LOCUS       NZ_BMMJ01000011        22185 bp    DNA     linear   CON 09-SEP-2024
DEFINITION  Micromonospora yangpuensis strain CGMCC 4.5736 sequence11, whole
            genome shotgun sequence.
ACCESSION   NZ_BMMJ01000011
VERSION     NZ_BMMJ01000011.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Micromonospora yangpuensis
  ORGANISM  Micromonospora yangpuensis
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 232757)
  AUTHORS   Sun,Q. and Zhou,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 133X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014645775.1-RS_2024_09_09
            Annotation Date                   :: 09/09/2024 04:34:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,914
            CDSs (total)                      :: 5,857
            Genes (coding)                    :: 5,698
            CDSs (with protein)               :: 5,698
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 20 of 159
            Pseudo Genes (incomplete)         :: 144 of 159
            Pseudo Genes (internal stop)      :: 5 of 159
            Pseudo Genes (multiple problems)  :: 9 of 159
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:15:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 38251
            Orig. end                         :: 60436
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMMJ01000011.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22185
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22185
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22185
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12185]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12185
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            811..1569
                     /locus_tag="IEY64_RS21295"
                     /old_locus_tag="GCM10012279_43210"
     CDS             811..1569
                     /NRPS_PKS="Domain: ECH (13-213). E-value: 6.4e-54. Score:
                     174.8. Matches aSDomain:
                     nrpspksdomains_IEY64_RS21295_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007454342.1"
                     /locus_tag="IEY64_RS21295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_43210"
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="WP_091433069.1"
                     /transl_table=11
                     /translation="MSGGLRVTEHPDRLVVTLDRPEKRNAIDADLIAALHEVCAELEAR
                     PRLLLLTGGTEGIFAGGADIGQLRDRGRLDALAAINSAAFARVRALPMPTVAAVDGPAL
                     GGGAELAYSCDLRVCTDRAVFGQPEVRLGILAGAGATHRLPALIGEARAKELLFTGRRV
                     DAAEALRIGLVNRVVVEPGELLDVAHGLLDEIAKGSPLALRLTKLAVDAPPAAHPHLDL
                     VSQAVLFSDEEKHRRMTEFLERGRTRRPAD"
     aSDomain        850..1449
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEY64_RS21295_ECH.1"
                     /evalue="6.40E-54"
                     /label="IEY64_RS21295_ECH.1"
                     /locus_tag="IEY64_RS21295"
                     /protein_end="213"
                     /protein_start="13"
                     /score="174.8"
                     /tool="antismash"
                     /translation="LVVTLDRPEKRNAIDADLIAALHEVCAELEARPRLLLLTGGTEGI
                     FAGGADIGQLRDRGRLDALAAINSAAFARVRALPMPTVAAVDGPALGGGAELAYSCDLR
                     VCTDRAVFGQPEVRLGILAGAGATHRLPALIGEARAKELLFTGRRVDAAEALRIGLVNR
                     VVVEPGELLDVAHGLLDEIAKGSPLALRLTKLAVDAP"
     gene            complement(1623..2969)
                     /locus_tag="IEY64_RS21300"
                     /old_locus_tag="GCM10012279_43220"
     CDS             complement(1623..2969)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1282:
                     extracellular ligand-binding receptor"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012180420.1"
                     /locus_tag="IEY64_RS21300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_43220"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_091433072.1"
                     /transl_table=11
                     /translation="MLGTRVPRAAALAVTAALLLATSACGTDEPEEADTRPVRLYGSDG
                     NMQNSFAAELKDRADLVDGMKGTTPLTRLPESFTNRLRAVDPKLTDFLYAAESYDAVVI
                     SALAAQLAGSTEPAAIAKQIVGVTNGGQRCEDVAKCLELARDGQDIEYRGVSLNRAGFT
                     DTGEPATASYATLHFDDQKIDDGKTEFVGAGDESNASTKAPPRARKQTPAVLRDSGAPL
                     VLGGLLPRTGDLALAYPPLAAGSALALREINQAGGVLGEPMVWIDGDDGTNPTVAKATV
                     ASHVAAGVHVIIGAGASGISREVLPDVVAAGRILFSPSNTDASLSKVDDQGLYFRTAPP
                     DSLQGRALADVILRDGPRRIVLLARKDSYGEGLQGYVQAELERAGIGDDRVKLITYQPP
                     DSPEAPPVDFGSAAQEIRDYQAEAVLIIGFGESAPLIRALDDAGVRLHR"
     gene            3136..3525
                     /locus_tag="IEY64_RS21305"
                     /old_locus_tag="GCM10012279_43230"
     CDS             3136..3525
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020522542.1"
                     /locus_tag="IEY64_RS21305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_43230"
                     /product="hypothetical protein"
                     /protein_id="WP_091433075.1"
                     /transl_table=11
                     /translation="MTDLSQQLVDDATAILDSALDGDGVGVAQAFDTVVDRSGLAGAYE
                     VAWCLAATMVGDGPRGSGAALDFPGIDQAGYDTRWVARFVSAYANHDQDAGEALFGAAV
                     ADGQLPDCLATLAGSTVATLRSRAQ"
     gene            complement(3519..3980)
                     /locus_tag="IEY64_RS21310"
                     /old_locus_tag="GCM10012279_43240"
     CDS             complement(3519..3980)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY64_RS21310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10012279_43240"
                     /product="hypothetical protein"
                     /protein_id="WP_091433078.1"
                     /transl_table=11
                     /translation="MHHPSIADGRIEQLEVGMSVKIARVLATTVAVSVAALGTPAEAAP
                     QNQFGTTASCYGGSVRSYFERAGSGGDAGPYRTSTRCRDINVRNASPFAVDACVIFIDQ
                     TGKCNYWTYLPAKSGWVVVATNVRDGVNFKVRFVTQRYEYEPLTAHHAY"
     misc_feature    complement(3971..3986)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.73"
                     /tool="antismash"
     gene            4055..4762
                     /locus_tag="IEY64_RS21315"
                     /old_locus_tag="GCM10012279_43250"
     CDS             4055..4762
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007074004.1"
                     /locus_tag="IEY64_RS21315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_43250"
                     /product="DUF2786 domain-containing protein"
                     /protein_id="WP_091433080.1"
                     /transl_table=11
                     /translation="MPEAMLSKIRKLLAKAEDPACTAAESAAFTAKATELIARYGVDQA
                     LLAARDPGVDPVGDRVVDVPAPYARDKAGLLAAVADPLRCRCVRRRDGAGYQLHLFGFA
                     SDLARVDLLFTSLLVQAAHGLAGAIVPAGEQPAAFRRSWLAGFAQVIGERLRQAEAGAA
                     TRIDGPSYALVLADRSDRVQRRVAEVYPRLRTAPPRRLVGRGFGSGVEAGHRADLGGTA
