LOCUS       NZ_BMMM01000013        21074 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces albiflavescens strain CGMCC 4.7111 sequence13, whole
            genome shotgun sequence.
ACCESSION   NZ_BMMM01000013
VERSION     NZ_BMMM01000013.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces albiflavescens
  ORGANISM  Streptomyces albiflavescens
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 361005)
  AUTHORS   Sun,Q. and Zhou,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 100X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014645835.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 03:24:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,828
            CDSs (total)                      :: 9,745
            Genes (coding)                    :: 9,386
            CDSs (with protein)               :: 9,386
            Genes (RNA)                       :: 83
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 359
            CDSs (without protein)            :: 359
            Pseudo Genes (ambiguous residues) :: 0 of 359
            Pseudo Genes (frameshifted)       :: 102 of 359
            Pseudo Genes (incomplete)         :: 321 of 359
            Pseudo Genes (internal stop)      :: 17 of 359
            Pseudo Genes (multiple problems)  :: 80 of 359
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:54:32
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 166037
            Orig. end                         :: 187111
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMMM01000013.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21074
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21074
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21074
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11074](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11074)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    238..258
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.56"
                     /tool="antismash"
     misc_feature    complement(847..861)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.48"
                     /tool="antismash"
     gene            956..1153
                     /locus_tag="IEY95_RS31490"
                     /old_locus_tag="GCM10011579_063870"
     CDS             956..1153
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY95_RS31490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10011579_063870"
                     /product="hypothetical protein"
                     /protein_id="WP_189189564.1"
                     /transl_table=11
                     /translation="MNIGVCVKHVPTKVTVRQKQPSIAYRSLADRSDIVELSLVSRDGA
                     YEPLVREFLRIAAAGPQPAP"
     gene            1325..2251
                     /locus_tag="IEY95_RS31495"
                     /old_locus_tag="GCM10011579_063880"
     CDS             1325..2251
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018104846.1"
                     /locus_tag="IEY95_RS31495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_063880"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_189189565.1"
                     /transl_table=11
                     /translation="MKQPTHPGTTAPRRRRATSIGAAVGSCALVVASVVSAAPAAADGA
                     GLGRGSRYVSLGDSYTSGPGIPQQVDANCARSDHNYPSLVAAERRATAFKDVSCGGATT
                     EHMWKPQGTNGPQLDALGRDTDLVTVQIGGNDIGFSSIIGTCAQLYATDPTGNPCQRHY
                     SSSGVDQLSLNILETAPKVASVLRAVHGRAPHARVLVVGYPDLLPDDGIGCAPAVPFAA
                     QDFPYLRDTGKRLNLMLRLVAQLNRAEYVDTYGPTRGHDMCKAPEDRWIEPLRPTSPAA
                     PAHPNAKGEEAMARAVLQRLGGGRGHN"
     gene            2658..4547
                     /locus_tag="IEY95_RS31500"
                     /old_locus_tag="GCM10011579_063890"
     CDS             2658..4547
                     /NRPS_PKS="Domain: AMP-binding (65-500). E-value: 1.6e-92.
                     Score: 302.1. Matches aSDomain:
                     nrpspksdomains_IEY95_RS31500_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006376784.1"
                     /locus_tag="IEY95_RS31500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_063890"
                     /product="propionyl-CoA synthetase"
                     /protein_id="WP_189189566.1"
                     /sec_met_domain="AMP-binding (E-value: 4.8e-100, bitscore:
                     329.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGAYEDVFRASVETPERFWLTAAEAIDWDVAPSRALDSSGAPFYR
                     WFPDGRLNVCFNAVDRHIEAGRGEQPALIYDSPVTGTRRTYTYAQLRDEVAAFAGVLAQ
                     LGVGRGDRVVIYMPMVPEAAVAMLACARIGAVHSVVFGGFAPHELAIRIDDAAPKVVVS
                     ASCGIEGKRVIAYKPMLERAIELAVHKPEKCVILQRPQAVAELGPGDLDWAEAVAVAPP
                     ADCVPVPANDPLYILYTSGTTGKPKGVVRDCGGYAVALHWSMGAVYDVGPGETMFTGSD
                     VGWVVGHSYIVYGPLLVGATTVLYEGKPVGTPDAGQFWRVADEYQVKTIFTAPTAFRAI
                     RKEDPKGSLTADYDLSRLRYLFLAGERLDPETYHWASALLNIPVIDHWWQTETGWPIVA
                     NPVGIEAAPVKPGSPTRPLPGWDVRVLDPSGEPVPAGVDGAIVVKLPLPPGSLPTLWND
                     DDRYVASYLSAYDGYYLTGDGGHIDEEGYVFVMGRTDDVINVAGHRLSTGSMEEALAAH
                     PDVAECAVIGVADALKGQVPRGFVVLKAGTGREPHEVEAELVQLVRERIGAVASLKDVA
                     VVAALPKTRSGKILRKTMRGIADGHDEPIPSTVDDPSVIETLRPVLRRAGHTR"
     aSDomain        2853..4157
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEY95_RS31500_AMP-binding.1"
                     /evalue="1.60E-92"
                     /label="IEY95_RS31500_AMP-binding.1"
                     /locus_tag="IEY95_RS31500"
                     /protein_end="500"
                     /protein_start="65"
                     /score="302.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="GRGEQPALIYDSPVTGTRRTYTYAQLRDEVAAFAGVLAQLGVGRG
                     DRVVIYMPMVPEAAVAMLACARIGAVHSVVFGGFAPHELAIRIDDAAPKVVVSASCGIE
                     GKRVIAYKPMLERAIELAVHKPEKCVILQRPQAVAELGPGDLDWAEAVAVAPPADCVPV
                     PANDPLYILYTSGTTGKPKGVVRDCGGYAVALHWSMGAVYDVGPGETMFTGSDVGWVVG
                     HSYIVYGPLLVGATTVLYEGKPVGTPDAGQFWRVADEYQVKTIFTAPTAFRAIRKEDPK
                     GSLTADYDLSRLRYLFLAGERLDPETYHWASALLNIPVIDHWWQTETGWPIVANPVGIE
                     AAPVKPGSPTRPLPGWDVRVLDPSGEPVPAGVDGAIVVKLPLPPGSLPTLWNDDDRYVA
                     SYLSAYDGYYLTGDGGHIDEEGYVFVMGRTDDVINV"
     CDS_motif       2874..2906
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEY95_RS31500_0001"
                     /evalue="1.80E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="IEY95_RS31500"
                     /protein_end="83"
                     /protein_start="72"
                     /score="-0.7"
                     /tool="antismash"
                     /translation="LIYDSPVTGTR"
     CDS_motif       3360..3407
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEY95_RS31500_0002"
                     /evalue="4.90E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="IEY95_RS31500"
                     /protein_end="250"
                     /protein_start="234"
                     /score="25.2"
                     /tool="antismash"
                     /translation="YILYTSGTTGKPKGVV"
     CDS_motif       4128..4184
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEY95_RS31500_0003"
                     /evalue="3.60E-03"
                     /label="NRPS-A_a8"
                     /locus_tag="IEY95_RS31500"
                     /protein_end="509"
                     /protein_start="490"
                     /score="10.2"
                     /tool="antismash"
                     /translation="MGRTDDVINVAGHRLSTGS"
     gene            4747..5211
                     /locus_tag="IEY95_RS31505"
                     /old_locus_tag="GCM10011579_063900"
     CDS             4747..5211
                     /NRPS_PKS="Domain: Polyketide_cyc2 (4-122). E-value: 3e-16.
