LOCUS       NZ_BMMM01000022        25271 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces albiflavescens strain CGMCC 4.7111 sequence22, whole
            genome shotgun sequence.
ACCESSION   NZ_BMMM01000022
VERSION     NZ_BMMM01000022.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces albiflavescens
  ORGANISM  Streptomyces albiflavescens
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 160368)
  AUTHORS   Sun,Q. and Zhou,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 100X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014645835.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 03:24:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,828
            CDSs (total)                      :: 9,745
            Genes (coding)                    :: 9,386
            CDSs (with protein)               :: 9,386
            Genes (RNA)                       :: 83
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 359
            CDSs (without protein)            :: 359
            Pseudo Genes (ambiguous residues) :: 0 of 359
            Pseudo Genes (frameshifted)       :: 102 of 359
            Pseudo Genes (incomplete)         :: 321 of 359
            Pseudo Genes (internal stop)      :: 17 of 359
            Pseudo Genes (multiple problems)  :: 80 of 359
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:54:32
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 35264
            Orig. end                         :: 60535
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMMM01000022.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25271
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /product="melanin"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /rules="melC"
                     /tool="antismash"
     cand_cluster    1..25271
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /detection_rules="melC"
                     /kind="neighbouring"
                     /product="terpene-precursor"
                     /product="melanin"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..21050
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21050
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11050](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11050)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    521..535
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.35"
                     /tool="antismash"
     gene            complement(904..2286)
                     /locus_tag="IEY95_RS40915"
                     /old_locus_tag="GCM10011579_083330"
     CDS             complement(904..2286)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016433187.1"
                     /locus_tag="IEY95_RS40915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_083330"
                     /product="hypothetical protein"
                     /protein_id="WP_189191323.1"
                     /transl_table=11
                     /translation="MRGTAFTETMLGTIRLDAKTRERRIRLDLHAEADGILRPHRTTPA
                     RLTGRVRIAGFADDPRAEGELEVSPLARRRIRYQLAFTADGRRLTLDGWKSVTARRPVE
                     SMTVLPFTLYEGDARVGEGVLRFPLATGLAPFLLSFRFPRRESSAEHFPPRWNGEPGRT
                     EVWYTTLTDPASGTGVWLHHEVTAPADGSEPFAHGWVAAFPREGAVRHARFGPVPWTRP
                     ADGFAGDNVTVVPGELTGNAGDFHWKLTEHPQGEPLFTFPRWSWRRPLLPAAQMLPAAR
                     ATYEGEFSYGEQALTLRGAPGASARIYGHGNAHRWTWLHAELGGGDVLEIVAAVSTRPG
                     LRRLPPLVFLRLRRRGRTWPRRAERTALGWLGMGRFRAVFGLPKWTVTGRTAFRRIRVE
                     VDQPAERTLTLEYRDPDGARAVCRNSESADARIVLERWWGRWRPEATWLLDGTAHAEAG
                     ER"
     gene            complement(2283..2969)
                     /locus_tag="IEY95_RS40920"
                     /old_locus_tag="GCM10011579_083340"
     CDS             complement(2283..2969)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018890896.1"
                     /locus_tag="IEY95_RS40920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_083340"
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="WP_189191324.1"
                     /transl_table=11
                     /translation="MEALPRETIVDVLEDRLRTDILDGRHPAGSYLPPERQLADGYGVT
                     RTTLKHAFGRLVQAGLLETRHGVGTRVRDYARLGGADLLPMLVRHDAKWVHEIFEVRRG
                     VGALIAERAASRATRKQCAQLHVLLEAVREADGADAVQLADVEVHRALARATGNRVYLL
                     LTNTLFNAYLPVRSLLKGPFTDPSAAYERLAPVVAAVTAQDARQAHAAADAYLRATERI
                     MLEGLA"
     misc_feature    complement(3176..3191)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.15"
                     /tool="antismash"
     misc_feature    complement(3187..3201)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 25.66"
                     /tool="antismash"
     misc_feature    3188..3202
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 26.03"
                     /tool="antismash"
     gene            3227..4423
                     /locus_tag="IEY95_RS40925"
                     /old_locus_tag="GCM10011579_083350"
     CDS             3227..4423
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982491.1"
                     /locus_tag="IEY95_RS40925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_083350"
                     /product="glycoside hydrolase family 64 protein"
                     /protein_id="WP_189191325.1"
                     /transl_table=11
                     /translation="MPRKIRWRALAVAVATLATALVTFGTPSRAEAAVPATIPLKFTNN
                     SGRSDPVYIYDLGTQLSTGRQGWADANGTFHAWPAGGNPPTPAPDASIVGPANGQSKTI
                     RIPKFSGRIYFSYGQKLDFRLTTGGLVQPAVQNPSDPNRNILFNWSEYTLNDSGLWINS
                     TQVDMFSAPYAVGVQLADGTTKNTGHLKAGGYNGFFNALRGQPGGWANLIQTRSDGTVL
                     RALAPGHGIEAGALPSTVMDNYVNRVWQKYSSSTLTVTPFADQPNTKYFGRVSGDVMNF
                     TNSAGAVVTSFQKPDSDSIFGCYKRLDAPNDLVRGPISRTLCAGFNRSTLLVNPHQPDT
                     SSANFYQDTVTNQYARKIHAQMADGKAYAFAFDDVGNYESLVHDGNPQQAYVTLDPFN"
     misc_feature    3254..3256
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4460..5587)
                     /locus_tag="IEY95_RS40930"
                     /old_locus_tag="GCM10011579_083360"
     CDS             complement(4460..5587)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007501047.1"
                     /locus_tag="IEY95_RS40930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_083360"
                     /product="sulfite oxidase"
                     /protein_id="WP_189191326.1"
                     /transl_table=11
                     /translation="MGHRLDEVSAPARLAEPEEGISQEELALAARNHGMPLEALRYDVT
                     PPGLHYVLTHYDIPYVPEGAWELVVGGGVRRPLVLGMDELRAYPAVTRRVTLECAGNGR
                     ALLTPRPVSQPWLVEAVGTAEWTGVPLRVLLTEAGVEPGAVDVVFTGADHGVERGVEQD
                     YQRALALDVAMGGEPEVLVAYEMNGGPLPPQHGHPVRLVVPGWYGMAHVKWLREIRVTD
                     TSFTGFQQAVAYRLRRDAGDEGEPVTRIAPRALLIPPGFPDFMSRTRVVRPGAVTLEGR
                     AWSGRAPVTGVEVSTDAERSWCAADLDGGDEHRWAWRPWRFAWTATPGPHVLSARAVDA
                     EGHTQPLDQPWNRGGFANNLVQRVPVLCLDSEGAG"
     gene            complement(5629..6276)
                     /locus_tag="IEY95_RS40935"
                     /old_locus_tag="GCM10011579_083370"
     CDS             complement(5629..6276)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387335.1"
                     /locus_tag="IEY95_RS40935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_083370"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_189191327.1"
                     /transl_table=11
                     /translation="MSTPLPRFPKRQEPSDEPVLMELTAPSEAPQLRADAARNRARLLE