                     IPTPSPPNPALPA"
     gene            complement(4789..5283)
                     /locus_tag="IEY64_RS21320"
                     /old_locus_tag="GCM10012279_43260"
     CDS             complement(4789..5283)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (15-158). E-value:
                     8e-09. Score: 28.0. Matches aSDomain:
                     nrpspksdomains_IEY64_RS21320_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018811918.1"
                     /locus_tag="IEY64_RS21320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_43260"
                     /product="SRPBCC family protein"
                     /protein_id="WP_091433083.1"
                     /transl_table=11
                     /translation="MGQGSTNVRQESARFSLRSSLVVPVPPEEAFAGFTGGLAGWWVRE
                     YTWSGPVALVELGVEPRAGGMLYEIGPHGFRADWGRVLTWDPPHRLVFTWQIGPDRAPL
                     PDPATASEVEVWFQPDGPGQTRVTVEHRHFDRHGAAAEGYREALTAGWHELLTRYRASL
                     A"
     aSDomain        complement(4810..5238)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEY64_RS21320_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="8.00E-09"
                     /label="IEY64_RS21320_Polyketide_cyc2.1"
                     /locus_tag="IEY64_RS21320"
                     /protein_end="158"
                     /protein_start="15"
                     /score="28.0"
                     /tool="antismash"
                     /translation="SLRSSLVVPVPPEEAFAGFTGGLAGWWVREYTWSGPVALVELGVE
                     PRAGGMLYEIGPHGFRADWGRVLTWDPPHRLVFTWQIGPDRAPLPDPATASEVEVWFQP
                     DGPGQTRVTVEHRHFDRHGAAAEGYREALTAGWHELLTR"
     misc_feature    complement(5258..5271)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.67"
                     /tool="antismash"
     misc_feature    5531..5546
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.23"
                     /tool="antismash"
     tRNA            complement(5593..5666)
                     /anticodon=(pos:complement(43881..43883),aa:Phe,seq:gaa)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="IEY64_RS21325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="GCM10012279_t00430"
                     /product="tRNA-Phe"
     gene            complement(5593..5666)
                     /locus_tag="IEY64_RS21325"
                     /old_locus_tag="GCM10012279_t00430"
     tRNA            complement(5749..5822)
                     /anticodon=(pos:complement(44037..44039),aa:Asp,seq:gtc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="IEY64_RS21330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="GCM10012279_t00440"
                     /product="tRNA-Asp"
     gene            complement(5749..5822)
                     /locus_tag="IEY64_RS21330"
                     /old_locus_tag="GCM10012279_t00440"
     tRNA            complement(5854..5926)
                     /anticodon=(pos:complement(44141..44143),aa:Glu,seq:ttc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="IEY64_RS21335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="GCM10012279_t00450"
                     /product="tRNA-Glu"
     gene            complement(5854..5926)
                     /locus_tag="IEY64_RS21335"
                     /old_locus_tag="GCM10012279_t00450"
     gene            complement(6070..6888)
                     /locus_tag="IEY64_RS21340"
                     /old_locus_tag="GCM10012279_43270"
     CDS             complement(6070..6888)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473455.1"
                     /locus_tag="IEY64_RS21340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_43270"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_091433087.1"
                     /transl_table=11
                     /translation="MNARIPLAVGLGLLLLVTGCGEPDSRTEPGAAPAWSSAPSPTPEA
                     TTGPVPTPAATPSPTRTSPPPPPPVRPRPTALPAGLRKTTGVRGVALTFDDGPDPVYTP
                     RILDQLREAKVKATFCVVGTRARRHPELVARIAREGHQLCNHSWQHDMDLGRRPLAAIR
                     ADLKRTNKAIRAAVPDAKIPFYRQPGGRWTAEVVAVAKQLDMRSLHWTVDPQDWAKPTA
                     ATLTKRVHKAVRPGAVVLLHDGGGDRTATVTACPRLITEIKDRYGITKAR"
     gene            complement(7012..7950)
                     /locus_tag="IEY64_RS21345"
                     /old_locus_tag="GCM10012279_43280"
     CDS             complement(7012..7950)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007454358.1"
                     /locus_tag="IEY64_RS21345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_43280"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_091433090.1"
                     /transl_table=11
                     /translation="MADEALSAGAVARRLGVAVTTLRTWHQRYGLGPSHHVPGHHRRYT
                     PDDLARLEIMRRLTTEGVSPAEAARWARQAPEPGQHVNGGQPRLRRDGGGTAIPVGRAG
                     PAARGLARAAMRLDPVAISLAITQSLAANGVIATWEGLLRPVLAGIGERHAATAGLIDV
                     EHLVSRCVSESFATVVRAGTVTGPARILLSCADEEQHTLPLEALAAALSEAGVAYRMLG
                     ARVPPAALVEAVNRTGPAGVVVWSHTRATADPRQLTALLAVPRRPLLVLAAGPGWRADT
                     LPAGVVRPIDLAEAVSLASAVRDSLEQSTAD"
     gene            complement(7940..8494)
                     /gene="idi"
                     /locus_tag="IEY64_RS21350"
                     /old_locus_tag="GCM10012279_43290"
     CDS             complement(7940..8494)
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="idi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018587072.1"
                     /locus_tag="IEY64_RS21350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_43290"
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_091433093.1"
                     /transl_table=11
                     /translation="MTSREGHLVELVDDAGQAIGEETVSTAHEPPGRLHRAFSVLLTDP
                     AGQVLLQRRAEVKTRFPLRWANSCCGHPLPGESLVEAANRRLGEELGVEPVELTEIGVY
                     VYYAEDPLTGRVEFEYDHVLRGSLPAGVTPRPDPAEVAELRWADPATVAADLDVDPRSY
                     APWLGGVLDRLLRPTEPSGGR"
     gene            complement(8491..9972)
                     /gene="crtI"
                     /locus_tag="IEY64_RS21355"
                     /old_locus_tag="GCM10012279_43300"
     CDS             complement(8491..9972)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018217624.1"
                     /locus_tag="IEY64_RS21355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_43300"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_091445749.1"
                     /sec_met_domain="DAO (E-value: 3.9e-19, bitscore: 63.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTVNGRTDRVVVVGAGLGGLACALHLAGSGRQVTVVEREPVPGG
                     RAGRLSVDGYEFDTGPTVLTMPDLIAEALDAVGEQLSDWVELMPLDPAYRAYYPDGSTL
                     DVITDTTRMAAEISRVCGPREADGYLRFVDYARRLWQLERADFIERNLDAPTDLLTGNL
                     LKLLASGAFRRLQTKINQFFRDPRTQRIFSFQAMYAGLAPHDALAIYTVIAYLDSVAGV
                     YFPRGGIHAVSRGMAGAAEKHGVQFRYDTTVTRVETAHGRATGVTTADGEFIPADVVVL
                     NPDLPVAYRDLLPPTRTRRLTYSPSCVVLHVGSRQGYRKIAHHNIHFGRPWKGTFDEVI
