LOCUS       NZ_BMMJ01000025        14550 bp    DNA     linear   CON 09-SEP-2024
DEFINITION  Micromonospora yangpuensis strain CGMCC 4.5736 sequence25, whole
            genome shotgun sequence.
ACCESSION   NZ_BMMJ01000025
VERSION     NZ_BMMJ01000025.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Micromonospora yangpuensis
  ORGANISM  Micromonospora yangpuensis
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 35654)
  AUTHORS   Sun,Q. and Zhou,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 133X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014645775.1-RS_2024_09_09
            Annotation Date                   :: 09/09/2024 04:34:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,914
            CDSs (total)                      :: 5,857
            Genes (coding)                    :: 5,698
            CDSs (with protein)               :: 5,698
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 20 of 159
            Pseudo Genes (incomplete)         :: 144 of 159
            Pseudo Genes (internal stop)      :: 5 of 159
            Pseudo Genes (multiple problems)  :: 9 of 159
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:15:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 21104
            Orig. end                         :: 35654
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMMJ01000025.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..14550
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..14550
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..14550
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10282](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10282)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     gene            90..1097
                     /locus_tag="IEY64_RS29105"
                     /old_locus_tag="GCM10012279_58880"
     CDS             90..1097
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013284886.1"
                     /locus_tag="IEY64_RS29105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_58880"
                     /product="nitroreductase family protein"
                     /protein_id="WP_091435794.1"
                     /sec_met_domain="PF00881 (E-value: 1.3e-09, bitscore: 29.3,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPQTPATQRPLTIALAEAAAMAGHAPSVHNTQPWRWRVLPDALE
                     LRTASQRRLAATDPEGRLLALSCGAALHHARVALRAEGWTSVVQRSPDPADPELLARLT
                     DLRRGAADPPAMRLVQCMQVRHTDRRPVSADPVPADQLTEIVQAASGEGARLQLLDRDQ
                     VLELAATASHAGTVEADDPQLREELAYWTSRTSGAGLPPEVLPDQAPQTTVPGRDFGRP
                     GTLPVGPGHDRAAAYALLFGDEDEPESWLRAGEALSAAWLAATRLGVSVVPLSGVVEVP
                     GTRQILRQLLAGLGYPYLVLRLGLADPAHAGPPHTPRLAVEQTVDTSAVRDAQR"
     gene            1320..2948
                     /locus_tag="IEY64_RS29110"
                     /old_locus_tag="GCM10012279_58890"
     CDS             1320..2948
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019871404.1"
                     /locus_tag="IEY64_RS29110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_58890"
                     /product="GAF domain-containing protein"
                     /protein_id="WP_091446195.1"
                     /transl_table=11
                     /translation="MLDRVGEVVTSRERLRALLDAVVGIGTDLDLRSTLQRIVGSACEL
                     VGARYGALGVIGGDRSLHDFITHGIDAELHARIGDLPHGRGVLGLLIDEPRPLRMPDIT
                     RHPGSYGFPAHHPPMHSFLGVPVRIRDQVFGNLYLAEKQGAAEFTEDDEEIVVALAAAA
                     GVAIENARLYALAHRRERWLAATAEITSVLLGEVRRTDALTLVARRAREVAEAELAVVL
                     LYDEDAQQFTVEVVDGADEQARALVGAVLPAAETTFAGPVTERRHAQLANLAEAAPWPV
                     PVAAGPAVLSPLAAADTLHGVLLIAHAPDHGGATDDDVALLGSFAGQAALAMERARGQE
                     ERELLVVLEDRERIARDLHDVVIQRLFATGLHLQSAVPISTRPEVASRINAAVDDLDAT
                     IRDIRRTIFELRTPMSAALRTEIREAVAEAAALLGHRPVVELTGPIDSAVPDEVRPDLT
                     AVLREALTNAVRHARCTRLTVAVSVAAGRLTVTVSDDGTGMDPAAARSGLVNLRQRAHR
                     HGGEFTIDPVTPHGTSLRWSVPLSA"
     gene            complement(3040..3678)
                     /locus_tag="IEY64_RS29115"
                     /old_locus_tag="GCM10012279_58900"
     CDS             complement(3040..3678)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015622799.1"
                     /locus_tag="IEY64_RS29115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_58900"
                     /product="response regulator transcription factor"