                     AAAHLVEEHGVAKLTMDAVAAAASVGKGTVFRRFGDRTGLLMALLDHTEQRFQTDFISG
                     PPPLGPGASPVERLHAFGCRALRQASEQLDLYLAAEPEASRRFGSAPYRVRFMHVCMLL
                     RQADPTTDIELVAQTLMGYLEPALLHHLTRQRGMSIERLEAGWHDLVERSTR"
     gene            6393..6956
                     /locus_tag="IEY95_RS40940"
                     /old_locus_tag="GCM10011579_083380"
     CDS             6393..6956
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009191782.1"
                     /locus_tag="IEY95_RS40940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_083380"
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="WP_189191328.1"
                     /transl_table=11
                     /translation="MSVRILALVGSLRAGSHNRQLAEAAVKLAPEGAEVELYEGLAEVP
                     FYNEDIDVEGSVPATAARLREAAGRADAFLLFSPEYNGTIPAVLKNAIDWLSRPYGAGA
                     FIGKPVAVVGTAFGQFGGVWAQDEARKAVGIAGGTVLEDVKLSIPGSVTRFAETHPVDD
                     AEVAGQLTEVVSRLHSQVGAADAA"
     gene            7094..7771
                     /locus_tag="IEY95_RS40945"
                     /old_locus_tag="GCM10011579_083390"
     CDS             7094..7771
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016433207.1"
                     /locus_tag="IEY95_RS40945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_083390"
                     /product="AIM24 family protein"
                     /protein_id="WP_189191329.1"
                     /transl_table=11
                     /translation="MKGDLFSSDHMVQPALAPGMTIQNAKSIRYAVNGEMFARQGAMVA
                     YRGNLQFERKGQGVGGMLKRAVTGEGLPLMTVRGQGEVWFAHEAQNCFIVGIEPGDVFT
                     VNGRNVLCFDATLSYEIKTVKGAGITGGGLFNSVFTGHGSLGMICEGNPLVIPVSQQQP
                     VYVDTDAVVGWTAHLHTSLHRSQSIGSMIRGGSGEAVQLKLEGEGYVVVRPSEVTPQKA
                     QQH"
     gene            complement(7895..9673)
                     /locus_tag="IEY95_RS40950"
                     /old_locus_tag="GCM10011579_083400"
     CDS             complement(7895..9673)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069211.1"
                     /locus_tag="IEY95_RS40950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_083400"
                     /product="M4 family metallopeptidase"
                     /protein_id="WP_189191330.1"
                     /transl_table=11
                     /translation="MRRPHIRRVAIAVAVTTAATLPAGPVFAATPDSPARPATSASSTV
                     DAARAAAFAHASATGVTQGDTLQAKDVMTDPDGKQHVRFVRTHQGLPVLGGDVVVHLGK
                     QSAYLGVTRAVGHAVKPATTEAKLTPQQAEQKAAAVAKGDAGSAELVVDARDGAAALAY
                     QVRVTDSETAEAGGSSTVVVDARTGNIRSNTPDSDEFISPSLEETLRKRGEQATPETGT
                     ATQSTGLVGTTGATHYPVTATGSGKSLFVGTVTLKTTQTARTSFLLKDPTRWNTETRDA
                     RGQELEAFSRGKKFTDGDNKWGTGTTSSRTTAAVDAQYGITKTLDFYKKTFGRKGIKNN
                     SAGARAMVHFGNKVGNAFWDSTCGCMLYGDGDGDLFKKPLVVLDVTGHELTHGVVDATA
                     ALEPTRVDQDGNQFGEPGALNESLADIFGSNVEFATNNPNNPPNYLVGEKLGLAQKFLR
                     RLDRPSLDRLEGTIDYWSPAAYDTEVHAGSGVSSHAYYLLAEGSGRKTIGGVQYDSPTY
                     DGSSVTGIGRAKATAIFYRALTRYMVSTTDFHDARKATLKAAADMYGANSTEYKTVDKA
                     WAAVNVTTANTPAAGH"
     misc_feature    complement(9761..9773)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 20.37"
                     /tool="antismash"
     misc_feature    9832..9847
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.39"
                     /tool="antismash"
     misc_feature    complement(9942..9957)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.6"
                     /tool="antismash"
     gene            complement(10001..11050)
                     /locus_tag="IEY95_RS40955"
                     /old_locus_tag="GCM10011579_083410"
     CDS             complement(10001..11050)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014157796.1"
                     /locus_tag="IEY95_RS40955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_083410"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_189191331.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.3e-63, bitscore:
                     208.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSTALQSPPAAPLVLRRCRDLVAPALAEAIGGLHPWVAEMAGYA
                     LGRCEIGGAPATHSQGKGVRQALAVLGAEAAGGSGEAGVPGAVAVELVHTFSLLHDDIM
                     DGDALRRGRPALWKAYGTGPAVLAGDALFALAVETLAAGPATAHAAAAVRHLTTALRDL
                     VRGQADDLLFADRPWTGPEAVGVGEYEAMAEHKTGALLGCALALGAQLAGAPRETAIAL
                     DRAGRHLGVAFQIADDLLGIWGDPAITGKPVHGDLRQGKKTLPVLVALNAPGHPALAGL
                     LASPADLDDSGVRKAAALVERAGGRAGALREARRHLAAADALLATASLAPRPAEELRSL
                     LSSLAHRTI"
     gene            complement(11047..12108)
                     /locus_tag="IEY95_RS40960"
                     /old_locus_tag="GCM10011579_083420"
     CDS             complement(11047..12108)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982568.1"
                     /locus_tag="IEY95_RS40960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_083420"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_189191332.1"
                     /transl_table=11
                     /translation="MYGKAFAPEYQGALTTLSVNSSLTDVLAAGTEQLRAAERSGARAE
                     AARSGLAVAEAHRRLGQVADADRAWKASYRTAREAGDTGAMAWALWSGGTLARQRGAFP
                     LAWRLLRLAAELGGQAGDVVVRGYSLAGMAETGRIQGDYAAVTSLHEQLLAEARKRGEA
                     RHTVWALEGIAQIHRNTGAYDTAYAMFEEAAEIAARAEDRRGHAWALRGLADIVSVRDQ
                     DVDRALDLLSEAEVSCRAMNLSGALAYNHKMRGNVLYRAGRYEQAREVYAQALAEFEAM
                     SEPRGRALSRLGLVKSLARLGRDRAETAADLAELARVLEGIGLRHARQMVERARTELGL
                     TPESEGADAEAAR"
     misc_feature    complement(12262..12277)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 19.13"
                     /tool="antismash"
     gene            12444..13334
                     /locus_tag="IEY95_RS40965"
                     /old_locus_tag="GCM10011579_083430"
     CDS             12444..13334
                     /EC_number="2.7.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014181582.1"
                     /locus_tag="IEY95_RS40965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_083430"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_189191333.1"
                     /sec_met_domain="APH (E-value: 2.1e-32, bitscore: 106.3,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSGPMHAHEARIDDALVRRLLAAQFPNWADLPLKRVESSGTVNA
                     IYRLGADLAVRLPRIPEGAGDVDKEWEWLPRLAPLLPFAIPEILAVGAPGEGYPWPWAV
                     LRWLDGELPVSGRLTDAGALAADLGGFVRALQQVDLPGGPPAYRGGPLASVDDATRSAI
                     AELHGTIDTTAATAAWEAALRAPLWTGPPAWVHSDLMPMNLLTRQGCLTAVLDFGTVGT
                     GDPACDLIAAWNLLPAEVRPTFRHAVGTDDATWARGRGWALSMALLQLPYYRTTNPAIA
                     ANAEHVIREVLGDLD"
     gene            complement(13823..14665)
                     /locus_tag="IEY95_RS40970"
                     /old_locus_tag="GCM10011579_083440"
     CDS             complement(13823..14665)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014141235.1"
                     /locus_tag="IEY95_RS40970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_083440"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_189191334.1"
                     /transl_table=11
                     /translation="MASTEFGQTVRRWRDRVSPEAAGLPAGGHRRAAGLRREELALLAG
                     ISVDYITRLEQGRATNPSEQVVEALGRALRLSAGERAHLFQVAGLVPPGRDSVPAHITP
                     SVQRLLDRLAGTPVAVYDAAWTLLLVNPLYAALMDDPSSWRGNERNGIWRNFVGPGSRV
