837..13463)
                     /locus_tag="IEY95_RS41340"
                     /old_locus_tag="GCM10011579_084210"
     CDS             complement(12837..13463)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004991767.1"
                     /locus_tag="IEY95_RS41340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_084210"
                     /product="TSUP family transporter"
                     /protein_id="WP_189191395.1"
                     /transl_table=11
                     /translation="MTVRGHRGALLRYRREGLLNSPLTRRLVVGTLPGVVIGAVVRVFA
                     VPGANVFRLLVAVLLTPLGLWLVIRTIRPARATPAAEPSPRTITGLALLVGIVGGVYGI
                     GGGSILGPVLVGQGMPVTQVARAALASTFATSVAGAASFALLSLTGSGDIAPDWYLGFA
                     CGLGGLIGGYLGAHLQPRLPETALRLLLGALAAALGVFYAVQSLR"
     gene            complement(13531..15813)
                     /locus_tag="IEY95_RS41345"
                     /old_locus_tag="GCM10011579_084220"
     CDS             complement(13531..15813)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1037: heavy metal
                     translocating P-type ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491841.1"
                     /locus_tag="IEY95_RS41345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_084220"
                     /product="cation-translocating P-type ATPase"
                     /protein_id="WP_189191396.1"
                     /transl_table=11
                     /translation="MTSTAPEKAVPEARPAPAHEVELSIGGMTCASCAARIEKKLNRLD
                     GVTATVNFATEKAKVAYPDGTEVADLIATVEKTGYIAEEPPPPVTAAATEGEAQTAPAA
                     DGELLSLRQRLYISLVLTVPVVLMAMVPSLQFDNWQWLSLTLAAPVVVWGAFPFHKAAW
                     TNARHGAATMDTLVSIGTLAALGWSVWALFWGDAGMPGMRHGFEFTISRGAGSSSIYLE
                     AAAGVTTFILAGRYLEAKSKRKAGAALRALLELGAKDVFVLRGGKEVRIPVAQLAVGDR
                     FVVRPGEKVATDGTVVEGASAVDASMLTGESVPVDVTVGDSVTGATVNAGGRLVVEAAR
                     VGSDTQLARMAKLVEDAQNGKAEVQRLADRISGIFVPVVLLIAAGTFGVWLGVTGDSVA
                     AFTAAVAVLIIACPCALGLATPTALMVGTGRGAQLGILIKGPEVLESTRRVDTVVLDKT
                     GTVTTGRMQLQDVFTAPGVDENELLRLAGALEHASEHPIAQAIAAGAIQRAGSLPVPEN
                     FENVAGLGVQGVVDGHAVLVGREKLLAEWVIDLPQELAEAKAAAEAEGRTAVAVAWNGE
                     ARGVLTVADAVKETSAEAVAELRRLGLKPVLLTGDNQLVAESVAKTVGIDEVIAEVLPQ
                     DKVDVVKRLQGDGRTVAMVGDGVNDAAALATADLGLAMGTGTDAAIEAADLTLVRGDLR
                     VAADAIRLSRRTLATIKGNLFWAFGYNVAALPLAAFGMLNPMIAGAAMAFSSVFVVTNS
                     LRLRRFR"
     gene            complement(15924..16217)
                     /locus_tag="IEY95_RS41350"
                     /old_locus_tag="GCM10011579_084230"
     CDS             complement(15924..16217)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491840.1"
                     /locus_tag="IEY95_RS41350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_084230"
                     /product="heavy-metal-associated domain-containing protein"
                     /protein_id="WP_189191397.1"
                     /transl_table=11
                     /translation="MTTETNSGSCCGTGSCGSGATADVQGVGVTTVYKVSGMTCGHCEG
                     AVSQEISALDGVTAVKAVATTGEVTVISAAPLDEEAVRAAVDEAGYELVGQA"
     misc_feature    16300..16315
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 23.11"
                     /tool="antismash"
     misc_feature    complement(16300..16316)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: medium, score: 28.54"
                     /tool="antismash"
     misc_feature    complement(16301..16316)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: strong, score: 32.38"
                     /tool="antismash"
     misc_feature    complement(16327..16342)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.03"
                     /tool="antismash"
     misc_feature    16470..16485
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.86"
                     /tool="antismash"
     gene            complement(16482..17351)
                     /locus_tag="IEY95_RS41355"
                     /old_locus_tag="GCM10011579_084240"
     CDS             complement(16482..17351)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491838.1"
                     /locus_tag="IEY95_RS41355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_084240"