                     RRGELMSDPSLLVTNPSRTDPSVAPAGGHTYYVLAPVPNLEKAPFDWPGDLTRRYSDQL
                     IDTLEQRGYVGFGDGVEVLRAITPAQWAEQGMAAGTPFAAAHSLFQTGPFRPSNLHRTL
                     SNVVFVGSGTQPGVGVPMVLISGKLAAARVTGGAS"
     gene            complement(10001..11155)
                     /locus_tag="IEY64_RS21360"
                     /old_locus_tag="GCM10012279_43310"
     CDS             complement(10001..11155)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019901498.1"
                     /locus_tag="IEY64_RS21360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_43310"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_091433097.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.7e-48, bitscore:
                     158.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANDAVAENDLRLTADRPTEGDDPVGAVLAAYTRDLVEAVDHTLA
                     AFLSDEVESLRAIDAAMGGFAATARECVLSGGKRVRPTFAYWGWRGVAGGDTPLPAVLP
                     ALAALELLHTFALVHDDVMDASATRRGRPTAHRALAAQHVAAGRRGDPDRFGDSVAVLV
                     GDLCLVWADRLLARAAVGADRLLDVRRCYDQMRVETIAGQYLDVLGESDAANWSVDRAL
                     RVARYKTASYTVQRPMLFGACLAGVGPDEPLGVAYTRYGLAVGEAFQLRDDLLGVYGDP
                     ARTGKPAGDDLRTGKPTALLMLARQAADPAQRRALDRAGGATDEREIADLAEVVATTGA
                     VDRIEQMIADRVSEALAALDLAPIDETARTALVGLATAATRRQA"
     misc_feature    11121..11135
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.52"
                     /tool="antismash"
     gene            11223..12185
                     /locus_tag="IEY64_RS21365"
                     /old_locus_tag="GCM10012279_43320"
     CDS             11223..12185
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018255060.1"
                     /locus_tag="IEY64_RS21365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_43320"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_091433102.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.3e-114,
                     bitscore: 375.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 3.4e-65,
                     bitscore: 214.0, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDIDLTAAYDRCRELHRRHGRTYYLATRLLPAWKRRHVHALYGFT
                     RYADEIVDRTEDLPPAERAARLDDWAGRFLAGLHGEPVDDPLLPAVLHTIAVFDLDRDD
                     FASFLKSMAMDLTVTSYRTYDALLDYMEGSAAVIGTMMLPILGSSDPAAAREPARQLGF
                     AFQLTNFIRDVGEDLDRGRTYLPDEDLAAFGVTRDDLLAARDRGAGTEAIRELIRYEVR
                     RAQAHYVAAADGITLLDPASQACMRTAYALYGGILDEVAGQDHDVFVRRATVPQRRRMS
                     VAARSLLTPTGTPVVVPGPDLAGPLAEADAVPAPRPVGG"
     gene            12191..13507
                     /locus_tag="IEY64_RS21370"
                     /old_locus_tag="GCM10012279_43330"
     CDS             12191..13507
                     /EC_number="4.1.99.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003904 - deoxyribodipyrimidine
                     photo-lyase activity [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014440269.1"
                     /locus_tag="IEY64_RS21370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_43330"
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="WP_091433106.1"
                     /transl_table=11
                     /translation="MRTAIVLFTRDLRVHDHPALATSCAAFDRVVPTFVLDPALADRSP
                     NRTRFLRQSLADLRENLRGLGGDLVLRQGDPVTETIRLAGEVGAEAIAVSADVSRYARR
                     RERRLRAECERHRLHLRLFPGLTVVDPGALRPGGGEHYKVFSPYFRAWQGAQWRTALAR
                     PERIELPTGVPVGRLPALPAGASPDAAAGGETVARRRLRDWLPNLGGYGDQHDDLAADD
                     TSRLSPYLRFGCLSPLEVVERVADRADPFVRQVCWRDFYYQAAAAFPDLDRTAFRAGVT
                     EDWRYDTDALDAWTEGRTGVPIVDAGMRQLHAEGWMHNRARLITAGHLTKQLRLDWRAG
                     LAVFGHWLLDGDVPNNSGNWQWVAGTGHDTRPYRGFNPIRQAHRYDPDGAYVRRWLPEL
                     AAIEGGAVHEPWRLPDAVRRTLDYPPPLPPPGPPPPWLR"
     gene            13643..14155
                     /locus_tag="IEY64_RS21375"
                     /old_locus_tag="GCM10012279_43340"
     CDS             13643..14155
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY64_RS21375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10012279_43340"
                     /product="hypothetical protein"
                     /protein_id="WP_139135551.1"
                     /transl_table=11
                     /translation="MTAWLDDSTKADFDTFIAGLEPDFASQPLTRAYVKELQKLGKQYR
                     LLRDAAERNPASVDQQSLVRAYQPIAQKKEELNEYVRDFIYTPESSPEPAPVNPQASTG
                     MPAPPQPQAGAEQRARPAIPVFNPASQDWAAATGPGWPGGTSGAAQSSTPAGRAPDQPR
                     SRGGRNR"
     gene            14186..14743
                     /locus_tag="IEY64_RS21380"
                     /old_locus_tag="GCM10012279_43350"
     CDS             14186..14743
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007463676.1"
                     /locus_tag="IEY64_RS21380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_43350"
                     /product="Uma2 family endonuclease"
                     /protein_id="WP_091433110.1"
                     /transl_table=11
                     /translation="MSAETVGRYMPAVVTLGDLAAMNAADPNGHRYETSPEGVLSVMPP
                     PDSEHAMIASRVFAWLIMAGWPAEQVLQAAGIRITGPAGDGGRIPDLTVWRKPPPRGVW
                     SATDGLLAVVEIVSPGSEAMYSVTKVREYASAGIGQYWVVERDSRQTVTLHRLVGDAYQ
                     EQARMPLSWLLQTAPGEHLDTP"
     misc_feature    14225..14238
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.5"
                     /tool="antismash"
     gene            14832..16397
                     /locus_tag="IEY64_RS21385"
                     /old_locus_tag="GCM10012279_43360"
     CDS             14832..16397
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283455.1"
                     /locus_tag="IEY64_RS21385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_43360"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_091433112.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.6e-44, bitscore:
                     145.4, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEPELVDVVVVGLGVGGDEVAGKLAEAGLSVVGIERDLVGGECP
                     YWGCVPSKMMIRAANALAEARRVDGLAGTAQVRPDWSPVAKRIREEATDTWDDRVAVDR
                     FVGRGGTFVRGSGRLDGPGRVRVGDRVFQARYGVVLGTGTRPSIPPLPGLADTPYWTNH
                     QAIEVEELPASLLSLGGGAIGLELAQVFARFGVQVTVLERSERVLAVEEPESSEVAAAA
                     LRADGVTIETGVGAERVSHDGQHFTVHAAGGAEFTAERLLVVTGRRAHLAELGLDTVGM
                     DPDQRYLPVDDRMRAGDGIWAVGDLTGEGAFTHIAMYQAAIVVADLLDHARRATAGPDP
                     SGTASVVGGAVGAASGVPAAGGPASAGSGTAGSGTAASGAVGSGVAGSGAVGAGVGGPQ
                     GVARADYRALPRVTFTDPEIGAVGLTERQARERGLNVQVGFAELASSTRGWIHRGDGFI
                     KLVADADRGVLVGATSAGPAGGEVLAGLVVAVHAAVPISQLRHMIYAYPTFHRAIETAL
                     HDLR"
     gene            16480..17331
                     /locus_tag="IEY64_RS21390"
                     /old_locus_tag="GCM10012279_43370"
     CDS             16480..17331
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785440.1"
                     /locus_tag="IEY64_RS21390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_43370"