                     RRSPEAQRAFEAALVGDLRATASQYPADERLRRLIAELRANSDRFAELWDSGAVGRHEA
                     SRKTVHHPQVGPLTLDCDVLSVAGSDLRIMIYTAEPDTEDAERLELLGVLGTQALVES"
     gene            14767..15474
                     /locus_tag="IEY95_RS40975"
                     /old_locus_tag="GCM10011579_083450"
     CDS             14767..15474
                     /NRPS_PKS="Domain: PKS_KR (2-137). E-value: 2.7e-08. Score:
                     25.9. Matches aSDomain:
                     nrpspksdomains_IEY95_RS40975_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386472.1"
                     /locus_tag="IEY95_RS40975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_083450"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_189191335.1"
                     /transl_table=11
                     /translation="MTTTLITGANKGLGFETARRLVAAGHTVYLGSRDPERGHRAAEQL
                     GARLVVLDVTDDASVAAAAKTVEADGGLDVLINNAGVEQRGAGNTVIGAADVTAAMMRD
                     VFETNVFGVVRVTHAFLPLLQRSAAPVVVNVSSGLGSMAHVTDPAAPAYAYPGVAYPAS
                     KTTVNMITVQYAKAFPAMRINAVEPGYTATDLNGRTGTQTVEEGAEIIVRMAQIGPDGP
                     TGGYFDAEGPLPW"
     aSDomain        14773..15177
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEY95_RS40975_PKS_KR.1"
                     /evalue="2.70E-08"
                     /label="IEY95_RS40975_PKS_KR.1"
                     /locus_tag="IEY95_RS40975"
                     /protein_end="137"
                     /protein_start="2"
                     /score="25.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TTLITGANKGLGFETARRLVAAGHTVYLGSRDPERGHRAAEQLGA
                     RLVVLDVTDDASVAAAAKTVEADGGLDVLINNAGVEQRGAGNTVIGAADVTAAMMRDVF
                     ETNVFGVVRVTHAFLPLLQRSAAPVVVNVSS"
     CDS_motif       14779..14841
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEY95_RS40975_0001"
                     /evalue="1.50E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="IEY95_RS40975"
                     /protein_end="25"
                     /protein_start="4"
                     /score="17.7"
                     /tool="antismash"
                     /translation="LITGANKGLGFETARRLVAAG"
     cand_cluster    14885..25271
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="melC"
                     /kind="single"
                     /product="melanin"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    14885..25271
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[19884:20271](+)"
                     /cutoff="20000"
                     /detection_rule="melC"
                     /neighbourhood="5000"
                     /product="melanin"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      19885..20271
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="melC"
                     /neighbourhood="5000"
                     /product="melanin"
                     /protocluster_number="2"
     misc_feature    complement(15496..15510)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: strong, score: 21.47"
                     /tool="antismash"
     misc_feature    complement(15496..15511)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 23.63"
                     /tool="antismash"
     misc_feature    complement(15497..15510)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.55"
                     /tool="antismash"
     misc_feature    15530..15543
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: strong, score: 19.46"
                     /tool="antismash"
     gene            15533..16159
                     /locus_tag="IEY95_RS40980"
                     /old_locus_tag="GCM10011579_083460"
     CDS             15533..16159
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670739.1"
                     /locus_tag="IEY95_RS40980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_083460"
                     /product="alpha-ketoglutarate-dependent dioxygenase AlkB"
                     /protein_id="WP_189191336.1"
                     /transl_table=11
                     /translation="MAMHLQGSLFDQTDEVCLGPLNGLRRTALGDGAWIDLLPGWLGGA
                     DALFARLAAEVPWRAEQRQMYEHTVDVPRLLAYYRAGDLLPHPILDEARDALSARYAAE
                     LGEPFTTAGLCYYRDGRDSVAWHGDRIGRGAREDTMVAILSVGAPRDLLLRPRGGGDTV
                     RRPLGHGDLIVMGGSCQRTWEHSIPKSARAAGPRISIQFRPHGVN"
     gene            complement(16202..16801)
                     /locus_tag="IEY95_RS40985"
                     /old_locus_tag="GCM10011579_083470"
     CDS             complement(16202..16801)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019057091.1"
                     /locus_tag="IEY95_RS40985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_083470"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_189191337.1"
                     /transl_table=11
                     /translation="MSTVTTPHPGLTTPPAAPPRRDAEATKAAILLAARHLLARHAHAD
                     ITLKAVADRAGVSAPLILKYFGNKDALFARVMSFESDAEALLDAPVEDLGRHMVRHLLE
                     GQTQRGADPILRIVFAPIQGEQGDILRTNFRAQVSDRLAERLSGPQAGLRAELAVSTLL
                     GLGVMYGIARGTRLRATAIEDIVDRYAPTVQAQLTP"
     gene            complement(16798..18264)
                     /locus_tag="IEY95_RS40990"
                     /old_locus_tag="GCM10011579_083480"
     CDS             complement(16798..18264)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016433221.1"
                     /locus_tag="IEY95_RS40990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_083480"
                     /product="MFS transporter"
                     /protein_id="WP_189191338.1"
                     /transl_table=11
                     /translation="MSTSGAFMAALRDRLAVPVLAFGGILMAVMQTVVVPLLPDLPRLT
                     GASASAVSWMVTATLLSGAVLTPVLGRAGDMYGKRRVLLMALGLMTVGSLLCALTSDIG
                     VLIAARALQGAAAAVVPLSISILRDELPPERTGSAVALMSSTVGIGAALGLPLAALIVQ
                     YANWHVMFWATTVLGAVGLALAWWAVRESPVREPGRFDTVGAMGLAAGLVCLLLGVSQG
                     GTWGWGSPRILGLFVACVVIMTLWWIQQRRTERPLVDLKLAARPRVALPHVAALLTGFA
                     FYGNSLVTAQLVQAPKESGYGLGLSIVATGLCLLPGGVTMLFLSPVSARISAARGPRVT
                     LALGTAIIALGYVIRILDSRELWLIILGATVCAIGTTLAYSALPTLILRAVPAGQTASA
                     NGVNVLMRTIGQAVCSAAVAAVLVHHTSLVGGAPLPTLHGYLLAFAMAGTVALVACAAA
                     LSIPADPASPDTRGAVGRTGVPRDEALEGA"
     gene            complement(18344..19546)
                     /locus_tag="IEY95_RS40995"
                     /old_locus_tag="GCM10011579_083490"
     CDS             complement(18344..19546)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982572.1"
                     /locus_tag="IEY95_RS40995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_083490"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_189191339.1"
                     /transl_table=11
                     /translation="MEIACVGGGPASLYFSILMKRQDPSHDIAVYERNPAGSTYGWGVT
                     YWAGLLEKLGEGDPESALAVAENSVRWSDGVAHVGDRTTVHHGDEGFGIGRRRMLDLLA
                     ERATSLGVRVEFEHEIAADRLPDADLVIAGDGVNSALRERHADHFGTDIKLGRNTYIWL
                     GTTKIFDSFTFSFVETGHGWIWCYGYGFSEDHSTCVVECSPETWTGLGLDRTSEADGLA
                     LLEKLFADLLDGHGLIGRAQVDGSAQWLSFRTLTNRTWHRGNLVLLGDAAHTTHYSIGA
                     GTTLALEDAISLAGALREHPELECALTQYERARRSALLPVQSAARHSAQWYENLPRYIR
                     LPPAQMFALLGQRHSPLLPYIPPQLYYRIDRAAGQLEPLRRFKRWLGPRVARTVQARSR
                     R"
     misc_feature    19557..19570
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.13"
                     /tool="antismash"
     misc_feature    19558..19571
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.56"