                     /product="DUF5134 domain-containing protein"
                     /protein_id="WP_189191398.1"
                     /transl_table=11
                     /translation="MGTMALSWAVAVVAALVAAVSAVRVVTTGGEIRFAAGGDLLMGVC
                     MAAMALPATVGWYAGYGMWWALVFGLLGLGGVVMAVKRTRECGWEQGRHWVHLIVGSAS
                     MVIMTLAMTSTSSGPVLALSGSSMARMPGMKHMASMPGAGHAADMESMHGMGSMSGMDM
                     PGMGKAAADTSASAGPVTGWRFVIAGLAAYFLLSIGASVWARVRGTGQGRRGVGSRFSW
                     GRWLLAMLDTVLVFLTSLTLAVWDRARTAQRPGHGRRRKLGAAPDAALAAHIGMGGTMS
                     AMLLMMAA"
     misc_feature    17421..17436
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.81"
                     /tool="antismash"
     gene            complement(17443..18657)
                     /locus_tag="IEY95_RS41360"
                     /old_locus_tag="GCM10011579_084250"
     CDS             complement(17443..18657)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016325455.1"
                     /locus_tag="IEY95_RS41360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_084250"
                     /product="Ig-like domain-containing protein"
                     /protein_id="WP_189191399.1"
                     /transl_table=11
                     /translation="MRQRLTSRLGRRIAQPLAFASAAVVVLAACSTGGKADGDSGKAGG
                     DGDNGAPAAIVVEPGDAKAKVPVSRKVTVRAQGGSLSSVEVSSPGPGALAGTWSKGKSL
                     WTSTTPLAPGAIYTVTATGEASGGSALNKTASFTTEAATNTFVGEYYPDKGAKVGVAMP
                     VSITFNKPIPDKAAIERKLKVAASPAVEGAWSWMKDRNGKDRIDYRPEKYWKPGTNVTL
                     RMDLAGVNAGGGVYGTQQRVVNFTIGDAVTSTVDVKKKTMTVAKNGKTLRTLKVSTGKK
                     GFETWNGTMVVLSKVPTIRMNSDTVGIFGPEAYDLGSVKWDVQLTPSGTYAHAAPWNEG
                     KFGVINGSHGCIGMSTADAKWFYQQVHLGDPVTVVNSVDTVAVNNGYGDWNVDWESWKK
                     ASALH"
     misc_feature    complement(18814..18829)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 23.18"
                     /tool="antismash"
     gene            complement(18909..19199)
                     /locus_tag="IEY95_RS41365"
                     /old_locus_tag="GCM10011579_084270"
     CDS             complement(18909..19199)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015898.5"
                     /locus_tag="IEY95_RS41365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_084270"
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="WP_229703711.1"
                     /transl_table=11
                     /translation="MTVRQVLGVLNADRAQPLACTTVMTVMSRLAEEGVLDRAPQGRGY
                     AYTSAVPDEAALTVREVLCMHGGAAVVHFAIEAALDPGHRDQLWRLLEESL"
     gene            19444..20079
                     /locus_tag="IEY95_RS41370"
                     /old_locus_tag="GCM10011579_084280"
     CDS             19444..20079
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (50-152). E-value: 8.1e-08. Score:
                     22.6. Matches aSDomain: nrpspksdomains_IEY95_RS41370_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491800.1"
                     /locus_tag="IEY95_RS41370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_084280"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_189191401.1"
                     /transl_table=11
                     /translation="MAGSLRHPHPHHHPDSAGPSAPDDLYASPPPWDIGRPQPAFLALA
                     EAGAIQGRVLDAGCGTGEHVLMCAGLGLDATGVDLASRALRNAEGKAREQGRTARFLHW
                     DALKLADLRETFDTVLDCGLFHIFGGADRATYVDNLRAVIRPGGRYLMLCFSDRQPGEW
                     GRVHKLARDEIEASFTEGWRVDSVAPSTIDITTDPGGIRAWLVALTRV"
     aSDomain        19594..19899
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEY95_RS41370_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="8.10E-08"
                     /label="IEY95_RS41370_oMT.1"
                     /locus_tag="IEY95_RS41370"
                     /protein_end="152"
                     /protein_start="50"
                     /score="22.6"
                     /tool="antismash"
                     /translation="QGRVLDAGCGTGEHVLMCAGLGLDATGVDLASRALRNAEGKAREQ
                     GRTARFLHWDALKLADLRETFDTVLDCGLFHIFGGADRATYVDNLRAVIRPGGRYLM"
ORIGIN
        1 ccctgctgat gggctggcag ttcaccgctg cgcgggcgtc ggcggcttag ccgcccgtca