                     /product="DUF2231 domain-containing protein"
                     /protein_id="WP_091445751.1"
                     /transl_table=11
                     /translation="MRAFLTKIEQARALDRVGDRVQRVVESTLRPQRVRDLLHGVWLGH
                     PLHPAMVQVPVGAWISAAVVDLLPGQRRAATALVGLGTVSAVPAAVAGFNDWAALSRDQ
                     RRVGLVHAAANVVGLALYSGSLAARLTGRHGTGRALSYLGLGAVSAGAYLGGHLAYTQG
                     AQVNQSVSELHRISEGWHPLGELAALPDRELLTREVDDVSVILYRHGDEVTVMLERCPH
                     QSGPLGEGEVQQIDGHACVVCPWHGSAFRLNGGEVVHGPSGNDQQTLPTRVVEGVLETR
                     LP"
     gene            complement(17592..18728)
                     /locus_tag="IEY64_RS21395"
                     /old_locus_tag="GCM10012279_43380"
     CDS             complement(17592..18728)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473464.1"
                     /locus_tag="IEY64_RS21395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_43380"
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="WP_091433116.1"
                     /transl_table=11
                     /translation="MTAPRGTAVRRTGQVLTGLGALTVLGAVLVGGPLALVALAGNPLP
                     DHLPTLAEVGSTLTSRDDGQLFLRALALVGWFGWATFAFSVLVELVAQTFRRPAPKLPG
                     MRRQQKAAAALVGSIALIIAASPAATAATTLAGPYPAASSPASVTQVGPERAGYPDSGV
                     GGSVRLAGLDRTAQLAGADRTAEVDAPVYRVARGDYLGTVAERYLDDFGDYREVAKLNR
                     LRDPDRIRPGQLLKLPTTADDQGSRAHASGRLVARPAEAAPPGHDAPAQPPTAPGGPAS
                     TAPGAEASPPSAEQPAPVVPPSTDHTSGSPVMAVGASRASDGDGVNRPLAVSAVLAVAS
                     IVGAQIGAVLGLRRRPAAPRPPAPHPGLTNPSGRHRRD"
     gene            complement(18740..19192)
                     /locus_tag="IEY64_RS21400"
                     /old_locus_tag="GCM10012279_43390"
     CDS             complement(18740..19192)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012015642.1"
                     /locus_tag="IEY64_RS21400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_43390"
                     /product="pilus assembly protein TadG-related protein"
                     /protein_id="WP_091433119.1"
                     /transl_table=11
                     /translation="MNRRRWSVGAAEPTGDAGRVSLFLAVAMAGVLVVIGLAFDGSGQL
                     RSMQRAENLAAEAARTGGQSIDRARAIAGGSKEIDEDDARAAVRSYLAAAGVASHSVSF
                     PVIEGEKHIRVRVDVAYDRLLLGLFGFGDSVTVSGEATARTLTEGP"
     gene            complement(19189..19656)
                     /locus_tag="IEY64_RS21405"
                     /old_locus_tag="GCM10012279_43400"
     CDS             complement(19189..19656)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018735072.1"
                     /locus_tag="IEY64_RS21405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_43400"
                     /product="TadE/TadG family type IV pilus assembly protein"
                     /protein_id="WP_091433122.1"
                     /transl_table=11
                     /translation="MSGRSDRGSVSVEVTILAPAFLSLIVLAGVAGRTAIAAEAIDSAA
                     HHAARAASISRDADSAEAAARRAAREQLDWSGLSCTGAPAVTFTGSVEGRPATFDDAFD
                     SAVGESSAVTVRVTCTVSFTDLNLPAIPGMPTRRTVTAAFTSPLDRYRSRP"
     gene            complement(19653..20180)
                     /locus_tag="IEY64_RS21410"
                     /old_locus_tag="GCM10012279_43410"
     CDS             complement(19653..20180)
                     /GO_process="GO:0009297 - pilus assembly [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473467.1"
                     /locus_tag="IEY64_RS21410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_43410"
                     /product="TadE family protein"
                     /protein_id="WP_091433125.1"
                     /transl_table=11
                     /translation="MPRTPPTAHDRAAPAARCHRTPVATPVPGPPGGPTRVRPASVTAA
                     VASGADRGASPVELAVVMPLILLLLFASIQAAAWFVARATALNAAQSGVNAQRVHQAPA
                     GAGEARATGFLTAAGDWLVGWERAGPRCVTTETEVTCTVTGRSLSLVPGVSFPVRQTAH
                     GTVERWTTGDPQ"
     gene            complement(20186..20386)
                     /locus_tag="IEY64_RS21415"
                     /old_locus_tag="GCM10012279_43420"
     CDS             complement(20186..20386)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730906.1"
                     /locus_tag="IEY64_RS21415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_43420"
                     /product="hypothetical protein"
                     /protein_id="WP_091433128.1"
                     /transl_table=11
                     /translation="MRLVAYLHIVFLDRLAELRRAGDRGDSPVPTAVIIFGLVAAAIAV
                     TALVSTKAKSWMDAIPGPAAP"
     misc_feature    complement(20353..20367)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.38"
                     /tool="antismash"
     gene            complement(20414..21277)
                     /locus_tag="IEY64_RS21420"
                     /old_locus_tag="GCM10012279_43430"
     CDS             complement(20414..21277)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012184936.1"
                     /locus_tag="IEY64_RS21420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_43430"
                     /product="type II secretion system F family protein"
                     /protein_id="WP_091445753.1"
                     /transl_table=11
                     /translation="MLSWQLTLAVVGGGLVGLGLFLVVQEALPATPALGPALRRLHQPP
                     GATRPGTGRHLDWLGGLARWVRPPHRELALIDRTPEQYTLSLLLSTLIGLAAPTLLSGV
                     LFLAGTELPVVVPVLGSVGAAAVCALIAHRDVLVRAEAARAEFRQAVSAYLDLVALQLS
                     AAHGPVQSLERAAMVCDGWVFDRLRESLRIAQMQMHSPWDELRDLAEKLGIPELGDVGA
                     IMRSSGSEGAQVHETLRSRADSLRDQIRTDNLARAEGITSRLDIPGALLVFVLLGFAVY
                     PFVARL"
     gene            complement(21277..22173)
                     /locus_tag="IEY64_RS21425"
                     /old_locus_tag="GCM10012279_43440"
     CDS             complement(21277..22173)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018808838.1"
                     /locus_tag="IEY64_RS21425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_43440"
                     /product="type II secretion system F family protein"
                     /protein_id="WP_091433131.1"
                     /transl_table=11
                     /translation="MNVELVAVVSGAACVAGMVLAVVAVVGTRRPRRTRPGAGNDLRRF
                     LLGTDTSRRQQRRRRSLLVGAVVAGALAFLLTGLPVVGLLVALAVPGVPWLFAVGREEQ
                     RAIARIEAVGEWTRRLKDVSAVGQGLQQAIASTVTTVPEEIEEEVRVLAARLQAGWSAR
                     AALLAFADEIGDPVCDQVVAALILHLTDRGERLGDVLGSIAGAAAAEVATRREIEAKRT
                     QPRFAVRFLTGMTLATLAYGLLNTEYMRPYGTPTGQLVMVVLGTCFVGLLVWVRAMSQP
                     PQPARFLPAPDPEEALR"
ORIGIN
        1 cggctacctg gtcgaactgg tcgaggtgga ccccgaccgg gcccaggcgg ccgggaagcg
       61 actggccgac ctctgggacc gggcggtggg gcgcggccgg ctgaccgccg aggaggccgc
      121 cgcgaaccgg cgacggctca ccctggtcgg cgggttggcc gaggtagccg ccgaaccggc