                     /tool="antismash"
     misc_feature    complement(19854..19868)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 19.86"
                     /tool="antismash"
     gene            19885..20271
                     /locus_tag="IEY95_RS41000"
                     /old_locus_tag="GCM10011579_083500"
     CDS             19885..20271
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     melanin: melC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020138613.1"
                     /locus_tag="IEY95_RS41000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_083500"
                     /product="tyrosinase cofactor"
                     /protein_id="WP_189191340.1"
                     /sec_met_domain="melC (E-value: 6e-53, bitscore: 172.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPELTRRRALGAAAALTVVVGTQALTAPAVSAAPGMSTGEHHHGG
                     PEAFDEVYRGRRIEGRPVSGGGHHHGAGYAVFVDGVELHVMQNADGSWISVVSHYAPVP
                     TPRAAARAAVVELQGAPLVPFNAN"
     gene            20305..21129
                     /locus_tag="IEY95_RS41005"
                     /old_locus_tag="GCM10011579_083510"
     CDS             20305..21129
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662973.1"
                     /locus_tag="IEY95_RS41005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_083510"
                     /product="tyrosinase family protein"
                     /protein_id="WP_189191341.1"
                     /transl_table=11
                     /translation="MTVRKNQASLTADEKRRFVDALVQLKRSGRYDAFVTTHNAFIMGD
                     TDSGERTGHRSPSFLPWHRRFLIEFEQALQSVDSTVALPYWDWSADRSTRSSLWAPDFL
                     GGTGRSLDGRVIDGPFSASSGNWPINVRVDNRTYLRRSLGSGARELPTRAEVESVLAMA
                     TYDMAPWNSASDGFRNHLEGWRGVNLHNRVHVWVGGQMATGVSPNDPVFWLHHAYIDKL
                     WADWQRRHPDSGYLPTAGTPDVVDLGETMKPWKDVRPADLLDHTAYYTFDAA"
     gene            21222..21860
                     /locus_tag="IEY95_RS41010"
                     /old_locus_tag="GCM10011579_083520"
     CDS             21222..21860
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY95_RS41010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10011579_083520"
                     /product="hypothetical protein"
                     /protein_id="WP_189191342.1"
                     /transl_table=11
                     /translation="MSGVLIMEPVLETYEAADFTLWPTADQPADRLLVLSGDLSPLEVG
                     TAMAVLAGYNKTQRRRHDPGPADGLAMLRRLVSVESVVAPGGLRLQDSATGVTVPPGCC
                     FGLENWRDWQGLLDGETPWLGHDPTPGVEPSGSLVRLWPDAERPAGLPIELALSELPVL
                     LESVRSALTGFLGLVEGWTVRDFPAALAARVVAKLDEDLAMSGSLREVS"
     gene            complement(21870..22571)
                     /locus_tag="IEY95_RS41015"
                     /old_locus_tag="GCM10011579_083530"
     CDS             complement(21870..22571)
                     /EC_number="3.1.26.4"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009308694.1"
                     /locus_tag="IEY95_RS41015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_083530"
                     /product="ribonuclease H"
                     /protein_id="WP_189191343.1"
                     /transl_table=11
                     /translation="MIGAMPERVVAACDGASKGNPGPAGWAWVVADGEETPTRWEAGPL
                     GTATNNVAELTALERLLTAIAPDVPLEIRMDSQYAMKAVTTWLPGWKRKGWKTAAGKPV
                     ANQELVARIDELLDGRAVEFRYVPAHQVDGDRLNDFADRAASQAATVQQPAGSDLGSPE
                     PPPSPDSPAPARRRNSTKTAARPNASSRTIKAKFPGRCVCGRSYAAGEPIAKNGQGWGH
                     PECRTAETSNA"
     gene            complement(22626..23624)
                     /locus_tag="IEY95_RS41020"
                     /old_locus_tag="GCM10011579_083540"
     CDS             complement(22626..23624)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015609099.1"
                     /locus_tag="IEY95_RS41020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_083540"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_189191344.1"
                     /transl_table=11
                     /translation="MLRIHFTSHDLQNIRVAREPDPLWELMCSVCRLETGQGPLDFGHW
                     RRAAHDRLSQDTVAGRALHPLRALIPAAGYIPDFLTPPVTGGGLSAGLDQLRRTPRARM
                     VRELTRLAESRPVPSWTTSLGRPGSDALKSLAGALGIYFHALLEPYWSHIGTAVGNDVD
                     LRSRALLDGGTRALLDGLRPLARWRAPVLEVDYPTERDLYLEGRGLLLVPSFFCWRRPT
                     ALADPGLDPVLVYPVEKAPLAVARGTDDGLERLLGRTRAAVLTEVANRTARTTSEVALA
                     VGIALPSASYQIGVLRDGGLVTSRREGKYVLHVATPLGLRLLGAGSSSGAR"
     misc_feature    23583..23597
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.48"
                     /tool="antismash"
     gene            complement(23736..24533)
                     /locus_tag="IEY95_RS41025"
                     /old_locus_tag="GCM10011579_083550"
     CDS             complement(23736..24533)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031563.1"
                     /locus_tag="IEY95_RS41025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_083550"
                     /product="VOC family protein"
                     /protein_id="WP_189191438.1"
                     /transl_table=11
                     /translation="MAVQPEGKPCWADAMFSDVEGAKSFYGDVLGWTFGESSSEYGNYT
                     QAYANGKAVAAVVPPMPGQEGQSAWCLYFASPDAAATATKIRDNGGEVLMEPMQVGEFG
                     TMVLARDPSGAVFGVWQAGIHEGFEATAVPGAYAWAEVFTREPEKSDAFFPAVFPLSAK
                     QVEDDAVDFRIFSLGEEPVLGRMKMTDDFPPEVPPYVNVYFTVENCDAAVAKATERGGI
                     LRFGPMDSPFGRFAALSDPQGASFSVIDMTTTRGDMPKTTDVS"
     misc_feature    24669..24682
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.54"
                     /tool="antismash"
ORIGIN
        1 tggcgccggt gggacagccg accacgcact ggcacgagcc cttgcagccg ggcgcgttgc
       61 ggcgcagtgg tccggcccgc cagccgagcc ggtcggcgcc cgcaagggcg agccgcccgt
      121 tgttgcccag cacgtcgagc ggctgggtgg ccacgcgcag ggtgcgctcg atctcgtcga
      181 gccgggggcc gagggcctcg gcgatcccga acccgtagtc cttgctccat cgggccagca
      241 catggtccgg agtccggtag caggtgccgg agttgaccac ggtggtgccg ccgacggcgc
      301 ggccgaccgg cagcaggagc ggcgggttgc cgacggccac cgtggcgccg ccgtcccggt
      361 acagctcggt gaatctgtcg agcggcgccc ggcggccgaa ggacgccgtc gagtggtgtt
      421 cgccctcctc caggaggacc acgctcagtc cggcgagcgc gaaggtccgg gcggccacgg
      481 caccgccggc gccggatccg acgaccacca cgtcggcggt ggagcgtgtc ggccactcct
      541 gggcgggagt gcagtcgagc ggcggatcct cgggcgccct cgcggaaacg ggcgcggacg
      601 gcatcctctc ggtgcccgcc gcgagcatca cgggcacctt gaggatgtcg agcagcggga
      661 cgagccgggg ccgtgcggcc agcgagccga gaacgctctc gcgttcgtcg gggtcgagtg
      721 ccgccaggcg tctgccggtg cgcaggacgg cgtacgtgtc cagggccgcg acggcggtgt
      781 gcaccccggc ccgggcgggc cggggcagcg cggcgagcac cgtgtcgagc cggtgcggca
      841 cacgggacgg ccagtcctcg tcgccggcgt cggcgagcag cgccgcgacg aagccgtcgg
      901 cggtcaccgt tcgcccgcct cggcgtgcgc ggtgccgtcc aggagccagg tggcctccgg
      961 gcgccaccgg ccccaccagc gttccagcac gatgcgggcg tcggcggact cgctgttgcg
     1021 gcacacggcg cgggctccgt ccgggtctcg gtactccagg gtgagggttc gctcggccgg
     1081 ctggtcgacc tcgacgcgga tgcggcggaa tgccgtccgg ccggtcactg tccacttggg
     1141 cagaccgaac acggcccgga accgtcccat gcccagccag ccgagggccg tccgctccgc
     1201 ccggcgcggc caggtcctgc cgcggcggcg caggcgcagg aagaccagtg gaggaagccg
     1261 ccgcaggccc ggccgggtgg acacggcggc cacgatctca aggacgtcgc caccgcccag
     1321 ctccgcatgc agccaggtcc accggtgtgc attgccgtgc ccgtagatgc gggccgaggc
     1381 gccgggcgcg ccgcgcaggg tcaaggcctg ttcaccgtag gagaattcgc cctcgtaggt
