LOCUS       NZ_BMMM01000009        22208 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces albiflavescens strain CGMCC 4.7111 sequence09, whole
            genome shotgun sequence.
ACCESSION   NZ_BMMM01000009
VERSION     NZ_BMMM01000009.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces albiflavescens
  ORGANISM  Streptomyces albiflavescens
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 424854)
  AUTHORS   Sun,Q. and Zhou,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 100X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014645835.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 03:24:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,828
            CDSs (total)                      :: 9,745
            Genes (coding)                    :: 9,386
            CDSs (with protein)               :: 9,386
            Genes (RNA)                       :: 83
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 359
            CDSs (without protein)            :: 359
            Pseudo Genes (ambiguous residues) :: 0 of 359
            Pseudo Genes (frameshifted)       :: 102 of 359
            Pseudo Genes (incomplete)         :: 321 of 359
            Pseudo Genes (internal stop)      :: 17 of 359
            Pseudo Genes (multiple problems)  :: 80 of 359
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:54:32
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 369452
            Orig. end                         :: 391660
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMMM01000009.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22208
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22208
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22208
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12208](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12208
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    38..52
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.96"
                     /tool="antismash"
     misc_feature    complement(302..316)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.98"
                     /tool="antismash"
     gene            complement(702..1133)
                     /locus_tag="IEY95_RS25410"
                     /old_locus_tag="GCM10011579_051470"
     CDS             complement(702..1133)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996943.1"
                     /locus_tag="IEY95_RS25410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_051470"
                     /product="DUF6114 domain-containing protein"
                     /protein_id="WP_189188419.1"
                     /transl_table=11
                     /translation="MSSARNPRSGFRQWRAHRPFWGGLLLTLAGAEILLTEKASLKVVM
                     HIGMQGLAGYLLPTLMLLCGLLILFNPTQRLFYSLLGILLSLGTWLTSNLGGFLIGLLL
                     GAIGSCLTFGWLPDQEPRRRLLRGRREQQRTATEAQGLS"
     gene            complement(1133..1816)
                     /locus_tag="IEY95_RS25415"
                     /old_locus_tag="GCM10011579_051480"
     CDS             complement(1133..1816)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996942.1"
                     /locus_tag="IEY95_RS25415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_051480"
                     /product="DUF6230 family protein"
                     /protein_id="WP_189188420.1"
                     /transl_table=11
                     /translation="MASSSDATASNGSTPETPENAESGSAADTSDRRGRVRLRRAAVMA
                     LPATAIAAGLMILTAQGALGVQFAISGMPFTVTATELNGTGFEQFGGLDNMAEGSPNAG
                     DTGGQVLVVTSAIKSATLTKLCQSVDLGGTNLLITAGSGADKVQASHLTTDSTELSGDA
                     SFDNIEIGNDAGTLDKAGVQGPKGVFSQQADTVRIANLRQTNYATTAAVFKLPGLKLRF
                     SDTGC"
     gene            2418..3083
                     /locus_tag="IEY95_RS25420"
                     /old_locus_tag="GCM10011579_051490"
     CDS             2418..3083
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431989.1"
                     /locus_tag="IEY95_RS25420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_051490"
                     /product="Tat pathway signal sequence domain protein"
                     /protein_id="WP_189188421.1"
                     /transl_table=11
                     /translation="MRTRSLLALVGVAAALSVSAAVPASAADTPVLTTGAAGGTPVATG
                     DVLSASLASGTAATLYSSSTGTSGVSCSSSTFTATVADNPAAPGAATESLTGHTFDSST
                     CTSNVTGVLGVTSITVDNLPYTTTVASDGTVTVTPAAGSTIQTTVKLRTLLGSITCVYQ
                     APSLSGTASNTDNSIAFTNQQFTKTSGSSLCFGNGYFTAKYAPVTDTSQSGSPAVFVN"
     gene            complement(3088..4005)
                     /locus_tag="IEY95_RS25425"
                     /old_locus_tag="GCM10011579_051500"
     CDS             complement(3088..4005)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014174386.1"
                     /locus_tag="IEY95_RS25425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_051500"
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="WP_189188422.1"
                     /transl_table=11
                     /translation="MTAYRTATAAAVAVAAPLLLATWAAGPAQAHGAPTDPVSRVAACS
                     PEGGTLIRTAACKAAIAANGAPFTAWDNLRVAGVNGRDRQVIPDGHLCSGGLPAYKGLD
                     LARADWPSTRLTSGGSFTLRYSSTIPHTGTFKLYLTKPGYDPTRPLKWSDLPTQPFATA
                     TDPALVNGAYRIKAKLPSDRTGRQMLYTIWQNSSTTDTYYSCSDVVLSGGRAASTAAAQ
                     NTRRTTAPARQTPTPARTTTSPTPTTEPPSLVTTSPAQETAPDHLAPAADSTSGGSAAL
                     PLVAGGTAALLLTAGVAVTIRRRR"
     misc_feature    complement(4262..4278)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.0"
                     /tool="antismash"
     gene            4439..6250
                     /locus_tag="IEY95_RS25430"
                     /old_locus_tag="GCM10011579_051510"
     CDS             4439..6250
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020122073.1"
                     /locus_tag="IEY95_RS25430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_051510"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_229703335.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 1.7e-52, bitscore:
                     173.0, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPSPSPSPSRGGRRKLLSVAAISAALLAGTTTTVAAQPSTGTVR
                     VTPAAQSAAAPAERLIVGYKSGAPEAKSNQAADADAQVKGEKAGEDLDFQRRLGTGAAL
                     VDLGTELKKADVADVIAQYRADPQVAYVVPDRLNKPQADPNDTEYAKQWDLFESTAGMR
                     VPGAWSTSTGSGVTVAVIDTGYVAHSDVAANIVGGYDFISDTAVSVDGDGRDSNPADPG