      181 cgtggtcgtc gaggccgtac cggagcggtt ggagctcaaa cgggccgtac tgcgccaggc
      241 cgccacgctg cgcccggcgc tgctgggcag caacacctcc agcatcccga tcgccgagct
      301 ggcggccggg ctggaccgcc cggagcgctt cctcgggctg cacttcttca acccggtctg
      361 ggcgatggcg ctgctggagg tcgtggtcgg cccggccacc gccgagcaga ccaccgcggc
      421 gggtgtcgcg ctcgcccgtc ggctcggcaa ggaccccgtc gtggtacgcg acctgcccgg
      481 cttcgccacc tcacggctgg gcgtgacgct cggcctggag gcgatccgta tgctcgccga
      541 cggggtggcc agcgcggccg acatcgacaa ggcgatggtg ctgggctacc ggcatcccgt
      601 cggtccgctg gagctcaccg acctggtcgg actggacgtc cggctggaca tcgcccacac
      661 gctccaggcc gcgtacggcg accggttcgc cccgccgccg ctgctggagg agttggtggc
      721 cgcgggccgg ctgggcaaga agtcggggca cggcttctac cgctgggtcg acgggtcgaa
      781 ggtggactcc ccggacgggg agccgacccg atgagcggtg gactgcgggt caccgaacac
      841 ccggaccggt tggtggtgac gctggaccgg ccggagaagc gcaacgccat cgacgccgac
      901 ctgatcgccg cgctgcacga ggtctgcgcc gagttggagg cccgcccgcg gctgctgctg
      961 ctcaccgggg gtaccgaggg catcttcgcc ggcggggcgg acatcggcca gctgcgggac
     1021 cggggtcggc tggacgcgct cgcggcgatc aactccgcgg ccttcgcccg ggtccgggcc
     1081 ctgcccatgc cgaccgtggc ggccgtggac gggccggcgc tgggcggcgg cgccgaactg
     1141 gcgtactcgt gtgatcttcg agtgtgcacg gaccgggcgg tcttcggtca gccggaggtc
     1201 cgactgggga tcctggccgg tgccggcgcg acccaccggt tgccggcgtt gatcggcgag
     1261 gcccgggcca aggaactgct cttcaccggc cggcgggtgg acgccgccga ggcgctgcgg
     1321 atcggcctgg tcaaccgggt ggtggtcgag cccggcgagc tgctggacgt cgcccacggg
     1381 ctgctcgacg agatagccaa gggatcgccc ctggcgctgc ggctgaccaa gctggcggtg
     1441 gacgccccac cggccgccca tccgcacctg gacctggtca gtcaggcggt ccttttctcc
     1501 gacgaggaga agcaccgccg gatgaccgag ttcctggagc ggggccgcac ccgccgcccg
     1561 gcggactgac cccggcggtt cagcgacggc gcgccgcacc cggtggggtg cggcgcggcg
     1621 ggtcagcggt gcagccgcac cccggcgtcg tcgagggccc ggatcagcgg ggccgactca
     1681 ccgaagccga tgatcagcac ggcctccgcc tggtagtccc tgatctcctg ggcggcggag
     1741 ccgaagtcga caggcggggc ctcggggctg tccggcggct gataggtgat cagcttgacc
     1801 cggtcgtcac cgatgccggc ccgctccagc tcggcctgga cgtacccctg caggccctcg
     1861 ccgtaggagt ccttgcgggc cagcagcacg atccggcgcg ggccgtcgcg caggatcacg
     1921 tcggccagcg cccgaccctg gaggctgtcc ggtggggcgg tacggaagta gagcccctga
     1981 tcgtccacct tgctcaggct ggcgtcggtg ttggaggggg agaagaggat ccggccggcg
     2041 gcgaccacgt ccggcagcac ctcccgggag atccccgagg cgccggcgcc gatgatgacg
     2101 tgcacccccg cggcgacgtg cgacgccacg gtggccttgg ccacggtcgg gttggtgccg
     2161 tcgtcgccgt cgatccacac catcggctcg ccgagcaccc cgccggcctg gttgatctcc
     2221 ctgagcgcca gcgcggaacc cgcggccagc ggcgggtacg ccagagccag gtcaccggta
     2281 cgcggcagca ggccgcccag gaccagcggg gcaccggagt cccggagcac cgccggagtc
     2341 tgcttgcgcg cccgcggcgg tgccttggtg ctcgcgttcg actcgtcacc ggcaccgacg
     2401 aactcggtct tgccgtcgtc gatcttctgg tcgtcgaagt gcagcgtggc gtagctggcg
     2461 gtggccggct caccggtgtc ggtgaaaccg gcccggttca gcgacacgcc ccggtactcg
     2521 atgtcctgac cgtcgcgggc caactccagg cacttcgcga cgtcctcgca gcgttgcccg
     2581 ccgttggtga cgccgacgat ctgcttggcg atcgcggccg gttcggtgct gccggcgagc
     2641 tgggcggcca acgcgctgat caccacggcg tcgtacgact ccgcggcgta caggaagtcg
     2701 gtgagcttcg ggtcgaccgc gcggagccgg ttggtgaagc tctccggcag ccgggtcagc
     2761 ggggtcgtgc ccttcatgcc gtcgaccagg tcggcccggt ccttcaactc cgcggcgaag
     2821 gagttctgca tgttgccgtc gctcccgtag aggcgcaccg gtcgggtgtc cgcctcttcg
     2881 ggctcgtccg tcccgcacgc gctggtggcg agcaggagcg ccgcggtcac cgccagtgcg
     2941 gcggcgcgcg ggactcgggt accgagcatg gtcgtccttc ctgcgggaaa ggtccgctgc
     3001 gcaccttagc gtgctgtcgg agcaggtggg tgtcaggagc cggatcaatt gaccgccacg
     3061 caccgccggg caccgaacgt caccgggtca ctgtgcagcg tgagcgactt gacctatcct
     3121 cctactgtgc ggcgagtgac ggacctatca cagcagctgg tcgacgatgc caccgccatt
     3181 ctcgactcgg cgctggacgg cgacggggtc ggggtggcgc aggcgttcga cacggtcgtc
     3241 gaccgatccg ggctggccgg tgcctacgag gtggcctggt gcctggccgc cacgatggtc
     3301 ggggacggcc cgcgcggctc gggtgccgcg ctcgacttcc ccggcatcga ccaggccggg
     3361 tacgacaccc gctgggtcgc ccggttcgtc agtgcgtacg ccaaccacga ccaggacgcc
     3421 ggcgaggccc tgttcggcgc ggcggtggcc gacggtcagc tgccggactg cctggccacc
     3481 ctggccgggt cgacggtggc cacgctgcgc agccgcgctc agtaggcgtg gtgggcggtc
     3541 agcggctcgt actcgtagcg ttgggtcacg aaacggacct tgaagttgac cccgtcgcgc
     3601 acgttggtgg ccaccaccac ccagccggac ttggcgggca ggtaggtcca gtagttgcac
     3661 ttgccggtct ggtcgatgaa gatcacgcag gcgtcgaccg cgaacgggct ggcgttgcgg
     3721 acgttgatgt cccggcaacg ggtgctggtc cggtacggcc cggcgtcgcc tcccgagccg
     3781 gcgcgttcga agtacgaccg gactgagccg ccgtagcagc tggccgtggt gccgaactgg
     3841 ttctgcggcg cggcttcggc cggggtgccg agggcggcca ccgacaccgc gaccgtcgtg
     3901 gccagcaccc gggcgatctt gactgacata cccacctcca actgctcgat ccgaccgtcc
     3961 gcaatggacg gatgatgcat cgcgatgatg gtacgcgtcg atggatgccc tgtcgccccc
     4021 agccgtcccc ggccggtgtg gtagctctgt tcacatgccg gaggccatgc tcagcaagat
     4081 ccgcaagctg ttggccaagg ccgaggaccc ggcctgcacc gccgccgagt ccgccgcgtt
     4141 caccgccaag gccaccgaac tgatcgcccg gtacggcgtc gatcaggccc tgctcgctgc
     4201 ccgtgacccg ggcgtcgacc cggtcggtga ccgggtggtg gacgtcccgg ccccgtacgc
     4261 ccgggacaag gccggcctgt tggccgcggt cgccgatccg ctgcgctgcc gctgcgtacg
     4321 tcgccgggac ggcgccgggt accagctgca cctgttcggc ttcgccagcg acctggcgcg
     4381 ggtcgatctg ctcttcacct cgctgctggt gcaggccgca cacggcctgg ccggggcgat
     4441 cgtgccggca ggcgaacagc cggccgcgtt ccgccggtcc tggctggccg gcttcgccca
     4501 ggtgatcggt gagcggctac gccaggccga agcgggggcg gccacccgca tcgacggccc
     4561 ctcgtacgcc ctggtgcttg ccgaccggtc ggaccgggtg cagcggcggg tcgccgaggt
     4621 ctatccccgg ctccggaccg cgccaccccg acggctggtc ggccgggggt tcggctccgg
     4681 agtcgaggcc ggtcaccggg ccgacctggg cggcaccgcc atccccaccc cgtcgccacc
     4741 gaaccccgct ctgcccgcct gagccgccct ggtgggcgcg gggcggggtc aggcgagcga
     4801 ggcgcggtaa cgggtgagca gctcgtgcca gccggcggtg agggcctccc ggtagccctc
     4861 ggccgccgcg ccgtgcctgt cgaagtgccg gtgctccacc gtcacccggg tctgccccgg
     4921 gccgtccggc tggaaccaca cctccacctc gctggccgtg gccggatcgg gcagcggtgc
     4981 ccggtccggc ccgatctgcc aggtgaagac cagccggtgt ggtggatccc aggtgagaac
     5041 tcgtccccag tcggcccgga aaccgtgcgg gccgatctcg tagagcatgc cgccggcccg
     5101 gggctcgacg cccagctcga ccagggccac cgggccggac caggtgtact cccggaccca
     5161 ccagccggcc aggccgccgg tgaagcccgc gaatgcctcc tccgggggga ccgggaccac
     5221 gagactgctg cgtagcgaga accgcgcgct ctcctgccgg acgtttgtgc tcccctgtcc
     5281 cataggcccg gaccataccc cctggtaaca ccccccgcag cccgccgaag tgtgtcgtcg
     5341 gcgcattggt ccagtgaggt ggtgctggcc ggggcgggcc gagaatcgcc ggctacctca
     5401 gcccttgagg aggcccaagg tcgcgccagc cactctgagg ccgatctgcg tccgggttgc
     5461 ccaacggctc atgtccgggc gggttcgaga agccggggcc gaccgcaccg gcgctgcgtg
     5521 tgtccgggaa aaggaaaatc ctcaccggcg tttccgcagg tgaggattcc tgtagcccgg
     5581 cgaaaggcta tgtggccagg ggcggggtcg aaccgccgac cttccgattt tcagtcggac
     5641 gctcgtacca actgagctac ctggccgtat cttcggctca tcgtacccgt agtggggcac