       61 cccgggcggg cagacgggcg agcgcttcgg tgcgggaacc ggtcacggcg tcagcgtgcc
      121 cctcgtcaac agcggcatcg ccgatgacgc attctggagg tagggcacgt ttgcccgcca
      181 gccgaagaag gtgatcggca tgatgtggta cgacggcggc tggggctggg gcggctggtt
      241 cgccatggcc atcttcccgg tgctgttctt ggtgctgctg atcgccggtg tcgtcatgct
      301 cgtccgttac gtcacgggca gccggcacag ccaccagggc ggcccacccc cctctcccgg
      361 tgagcccggg tggggaagca agcgagctga ggacctgctc gccgagcggt tcgcccgcgg
      421 agagatcgac gaggacgagt acaaacgccg gctgacgctg ctgcgggagc accagtgacc
      481 gcgagccgtc cgcgcgcggt gtgtgccgcc ccggaggatg gccctatcgg tctccgatga
      541 gcggcggccc tcgtcagcga ccgcccgagc cgcacgctgt gctcgcgggt cgcccgcgcc
      601 cgcacctcgc tgatcgcgtg gatgaacgag gccgagcact ccgcgccggt ggccgcagcc
      661 gccctgacgg cacgtacggc gacgggcccg gagcgccaag cgatccgggc cctcagtggc
      721 cggcggcgta cgtcatcgcg gtgccgagcc acgctcccgg agcagatcgg ccatgacctt
      781 catctccgac tgctggccgt cgaccatgcc ctgggccagc ttccgttcct gaggcaccgt
      841 gcactgctgg gtacaggcgc gggccatgtc gatgcctccc atgtggtggt cgtacatgag
      901 ctggaggtag aggatctctg cctgttttcc ctcgagcttg ccgagccggc ccagctccgt
      961 gttggcggcc atgccgggca tgagcgagcc gtccttcatc tggtggccca tgtgcccgcc
     1021 atccgtcatc caggtcatgt agccgtcggc ggatgtcttg ggaaggttcc acaggtcgag
     1081 ccagccgagc agcatgccgc gctggttggc ctgggtctgg gctatgtcgt acgcgaggcg
     1141 gcggacatcc tcgtcagtgg ttcggtcccg gacgatgtag gccatctcca cagcctgttg
     1201 atggtggacg gccatgtcgc gagcgaagcc cgcatcggcg gaatccgcgg tgggcacgtt
     1261 ggctgccttg ccgtcctcgc tgctgacggt ggccagaagc cagagcgcca ggacgagggc
     1321 gagcagtacc gccgcagcgg cgatcatcca gcgcctgagc gccggacggt ggccgtgggt
     1381 gtcgccggtg tccgtcacat ctgatgctgt ggtggtcgtg ccggtcatga ggccgtcagg
     1441 ccgttcgtgc aggctgcgcc cggctcgggg gtctgcgggc cctggacgta cttggtgagg
     1501 aactgctcga ccctgggatc ggaggcggtg ttcacgctga gctggtggcc ccaggcgctc
     1561 aacatgatgc ttccggcttc gtcgttgacc gggctcatca gggtgtaggg cgtcttggag
     1621 accttgtcgg cgagggtctt gatgtcggcc ttggtggcct tggtgttgta ggtgacccag
     1681 accgcgccgt gttcgaggga gtggacggcg ttttccttcg cgatgggctt ggtgtagacg
     1741 ttgccgtcgc aggtcatcca caccgggttg tggtcgccgc cgacgggcgg gttcatcggg
     1801 tagttgacct ggcccttgac gtggttgcgg gtcagcttct tggcgtccca gacctcctcg
     1861 ccgcgtatgg gcgccttggc cgcggcggcc ttctggtcct gcttctcgtt ggcactgttg
     1921 atggcgtaca cgccccagcc gaccagtccg gccacgatga ccgtgctgac ggtgatggtg
     1981 atgatccgcc tgcggcgctc gcgggcccgc tcggcgcggc gcatcgcctc gatgcgtgcc
     2041 ttgcggtcgg ctgcggcctg cttcttgctg gtcctgctca tggatacgtc cttgtcccgc
     2101 cgcgaaggtg tggtcgggcg gcggtgggtg cggagatgaa tggagggatg tccgttgtgc
     2161 gcgcatgcac gggcatccgt cctacgttcg ttgcacctgc aggacgtgga gatctggagc
     2221 gccgccggtg ggcggcgagt gggcggagca cgaggtgtcg tgcggccgcg ggaggctcgg
     2281 tatgcaaggc agggtcgcgg gcagcggctg ggcgggcgcg accggtacgg cccgtacggc
     2341 gtggatggcc aagccgcagc acacgtcgcc gacagggcag tcggcctggt gcgtgactgc
     2401 cacggtctgc ttctgggccg gctgctcggt ggtggacatg gtggccatgg gcgccgcggc
     2461 ggtcccggcg acgccggtgt gcgccatggg gcccaggcac agcacaactg ccgcgaacag
     2521 cacggtcagg gcagcacaga agaccgtgag cggcgtgttc tgccgcgcgc cacggggtct
     2581 gtgctgcgtc cagcggctca tggtgatgat gctaagcggt gcttgtgaac attctttcgg
     2641 tcgggcctag gaggtcagtg ctcatgaccc tgctcctcgt ccggctcggg gtagacgaag
     2701 gtgcgggtga ccaggtggtt gggggcggtc agggtctcgt gcacaatccg cccctcctcg
     2761 tcgacggtga ggtcgagctg ggtgtgttca gccgggtagg cgagggcgag gcggcggtgg
     2821 ccgttctcgt cgggcagccg cgtggtgacc ggcgcagtgc cactgccata cggctcggca
     2881 gccaggaact ccttgcccgt gatgggcagt tccttgaggt cgccgaggcc gcgcgcggtg
     2941 ttgctggtga ccagctcgtg caggctgaag aggggcgccg tcttcatcgc ggccacggtc
     3001 tcgcgcagca gcgccgtgtc gggccgggac ggccaggtaa tggcgaggcc tgcgcggccg
     3061 cccgcccatt cctcgcccgc cgaggcggtc agggtgaggt ggctggtgcc cttgcgccag
     3121 gtcagcgggg tgtagaagca gccggtgccg cagccgcgga gcttcagggc tcggcgcgtg
     3181 ccacgcgggt cggcgagggt ggcggacagg ccgtacgtct gcttcgaggt gtcgccgacc
     3241 tggggtgccg tcagctcgat gatgagctgg ccggtactgg cacgggcgct gacgccgatc
     3301 tccccggcgc gggtgccggc gggcacgacc cggccggtgg tcggaggtgc gaaggccagc
     3361 ggacggttgg tgtccgcggg cgcgcgcatg atggtgagcg tggcggacag ggcgaggacc