                     /protein_id="WP_091435792.1"
                     /transl_table=11
                     /translation="MIRVFLLDDHEVVRRGLADLLTSGGDIEVVGESGSATEATRRIPA
                     LRPDVAILDARLPDGNGIDVCRDVRAVDSSIRGLILTSYEDDEALFAAIMAGAAGYVLK
                     QIRGTDLVDAVRRVAAGQSLLDPAITTRVLDRIRSGVEQPRELQSLTEQERRILEYVAE
                     GLTNREIAGRMFLAEKTVKNYVSSVLAKLGLERRTQAAVLATRLLGKRP"
     misc_feature    3903..3914
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.89"
                     /tool="antismash"
     gene            4004..4978
                     /locus_tag="IEY64_RS29120"
                     /old_locus_tag="GCM10012279_58910"
     CDS             4004..4978
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018740067.1"
                     /locus_tag="IEY64_RS29120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_58910"
                     /product="nitroreductase family protein"
                     /protein_id="WP_091435789.1"
                     /sec_met_domain="PF00881 (E-value: 2.8e-11, bitscore: 34.7,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESGFGVGQLRAAARDAVRAPSMHNSQPWRFRLREGGIEVAVDPD
                     RRLPAADPSGWAARIAGGAALFNLRLSLAVAGTPARVRLRPYPGEPDVLARLVPDVPRA
                     PTPAQRSLHAAVARRFSHRAPFWPNPVPAEARWRLVEAARAEQGWLELVIGVSAVNAFA
                     ALAQSAHRVLDRDRAYRDELAGWVRGGPAPDGVPAAAGGPVAQPQDLLPSRAFGVRERA
                     PGRDFEPEPLVAVLGAAGNTATDQVVAGQALQRVLLTATDAGLAVSLLSQPIEVPAARE
                     ALRLSLGRFGTPQMVLRVGYGQPGWPVGRRDVEEFLDLPVRRR"
     misc_feature    complement(5047..5060)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 17.82"
                     /tool="antismash"
     misc_feature    complement(5097..5112)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.53"
                     /tool="antismash"
     gene            5248..7989
                     /locus_tag="IEY64_RS29125"
                     /old_locus_tag="GCM10012279_58920"
     CDS             5248..7989
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012271.5"
                     /locus_tag="IEY64_RS29125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_58920"
                     /product="fibronectin type III domain-containing protein"
                     /protein_id="WP_139135630.1"
                     /transl_table=11
                     /translation="MLVAGVIAGSLVASAITTPTNAAARSPGRTSPVAAQQAAPPQAAP
                     PQAAAAPAPLVEKAKPVKPAAPARPKAAKKGTTAVVTWKAPKDNGNKITEYVVTSYRDG
                     RKAATKAFDAKQTSRKLTLPSAKGAWTFTVAAKNTAGVGPASKRSAPPKLLALPSAPTI
                     RAVTADVTTAVISWSPPASDGGSPITNYLIFPYIGGVKQASQTVPASPLTATVGGLTAG
                     ITYTFTIAALTSQGLGPESAPSHPVVPNESPWVFWNGNNAEVGVAYSQNVDVSRGQAPW
                     TFSITYGALPPGLTLNPNTGLIAGIPTTAGSFAFVVRVVGSAGRIGSRLITISVTPAPN
                     IVIPAVPLGEVNAPYSLRPTVVGGVAPYVWSLASGVLPPGLSIDPNTGEISGRPTTAGT
                     FGVDLRVTDAAGLSDVTQIRIVIQPQTVVTLTASASSVNFDSPVTFTANLGPGEAEGTV
                     TIFDRQRTGVTVNLGTQTVSFNRATFTLKLPAFGLNQVFVDFDSTITNGESVSNTVPVQ
                     VNGVPGQLLIDQFRQSGIANTPSQFDQYVVLYNNTSIPMQLPGIKVEAPGGVVIEIPNT
                     ATTIGPRVGYLIGTARYNVAFPTIPADLLVPTLGPVPNTGGTGLRLRVPDAAGTITDAA
                     GSTPGWSTGTPLPAFTSPPTVQNAWVRLRVSGTPQDTRDNRTDFRLVANVIGPVNGVPS
                     TLGSPSPLRQFGPFEQSNILQTTLLDPTKASNAAPNQQIIDATPTSPKRLIIRRAITNR
                     GVTPATLVRLRISTLSQVNGAPIPGTPTPPNPAELRAVNPTTPTETFTVGGRTVTVQNL
                     DLDPPSVDPPGGGLSSTLTAQLPLGGLPPGGTVYIALVFEVDKGGTFWVGWDVEAIGGG
                     PVTPPGLAATAAVTPKTQKAAKKAAAQRAKSQQLTNVRGSTR"
     gene            8073..8903
                     /locus_tag="IEY64_RS29130"
                     /old_locus_tag="GCM10012279_58930"
     CDS             8073..8903
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY64_RS29130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10012279_58930"
                     /product="hypothetical protein"
                     /protein_id="WP_175440486.1"
                     /transl_table=11
                     /translation="MPVRSAYGLHIRGLDGVTELTATAYPPAGSRPVTVRQRDTEAPEP
                     VPLDADRVVRPLTDGRTLELDRRLRTATFYGPPLDPAVLAHPYLAPVAVICNRWAGRET
                     FHAGAFGLDGRAWVVPGGRTAGKSSLLAALAARGVPVLTDDIAVLDGDQVLAGPRCVDL
                     REPVPGVALPTRGVRDGSRLRIALPAGPHRLPLGGWLFLRWGDGPALTPLGPTELLARL