                     DWYATDECGAGTGSSSSSWHGTHVAGTIAAVTNNNKGVAGIAYHAKISPLRVLGKCGGY
                     DSDIIDAITWASGGSVSGVPANTNVAKVINMSLGGSGACTSATQSAINAAVNRGTTVVV
                     AAGNDNDNASKYSPASCSNVITVAATGRTGSRASYSNYGSIVDIAAPGGEMSTGTANGI
                     LSTLNSGTKTPSSESYAYYQGTSMATPHIVGLVALMKSANPSLTPAQIESAIKANARAL
                     PGTCSGGCGAGLADATKTVQAVASSGGSTGGTTFSNTTALSIPDAGSAVESSIAVSGRS
                     GNAPSTLQVGVDITHTYRGDLVIDLVAPDGSTYRLKSSSTSDSADNVSATYTVDASSET
                     ANGTWKLRVQDVAAQDTGTLNSWKLTF"
     gene            6340..7539
                     /locus_tag="IEY95_RS25435"
                     /old_locus_tag="GCM10011579_051520"
     CDS             6340..7539
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996935.1"
                     /locus_tag="IEY95_RS25435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_051520"
                     /product="damage-control phosphatase ARMT1 family protein"
                     /protein_id="WP_189188424.1"
                     /transl_table=11
                     /translation="MPEHAETPDSPHSAAPVDAPVILSNAVGSFPWSVFAERHPALIRK
                     VRDAFPYGPEQHRALDALLKSSTEGVIEPLGAQAADREQWDAWGQEHFGRSWFDVPFLW
                     AESYWYRQLLEAVEYFVPGPWKGIDPFRPFKLAELDTPEADEELAALDELAKRPVEDQE
                     QALLHGSLWGNRADLGFRLAAKEGEPTVDSPLVANDGESLRALFAGGTLCLVADNAGRE
                     LIPDLLLIDHLLLHHRVGRAALHIKPYPYYVSDATTADVLDALRRLAAAKGAAADSGHR
                     LWSALTDGRLVVRAHPFSCAPLPYADMPDDLRQEFAEADVTIMKGDLNYRRLIGDRLWP
                     ATTPFAVPTAYFPGPVAALRTLKSDVIVGLDARTESALVAAEDQRWRTSGTHALIQVRS
                     "
     gene            complement(7544..8812)
                     /locus_tag="IEY95_RS25440"
                     /old_locus_tag="GCM10011579_051530"
     CDS             complement(7544..8812)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983605.1"
                     /locus_tag="IEY95_RS25440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_051530"
                     /product="cytochrome P450"
                     /protein_id="WP_189188425.1"
                     /sec_met_domain="p450 (E-value: 6.6e-19, bitscore: 62.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVARETAPPVPDVFDPRRYADGVPHAAYRTLRDHHPVAWQEEPE
                     VLGWPSGPGFWAVTRHADVVRVLKDSATYSSYLGATQIRDPEPDDLPFIRRMMLNQDPP
                     EHGRLRRLVSRAFTPRRVDRFASVARARARALLGRAAEEARAGDGTCDLVAAVTDDYAL
                     LNLTDLLGVPEGDRELLLHWTQRVIGYQDPDEAGEPVLDARGRPVNPRSPAMLRDMFGY
                     AHQLAVHKKSHPGDDVMTTLANDPELAPAELEMFFFLLTVAGNDTVRSAAPGGLLALAE
                     HPDAYDGLRAGRIALDTAVEELLRWHPPVLTFRRTAAVDTELAGQRIRAGDKVVVFHAS
                     ANHDKRVFTDPHRLDLARTPNPHVSFGDGPHICLGAHFARLQLRVLHEETLRVLPSLRT
                     AGPPRRLVSNFINGLKSLPVEVT"
     gene            complement(8809..9723)
                     /locus_tag="IEY95_RS25445"
                     /old_locus_tag="GCM10011579_051540"
     CDS             complement(8809..9723)
                     /NRPS_PKS="Domain: Abhydrolase_1 (20-142). E-value:
                     1.4e-23. Score: 75.7. Matches aSDomain:
                     nrpspksdomains_IEY95_RS25445_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607007.1"
                     /locus_tag="IEY95_RS25445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_051540"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_189188426.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.5e-17, bitscore:
                     58.7, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 1.1e-19, bitscore: 65.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSFVLPHEVHGDGAHKVFAVHGWFADRSAYAAVLPDLDRAAFQY
                     ALVDLRGYGEAKDAVGAYTTAEAAADLVELADRLGWERFSVIGHSMGGAVAQRLPALAP
                     DRLRRLVGVSPVPASGLPMPADQWELFADAAHKPENRRAIIDFTTGGRRPAIWLDRMVA
                     RSLAVSEAKAFRAWLDSWAGEDFHTEVEGATVPALAVTGALDPALSAALMRETWLSWYP
                     CGEARELLGAGHYAMDETPLELIRVVEDFLRADDTGAPTTRRDDDTSAPATGPSDGSGA
                     LPTGPSDGSGAATTGRADEGDPA"
     aSDomain        complement(9298..9663)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEY95_RS25445_Abhydrolase_1.1"
                     /evalue="1.40E-23"
                     /label="IEY95_RS25445_Abhydrolase_1.1"
                     /locus_tag="IEY95_RS25445"
                     /protein_end="142"
                     /protein_start="20"
                     /score="75.7"
                     /tool="antismash"
                     /translation="VHGWFADRSAYAAVLPDLDRAAFQYALVDLRGYGEAKDAVGAYTT
                     AEAAADLVELADRLGWERFSVIGHSMGGAVAQRLPALAPDRLRRLVGVSPVPASGLPMP
                     ADQWELFADAAHKPENRR"
     CDS_motif       complement(9433..9468)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEY95_RS25445_0001"
                     /evalue="4.80E-04"
                     /label="NRPS-te1"
                     /locus_tag="IEY95_RS25445"
                     /protein_end="97"
                     /protein_start="85"
                     /score="12.7"
                     /tool="antismash"
                     /translation="VIGHSMGGAVAQ"
     gene            10001..12208
                     /gene="cyc2"
                     /locus_tag="IEY95_RS25450"
                     /old_locus_tag="GCM10011579_051550"
     CDS             10001..12208
                     /EC_number="4.1.99.16"
                     /EC_number="4.2.3.22"
                     /EC_number="4.2.3.75"
                     /codon_start=1
                     /gene="cyc2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019883993.1"
                     /locus_tag="IEY95_RS25450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_051550"
                     /product="germacradienol/geosmin synthase Cyc2"
                     /protein_id="WP_189188427.1"
                     /sec_met_domain="T1TS (E-value: 1e-81, bitscore: 270.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQPFELPHFYMPYPARLNPHLDEARAHSVEWARGMGMLEGSGIW
                     EQSDLDAHDYGLLCAYTHPDCDGPELSLITDWYVWVFFFDDHFLETFKRSQDRDGGKAY
                     LDRLPLFMPLDVSASVPEPENPVEAGLADLWARTVPSMSVDWRKRFAVSTEHLLNESMW
                     ELSNINEGRIANPVEYIEMRRKVGGAPWSAGLVEYATAEVPASVAGSRPLRVLMETFSD
                     GVHLRNDLFSYQREVEDEGELSNGVLVLETFFGCTTQEAAETVNDILTSRLHQFEHTAL
                     TEVPALAEEKGLAPDEIAAVAAYTKGLQDWQSGGHEWHLRSSRYMNEGALEGKRPFDAG