                     Score: 52.0. Matches aSDomain:
                     nrpspksdomains_IEY95_RS31505_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015655477.1"
                     /locus_tag="IEY95_RS31505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_063900"
                     /product="SRPBCC family protein"
                     /protein_id="WP_189189567.1"
                     /transl_table=11
                     /translation="MEYGSIEREIHVEAAPEVVYEVISTPEHLREWWPDEAELQPVPGG
                     TGVISFGDKSTREAKVVPLTVVEADPPRRFSFRWVYDEGEAATPANSLLVTFELVPSGA
                     GTLLRFTESGFREKGWEAAVLEEQYRDHVTGWDYFLPRLVTYVARLVSTR"
     aSDomain        4759..5112
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEY95_RS31505_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="3.00E-16"
                     /label="IEY95_RS31505_Polyketide_cyc2.1"
                     /locus_tag="IEY95_RS31505"
                     /protein_end="122"
                     /protein_start="4"
                     /score="52.0"
                     /tool="antismash"
                     /translation="SIEREIHVEAAPEVVYEVISTPEHLREWWPDEAELQPVPGGTGVI
                     SFGDKSTREAKVVPLTVVEADPPRRFSFRWVYDEGEAATPANSLLVTFELVPSGAGTLL
                     RFTESGFREKGWEA"
     gene            5208..5546
                     /locus_tag="IEY95_RS31510"
                     /old_locus_tag="GCM10011579_063910"
     CDS             5208..5546
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017236442.1"
                     /locus_tag="IEY95_RS31510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_063910"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_189189568.1"
                     /transl_table=11
                     /translation="MNVTVDDELWSAVGDPIRRRMLDLLLTGGAGTATTLSEQLPVTRQ
                     AVAKHLGVLDRVGLVHVTPSGRERLYQVDEAQLARAVAQLSSVGATWDARLRRIKQIAE
                     AIQRSQEG"
     gene            5636..6076
                     /locus_tag="IEY95_RS31515"
                     /old_locus_tag="GCM10011579_063920"
     CDS             5636..6076
                     /NRPS_PKS="Domain: Polyketide_cyc2 (4-92). E-value:
                     2.9e-09. Score: 29.4. Matches aSDomain:
                     nrpspksdomains_IEY95_RS31515_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015655475.1"
                     /locus_tag="IEY95_RS31515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_063920"
                     /product="SRPBCC domain-containing protein"
                     /protein_id="WP_189189569.1"
                     /transl_table=11
                     /translation="MVDILHRIGVTSSPDAVYAALTTVDGLANWWTEDTDGDGNVGGVL
                     RLCFEPGGFDMKVLEAQPAERVVWEVVDGPEEWIGTQVRFELKQEDGFTIVLFRHEGWK
                     EPVEFMYHCSTKWATFLLSLKKLVETGKGEPAPHDVKISNWH"
     aSDomain        5648..5911
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEY95_RS31515_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="2.90E-09"
                     /label="IEY95_RS31515_Polyketide_cyc2.1"
                     /locus_tag="IEY95_RS31515"
                     /protein_end="92"
                     /protein_start="4"
                     /score="29.4"
                     /tool="antismash"
                     /translation="LHRIGVTSSPDAVYAALTTVDGLANWWTEDTDGDGNVGGVLRLCF
                     EPGGFDMKVLEAQPAERVVWEVVDGPEEWIGTQVRFELKQEDG"
     misc_feature    complement(6102..6116)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     gene            6393..7097
                     /locus_tag="IEY95_RS49395"
                     /old_locus_tag="GCM10011579_063930"
     CDS             6393..7097
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY95_RS49395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10011579_063930"
                     /product="hypothetical protein"
                     /protein_id="WP_229703493.1"
                     /transl_table=11
                     /translation="MSRLSRETFRIGRIRRPSHVRRGAALAALCALALAACGTERAGDR
                     SPKAGLDDRVEAGSPAPSPADSEGAEFLPFMELLVSLAEPCVKDVPAPELPDEPDPAEP
                     PTEPVPELSVPDEPPPTSEPRDPEAAKKEVELSSVEKCEAGIHARRITKALKGTPDPTP
                     RQVREVLRGLGYIDERIHGPQRSDESVEFTLDLRVMGGQLCLSGSAKGTRSVIEPYGAS
                     PEVGCLDVQRHR"
     gene            complement(7224..8168)
                     /locus_tag="IEY95_RS31525"
                     /old_locus_tag="GCM10011579_063940"
     CDS             complement(7224..8168)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014053791.1"
                     /locus_tag="IEY95_RS31525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_063940"
                     /product="DUF5996 family protein"
                     /protein_id="WP_189189732.1"
                     /transl_table=11
                     /translation="MTQQTTHRHEAWPQLRVADWADTRDTLHMWTQIVGKVRLAHAPLI
                     NHWWQVTLYVSPRGLTTSAIPYGSGTFDIEFDFVDHQLCIRTSDGAVRRVALEPKPVAQ
                     FYVETMRALDEVGIEARIQAHPNEVEPAIPFAEDQRHASYDATAARLFWHQLLQAHRVM
                     SVFRSRFTGKVSPVHYFWGAMDLACTRFSGRPAPQHPGGAPNCGDWVMVEGYSRELSSC
                     GFWPGGGEEGAFYAYAYPEPDGFAEYPVTPADAFYSRENGQFLLPYEVVRTAGDPDATL
                     IAFLQTTYEAAAERGRWDRAMLECDPHRLQGFQ"
     gene            8550..9014
                     /locus_tag="IEY95_RS31530"
                     /old_locus_tag="GCM10011579_063950"
     CDS             8550..9014
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006601828.1"
                     /locus_tag="IEY95_RS31530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_063950"
                     /product="VOC family protein"
                     /protein_id="WP_189189570.1"
                     /transl_table=11
                     /translation="MTTPGDLPAPDQGLVLTHFLTVRDVARSSRFYAEILGGEVVLKEN
                     PAIVKVANSWIIMNPGGGPTPDKPGVTLAPPESSDTVSSFLNVRVADIGAFYADAVAKG
                     AEFLTEPLDRKAELRCYMRDPDGYLIEVGQATGMRHGVFADPPAGSQPAV"
     gene            complement(9041..9946)
                     /locus_tag="IEY95_RS31535"
                     /old_locus_tag="GCM10011579_063960"
     CDS             complement(9041..9946)