     1441 ggcccgcgcg gccgggagca tctgggctgc gggcagcagc ggccgacgcc aggaccagcg
     1501 cgggaaggtg aacagcggtt ccccttgggg gtgttcggtg agcttccagt ggaagtcacc
     1561 ggcgttccct gtcagttccc ctgggacgac cgtgacgttg tctcccgcga agccgtccgc
     1621 gggccgggtc caggggaccg gcccgaagcg ggcgtgccgc accgcgccct cgcgagggaa
     1681 cgcggccacc catccgtgcg cgaacggctc ggatccgtcg gcgggtgcgg tcacttcgtg
     1741 gtgcagccag acgccggtgc cactcgccgg atcggtcagt gtggtgtacc agacctcggt
     1801 gcggcccggt tcgccgttcc aacgcggtgg gaagtgctcc gcgctgctct cacggcgcgg
     1861 gaagcggaag ctgaggagga acggcgcgag gccggtcgcc agcgggaagc ggagcactcc
     1921 ttcgccgacc cgtgcgtcgc cctcgtacag cgtgaacggc aggacggtca tcgactcgac
     1981 cggccggcgc gcggtcacgg acttccagcc gtccagggtg aggcggcggc cgtcggcggt
     2041 gaacgcgagt tgatagcgga tgcggcgtcg tgcgagtggt gacacctcca actcgccctc
     2101 ggcgcggggg tcgtcggcga atccggcgat ccgtactcgg ccggtcaggc gtgccggtgt
     2161 ggtgcggtgc gggcgcagta tgccgtcggc ttcggcgtgc aggtcgaggc gtatgcggcg
     2221 ctcccgtgtc ttggcgtcga gccggatcgt gccgagcatc gtctccgtga acgccgtgcc
     2281 cctcatgcga gaccctccag catgatgcgc tcggtggccc gcaggtaggc atcggccgcc
     2341 gcgtgcgcct gccgggcgtc ctgggccgtc accgccgcca ccaccggcgc cagccgttcg
     2401 taggccgccg acggatcggt gaagggcccc ttgagcagag agcggacggg caggtaggca
     2461 ttgaagagcg tgttcgtcag caggaggtag acgcggttgc cggtggcccg ggcgagcgcg
     2521 cggtgcacct cgacgtcggc cagctgcacc gcgtcggcgc cgtcggcctc ccgcactgcc
     2581 tccagcagca catggagttg cgcgcactgc ttgcgggtgg ccctggacgc ggctcgctcg
     2641 gcgatcaacg cgccgacgcc gcgccgcact tcgaagatct cgtggaccca tttcgcgtcg
     2701 tgccgcacga gcatgggcag caggtccgcc ccgcccaggc gcgcgtagtc gcgcaccctg
     2761 gtcccgactc cgtgccgggt ttcgagcagg cccgcctgga cgagtcggcc gaaggcgtgc
     2821 ttgagcgtcg tgcgggtgac tccgtagccg tcggcgagtt ggcgctcggg gggcagataa
     2881 ctccccgctg gatgacggcc gtcgagtatg tccgtgcgca gccggtcctc caggacgtcc
     2941 acgatggtct cgcggggcag tgcctccacg gttctcccct ccgagcaggt ggatgagtgg
     3001 ctgatccact gaatcagtgg aggcctgccg cggtcaaccc ttcgccgcaa gacggccgtt
     3061 ggcgcacatt cgacagccgc gactcaccgg cggccacccg ccgccgaccc gagcgcgcga
     3121 ttggaccgga ccaaccccgt ccgaatcgtt gacatgtacg ccaccgggcg caactctgaa
     3181 aaggccgtga gagcgctctc agagcgatgc cggacggagg aagacgatgc ccagaaagat
     3241 cagatggcgg gcgttagcgg tggccgtggc caccctcgcc acggcactgg tgacgttcgg
     3301 gaccccgtcc cgggccgagg ccgccgtccc ggcgaccatc ccgctgaagt tcacgaacaa
     3361 ctccggccga agcgacccgg tgtacatcta cgacctcgga acacagctgt cgacaggccg
     3421 gcagggctgg gccgacgcga acggcacgtt ccacgcctgg cccgcgggcg gcaatccacc
     3481 gacgcccgcg cccgacgcgt cgatcgtggg accggcgaac gggcagtcca agaccatccg
     3541 gatccccaag ttctccggac ggatctactt ctcgtacggg cagaagctcg acttccggct
     3601 gacgaccggc ggtcttgtgc agccggccgt gcagaacccg agcgacccca accgcaacat
     3661 cctcttcaac tggtccgagt acacactcaa tgactccggt ctgtggatca acagcacaca
     3721 ggtcgatatg ttctcggcgc cgtacgccgt cggcgtccag ctcgccgacg gcacgacgaa
     3781 gaacaccggc catctcaagg cgggcggata caacggcttc ttcaacgccc ttcgaggtca
     3841 gcccggcggc tgggccaacc tgatccagac ccgctccgac ggcaccgtac tgcgggccct
     3901 cgcccccggt cacggcatcg aggcgggcgc gctgccgagc acggtcatgg acaactacgt
     3961 caaccgggtg tggcagaagt acagttcgtc gacgctgacg gtgacgccgt tcgccgacca
     4021 accgaacacg aagtacttcg gccgggtctc cggtgacgtc atgaacttca ccaacagcgc
     4081 cggggccgtc gtcaccagct tccagaagcc cgactccgac agcatcttcg gctgctacaa
     4141 gcggctcgac gcacccaacg acctggtgcg cgggcccatt tcacgcaccc tgtgcgcggg
     4201 cttcaaccgc tccacgctcc tggtcaatcc ccaccagccg gacacgagtt cggccaactt
     4261 ctaccaggac acggtgacca accagtacgc ccgcaagatc cacgcgcaga tggccgacgg
     4321 gaaagcctac gcgttcgcgt tcgacgacgt cgggaactac gagtcgctcg tccacgacgg
     4381 caatccgcaa caggcgtacg tcacgctgga cccgttcaac tgacggcagt ggagggcggc
     4441 cggggctccg gccgccctct cacccggcgc cctcggagtc caggcagagt accgggaccc
     4501 gctggacgag gttgttcgcg aaaccgcccc ggttccacgg ctggtccagc ggctgggtgt
     4561 ggccctcggc gtcgacggcc cgcgcgctga gcacatgagg gccgggggtg gccgtccagg
     4621 cgaaacgcca gggtcgccag gcccagcggt gctcatcgcc tccgtcgaga tcggccgcgc
     4681 accaagaacg ctccgcgtcc gtgctgacct cgaccccggt caccggcgcg cgccccgacc
     4741 aggcccgtcc ctccagcgtc acggcacccg gccggaccac ccgcgtcctg gacatgaagt
     4801 ccgggaatcc gggcgggatc agcagggccc ggggggcgat ccgggtgacc ggttcgccct
     4861 cgtcccccgc gtcccgccga agtcgatagg ccacggcctg ctggaatccc gtgaacgacg
     4921 tgtccgtcac cctgatctcg cgcagccact tcacatgcgc catgccgtac cagccgggca
     4981 ccaccaaccg caccggatgt ccgtgctgcg gcggcagcgg gccaccgttc atctcgtacg
     5041 ccacgagcac ctcgggttcg ccgcccatgg ccacgtcgag cgcaagggcc cgctgatagt
     5101 cctgctcgac accgcgctcg acgccatgat cggcgccggt gaacacgacg tccaccgccc
     5161 cgggttcgac cccggcctcg gtgagcagca cccgcaacgg cacaccggtc cactccgccg
     5221 taccgaccgc ctccaccagc cacggctggc tgacgggccg gggcgtcaag agggctcgcc
     5281 cattgcccgc acactccagc gtcacccgcc gcgtgaccgc gggatacgcc ctcagctcat
     5341 ccatcccgag caccagcggc cgccgcactc cgcccccgac gacgagctcc cacgccccct
     5401 ctggcacata gggaatgtcg tagtgcgtca gcacatagtg cagccctggc ggcgtcacgt
     5461 cgtaccgcag cgcctccaac ggcatcccgt gattccgagc ggcgagcgcc agctcctcct
     5521 gactgatgcc ttcttccggc tcggccagcc gagcgggtgc gcttacttca tcgaggcggt
     5581 ggcccatgcc cgcattgtcc gccttcccgc caaggcggcg ccaggcggtc acctcgtact
     5641 ccgctccacc aggtcgtgcc agcccgcctc caaacgctcg atggacatgc cgcgctggcg
     5701 ggtcaggtgg tgcaacaggg cgggttccag gtatcccatc agggtctggg cgacgagttc
     5761 gatgtccgtg gtcgggtcgg cctggcgcag cagcatgcag acgtgcatga agcggacgcg
     5821 gtacggggcg gagccgaagc ggcgggaggc ttcgggctcg gcggcgaggt agaggtcgag
     5881 ctgctcggag gcctggcgga gggcccgaca gccgaaggcg tggagacgct ccaccggtga
     5941 cgcgccgggg ccgagcgggg gtggaccgct gatgaagtcg gtctggaacc gctgctcggt
     6001 gtggtcgagg agtgccatca gaaggccggt gcggtcgccg aatcgccgga agacggtccc
     6061 cttgcccacc gaggccgcgg cggcgacggc atccatcgtc agcttggcca ccccgtgctc
     6121 ctccaccagg tgggcggcag cctccagcag acgcgcgcgg ttgcgtgctg cgtcggcgcg
     6181 cagctggggc gcctcgctgg gggcggtgag ctccatcagc acgggttcgt cggacggttc
     6241 ctggcgcttc gggaagcgcg ggagtggggt ggacatgagg ccagagtagc ccgagaccag
     6301 ggaaactgga ctgtggtccg gttcagtgat acacatttaa ccggacctcg gtccgcttta
     6361 ttgcggcaat gtttcagctt cgggagatca ccatgtctgt acgtatcctc gcgctcgtcg
     6421 gcagcctgcg cgccggctcc cacaaccgtc agctcgccga ggcggccgtc aagctcgccc
     6481 cggagggcgc ggaggtcgag ctgtacgagg gcctggccga ggtcccgttc tacaacgagg
     6541 acatcgacgt cgagggcagc gtccccgcca ccgccgcccg gctgcgcgaa gccgccggcc
     6601 gcgccgacgc cttcctgctc ttctcgcccg agtacaacgg cacgatcccg gccgtactga
     6661 agaacgccat cgactggctg tcccgcccct atggcgccgg cgccttcatc ggcaagcctg
     6721 tcgccgtggt cggcaccgcg ttcggccagt tcggtggcgt ctgggcacag gacgaggccc
     6781 gcaaggccgt gggcatcgcc ggtggcaccg tcctggagga cgtcaagctc tccatccccg
     6841 gctccgtgac ccgcttcgcc gagacccacc ccgtcgacga cgccgaggtc gccgggcagc
     6901 tcacggaggt cgtcagccgc ctgcacagcc aggtcggcgc ggccgacgcc gcctgacaac
     6961 tgccctgagg gccggtccgg ttcacccggg ccggcccttt cgcgtgtcac aagatcgctg
     7021 ttgaatgtct caggtccgca cgatggtccg cacgatcttg gcggaacgaa atcctccggg
     7081 tcacgatgcc cgcatgaagg gtgatctctt ttccagcgac cacatggtgc agcccgctct
     7141 cgcgccgggc atgaccatcc agaacgccaa gtccatcagg tacgccgtca acggcgagat
     7201 gttcgcacga cagggggcga tggtcgccta ccgggggaat ctgcagttcg agcgcaaggg
     7261 ccagggcgtc ggcggcatgc tcaagcgggc ggttaccggt gagggactgc cgctgatgac
     7321 cgtccgcggg cagggcgagg tctggttcgc gcacgaggcg cagaactgtt tcatcgtcgg
     7381 catcgagccc ggcgacgtgt tcaccgtcaa cggccgcaac gtcctgtgct tcgacgccac