     3421 acggccagca cggaggcttc gagacgcgcc gggcggtacg ggagcctgcc ggtcgtacgg
     3481 tgcaggcgac ggcgtgctgt gtaggcgaga gcggcgacca gcgcgaccac gccgatcttg
     3541 acgacgagga cctggccgta cgcggtggtg aagacgtcgt ccagtgggac cagcagcagg
     3601 gcggcgatga cgccggtggt gacgacggcc gcgaacagcc atgcggcgag ccgggcgtac
     3661 gcgagcagca gcttgcggga ggcgccacgc tcgccccgcc aggccaccat cgtgcgcaac
     3721 acctgcacca gcgcgcccac ccacagcgcg gcggccgcga gatggacgaa ggtcagcacc
     3781 ggtccggcga cagcctgttc cgcctgcggg tgcgcgcgca acgcctccgc gaccaccacg
     3841 gcggtcagcg ggacgacagc ccaggcccgc cagcgacgta ctccaacggc cagggccgcc
     3901 agggagaagc cggccacgtc gatcagcgaa agcacgccgg ggcgggtgtc gatcacggac
     3961 cgcagtgagc cgtcgccgat caccagcgca gccaggccga gcgccgccgc gcacccgacg
     4021 atagcggcgg gcagcgccca ggagcgcggc cgtcgcgacg gggcgtcggg gacacgggcg
     4081 gcgagtcggc tgagcgcggc ctcgccgagg agcagggcca gggcggtgaa cagcagccag
     4141 cgcagaatcg tggtggggac gggatccttg gcggtggtgc tctggccgga ggtgagggcg
     4201 acggagcgcg ggccgatggc gaagcggtag ctgccggtca tgatgtcgcc gtcttgggcg
     4261 gtgacctgcc agttcacggt gtgcacgccc tcggcgagct tgccctgcac aggaagggtg
     4321 accgtccgtc cgccctggct tcgtgtcggc ttgccgagcc cggctgcggg cgcgaggcgt
     4381 acggcggagc tgccgacgcc gaccggctgg tcgaagacga ggaccagcga ggccggggaa
     4441 tccgggaccg tggcgtccgc ggccgggctg gtgaacagca gcgtggcgtg cgcggaggcg
     4501 ggggcaccgg tgcccagcag gagggccatg acgagcgatg ccacggtgag gagcgcggcg
     4561 gcggggcgcc ggagggtgga tgcgagggcg gtcacaggtc gaggatctcc ggtcggtctg
     4621 gttgtacggc aggcggggtg gcctgcaggt gctgacgttc atcgcggaca cgccccggct
     4681 ccaccgcggg cgcgggacgg aaacggcggt atgcgcggtc gttgtgagct ggagccgtat
     4741 gtcggtcagg ccgggcggtc ctgtgggggg ttgattccgg tgtgctgggc gtcctgctcg
     4801 gcgcgcaggg cttccacttc cttgcgcagc cggatcagct cctggtggct tgcggaggtt
     4861 ccgttctcgg gctgtgcctc gtgcttgggg cgcatcatga gccacatcat caggcccatg
     4921 ccgaccgggc aggcgagggc ggggagcagg tagagcagct tgtccatgac ggggactcct
     4981 tcggtgggtc agcttttggg gatgcgatcg agttcgcggc gtatggcgcg cttggagatc
     5041 cgcccgtacg cgatgagccg gtcgccgtgg acgaggcccg gggcgaacaa caggcggtga
     5101 cgggcggcca gttcacggcc ttcatcggtg tcgagggaca cctcggtgac ctcgacgtcc
     5161 tcatcggtct cggccaggag cttcttcgcc cgctcgcacc aggtgcagtc ggcctgggtg
     5221 agcagggtca gcgtgatcac gacttcactc cggccttgag gtcggcgaga agcttgtcga
     5281 cggcgacgta catcgtgtag tcgggggcgc cgccgtagtc tgcgcgccag cggacggtgc
     5341 cgtccgggcc gaccagcagg aagctgtgcc cgtcacgcga gctgcccatc attccgtatt
     5401 ggttggcccc gtactccttg gagaccttca ggaccgggtc ggacagcacc ggggtggtca
     5461 ggctcatgtc ctcggtcttg cgggtgatca ggtcagccgg gtcagtggtg atcgacacga
     5521 tgtcgtcgac gccggcggcc ttgaccttgg tcgcggactt ctccagagcg gtgagctggt
     5581 cccagcaggg ctggcaggtc aggccctcct ggaagtagag caggacggtc ttgccgcggt
     5641 agtcgctgag gctgacctgc ttgccggtcg agccggcgag ggtgaaggcg ggggccgtct
     5701 taccgatgcc ggggctgccg acgtcgtacg acgtcccgct gctggaggtg ttcttggcgg
     5761 gcgaggtgga gaagaccgcg tacagcacga ccagcgccac cacggcgacc gccgagctga
     5821 tgatcaacgt caggcggcgc cggttggcct gctgctcggc ggcgatcacg gcgtcgggac
     5881 gccacagcgg tggcctcttc ttgctgatgg tgctcatgcg gggcggtcct ctccggcgga
     5941 gacggtggtg acgggtggtt gcggctcgga tgtgtcgcag cagtcggtgg gggaagcccc
     6001 cgccgtggcg tcgggggaac gccgggcggg ggcggtcagg tgggcgcgcg cctgccggat
     6061 caggaaggcg gcgagcgcca gcaggatgag ggcaagcgcc cagccgggca gccagccaag
     6121 ggccttggtg atcagggacg cggcgtgctg caggtcggcg gcgacgcgga cacgccagcc
     6181 gtccgaggcc atgtcggggc cgcgtacggc ctggacgagg gtgagcgcgc ccatggcgat
     6241 gagcaggatt ccggaggcgg cactgcccag cggcatccgt cgccgcaacc ggccgaggcg
     6301 cagggtgact tggcggccct ggaggagacg gccggcgctc cagtcgcggc ggtcccagat
     6361 cagggctatc aggcacagcg gagcgaccat cccggctacg tacgtcagtg agacggcgag
     6421 ggcggcaggg aaggaggcgg cggcgccgga gagaacggcg accccggcta gcaccggggc
     6481 gcagcaggag cttgccgcgc cggagaacac gccgagcccg tagaccgagc cgaagccgtg
     6541 tccggacggg gcgcggcccc cgaccatcgg cagctgcggc ttccagccga ccagcagcgc
     6601 gatcccgccc accgccatcg ccgcaccacc gatcgagaag accagcaggt gatggccgga
     6661 gatcagcgag acgagggcag tggcgccgag cccgatcggc acgatcaccg tggccacccc
     6721 ggcagcgaag accagcgtgg cggccagaat cccggtgcgg cggcggaagc cggtcgcgag