                     AALRSLPELPSDATRLLGLAGVPAYELTRPRDWTALDATHRLLTATLTPVGAAR"
     gene            8945..9949
                     /locus_tag="IEY64_RS29135"
                     /old_locus_tag="GCM10012279_58940"
     CDS             8945..9949
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF026257.5"
                     /locus_tag="IEY64_RS29135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_58940"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_175440485.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 1.4e-20, bitscore:
                     64.7, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTANAASGGAASGSAASGSAASGSAASGSAASAGLALRCLALDSA
                     ALATSDLLRQAGVPSVLLKGAGLAHRLGVERLYGDVDLLVAPASFAAAQTALAAAGYRP
                     REDTALHRRWGLWHEQTWSVPGPVPFVLDLHRGFARVGDADELWTVLYSGAEPVTLAGG
                     TVLVPDEAGCALLVALHAASPGGSARPLADLARALDVLPLRVWPAAAALAERCAALSAF
                     TVGLRLLPVGAAVAAGLGLPATGGRSYQLAAQRASPLAINLADLDELSRWRRLRRLATL
                     ALPTPDRLRLADPLAGHGAGTLFLAHLRRYRRHARALPRALRELRAARRHPEG"
     gene            complement(10001..10282)
                     /locus_tag="IEY64_RS29140"
                     /old_locus_tag="GCM10012279_58950"
     CDS             complement(10001..10282)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017239.5"
                     /locus_tag="IEY64_RS29140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_58950"
                     /product="PqqD family protein"
                     /protein_id="WP_175440484.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 9.2e-19,
                     bitscore: 58.4, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2.1e-14, bitscore: 44.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTETTTLYQVDAERVAWRTVGDEAVLLDVRNSVYFALDSWAVLL
                     WPHLVTGATAADLTAVLAAHAPVDPERAAADVRSFLAELDTADLLNRH"
     aSDomain        complement(10007..10243)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_IEY64_RS29140_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="8.60E-19"
                     /identifier="RREFam002.1"
                     /label="IEY64_RS29140"
                     /locus_tag="IEY64_RS29140"
                     /protein_end="92"
                     /protein_start="13"
                     /score="58.4"
                     /tool="antismash"
                     /translation="ERVAWRTVGDEAVLLDVRNSVYFALDSWAVLLWPHLVTGATAADL
                     TAVLAAHAPVDPERAAADVRSFLAELDTADLLNR"
     gene            complement(10279..11475)
                     /locus_tag="IEY64_RS29145"
                     /old_locus_tag="GCM10012279_58960"
     CDS             complement(10279..11475)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012936.5"
                     /locus_tag="IEY64_RS29145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_58960"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_175440483.1"
                     /sec_met_domain="Asn_synthase (E-value: 1e-14, bitscore:
                     45.8, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDLSLARPTAQDVACGIVLGQDPAAGPLTARLSAAGPPAAGPPA
                     VRPGPVPAPLVALEQAVLPALCRPPCLVSFSGGVDSALVLAIAARVARREGLPDPVPVT
                     WRFTDAPRAQESDWQDRVIAELGLGRHWRILSAGEDLDLVGPVAARLLDRYGQLHPPNR
                     HLHLPIIELARGGALLTGVGGDQILAGWRRRPGSLRARLSRLRHSVGRRAAREPDPFPW
                     LRPRVARELRRRFRAERRAEPHRLAGRVAWHLGRRDLTMTRASLTAVAADHDVLAVTPL
                     LDEGFAVALATHRGRWRSPSRRELLADLADADLPPLVVAPRRKATFDEVFFRAGTREFV
                     HGWDGTGVDETLVDPAALRREWTAWPVCPRTAALVHQVWLASRPAGTGPAQPIMEVPR"
     gene            complement(11468..12424)
                     /locus_tag="IEY64_RS29150"
                     /old_locus_tag="GCM10012279_58970"
     CDS             complement(11468..12424)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013245.5"
                     /locus_tag="IEY64_RS29150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_58970"
                     /product="ABC transporter permease"
                     /protein_id="WP_091435778.1"
                     /transl_table=11
                     /translation="MSSDLRAAPAHPPPEPSPAGPLAVGPAGTASRWAGTASRSAGVGS
                     RWAGAASAWAGGRTVLTLLRRDLSEHRGLGPPFLLDLAFGLVNLLVFRFVSQVVTLGPD
                     ADFTRSTSYFDFVAVGIVFLLVLQAGTVQVVTRLAGEQRAGTLELLTAQPVPRWALGLG
                     LAGYPFVFALLRAGLYLAVLGTFFGLHIGRADWVGVVVVAALGALCTLPFGLALAGLAV