     7441 gttgtcgtac gagataaaga ccgtgaaggg cgcggggatc accggcggtg gcctcttcaa
     7501 cagcgtcttc accggccacg gcagcctcgg gatgatctgc gagggcaacc cgctggtcat
     7561 ccccgtctcg cagcagcagc cggtgtacgt cgacacggac gcggtcgtcg gctggaccgc
     7621 ccatctgcac acctcgctgc accgctcgca gtcgatcggc tcgatgatcc gcggcggctc
     7681 cggtgaggcc gtgcagctga agctggaggg cgagggctac gtcgtcgtac gtcccagcga
     7741 ggtgacacca cagaaggcgc agcagcactg acatcggcaa tgacggaggg tgccccgcca
     7801 cacggcgggg cacccttttc acccgtcggc gcccgggcct gtcacccttc gacgcaccga
     7861 tgcttcaccg gtcagtggcc ggatgcagca ctggtcagtg cccggcagcg ggcgtgttgg
     7921 cggtggtcac gttgaccgcg gcccaagcct tgtccaccgt cttgtactcg gtgctgttcg
     7981 ccccgtacat gtcggcggcg gccttgaggg tggccttccg cgcgtcgtgg aaatcggtcg
     8041 tggagaccat gtagcgggtg agcgcccggt agaagatcgc ggtggccttg gcacgtccga
     8101 tgccggtcac gctcgaaccg tcgtacgtcg gcgagtcgta ctgcacgccg ccgatcgtct
     8161 tgcgaccgct gccctcggcg agcaggtagt acgcgtgcga ggagacgccc gaacccgcgt
     8221 ggacctcggt gtcgtaggcg gcgggcgacc agtagtcgat cgtgccttcg agccggtcga
     8281 gggagggacg gtccaggcga cgcaggaact tctgcgcaag gcccagcttc tcgcccacga
     8341 ggtagttcgg cgggttgttg gggttgttgg tggcgaactc gacgttcgag ccgaagatgt
     8401 cggcgagcga ctcgttgagg gcgccgggct ccccgaactg attgccgtcc tggtccacgc
     8461 gggtgggttc gagggcagcg gtggcgtcga cgacgccgtg ggtcagctcg tggccggtga
     8521 cgtccaggac gaccagcggc ttcttgaaca gatcgccgtc accgtcgccg tacagcatgc
     8581 agccgcaggt cgagtcccag aaggcgttgc cgaccttgtt gccgaagtgg accatcgcac
     8641 gggcaccggc gctgttgttc ttgatgccct tgcggccgaa ggtcttcttg tagaagtcca
     8701 gcgtcttggt gatgccgtac tgggcgtcga ccgccgcggt ggtccggctg gaagtggtgc
     8761 cggtgcccca cttgttgtcg ccgtcggtga acttcttgcc gcgcgagaag gcctccagtt
     8821 cctgccccct ggcgtcccgc gtctcggtgt tccaccgggt ggggtccttc aggaggaagc
     8881 tggtgcgcgc ggtctgggtg gtcttcagcg tgaccgtgcc gacgaagagg gactttccgc
     8941 tccccgtggc ggtgaccggg tagtgggtgg ctcccgtcgt gccgaccagt ccggtcgact
     9001 gggtggccgt acccgtctcg ggggtggcct gctcgccccg cttgcgcagc gtctcctcca
     9061 gggacggcga gatgaactcg tcgctgtcgg gggtgttgct gcgtatgttg ccggtccggg
     9121 cgtccacgac gaccgtgctg gagccgccgg cctccgcggt ctcgctgtcc gtcacgcgca
     9181 cctggtaggc gagggcggcc gcgccgtcgc gggcgtccac cacgagctcg gcgctgcccg
     9241 cgtcgccctt ggcgaccgcg gcggccttct gctcggcctg ctggggcgtc agcttcgcct
     9301 cggtggtggc cggcttgacc gcgtggccga cggcccgggt cacaccgagg taggcggact
     9361 gcttgccgag gtggacgacc acgtcgccgc cgaggaccgg aaggccctgg tgggtgcgga
     9421 cgaagcggac gtgctgcttg ccgtccgggt ccgtcatgac gtccttggcc tgcagggtgt
     9481 cgccctgggt gacaccggtc gccgacgcgt gcgcgaaggc ggccgcacgg gcggcgtcga
     9541 ccgtcgagga ggccgaagtc gccgggcggg cgggcgagtc gggcgtggcc gcgaagacgg
     9601 ggcccgccgg gagcgtggcg gccgtcgtca ccgcgacggc gatcgccacg cggcgtatgt
     9661 ggggtctacg cactgaattc cttcgaacag ggcagccggg atcaccaact gccatgagag
     9721 acagcaccgt tgggcactgt gggagctgtc gggcccccat gtgacaccct caccgattcg
     9781 ccatgtccat gtaaagacta aagatccctt ttattgattt acgggcgatc tctttacgaa
     9841 tgttcacttc tcggtgatca acaggtgacc aactgtgcgc cgctcggaca gatgtgaggg
     9901 gggatgaggc ggttgcccga caaggcccgc agacacgtac atgtgacgga tgtcgcagcg
     9961 cctccggccc ggagcggacg ggtccggagg cacggaggtg tcagatcgtc cgatgggcga
    10021 gggaggacag cagggagcgc agttcctcgg cgggacgcgg cgcgagcgac gccgtcgcca
    10081 gcagcgcgtc cgccgcggcg agatgacgac gggcctcgcg cagggcaccc gcacgaccgc
    10141 cggcccgctc gacgagggcc gccgccttgc gtacgccgct gtcgtcgagg tcggccgggg
    10201 aggcgaggag tccggcgagg gcgggatggc cgggcgcgtt cagggcgacg aggaccggga
    10261 gggtcttctt tccctggcgc aggtcgccgt ggaccggttt gccggtgatg gccggatcac
    10321 cccagatacc cagaaggtcg tcggcgatct ggaaggccac tccgagatga cgcccggcgc
    10381 ggtccagcgc gatggcggtc tcccgcggcg ctccggccag ttgggcgccc agagccagcg
    10441 cgcagccgag cagagcgccg gtcttgtgct cggccatcgc ctcgtactcc cccacaccga
    10501 ccgcctcggg cccggtccag gggcgatccg cgaacagcag gtcgtccgcc tggccgcgga
    10561 ccaggtcgcg cagggccgtg gtcaggtgtc gtacggccgc cgcggcgtgc gcggtcgcgg
    10621 gccccgcggc gagggtctcc acggccaggg cgaagagggc gtcgccggcg aggacggcgg
    10681 ggccggtacc gtacgccttc cagagcgcgg gacgaccgcg gcgcagggcg tcgccgtcca
    10741 tgatgtcgtc gtggagcagc gagaaggtgt gcacgagttc caccgcgacg gcacccggca
    10801 cgcccgcctc accggaacct ccggccgcct ccgcgccaag tacagccagc gcctgccgta
    10861 cgcccttgcc ctggctgtgg gtcgcggggg cgccgccgat ctcgcagcgg cccagcgcgt
    10921 atccggccat ctccgccacc caggggtgca gtccgccgat cgcctccgcg agggccgggg
    10981 cgaccagatc acggcagcgg cgcaggacca gtggcgcggc gggcggcgac tgcagggccg
    11041 tggaggtcat cgggcggcct ccgcgtcggc tccctcggac tccggcgtca agccgagttc
    11101 tgtccgcgcc cgttcgacca tctgccgggc gtggcgcagc ccgatgccct ccagtacgcg
    11161 ggccagttcg gccaggtcgg cggcggtctc ggcgcggtca cggccgaggc gggccaggga
    11221 cttgacgagt ccgagccggg acagcgcccg gccgcgcggc tcgctcatcg cctcgaactc
    11281 cgcgagcgcc tgggcgtaga cctcgcgggc ctgttcgtaa cgcccggccc ggtagaggac
    11341 gtttccgcgc atcttgtggt tgtaggcgag cgcgccggac aggttcatcg cgcggcagga
    11401 cacctccgcc tcgctcagca gatccagcgc gcggtccacg tcctggtcgc gtacggagac
    11461 gatgtccgcg aggccgcgca gggcccaggc gtggccgcgt cggtcttcgg cgcgcgcggc
    11521 gatctcggcc gcctcctcga acatggcgta cgcggtgtcg taggcaccgg tgttgcggtg
    11581 tatctgcgcg atgccctcca gggcccacac ggtgtgccgg gcctcgccgc gcttgcgcgc
    11641 ctcggccagg agctgttcgt gcagggatgt cacggccgcg tagtcgccct ggatgcggcc
    11701 ggtctccgcc atccccgcca gggagtagcc gcggacgacc acgtcgccgg cctgcccgcc
    11761 gagttcggcg gcgaggcgca gcagccgcca cgccagcggg aacgcgccgc gctgccgggc
    11821 cagcgtgccg ccgctccaca gcgcccacgc catcgcaccg gtgtcccctg cctcgcgggc
    11881 ggtgcggtag ctcgccttcc acgcccggtc ggcgtccgcc acctgcccga ggcgacggtg
    11941 cgcctcggcg accgcgagac ccgagcgggc cgcctcggcc cgcgcccccg agcgctcggc
    12001 ggcgcgcagt tgctcggtgc cggccgcgag gacgtcggtc agcgaggagt tcacggacag
    12061 ggtggtcaaa gcgccctggt actccggggc gaaggccttg ccgtacatgt atgcctttcc
    12121 gtctgccacc agccggccgc gatcacgcgt cggccgccgg tccgagctgt tcctggttcc
    12181 tgtcggtcgg cggcgtgtga cgacccagct atacgctcgg cgtatacatg gcgtgtatac
    12241 gcggagggta tagtgctccg catttccatc tggaaatccc tggctcacca cggtgcccac
    12301 gccgcccacc cgttgccgat caagacgacg gcggcgcccg caaggttgcc tggtgtgacg
    12361 aggaggccaa aatccggtgc gcggaagccc gaacgaggct caggatggcg aaagttgacc
    12421 tctcccacag gaagcaggcg cccatgccgt caggcccgat gcacgcccat gaggcgcgga
    12481 tcgacgacgc gctcgtacga cggctgctgg ccgcacagtt cccgaactgg gccgacctgc
    12541 cgctgaagcg cgtcgagtcg tccggaaccg tcaacgccat ctaccgactc ggcgccgacc
    12601 tggccgtacg cctcccccgc atcccggagg gcgccggcga cgtggacaag gagtgggaat
    12661 ggctgccgcg gctcgcgcct ctgctgccgt ttgccattcc cgagattctc gccgtcggtg
    12721 cgcccgggga ggggtatccg tggccctggg ccgtgcttcg ctggctcgac ggagagctgc
    12781 ccgtctccgg gcgcctcacg gacgccggcg cgctggccgc cgacctcggc gggttcgtcc
    12841 gcgcgctgca gcaggtcgac ctgcccggcg ggccgcccgc ctaccggggc gggccgctgg
    12901 cgagcgtcga cgacgccacg cgctccgcga tcgccgaact ccacggcacg atcgacacga
    12961 cggccgcgac cgcggcctgg gaggcggcgc ttcgcgcacc gctgtggacc ggcccgcccg
    13021 cgtgggtcca ctcggacctg atgccgatga acctcctcac ccgccagggc tgtctcaccg
    13081 ccgtcctcga cttcggcacc gtcggcaccg gcgaccccgc gtgcgacctc atcgccgcct
    13141 ggaatctcct ccccgccgag gtgcggccca ccttccggca cgcggtgggc acggacgacg
    13201 cgacatgggc tcgcgggcgc ggttgggccc tgtccatggc actgctccaa ctcccctact
    13261 accgcacgac gaatcccgcg atcgccgcca atgccgagca tgtgatccgc gaggtcctgg
    13321 gcgatctcga ctaggtcgtg tccgcgaagt ccgtcggccg gtggccggtt ggttcgtgct