     5701 ctgggccgat acgcagaacg ccgcgcgaag agcgcggcgt cggcgctgcg gtcctgacgg
     5761 gacttgaacc cgcgacctcc gccttgacag ggcggcgagc actccaactg ctccacagga
     5821 cctcatgtgt tgcctccggc cggagccgga tcgtgccccc aacgggattc gaacccgtgc
     5881 taccgccttg aaagggcggc gtcctgggcc gctagacgat gagggcggcc ccgccatcat
     5941 tgcacactcg caacttcaag cggacttgct cccatccggc cccgccggag gcttcgaaag
     6001 catacgtgat gctcggccgc tcgaccaaac cggtagggcg ctgggcgctg tgtcccggga
     6061 agtgccaggt cagcgcgcct tcgtgatgcc gtaccggtct ttgatctcgg tgatcagccg
     6121 ggggcaggcg gtgacggtgg cggtgcggtc cccgcctccg tcgtgcagca ggacgaccgc
     6181 gccggggcgg accgccttgt ggacccgctt ggtgagggtg gcggcggtgg gcttggccca
     6241 gtcctgcggg tcgacggtcc agtgcagcga ccgcatgtcg agctgcttgg cgaccgccac
     6301 cacctcggcg gtccaccggc cgcccggctg gcggtagaac gggatcttcg cgtccggcac
     6361 ggccgccctg atcgccttgt tcgtccgctt caggtcggcc cggatggcgg ccagcgggcg
     6421 gcgtcccagg tccatgtcgt gctgccaact gtggttgcag agctggtggc cctcgcgggc
     6481 gatccgggcc accagctccg ggtggcggcg ggcccgggtg ccgaccacgc agaaggtggc
     6541 cttcaccttg gcctcgcgca gctggtccag gatccggggg gtgtagaccg ggtccggccc
     6601 gtcgtcgaag gtcagcgcga caccgcgtac cccggtggtc ttgcgcaggc cggcggggag
     6661 cgcggtggga cggggccgta ccggtggcgg tggtggcggt gaggtgcggg tcgggctcgg
     6721 ggtggcggcg ggtgtgggga cgggcccggt ggtggcttcg ggagtgggcg acggtgcgga
     6781 cgaccaggcg ggcgcggcac cgggttcggt tctgctgtcg ggctcgccgc agccggtgac
     6841 gagcagcagc aggccgaggc cgacggcgag agggatgcgg gcgttcaacg ttcgctcccg
     6901 gggatggcgg gggtggcgga cgctcagacg ctagtcgagg ccgccaacct ccggcaccgc
     6961 cggtcggtag gccctggcgg tgaccgttcc gggcgctgcc cgcaccgctg gtcagtccgc
     7021 cgtcgactgt tccagggagt cccgtacggc gctggcgagc gagaccgcct cggccaggtc
     7081 gatcgggcgg accaccccgg cgggcagcgt gtcggcccgc caacccggcc cggcggccag
     7141 caccagcaac ggtcggcggg gcaccgcgag cagggcggtg agctggcgcg ggtcggcggt
     7201 ggcccgggtg tgcgaccaga ccaccacgcc ggccgggccg gtgcggttga ccgcctccac
     7261 cagcgccgcc gggggcaccc gggcaccgag catccggtac gccaccccgg cctcgctgag
     7321 cgcggcggcc agcgcctcca gtggcagggt gtgctgttcc tcgtcggcgc aggagagcag
     7381 gatccgggcc ggcccggtga ccgtgccggc ccggacgacc gtggcgaagg actccgagac
     7441 gcagcgggag accaggtgtt ccacgtcgat caacccggcg gtggcggcgt gccgctcacc
     7501 gatgccggcc agtaccggtc gcagcagccc ctcccaggtg gcgatcaccc cgttggcggc
     7561 cagcgactgg gtgatcgcca gactgatcgc caccgggtcc agccgcatgg cggcgcgggc
     7621 caggccccgg gcggccggcc cggcccggcc gaccgggatc gcggtgccac caccgtcgcg
     7681 gcgcaggcgc ggctggccac cgttgacgtg ctggcccggc tcgggtgcct gccgggccca
     7741 gcgggccgcc tcggccggac tgaccccctc ggtggtcagc cggcgcatga tctccagacg
     7801 ggccaggtcg tccggggtgt accggcggtg gtgccccggc acgtggtggc tgggcccgag
     7861 cccgtaccgc tggtgccagg tgcgcaacgt ggtgaccgcg acccccagcc gacgggccac
     7921 cgcgcccgcg ctcagcgcct catcggccac ccgacggctc cgtgggccgg agcagccggt
     7981 cgagcacgcc gcccagccag ggcgcgtacg accgggggtc gacgtccagg tcggccgcga
     8041 cggttgccgg gtccgcccag cgcagctcgg ccacctcggc cgggtccggt cggggcgtca
     8101 cccccgccgg caggctgccc cgcagcacgt ggtcgtactc gaactcgacc cggccggtga
     8161 gcgggtcctc ggcgtagtag acgtacacgc cgatctcggt cagctcgacc ggctcgacgc
     8221 ccagctcctc gccgagccgg cggttggcgg cctcgacaag tgactcaccc ggcagtgggt
     8281 ggccgcagca ggagttcgcc cagcgcaacg gaaaacgggt cttgacctcg gcgcggcgtt
     8341 gcagcagcac ctgtccggcc ggatcggtca gcagcaccga gaaggcccgg tgcagccggc
     8401 ccggcggctc gtgggcggtc gacacggtct cctcgccgat cgcctggccg gcgtcgtcga
     8461 ccagctcgac caggtgtccc tcccgggacg tcatgaggca cctccggtga cgcgggcggc
     8521 agccagtttg ccggagatga gcaccatcgg cacaccgaca ccgggctggg tacccgatcc
     8581 tacgaagacc acgttggaca gtgtgcggtg caggttggac gggcggaacg gcccggtctg
     8641 gaagaggctg tgcgcggcgg cgaacggggt gccggcggcc atgccctgct ccgcccactg
     8701 ggccggggtg atcgcccgga gcacctcgac gccgtcaccg aagccgacgt acccgcgctg
     8761 ttccagggtg tcgatcagct ggtcggagta gcggcgggtg aggtcgccgg gccagtcgaa
     8821 gggggccttc tccaggttcg gcaccggggc gagcacgtag taggtgtgcc cgccggccgg
     8881 tgcgaccgac gggtcggtcc ggctcgggtt ggtgaccagc agggacgggt cgctcatcag
     8941 ctcgccgcgc cggatcacct cgtcgaaggt gcccttccag ggccgaccga agtggatgtt
     9001 gtggtgggcg atcttccggt agccctgtcg ggagccgacg tgcagcacca cgcaggaggg
     9061 cgagtaggtg agccggcggg tgcgggtcgg cggtagcagg tcgcggtagg ccaccggcag
     9121 gtcggggttg agcaccacca cgtcggccgg gatgaactcg ccgtcggcgg tggtcacgcc
     9181 ggtggcccgg ccgtgggcgg tctccacccg ggtcaccgtg gtgtcgtacc ggaactggac
     9241 gccgtgcttc tcggcggcgc cggccatgcc ccgggagacc gcgtggatgc cgccgcgcgg
     9301 gaagtagacc ccggccaccg agtccaggta cgcgatgacc gtgtagatgg ccagcgcgtc
     9361 gtgtggtgcc agtccggcgt acatcgcctg gaaggagaag atccgctggg tacgggggtc
     9421 ccggaagaac tggttgatct tggtctggag tcggcggaac gcgcccgagg cgagcagctt
     9481 cagcaggttg ccggtgagca ggtcggtcgg ggcgtccagg ttgcgctcga tgaagtcggc
     9541 ccgctccaac tgccacagcc gccgggcgta gtcgacgaac cgcaggtagc cgtcggcctc
     9601 ccggggacca cacacccggg agatctcggc ggccatccgg gtggtgtcgg tgatcacgtc
     9661 cagcgtggag ccgtccgggt agtacgcccg gtacgccggg tccagcggca tcagctcgac
     9721 ccagtcggag agctgctcac ccaccgcgtc gagggcctcg gctatcaggt ccggcatggt
     9781 gagcacggtc ggaccggtgt cgaactcgta cccgtcgacg ctgagccgcc cggcccgccc
     9841 gcccggcacc ggttcccgct cgaccacggt cacctgccgg ccgctgccgg ccaggtgcag
     9901 cgcacaggcc aacccaccca gaccggcgcc gacgaccacc acccggtctg tccgtccgtt
     9961 caccgtccgc acgccgccca cctcctggaa agactgctca tcatgcctgc cgccgggtgg
    10021 cggccgtggc cagaccgaca agcgcggtac gcgccgtctc gtcgatcggt gcgaggtcca
    10081 gcgcggccag cgcctcggac acccggtcgg cgatcatctg ctcgatccgg tccaccgccc
    10141 cggtggtggc caccacctcg gcgaggtcgg cgatctcccg ctcgtcggtg gcaccaccgg
    10201 cgcggtccag ggcccgccgc tgcgccggat cggcggcctg gcgggccaac atcagcagcg
    10261 cggtgggctt accggtgcgc aggtcgtcac cggccggctt gccggtccgc gccgggtcac
    10321 cgtagacgcc gagcaggtcg tcgcggagct ggaacgcctc gcccacggcc aggccgtagc
    10381 gggtgtacgc gacacccagc ggctcgtccg ggccgacacc ggccaggcag gccccgaaga
    10441 gcatcggccg ttgcacggtg tagctggcgg tcttgtaccg ggccacccgc agcgcccggt
    10501 ccaccgacca gttcgccgcg tcgctctcac cgagcacgtc gaggtactgc cccgcgatcg
    10561 tctcgacccg catctggtcg tagcagcgtc gcacgtcgag cagccggtcc gcgccgacgg
    10621 cggcccgcgc gagcaaccgg tcggcccaga ccaggcagag gtcaccgacg agcaccgcga
    10681 ccgagtcgcc gaaccggtcg gggtcgccgc gccgaccggc ggcgacgtgc tgcgcggcca
    10741 gcgcccggtg ggcggtcggc cgcccccggc gggtcgccga ggcgtccatc acgtcgtcgt
    10801 ggaccagggc gaaggtgtgc agcagctcca gggcggccag cgcgggcagc accgccggca
    10861 gcggagtgtc cccgccggcc acgccgcgcc agccccagta ggcgaaggtc ggacggaccc
    10921 gcttgccgcc ggagagcacg cactcccgcg cggtcgccgc gaagccgccc atggctgcgt
    10981 cgatagcccg cagcgattcg acctcgtcgg agaggaaggc ggccagggtg tggtccaccg
    11041 cctcgaccag gtcccgcgtg tacgcggcga gcaccgcgcc caccggatcg tcgccctcgg
    11101 tcggccggtc cgccgtcagg cggaggtcat tttccgctac tgcgtcgttg gccatgtgga