                     AFGAGEPVARLLVVALSFLSGTYFPVSALPVAVRAFAEPLPTRIALDGLRHALTGGGWS
                     TAALALTGAAAVLLPLSAWIFDRALWLARRRGVLTRD"
     gene            complement(12480..12638)
                     /locus_tag="IEY64_RS29155"
                     /old_locus_tag="GCM10012279_58980"
     CDS             complement(12480..12638)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY64_RS29155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10012279_58980"
                     /product="lasso RiPP family leader peptide-containing
                     protein"
                     /protein_id="WP_139135629.1"
                     /transl_table=11
                     /translation="MNVSPDSTNDSAPVADYQRPHLRRLGTLAELTQGGFPGVTDADGQ
                     SGVLGSI"
     misc_feature    complement(12741..12755)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 15.88"
                     /tool="antismash"
     misc_feature    12759..12772
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.54"
                     /tool="antismash"
     misc_feature    complement(12787..12798)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     tRNA            complement(12802..12873)
                     /anticodon=(pos:complement(33943..33945),aa:Val,seq:gac)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="IEY64_RS29160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="GCM10012279_t00590"
                     /product="tRNA-Val"
     gene            complement(12802..12873)
                     /locus_tag="IEY64_RS29160"
                     /old_locus_tag="GCM10012279_t00590"
     tRNA            complement(12940..13012)
                     /anticodon=(pos:complement(34081..34083),aa:Gly,seq:gcc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="IEY64_RS29165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="GCM10012279_t00600"
                     /product="tRNA-Gly"
     gene            complement(12940..13012)
                     /locus_tag="IEY64_RS29165"
                     /old_locus_tag="GCM10012279_t00600"
     gene            13161..13406
                     /locus_tag="IEY64_RS29170"
                     /old_locus_tag="GCM10012279_58990"
     CDS             13161..13406
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013284878.1"
                     /locus_tag="IEY64_RS29170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_58990"
                     /product="DUF6458 family protein"
                     /protein_id="WP_091435775.1"
                     /transl_table=11
                     /translation="MGIGTSIFLLAVGAILTFAVNASVGGVDLDIVGWILMAAGVLGLI
                     MTAAVWGRRRQTVATAPAAEPVEYRVEERRDIVPPR"
     gene            <13742..14215
                     /gene="smpB"
                     /locus_tag="IEY64_RS29175"
                     /old_locus_tag="GCM10012279_59000"
                     /pseudo=""
     CDS             <13742..14215
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene="smpB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007071236.1"
                     /locus_tag="IEY64_RS29175"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_59000"
                     /product="SsrA-binding protein SmpB"
                     /pseudo=""
                     /transl_table=11
                     /translation="RQTGQQLVATNRRARHDYTILKTYEAGLVLAGTEVKSLRAGRVSL
                     VDAFAQERDGELLLHGLHIAEYGYGSWTNHQPRRTRKLLLRRVEIDRILERLRDGGLTL
                     VPLSMYFANGWAKVELALAQGRRSYDKRQALAERDANREIARAFGQHLKGRRR"
     misc_feature    complement(14326..14340)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.33"
                     /tool="antismash"
ORIGIN
        1 ggccccgccg accgaccatg gatgggcaac cccgcccccg gcaggtcccg gctggggcac
       61 gatgagaaaa acggagaggt cacagactga tgagccctca gacgccggcc acccagcgcc
      121 cgttgaccat cgcgctcgcc gaggccgccg cgatggccgg gcacgccccg tcggtgcaca
      181 acacccagcc gtggcggtgg cgggtgctgc cggacgccct ggagctgcgt accgcctcgc
      241 aacggcgact ggccgccacc gacccggagg ggcggctgct ggcgttgagc tgcggagcgg
      301 ccctgcacca cgcccgggtg gcgttgcgcg ccgagggctg gacgtcggtg gtgcagcgca
      361 gccccgatcc ggccgatccg gagctgctgg cccggctgac cgacctgcga cgcggcgcgg
      421 ccgacccgcc ggcgatgcgc ctggtgcagt gcatgcaggt ccggcacacc gaccggcggc
      481 cggtcagcgc ggatccggtg ccggccgacc agctcaccga gatcgtccag gccgcctccg
      541 gggagggcgc ccggttgcag ctgctggacc gggaccaggt cctggagttg gcggcgaccg