                     GFGTSAVDVGALLSAAGAERLRSYTHVPFQKVGPSRLPDFHMPFEVTLSPHLPGARARL
                     TGWMHAMGMLQEGVWDEDKLAAYDLPLCAAGIHPDATAEALDVSSRWLAWGTYGDDYYP
                     LVFGNRRDLAAARLTTARLSACMPIDGEEAPVPVNGMERGLIDLWQRTAAEMTPDERRR
                     FRSAVDVMTESWLWELSNQIQHRIPDPVDYLEMRRATFGSELTMSLCRLSHGRKVPPEV
                     YRSGPVRSLENAAMDYGMLMNDVFSYQKEIEYEGEVHNGILVVQNFFGCDYPTALGVIH
                     DLMTQRMRQFEHVAAHELPVLYEDFKLSEEVREIMQGYVVELQNWTAGILKWHQDCHRY
                     GAADLARRAHGFVPDQVPALPFTWPAAPVTAALRPGSPAAV"
     gene            complement(12286..13023)
                     /locus_tag="IEY95_RS25455"
                     /old_locus_tag="GCM10011579_051560"
     CDS             complement(12286..13023)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037066.1"
                     /locus_tag="IEY95_RS25455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_051560"
                     /product="hypothetical protein"
                     /protein_id="WP_229703336.1"
                     /transl_table=11
                     /translation="MTTNTAQTARIALVGDRSPNVVSHTRVPLLLDTLADRDRIVLDAY
                     WVPSEDAKDEEAVRGFDAVWVLPGSPYRSEAGVLTAIRTAREDGTPFLGTCGGFQHALL
                     EYARNVCDLAQVAHAENDPDADDFLIEPLACSLVGHEAAVTVEPGSLAQSVIGSERTVE
                     RYFCAYGPSRHLDALRAHGLRFSGHDEDGHVRIAELPGHPFYLATLFQPELSGDGSRPH
                     PIVRALARAAVAHAAVASEGQPV"
     misc_feature    complement(13072..13088)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.06"
                     /tool="antismash"
     gene            13119..13985
                     /locus_tag="IEY95_RS25460"
                     /old_locus_tag="GCM10011579_051570"
     CDS             13119..13985
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019071450.1"
                     /locus_tag="IEY95_RS25460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_051570"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_189188491.1"
                     /transl_table=11
                     /translation="MDPHLLRTYVTVARLASFSEAARELGYTQSAVSQHIAALEQDLGT
                     PLLTRRPVAPTAAGERLLEHAGPLLLRLDAARADVARMVAAPEHGLTLAAAPTALGPRA
                     LAALPAAGVTLRVLARDDIPEAVATGTADLGLVDGLAAPSDPLRLPDVAPLTTHGVGEE
                     PVCVLLPASHPLARRTGLRLGDLVDARWLDAPGAGLPLDHLRAANGSGGFRPALRYEGT
                     DIRALTTLAAAGHGLTLLPCTAATGLPGAVAVPLVAPRLVHRVELVHGGSLRGAAATMA
                     DKLLEHA"
     gene            14078..14725
                     /locus_tag="IEY95_RS25465"
                     /old_locus_tag="GCM10011579_051580"
     CDS             14078..14725
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006381304.1"
                     /locus_tag="IEY95_RS25465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_051580"
                     /product="PDZ domain-containing protein"
                     /protein_id="WP_189188429.1"
                     /transl_table=11
                     /translation="MEQTALRPKPMPGQEPGGGRPSGGPRRPHAARRRGRRLMSLLFGL
                     FVGMVLVLSGVGLGTVSATVIGMSKLADLQKQAGAQGAAGQPGRISGAPQAGGSKSASG
                     AGSSSPSKEPEKESEKESEKESGKATLGIEVVDASKDGGALLVGVHIPGPGYTAGLVRG
                     DVLLAFGESRITSAADLARAVAAAHPGSTVTLTVRHANGSRQRLSTVPGVVT"
     gene            14958..15578
                     /locus_tag="IEY95_RS25470"
                     /old_locus_tag="GCM10011579_051590"
     CDS             14958..15578
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1116:
                     Homoserine/threonine efflux protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385486.1"
                     /locus_tag="IEY95_RS25470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_051590"
                     /product="LysE family translocator"
                     /protein_id="WP_189188430.1"
                     /transl_table=11
                     /translation="MLSTLLAFLGACTLIAASPGPSTVLIIKRSLRSRRSGFLTVLGNE
                     TGVFVWGVVAAFGLTALLAASEMAYDIMRIVGAAVLIAFGVQTLWQARRSKGAVDGGWE
                     DAEKSGWASYRGGLLLNLANPKAAIFAMSFLPQFVPEGAPHLPTMVGLAALWAVYEVGY
                     YGLYVWFVGRMKAVLSRTGVRRRLEQVSGGVLLLLGARLALES"
     gene            15674..16795
                     /locus_tag="IEY95_RS25475"
                     /old_locus_tag="GCM10011579_051600"
     CDS             15674..16795
                     /EC_number="3.4.11.9"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172: methionine aminopeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996926.1"
                     /locus_tag="IEY95_RS25475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_051600"
                     /product="aminopeptidase P family protein"
                     /protein_id="WP_189188431.1"
                     /transl_table=11
                     /translation="MTGTPAPFTADDYEARMRRAAEAAADAGLAGVLVAPGPDLVWLTG
                     YRPVETERLTLLVLRAGEDPVLVVPTLEAPDAAKATGAPALTLRDWTDGKDPYEATASL
                     LAPEGRFGVSDNAWALHLLGLQKRLPDSRHVALTEALPMLRAVKDAAELERLAAAGAAA
                     DATFEEIRRVPFVGRREADVAADIADLLRRFGHSQVDFTIVASGPNGANPHHEAEDRII
                     QRGDMVVLDFGGLKDGYGSDTSRTVHVGEPDDEERKVYDIVRAAQEAGFRAVRPGVACQ
                     DVDRAAREVITEAGYGEYFIHRTGHGIGVTTHEPPYMIEGEQQPLVPGMCFSVEPGIYL
                     PGRFGVRIEDIVTVTEDGGRRLNTTSRELVIVD"
     gene            16861..17805
                     /locus_tag="IEY95_RS25480"
                     /old_locus_tag="GCM10011579_051610"
     CDS             16861..17805
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019062768.1"
                     /locus_tag="IEY95_RS25480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_051610"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_189188432.1"
                     /sec_met_domain="APH (E-value: 8.4e-24, bitscore: 79.3,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQAPTPSADTVRRLVRSLVADGLAAGAGPDVRPVAEGGEHSTWW
                     VGTRHVLRLAQDRDASVLQRRELRLRDLVRPHIGVPVPVSVAHGEWASGLSCTLDTRLP
                     GVSGEKQAVSAVGEADLAGLLTGLREVPVRQAEALGVPRAAPRSLEELRTAAAHAAEEL
                     AAAEEFDPARLAQLTAPAALQLAAQPAAAILVHHDLKGEHLMVSADGRVRGVLDWADAV
                     IGDPAEDIAGLAIAVGAPAAVRAATLAGYGPRPCLRGLWLSRCDTVIRLADRLHGRRDD
                     SPVPLLETQLRRAWEAILLERVTDLRDGLDETP"
     gene            complement(17927..19672)
                     /gene="treZ"
                     /locus_tag="IEY95_RS25485"
                     /old_locus_tag="GCM10011579_051620"