    11161 cgagcgtacc ctagggttac gagttgcgtc gattggtgcg tcgaattcga gggagggcca
    11221 cggtggacat cgacctcacc gctgcctatg accgctgtcg tgagctgcac agacggcatg
    11281 gccgcaccta ctatctcgcc acccgcctgc tgcccgcatg gaaacggcgg catgtgcacg
    11341 ccctgtacgg cttcaccagg tacgccgacg agatcgtcga ccgcaccgag gacctgcccc
    11401 cggccgagcg ggccgcccgc ctcgacgact gggccggccg gttcctcgcc ggactgcacg
    11461 gcgagccggt cgacgacccg ctgctgcccg ccgtgctgca caccatcgcc gtcttcgacc
    11521 tggaccggga cgactttgcg tcgtttctca agagcatggc gatggacctg accgtcacct
    11581 cgtaccgcac ctacgacgcc ctgctcgact acatggaggg ctcggcggcg gtgatcggca
    11641 ccatgatgct gccgatcctg ggcagctccg atccggcggc ggcccgcgag ccggcccgcc
    11701 agctcggctt cgccttccag ctcaccaact tcatccggga cgtcggcgag gacctggacc
    11761 gggggcgcac ctacctgccc gacgaggacc tggccgcctt cggcgtcacc cgcgacgacc
    11821 tgctcgccgc ccgcgaccgg ggtgccggca ccgaggcgat ccgcgaactg atccggtacg
    11881 aggtacgccg ggcccaggcg cactacgtgg ccgccgctga cgggatcacc ctgctcgacc
    11941 ccgcctcaca ggcctgcatg cgcaccgcct acgccctcta cggcggcatc ctcgacgagg
    12001 tggccggcca ggaccacgac gtcttcgtcc ggcgggccac cgtgccgcag cgtcgccgga
    12061 tgtcggtggc cgcccgttcc ctgctcaccc ccaccggcac ccccgtggtg gtccccggcc
    12121 ccgacctggc cgggccgctg gccgaggcgg acgccgtgcc ggcaccccga ccggtgggcg
    12181 gctgacctcg gtgcgtaccg cgatcgtgtt gttcacccgc gacctgcggg tgcacgacca
    12241 cccggcgctg gccaccagct gcgcggcctt cgaccgggtg gtgccgacct tcgtgctgga
    12301 cccggcgttg gccgaccggt caccgaaccg gacccgcttc ctgcgccaga gcctcgccga
    12361 cctccgcgag aacctgcgcg gactcggcgg tgacctggtg ctgcggcagg gcgacccggt
    12421 gaccgagacg atcaggctgg ccggtgaggt gggcgccgag gcgatcgcgg tctccgccga
    12481 cgtcagccgg tacgcccgcc gccgcgaacg ccggctgcgc gccgagtgcg aacggcaccg
    12541 cctgcacctg cgtctcttcc ccgggctgac cgtggtcgac ccgggcgcgc tgcgccccgg
    12601 cggtggcgaa cactacaagg tgttcagccc gtacttccgg gcctggcagg gcgcgcagtg
    12661 gcggaccgcg ctcgcccggc cggagcggat cgagctgccg accggggtgc cggtggggcg
    12721 gctgcccgcc ctgcccgccg gtgcgtcacc ggacgccgcc gccgggggcg agaccgtcgc
    12781 ccgccgccgg ctgcgcgact ggctgcccaa cctcggcggg tacggcgacc agcacgacga
    12841 cctggccgcc gacgacacct cccggctcag cccgtacctg cggttcgggt gtctgtcccc
    12901 cctggaggtg gtcgagcggg tggccgaccg cgccgacccg ttcgtccggc aggtctgctg
    12961 gcgggacttc tactaccagg ccgccgccgc cttccccgac ctggaccgca ccgccttccg
    13021 cgccggcgtc accgaggact ggcggtacga caccgacgcg ctggacgcct ggaccgaggg
    13081 ccggaccgga gtgccgatcg tggacgccgg gatgcggcag ctgcacgccg aaggatggat
    13141 gcacaatcgg gcccggctga tcaccgccgg ccacctgacc aagcagctcc ggctggactg
    13201 gcgggccggg ttggcggtct tcgggcattg gctgctcgac ggcgacgtgc ccaacaactc
    13261 aggcaactgg cagtgggtgg ccggcaccgg ccacgacacc cgcccgtacc gggggttcaa
    13321 cccgatccgc caggcgcacc ggtacgaccc cgacggcgcg tacgtccgac gctggctgcc
    13381 ggagctggcg gcgatcgagg ggggtgccgt gcacgagccg tggcggctgc ccgacgcggt
    13441 acgccgtacc ctcgactacc cgccgccgct gcccccaccg gggccacccc caccctggct
    13501 gcgttgaacc acgacggcct cccgtccgta gcacctccga cccgtgaccc caccggaagg
    13561 aggcagacca gtgccgagaa caggttcagg cggcggctcg tccgcatcga gtcagtcaac
    13621 cagtcagcgc cacacagggg agttgacagc ctggctcgac gactccacga aggctgattt
    13681 cgacacattc atcgccggtc tggaaccaga cttcgcctcg cagccgctga cgcgtgcgta
    13741 cgtcaaagag ctgcaaaagc ttggtaagca gtaccgacta ctgcgcgacg ccgccgagcg
    13801 gaatccagcc tctgtggacc agcagagcct ggtcagggct taccaaccca tcgcgcagaa
    13861 gaaagaagaa ctcaacgagt acgtgcggga tttcatctac acgccggaga gttcaccgga
    13921 gcccgctccg gtgaatccgc aggcctccac cgggatgccc gctccgccac agccacaggc
    13981 cggcgccgag cagcgtgccc gtccggcgat tccggtgttc aaccccgcgt cgcaggactg
    14041 ggccgccgcc accggcccgg gttggcccgg gggcacgagc ggtgccgcac agagcagcac
    14101 cccggccggc cgggcacccg atcagccccg aagccggggc ggaaggaacc gctgatgacg
    14161 tggacgatcg tctaggatga ggcccatgag cgcggagacc gtgggccggt acatgcctgc
    14221 cgtcgtgacg ctcggtgacc tcgcggcgat gaacgccgcc gacccgaacg gccaccggta
    14281 cgagaccagc cctgagggag tcctctcggt catgccgccg cccgactccg agcacgccat
    14341 gatcgccagt cgggtcttcg cctggctgat catggcgggt tggccggcag agcaggtgct
    14401 ccaggctgcc ggcatccgca tcaccgggcc cgcaggtgac ggcggccgca ttcctgacct
    14461 caccgtgtgg cgcaagccgc caccgcgtgg agtctggtcg gcgacggacg gtctgttggc
    14521 ggtggtcgag atcgtctcgc ccggttctga ggcgatgtac tcggtcacca aggtccggga
    14581 gtacgcctcg gccggcatcg gacagtactg ggtggtggag cgggacagcc gacagaccgt
    14641 caccctgcac cggctggtcg gtgacgctta ccaggagcag gcccggatgc cactgtcctg
    14701 gctgctccag acggcacccg gcgaacacct cgacactccc tgaccgcctc cctggtggtg
    14761 tgggtgccga tcgggtcggt cggaacgtga gcggggtggc cgcaggacgg tcgatgggtg
    14821 atgctgtcgg gatggctgag ccggaacttg tggacgtggt cgtggtcggg ctgggcgtgg
    14881 gcggcgacga ggtcgccggc aagctcgccg aggctggcct gagcgtcgtc ggcatcgaac
    14941 gcgatctggt cggcggggag tgcccgtatt ggggctgcgt gccgagcaag atgatgatca
    15001 gggcggccaa cgcgctcgcc gaggcccgcc gggtggacgg gctggccggc acggcgcagg
    15061 tgcgcccgga ctggtccccg gtggcgaagc ggatccgcga ggaggccacc gacacctggg
    15121 acgaccgggt cgcggtggac cgcttcgtcg gcaggggcgg gacgttcgtc cggggcagtg
    15181 gacggctcga cggccccggc cgggtccggg tgggcgaccg ggtgttccag gcccggtacg
    15241 gcgtcgtgct cggcaccggc acccgcccct cgatcccgcc gcttcccggg ctggccgaca
    15301 ccccgtactg gacgaaccac caggcgatcg aggtcgagga gctgccggcg agcctgctca
    15361 gcctcggcgg tggcgcgatc ggtctggagc tggcgcaggt cttcgcccgg ttcggcgtac
    15421 aggtgacggt gctggagcgg tccgagcggg tgctcgcggt cgaggagccg gagtcctccg
    15481 aggtggccgc ggcggccctg cgcgccgacg gcgtgacgat cgagaccggg gtcggggccg
    15541 aacgggtcag ccacgacggt cagcacttca ccgtgcacgc cgccggtggc gcggagttca
    15601 ccgccgagcg gctgctggtg gtcaccgggc ggcgggccca cctggcggag ttgggcctgg
    15661 acaccgtcgg gatggacccc gaccagcggt acctgccggt cgacgaccgg atgcgcgccg
    15721 gggacgggat ctgggccgtc ggtgacctga ccggcgaggg cgcgttcacc cacatcgcca
    15781 tgtaccaggc ggccatcgtc gtcgccgacc tgctcgacca cgcccgccgg gccaccgccg
    15841 gccccgaccc cagcggtacg gccagcgtgg tcggcggcgc ggtcggcgcg gccagcgggg
    15901 tcccggccgc cggtgggccg gcctcagccg ggtcgggtac ggccgggtcg ggtacggccg
    15961 cgtcgggtgc ggtcgggtcg ggtgtggccg ggtcgggtgc ggtcggggcg ggggtcggcg
    16021 ggccgcaggg cgtggcgcgg gccgactacc gggcgctgcc ccgggtcacc ttcaccgacc
    16081 cggagatcgg cgcggtcggg ctcaccgaac ggcaggcccg cgaacgcggc ctcaacgtgc
    16141 aggtcggctt cgccgagttg gcctcgtcga cccggggctg gatccaccgg ggcgatggct
    16201 tcatcaagct ggtcgccgac gccgaccggg gcgtgctggt cggggccacc tcggccggtc
    16261 cggccggcgg cgaggtgctc gccgggttgg tcgtggcggt gcacgcggcc gtcccgatca
    16321 gccaactccg gcacatgatc tacgcgtacc cgaccttcca ccgggccatc gagaccgccc
    16381 tgcacgacct gaggtgatcc cgtgccggcg ccgatcggcc cggccgaatt gggccggggt
    16441 ggggggtttg gggtggaagg tggcggggag ttggtgtggg tgcgagcatt cctgacgaag
    16501 atcgagcagg ccagggcgtt ggaccgggtg ggcgaccggg tgcagcgtgt cgtcgagtcc
    16561 accctgcgcc cgcagcgggt ccgtgacctg ctgcacggcg tctggctggg tcatccgctg
    16621 catccggcga tggtgcaggt gccggtgggg gcctggatca gcgccgccgt ggtcgacctg