      601 cctcgcacgc cggcacggtc gaggccgacg atccgcagct gcgggaggag ctggcctact
      661 ggaccagccg tacctccggt gccgggctgc cgccggaggt gctgcccgac caggcgccgc
      721 agaccaccgt gccgggccgc gacttcggcc gccccggcac cctgccggtc gggccggggc
      781 acgaccgggc ggccgcgtac gcgctgctct tcggggatga ggacgagccg gagagctggc
      841 tgcgggccgg tgaggcgctc tcggccgcct ggctggccgc gacccggctc ggggtgtcgg
      901 tggtgccgct gtcgggcgtg gtggaggtgc cgggcacccg gcagatcctg cgtcagctcc
      961 tggccggcct cggctacccg tacctggtgc tgcggttggg tctggcggac ccggcgcacg
     1021 ccgggccgcc gcacaccccc cggctcgccg tggaacagac cgtcgacacc tcggcggtac
     1081 gcgacgcgca gcgttgaacc ggaccggcgt cgcccgtcac gcggcccgga ccggcgacgc
     1141 cccgccacgc ggcccggacc ggcgacgccg tcgctcgggc gggccgcgac gagccggcgg
     1201 tgggcggtag cattcggcgg gtggccgcca gcgcaccccg ttccggcaac gaccagacga
     1261 tcccctcgct cgggctgagt ccgctgtcgc gggtacgcct cgacgagctg ctccaggaga
     1321 tgctggaccg ggtaggcgag gtggtgacca gccgggagcg gctgcgggcc ctgctggacg
     1381 cggtggtcgg catcggcacc gacctggacc tgcgcagcac cctgcaacgg atcgtcggat
     1441 cggcctgtga gctggtcggg gcccgctacg gcgcactcgg ggtgatcggc ggcgaccggt
     1501 cactgcacga cttcatcacc cacggcatcg acgccgagct gcacgcccgg atcggcgacc
     1561 tgccgcacgg ccggggcgtg ctggggctgc tcatcgacga gccccgcccg ctgcggatgc
     1621 cggacatcac ccggcacccc gggtcgtacg ggttcccggc gcaccacccg ccgatgcaca
     1681 gcttcctcgg cgtgccggtc cgcatccgtg accaggtctt cggcaacctg tacctggccg
     1741 agaagcaggg tgcggcggag ttcaccgagg acgacgagga gatcgtggtg gcgttggccg
     1801 ccgccgccgg ggtggccatc gagaacgccc ggctgtacgc gctggcccac cgccgggaac
     1861 gctggctggc cgccaccgcc gagatcacct cggtgctgct cggcgaggtc cggcgtaccg
     1921 acgcgttgac cctggtcgcc cggcgggccc gggaggtcgc cgaggccgag ctggcggtgg
     1981 tgctgctcta cgacgaggac gcccagcagt tcaccgtgga ggtggtcgac ggcgccgacg
     2041 agcaggcccg cgcgctggtc ggggcggtgt tgccggccgc cgagaccacc ttcgccggcc
     2101 cggtcaccga acgccgccac gcgcagctgg ccaacctggc cgaggcggca ccctggccgg
     2161 tgccggtcgc cgccggcccg gccgtgctct ccccgctggc cgccgccgac accctgcacg
     2221 gggtgctgct gatcgcccac gcccccgacc acggtggcgc caccgacgac gacgtggccc
     2281 tgctgggcag cttcgccggt caggcggcgc tggccatgga acgggcccgg ggccaggagg
     2341 aacgggagct gctggtggtc ttggaggacc gcgaacgcat cgcccgggac ctgcacgacg
     2401 tggtgatcca gcggctcttc gccaccggtc tgcacctgca gagcgccgtg ccgatcagca
     2461 cccgccccga ggtggccagc cggatcaacg ccgccgtcga cgacctggac gccaccatcc
     2521 gcgacatccg ccggaccatc ttcgagctgc gtaccccgat gagcgcggcg ctgcgtaccg
     2581 agatccggga ggcggtggcg gaggccgccg cgctgctggg ccaccgcccg gtcgtggagc
     2641 tgaccggacc gatcgacagc gccgtgccgg acgaggtccg acccgacctc accgccgtgc
     2701 tgcgcgaggc cctcaccaac gcggtacgcc acgcgcggtg cacccggctg acggtggcgg
     2761 tgtcggtggc cgccggccgg ttgacggtca cggtcagcga cgacggcacc ggcatggatc
     2821 ccgccgccgc ccgcagtggc ctggtcaacc tgcggcaacg ggcgcaccgc cacggcggcg
     2881 agttcaccat cgacccggtc accccgcacg gcaccagcct gcgctggagc gtcccgctgt
     2941 cggcctgacc gggcagctca gtgggcgtct gccgccggtc aggcggtgac cgggcagctc
     3001 agtgggcgtc tgccgccggt caggcggtga tcgggcagct cagggacgtt tgccgagcag
     3061 gcgggtggcg aggacggcgg cctgggtacg ccgttccagg ccgagcttgg ccagcacgct
     3121 ggagacgtag ttcttcacgg tcttctcggc caggaacatc cgtccggcga tctcccggtt
     3181 ggtgagcccc tcggcgacgt actccaggat ccggcgttcc tgctcggtca gtgactgcag
     3241 ctcccggggc tgctcgacgc cgctgcggat gcggtccagc acccgggtgg tgatcgccgg
     3301 gtcgagcagc gactgcccgg cggcgacccg gcggaccgcg tcgaccaggt cggtgccccg
     3361 gatctgcttg agcacgtacc cggcggcacc ggccatgatc gcggcgaaga gcgcctcgtc
     3421 gtcctcgtag gaggtgagga tcaggccccg gatcgacgag tcgacggccc ggacgtcccg
     3481 gcacacgtcg atgccgttgc cgtcgggcag ccgggcgtcg aggatcgcca cgtccggccg
     3541 gagcgcgggg atgcggcggg tggcctccgt cgccgacccg gactccccca ccacctcgat
     3601 gtcgccaccg gaggtgagca ggtcggcaag gccacggcgg acgacctcgt ggtcgtcgag
     3661 aaggaacacc cggatcatcc ctcgtttcta ccccctcgcc ccggatcgcc gcagggccga
     3721 aggtcccgtc acccaccgac cgtggtcgtg ccccgctccc ccggggcggg ccccactctc
     3781 ccgggatggg ccccgctctc ccgggatggg ccccactccc cccggggtga ggccgacccg
     3841 ctcccccggc gtgaggccgg ccccgctcca tcggggtggt gagaaggggg cccttctata
     3901 ccgaaagcgt taacaggggg cccttccttt caggtcgttg ggccctgacg ggggggcggg
     3961 gggtgggggg agggtgggtg gtaggtcggg agggggcggg gtcatggaga gtgggttcgg
     4021 ggtcgggcag ttgcgggccg ccgcccggga tgcggtccgc gcgccgtcga tgcacaacag