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016433228.1"
                     /locus_tag="IEY95_RS31535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_063960"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_189189571.1"
                     /transl_table=11
                     /translation="MTIIDGGTTTAPVPTQSTYQNRVADYWNAEENPVNLELGKIDDLY
                     HHHYGVGDVDWSVLDEDDDTGPDDVDSRLTRRRERITAELHRLEQAQADLLARHLGPLS
                     PADRVFDAGCGRGGGSVVAHLRYGCHADGVTISRKQADFAGEQARRRGIDDKVRYHHRD
                     MLDTGFPSGSYAASWNNESTMYVELDLLFAEHARLLRRGGRYVTITGCYNNTYGRASRE
                     VSLINAHYICDIHPRSEYFRALARNRLVPVHVQDLTADTIPYWELRKQADHLVTGIEDT
                     FLTAYGNGSFQYLLIAADRV"
     gene            complement(10001..11074)
                     /locus_tag="IEY95_RS31540"
                     /old_locus_tag="GCM10011579_063970"
     CDS             complement(10001..11074)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020126202.1"
                     /locus_tag="IEY95_RS31540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_063970"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_189189572.1"
                     /sec_met_domain="T1TS (E-value: 1.1e-57, bitscore: 190.7,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAPSTSDSSVTSYGSRLPGPPSLARRARARRGGSIPGLRHRPAV
                     PADPAKAAEVDRRLESWARRLDLFPPAWTEDFSRSQFGRAVVLAHPGAADLERLTSAGK
                     LLVAEHLVDNCYCEMDEDRGGSPHGLGGRLLMAQSALDPYHGTPELENEWQHGVRADGP
                     LRSYHFALRDYAVLATPSQTDRLVHDLARLHLGYLGEAGWADIRYMPRVWEYLVMRQFN
                     NFRPCLAIVDAVDGYELPEAVCVQPEIQRITALAGNAATLVNDLYSFAKELAADPNHLN
                     LPQVIAANERCGLKAAFLKAVEIHNRIMEAFEEESAALSATSPLVGRYAEGLAAWVAGN
                     HEWHATNTHRYHLPDYW"
     gene            complement(11071..12525)
                     /locus_tag="IEY95_RS31545"
                     /old_locus_tag="GCM10011579_063980"
     CDS             complement(11071..12525)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009326604.1"
                     /locus_tag="IEY95_RS31545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_063980"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_189189573.1"
                     /transl_table=11
                     /translation="MSAPEGSSDSSAEPAAGPVAGPTADGQHFTSLSTQAARQLATTTK
                     SEPQMQAITSRWLLKMLPWVDVKGGTYRVNRRLQLRVGRGRVQFEQNGADDIKVIPETL
                     TELPALRGYSDTAALREISQRFRVREVRAGQVLFDAGQPVTEAYLVVHGRFTRYTTGKY
                     GEQEVIGVITDGDGMGDEAIGQADPLWFSSVRAETPGVVLALNWDTLMQFVERTPSLAA
                     QLDAFAEQQNKPMNRKGEADVPVQAGHVGEATLSGGFVDYDLVPREYELSLTQTVLRVH
                     TRVADLYNNPMDQTEQQLRLTIQEIRERQEWELVNNREFGLLHNVDYSQRISTFSGPPT
                     PDDLDELLSMRRKTQLFLAHPKVIAAFFRQCNRRGLVPGTVNVEGHEVPAWRGVPVFPC
                     GKIPISPQHTSSIIALRTGEKDQGAVGLHQTGIPEEYEPGLNVRFMGIDTTAIMNYLVT
                     AYYSMAILVPDAAGILENVQVGWIPE"
     gene            13245..13367
                     /locus_tag="IEY95_RS50230"
     CDS             13245..13367
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY95_RS50230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_268240527.1"
                     /transl_table=11
                     /translation="MPTSSGVLTAGRVQQMGRVGRGKVISAVEAEDRLTANVSI"
     gene            13382..14557
                     /locus_tag="IEY95_RS31550"
                     /old_locus_tag="GCM10011579_063990"
     CDS             13382..14557
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019055979.1"
                     /locus_tag="IEY95_RS31550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_063990"
                     /product="cytochrome P450"
                     /protein_id="WP_189189574.1"
                     /sec_met_domain="p450 (E-value: 2e-21, bitscore: 70.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHRVTAFPLGAATTLAELSRDPHPRLALLRAREPVSWLPELGGW
                     LVTRRDLAVQVMRDAETFTVDDPRFSTAQVVGPSMLSLDGAEHARHRAPFTDPFRPREV
                     LGRFTAFTAKEADRLIDALVPQGAAELRRGFAGPLAVAVMAEALGLAGTATGTVQSWYD
                     AIVDAVTRITAGQAPGPDGAAAYEQLKTAVEHTVGGPDSTSLLASAAGALSLSEVTSNA
                     AVLLFGGLETTEAMIANLLVQLLNDSEQLAAVRGGGPDPLDGAIEESLRLEPGAMVVDR
                     YATRDTTLDSVTVTAGDLVSVSLAGANRDPAVFMDPDRFDIRRGNARLQLAFAHGPHYC
                     VGAHLARLETRVALRRLLERLPGLRLDPGRPRPETRGLVFRKPQAVHVVWG"
     gene            complement(14666..15544)
                     /locus_tag="IEY95_RS31555"
                     /old_locus_tag="GCM10011579_064000"
     CDS             complement(14666..15544)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018557878.1"
                     /locus_tag="IEY95_RS31555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_064000"
                     /product="DMT family transporter"
                     /protein_id="WP_189189575.1"
                     /transl_table=11
                     /translation="MQTTLAVLFALMAAGSNALATVLQRYAARTVPLSVGLRPALIGEL
                     LRKPVWLAGFGAVIVAAAFQALALLNGELSLVQPLFVLELPFALFIGGMVLRRRLPPRG
                     WAAVGSVVAGLGMGLWAASPSAGVDRPRTEVWVMALASCVAAVLLLLAVAVRRPEGRLR
                     AACFGLGAAICYALTAALLKDATQAWNTDGAAAFFTAWQTYGFALVGVAAVFLLENALQ
                     SGPLVASQPALTLGDATVSLSLGVTLFEEELRGGWFALPMLLGALLVVCGALILVRVPL
                     IHTLVAPDAPR"
     misc_feature    complement(15533..15548)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.18"
                     /tool="antismash"
     misc_feature    complement(15656..15672)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.47"
                     /tool="antismash"
     misc_feature    15806..15822
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.47"
                     /tool="antismash"
     gene            16350..16796
                     /locus_tag="IEY95_RS31560"
                     /old_locus_tag="GCM10011579_064010"
     CDS             16350..16796
                     /NRPS_PKS="Domain: Polyketide_cyc2 (3-146). E-value:
                     2.1e-16. Score: 52.5. Matches aSDomain:
                     nrpspksdomains_IEY95_RS31560_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019073573.1"
