LOCUS       NZ_BMMJ01000002        10816 bp    DNA     linear   CON 09-SEP-2024
DEFINITION  Micromonospora yangpuensis strain CGMCC 4.5736 sequence02, whole
            genome shotgun sequence.
ACCESSION   NZ_BMMJ01000002
VERSION     NZ_BMMJ01000002.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Micromonospora yangpuensis
  ORGANISM  Micromonospora yangpuensis
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 662800)
  AUTHORS   Sun,Q. and Zhou,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 133X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014645775.1-RS_2024_09_09
            Annotation Date                   :: 09/09/2024 04:34:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,914
            CDSs (total)                      :: 5,857
            Genes (coding)                    :: 5,698
            CDSs (with protein)               :: 5,698
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 20 of 159
            Pseudo Genes (incomplete)         :: 144 of 159
            Pseudo Genes (internal stop)      :: 5 of 159
            Pseudo Genes (multiple problems)  :: 9 of 159
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:15:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 143126
            Orig. end                         :: >153942
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMMJ01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..>10816
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..>10816
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..>10816
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:>5816](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..>5816
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            complement(251..673)
                     /locus_tag="IEY64_RS05230"
                     /old_locus_tag="GCM10012279_10660"
     CDS             complement(251..673)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007462632.1"
                     /locus_tag="IEY64_RS05230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_10660"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_091440660.1"
                     /transl_table=11
                     /translation="MVQKTAPSADLTWLLDDLVSRVKQAEHAVALSTDGLLMASSQGLS
                     RDDGEHLAAMAAGIQSLARGAGKRFGGGHVQQTIIEMQSSFLFVTAAGRNACLAVLAGE
                     EADVGLIAYEMAMLVTRVGKYVNSPARGLDLPADGR"
     misc_feature    1029..1043
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.93"
                     /tool="antismash"
     gene            1082..1327
                     /locus_tag="IEY64_RS05235"
                     /old_locus_tag="GCM10012279_10670"
     CDS             1082..1327
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287422.1"
                     /locus_tag="IEY64_RS05235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_10670"
                     /product="DUF2630 family protein"
                     /protein_id="WP_091440665.1"
                     /transl_table=11
                     /translation="MDDRNILRRISELVDEEHRLRSTAQVNEAGTADEQDRLRELEESL
                     DQCWDLLRRRRAARQAHGDPEAQGARPVSEVERYLQ"
     gene            complement(1435..2370)
                     /locus_tag="IEY64_RS05240"
                     /old_locus_tag="GCM10012279_10680"
     CDS             complement(1435..2370)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018583044.1"
                     /locus_tag="IEY64_RS05240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_10680"
                     /product="serine protein kinase RIO"
                     /protein_id="WP_091440669.1"
                     /transl_table=11
                     /translation="MREHDLPAQPRRARGRSRFDDDEPYLLKRGRPAPPVTADPGDEPD
                     PQTGDRWSSWDTAVHGPEPYPDWVVTESAARDTELGVLKTGKEADVHLLRRAVPGTDRS
                     CLLAVKRYRDANHRLFHRDAGYLEGRRVRRSRENRAMAGRTDFGRQLIAGQWAAAEFDA
                     LGRLWRIGAEFGTIAVPYPVQVLGTELMLEFLGDAEQGHAAPRLAQLRPGPVELRALWQ
                     QLVDALVVLARVGYAHGDLSPYNLLVHDGRLVMIDLPQVVDVVANPQGPEFLARDVRVV
                     AAWFTARGLPGGTADPAALTELLLREAGIR"
     gene            complement(2588..3232)
                     /locus_tag="IEY64_RS05245"
                     /old_locus_tag="GCM10012279_10690"
     CDS             complement(2588..3232)
                     /EC_number="3.1.3.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018583043.1"