    13381 gcgtcatcat gagccgacat cgccatgacg gggagcagga gccgacatct ccccgcgggg
    13441 agcagaaacg gatggaaggc gcctctgtcc cgtgagtgac cacgccatct tccgtgagct
    13501 cgtcgaggag ggcttggacg actgggtccc ggtggaccag ctgctcgctc ttgccgagga
    13561 cgtcgcgcac gaccggggcg cggacttccg tgacgtcggg gtcgagctgc tgcggcggct
    13621 gctcgacagc gggctgatgg ccgtcggcga tctcggcgaa agtggattcg aggcctggcc
    13681 ggagaccggc gacgaactcc tggccaaggc gatcagggtg ctcgacggct tcgaccggaa
    13741 tccacagggc ggcgcatact ggctggccaa cacgccgagg ggcgatgccg cggcctcggg
    13801 tcgggtcggg tcgggtggag tcctaggact ccacgagtgc ctgagtgccg agcacgccga
    13861 ggagttcgag gcgttcggcg tcctcggtgt cgggctcggc ggtgtagatc atgatgcgca
    13921 ggtcgctgcc ggcgacgctc agcacgtcgc agtcgagcgt caaggggccc acctgcgggt
    13981 gatgaacggt cttgcgtgac gcctcatgcc ggcccaccgc tccggaatcc cacagctcgg
    14041 cgaaccggtc gctgttcgcc cgcagttccg cgatcaggcg ccgcaaccgc tcgtccgccg
    14101 gatactggct cgcggtcgca cgcaggtcgc ccacaagcgc ggcctcgaac gcgcgctggg
    14161 cctcgggaga gcggcggacg cggctgcccg gtccgacgaa gttccgccag atcccgttgc
    14221 gctcgttgcc gcgccaactg gagggatcgt ccatcaatgc cgcgtacagc gggttgacca
    14281 gcagcagcgt ccaggccgcg tcgtagaccg cgacgggtgt cccggccagc ctgtccaaca
    14341 gccgttggac gctcggcgtg atgtgggcgg gcaccgagtc ccgtcccggc gggacgagcc
    14401 cggcgacttg gaagaggtgc gcacgctctc ccgcggacag ccgcagagct cggcccagcg
    14461 cctcgacgac ctgctccgac gggttggtcg cccggccctg ttcgaggcgg gtgatgtagt
    14521 cgaccgagat cccggccagc agggccagct cctcacggcg cagcccggcc gcgcgccggt
    14581 ggccgcccgc gggcaacccg gccgcttcag gagagacccg gtcgcgccag cgccgtaccg
    14641 tctgcccgaa ctccgtactc gccatgccac cactgtgcac cgccgggcga ggacatgcct
    14701 ggtactgaca gtcccaggaa ggtgggactc ctggctgacc gcgccgacgg cgcggaacct
    14761 ggaggcatga ctacgacact gatcaccgga gcgaacaagg gtctcggctt cgagaccgca
    14821 cgccgactcg tcgcggcggg ccacaccgtc tacctgggca gccgggaccc cgagcgcggg
    14881 caccgggccg ccgaacagct gggggcgcgg ttggtcgtcc tcgacgtcac cgacgacgcg
    14941 tccgtcgccg ccgcggcgaa gaccgtcgag gccgacggcg gcctcgacgt actgatcaac
    15001 aatgccggtg tcgaacagcg cggtgcgggg aacaccgtga tcggcgcggc ggacgtgacc
    15061 gccgcgatga tgcgggacgt gttcgagacg aacgtcttcg gcgtcgtccg tgtcacccac
    15121 gcgttcctgc cactgctgca gcggtccgcc gccccggtcg tggtgaacgt gagcagcggc
    15181 ctgggctcga tggcccacgt caccgacccc gccgccccgg cgtacgccta cccgggcgtc
    15241 gcctatccgg cgtcgaagac cacggtcaac atgatcaccg tgcagtatgc gaaggcattc
    15301 ccggccatgc ggatcaacgc ggtcgagccc ggctacacgg cgaccgacct gaacggccgc
    15361 acggggaccc agaccgtcga ggagggcgcc gagatcatcg tccgtatggc gcagatcggc
    15421 cccgacggac ccactggagg ctacttcgac gccgaaggac cgcttccctg gtgagcgagg
    15481 cggccatcac gcctatggaa cacatattcg attccagggg tacgctggtc gcatggccat
    15541 gcacctccag ggttcgctct tcgaccagac cgacgaggtc tgtctcggtc cgctgaacgg
    15601 actgcgccgc accgcgctgg gcgacggagc ctggatcgac ctgctccccg ggtggctcgg
    15661 cggggcggac gcgctcttcg cccggctcgc ggccgaggtg ccgtggcggg cggagcagcg
    15721 gcagatgtac gagcacacgg tggacgtacc gcggctgctc gcctactacc gcgccggtga
    15781 tctactgccg catccgatcc tggacgaggc acgcgacgcg ctgtccgcgc gctacgccgc
    15841 cgagctcggt gaaccgttca ccacggcagg gctctgctac taccgggacg gccgggacag
    15901 cgtggcctgg cacggtgacc ggatcggcag gggcgcgcgc gaggacacca tggtcgccat
    15961 cctgtcggtc ggcgccccgc gcgatctgct gctgcgcccg cgcgggggcg gcgacaccgt
    16021 gcggcgcccc ctcggacacg gcgacctgat cgtgatgggc ggctcctgcc agcgcacttg
    16081 ggagcactcc atccccaagt cggcgcgggc ggcgggtccg cggatcagca ttcagttccg
    16141 gccgcacggg gtgaactgag tccggccacg ttggggtgcc gtcggtcgcg ctgtcctcgg
    16201 ctcacggcgt gagctgcgcc tgcaccgtcg gggcgtaccg gtcgacgatg tcctcgatcg
    16261 cggtggcgcg caggcgcgtg ccgcgggcga tgccgtacat cacgccgagg ccgagcaggg
    16321 tgctgacggc gagttcggca cgcaggccgg cctgggggcc gctgaggcgc tcggcgaggc
    16381 ggtcgctgac ctgggcgcgg aagttggtgc gcaatatgtc gccctgctcg ccctgaatcg
    16441 gggcgaagac gatccgcagg atgggatcgg cgccgcgctg cgtctggccc tccagcagat
    16501 ggcggaccat gtggcggccg aggtcctcca ccggcgcgtc cagcagagcc tcggcatcgg
    16561 actcgaagga catgacccga gcgaacagcg catccttgtt gccgaagtac ttcaggatca
    16621 gcggcgcgct cacccccgcc cggtcggcga cggccttgag ggtgatgtcc gcgtgggcgt
    16681 gccgggccag cagatggcgg gccgcgagca ggatggccgc cttcgtcgcc tcggcgtcac
    16741 gccgcggtgg ggcggcaggc ggtgtcgtga gtccggggtg cggggtggtc acggtgctca
    16801 tgctccttcg agggcctcgt cacggggcac tccggtgcgc ccgacggccc ctcgggtgtc
    16861 gggcgaggcg gggtcggcgg gtatcgagag ggcagcggcg caagccacca gtgcgaccgt
    16921 acccgccatg gcgaaggcca gcagatagcc gtgcagcgtg ggcagcgggg cgccgccgac
    16981 gaggctcgtg tggtggacca ggacggcggc cacggcggcg ctgcacacgg cctggccgat
    17041 ggtgcgcatc agaacgttga cgccgttggc cgacgcggtc tgtccggcgg gcacggcgcg
    17101 caggatcagg gtgggcaggg cggagtaggc gagggtcgtg ccgatcgcgc agaccgtggc
    17161 ccccaggatg atcagccaca gctcgcggct gtccaggatg cgtatgacat agccgagagc
    17221 gatgatcgcg gtcccgagcg ccagcgtcac gcgggggccg cgggcggccg agatgcgcgc
    17281 cgaaacgggc gaaaggaaca gcatggtgac gccgccgggc agcagacaca ggccggtcgc
    17341 cacgatggac agcccgagcc cgtagccgct ctccttcggc gcctgcacca gctgcgcggt
    17401 caccagggag ttcccgtaga aggcgaagcc cgtcaggagt gcggcgacgt gcggcagggc
    17461 gacccgcggc cgggcggcca acttcaagtc gaccagcggc cgttcggtac gccgctgctg
    17521 tatccaccac agggtcatga tgacgacgca ggccacgaac aggcccagga tccgggggct
    17581 gccccaaccc caggtaccgc cctgagacac ccccagcagc aggcatacga gccccgccgc
    17641 caggcccatc gcgcccactg tgtcgaagcg gcccggctcg cggacgggcg actcgcgcac
    17701 cgcccaccac gccagcgcga ggccgacggc accgagcacc gtcgtcgccc agaacatgac
    17761 gtgccagttg gcgtactgga cgatcagcgc ggcgagcggc aggccgaggg cggcgccaat
    17821 acccacggtg gagctcatca gcgccacggc ggaacccgtg cgctccggag gcagttcgtc
    17881 ccgcaggata ctgatcgaca gcggtacgac ggcggccgcc gcgccctgca gggcccgcgc
    17941 cgcgatgagc acaccgatgt ccgacgtgag ggcgcacagc agcgagccca ccgtcatcag
    18001 cccgagtgcc atcagcagca cgcgccgctt cccgtacatg tcccccgcgc gtcccagcac
    18061 gggcgtgagc accgctccgg acagcagcgt cgccgtcacc atccaggaga ccgcgctcgc
    18121 cgaggcgccc gtcagccgtg gcaggtccgg cagcaacggc accaccacgg tctgcatgac
    18181 agccatgagg atccctccga acgccagaac agggactgcc agccggtcgc gcagggccgc
    18241 catgaatgct ccagaagtcg acatgaaaaa gtgggtgaat gacaattcac cctatcggtg
    18301 aatcatcatt cacccaaagc gccgtcgacc cgtcgccgga cggctaccgg cgggagcggg
    18361 cctgcaccgt gcgggccact cgcggtccca gccagcgctt gaaccgacgc agcggctcca
    18421 gttgccctgc cgcgcggtcg atccggtagt acagctgcgg cgggatgtac gggagcagcg
    18481 gagagtggcg ctgtcccagc agcgcgaaca tctgcgccgg tgggaggcgg atgtagcgcg
    18541 ggaggttctc gtaccactgc gcactgtggc gggccgcgct ctggaccggc agaagtgcgg
    18601 atctgcgggc ccgctcgtat tgagtgaggg cgcattcgag ttccgggtgc tcgcgcagcg
    18661 ctccggccag ggagatggcg tcctccaggg cgagggtggt gcccgcgccg atcgagtagt
    18721 gggtggtgtg cgcggcatcg ccgagcagga cgaggttgcc gcggtgccag gtccggttgg
    18781 tcagggtgcg gaagctgagc cactgcgcgc tgccgtcgac ctgcgcccgg ccgatcagcc
    18841 cgtgaccgtc gagcagatcg gcgaagagtt tttccagcag ggcgagaccg tccgcctcgc
    18901 tcgtccggtc gaggccgagg ccggtccagg tctccgggga gcactcgacg acgcaggtgc
    18961 tgtggtcctc gctgaatccg tagccgtagc accagatcca gccgtggccc gtctccacga
    19021 aggagaaggt gaaggagtcg aagatcttgg tcgtgccgag ccagatgtaa gtgttccgac
    19081 ccagcttgat gtcggtgccg aagtggtcgg cgtggcgctc gcgcagcgcg ctgttgaccc
    19141 cgtcgccggc aatgacgagg tcggcgtcgg gcagccggtc ggccgcgatc tcgtgctcga
    19201 actcgacgcg tacgccgagc gacgtggcac gctcggcgag caggtcgagc atgcggcgac
    19261 ggccgatgcc gaatccctca tcaccgtggt gcaccgtcgt gcggtcgccc acgtgcgcga