                     /locus_tag="IEY95_RS31560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_064010"
                     /product="SRPBCC family protein"
                     /protein_id="WP_189189576.1"
                     /transl_table=11
                     /translation="MAGQFEATAEINRPVEEVFAFLADGTNDPKFSPRVQEITKTPEGP
                     TAVGTVFTSTVKDAGMKTGRKFRITEFDAPHRIRWTEISKNIVTADEGGYDLESTGPGT
                     TRVRIFNVLEGHGIGKLLVGFALGAARKDADAFGQRIKAAVEAS"
     aSDomain        16359..16787
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEY95_RS31560_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="2.10E-16"
                     /label="IEY95_RS31560_Polyketide_cyc2.1"
                     /locus_tag="IEY95_RS31560"
                     /protein_end="146"
                     /protein_start="3"
                     /score="52.5"
                     /tool="antismash"
                     /translation="QFEATAEINRPVEEVFAFLADGTNDPKFSPRVQEITKTPEGPTAV
                     GTVFTSTVKDAGMKTGRKFRITEFDAPHRIRWTEISKNIVTADEGGYDLESTGPGTTRV
                     RIFNVLEGHGIGKLLVGFALGAARKDADAFGQRIKAAVE"
     gene            complement(17026..17592)
                     /locus_tag="IEY95_RS31565"
                     /old_locus_tag="GCM10011579_064020"
     CDS             complement(17026..17592)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386676.1"
                     /locus_tag="IEY95_RS31565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_064020"
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="WP_189189577.1"
                     /transl_table=11
                     /translation="MSESALDASEAVTVVFTWEAKPGKEAEFERWAHGIETEAAAFAGH
                     RGVTWLRPEGEAGHGRYHAVVRFADTAALDRWMASPQRAAWQERVRPFGRSVRPKLTTT
                     GLETWFNVPGLPGRPPARWKMSLMTVLAVYPFALLYDGLVAEHFHSWPLPWRTLVFPIF
                     LAPLLTYAVMPRLSRVLRRWLYPQA"
     misc_feature    complement(17619..17635)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.07"
                     /tool="antismash"
     gene            17664..18191
                     /locus_tag="IEY95_RS31570"
                     /old_locus_tag="GCM10011579_064030"
     CDS             17664..18191
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019359222.1"
                     /locus_tag="IEY95_RS31570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_064030"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_189189578.1"
                     /transl_table=11
                     /translation="MSAQSPAPLTERGQVLEERGPGPVAVTLSVNGVERSLEIEPRVSL
                     LDALREHLDLTGAKKGCDQGTCGACTVWVDGHRVLSCLTLAMTCEGREVTTIEGLAEGD
                     ELHAVQQAFIAEDAFQCGYCTPGQIMSAAALLKEGHAGDDAEIKEWMSGNICRCAAYPH
                     IRAAIRAVRDGA"
     gene            18203..19207
                     /locus_tag="IEY95_RS31575"
                     /old_locus_tag="GCM10011579_064040"
     CDS             18203..19207
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016640674.1"
                     /locus_tag="IEY95_RS31575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_064040"
                     /product="xanthine dehydrogenase family protein subunit M"
                     /protein_id="WP_189189579.1"
                     /transl_table=11
                     /translation="MRPITYSRAIDTATAIAAVSADPTSDFLAGGTTEIDLLRQNVLHP
                     RRLVDINDLPLTQIEATPEGGLRIGSLARMSEVAAAPVVRERFPMLSQALELGASAQLR
                     HMASMGGNLLQRVRCSYYRDAESPCNKREPGTGCSAIEGFSRGHAVLGTSEHCIATHPS
                     DAAVALMSLDAQVHTLGPDGGERTYAFDDFFLLPVDSPHREHPMEHGELITAIEVPAAP
                     VARHSLYLKIRDRESYEFALVSVAAALSVVDGIIADVRVSLGGVATKPWRARRVEDFLI
                     GAAAQRSNFAQAARVELIDARATSMNAFKVELAQRAIVRALETLTGDGSESPA"
     misc_feature    complement(19640..19655)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.83"
                     /tool="antismash"
     misc_feature    complement(20222..20236)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.94"
                     /tool="antismash"
     misc_feature    complement(20930..20944)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.91"
                     /tool="antismash"
ORIGIN
        1 gctatgtgct ggtcaccgag gagctggccc gcgggtggat gagcctggcc ggggccatgg
       61 gcgggcacaa cgtggtcgcc aagttgctgc tgcacttcgg taccgaggag cagaagcggc
      121 gctatctgcc gcgaatggcc accggcgagg tccgcgcgac gatggcactg accgaaccgg
      181 gcggcggctc cgacctgcag gcgatgcaca cggtcgcccg ccaggacgcg gacggttatg
      241 tggtcaacgg gacgaagacg tggatcacca actcccgccg ttcgcaactg atcgccctgc
      301 tgtgcaagac ggacaccgag gcgagccccg cgcaccaggg catctccatc ctcttggtcg
      361 agcacggccc ggggctcacg gtctcgcgtg acctgcccaa gctcggctac aagggcgtgg
      421 agagctgcga gttgtccttc gaggactacc gggcgccggc ggacgcggtg ctcggcggtg
      481 tcgagggcaa ggggttcgca cagatgatga ggggcctgga gaccggacgg ctccaggtcg
      541 ccgcccgagc cctgggcgtc ggccgggccg cgttcgagga cgccctcgcc tacgcccagg
      601 agcgcgagtc gttcggcaag ccgatctggc ggcaccagtc catcggcaac tacctcgcgg
      661 agatggccac ttcactcacc gccgcccgcc agctgacgct ctacgcggcc cgagaggcag
      721 aggctgggcg ccgggtggac atggaggcgg gtatggcgaa gctgttcgcc tcggagacgg
      781 ccatgcagat cgccctcaat gccgtccgta ttcatggcgg ttacggctac tccaccgagt
      841 tcgacgtcga acgctacttc cgggacgccc cgttgatgat cgtaggcgag ggcaccaacg
      901 agattcaacg caatgtgatc gcaagccagc ttgtcaggcg cggaggactg gacgcgtgaa
      961 tatcggtgtg tgtgtgaagc acgtgcccac gaaagtgacg gtacgccaga agcagccctc
     1021 catcgcctac cggtccctcg cagaccgctc cgacatcgtg gagctctccc tcgtctcccg
     1081 cgacggtgcg tacgaaccgt tggtgcggga gttcctgcgc atcgcggcag ccgggccgca
     1141 gccggcgcca tgagggtcag ccggccgggg tgaaggcgag acccggacga gcgggagacg
     1201 acggcttcct acctctggtc gcaagaacca actggccggt atacaagcca cgtcgggctt
     1261 gcgcggtcgg accggacctg gctccggccc tgcaagccgc cacggactca gggggaggac
     1321 ctcgatgaag cagcctacgc atccgggcac cacggcgccc aggcgccgac gagcgacctc
     1381 catcggtgcg gcggtcggca gttgtgcgct ggtcgtcgcc tccgtcgttt ccgcggcacc
     1441 cgccgcggcg gacggcgcag gcctcggccg cggttcgcgt tacgtgtccc tgggcgactc
     1501 ctacacctcg gggccgggga tcccgcagca ggtggacgcg aactgcgccc gctccgacca