     6781 gtacgcgggc agcatcacgg agacgcagca gggtgcgagc agcgccacca ttccgccgag
     6841 gaacgacgcc agcagcgtcg tgccgaacag aagatctccc atgcggacga cgcctttccc
     6901 ttacctgaaa cctgaactcc taaggagatt aggtcaaagg tggtggcggc gtccagtggc
     6961 gcgcagggag atggtcagcg cgtggtggtg acctgggcgg agggcgtgcc gtcagggcag
     7021 tagttcaact gcgtcgcggc cgctgcggga ccgccgacga ccagcagcgg cagggcgagc
     7081 gcgacagcag cggtcagaga accggcggcg atccgcatgc ggctgagcgg ccggcgcggc
     7141 tcgatgaggc ggtgtacgcg ctgcgcggcg gtggagcctc ccgccgccag tgccaccgcc
     7201 ggggtgcgtc cgcctgcgac cgcgagcaga gcggcggctg tggtcagccg tccggagcgg
     7261 gcggcggcta cgtcgtcggc acgcatctcc accaagcgcg cgatctccgc ctcggcggta
     7321 cggaacaggg ggatgcgggg gaaggcgtgg gcgagtgtct gcgcccaggt caggaccgcg
     7381 tcgtgccgct cggcctggtg ggcatgctcg tgggcgagga ccgcttcaag ctggtcgtcg
     7441 tcgagggtac gcagggcacc ggtggtgatc accgtgcggc ggtggcggcc gggcaggcag
     7501 taggcggcgg gttcctcgtg gtcgaggacg accacgccac gggtcgtgtc cggccgcccg
     7561 accatgtcga ggatctcgcg gtgctcgctg cgctcgcggc ggatccgcgt cagagcggta
     7621 cccgcacacc aggccgtacg ccccagcacc gccagggcga gcaccgctcc ggccgcgccc
     7681 gctgctgcgc cacccggcga ggcgtactgc gcggtcagcg ccatcacgca cgcctgcagc
     7741 aactgtgcga ggtcggcgct gacacgaacc gtgggcacgg tcagggcaag gccggccaga
     7801 acggcggcgg tgagcgccga ggcgcccagc acctgccaga ccacgatgcc gagtcggggt
     7861 gcgcgctggg tccagtgcgc tccgcgcagc agccgcggcg caagggtgca cagcagcagt
     7921 gcgtacgtga acaggatggc ggcgacgatc actcggacgc ctccttggcc acggcctgtc
     7981 cgagcagccg gtgcagttcc tcggcctcgc cgggctgcat ctgctgtacg aagcgggcga
     8041 gcgtcgcggt gcggttcccg gccacggaca gggcctcgtc catcagtccg gcgacgtact
     8101 cctcgcggct cttggtggcg ccgtacttgt aggcgcggcc gtccttctcc ttcgacagcc
     8161 agcccttgcg gtagaggatc tcggtgacgg tgtgcacggt gttgtacgcg ggctccgggt
     8221 cacggtcgag acgctcgagg acctcgcgga cgcgcagcga cttgcccgcg tcccacaccg
     8281 cgtccatgat cgcggcctcc agctcaccga actgcgtcat gcgccctcct cccggaccgg
     8341 aatgcccttc agacatccta agcggcctag gtggacagcc gggcggttcc gatgatcgac
     8401 ggggaggcgg ggttggcccg gccgttgatc aggaagtcga agcggcggat ctccgtcacc
     8461 gtgaagcccg cctcctggat ggcccgttca gtgtcgcagg tgaggcgaca gccgccgccg
     8521 agcaagcccc acagtgggtt cagcagtcgc tgcatccgga agaaacgggg gcgctcggac
     8581 cgtacgtgct cgtagaagcg cagctctccg cccggcttga ggacccgctt ggcctcggtg
     8641 agcgcgcccg gcacatcggc gatggtgcac agcacgagcg agtacaccgc cacgtcgaag
     8701 ctgtcgtcgt ccaggggcaa ctcttcggcg cggcccgccc agacctccac cggcaccgcg
     8761 gcctccgtgg ccgcctgctc ggcgagtgcg cgcagcctgg gctccggctc cacggcgacg
     8821 acctgctcaa cttcgggcgg gtagtgggtg aagttcgcgc cggttccggc gccgatctcg
     8881 accacccggc cgtgcgcgcc cgcgagcatc tctcggcggt gctcgatcga gccgtgcgcc
     8941 tcggcgaagg cgttgatgcg cgggtagatc cgggcgaaca gcgggtgcga cacggctttg
     9001 gccatgacgt cctcctcaga ggcggagaag ggggacctct ccacttcacc taatcaggtt
     9061 aggagtattg tcgcgggggc gtccaggccg gcgcaccgtt ccctcgtgcc cgttctggag
     9121 gctgtccttg agtgccgcca taccccacct cgtcgccgac gggccgctgc tgctggccgc
     9181 gccactcgcg ctgctggccg gcgcggtgtc gttcttctcg ccctgctgcc tgccgctggt
     9241 gcccggctac ctctcgtacg ccaccggcat gtcggccgcc gacgtgcagg cgggtcggga
     9301 gagccggggc cggatggtcg ccgggacggc gctcttcatc ctcggcttct ccgtcctctt
     9361 cgcgagctac ggcgcggcac tcggctatgt cggcaacacc ctgctcgccc accaggacct
     9421 catcacccgc gtcctcggcg tgttgaccat cctgctcggc ctgctcttcc tcggcgcctt
     9481 cgagcggatc ccgttcgccg gacgcacctt ccgcgtcggc taccacccac gcgcgggcct
     9541 ggccggagcc ccgctgctcg gggtgatgtt cgggctgggc tggaccccct gcatcggccc
     9601 cacactcgcc gccgtaatga gcctgtcctt caccaccggc agcgccggac ggggcgccct
     9661 gctcgccttc gtctacagcg tcggcctggg cctgcccttc ctcatcgccg ccctcggctt
     9721 ccgccgcgcc ctgcacgcat tcgggttcgc ccgccgcaac gcccggacgg tcatgcggtc
     9781 cggcggcgcg atgctggtga tcgtcggcat tctgcaggtc agcggcctgt ggacgtactt
     9841 caccggactg ctgcgctact gggtggccgg cttccaaccg gcgctgtgaa caccacgaaa
     9901 gcggggctgg agcgccagtg cgggctagca tcccgtgcca tggccaggac acctgtgcag
     9961 ttgcccgcgg cccggcggtg ggccgggctg cgaaccaggc cagtccccac gccgccagtt
    10021 cccggatccg catcggggag aagtagccgt tgaacgggct gatcccgaag cacgcgcgct
    10081 cagccctctc catcaggttc gcgcagcgac tgctcaacgg agtcaccgac atccggaccg