     CDS             complement(17927..19672)
                     /EC_number="3.2.1.141"
                     /GO_function="GO:0033942 -
                     4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0005992 - trehalose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="treZ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1297: Pullulanase, type I"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020133692.1"
                     /locus_tag="IEY95_RS25485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_051620"
                     /product="malto-oligosyltrehalose trehalohydrolase"
                     /protein_id="WP_189188433.1"
                     /sec_met_domain="Alpha-amylase (E-value: 1.3e-11, bitscore:
                     39.1, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFDVWAPQADRVTLHCAGATRALERDRERTGWWTGDADAQDGTR
                     YGFAVDDGPVLPDPRSRRQPDGPDGLSAVVDQGRYDWRTEWAGRPLPGAVLYELHVGTY
                     TPEGTLDAAAERLGHLAELGVTHVELMPLCPFPGRHGWGYEGVSPWAVHEPYGGPEALK
                     RFVDRAHEVGLGVVLDVVHNHLGPSGNHLPAFGPYFTDTHQTPWGSAVNLDAPGSDEVR
                     AYFVGSALAWLRDYRLDGLRLDAVHALRDTRAVHFLEQLSTAVDALADDLGRPLFLIAE
                     SDVNDPRTVTPREEGGLGMHAQWNDDFHHALHTALTGEAQGYYADFARAPFTALAKTIT
                     SGYFHDGTYSSFRGRSHGRPLDRTRVSAHRLLGYAQTHDQIGNRAQGDRLSASLSPGLL
                     ACAAALTLTAPFTPMLFMGEEWAAGTPWQFFTDHTDPELAEAVRRGRRREFAAHGWAEE
                     DVPDPQDPATRDRSCLDWSEPEKAVHARVLAWYRDLIALRRRQADLSDPDLAAVRVAHD
                     AQARWLALRRGDVRVAVNLAKETAAIPLGIRHARVLAAWEPVEAPDGDGVLRVPGESCV
                     VLTQA"
     misc_feature    19726..19741
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.21"
                     /tool="antismash"
     misc_feature    complement(19729..19744)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.8"
                     /tool="antismash"
     misc_feature    complement(19788..19802)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.31"
                     /tool="antismash"
     gene            19866..20417
                     /locus_tag="IEY95_RS25490"
                     /old_locus_tag="GCM10011579_051630"
     CDS             19866..20417
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005481978.1"
                     /locus_tag="IEY95_RS25490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_051630"
                     /product="DUF1707 and FHA domain-containing protein"
                     /protein_id="WP_189188434.1"
                     /transl_table=11
                     /translation="MTSSFEFHTYPARLSDAERDRALKALRDGVALGRLSHDTFIRRME
                     LALAARRSDELAVLTADLPTEGRWSKLVFGTVEAVSGFTVRVRRAWQAERLPKLLLPHP
                     GSLYPLRIGRDPASGLRLNHETVSRVHAELSRQGGVWVLRDLGSTNGTTVNGRRVIGAA
                     VVRDGDQIGFGRMMFRLASE"
     gene            20813..22138
                     /locus_tag="IEY95_RS25495"
                     /old_locus_tag="GCM10011579_051650"
     CDS             20813..22138
                     /GO_function="GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019062765.1"
                     /locus_tag="IEY95_RS25495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10011579_051650"
                     /product="M14 family zinc carboxypeptidase"
                     /protein_id="WP_229703338.1"
                     /transl_table=11
                     /translation="MDELGARAAALVARRPRDARLRRVGTSRAGTPLWLLSVGHGTRQV
                     LVVAGPHANEPVGGATALRLAERALADPRLTEGADATWNLLLCLDPDGSRRNEAWLSGP
                     YTLGQYFRHFFRPGFLEQPEWLPEGADGATLPETRALLDLQDELRPFLQCSLHGVDVGG
                     AFVELTRELPGLAQRVAHTAARLGIPRELGPYDTLYWPALGPAVYRIPPPRRGGLAAAI
                     TEAAVESTWFHPHSYGTVTAVVEAPMWGVAAVEDATRPADADAMLRTISRTLRRDTGLL
                     EGILARVRPSLGASPDVACLLAPVDDYLLVGPGLADSWDPDVYDAGARPLPPLDTARLT
                     ALRLAGRRVALRTAGLLHQLVSASGHDPCGVQPELDRLLDEWCADYREGCGARWIPVAR
                     QVEYQARVVLASFELAGRHAPVRSRSGESGWGSEATVPMHLE"
     misc_feature    21737..21739
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 taggcggcgg tcatctcacc cgggtcggcg gaggtgtcga agatgcggtc caccaactgc
       61 cgcagctcgg gcccccgctc ctcgggcagg ccgaacagct cactgatcac ctggatcggc
      121 agcgggtagc agagttcctc gcgcaggtcg acgacctggg actcgcgccc ggcctccgcg
      181 atccggtcga ggagccgctc ggtgatctcc tcgatacggg gctggagcgc agccgtccgg
      241 cgtgcggtga acgccttgga gaccaggatg cgcagccgtt tgtggtcgcc gccgtacgcg
      301 gtgaacatgt tctgcacggc gacccaggtg aacagcggcc agtccggtgt gatctccccg
      361 ttcgcgagcg ggggccagtg ctgccgggcg tccttggaaa cccggggatc ggtcagcagc
      421 cgtttgagca gctcaggact gctgaccgcc caggcctcca cgccaccggg gagcgccacg
      481 ggggtcgccg gccccctggc gcggatgcgg gcggcttctg cgtgaatgtc gcggcctgtc
      541 gcgtctatca ctaaggggct tgggtttccc atcgggagcc tccctggcac tcgaacgtca
      601 acacggcagg tcacgctacg cgggagtacg gttccccagc gagaccgcct gacgccacat
      661 tcgtacgcgg gcaacttccc tgcgcataca cgcaagtggt cctacgacag gccctgggcc
      721 tcggtcgccg tccgctgctg ttcacggcgg ccccgcagca gtcgccggcg tggctcctgg
      781 tccgggagcc agccgaaggt gaggcagctg ccgatggctc cgaggagcag gccgatgagg
      841 aagccgccca ggttggaggt gagccaggtg ccgagggaga ggaggatgcc gagcagggag
      901 tagaagaggc gctgggtggg gttgaagagg atcagcaggc cgcagagcag catcagggtg
      961 gggagaaggt atccggccag gccctgcatg ccgatgtgca tgacgacctt cagggacgcc
     1021 ttctcggtca gcaggatctc cgccccggcc agggtgagca gcaacccgcc ccagaagggg
     1081 cggtgcgcgc gccactgccg gaaaccggac ctcgggttac gggcggagga catcagcaac
     1141 ccgtgtcgct gaagcggagt ttgagaccgg gaagcttgaa caccgcagcg gtggtcgcgt
     1201 agttggtctg ccgcaggttc gcgatgcgca cggtgtcggc ctgctggctg aacacgccct
     1261 tggggccctg gactccggcc ttgtcgagcg tgccggcgtc gttgccgatc tcgatgttgt
     1321 cgaaggacgc gtctcccgac agctcggtcg agtcggtggt cagatggctt gcctgcacct
     1381 tgtccgctcc gctgcccgcg gtgatgagca ggttcgtacc tcccaggtcg acgctctggc
     1441 acagcttggt cagggtcgcg ctcttgatcg cggaggtgac gaccaggacc tggccgccgg
     1501 tgtcgccggc gttcgggctg ccctccgcca tgttgtcgag gccgccgaac tgctcgaagc
     1561 ccgtgccgtt gagctccgtc gccgtgaccg tgaacggcat gccggagatg gcgaactgga
     1621 cgcccagggc gccctgggcg gtgaggatca tcagtcccgc ggcgatcgcg gtggcgggca
     1681 gcgccatcac ggcggcgcgg cgcaggcgga cccgcccgcg tctgtccgac gtgtcggcgg
     1741 cggaaccgct ttccgcgttc tccggggtct cgggggtgga accgttggac gccgtggcgt
     1801 ccgaggacga ggccatgtct gctccctggg catggtcgat gcgggtaggg gtccagtggc