     1561 caattacccc tcgctggtcg cggcggagcg aagagcgacc gcgttcaagg acgtgagctg
     1621 cggtggagcc accacggagc acatgtggaa gccgcagggc acgaacggcc cgcagctgga
     1681 cgccctgggg cgtgacaccg acctggtgac cgttcagatc ggcggcaacg acatcggttt
     1741 cagctccatc atcggcacgt gcgcccagct ctatgccacg gatccgacgg gaaacccctg
     1801 ccaacgccac tacagctcct ccggggtcga ccagttgagc ctcaacatcc tggaaacggc
     1861 gccgaaggtc gccagtgtgc tccgggccgt gcacggcagg gcaccgcacg cgcgcgtgct
     1921 cgtggtcggc tacccggatc tcctgccgga cgacggcatt ggctgcgccc ccgcggtgcc
     1981 cttcgcagcc caggactttc cctacctgcg cgacacaggc aagcgcctca acctgatgct
     2041 ccgcctggtg gcgcagctga accgggccga gtacgtcgac acgtacgggc ccacccgcgg
     2101 tcacgacatg tgcaaggcgc ccgaggaccg ctggatcgag cccctgcggc caacctcccc
     2161 ggcggctccg gcacacccga atgccaaggg cgaggaagcc atggcgcgtg ctgtgctgca
     2221 acgtctgggc ggcgggcgcg ggcacaactg acagacgccg ccatggtcct cgttccggat
     2281 cggctgacgt accggaggcg agggtccgcc gggggccatg gccgggctga ccagtacttc
     2341 aactgtgaag aataaagagt cgcaacgtgg acggcggccg ggtcagccgg aaacgcgtgc
     2401 cgtcatcctt gccgtcgctc ggcggcactt cctcgaggac ggccatcacg ctgtgacgtt
     2461 gcgttcgatc cggggcagtg ggcttgccca gcgggcccag cagccggctg cgaaggtggg
     2521 tccaaggggg gcggtgcacg gcctcgccgg acacgtgatc gacatgtgag taggctcgtc
     2581 gaagacggcc acgacgtgcg ccgccgcagc aacccggacc ctcgatgcgg cacacgcgat
     2641 gcgacgaagg agagcccatg ggagcgtacg aggatgtctt ccgtgccagt gtcgaaactc
     2701 cggagcgctt ctggctgacg gcggcggaag ccatcgactg ggatgtcgct ccgtctcgcg
     2761 ccctggattc ctcgggtgcg ccgttctacc gctggtttcc cgacgggcgg ctcaacgtgt
     2821 gcttcaacgc ggtcgaccgg cacatcgaag ccggccgggg cgagcagccc gcgctcatct
     2881 acgactcgcc tgtgaccggc acccggcgca cctacaccta cgcgcagctg agggacgagg
     2941 tggcggcctt cgccggagtg ctcgcgcagc ttggtgtggg gcgcggtgac cgggtggtga
     3001 tctacatgcc gatggttccc gaggccgcgg tcgcgatgct ggcctgcgca cggatcggcg
     3061 cggtccactc ggtcgtcttc ggtgggttcg cgccgcacga actcgcgatc cgtatcgacg
     3121 acgccgcccc gaaggtggtc gtctccgcct cctgcggcat cgagggcaag cgtgtcatcg
     3181 cgtacaagcc gatgctggag cgggcgatcg agctcgccgt ccacaagccg gaaaagtgtg
     3241 tgatcctgca acgcccgcag gcggtggccg agttggggcc cggcgatctc gactgggccg
     3301 aggcggtcgc tgtggcgcca ccggccgact gcgttcccgt cccggcgaat gatccgctgt
     3361 acatcctcta cacgtccgga acgaccggga aacccaaggg cgttgtgcgg gactgcggcg
     3421 gctacgcggt ggccctgcac tggtcgatgg gagccgtcta cgacgtgggc ccgggcgaga
     3481 cgatgttcac cggttccgat gtcggctggg tcgtcgggca ttcgtacatc gtctacgggc
     3541 cgctgctggt cggcgcgacg acggtcctgt acgagggcaa gccggtcggc accccggacg
     3601 cgggccagtt ctggcgcgtc gccgacgagt accaggtcaa gaccattttc acggcaccca
     3661 cggccttccg cgccatccgc aaagaagacc cgaaggggtc gctcaccgcg gactacgacc
     3721 tctcccggct gcgctacctc ttcctcgccg gtgagcgcct cgaccccgag acgtatcact
     3781 gggcgagcgc gctcctgaac atcccggtga tcgaccactg gtggcagacc gagaccggct
     3841 ggcccatcgt cgccaacccg gtcggtatcg aagccgctcc cgtcaaaccc ggctccccga
     3901 cccgtccgct gcccggctgg gacgtccgcg tccttgaccc ctcgggcgag ccggtgcccg
     3961 cgggcgtcga cggcgccatc gtcgtgaagc tccccctgcc gcccggttcg ctccccacgc
     4021 tctggaacga cgacgaccgc tacgtcgcct cctatctctc cgcctacgac ggctactacc
     4081 tcaccggcga cggcggccat atcgacgaag agggctacgt cttcgtcatg ggccgcaccg
     4141 acgacgtcat caacgtcgcc ggacaccgcc tgtccaccgg cagcatggaa gaggccctgg
     4201 ccgcccatcc cgacgtcgcc gaatgcgccg tcatcggcgt ggcggacgcg ctgaagggac
     4261 aggtgccgcg gggcttcgtc gtcctgaagg cgggcaccgg ccgcgaaccg cacgaggtcg
     4321 aggccgaact cgtccaactc gtacgtgagc gcatcggcgc tgtcgcctca ctgaaggacg
     4381 tcgcggtcgt ggccgccctg cccaagacac gctcgggaaa gatcctgcgc aagacgatgc
     4441 gcggcatcgc cgacggccac gacgaaccca tcccctccac agtggacgac cccagcgtca
     4501 tcgagaccct gcgccccgtt ctccgccgcg cgggccacac ccgttgaagg cagcctgagc
     4561 cgttacgggg agggcggcct cgccaggacg tccggctgtg tcgagctgcg gcgtgtcatg
     4621 tgcggctcgc gcggcaacct cgcctgtgac atcagtcgat tcttagagca accaatggtt
     4681 gcgcatgctg ggggagtgcc ctaaagtcat gtgcaaccaa aggttgcgag aggatggagg
     4741 ggcgggatgg agtacggcag catcgagcgg gagatccacg tcgaagccgc gcccgaggtg
     4801 gtctacgagg tcatcagcac gcccgagcac ctgcgggagt ggtggccgga cgaggcggaa
     4861 ctgcagccgg tgcccggcgg caccggagtc atctcgttcg gcgacaagtc gacgcgggaa
     4921 gcgaaggtcg tacccctcac ggtggtggag gccgacccgc cccggaggtt ctccttccgg
     4981 tgggtgtacg acgagggtga ggccgcgacg ccggccaact cgctcctggt gaccttcgag
     5041 ctggtcccct cgggtgcggg cacgctgctg cggttcaccg agtcggggtt ccgggagaag
     5101 ggctgggagg cggccgtgct cgaggagcag taccgcgacc acgtcaccgg ctgggactac
     5161 ttcctgcccc gcctcgtcac gtatgtcgct cggctggtgt cgacgcgatg aacgtcaccg
     5221 tcgacgacga gctctggtcg gcggtggggg accccatccg gcggcggatg ctcgacctgc
     5281 tgttgaccgg tggcgccggg accgcgacca cgctgagtga gcagctgccg gtcacgcggc
     5341 aggcggtcgc caaacacctt ggcgtgctcg accgggtcgg gctcgtccac gtcacgccgt
     5401 ccggacgcga gcgcctctac caggtggacg aggcccaact cgcccgcgcg gtcgcgcagc
     5461 tgtcgtcggt cggagccacc tgggacgccc ggctgcgtcg catcaagcag atcgccgagg
     5521 caatccagcg cagccaggag ggctgacccc cttacggacg aacgtcgcca catccgaggc
     5581 ggcgctgatg caccgcgccc gcatgcgggc gcctgcacga gaaagaggta tcgagatggt
     5641 ggacatcctg cacaggatcg gagtcacgtc gtcccccgac gctgtctacg cggccttgac
     5701 cacggtcgat gggctggcga actggtggac ggaggacacg gacggtgacg gcaatgtcgg
     5761 gggagtgctc cggctctgct tcgagcccgg cgggttcgac atgaaggtcc tggaggctca
     5821 gccggccgag cgcgtggtct gggaggtcgt cgacggcccc gaggagtgga tcggcacgca
     5881 ggttcgcttc gagctcaagc aggaggacgg cttcacgatc gtgttgttcc ggcacgaagg
     5941 ctggaaggag cccgtggagt tcatgtacca ctgcagcacc aagtgggcga ccttcctgtt
     6001 gagcctcaag aagctggtcg aaacgggcaa gggcgagccc gcgccgcacg acgtcaagat
     6061 cagcaactgg cactagacgc cgatcctcag cgagcaggcg ctggccgagt cggtcgccaa
     6121 ccccgcgctg aagccgttga agtgtcacgc gcctgaggct cgttgacggc ttactgcgac
     6181 ggtgcggcgg tgcggcgatg cggcggtgcg gcggtgcggc gggtgcaggc cagtcgtacg
     6241 tctgggtgag ctggttgacc agcgctccgc gcgaggcgga agtgccgtca tgggcacctg
     6301 ctcctgccag gagtttccgg gtgagtacgc ggggtctggc tctgagtagc ggtactcatg
     6361 cccggtccgc tgctcacgcc cacactgcga acatgagccg actttccagg gaaacctttc