    10141 cggagccatg gcactgatct gaactcatgg ccggacgcta tgcccttccc ccaacagcaa
    10201 cagcaagcaa ttacccggcc gactcactcg aagggagtgc tcaatgaccg ccgtccggcg
    10261 cagggtcggt cggggcgtag tagtgcagga acatctccac atcgtgcgag atgagtcggt
    10321 cggacaggtc ggaatcgagt tcggtgccgt acgcgctaaa caccaggtgc ggatagagca
    10381 tcagtgagta gagctggatg atcgccactt ccaggtcggg gatggcgagt cggcccttgt
    10441 ccacgagttt ctgcagcgcg cctgccacgg ccgggtggtg gcgccccggg gcttggttct
    10501 gccaggcggc gccaaggtcg gggaagcggt gcagttcgcg ggtaacgagg ttgcgcatgg
    10561 ccaggacgtc ggagttgtcc cggaccccct tgacccaggc ctgggccgcg tcagtgaggg
    10621 ccttgtgcag gtcgtccgcg tcggcgagct ggtcgatcgc ggcgaccagg gacccgccga
    10681 gcggggcgtc gagcgcgtcc gcgatcacgg cggtgaacag ggcttctttg ctgccgaagt
    10741 ggttgtagat cgtcactttg gacacgcccg cattggtggc gatgaggtcg attcccgccg
    10801 agaaaccctc cttgaggaaa gtctcgcgag cggccgtgat gatcgccgct cgcttctgct
    10861 ccgcgcgcgc tccggacggt ggctgcttga cgggggccgc ctcgtgatcc atggccgcat
    10921 cttagtccaa gtgaactgaa cagttgagtt cagttgatat gaactgtact gttcagttca
    10981 tgaatgcagt tcctgtccgc gcaccggcgg agtccctctt cctgcagtgg cgccgcccct
    11041 gactggccct agccgtgctc agcgtgagcc ctctggtggt ggggctggac accaccgtcc
    11101 tactgcccgg acaggcggga gccgctgtcg cccacacggc ccgtgaggca ttcgctacag
    11161 ggctcggccc ggccaagttc accggagccg cgatcgccgc tgctggcgtc gacaccgctc
    11221 tcactcttgc acctcgccgt atcgaatccg acgactcggg agaccagtca tgcgccacgt
    11281 accggaaacc gcccatcccg atccgcacgg gcacgggaca gctgcccctg ctgaacaccc
    11341 acaccgatgg cgactgttgg ccctgctctg cctcgcccag ttcatgctga tcgcggacgt
    11401 gaccgtcatc aacgtcgccc tgccgactat cggtgaggac ctcggcctcg acggctcggg
    11461 actcacctgg gtcgtcaccg cgtacaccct cttcttcggc agcctgctgc tgctcggcgg
    11521 gcggctcgcg gacgccctcg gcaagctgcg cgccttcctc gccgggttga cggtgttcac
    11581 tgcggcgtcc atagcctccg ggctcgcagt cggtggcgga atgctcatcg ccgcccgctc
    11641 agcccagggc gtcggcgcgg ccctgatgtc accggccgcg atggccctcg ttacggccct
    11701 cttccacgga cccgatcgca acaaggccct cggagtctgg gccgcgatcg gcggcgccgg
    11761 atctgccgtg ggtgtgctgc tcgggggcgt gttcgtctcc gggcccggct gggagtgggt
    11821 gttcttcatc aacgtcccag tgggcctcgt cgctctcttc gcggtcccgg cgcttctcgg
    11881 caactccccc gaacttgtgc gtcgttcggg cgccgggggc tccgtcgatc tagcgggcgc
    11941 tctcaccctc accgccgcgc ccggcctgct ggtctacggg ctggtgcaga cccgcgacca
    12001 cggtttcgac acgccgggtt tctggctgcc ggtgatcggc gccttgctgt cggcggtcgt
    12061 ctttgtcgcg gtcgagcgcc gggtgcgcga acccctcgta aggctcgcgc tcttcacgcg
    12121 ccgctcgctc gtcggcggca gcaccgtcat gctggccgcc tccgggctgc tcatctcgag
    12181 cttcttcctc agctcgttct acgtccaaca catcctcgga ttcagcgcgt tgaagacggg
    12241 gctcgtcttc cttccggtcg ccgtggccat caccctcgga gcgcatgccg cctcccacct
    12301 cgtggatcgg ttgggctggc gccccgccgg tgcgatcgcc ttcgccctga ccgccgtagg
    12361 tgccgcgctg ctcacgcgtc tggacgcgag cagcgacgtc tggaccgacc tcgtccctgg
    12421 cttcacactg ctgtcactcg ccctcggtac cgccttcgtc tgcgccacta ccgcggccat
    12481 gaacggattg ccgcaccagg acatggggct cgcctccggg ctggtgagca catcgcacga
    12541 actcggagcg gcgctcggcg tcgccgtgat ctcgaccatc gccggggcaa gccttgaagg
    12601 tggcggcccg ggggcagcgg ccggaacgag cggcttcgac cacgccttca ccgcgtgcgc
    12661 gatcatcgct gccgtggtcg ccgccgttgg tgcgctgttg ctgccggcgg ggcgcccgga
    12721 tccggcgcag gggccggtca tgccacactg acggcgccgt cgatcttggg ttcgggcatg
    12781 agggtacgca gttcccggag gctggcgctg caaccgccac gtgtggctga gcagcgtcag
    12841 cgcagggact gcacggcgta gaagacgccg agggccgcgg ccagtgcgcc gagcagcagg
    12901 cgcagcgcgg tctccggcaa gcggggctgc aggtgcgcgc cgagatagcc gccgatcagc
    12961 ccaccaagac cgcaggcaaa gccgaggtac cagtcgggag cgatgtcacc ggagccggtg
    13021 agggacagca gcgcgaagga cgcagcgccg gccacggagg tggcgaaggt ggaggccagg
    13081 gcggcccggg caacctgggt gacgggcatg ccctggccga ccaggacggg tccgaggatg
    13141 gagccgccgc cgatcccgta gaccccgccg acgatcccaa cgagcagagc caggcctgta
    13201 atagtgcggg gcgaaggttc cgccgccggt gtggcccggg caggtcggat ggtgcggatg
    13261 acaagccata gaccgagcgg cgtgagcaga acggcgacga ggaggcggaa gacattagcc
    13321 cccgggacag cgaacacccg caccacggcg ccgatgacca caccgggcag ggtgccgacc
    13381 accaggcggc gggtcagcgg gctgttcaac aggccctcgc ggcggtagcg cagcagggcg
    13441 ccccggtggc cgcggactgt catcgccctg agaaccggcg gggcgcccgg ccggtgaccg