     4081 tcagccgtgg cggttccggc tgcgcgaggg cgggatcgag gtggcggtcg atccggaccg
     4141 gcggttgccg gcggccgacc cctcgggctg ggcggcgcgg atcgccggtg gggcggcgct
     4201 gttcaacctg cggttgtcgt tggcggtggc cggtaccccg gcccgggtgc ggttgcggcc
     4261 gtacccgggt gagccggacg tgctggcccg gctggtgccg gacgtgcccc gggcgcccac
     4321 cccggcgcag cggagtctgc acgcggccgt ggcccgccgg ttcagtcacc gggcgccgtt
     4381 ctggccgaat ccggtgccgg ccgaggcgcg ttggcggttg gtggaggcgg cgcgggccga
     4441 gcagggttgg ctggagctgg tgatcggggt gagcgcggtg aacgccttcg ccgcgctggc
     4501 gcagagcgcc caccgggtgc tggaccggga ccgggcctac cgggacgagc tggccggttg
     4561 ggtacgcggc ggtcccgccc ccgacggggt gccggctgcc gccggtgggc cggtggcgca
     4621 gccgcaggat ctgctgccca gccgggcctt cggggtccgg gaacgcgcgc ccggccggga
     4681 cttcgagccg gagccgctgg tggcggtgct cggtgccgcc gggaacaccg ccaccgacca
     4741 ggttgtcgcc gggcaggcgt tgcagcgggt gctgctcacc gccaccgacg ccgggctggc
     4801 cgtgtcgctg ctctcccagc cgatcgaggt gccggcggcg cgggaggcgc tccggttgtc
     4861 gctggggcgg ttcggcaccc cgcagatggt gctgcgggtc gggtacggcc agccggggtg
     4921 gccggtcggt cgccgtgacg tcgaggagtt tctcgacctg ccggtgcgcc ggcggtagtc
     4981 agggccggcg ggccgtcccg ggcggagtcg gcgtcggatg aaaatccggc acccgccata
     5041 cccccattga gctgggaaaa gtggtagaac agagtcaggt ttagatcgat ctgggcgaat
     5101 atcattcgct ttctccccac atcgactcgg ccaccggccg agcagttcgg cgtgcgccga
     5161 cgccgccgcc cgccgacgac tctgcaccgc caccaccccc agctcccgag aggtaggcac
     5221 tggatgcccc gaacgtcccg tttacgcatg ctggtagcgg gggtgatcgc cggttcgctc
     5281 gtcgcctcgg cgatcaccac cccgaccaac gccgcagccc ggtcacccgg ccgcacgtcc
     5341 ccggtggccg cgcagcaggc ggccccacca caggccgccc caccgcaggc ggcggcagcg
     5401 ccggccccgc tggtggagaa ggccaagccg gtcaagccgg ccgccccggc gaggccgaag
     5461 gccgccaaga agggcaccac cgccgtggtg acctggaagg ccccgaagga caacggcaac
     5521 aagatcaccg agtacgtcgt cacctcgtac cgcgacggcc ggaaggcggc gacgaaggcc
     5581 ttcgacgcca agcagaccag ccggaagctg accctgccgt cggccaaggg tgcctggacg
     5641 ttcaccgtgg cggcgaagaa cacggccggc gtcggcccgg ccagcaagcg ctccgcccca
     5701 ccgaagctgc tcgccctgcc cagcgcgccg accatccggg cggtcaccgc cgacgtcacc
     5761 accgcggtga tcagctggag ccctccggcc tccgacggcg gctcaccgat caccaactac
     5821 ctcatcttcc cgtacatcgg tggggtgaag caggcgtcgc agacggtgcc ggcctcgccg
     5881 ctgaccgcca ccgtgggcgg tctgaccgcc gggatcacct acaccttcac catcgccgcg
     5941 ctgacctccc agggcctcgg cccggagtcc gcgccgtcgc acccggtcgt cccgaacgag
     6001 tcgccgtggg tcttctggaa cggcaacaac gccgaggtcg gcgtggccta cagccagaac
     6061 gtcgacgtct cccggggaca ggcaccgtgg acgttctcca tcacctacgg cgccctgcca
     6121 cccgggttga cgctcaaccc gaacaccggc ctcatcgccg gcatcccgac cacggcgggc
     6181 agcttcgcct tcgtggtccg ggtggtcggc agcgccggcc ggatcggcag ccggctgatc
     6241 accatctcgg tcaccccggc gccgaacatc gtcattcccg ccgtcccgct gggtgaggtc
     6301 aacgcgccct actcgctgcg acccaccgtg gtcggtgggg tggccccgta cgtctggtcg
     6361 ctcgcctccg gcgtcctgcc ccccggcctg agcatcgacc cgaacaccgg tgagatcagt
     6421 ggccgaccca ccaccgccgg caccttcggc gtcgacctgc gggtgaccga cgccgccggg
     6481 ctcagcgacg taacacagat ccggatcgtg atccagccgc agacggtggt caccctgacc
     6541 gccagcgcca gctcggtgaa cttcgacagt ccggtcacgt tcaccgccaa cctcggcccg
     6601 ggtgaggccg agggcacggt gaccatcttc gaccggcagc gcaccggggt caccgtcaac
     6661 ctgggcaccc agaccgtcag tttcaaccgg gcgaccttca ccctgaagct gcccgcgttc
     6721 ggcctcaacc aggtcttcgt ggacttcgac tccaccatca ccaacggcga gtccgtctcc
     6781 aacacggtgc cggtgcaggt caacggggtg ccggggcagt tgctcatcga ccagttccgg
     6841 cagtccggca tcgccaacac gcccagccag ttcgaccagt acgtggtgct ctacaacaac
     6901 acctcgatcc cgatgcagct gcccgggatc aaggtggagg cccccggcgg cgtggtgatc
     6961 gagatcccga acaccgcgac caccatcggc ccccgggtcg gttacctgat cggcacggcg
     7021 cggtacaacg tcgccttccc gaccatcccg gcggacctgc tggtgccgac cctcgggccg
     7081 gtgcctaaca ccggcggcac cggcctgcgg ctgcgggtgc ccgacgccgc cggcaccatc
     7141 accgacgcgg ccggcagcac acccggctgg tccaccggca cgccgctgcc ggcgttcacc
     7201 agcccgccga cagtccagaa cgcctgggta cgactgcggg tctccggcac gccgcaggac
     7261 acccgcgaca accggaccga cttccggctg gtcgccaacg tgatcggacc ggtcaacggg
     7321 gtgccgtcca cgctcggctc gccgtcgccg ctgcgccagt tcgggccgtt cgagcagagc
     7381 aacatcctgc agaccaccct gctcgacccg accaaggcct ccaacgcggc cccgaaccag
     7441 cagatcatcg acgccacccc gaccagcccc aagcggctga tcatccgacg cgcgatcacc
     7501 aaccggggcg tcaccccggc gaccctggtc cggctgcgca tctccacgct cagccaggtc