     1861 acgttgtcct ggcgcggaca gcggctgccg cgcacgcctc ctcacctctc ccggaggagg
     1921 caagggcttt ctcgttacgc ggcagtagcc gccgaggaag ttacccgggg ttacattcgc
     1981 ggtcaagtga cgtgtgagaa aagggtgttg gttgtgccat gcctgtgaat acgacgcgac
     2041 ggcgtggccg ctctgacctt caacttcctt ggcccgcctt gacgttgacc cttcaccagg
     2101 tctacaactc tcccttgttt cccacggatc cgtggcgccg gatccgttgc ggtgcgcgca
     2161 cgtcacctcc cggaccccga tctgtacggg gcagtcgtga cacgtccgaa cgcgcagtgc
     2221 gcccactcgc ccacccccca cccccgtggc accggcgcgg tcgccttccc cctgggccgt
     2281 gtccggtcgc ccggctgtcg ccgccggtcc gtggcgtacg gagaagacgc cacggaccgg
     2341 cggcggttca cccccgcacg ccccgcgccc cgcgcggcca ggcaccccac acccccttcg
     2401 gagaagaggc accccccatg cgtactcgat ccctccttgc cctcgtcggc gtcgccgcgg
     2461 ccctctcggt gtcggcggcc gtccccgcct ccgctgccga caccccggtg ctcaccaccg
     2521 gggccgcagg cggaaccccc gtcgccaccg gtgacgtcct cagcgcctcg ctggcgagcg
     2581 gcaccgcggc cacgctctac tccagcagca ccggcacgag cggcgtctcc tgctcctcgt
     2641 cgaccttcac cgccaccgtc gccgacaatc cggcggcccc cggtgcggcc accgagtcgc
     2701 tcaccgggca cacgttcgac agcagcacgt gcaccagcaa cgtgaccggc gtgctcggcg
     2761 tcaccagcat cacggtcgac aacctgccgt acaccaccac cgtggcctcc gacggcaccg
     2821 tcaccgtcac cccggcggcc ggctccacca ttcagaccac ggtcaagctg cgcaccctgc
     2881 tgggcagcat cacctgtgtc taccaggcgc ccagcctgtc cgggacggcg agcaacacgg
     2941 acaacagcat cgccttcacc aaccagcagt tcacgaagac ctccggctcg tccctgtgct
     3001 tcggcaacgg ctacttcacc gccaagtacg cgcccgtcac ggacaccagc cagtcgggga
     3061 gcccggcggt cttcgtcaac tgaccgctca gcggcggcgc cggatggtga cggcgacccc
     3121 cgcggtgagg aggagcgccg cggtcccccc ggccacgagg gggagcgcgg cgctgccgcc
     3181 cgaagtgctg tcggcggcgg gcgccaggtg atccggcgcc gtctcctgag ccggtgacgt
     3241 ggtcacgagt gacggaggct cggtcgtcgg cgtcggcgac gtggtcgtcc gggcgggcgt
     3301 gggcgtctgc cgtgccggtg ccgttgtcct ccgggtgttc tgcgcggcgg ccgtcgaggc
     3361 cgcacgccca ccggacagaa cgacgtccga gcacgagtag tacgtatccg tcgtgctcga
     3421 gttctgccag atcgtgtaca gcatctggcg gccggtccga tcggacggca gcttggcctt
     3481 gatgcggtag gcgccgttca ccagagccgg atcggtggcg gtggcgaacg gctgcgtcgg
     3541 caggtcggac cacttcaagg gccgggtcgg gtcgtaaccc ggcttggtca gatacagctt
     3601 gaacgtcccc gtgtgcggga tcgtcgagct gtacctgagg gtgaagctcc cgccggaagt
     3661 cagccgggtc gagggccagt ccgcgcgggc gaggtcgagg cccttgtagg cgggcaggcc
     3721 cccgctgcac aggtgcccgt cggggatcac ctggcggtcc ctgccgttga cgccggccac
     3781 cctgaggttg tcccaggcgg tgaagggcgc gccgttcgcg gcgatcgccg ccttgcaggc
     3841 cgcggtccgg atcagggtgc cgccctcggg cgagcaggcc gcgacccggc tgaccggatc
     3901 cgtcggcgca ccgtgcgcct gggcgggccc cgcggcccac gtcgcgagga gcagcggagc
     3961 cgccacggcg acagcggccg cggtggcggt gcggtaggcg gtcatccggt gggtctcctc
     4021 ggtatgtcgg cgaagcggag cgggattccg gcggcgtggc cgagagccgt cgcggcggat
     4081 gccaccgcgc gcggcctgga cgcactcctc gctcggggca ccgtgaagta cggggccgcg
     4141 gagccgagcg ttcagcgccg tgatacgcgc gaaacggcat cttcttggcc aactgacccc
     4201 gagagagggt cggttaccgg ccagatcgag ggtttcccct gtatccctct tacctgccct
     4261 ttgcctatcg ttcgagcaca ggcgacccac aggaaacccc tccccgggtc gtacgcgcat
     4321 ggccggccgc cgcgccgctt tctggttttg caccccccgc cgcttcgacg acgaagcgaa
     4381 tcgaccgctg ctccgcatcg caccgcgctg cccggagccg gctccgaaag gcaagccctt
     4441 gcgtccctcc ccctcgccct ccccgtcccg cggcggcaga cggaagctgc tgtccgtcgc
     4501 cgcgatatcc gccgcgctgc tggccggaac gaccaccacg gtggccgccc agccgtccac
     4561 cgggaccgtg cgggtcaccc ccgccgcgca gtcggccgcc gccccggccg agcgcctgat
     4621 cgtcggctac aagtccggcg cccccgaggc caagtccaac caggccgccg acgccgacgc
     4681 ccaggtcaag ggcgagaagg ccggcgagga cctcgacttc cagcgccgcc tcggcaccgg
     4741 cgcggccctg gtcgacctcg gcaccgagct caagaaggcg gacgtcgccg acgtcatcgc
     4801 gcagtaccgg gccgacccgc aggtcgccta cgtcgtaccg gaccgcctca acaagccgca
     4861 ggcggacccg aacgacaccg agtacgccaa gcagtgggac ctgttcgagt ccacggcggg
     4921 catgcgcgtt ccgggcgcct ggtccacgtc caccggcagc ggggtgaccg tcgccgtcat
     4981 cgacaccggt tacgtggccc actccgacgt cgccgcgaac atcgtcggtg gctacgactt
     5041 catctccgac acggcggtct cggtcgacgg cgacgggcgc gacagcaacc cggccgaccc
     5101 gggcgactgg tacgcgaccg acgagtgcgg cgcgggcacc ggctccagca gctcgtcctg
     5161 gcacggcacc cacgtggcgg gcaccatcgc cgccgtcacg aacaacaaca agggtgtcgc
     5221 gggcatcgcg taccacgcga agatctcccc gctgcgtgtc ctcggcaagt gcggcggcta
     5281 cgactcggac atcatcgacg ccatcacctg ggcctccggc ggcagcgtct ccggcgtccc
     5341 ggccaacacc aacgtcgcca aggtcatcaa catgagcctc ggcggctcgg gcgcctgcac
     5401 ctccgccacc cagagcgcca tcaacgcggc cgtgaaccgc ggtacgacgg tcgtcgtggc
     5461 cgcgggcaac gacaacgaca acgcctccaa gtactccccg gcgagctgca gcaacgtcat
     5521 caccgtcgcc gccaccggcc gtaccggctc ccgcgcctcg tactccaact acggctcgat
     5581 cgtcgacatc gcggcccccg gcggcgagat gagcacgggc accgccaacg gcatcctgtc
     5641 cacgctcaac tccggtacga aaacgccgtc ttcggagtcg tacgcgtact accagggcac
     5701 cagcatggcc accccgcaca tcgtcggcct tgtggcgctg atgaagtcgg cgaacccgtc
     5761 gctgactccg gctcagatcg agtccgccat caaggccaac gcccgtgcgc tgcccgggac
     5821 gtgctcgggc ggctgcggtg cgggactcgc ggacgcgacc aagaccgtcc aggcggtggc
     5881 gtccagcggc ggttcgaccg gtggcaccac cttctccaac accaccgccc tgtcgatccc
     5941 ggacgccggc tccgccgtcg agtcgtcgat cgccgtcagc ggccgcagcg gcaacgcgcc
     6001 ctccaccctc caggtcggcg tcgacatcac ccacacctac cgcggtgacc tcgtcatcga
     6061 cctggtcgcg cccgacggtt cgacctaccg cctgaagtcc tccagcacct cggactccgc
     6121 ggacaacgtc agcgccacct acaccgtcga cgcctccagc gagacggcga acggcacctg
     6181 gaagctgcgc gtccaggacg ttgccgcgca ggacaccggc acgctcaaca gctggaagct
     6241 gaccttctag cggaccggtt gagctctacg gggggagggg tcgtccgacg cgcacgcgcg
     6301 tcggccggcc ccttctgctc ggccggtacg gtgagcggca tgcccgagca cgccgagacc
     6361 cccgattccc cccattccgc agctcccgtc gacgcgcccg tgatcctcag caacgcggtg
     6421 gggtcgtttc cctggagcgt gttcgccgag cggcacccgg cgctcatccg gaaggtgcgg
     6481 gacgccttcc cttacggtcc cgagcagcac cgcgcgctcg acgccctgct caagagcagc
     6541 accgagggcg tcatcgaacc gctcggcgcg caggcggcgg accgggagca gtgggatgcg
     6601 tgggggcagg agcacttcgg gcgatcctgg ttcgacgtgc ccttcctctg ggccgagagc
     6661 tactggtacc gccaactcct cgaagccgtc gagtacttcg tcccgggccc ctggaagggc
     6721 atcgacccct tccggccctt caagctcgcc gaactcgata ccccggaggc cgacgaggaa
     6781 ctcgccgcgc tggacgaact cgcgaagcgg ccggtcgagg accaggagca ggcgctgctg
     6841 cacggctcgc tgtggggcaa ccgcgcggac ctcggcttcc gcctggccgc caaggagggc
     6901 gagccgacgg tcgattcccc actggtcgcc aatgacggcg agtcgctgcg ggcgttgttc