    13501 ggcgccccag atcggatgtt gccgctccgg ctacctgaag cgacgcagtc gcaggctgtt
    13561 ggtgacgacg aagactgagg agaaggccat cgcggcgccc gcgatcatcg ggttcagcat
    13621 gccgaaggcg gccagcggca gggccgcgac gttgtagccg aaggcccaga aaaggttgcc
    13681 cttgatggtg gcgagggtcc tgcgggagag ccggatcgcg tcggcggcca cgcgcaggtc
    13741 gccgcgcacg agggtcaggt cggccgcctc gatggccgcg tccgtaccgg tgcccatcgc
    13801 caggcccagg tcggcggtgg cgagggcggc cgcgtcgttg acgccgtcgc cgaccatcgc
    13861 gacggtacga ccatccccct gcagccgctt gacgacatcc accttgtcct ggggcaggac
    13921 ctcggcgatc acctcgtcga tgccgacggt cttggccacg gactcggcga cgagctggtt
    13981 gtcgccggtc agcaggaccg gcttcagacc cagcctacgc agctcggcca ccgcttcggc
    14041 actggtctcc ttgaccgcgt cggcgacggt gaggacgccg cgcgcctcgc cgttccaggc
    14101 gacggcgaca gccgtacgcc cctcggcctc cgctgcggcc ttggcctcgg ccagctcctg
    14161 aggaaggtcg atgacccact ccgccaggag cttctcgcgt ccgacgagga ccgcgtgacc
    14221 gtcgacgacg ccctggacgc cgaggccggc gacgttctcg aagttctccg gcaccggcag
    14281 gcttccggcc cgctggatcg caccggccgc gatggcctgg gcgatggggt gctccgaggc
    14341 gtgctccaac gcgcccgcca gccgcagcag ttcgttctcg tccacaccag gtgcggtgaa
    14401 gacgtcctgg agctgcatcc ggccggtggt gaccgtgccg gtcttgtcca ggacgacggt
    14461 gtcgacgcgg cgcgtggact ccagcacctc ggggcccttg atgaggatgc ccagctgcgc
    14521 cccgcgcccg gtcccgacca tcagggcggt cggcgtggcg agccccagcg cgcacgggca
    14581 ggcgatgatc aggaccgcga cggccgcggt gaacgcggcg accgagtcgc cggtgacacc
    14641 gagccacacc ccgaacgtac cagctgcgat cagcagcacc accggaacaa agatcccgga
    14701 gatccggtcg gcaagccgct gcacttcggc cttgccgttc tgcgcgtcct ccaccagctt
    14761 cgccatgcgc gcgagctgag tgtcggagcc gacccgggcg gcctcgacga cgagccgccc
    14821 accggcgttg acggtggcgc cggtgacgga gtcgcccacg gtcacgtcca ccggcaccga
    14881 ctcaccagtc agcatcgagg cgtccaccgc ggaggcaccc tcgacgacag tgccgtcggt
    14941 cgcgaccttc tccccgggcc gtacgacgaa acggtcaccg acggccaact gcgcgactgg
    15001 gatacgtact tccttgccgc ctcgcagcac gaagacgtcc ttcgctccga gctccagcag
    15061 cgcccgcagc gccgcgcccg ccttgcgctt ggacttcgcc tccaggtagc gcccggcgag
    15121 gatgaacgtc gtcacgccgg ccgcggcctc cagatatatg gaggaggagc cggcgccgcg
    15181 ggaaatggtg aactcgaagc cgtgccgcat gcccggcatc ccggcgtcgc cccagaacag
    15241 ggcccacacc gaccagccga gcgcggcgag cgtgccgatg gacaccaggg tgtccatggt
    15301 cgcggcgccg tgccgggcgt tcgtccaggc ggccttgtgg aaggggaagg cgccccagac
    15361 cacgaccggt gcggccagcg tcagcgacag ccactgccag ttgtcgaact gcagggacgg
    15421 caccatcgcc atcaggacga cgggcaccgt gagcacgagt gatatgtaca gacgctgccg
    15481 cagcgacagc agctcaccat cagccgccgg ggcggtctgt gcttctccct cggtcgcggc
    15541 cgcggtgacg ggcgggggcg gctcttcggc gatgtagccg gtcttctcga cggtggcgat
    15601 gaggtcggcc acctcggtac cgtccgggta cgcgaccttc gccttctcgg tggcgaagtt
    15661 gacggtcgcg gtgacgccgt ccaggcggtt gagcttcttc tcgatgcggg cggcgcacga
    15721 ggcgcaggtc atcccgccga tggagagctc gacctcatgg gcgggcgcgg gtcgcgcctc
    15781 ggggactgcc ttctcgggag ccgtgctggt catgggcgta tctcctgggt aggccaggac
    15841 gtacggcgtc cgtatcagcg gagcggcacg ccccggcgcg gggagggttc tcgcgttgcc
    15901 ggggactgac cccggcggag ctgtcaggcc tggccgacga gctcgtagcc ggcctcgtcg
    15961 acggcggccc ggacggcctc ctcgtcgagc ggggcggcgg atatgacggt cacctcgccg
    16021 gtcgtggcga cggccttgac tgcggtgacg ccgtcgagcg cggagatctc ctgggagacc
    16081 gcgccctcgc agtggccgca ggtcatgccg gagaccttgt agacggtggt gacgccgacg
    16141 ccctggacgt cggccgtggc gccggagccg caggaacctg tgccgcagca ggagccggag
    16201 ttcgtctcag tggtcatggc ttcttcctca gggtgtgaat gcgcgggtcg cccttgaaga
    16261 ggggcatcgt tgccggcccc tcccgaacgc gacaacacta taccccccag gggtattcca
    16321 tcaccctgtg gcaccgttca cacggcaacg gtcgagccaa ggcgccgctc gcgatatcga
    16381 aggcccttcc cccgctccca cggcgaccgc aattccgcct cgccatgaag gcggcgccaa
    16441 accggaccct ggtcaccgcg ccggtcagcg gcacccggcg gtcacgcggc catcatcaac
    16501 agcatcgcgg acatggtccc gcccatgccg atgtgcgccg ccagcgcggc atccggcgcg
    16561 gctccgagtt tgcgccgccg accatggccc ggccgctgcg ccgtcctggc cctgtcccac
    16621 accgcgagcg tcagtgacgt caggaagacg agcaccgtgt ccagcatggc aagcagccag
    16681 cggccccagc tgaaccgcga gccgacaccc cgccgaccct gacccgtgcc acggaccctc
    16741 gcccacacgg acgcgccgat cgacagcaag aagtacgcgg cgagccccgc gatcacgaat