     6421 gaatcggtcg catacggcga ccctcccatg tccggcgtgg cgcggcgctg gcggcgttgt
     6481 gcgcgctagc cctcgccgcc tgcggcacag aacgagcggg cgacaggagc ccgaaggcgg
     6541 gactcgacga ccgggtcgag gccggctcgc ccgcaccctc cccggccgat tccgagggcg
     6601 ccgagttcct cccgttcatg gaacttctcg tatccctcgc cgagccgtgt gtgaaggacg
     6661 tcccggcccc ggagctgccg gacgagccgg atccggcgga gccgcccacc gaacccgtgc
     6721 ccgagttgtc cgtccccgac gagccgccac ccacaagtga accccgggac cctgaggccg
     6781 ccaagaagga ggtggaactg agctccgtgg agaagtgcga ggccggtatc cacgcccgtc
     6841 gcatcacgaa ggccctcaag ggcacgcccg atccgacgcc gcggcaggtc agggaggtcc
     6901 tgcgcggcct cggctacatc gacgagcgga tccacggccc gcaacgctcc gatgagagcg
     6961 tggagttcac cctcgacctg cgggtgatgg gcggccagct gtgtctgtcc ggcagcgcca
     7021 aaggcacgcg gtccgtgatc gagccgtacg gcgcttctcc tgaggtcggc tgcctggatg
     7081 tgcagcgtca ccgctgaaca gaggcagaca ggccgagccg tccctgacac ggccgtcacc
     7141 ctcttcgagc ggaccacgac gatcagccgg gtgtcagcgt caatgaccaa ccgccgtcaa
     7201 ggagcccacc gggcgagtcg ccgtcattgg aagccctgca agcgatgggg gtcgcactcg
     7261 agcatggcgc ggtcccaccg tccgcgttcg gctgccgcct cgtaggtggt ctgaaggaac
     7321 gcgatgagcg tggcatccgg gtcaccggcg gtgcgaacga cctcgtacgg caggaggaac
     7381 tggccgtttt ccctgctgta gaaggcatca gccggagtga cagggtattc ggcgaagcca
     7441 tcgggctccg ggtaggcata ggcgtagaag gctccttcct cgccgccgcc gggccagaag
     7501 ccgcaactgc tcagctcgcg ggaatagcct tccaccatca cccagtcacc gcagttgggt
     7561 gcgccgccag gatgctgtgg ggcggggcgg ccggagaacc tcgtgcatgc caggtccatg
     7621 gctccccaga agtagtgcac cgggcttacc ttgccggtga agcgtgagcg gaaaacgctc
     7681 atgacgcgat gggcttgcag cagttgatgc cagaagaggc gggccgcggt ggcgtcgtag
     7741 gaggcgtggc gctgatcctc ggcgaacggg atcgccggtt ccacttcgtt cgggtgggcc
     7801 tggatccgcg cctcgattcc cacctcgtcc agggcgcgca tcgtctcgac gtagaactgg
     7861 gccactggct tgggctccag ggccactctg cggacggcac cgtcgctggt acggatgcac
     7921 agctggtggt cgacgaagtc gaactcgata tcgaaggttc cggacccgta cgggatggcg
     7981 gaagtggtca gcccgcgtgg actgacgtac agcgtgacct gccaccagtg gtttatcagc
     8041 ggtgcgtgcg ccaggcgcac tttgccgacg atctgggtcc acatgtgcag ggtgtctctt
     8101 gtgtcggccc agtcggccac ccgtagctgt ggccaggctt cgtgcctgtg cgttgtctgc
     8161 tgtgtcaccg ttgtgccttc cggatcggcg tcatcggtgt tcgggacgga ggcagactcg
     8221 gccggtggga agggccgatc ggctgcacaa gctcccgggg gcacacgctc ctggccgctg
     8281 ccggggacgg attcccttct aagcaggctc acctccacgc gccgcatggg caactcgaac
     8341 ggctgcacgg ccaccggcgc agtcgggcac cggcgagacg cactcctgac ctgggtaaac
     8401 ggcgaccatg cgtgccacgc cggccgcata ttccatgatc aagctgctta ttcccggacc
     8461 aagcgggaac cctggctgag ccggtccggg cacgagaggt gggcccggcg cgcggcctgg
     8521 ctctgcaccc gcacgagagg gttatgacga tgacgactcc tggtgatctg cccgcacctg
     8581 accaagggct tgttctcacc cacttcctga ccgtgcgcga cgtggcgaga tcgagtcgct
     8641 tctacgcaga gatcctcggc ggtgaggtcg tgctgaagga gaacccggcc atcgtgaaag
     8701 tggccaacag ctggatcatc atgaacccag gaggcggacc caccccggac aagcccggcg
     8761 tgaccctggc accgccggag agcagcgaca ccgtttccag cttcctgaac gtccgtgtcg
     8821 ccgacatcgg cgccttctac gccgacgccg tggccaaggg cgcggagttc ctcacggagc
     8881 ctctcgaccg gaaggccgag ctgcgctgct acatgcgtga ccccgacggc tacctcatcg
     8941 aggtcggcca ggccaccggc atgcgccacg gcgtgttcgc cgacccaccc gccggatcgc
     9001 aacctgcggt gtgacccgcc ggccccggcg tgcagtggag tcagacgcgg tcggctgcga
     9061 tcagcaagta ctggaagctg ccgttcccgt aggcggtcag gaaggtgtcc tcgatgcctg
     9121 tgaccaggtg gtcggcctgc ttgcgcaact cccagtaagg gatggtgtcg gcggtcaggt
     9181 cctgtacatg gacggggacg aggcggttgc gggccagggc gcggaagtac tccgaccgtg
     9241 ggtggatgtc gcagatgtag tgggcgttga tgagggacac ctcacgggag gcccgtccgt
     9301 aggtgttgtt gtagcaaccg gtgatcgtca cgtagcgtcc gccgcggcgc aacagccggg
     9361 cgtgttcggc gaacagcagg tccagctcca cgtacatggt ggactcgttg ttccaggaag
     9421 ccgcgtacga gccggaggga aagccggtgt cgagcatgtc gcggtggtgg tagcgcacct
     9481 tgtcgtcgat gccacgcctg cgggcctgct cgcctgcgaa gtcggcctgt ttccgggaga
     9541 tcgtgacgcc gtcggcgtgg cagccgtacc gcagatgggc caccacgctg ccgccgccgc
     9601 gtccgcagcc cgcgtcgaag acgcgatcgg cgggggagag ggggccgagg tggcgggcga
     9661 gcaggtcggc ctgggcctgc tcgaggcggt gcagctcggc ggtgatccgc tcccggcgcc
     9721 gggtgagtct ggagtcgaca tcgtccgggc cggtgtcgtc gtcctcgtcg agcacggacc
     9781 agtcgacgtc tccgacgccg tagtggtggt ggtacaggtc gtcgatcttt ccgagttcga
     9841 ggttgaccgg gttctcctcg gcgttccagt agtccgcgac gcggttctgg tacgtggact
     9901 gggtcggcac cggtgctgtc gtggtgccgc cgtcgatgat ggtcaatggt gactcctcgt
     9961 ggtgcggtcg gcgatgggca tgtcgatggg cgctcggtga tcaccagtag tcgggcaggt
    10021 ggtagcggtg ggtgttggtg gcatgccact cgtggttgcc ggccacccag gcggccaggc
    10081 cttcggcgta gcgcccgacc agcggtgagg tggcggacag ggccgcggat tcctcctcga
    10141 acgcctccat gatccggttg tggatctcga cggccttcag aaaggcggct ttcagcccgc
    10201 accgctcgtt cgcggcgatg acctggggca ggttgagatg gttcggatcg gcggccagtt
    10261 ccttggcgaa ggagtacagg tcattgacga gggtggcggc gttgccggcg agggcggtga
    10321 tccgctggat ctcgggctgt acgcagaccg cctcgggcag ctcgtagccg tccacggcgt
    10381 cgacgatcgc cagacaggga cggaagttgt tgaactggcg catcaccagg tactcccaca
    10441 cccgcggcat gtaccggatg tcggcccagc cggcctcgcc gagatagccc agatgcagcc
    10501 gggccaggtc gtgcacgagc cggtcggtct ggctgggcgt ggcgaggacg gcgtagtccc
    10561 gtagcgcgaa gtggtacgag cgcagcggcc cgtcggcccg cacgccgtgt tgccactcgt
    10621 tctccagctc gggggtgccg tggtacggat cgagcgccga ctgggccatg agcagccggc
    10681 cgcccagtcc gtgcggtgat ccgcccctgt cctcgtccat ctcgcagtag cagttgtcga
    10741 cgaggtgctc ggcgaccagc aacttgccgg cggaggtaag gcgttcgagg tcggcggcgc
    10801 ccggatgcgc gagcacgacg gctcgcccga actgggacct cgagaagtcc tcagtccacg
    10861 cgggcgggaa cagatcgagg cgacgggccc aggactccag cctgcggtcg acctcggcgg
    10921 ccttcgcggg gtcggcgggg acggcgggcc ggtgccgcag cccgggtatg gaaccgcctc
    10981 gccgggcccg cgccctacgg gccaggctcg gcgggccggg cagccgcgat ccataggacg
    11041 tcacggacga atcggatgtc gacggtgcgt tcattccggg atccacccga cctgtacgtt
    11101 ctccaggatc cccgcggcgt cgggcacgag gatggccatc gagtagtagg cggtgaccag
    11161 gtagttcatg atcgctgtgg tgtcgatgcc catgaaccgt acgttcagac caggctcgta
    11221 ctcctcgggg ataccggtct ggtggaggcc taccgctcct tggtccttct ctccggtgcg
    11281 cagcgcgatg atgctgctgg tgtgctgcgg actgatcggg atcttgccgc agggaaagac