                     /locus_tag="IEY64_RS05245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_10690"
                     /product="HAD family hydrolase"
                     /protein_id="WP_091440672.1"
                     /sec_met_domain="HAD_2 (E-value: 1e-10, bitscore: 37.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLLLLDLDNTLLDRAGSFRTWGQRFLDAVGAPPGDIDWLVAIDA
                     DGLTDRWDVADAIRDRYGLLIPSIDLVEELHDGALSYTRLDPLVACALRIADNAGWLPV
                     VVSNGVVRQQEALIRRTGLDRYVADWVISEEAGVSKPNPRIFALAAQRVRMPLRGAWVI
                     GDGPEADIGGATSVGLPSVWLHRGRTWSDSRFAPTHVVDGLIAAVAVVLGS"
     misc_feature    complement(3269..3283)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 26.9"
                     /tool="antismash"
     gene            3386..3958
                     /locus_tag="IEY64_RS05250"
                     /old_locus_tag="GCM10012279_10700"
     CDS             3386..3958
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788252.1"
                     /locus_tag="IEY64_RS05250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_10700"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_091440676.1"
                     /transl_table=11
                     /translation="MPRVSQDQLDARRQEILAAARDCFARHGYEGATVRRLEEATGLSR
                     GAIFHHFRDKDSLFLAVAEDDAVAMVETVARNGLVQVMRDLLARAVSPDTTGWLGSQLE
                     VSRRLRTDPAFARRWAERSAAIAEATRDRLTRQREAGVLREDIPIDVLAQFLELAYDGL
                     VLHLAMGRPAGDLARVLDLVEEAVRRH"
     gene            4081..5004
                     /locus_tag="IEY64_RS05255"
                     /old_locus_tag="GCM10012279_10710"
     CDS             4081..5004
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018802925.1"
                     /locus_tag="IEY64_RS05255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_10710"
                     /product="TIGR04222 domain-containing membrane protein"
                     /protein_id="WP_091440679.1"
                     /transl_table=11
                     /translation="MLVLAAPDDTWGISGPVFLGSYLTVAVLIVCWSLVDRARLLTGSP
                     RYGPLGAQPVAYLNGGEQLAVWAALGGLRGSGLVGVTPDRRLAVTGSLPAGATGLDVAV
                     HHAAYRRLTARQLRQDPAVRQALDALREGLRRQGLLLTPAQRRRLRRGAVLLGVLLLVG
                     LVRVLAGLANDRPVGFLLLGMAVIGVTALLLTRAPRRTRAATAALRAHRQQHVHLAPTN
                     NPAYATYGATGAAMGIALFGTASIWAADPTFAEQADIQRQTATGGGSTGGCGSGSSGDS
                     GGSSGDSGGGSSCGGGSSCGGGGCGG"
     gene            5001..>5816
                     /locus_tag="IEY64_RS05260"
                     /old_locus_tag="GCM10012279_10720"
                     /pseudo=""
     CDS             5001..>5816
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018802926.1"
                     /locus_tag="IEY64_RS05260"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_10720"
                     /product="DUF692 domain-containing protein"
                     /pseudo=""
                     /sec_met_domain="DUF692 (E-value: 8.2e-80, bitscore: 263.0,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGPAGVGIGWRPEIAGFVADLPGLRFVEVAAESIPSTGPLPAAL
                     AELRGRGVTVVPHGVRLSLGGAEPVEAARVAHLARVAELTGAPLVSEHIAFVRAGGLEA
                     GHLLPLPRSREAVAVTVANVRRAQADLPVPLALEPIAALFDWPDDELDEADFLTEILDR
                     TGAQLLLDLANVYANARNRGTDPVALLDRLPLERVAYVHVAGGAEAGGFYHDTHTDSLP
                     RPVLDLVVALCARRRPPALLLERDGHYPPAAELRAELDAIATASGHPPVT"
     misc_feature    complement(5841..5852)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.89"
                     /tool="antismash"
     gene            6014..6526
                     /locus_tag="IEY64_RS05265"
                     /old_locus_tag="GCM10012279_10730"
     CDS             6014..6526
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019868785.1"
                     /locus_tag="IEY64_RS05265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_10730"
                     /product="hypothetical protein"
                     /protein_id="WP_373868312.1"
                     /transl_table=11
                     /translation="MSTPEGTGAARAADGPSTPDGAGDLAVRQAALVAALVAGRPAPPG
                     FAPEPLAAARAALLRKRAGEVARHWPLLAAGLGPAWPGTFTGWAAGRPGNGSLRDGWDL
                     ARHLLQRDALPPLGADELAVREATVGYDGQRPPRTRRLPAVGRAGGAVALQVAGRVRLL
                     RAASRSR"