    16801 cgccacccgg tgacgggccc cgcggaggca ctggtgtcgg cggcggcctt ccccatgccc
    16861 ggcatgtcca tcccggacat ggagcccatc ccgtgcatcg actccatgtc agccgcgtga
    16921 cccgcgcccg gcatgctcgc catgtgcttc atgcccggca tacgcgccat ggaggagccg
    16981 ctgagcgcga gcaccggtcc ggacgacgta ctcgtcatgg ccagcgtcat gatcaccatg
    17041 ctggcgctgc cgacgatgag gtgcacccag tgacggccct gttcccaccc gcactcccgc
    17101 gtgcgcttga ccgccatcac cacaccgccg agtccgagca ggccgaatac cagcgcccac
    17161 cacatgccat agcccgcgta ccagccgacc gtcgccggca gggccatggc ggccatacac
    17221 acacccatca gcaggtcacc gcccgccgcg aaccggatct cgccgccggt ggtcaccacc
    17281 cgaaccgcac tcacggcggc caccaaagcg gcgaccaccg ccacggccca actgagcgcc
    17341 atagttccca tgttcaccat cccgatggac cggtaattac tagtgccctt agtacgtccc
    17401 gggatcggaa ggtgttcagg aagcctttgg cgaaccggcg cgtcagtgga gggcgctggc
    17461 cttcttccag ctctcccagt cgacgttcca gtcgccgtag ccgttgttga ccgccacggt
    17521 gtcgacggag ttgaccacgg tgaccgggtc accgaggtgg acctgctggt agaaccactt
    17581 ggcgtccgcc gtgctcatgc cgatgcaccc gtgactgccg ttgatcacgc cgaacttgcc
    17641 ctcgttccag ggcgctgcgt gcgcgtacgt gccggacggg gtgagctgga cgtcccactt
    17701 caccgagcca aggtcgtacg cctcggggcc gaagatgccg acggtgtcgg aattcatgcg
    17761 gatggtcggc accttgctca ggacgaccat cgtgccgttc caggtctcga agcccttctt
    17821 tccggtggag accttcaggg tccgcagggt cttgccattc ttcgcgaccg tcatggtctt
    17881 cttcttgacg tcgacggtgc tggtcacggc gtcgccgatg gtgaagttca cgactcgctg
    17941 ctgggtgccg tacacgccac cgcccgcgtt gacgcccgcg aggtccatgc gcagggtgac
    18001 gttggtgccg ggcttccagt acttctcggg gcggtagtcg atgcggtcct tgccgttgcg
    18061 gtccttcatc cagctccagg cgccctcgac cgcgggggaa gctgcgacct tgagcttgcg
    18121 ctcgatcgcc gccttgtcgg ggatcggctt gttgaacgtg atcgagaccg gcatcgcgac
    18181 gccgaccttc gcgcccttgt cggggtagta ctcgccgacg aaggtgttcg tcgccgcctc
    18241 cgtagtgaac gaggcggtct tgttgagggc cgatccgccg gatgcctcgc ctgtggcagt
    18301 caccgtgtag atggcacccg gggcgagggg tgtcgtggag gtccacaggg acttgccctt
    18361 cgaccaggtg ccggcaagtg cgcccggacc aggtgagctg acctcgacgg acgagagtga
    18421 tccaccctgg gcgcgcaccg tcaccttccg actgaccgga accttggctt tcgcgtcgcc
    18481 gggctccacc actatcgcgg ccggtgcgcc gttgtcgcca tcgccccccg ccttgcccga
    18541 gtcgccgtcc gccttaccac cggtgctgca cgcggcgagg acgacgacgg cagccgaggc
    18601 gaacgcgagc ggctgcgcga tccggcggcc gagccgcgat gtcaggcgct gtcgcatgag
    18661 gctccccctc ccattcccta ttaacctaag taccttagta gacgattagc gagacttccg
    18721 ggttcccctc acgctcgcca ccccgctcgg atcccgagtg cccaggaagg gcaacggcct
    18781 gcccggcgga aggggctgca tcgaacgtcc aggtaccccc taggtgcaag atgccgatct
    18841 ggtcatcacg gcacaggtgg agcgccgtcg tcggcattgc gcgccgcgat ccagcgccgc
    18901 agcgacattc acagcgattc ctccagcaag cgccacagtt ggtcacggtg accgggatcg
    18961 agggcagctt caattgcgaa gtgcacgacg gcggcgcccc cgtgcatgca caggacctcc
    19021 cgtacggtga gggccgcctc gtccggcacg gcagaggtgt acgcgtagcc gcggccctgc
    19081 ggggcacgat cgagcacgcc ctcctccgcg agccgactca tcaccgtcat cacggtcgtg
    19141 cacgccagcg gctgggcacg gtccgcgttc agcacgccca agacctgacg gaccgtcacc
    19201 gaacgttccg cgcccatcac acccgcatgc cctctccctc gagcggcccc agaagcaccg
    19261 ccagcgcccc ttgagcccat tcctactacg cgaacgcagt acgccgagcg tccgtcgcct
    19321 acgcgacgcc aggatcgaga caacatggat tgacatagac agtgtgtctc gataaagctt
    19381 gtggtcgtca ccagcacccg gacaaggaac cggaacaccg gacgcaacgg gaaggacacc
    19441 ggcatggccg gctcactccg ccacccccac ccgcaccacc atcccgattc cgcaggaccg
    19501 tcagcgcccg acgacctgta cgccagccca ccgccctggg acatcggtcg gccacaaccg
    19561 gccttcctcg ccctcgccga agcgggcgcc atccagggcc gggtactgga cgccggctgc
    19621 ggaaccggcg agcacgtgct catgtgcgca ggtctcggcc tggacgccac gggcgtcgac
    19681 cttgcctccc gggccttgcg aaacgccgag gggaaggcgc gcgagcaggg ccgcacggcg
    19741 aggttcctcc actgggacgc cctgaagctg gccgatctcc gggaaacctt cgacaccgtg
    19801 ctcgactgcg ggctcttcca catcttcggc ggcgccgacc gcgccactta cgtcgacaac
    19861 ctccgagccg tgatccggcc gggcggccgc tacctcatgc tgtgcttcag cgaccgacag
    19921 cccggcgagt ggggacgggt gcacaagctc gcacgggacg agattgaggc ctcgttcacc
    19981 gagggatggc gcgtcgactc cgtcgcaccc agcacgatcg acatcaccac cgacccgggc
    20041 ggcatccggg cttggctcgt cgccctcacc agggtctgaa catctcaact ccccccgatc
    20101 gaacgggagg agctcggaaa ggaacaccat gccgatcgcg gaagcccgtg tcgagaccga
    20161 tcgtgcga
//