     6961 gccggcggca cgctctgcct ggtcgcggac aacgcgggcc gggaactcat ccccgacctg
     7021 ctcctcatcg accatctcct cctccaccac cgtgtcgggc gggccgccct gcacatcaag
     7081 ccgtacccgt actacgtctc cgacgccacg accgccgacg tgctcgacgc gctgcgccgc
     7141 ctcgccgccg ccaagggtgc cgccgccgac tccggccacc gcctctggtc ggccctgacc
     7201 gacggccgcc tcgtggtgcg ggcccacccc ttctcctgcg ccccgctgcc gtacgccgac
     7261 atgcccgacg acctccgtca ggagttcgcc gaggccgatg tgacgatcat gaagggcgat
     7321 ctgaactacc gccgcctcat cggcgaccgg ctgtggcccg ccaccacacc cttcgccgtt
     7381 cccaccgcgt acttccccgg cccggtggcc gccctgcgca ccctcaagtc cgatgtgatc
     7441 gtcggtctcg acgctcgcac cgagtccgcg ctcgtcgccg ccgaggatca gcgctggcgc
     7501 acgagcggca cgcatgcgct gatccaggtg aggtcctgat ccgtcaagtc acctccacag
     7561 ggagcgactt gagaccgttg atgaagttcg agacaaggcg tcggggaggt ccggcggttc
     7621 gtagcgaggg caggacgcgc agcgtctcct cgtggagcac gcgcagctgc agccgggcga
     7681 agtgggcacc gaggcagatg tgcgggccgt cgccgaagga gacgtggggg ttcggggtcc
     7741 gggcgagatc gagccggtgc gggtcggtga acacacgctt gtcatggttg gccgaggcgt
     7801 ggaagacgac caccttgtcg cccgctcgga tgcgctgccc ggccagttcg gtgtcgacgg
     7861 ccgcggtacg gcggaaggtg agcacgggag gatgccaacg cagcaactcc tcgacggcgg
     7921 tgtcgagagc gatgcgaccc gcgcgcagtc cgtcgtacgc gtccgggtgc tccgccagcg
     7981 ccagcagacc cccgggagcg gcactgcgta cggtgtcgtt gcccgccacg gtgagcagga
     8041 agaagaacat ctccagctcg gcgggggcga gttcggggtc gttcgcgagg gtggtcatca
     8101 catcgtcgcc gggatggctc ttcttgtgga cggccagctg gtgcgcgtac ccgaacatgt
     8161 cccgcagcat cgcgggggag cgcggattga cgggccggcc ccgagcgtcg agcacgggct
     8221 cgcccgcctc atcggggtcc tggtagccga tgacccgctg cgtccagtgc agcagcagct
     8281 cccggtcgcc ctccggcaca ccgagcaggt ccgtgaggtt gagcagggcg tagtcgtcgg
     8341 tgacggcggc gacgaggtcg caggtcccgt ctcccgcgcg agcctcttcc gccgcccgcc
     8401 cgagcagcgc acgggctcgt gcgcgcgcca ccgacgcgaa gcggtcgaca cggcgcgggg
     8461 tgaacgcacg gctgaccagg cgcctcaacc ggccgtgctc cggcgggtcc tgattgagca
     8521 tcatgcggcg gatgaacggc aggtcgtccg gttccggatc gcggatctgg gtcgctccga
     8581 ggtacgacga gtacgtcgcc gagtccttga ggacccggac gacgtccgcg tgccgggtca
     8641 ccgcccagaa ccccggtccc gacggccagc cgagcacctc gggctcctcc tgccaggcca
     8701 cggggtgatg gtcgcggagg gtgcggtacg cggcatgagg gaccccgtcg gcgtaccgcc
     8761 gtggatcgaa gacgtccggc acgggcggcg cggtctcacg cgcgacgctc acgcggggtc
     8821 gccttcgtcc gcacgcccgg tcgtggcggc gccggagccg tccgaaggcc cggtggggag
     8881 ggcgccggag ccgtccgaag gcccggtcgc gggagcgctc gtgtcgtcgt cgcggcgagt
     8941 cgtgggcgcg cccgtgtcgt ccgcgcgcag gaagtcctcg accacgcgga tcagctccag
     9001 aggggtctcg tccatcgcgt agtggccggc tccgagcagc tcacgtgcct cgccgcaggg
     9061 gtaccaggac agccaggtct cccgcatcag ggccgccgag agcgcgggat ccagcgcgcc
     9121 cgtcacggcc agcgcgggca ccgtcgcccc ctcgacctcg gtgtggaagt cctccccggc
     9181 ccaggagtcc agccaggctc ggaacgcctt cgcctcgctg acggcgagcg agcgggccac
     9241 catccggtcc agccagatgg ccgggcggcg gccgcccgtc gtgaagtcga tgatggcgcg
     9301 ccggttctcc ggtttgtgcg cggcgtcggc gaagagttcc cactggtcag cgggcatcgg
     9361 cagccccgac gcgggcaccg gggagacgcc gaccaggcgg cgcagccggt ccggggcgag
     9421 ggccggcaga cgctgggcga cggcgccgcc catcgagtga ccgatgaccg agaaccgctc
     9481 ccagccgagc cggtccgcca actcgacgag atcggccgcg gcctcggcgg tcgtgtacgc
     9541 gccgaccgcg tccttcgcct ccccgtagcc ccgcagatcg acgagcgcgt actggaacgc
     9601 ggcgcggtcc agatccggca gcaccgccgc gtacgcggac cggtcggcga accagccgtg
     9661 cacggcgaac accttgtggg cgccgtcgcc gtgcacttca tgggggagca cgaaggaggt
     9721 catgcgacca cggtgacccg ggggatgcgg gtcggcaagg gcgcgtgagg ccacgaggac
     9781 tgggcagttc cccgcgcccc gtcaggggcg cggggaactg cgcgacaagc ccccacgcac
     9841 ccgcagtcga agggctggta cgggacgggt aggggcggag ggggcgaaaa cctccctgta
     9901 cacctggcct tcacgcatcg aaaacgggtg gattcacgcg atggtgtgat catgtcccgg
     9961 cagccggatg tcgccggggg gccatgggta gtgcccggcc atgacgcagc cgttcgaact
    10021 cccgcacttc tacatgccgt atcccgcgcg gctgaacccg catctcgacg aggcacgggc
    10081 tcattccgtc gagtgggccc gcggaatggg catgctggag ggctccggca tctgggaaca
    10141 gtccgacctc gacgcgcacg actacggcct gctgtgcgcg tacacgcacc ccgactgcga
    10201 cgggcccgaa ctctccctga tcaccgactg gtacgtgtgg gtgttcttct tcgacgacca
    10261 cttcctggag acgttcaaac gcagccagga ccgcgacggc ggcaaggcct acctggaccg
    10321 gctgcccctc ttcatgccgc tggacgtctc ggcctccgta ccggagccgg agaatccggt
    10381 cgaggcgggc ctcgccgacc tgtgggcgcg cacggtgccc tcgatgtcgg tggactggcg
    10441 caagcgcttc gccgtgtcca cggagcacct gctcaacgag tcgatgtggg agctctccaa
    10501 catcaacgaa gggcggatcg ccaatcccgt cgagtacatc gagatgcgcc gcaaggtggg
    10561 cggcgccccc tggtcggcgg ggctcgtcga gtacgcgacc gccgaagtgc ccgcctccgt
    10621 cgccggatcc cggcccctgc gcgtgctgat ggagacgttc tccgacggtg tgcatctgcg
    10681 caacgacctc ttctcgtacc agcgggaggt cgaggacgag ggcgagctca gcaacggcgt
    10741 cctcgtcctg gagaccttct tcggctgcac cacccaggag gccgccgaga ccgtcaatga
    10801 catcctcacc tcacggctcc accagttcga gcacaccgcc ctcaccgaag tgcccgcgct
    10861 ggccgaggag aaggggctcg ccccggacga gatcgcggcc gtcgcggcgt acacgaaggg
    10921 cctgcaggac tggcagtcgg gcggccacga gtggcatctg cggtcgagcc gttacatgaa
    10981 cgagggggcg ctggaaggga agcggccgtt cgacgccggc ggcttcggca cgtctgccgt
    11041 ggacgtcggg gccctgctct cggcagccgg cgccgaacgg ctgcgctcgt acacccatgt
    11101 ccccttccag aaggtcggac cgtcccggct tcccgacttc cacatgccgt tcgaggtgac
    11161 gctcagcccg catctgccgg gcgcacgggc ccgcctcacc ggctggatgc acgccatggg
    11221 catgctccag gagggcgtct gggacgagga caaactcgcc gcctacgacc tgccgttgtg
    11281 cgcggccggt atccacccgg acgcgacggc ggaggcgctc gacgtcagct cccggtggct
    11341 tgcgtggggc acctacggcg acgactacta cccgctcgtc ttcggcaacc gccgcgacct
    11401 ggccgcggcc agattgacca ccgcacgtct gtcggcctgc atgcccatcg acggcgagga
    11461 ggcccccgtc ccggtcaacg gcatggagcg cggcctcatc gacctctggc agcgcaccgc
    11521 cgcggagatg accccggacg agcggcgccg gttccggtcc gcggtggacg tgatgacgga
    11581 gagctggctg tgggagctgt ccaaccagat ccagcaccgc atccccgacc cggtcgacta
    11641 cctggagatg cgccgagcca ccttcggctc cgaactcacc atgagcctgt gccgcctgag
    11701 ccacggccgc aaggtcccac cggaggtcta ccgcagcggc cccgtccgct cgctggagaa
    11761 cgcggccatg gactacggga tgctcatgaa cgacgtcttc tcgtaccaga aggagatcga
    11821 gtacgagggc gaggtccaca acggcattct cgtcgtgcag aacttcttcg gctgcgacta
    11881 cccgaccgcg ctcggtgtca tccacgacct gatgacccag cgcatgcggc agttcgagca
    11941 tgtcgccgcc catgaactgc ccgtcctgta cgaggacttc aagctctcgg aggaagtgcg
    12001 cgagatcatg cagggctatg tcgtggagct gcagaactgg acggccggga tcctgaagtg