     7561 aacggcgcgc ccatcccggg cacccccacc ccgcccaacc cggcggagtt gcgggcggtc
     7621 aacccgacca cgcccaccga gacgttcacc gtcggtggac ggacggtgac cgtgcagaac
     7681 ctcgacctgg acccgccgtc ggtggatccg ccgggcggcg ggctctccag cacgctgacc
     7741 gcgcaactgc cgctgggcgg cctgccgccc ggtgggaccg tctacatcgc cctcgtcttc
     7801 gaggtggaca agggtggcac cttctgggtc ggctgggacg tcgaggccat cggtggtggc
     7861 cccgtcaccc cgccgggtct cgccgccacg gctgcggtga ccccgaagac gcagaaggcg
     7921 gccaagaagg ccgccgcgca gcgggcgaag agccaacagc tgaccaacgt acggggcagc
     7981 acccgctgac ccgtccgacc agctgaccac cgggtggggg ccgacgtgcc cccacccggt
     8041 gctgtccacc gagagccagg tgaggaacga gcatgccagt cagatccgcc tacgggctgc
     8101 acatccgggg cctggacggg gtcaccgagc tgaccgccac cgcgtacccg ccggccggca
     8161 gccgaccggt gaccgtgcgg caacgcgaca ccgaggcacc ggagccggtg ccgctggacg
     8221 ccgaccgggt ggtccgcccg ctcaccgacg ggcgcaccct ggagctggac cggcggctgc
     8281 gcaccgcgac cttctacggc ccgccgctgg acccggcggt gctggcccac ccctacctcg
     8341 ccccggtggc ggtgatctgc aaccgctggg cggggcggga gaccttccac gccggggcgt
     8401 tcgggctcga cggccgggcc tgggtggtgc ccggtgggcg taccgccggc aagagcagcc
     8461 tgctcgcggc gctggccgcc cggggcgtac cggtgctcac cgacgacatc gccgtcctcg
     8521 acggtgacca ggtgctcgcc gggccgcgct gcgtggacct gcgggagccg gtgcccggcg
     8581 tggcgctgcc cacccgcggc gtgcgtgacg gcagccggct gcggatcgcc ctgcccgccg
     8641 ggccgcaccg gctgcccctg ggcggctggc tcttcctgcg ctggggcgac gggccggcgt
     8701 tgacgccgct gggcccgacc gagctgctgg cccggctcgc cgccctgcgt tccctgccgg
     8761 agctgccctc cgacgcgacc cggctgctcg gcctggccgg cgtccccgcg tacgaactca
     8821 cccgcccccg cgactggacc gccctggacg ccacccaccg gctgctgaca gccaccctca
     8881 ccccggtcgg ggcggcccgg tgaccgccgg caccggcggg cccctcccgc cggccgatgg
     8941 cccggtgacc gccaacgcgg cgagcggcgg cgcggcgagc ggcagcgcgg cgagcggcag
     9001 cgcggcgagc ggcagcgcgg cgagcggcag cgcggcctcc gccggtctgg cgctgcgctg
     9061 cctcgccctg gacagcgccg cgctggccac cagcgacctg ctgcgccagg cgggagtgcc
     9121 gagcgtgctg ctcaagggcg ccggcctggc ccaccggctc ggcgtcgagc gcctctacgg
     9181 cgacgtggac ctgttggtcg cgccggccag cttcgccgcc gcgcagaccg cgctcgccgc
     9241 cgccggctac cgaccccggg aggacaccgc cctgcaccga cggtgggggc tctggcacga
     9301 gcagacctgg tcggtccccg gcccggtgcc gttcgtgctg gacctgcacc gtggtttcgc
     9361 gcgggtaggc gacgccgacg aactgtggac cgtgctgtac tccggggccg aaccggtcac
     9421 cctggccggc ggcaccgtac tggtgcccga cgaggcgggc tgcgccctac tggtcgccct
     9481 gcacgcggcc agccccggcg gctccgccag gcccctcgcc gacctggccc gtgccctcga
     9541 cgtgctgccg ctgcgggtct ggccggcggc ggccgccctg gccgagcggt gcgcggcgct
     9601 gtccgccttc accgtcgggc tccggctgct gccggtgggc gcggcggtgg ccgccggcct
     9661 cgggctgccc gcgaccggcg gacggtcgta ccagctcgcc gcgcagcggg ccagcccgct
     9721 cgcgatcaac ctcgccgacc tcgacgagct ttcccggtgg cggcggctgc gccgactcgc
     9781 cacgctcgcc ctgcccaccc ccgaccgcct ccggctggcc gacccgctcg ccgggcacgg
     9841 cgcgggcacg ctgttcctgg cccacctgcg ccggtaccgc cggcacgccc gcgcgctgcc
     9901 ccgggcgctg cgggagctgc gcgcggcccg acgccacccc gagggctgag cggcacggcc
     9961 gtggtcagtg gcggtcgaac agccagtggc ggtcgaacgg tcagtggcgg tttagcaggt
    10021 cggcggtgtc cagctcggcc aggaaggagc gcacgtcggc ggcggcccgc tccgggtcga
    10081 ccggggcgtg cgcggccagc acggcggtca ggtcggcggc ggtcgccccg gtcaccaggt
    10141 gcggccagag caacaccgcc cagctgtcca gggcgaagta gacggagtta cggacgtcca
    10201 gcagcaccgc ctcgtccccg acggtccgcc aggccacccg ctcggcgtcg acctggtaca
    10261 gggtcgtggt ctcggtgttc acctcggtac ctccatgatc ggttgtgccg ggcccgtacc
    10321 ggccggccgg gaggccagcc agacctggtg caccagggcc gccgtgcggg ggcagaccgg
    10381 ccaggcggtc cactcccgac gcagcgcggc tgggtccacc aacgtctcgt ccacgccggt
    10441 gccgtcccag ccgtgcacga actcccgggt cccggcgcgg aagaacacct cgtcgaaggt
    10501 ggccttgcgg cggggcgcga cgaccaacgg cggcaggtcg gcgtcggcca ggtcggccag
    10561 cagctcccgc cgcgacgggg accgccaccg gccccggtgg gtggccaggg cgacggcgaa
    10621 cccctcgtcc agcagcgggg tcaccgcgag cacgtcgtgg tcggcggcga ccgcggtcag
    10681 gctggcccgg gtcatggtca ggtcacgccg gcccaggtgc caggcgaccc gcccggccaa
    10741 ccggtgcggc tcggcccgcc gctcggcccg gaaccgtcgg cgcagctccc gggccacccg
    10801 gggacgcaac caggggaacg ggtccggctc ccgggcggcc cgccgcccga cgctgtggcg
    10861 cagccggctc aaccgggcgc gcagcgagcc gggacgacgc cgccagccgg ccaggatctg
    10921 gtcaccgccc accccggtca acagcgcccc gccccgggcc agctcgatga tcggcaggtg
    10981 caggtgccgg ttcggcggat gcagctgccc gtaccggtcg agcagccggg cggcgaccgg