    19321 ccccgtcgct ccagcgcacc gagttctcgg cgacggcgag cgcggactcc gggtcgccct
    19381 ctcccagttt ctcgagcaga cccgcccagt aggtcactcc ccagccgtag gtcgatccgg
    19441 ccgggttccg ctcgtagacg gcgatgtcat gggacgggtc ctggcgcttc atcaggatcg
    19501 agaagtacag gcttgcgggt ccgccgccga cgcacgcgat ctccacgcgc actccccttt
    19561 gttacacaaa gcggtcaatt ggtgacgaag cgtagcagtc ggtgtgaccc ctagagttca
    19621 cgtcaccttg cgggcgtgag ccacaccact cgcgacggac cacctcggca agatcatcaa
    19681 cagcgggccg cccaacggga ggaatttcac gttccggtgg gacacgagca ctctcgacag
    19741 caagatcatc ttcgttcaac cttgcactgt atttacttaa ttgtccggat cgcagccaac
    19801 cgacattcgc cgatttctcc cgctctttga tgacccgata ggcataccgg gtcatcaaca
    19861 gaactgatcg caggaggact tcgcatgccg gaactcactc gtcgtcgtgc cctcggggcc
    19921 gcggccgcgc tgaccgtcgt ggtcggcacc caggccctca cggcccccgc tgtgtccgcc
    19981 gcaccgggga tgtcgaccgg cgaacaccac cacggcgggc cggaagcctt cgacgaggtc
    20041 taccgcggcc gccgcataga gggccgcccc gtcagcgggg gcggtcacca ccacggtgcc
    20101 ggatacgccg tgttcgtcga cggcgtggaa ctgcacgtga tgcagaacgc cgacggcagc
    20161 tggatcagtg tcgtcagcca ctacgccccc gtgcccaccc cgcgcgccgc cgcccgtgcc
    20221 gcggtcgtgg agctgcaggg ggccccgctc gtccccttca acgccaactg acccccctcg
    20281 caagcagatc gtggagtccc gcacatgacc gtacgcaaga accaggcgag cctgaccgcc
    20341 gacgagaagc ggcgtttcgt cgacgcgctc gtgcagctca agcgaagtgg ccggtacgac
    20401 gccttcgtca cgacacacaa cgccttcatc atgggcgaca cggacagcgg cgagcgcacg
    20461 ggccaccgtt cgccgtcctt cctgccctgg caccgcagat tcctcatcga gttcgagcag
    20521 gcactgcagt ccgtcgactc aaccgtcgcg ctgccgtact gggactggag cgccgaccgc
    20581 tcgacgcgct cgtccctgtg ggcgcccgac ttcctcggcg gcaccgggcg cagcctggac
    20641 ggccgggtga tcgacggccc gttctcggcc tcgtcgggca actggccgat caacgtgcgc
    20701 gtcgacaacc gtacgtatct gcgcagatcg ctcggcagcg gcgcccggga gctgccgacc
    20761 cgcgccgagg tggagtccgt gctcgccatg gccacgtacg acatggcgcc gtggaacagc
    20821 gcctcggacg gcttccgcaa tcacctcgaa ggctggcgcg gcgtcaatct gcacaaccgg
    20881 gtccacgtct gggtcggcgg gcagatggcc accggcgtct cccccaacga ccccgtcttc
    20941 tggctccacc acgcctacat tgacaagctg tgggccgact ggcagcgccg ccaccccgac
    21001 tcgggctatc tgccgacggc cggtacaccc gacgtcgtcg acctcggcga gacgatgaag
    21061 ccctggaagg acgtacggcc cgcggatctg ctggaccaca ccgcgtacta cacgttcgac
    21121 gccgcctgat cagggccggt caccgccccc gggggccctc gctcgagggg cccccgggac
    21181 ccgaggaaaa gaagctgcgc tcctccgcgc cgatcggcag gatgagtggt gtgctgatca
    21241 tggaacccgt gctggagacc tatgaggccg ccgacttcac gctgtggccc accgccgacc
    21301 agcccgcgga ccggttgctc gtcctgtccg gcgacctgtc gccgctcgag gtcggtaccg
    21361 ccatggccgt cctggccggc tacaacaaga cgcagcgcag gcgtcacgac cccggtcctg
    21421 cggacggcct cgcgatgctg cgccgcctgg tgtcggtcga atccgtcgtc gctccgggcg
    21481 gcttgcggct ccaggactcc gccaccggag tcaccgtgcc gccgggatgc tgcttcggtc
    21541 tggagaactg gcgggactgg cagggtctgc tggacggcga aacgccctgg ctcggccacg
    21601 accccacgcc gggcgtcgag ccatcgggat cgctcgtccg gctgtggccg gacgcggaac
    21661 gcccggccgg actgccgatc gaactggcct tgagcgagct tccggtgctg ctcgaatccg
    21721 tgcgcagcgc gctcaccggg ttcctgggcc tcgtcgaggg gtggacggtc cgggacttcc
    21781 ccgccgcgct cgccgcgcgg gtcgtggcga agctcgacga agacctggcc atgagcggct
    21841 ctctgcgcga agtctcctga cgggggcggc tacgcgttgc tcgtctcggc ggtacggcac
    21901 tccgggtgtc cccacccctg gccgttcttg gcgatcggct cgcccgcggc gtacgagcgg
    21961 ccgcagacgc agcggcccgg gaacttggcc ttgatcgtgc ggctcgacgc gttcggccgc
    22021 gccgcggtct tcgtggagtt gcggcggcgg gcgggtgctg gggagtcggg cgacggcggc
    22081 ggctccgggg atccgaggtc gctgcccgcg ggctgctgga cggtggccgc ctggctcgcg
    22141 gcacggtcgg cgaagtcgtt gaggcggtct ccgtcgacct ggtgcgcggg gacgtagcgg
    22201 aactccactg cgcggccgtc gaggagctcg tcgatgcggg cgaccagttc ctggttggcg
    22261 acgggctttc cggcggccgt cttccagccc ttgcgcttcc agccgggcag ccaggtcgtg
    22321 acggccttca tcgcgtactg ggagtccatc cggatctcca gcggcacgtc cggggcgatc
    22381 gccgtcaaca ggcgttccag cgcggtgagt tcggcgacgt tgttggtcgc cgtgcccagc
    22441 gggccggcct cccagcgggt gggagtctcc tccccgtcgg cgacgaccca ggcccatccg
    22501 gcgggtcccg ggtttccctt cgaagccccg tcacaggcgg ccacaacgcg ttcaggcatg
    22561 gccccgatca tgccacgctc cgcccggagc ccggcgccac gggttcatcg ggccccgcag
    22621 ccggttcacc gggcgccgga ggaactgccc gcgccgagga gtcgcaggcc cagcggagtg
    22681 gccacgtgca ggacgtactt gccctcgcgc cggctggtca cgagtccgcc gtcgcgcagg
    22741 acgccgatct ggtagctggc gctgggcagc gcgatcccca cggccagggc gacctcggag
    22801 gtggtgcggg cggtgcggtt cgccacctcc gtcagtacgg cggccctggt gcggcccagc
    22861 agacgttcga ggccgtcgtc cgtgccgcgc gcgacggcga ggggcgcctt ctcgaccggg
    22921 tagacgagca ccggatcgag gcccgggtcc gccagggcgg tgggccggcg ccagcagaag
    22981 aaggacggca cgaggagcag gccgcggccc tccagataga ggtcgcgctc ggtggggtag
    23041 tccacttcga gcacgggagc ccgccagcga gccagcgggc gcagcccgtc gaggagggcc
    23101 ctggtgccgc cgtcgaggag ggcgcgggaa cgcaggtcga catcgttgcc gacggccgtt
    23161 cctatgtgcg accagtacgg ttccagcagg gcgtggaagt agatcccgag ggctcctgcc
    23221 agggacttga gcgcgtcgct gccgggccgg cccagcgagg tcgtccagct cggcacgggg
    23281 cgcgactcgg ccagccgcgt cagttcacgg accatccgtg cgcggggagt gcgccgcagc
    23341 tggtcgaggc cggcggacag gccgccgccg gtcacgggtg gtgtgaggaa gtccgggatg
    23401 tagccggccg cggggatcag ggcccgcagc gggtgcagcg cgcggcccgc gaccgtgtcc
    23461 tgggacagcc ggtcgtgggc cgcgcgccgc cagtgtccga agtcgagcgg tccctgcccg
    23521 gtttccaacc ggcagacgct gcacatcagc tcccacagcg gatcgggttc ccgggccacg
    23581 cgaatgttct gcagatcgtg cgaggtgaag tgaatgcgaa gcatgcggtc tctttcgctc
    23641 gccgtccttg tgagggatcc ggccaccctg gggtaccgcg gccacaagaa gggacgagca
    23701 tcacatctac gcggttgctc tcgcgaggga acgcctcagg acacgtcggt cgtcttcggc
    23761 atgtctcccc gggtcgtcgt catgtcgatg acggagaacg acgcgccctg cgggtcgctc
    23821 agtgcagcga accggccgaa cgggctgtcc atgggcccga agcgcaggat gccgccgcgc
    23881 tccgtcgcct tcgccaccgc cgcgtcgcag ttctcgacgg tgaagtacac gttgacgtac
    23941 ggcggtacct cgggcgggaa gtcgtccgtc atcttcatcc ggcccagaac gggttcctcg
    24001 cccaggctga agatccggaa gtcgacggca tcgtcctcga cctgcttggc gctgagcggg
    24061 aagacggcgg ggaagaacgc gtcggacttc tcgggctctc gggtgaagac ctcggcccag
    24121 gcgtacgcgc cggggacggc cgtcgcctcg aagccctcgt ggatgcccgc ctgccagaca
    24181 ccgaagacgg cgccgctggg gtcacgggcc agcaccatgg tgccgaactc gccgacctgc
    24241 atcggctcca tcagcacctc accgccgttg tccctgatct tcgtggcggt cgccgcggcg
    24301 tcgggcgagg cgaagtacag gcaccaggcg gactggccct cctgtccggg catcggcggg
    24361 acgacggcgg ccacggcctt gccgttggcg tacgcctgtg tgtagttgcc gtactccgag
    24421 gacgattcgc cgaaagtcca gcccagtacg tcaccgtaga aactcttggc cccctcgaca
    24481 tcgctgaaca tcgcgtccgc ccaacagggc tttccttcag gctgtacggc catggcgtcg
    24541 accttctccg gttcggtgaa cggtgcgcat ttcacgctaa ccaggcttcg ccagggccgc
    24601 gcgccgagtg gggcggcctg caccacactg gagagcgagc acaggtggtc gtcgacagga
    24661 cggggcactg gatgatgatg cacgcgtggg aagtggcccg gcccgggccg atcgacgggg
    24721 atccgctgcg ctacgtcgag aagccggtgc cggtggcggg gcccgacgag ctcctcgtgc
    24781 acgtccgagc gtgcggggtg tgccgcaccg atctgcatgt caccgagggc gacctgcccg
    24841 tgcgccggcc gggggtgacg ccggggcacg aggtcgtcgg cgtcgtcgcg gggaccggcg
    24901 acgacgtgag cggcttcgcc ctcggtgacc gggtgggcgt cgcctggctg cgccgtacgg
    24961 acggcacgtg ccggtactgt ctgcgcggct cggagaatct ctgcccggcg tcccgataca
    25021 ccggctggga cgccgacggt ggttacgcgg agtacacgac cgtcccggcc gcctacgcgt
    25081 accggctgcc cgacgacgtg gacgacatcg ccctggcacc gctgctgtgc gcgggcatca
    25141 tcggctaccg cgcgctgctg agggcctcgc tgccgcccgg cgggcggctc gggctgtacg
    25201 gcttcggcgg cagcgcccac ctgtgcgcgc agctcgccgt cgcgcagggc gccaccgtgc
    25261 acgtcctgac c
//