    12061 gcaccaggac tgccatcgct acggcgcggc ggacctggcc cggcgtgccc acggcttcgt
    12121 accggaccag gtgcccgcgc tgccgttcac ctggccggcg gctccggtaa cggctgctct
    12181 gcgaccgggc tctcctgccg ctgtctgaca ctgacccggg ccgcctcgga gagttccgcg
    12241 aggagcgtcg cggtaccacg ccgcggctgc cgcgtgcccc tgtggtcaaa cgggctgccc
    12301 ctcgctcgcg acggccgcgt gggccacggc ggctcgcgcc agcgcccgca cgatcgggtg
    12361 cgggcgcgag ccgtccccgg acagctccgg ctggaagaga gtggccaggt agaaggggtg
    12421 tccggggagt tcggcgatgc ggacgtgccc gtcctcgtcg tgtccgctga agcgcagccc
    12481 gtgcgcgcgc agggcatcga ggtggcggga gggtccgtac gcgcagaagt agcgctcgac
    12541 cgtccgctcg gaaccgatca ccgactgggc cagcgagccg ggctcgaccg tgacggcggc
    12601 ctcgtggccc acgagcgaac aggcgagggg ctcgatgagg aagtcgtcgg cgtcggggtc
    12661 gttctcggcg tgcgcgacct gggcgagatc gcacacattg cgggcgtact cgagcagggc
    12721 gtgctggaaa ccgccgcagg tgccgaggaa cggggtgccg tcctcgcggg cggtgcggat
    12781 ggccgtgagc actcccgcct cactgcggta ggggctgccg ggcagcaccc acacggcgtc
    12841 gaagccgcgt accgcctcct cgtcctttgc gtcctcggac gggacccagt aggcgtccag
    12901 gacgatccgg tcgcggtcgg cgagagtgtc gaggaggagc gggacgcggg tgtgcgagac
    12961 gacgttgggg gagcggtcgc cgaccagagc gatccgggcg gtctgtgcgg tgttcgtggt
    13021 catgccgttc atcctgggcg cgcctcgtgg ttcacgtcca acgatgattt ctgcaccctt
    13081 gataagcaat gctgatgacg tacgggatcc tgggacgcat ggacccgcat ctcctgcgta
    13141 cgtacgtcac cgtcgcccgg ctcgcgtcct tctcggaggc cgcgcgcgag ctcggctaca
    13201 cccagtccgc ggtgtcccag cacatcgccg cgctggagca ggacctcggc acgcccctgc
    13261 tcacccggcg tccggtcgcg cccaccgccg cgggtgagcg gctgctcgaa cacgccggac
    13321 cgctgctcct gcgcctggac gcggcccgcg ccgacgtagc ccggatggtg gccgcgcccg
    13381 agcacgggct gacgctcgcc gccgcgccga ccgccctcgg accgcgtgcc ctcgcggcgc
    13441 tccccgccgc cggcgtgacc ctgcgcgtgc tggcccgcga cgacatcccc gaggcggtcg
    13501 ccaccggcac cgcggacctc ggcctcgtcg acgggctggc cgcgcccagc gaccctcttc
    13561 ggctgcccga cgtggcgccg ctgaccacgc acggcgtggg cgaggagccg gtctgcgtac
    13621 tgctgccggc ctcccatccg ctcgcccggc gcacggggtt gcgcctcggt gacctcgtcg
    13681 acgcccgctg gctggacgcc cccggcgcgg gactgccgct ggaccacctc cgtgccgcga
    13741 acggcagcgg cggcttccgc cccgccctgc gctacgaggg caccgacatc cgtgccctca
    13801 ccactctggc cgccgcggga cacggcctga ccctgctgcc atgcacggcg gccaccggcc
    13861 tgcccggagc ggtggccgtc ccgctcgtgg cgccccgcct ggtgcaccgt gtggaactgg
    13921 tgcacggcgg atcgctgcgg ggagccgcgg cgaccatggc ggacaaactt ctcgaacacg
    13981 cttgacagtc tcactcgttc gtgaatcgtc gcgcgccggc gcgcagggta gagcaagagc
    14041 cggaggcggt ccgtagagca tctgccggag gcgatccatg gaacagaccg cgttgcgtcc
    14101 caagccgatg cccggtcagg agccgggcgg cggccgtccg tccggcggtc cccggcgtcc
    14161 gcacgccgcg cggcggcgcg gcaggcggtt gatgagtctg ctcttcggcc tgttcgtcgg
    14221 tatggtgctg gtcctgtcgg gcgtcggact cggcaccgtg agcgccaccg tgatcggcat
    14281 gagcaagctg gcggatcttc agaagcaggc cggggcgcag ggggctgcgg ggcaaccggg
    14341 gcggatctcc ggcgcgccgc aggccggcgg ctccaagtcg gcctccgggg cggggagttc
    14401 gtccccttcc aaggaacccg agaaggagtc cgagaaggag tccgagaagg agtccgggaa
    14461 ggccaccctc ggcatcgagg tcgtcgacgc ctccaaggac gggggcgccc tcctggtcgg
    14521 tgtccacatc ccgggtccgg gctacacggc gggcctggtg cgtggcgacg tactgctggc
    14581 cttcggcgag agccggatca cctcggccgc cgacctcgcg cgcgcggtcg cggccgcgca
    14641 cccggggtcc accgtcaccc tcaccgtgcg ccacgcgaac ggcagccggc agcgattgtc
    14701 cacggtgcca ggtgtggtga cctgacgtcg caggacacgt cggaacgtca tccccgacgt
    14761 cgcctcatta ggtcgctgat gtgcgccagt acgagcatgc tcgtcccctc gttgacctaa
    14821 tggagtctgt tcatctgggc attacctcta atgggagggc gatgatctcc cgttagatga
    14881 gaagccggag agggaacgcg ccgcacgaaa ccggaaaagg gctggccgca ggagaggcgg
    14941 caggtcacga tggccgcatg ctgagcaccc ttctcgcctt cctcggcgcc tgcactctga
    15001 tcgccgcatc gcccggcccg agcaccgtgc tgatcatcaa gcggtcgctg cgcagcaggc
    15061 ggtccggctt cctgaccgtg ctcggcaacg agaccggcgt cttcgtctgg ggcgtcgtcg
    15121 ccgcgttcgg cctcaccgca ctgctcgccg cctccgagat ggcgtacgac atcatgcgga
    15181 tcgtcggcgc cgccgtgctc atcgccttcg gcgtccagac gctgtggcag gcgcgccgct
    15241 ccaagggagc cgtggacggc ggctgggagg acgcggagaa gagcggctgg gcctcctacc
    15301 ggggcgggct gctgctcaac ctcgccaacc cgaaggcggc catcttcgcg atgtccttcc
    15361 tgccgcagtt cgtgcccgag ggcgccccgc atctgcccac catggtcggt ctcgcagcgc
    15421 tctgggcggt ctacgaggtc ggctactacg gcctgtacgt gtggttcgtc ggccggatga
    15481 aggccgtgct gtcccggacc ggcgtacgcc gacgcctgga gcaggtctcc ggaggcgtgc
    15541 tgctgctcct gggcgcccgc ctcgccctgg agagctgaca cgcggccgcg gtaaccggct
    15601 cgcgcgcgcc tccccggaag ggcaggatgc tgcccgtagc cccctgggga actgcggaca
    15661 gacggaggca tggatgaccg gcacgcccgc gcccttcacc gccgacgact acgaggcacg
    15721 catgcggcgc gcggccgagg cagccgcgga cgccgggctc gccggcgtcc tggtggcgcc
    15781 agggcccgat ctggtgtggc tgacggggta tcggccggtg gagaccgagc ggctcactct
    15841 gctggtgctg agggcaggag aggatccggt cctggtcgtg cccactctgg aggcgcccga
    15901 cgcggccaag gcgaccggcg cgcccgcact gactctccgc gactggacgg acggcaagga
    15961 cccgtatgag gcgaccgcct ccctccttgc ccccgaggga cgcttcggcg tcagcgacaa
    16021 cgcctgggcc ctgcatctgc tcggcctcca gaagcggctg ccggactcgc gccacgtcgc
    16081 cctcaccgag gccctgccga tgctgcgggc cgtcaaggac gcggccgaac tggagcggtt
    16141 ggcggccgcg ggagcggccg cagacgcaac gttcgaggag atccggaggg ttcccttcgt
    16201 cggccgcagg gaggccgacg tggccgccga catcgccgat ctgctgcggc ggttcggcca
    16261 ctcccaggtc gacttcacca tcgtcgcctc ggggccgaac ggcgccaacc cgcaccacga
    16321 ggccgaggac cggatcatcc agcgcggcga catggtcgtc ctggacttcg gcggcctcaa
    16381 ggacggctac ggctccgaca cctcccgcac ggtccacgtc ggcgaaccgg acgacgagga
    16441 gcgcaaggtg tacgacatcg tgcgcgcggc ccaggaggcg gggttccgcg cggtgcggcc
    16501 gggagtggcg tgccaggacg tcgaccgggc ggcccgcgag gtgatcaccg aggccggcta
    16561 cggcgagtac ttcatccacc gcaccgggca cggcatcggc gtcaccaccc acgaaccgcc
    16621 ctacatgatc gagggcgaac agcagcccct cgtgcccgga atgtgcttct ccgtggagcc
    16681 gggcatctat ctgcccggcc gcttcggggt gcgcatcgag gacatcgtga cggtgaccga
    16741 ggacggcgga cgccgcctca acaccacctc ccgtgaactg gtgatcgtcg actgaccgac
    16801 catcggcagc attccccaag gccccaaggc cccaaggccc ccaacgacaa cggcgcgacc
    16861 atgacccagg caccgacacc gagcgcggac accgtccgcc gactggtccg ttcgctggtc
    16921 gccgacggcc ttgcggcggg agcgggaccc gacgtccggc ccgtcgccga gggcggtgag
    16981 cactccacct ggtgggtcgg cacgcgccat gtgctgcgac tcgcccagga ccgcgacgcc
    17041 tccgtactcc agcgtcgcga actgcggttg cgcgaccttg tccgtccgca catcggagtc