    16681 ctgccggggc agcgccgcgc agccaccgcg ctggtcggcc tgggcaccgt cagtgcggtg
    16741 ccggcggcgg tcgccggctt caacgactgg gcggccctct cccgcgacca gcgtcgggtg
    16801 ggcctggtgc acgccgccgc caatgtggtc ggcctggccc tctactcggg gtcgttggcc
    16861 gcccggctga ccggccggca cggtaccggc cgggccctga gctacctggg gttgggcgcg
    16921 gtcagcgccg gggcgtacct cggtgggcac ctggcctaca cgcagggcgc acaggtcaac
    16981 cagagcgtct cggagctgca ccggatcagc gaggggtggc acccactggg cgagctggcc
    17041 gcgctgccgg accgcgagct gctcacccgg gaggtcgacg acgtctcggt gatcctctac
    17101 cggcacggcg acgaggtcac cgtcatgctg gagcgctgtc cgcaccagag cggcccgctc
    17161 ggtgagggtg aggtccagca gatcgacggg catgcctgcg tcgtctgtcc ctggcacggc
    17221 agcgccttcc ggctcaacgg cggcgaggtg gtgcacggcc cgtccggcaa cgaccagcag
    17281 accctgccga cccgggtggt cgagggcgtc ctggagaccc gcctgccctg acggtcctcg
    17341 ctcgccccga cggtcccgcc tgcgacggtc ccgcctgcga cggtcccgcc ctgaggagtc
    17401 tcggcccgcc tctgcgatgg ccggcagtgt cccgtcgtcc gctggcgact cgccgtcggg
    17461 tcgcacggcc gggggccgct ggcgaccgcg ggcacccggc ccgccgccac ccggagctgg
    17521 tgcacatgtc gcgccgtgag cggggtaccc cgctatacca aaagcgttaa gagggggccc
    17581 ttccttacac ctcagtcgcg gcggtggcgg ccgctggggt tggtgaggcc ggggtggggc
    17641 gcgggtggtc ggggtgccgc cggccggcgg cgcaggccga gtacggcacc gatctgcgcg
    17701 ccgacgatgc tggccacggc gaggaccgcg gagaccgcta gcggccggtt caccccgtcg
    17761 ccgtcggacg cgcgggacgc cccgaccgcc atcaccggcg agccggaggt gtggtcggtc
    17821 gacggcggga ccaccggcgc gggctgctcg gccgacggtg gggaggcctc cgcaccgggg
    17881 gcggtcgagg ccgggccgcc gggggcggtg ggtggctgcg ccggggcgtc gtgaccgggc
    17941 ggggccgcct cggccggccg ggccaccagc cggccactcg cgtgcgcccg ggagccctgg
    18001 tcgtcggcgg tggtgggcag cttcagcaac tggccgggcc ggatccggtc cgggtcgcgc
    18061 agccggttca gcttcgccac ctcgcggtag tcgccgaagt cgtccaggta ccgctcggcc
    18121 accgtgccca ggtagtcgcc cctggccacc cggtacaccg gcgcgtcgac ctcggccgtg
    18181 cggtccgcgc cggccaactg cgccgtgcgg tccaggccgg ccagtcggac cgacccgccc
    18241 acgccggagt ccgggtaccc cgcacgttcc ggcccgacct gcgtgacgct ggcgggcgag
    18301 ctggccgccg ggtacggacc ggccagggtg gtcgccgcgg tcgctgccgg gctggccgcg
    18361 atgatcaggg cgatcgagcc gaccagcgcg gcggcggcct tctgctggcg gcgcatcccg
    18421 ggcagcttgg gcgccggccg gcggaaggtc tgcgccacca gctccaccag tacggagaag
    18481 gcgaacgtcg cccagccgaa ccagcccacc agggccaacg cccgcaggaa gagctgcccg
    18541 tcgtcacggc tggtgagggt gctgccgacc tcggcgaggg tgggcaggtg gtcggggagg
    18601 ggattgccgg ccagggcgac gagcgccaac ggcccgccga ccagcaccgc gccgagcacg
    18661 gtcagcgcgc cgagtccggt gaggacctgt cccgttcgtc gtacggcggt gccacgcgga
    18721 gctgtcatcg gaatccttcc tacggaccct cggtgagggt gcgtgcggtg gcctcaccgg
    18781 agacggtgac gctgtcgccg aagccgaaga ggccgagcag tagccggtcg taggcgacgt
    18841 cgacccgtac ccggatgtgc ttttcgccct cgatcaccgg aaagctgacc gagtggctgg
    18901 ccaccccggc ggcggccagg tagctgcgga cggccgcgcg ggcgtcgtcc tcgtcgatct
    18961 ccttgctgcc accggcgatg gcgcgggccc ggtcgatgga ctggccgccg gtccgggccg
    19021 cctcggcggc caggttctcc gcccgctgca tcgaccggag ctggccggag ccgtcgaagg
    19081 ccaacccgat gacgacgagg acgccggcca tggcgacggc caggaagagg cttacccgtc
    19141 cggcgtcgcc cgtcggctcc gccgcaccga ccgaccaccg gcggcggttc acggtcggct
    19201 ccggtagcgg tcgaggggcg aggtgaaggc ggccgtgacc gtgcgcctgg tcggcatgcc
    19261 gggtatcgcc ggcaggttga ggtcggtgaa ggagaccgtg caggtgaccc gtacggtcac
    19321 cgcgctggac tcgcccaccg cgctgtcgaa ggcgtcgtcg aaggtggccg gccgaccctc
    19381 caccgatccg gtgaaggtca ccgccggcgc gcccgtgcag ctcaacccgg accagtccag
    19441 ctgctcacgg gccgctctgc gggccgccgc ctcggcgctg tcggcgtccc gggagatcga
    19501 cgcggcgcgg gcggcgtggt gggcggccga gtcgatcgcc tcggccgcga tcgcggtccg
    19561 accggcgacg ccggccagca cgatcaacga caggaaggcc ggggccagga tcgtcacctc
    19621 gacggagacc gacccccggt cggaccggcc gctcactgcg gatccccggt ggtccaccgc
    19681 tccaccgtcc cgtgggccgt ctgccggacc gggaagctga cgcccgggac cagcgacagg
    19741 gaacgaccgg tgaccgtgca ggtcacctcg gtctcggtgg tgacgcaccg cgggccggcc
    19801 cgctcccagc cgaccagcca gtcgccggcg gcggtcagga acccggtcgc ccgtgcctcg
    19861 ccggccccgg ccggggcctg gtggacccgt tgcgcgttga ccccgctctg ggcggcgttc
    19921 agcgcggtgg cccgcgcgac gaaccaggcc gccgcctgga tcgaggcgaa gagcagcagc
    19981 aggatcagcg gcatcaccac cgccaactcc accgggctgg ccccccggtc cgccccggag
    20041 gccaccgcgg cggtgaccga cgccggccgg acccgggtcg gcccaccagg cggacccggc
    20101 accggggtgg cgacgggcgt gcggtggcac cgggcggccg gggccgcccg gtcgtgggcc
    20161 gtcggtggcg tacgcggcat cgtcgttacg gggcggccgg gccggggatg gcgtccatcc
    20221 agctcttggc cttcgtgctg accagggcgg tgaccgcgat cgcggcggcc accaggccga
    20281 agatgatcac ggcggtgggg accgggctgt ccccccggtc accggcccgg cgcagctcgg
    20341 cgagccggtc gaggaacacg atgtgcaggt aggcgacgag gcgcatggga gttctcctgg
    20401 gatggggagg ggatcacaga cgggcgacga acggatagac ggcgaagccg agcaggacga
    20461 agaccagcag cgcgcccgga atgtcgagcc ggctggtgat cccctccgcc cgggccaggt
    20521 tgtcggtacg gatctggtcg cgcagcgagt cggcgcggct gcgcaacgtc tcgtgcacct
    20581 gggcgccctc gctgccggac gaacgcatga tcgccccgac gtcgcccagc tcggggatgc
    20641 ccagcttctc ggccaggtcg cgcagctcgt cccagggtga gtgcatctgc atctgggcga
    20701 tccgcagcga ctcccgcagc cggtcgaaga cccagccgtc gcagaccatc gccgcccgtt
    20761 ccagcgactg caccggcccg tgcgcggcgg acagttgcag cgccaccaga tccaggtacg
    20821 cggagacggc ctggcggaac tcggcccgcg ccgcctccgc ccggaccagc acgtcccggt
    20881 gggcgatcag ggcgcagacc gccgccgccc ccaccgaacc gagcaccggt acgaccaccg
    20941 gcagctccgt cccggccagg aagaggacgc cactgagcag cgtcggcgcg gccaacccga
    21001 tcagggtgga gagcagcaac gagagggtgt actgctcggg cgtccggtcg atcagcgcca
    21061 actcccggtg cggcggccgt acccagcggg ccagcccacc gagccagtcc aggtgccggc
    21121 cggtacccgg tcgcgtggca cccggtggct ggtgcagccg acgcagcgcc ggcccgagcg
    21181 ccggggtggc cggcagggcc tcctggacga cgaggaacag gccgagcccg accagcccgc
    21241 cgccgaccac ggccagggtg agctgccaac tgaggatcac cgcaacgcct cctccggatc
    21301 gggggcgggc aggaaacggg ccggctgcgg tggctggctc atcgcgcgaa cccagaccag
    21361 caggccaacg aagcaggtgc cgagcacgac catcaccagt tgcccggtcg gggtgccgta
    21421 cggtcgcatg tactcggtgt tgagcagccc gtacgccagg gtcgccaggg tcatcccggt
    21481 gaggaaccgg accgcgaacc ggggctgggt gcgtttggcc tcgatctccc gccgggtggc
    21541 gacctcggcc gccgccgccc cggcgatcga gccgagcacg tcaccgaggc gctcgccccg
    21601 gtcggtgagg tgcaggatca acgcggccac cacctggtcg cagaccgggt caccgatctc
    21661 gtcggcgaag gccagcaggg cggcccgcgc cgaccagccg gcctgcaacc gggcggcgag
    21721 cacccggacc tcctcctcga tctcctccgg cacggtggtg accgtgctgg cgatcgcctg
    21781 ttggaggccc tgaccgacgg cggagacgtc cttgagccgg cgggtccact cgccgaccgc
    21841 ctcgatccgg gcgatggccc gctgctcctc ccggccgacg gcgaacagcc acggcacccc
    21901 gggcaccgcg agggcgacca gcagacccac caccggcaag ccggtcagca ggaacgccaa
    21961 cgccccggcg accactgcgc cgaccagcag ggaccggcgg cgacgctgct gccggcggct
    22021 ggtgtccgtg ccgagcaaga accgacgcag gtcgttgccc gcgccggggc gggtccggcg
    22081 cgggcggcgg gtgccgacca ccgcgacgac ggccagcacc atcccggcca cgcaggccgc
    22141 cccggaaacc accgcgacca gttcgacgtt catgtcttac cgcct
//