    11041 accgaccagg tccaggtcct caccggcgga caggatccgc cagtgtcggc ccagccccag
    11101 ctcggcgatc acccggtcct gccagtccga ctcctgtgcc cggggcgcgt cggtgaaccg
    11161 ccaggtcacc ggcaccggat cgggcagccc ctcgcgccgg gcgacccggg cggcgatggc
    11221 cagcaccagt gcggagtcca ccccaccgga gaagctcacc aggcagggcg gccggcacaa
    11281 cgccggcagc accgcctgtt ccagggcgac cagcggggcc ggcaccgggc cgggccgcac
    11341 cgcgggcggg ccggcagcgg gcgggccggc agccgacagc cgggccgtga gcgggccggc
    11401 cgccgggtcc tggcccagca cgatgccgca ggccacgtcc tgcgcggtgg gccgggcaag
    11461 agaaaggtca gtcacgggtg agcacccccc tgcgccgggc gagccacagc gcgcggtcga
    11521 agatccaggc cgacaacggc agcagtacgg cggcagcccc ggtcagggcc agcgccgccg
    11581 tcgaccaacc accgccggtc aacgcgtgcc gcagcccgtc cagggcgatc cgggtgggca
    11641 gtggttcggc gaacgcccgt accgccaccg gcagcgccga gaccggaaaa tacgtgccgg
    11701 agaggaagga cagcgccacc accagcaggc gggccaccgg ctccccggcg ccgaaggcca
    11761 ccgcgaggcc ggccaacgcg agcccgaacg gcagggtgca gagcgcgccc agggctgcga
    11821 ccacgaccac ccctacccag tcggcccgcc cgatgtgcag gccgaagaag gtcccgagca
    11881 ccgcgaggta gagcccggcc cgcagcaggg cgaagacgaa cgggtacccg gccaggccca
    11941 ggcccagcgc ccaccgtggc accggctgcg cggtcagcaa ctccagggtg ccggcccgct
    12001 gctcgccggc cagccgggtc accacctgga cggtgccggc ctggagcacc agcaggaaga
    12061 cgatgcccac cgcgacgaag tcgaagtagc tcgtcgagcg ggtgaagtcg gcgtcggggc
    12121 ccagcgtgac cacctgcgag acgaagcgga acaccagcag gttgaccaac ccgaaggcca
    12181 ggtcgagcag gaacggtggc ccgagaccgc ggtgctcgga caggtcccga cgcagcaacg
    12241 tcagcaccgt acggccaccg gcccacgccg acgccgcacc ggcccaccgc gatcccacac
    12301 cagccgaccg cgatgccgta ccggcccacc gcgatgccgt accggccggc ccgacggcga
    12361 gcgggccggc cggtgacggt tccggcggcg ggtgtgccgg tgccgcgcgg aggtcgctgc
    12421 tcatcggtgc accgacaggt cgacacccac agcagaccgc cgctggtggg gtcgtcggct
    12481 cagatcgagc ccaggacgcc ggactggccg tccgcgtcgg tcaccccggg gaaaccgccc
    12541 tgggtcagct cggccagggt gccgaggcga cgcagatgcg gccgctggta gtcggcgaca
    12601 ggcgcgctgt cattcgtcga atccggagaa acattcacga aaacccccat acgcataaaa
    12661 cggactaggc gaatcgtaat tgatccgggc gtcccgttgg gcgtttcacc acaccgagcc
    12721 cgcgcgacac gcggagcaca ctggcagaac gagaaaaaag aagagatgtt cggatccgcc
    12781 gacacggcat tcacttaccg gtgggcgata ctgggtttga accagtgacc tcttccgtgt
    12841 caaggaagcg cgctcccact gcgccaatcg cccgtgggca ccgacccggc gacgacggcc
    12901 gcgctcggca acggtcaccc cggtcagggg cataccacga gcggacgacg ggattcgaac
    12961 ccgcgaccct caccttggca aggtgatgcg ctaccagctg cgctacgtcc gcacgtcacc
    13021 ggccagcgcc agcgacgttg cgaactctac ccgacgacaa gatcagccga cggccacccc
    13081 cgcacccgga tggttgccca gctcaccggc ggggtagttg aactccccga cagcacatca
    13141 ccccctcgaa ggaggctgtc gtgggcatcg gaacgagcat tttccttctc gcggtcggcg
    13201 cgatcctcac cttcgccgtc aacgccagcg tcggcggtgt cgacctggac atcgtcggct
    13261 ggatcctgat ggccgccggc gtactcggcc tgatcatgac cgcggcggtc tggggccgcc
    13321 gccgccagac ggtcgccacc gctcccgccg ccgagccggt ggagtaccgg gtcgaggagc
    13381 gtcgggacat cgtcccgccg cgctgaccgg gttcgtcccc gagggcggcg gcccgtaccg
    13441 ccggtcgcct tcgccgcccg ccggacccgc cggacccgcc ggacccgccg gacccgccgg
    13501 acccgccgga cccgccggac ccgccggacc cgccggaccc gccggacccg ccggacccgc
    13561 cggacccgcc ggacccgccg acgaccaacg cacagcgccg gtcgtcggcg gtatcctgca
    13621 cctcgcaccg tcggcatgca ccgcaccgtc gacgggcacc gaaccaccgg cacacaccgg
    13681 tcgccggcac gcaccggcag gcgccgctcg tcggcacgca ccgtaggagg tcgtcgcggc
    13741 aaggcagacc ggtcagcagc ttgtcgcgac caaccgcagg gcgcgacacg actacaccat
    13801 cctgaagacg tacgaggcgg gcctcgtgct cgccggcacc gaggtcaagt cgctgcgcgc
    13861 gggacgggtg tcgcttgtcg acgccttcgc ccaggaacgc gacggcgagc tgctgctgca
    13921 cggcctgcac atcgccgagt acggctacgg cagctggacc aaccaccagc cccgccgtac
    13981 ccggaagttg ctgctgcgcc gggtggagat cgaccggatc ctggagcggc tacgcgacgg
    14041 cgggctgacc ctggtgcccc tgtcgatgta cttcgccaac ggctgggcaa aggtggagct
    14101 ggccctggcc cagggacggc gctcctacga caagcggcag gcgctggccg aacgggacgc
    14161 caaccgggag atcgcccgtg ccttcggcca gcatctcaag ggccgccgcc gctgactcac
    14221 ccccggccga ccacaccacc agataccact cacccccgcc ggcgcgatgc cacccggcgc
    14281 ccctggtgtg acgcctccgt ggccgcgcgg ggaattgccg tcacaaatgt tcggcaagaa
    14341 cagggaaatt gcgccttgaa tccgcgccga ggccaccgta accaggaaac tgcgcccccg
    14401 aatctcccag aggtgggcgc ggggtggggt gggcgtgggg tggcccccgg gatgggaatc
    14461 ccgggggccg tgcgtcgttc ggtcaggggg tggtttgggt gaattgtcgg atggtgactt
    14521 ggccgccgag ttggccggtg gtgtggtggt
//