    17101 ccggtcccgg tgagtgtcgc gcacggcgaa tgggcgagcg gactgagctg caccctggac
    17161 accaggctgc ccggcgtctc cggcgagaag caggctgtct cggccgtcgg tgaggcagac
    17221 ctggcgggac tgctcacggg gctgcgcgaa gtgccggtac gccaggccga ggcgctcggc
    17281 gtaccgcgcg ccgcgccgcg ctccctggag gagctgcgga cggccgccgc gcacgcggcc
    17341 gaggaactcg ccgccgccga ggagttcgac cccgcccgcc tggcccagct caccgcgccc
    17401 gcggccctcc aactcgccgc gcagcccgcc gcggcgatcc tcgtgcacca cgacctcaag
    17461 ggcgaacacc tcatggtcag cgccgacggc cgggtacgcg gcgtcctcga ctgggccgac
    17521 gcggtgatcg gcgaccccgc cgaggacatc gccgggctcg cgatcgccgt cggcgccccc
    17581 gcggccgtac gcgccgccac gctcgccggc tacggccccc gtccctgcct gcgcggcctg
    17641 tggctgtccc gctgcgacac cgtgatccgc ctcgccgatc gccttcatgg ccgccgcgac
    17701 gacagtcccg tcccgctgct ggagacacaa ctgcgccgcg cctgggaggc gatcctgctg
    17761 gaacgggtca ccgatctgcg ggacgggctg gacgagacgc cgtaggtgag ggggcctggc
    17821 cggagggctg ggccggggcc gcgcgggagg cgtcatgttt ggtcgcgcgt cgcatgctgt
    17881 gcctgggcgc cgcacgccgt ccgtggcacc gccgacggcg agcgcctcac gcctgcgtca
    17941 gcaccacgca cgactcgccc ggcaccctca acaccccgtc cccgtccggc gcttcgacgg
    18001 gctcccaggc ggccagcacg cgcgcgtggc ggatgccgag agggattgcc gcggtctcct
    18061 tggcgagatt gacagccacc cggacgtcac cgcgccgcag agccagccag cgggcctgcg
    18121 cgtcgtgggc gactctgacc gccgcgagat cggggtccga gaggtcggcc tgacggcggc
    18181 gcagggcgat caggtcgcgg taccaggcca gtacgcgcgc gtggactgcc ttttcgggtt
    18241 ccgaccagtc gaggcaggag cggtcccggg tcgccgggtc ctgcgggtcg gggacgtcct
    18301 cctcggccca gccgtgcgcc gcgaactcac ggcgcctgcc ccgccgtacg gcctcggcga
    18361 gctcgggatc ggtgtggtcg gtgaagaact gccagggcgt gcccgcggcc cactcctcgc
    18421 ccatgaagag catcggcgtg aagggcgcgg tgagcgtcag cgcggcggcg caggccagca
    18481 gcccggggga gagggaggcc gagagccggt cgccctgggc gcggttgccg atctggtcgt
    18541 gggtctgggc gtagcccagc aggcggtgtg ccgagacgcg ggtgcggtcc agcgggcggc
    18601 cgtgagagcg cccgcggaag ctggagtacg tgccgtcgtg gaagtagccc gacgtaatcg
    18661 ttttcgccag cgccgtgaac ggggcgcgtg cgaagtccgc gtaatagccc tgtgcctcgc
    18721 cggtcagcgc ggtgtgcagc gcgtgatgga agtcgtcgtt ccattgggcg tgcatcccga
    18781 gaccgccctc ctcgcgcgga gtgacggttc gagggtcgtt cacgtcggac tcggcgatca
    18841 ggaagagcgg ccggccgagg tcgtcggcga gcgcgtccac ggccgtcgag agctgctcca
    18901 ggaagtgcac cgcgcgcgtg tcgcgcagtg cgtgcaccgc gtccaggcgc agcccgtcga
    18961 gccggtagtc gcgcagccac gccagcgcgc tgccgacgaa atacgcgcgc acctcgtccg
    19021 aaccgggcgc gtccaggttc acggcggagc cccagggcgt ctggtgggtg tccgtgaagt
    19081 acggcccgaa cgcgggcagg tggttgccgg aggggccgag gtggttgtgc acgacgtcga
    19141 ggacgacacc cagaccgact tcgtgcgccc ggtcgacaaa gcgcttcagc gcctcgggac
    19201 cgccataagg ttcatgcacg gcccacggcg agacgccctc gtacccccag ccgtgccgcc
    19261 ccgggaaggg gcacaacggc atcaactcga cgtgggtgac gcccagttcc gccaggtggc
    19321 cgagtcgctc ggcggccgcg tccagtgtgc cctcgggcgt gtacgttccc acgtgcagct
    19381 cgtacaggac cgcgcccggc agcgggcgtc ccgcccattc ggtgcgccag tcgtagcgcc
    19441 cctggtcgac caccgcactc agcccgtcgg gaccgtccgg ctggcgccgc gagcggggat
    19501 cgggcagcac ggggccgtcg tccaccgcga acccgtaccg cgtcccgtcc tgcgcgtccg
    19561 cgtcacctgt ccaccacccc gtacgctccc gatcgcgctc caacgcgcgc gtggcgcccg
    19621 cgcagtggag cgtcacccgg tcggcctgcg gtgcccacac atcgaaccgc acagacggtt
    19681 cccccttgtc agctcaccgt gacgtagctt gtccatggtg cttcacatga gatcaattcg
    19741 ctttcgaatc cacccttttg ccgcgtgttt gccgccctct tgtcacgcgg aacgctccgt
    19801 ccggccgcag cggccgtttc cgtgttttct ggacaccccg ctctcgctgc ccgacaatcg
    19861 ccagggtgac gtcgtctttc gagttccaca cgtaccccgc gcggctgtcc gacgcggagc
    19921 gcgaccgggc gctcaaggcg ctccgtgacg gcgtcgccct cggtcgcctc tcgcacgaca
    19981 cgttcatccg acgcatggag ttggcgctcg ctgcccgcag gtccgacgaa ctcgccgtgc
    20041 tcacggccga cctgcccacc gagggccgct ggtcgaagct ggtgttcggc actgtggaag
    20101 cggtctccgg cttcaccgta cgagtgcgca gggcttggca ggccgagcgg ctcccgaagt
    20161 tgttgctgcc ccatccgggc agcctgtacc cgctgcgcat cggtcgtgac cccgccagcg
    20221 gactgcggct caatcacgag acggtgtccc gggtacatgc cgaactgagc cggcagggtg
    20281 gcgtgtgggt gctgcgcgac ctgggctcga cgaacggcac gaccgtcaac ggacggcgcg
    20341 tcatcggcgc cgccgtcgtc agggacggcg atcagatcgg cttcgggcgg atgatgttcc
    20401 gcctcgcgtc ggagtgaacc gtggcgttgc ggctgaacgg tggcgttgcg gctgaaccac
    20461 ggcgttgcgg gctcgcggcg gagcgagtcc tccgccctgt gtcggaacga ttcctgatga
    20521 tccgccttgc gtgggagcga ctcctgatga tcggccttgc gtgcgagcga ctcctgatga
    20581 tcagcctggc gtcggcgcga gtctgacgtt ccgtttcgcg tcggacagcc ccggtcccac
    20641 cgacctctgg cctgggattc acccaccgct ttcctcgata tcccttgcgt tccgcagtgt
    20701 tgacgtaccc ccggagccgt gactgactgt gcgtacacca tgcacatcag gtgaaccgac
    20761 ggcaccacat aagtggaggt gtgccctgcc gccactcctc cgctacccga ctgtggacga
    20821 gctgggcgcc cgtgcggccg cgctcgtcgc ccgccgtccg agggacgccc ggctgcgccg
    20881 cgtgggcacc tcgcgggcgg ggacgccgtt gtggctgttg tccgtcggac acggcactcg
    20941 ccaggtcctt gtcgtcgcgg gaccgcacgc caacgaaccc gtcggcggtg ccacggccct
    21001 gcgcctcgcc gagcgggcgc tcgccgaccc ccggttgacc gagggggcgg acgccacctg
    21061 gaacctgctg ctgtgcctcg atcccgacgg ctcgcgccgc aacgaggcct ggctgtcggg
    21121 cccgtacacc ctcggccagt acttccggca cttcttccgg cccggcttcc tggaacagcc
    21181 cgaatggctg cccgagggcg cggacggggc caccctcccg gagacccgcg ccctcctcga
    21241 cctccaggac gaactgcggc cctttttgca gtgctccctg cacggcgtcg acgtcggcgg
    21301 cgccttcgtc gagctgaccc gcgaactgcc cggcctcgcc cagcgcgtcg cacacaccgc
    21361 tgcgcgcctc ggtatcccgc gcgagctcgg cccgtacgac accctgtact ggccggcgct
    21421 ggggcccgcc gtctaccgca tcccgccgcc gcgcaggggc ggcctggccg ccgccatcac
    21481 ggaggcggcg gtcgagtcca cctggttcca cccgcactcc tacggcacgg tgacggcggt
    21541 cgtcgaagcc cccatgtggg gcgtcgcggc cgtggaggac gccacgcggc ccgccgacgc
    21601 cgacgcgatg ctgcgcacca tcagccgcac gctgcgccgc gacacaggac tcctggaggg
    21661 catcctcgcg cgcgtgcgac ccagcctcgg cgcctccccg gacgtggcct gcctcctcgc
    21721 gcccgtcgac gactatttac tggtcggccc cggactcgcc gactcgtggg accccgacgt
    21781 gtacgacgcc ggtgcacgcc ccctgccgcc gctcgacacc gctcgtctga cggcactgcg
    21841 cctcgcgggg cgccgggttg cgctgcgcac ggccgggctg ctccaccagc tcgtgtccgc
    21901 ctccgggcac gacccgtgcg gcgtgcagcc ggagctcgac cggctcctcg acgagtggtg
    21961 cgccgactac cgcgaaggct gcggggcacg ctggatccct gtcgcccgtc aggtcgagta
    22021 ccaggcgcgt gtggtgctcg cctcgttcga actcgccggg cggcacgcgc ccgtgcgctc
    22081 ccgttcgggt gagtccggat ggggttcgga ggccacggtg ccgatgcatc tggaatgacg
    22141 aaatccgttc cggcgaagac cgttccggcg aagaccgttc cggcgaagac ggttccggcg
    22201 aaggccgt
//