    11341 cggaacgcca cgccaggcgg gcacttcgtg cccctcgacg ttcacggtgc cgggcacgag
    11401 gccgcgccgg ttgcactgcc ggaagaaggc cgcgatcacc ttcggatgag ccaggaacag
    11461 ctgggtcttg cggcgcatcg acagcagttc gtcgaggtcg tccggtgtgg ggggaccgga
    11521 gaaggtgctg atgcgctggc tgtagtccac gttgtgcagc agcccgaact cgcggttgtt
    11581 gaccagctcc cactcctggc gttcgcggat ctcctggatg gtcaggcgga gttgctgttc
    11641 ggtctggtcc atcgggttgt tgtagaggtc ggcgacccga gtgtggaccc gcagcacggt
    11701 ctgggtgaga gagagctcgt actcgcgcgg caccaggtcg tagtcgacga agccgccgga
    11761 gagggttgcc tcgcccacgt gcccggcctg cacggggacg tcggcctcgc ccttgcggtt
    11821 catgggcttg ttctgctgct ccgcgaaggc gtccagctgg gccgcgaggg acggggtgcg
    11881 ctcgacgaac tgcatcaggg tgtcccagtt gagcgccagc accactcctg gcgtctcggc
    11941 ccgtaccgag ctgaaccaca gcgggtcggc ctggccgatg gcctcgtctc ccattccgtc
    12001 gccgtcggtg atgactccga tgacctcttg ctcgccgtac ttgccggtgg tgtagcgggt
    12061 gaaccggcca tggacgacga gataggcctc cgtgacgggc tgcccggcgt cgaagaggac
    12121 ctggccggcg cgtacctccc gtacccggaa ccgctgggat atctccctca gggcagcggt
    12181 gtcggagtag ccgcgcaggg ccggcagctc ggtgagcgtc tcggggatga ccttgatgtc
    12241 gtcggcgccg ttctgctcga actgcacccg gccgcggccg acgcgcagtt gaaggcggcg
    12301 gttgacccgg taggtgccgc ccttgacgtc cacccacggg agcattttga gcagccatcg
    12361 ggaggtgatg gcctgcatct gcggttcgga cttggtggtc gtggcgagct gacgcgccgc
    12421 ctgcgtgctg agactggtga agtgttgtcc gtcggcggtg ggtcctgcga cgggtccggc
    12481 agcgggttct gcggagctgt cggaggagcc ttccggtgct gacacattcc ctcccgatac
    12541 gtgagcggac gttggcgggc acgagcgaac aggggcggac acggccggag cggtcgcgac
    12601 gagcgagtcc gtcgtccgtg agtgagcgcg ccggcttcct ccagtggacg tcgacgacgt
    12661 ggaacgcgga gggggcgcgc ctacgacttg gccgcagacg agacgtgctg cgttctgttg
    12721 ccgcaggcga gccgactgcg gcgcgttcaa gggctgtcag ggggttacgg cgctccgagc
    12781 agacgggaac cccgggattg ccgaggcgat gcgcgggcgg ccgagggggg tgggttcacg
    12841 gaggcggtgg cggtcgagga cgggttacgg ggagatggac gccatgacag caacctagtg
    12901 acggtgcgtg cggctgagct gcgcgcgctg tcagtagaac caaacagcct cggatggcgg
    12961 tcgggaaccg cgtgaaaggg gcgtgttcgt gactcggagg tgcagatcca ccgagcgagg
    13021 cagaccatga gcggggaggt gcgcccacgc cggtcgactg cctctgccac cggagcagag
    13081 ggcgtaggga gcttccgaga aggacgggcg cggccgcacg tcccggttgc ccttcggtcc
    13141 ggccggcatt gtcgcgtacg tacggcggtc cccgcggtgc cttcgggtga cgtcctgctg
    13201 accggcttcg ccggtggacg tcgcccgccg cgtcgaccac gccgatgccc acgtcgagcg
    13261 gcgtcttgac ggcggggcgg gtgcagcaga tgggcagggt gggtaggggc aaggtcatct
    13321 ccgcggtgga ggccgaggac cggctgaccg ccaacgtttc gatctgagga tgggggctgg
    13381 gatgacgcac cgcgtcaccg cctttccgct gggcgcggcg acgacgctcg ccgagctgag
    13441 ccgtgacccg catccgcggc tggcgctact gcgcgcccga gagccggtct cttggctgcc
    13501 cgagctgggc ggctggctgg tcacccggcg cgacctggcg gtgcaggtga tgcgggacgc
    13561 ggagaccttc accgtggacg acccccgctt ttccaccgcg caggtggtcg gcccgagcat
    13621 gctgtcgctc gacggcgccg aacatgcccg gcaccgggcg ccgttcaccg accccttccg
    13681 gccccgagag gtgctgggcc ggttcacggc gttcacggcg aaggaggcgg accgactgat
    13741 cgacgccctg gtcccgcagg gggcggcgga attgcgaagg ggcttcgcgg ggccgctcgc
    13801 cgtcgccgtc atggcggagg cgctcggtct cgccggaacc gccaccggca ccgtacagag
    13861 ctggtacgac gccatcgtgg acgccgtcac ccggatcacg gcggggcagg cgcccggccc
    13921 ggacggggcc gccgcgtacg aacagctgaa gacggcggtg gagcacaccg tcggcggccc
    13981 ggacagcacg tcgctgctgg catcggcggc cggggcgctg agcctgtccg aggtgacgtc
    14041 caacgcggcg gtactgctgt tcgggggcct ggagacgacg gaggcgatga tcgccaacct
    14101 ccttgtccag ctgctcaacg actccgagca gctggccgcg gtccgcggcg gcggtccgga
    14161 tccgctcgac ggcgccatcg aggagtccct gcgcctggag cccggcgcga tggtggtgga
    14221 ccgatacgcc acccgggaca ccaccctcga ctcggtgacc gtgaccgccg gggacctggt
    14281 cagcgtgtcg ctggccggcg ccaaccgtga cccggcggtc ttcatggatc cggacaggtt
    14341 cgacatacgg cggggcaacg cgcgcctgca gctggccttc gcccacggtc cgcactactg
    14401 cgtgggcgcg catctggcac gcctggagac acgcgttgcc cttcggcggc tgttggagcg
    14461 cctgccgggg cttcggctcg acccgggccg cccgaggcca gagacaaggg ggctggtgtt
    14521 tcgcaagccg caggccgttc acgttgtctg gggctgacgc ccgcggttcc tcgcaggaat
    14581 cacgctgaac gccgacccat cgcagaagag acgggatcgg ctgtttccgg cctgacggcc
    14641 gggtctgagg ccaagactct ggtgatcagc ggggggcgtc cggcgccacc agcgtgtgga
    14701 tcagcgggac gcggacgaga atcagcgcgc cgcacacgac gagaagcgcg cccagcagca
    14761 tgggcagtgc gaaccaaccg ccccgcaact cctcctcgaa gagggtgaca cccagactga
    14821 ggctcaccgt cgcgtccccc aaagtcagcg ccggctgaga ggccaccagg ggccccgact
    14881 gcaacgcatt ctccagcagg aagacggcgg caaccccgac gagcgcgaag ccgtacgtct
    14941 gccaggcggt gaagaaggcg gccgcgccgt cggtgttcca cgcctgcgtg gcgtccttca
    15001 gcagcgccgc ggtcagcgcg tagcagatgg ccgcccccag accgaaacag gcggcgcgca
    15061 gccgtccctc cgggcgccgc acggcgaccg cgagcagaag cagcacggcc gctacgcaac
    15121 tggccagcgc catcacccac acctccgtac gcggccggtc caccccggca ctgggggagg
    15181 ccgcccacag ccccatgccc agccccgcca ccacgctgcc caccgcggcc cagccgcgcg
    15241 gtggcagccg ccggcgcagc accatgccgc cgatgaacag cgcgaagggc agttccagga
    15301 cgaacagcgg ctggacgagg gagagctcgc cgttgagcag ggccagggcc tggaaggcgg
    15361 ccgccacgat caccgccccg aagcctgcga gccacaccgg cttgcgcagc agctccccga
    15421 tgagggccgg ccgcagcccc acggacaggg gcaccgtccg ggccgcgtac cgctgcagaa
    15481 ccgtggccag ggcgttgctg cccgccgcca tcagggcgaa cagcacggca agggtggtct
    15541 gcaccaggaa tctcctccct ctcgtgccgc acggtacttg atcgactcgc caccgttccg
    15601 gagacgtggc gagtgcgtct gccgccctcg aagaccgacc gtctgccgct aggccctgtc
    15661 gtcaaattcc cgtctgcccc gcgacgccat gcacgcactc tcgccgcacc gggcacagac
    15721 ccaagtacat ccagtacgag ggcctgtgcc cggcacgccg agagcacgca cctgacgccg
    15781 cagggcccgc cctccgggcg gacgacggga atttgacgac aggacctagg cccgcccggg
    15841 gacggcgacc gcactgggat cgaacgcaca caaccacctg aggagcccat cgctcctggt
    15901 gaggggggat ggatgccgcg tggcggatgc cggcggccca gtgcagggcg agcacggctg
    15961 agcacgctga acgagcacgt tgagcaaggg ctcttcgggt gtctcggctt gacccgcccc
    16021 cgcgagggcg gcgggccacc aaggcggggc cgtcacgccg ggtagacgaa gtgctgggcg
    16081 gcgcaggggt gttggtgtcg aacagcgcgc acgcgggcgc ttctggtggt gtcagctgcg
    16141 cccgatgctc cgcttctgcg cggtccgtgt ccgggctgcc gcgcttcccg cggaccgtgc
    16201 accaggcacg gcatgcgtga ggcgggttcg cctctcggcc ttctccagcg cgaggacgcg
    16261 ctgctggggc cgggcccgta ggctgagggc gcttggcaca cgcgcgtgca ctcagtcgga
    16321 gctccagcga tcgcagcaca ggaggaaccg tggccggtca gttcgaggcg acagccgaga
    16381 tcaaccgccc tgtcgaggag gtgttcgcct tcctcgccga cggcacgaac gaccccaagt
    16441 tcagccccag ggtgcaggag atcacaaaaa cgccggaggg tcccacggcg gtgggcacgg
    16501 tcttcacgag cacggtcaag gacgccggca tgaaaacggg ccggaagttc cggatcaccg
    16561 agttcgatgc gccccaccgg atccgctgga cggaaatctc gaagaacatc gtgacggcgg
    16621 acgagggtgg ctacgacctg gagtccaccg gtccgggcac gacccgcgtg aggatcttca
    16681 acgtcctcga aggccatggc atcggcaagc tcctcgtagg cttcgcgctg ggtgcggcac
    16741 gtaaggatgc ggacgcgttc gggcagcgga tcaaggcggc tgtggaggcg tcctgagggg
    16801 gctggacctc actcggtaat ccgctgaccg ggcatacgcc tggagcacga cagcggtcgg
    16861 ctccgcctgc ggccttcgcc atggcggacc aggcttcgca gcagaccgct gagctgctcg
    16921 aagactctgt cctctggtcg gcaggcgaaa tatcgggggc cgcgtccggt gagcgaccgg
    16981 cggtgccagc acggcaaagt cagctccgga cttgcccgac cgcggctatg cctggggata
    17041 gagccaccgc cgcagcaccc tgctgagccg gggcatgacc gcgtaggtga ggagaggcgc
    17101 gaggaagatc gggaagacca gcgtccgcca gggcagtggc cagctgtgga agtgctcggc
    17161 gaccagcccg tcgtacagca gggcgaacgg atagaccgcg aggaccgtca tcagcgacat
    17221 cttccaccgg gccggaggcc tccccggcag gccggggacg ttgaaccagg tctccaggcc
    17281 ggtggtggtc agtttgggcc gcaccgaccg gccgaagggc ctgacgcgct cctgccaggc
    17341 ggctctctgc ggcgaggcca tccagcggtc cagggccgcg gtgtccgcga aacggaccac
    17401 cgcgtggtaa cgcccatgcc cagcctcccc ttcgggtcgc agccaggtga cgccccgatg
    17461 gccggcgaag gccgctgcct ccgtctcgat cccgtgggcc caccgctcga actccgcttc
    17521 cttgccgggc ttcgcctccc aggtgaagac cacggtcacc gcctcactgg cgtccagcgc
    17581 gctctcgctc atgccgaaat cctacggttg cagggcatat gtgcctgtat gacgattgag
    17641 gggtctctct ctggaggtgg cccatgtctg cacagagtcc ggctcccctc accgagcgtg
    17701 ggcaagtcct cgaagagcga gggccgggcc cggtcgcggt caccttgtca gtcaacggcg
    17761 tggaacgctc cctggagatc gagccgcgcg tcagcctgct cgacgcgctg cgcgagcacc
    17821 tggacctgac cggtgcgaag aagggctgcg accagggcac gtgcggtgcc tgcaccgtgt
    17881 gggtggacgg ccatcgtgtg ctgtcctgcc tcacgctcgc catgacctgc gaggggcgcg
    17941 aggtgaccac catcgaggga ctggcggagg gcgacgaact gcacgccgta caacaggcgt
    18001 tcatcgctga ggacgccttc cagtgcggct actgcactcc tggtcagatc atgtcggccg
    18061 ccgcgctgct gaaggagggc catgccggcg acgacgccga gatcaaggag tggatgagcg
    18121 gcaacatctg ccgctgcgcc gcctaccccc acatccgggc cgcgattcgc gcagtccgcg
    18181 acggagccta gggagccttg ccgtgcggcc gatcacctac tcgcgcgcca tcgacaccgc
    18241 gacggcgatc gccgcggtca gcgccgaccc caccagcgac ttcctcgccg gcggcaccac
    18301 cgagatcgat ctgctccggc agaacgtcct ccatccgcgg cggctcgtcg acatcaacga
    18361 cctgcccctg acacagatcg aggccacccc ggagggaggt ctgcgcatcg gctccctggc
    18421 ccggatgagc gaggtcgctg cggcacccgt ggtgcgcgag cgcttcccga tgctcagcca
    18481 ggccctggag ctaggcgcct cggcacagct tcggcacatg gcgtccatgg gcggcaacct
    18541 cctgcagcgg gtgcggtgtt cgtactaccg ggacgcggag tccccgtgca acaagcgtga
    18601 gccgggcacc ggttgctctg ccatcgaggg gttcagccgc gggcacgccg tccttggcac
    18661 cagcgagcat tgcatcgcca cccacccctc ggacgcggcc gtggcgctga tgtccctcga
    18721 cgcacaagtg cacacactgg gccccgacgg cggcgaacgc acgtatgcct tcgacgactt
    18781 cttccttctg cccgtcgact ccccgcaccg cgagcacccg atggagcacg gcgaactgat
    18841 cacggccatc gaggtgcccg cggcgcccgt ggcccgccac tcgctctatc tgaagatccg
    18901 ggaccgcgag agttacgagt tcgcgctcgt ctccgtggcg gccgcgttgt ccgtcgtgga
    18961 cggcatcatc gcggacgtgc gggtgtcgct cggaggtgtc gccaccaaac cgtggcgggc
    19021 ccggcgggtc gaggacttcc tgatcggcgc cgccgcgcag cggagcaact tcgcccaggc
    19081 ggcccgggtg gagctgatcg acgcccgggc gacctccatg aacgctttca aggtcgaact
    19141 cgcccagcgc gcgatcgtgc gcgccctcga aaccctcacc ggcgacggaa gcgagagccc
    19201 ggcatgacga ccgcaccggc aatcggacag cccctcgacc gtgtcgacgg ccgccccaag
    19261 gtcaccggca ccgcccgcta ctccgccgag atcccgatcc ccggcacggc ctacgcctgc
    19321 ctcgtcggct ctcgcgtcgc cagcggccgc atcaccggga tcgacgcaag cagcgcccag
    19381 gcggaggagg gcgtactcgc cgtcctgacc caccagaacc tgccgaggat cgcggagcag
    19441 ccgccgctgg tcccctccct ggccggcacc gccgcccctg ggcagacctt cttcccgatg
    19501 caggacgaca tcgtccacta cgcgggccag cacatcgcga tcgtcgtcgc cgacacctgg
    19561 gagcgggcac agcacgcggc gagcctgctg cgcgtctcct acgaggagac gcccccggtc
    19621 accaccctcg agcagggccg cgaccaggca tacgaacccg agcgcatctt cggcggctgg
    19681 ctgccgggcc gggtggagcg cggaaacatc gatgcggggc tcgccgaggc ggacgcgcgg
    19741 gtggaggcca cgttcacgta cgccgcgaac aaccacaacc ccatcgagcc gtcgtgcacc
    19801 accgccgagt gggacggcga cgagctggtg ctgtacgact ccacccaggg cgtcaacgcg
    19861 acccagctca ccgtcgcgcg cctgctcggg accccactgt cgaagattcg cgtcatcggc
    19921 cactacgtcg ggggcagttt cggctcgaaa gccatgatcc acgaccatgc ggcactggcc
    19981 gcgatggctg cccgggaggt cggcaggcct gtcaaactcg cgctgagccg tgagcagatg
    20041 ttcacctcgg tcgggcaccg cgaggagcag gagcaggaga tcgtcctcgg tgcgacgcgc
    20101 gacggccggc tgaccgggat ccggcaccac aagctgtccc ccacctcgca cttcgacgac
    20161 tgggccgagc cctcgatcgg cgtcgcgtcg gagatctacg cgtgcccgaa ctaccagggc
    20221 gtgtaccggc tcttccgggc caacacgatg acaccgacct ttatgcgggc gcccggggag
    20281 gcgagcggca tgctcgcgct cgagtgcgcg atggacgagc tggcccagga actcggtgtg
    20341 gagccgatcg agctgcggct gcgcaactac acggacgcga gcccctcgtc gggccacccg
    20401 tggtccagca gcgggctgcg ggagtgttac cggcgtggtg ccgcgcgctt cggctgggag
    20461 ggccgcgatc cgcggccggg catgcgcagg gaggggaact ggctgatcgg gacgggcatg
    20521 gccagtgcgg gctacccggt cgctccgccc gccaatccgc agcgcgcccg cgcccgcctc
    20581 tacgccgacg gcaccgccct cgtccaggcc gccacccccg acttcggcac gggtgtggcc
    20641 acggtcatga cgcaggtcgc cgccgacggg ctcggcatgc cggtggaccg ctgccggttc
    20701 gagaacggcg acaccgacct gcccaacatc gcggccgcgg tgggctccgc gggcgccgga
    20761 atgatcagcg ccgcggtgca cagcgcggcg accgccctgc gcaaccagct gatcgccagg
    20821 gccgtcgcgg acgccaactc cccgctgcac ggcgcgaacc cggtcgacgt ggtcgtacgg
    20881 gacggggtca tgacggccgg gactgcctcc gattcctacg tcgacctgct gcaacggaac
    20941 gtccagccgg acgccgaggc gtccggtgcc tggagtccgc cggccggcga cgccccgtac
    21001 gcgatgatga cgttcggtgc ccagttcgcc gaggtggccg tggatcccga attcggtctg
    21061 gtccgggtgc ggcg
//