     gene            6570..7229
                     /gene="mug"
                     /locus_tag="IEY64_RS05270"
                     /old_locus_tag="GCM10012279_10740"
     CDS             6570..7229
                     /EC_number="3.2.2.28"
                     /GO_function="GO:0000700 - mismatch base pair DNA
                     N-glycosylase activity [Evidence IEA]"
                     /GO_process="GO:0006285 - base-excision repair, AP site
                     formation [Evidence IEA]"
                     /codon_start=1
                     /gene="mug"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014441762.1"
                     /locus_tag="IEY64_RS05270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_10740"
                     /product="G/U mismatch-specific DNA glycosylase"
                     /protein_id="WP_091440682.1"
                     /transl_table=11
                     /translation="MAELPDRTPSPGRRSGTAQSSPTVRPAPPAPRRARAGSPTPSREE
                     LAAAADRTIPDVVAPGLNVLFVGINPGLWSAATGRHFARPGNRFWPALHRGGFTPYQLA
                     PHEQDDLPGYGLGITNMVARASARADELTAAELVAGAEILTDTVERYRPRWVAVVGVTA
                     YRTGFGRPKATYGPQPETLGPAKLWVLPNPSGLNAHFTAETLGAAFAELRAATASR"
     gene            complement(7375..9357)
                     /locus_tag="IEY64_RS05275"
                     /old_locus_tag="GCM10012279_10750"
     CDS             complement(7375..9357)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) ABC_efflux"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019030577.1"
                     /locus_tag="IEY64_RS05275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_10750"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_091446699.1"
                     /transl_table=11
                     /translation="MPGGGMGGWSMLRSMRDRDQVTAHRLSNGTARRIVAFARPYRRDI
                     VVFLVTVVLAAIIGVATPVLAGDVINTINRGGTDAGAAVVRLALFIAGLAVLDALLSLA
                     QRWYSARIGEGIILDLRTRVYDHVQRMPLQFFNRTQTGALVSRLNNDVMGAQRAFTSTL
                     SGVVSNVIQLVLTAAVMFTLSWQITVLSLVLLPIFIVPARRVGKRLAEITRESYNLDAK
                     MNATMTERFGVAGALLVKLFGTPDEEARRFAGRAERVRDIGIQSAMYSRTFFVAMLLVA
                     SLAQALTYGLGGWLAVTGSVSAGTVVTLALLLTRLYGPLTALSNVRVDVMSALVSFDRV
                     FEVLDLRPGIEEKPGAVAVPPGNGRVEFRDVRFRYPSAAEVSLASLEEVTTLDRTINEP
                     VLKGVSFSVEPGQMVALVGPSGAGKSTLSMLVSRIYDVTDGQVLVGGVDVRDASLASLR
                     DEIGVVTQDSHLFHETIAENLRYAKPDATDDEIWAALAGAQVADLVRTLPDGLQTTVGE
                     RGYRFSGGEKQRIAIARLLLKAPSIVILDEATAHLDSESEAAVQRALSVALTGRTALVI
                     AHRLSTVRDADQILVLDGGRIVERGRHEELVAVGGLYAELYRTQFAVADSPSPYADATG
                     PEPVITTVPTSQYLAEEALPPAAAN"
     gene            complement(9531..10298)
                     /locus_tag="IEY64_RS05280"
                     /old_locus_tag="GCM10012279_10760"
     CDS             complement(9531..10298)
                     /NRPS_PKS="Domain: ECH (13-244). E-value: 1.4e-45. Score:
                     147.5. Matches aSDomain:
                     nrpspksdomains_IEY64_RS05280_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018722897.1"
                     /locus_tag="IEY64_RS05280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_10760"
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="WP_091440685.1"
                     /transl_table=11
                     /translation="MTAGSDGVRIDCAGPVATVTLCRPDVLNAQTPAMWRALVDISREL
                     PGDVRVVVVRGEGRAFSAGLDLAVAGATGPGSFAELATLPEAECAQRIAEFQAAFTWLH
                     RPDIVSVAAVQGHAIGAGFQLALACDLRVLAEDARLAMAEVTLGLVPDLAGTKRLVDLV
                     GYSRALEICATGRRMDAAEADRIGLATLVVPTAELTDAVRDLTAGLLAHDRDAVVEIKA
                     LLAGAVNRNAADQQRAEREAQTRRLRDLAGRGE"
     aSDomain        complement(9567..10259)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEY64_RS05280_ECH.1"
                     /evalue="1.40E-45"
                     /label="IEY64_RS05280_ECH.1"
                     /locus_tag="IEY64_RS05280"
                     /protein_end="244"
                     /protein_start="13"
                     /score="147.5"
                     /tool="antismash"
                     /translation="GPVATVTLCRPDVLNAQTPAMWRALVDISRELPGDVRVVVVRGEG
                     RAFSAGLDLAVAGATGPGSFAELATLPEAECAQRIAEFQAAFTWLHRPDIVSVAAVQGH
                     AIGAGFQLALACDLRVLAEDARLAMAEVTLGLVPDLAGTKRLVDLVGYSRALEICATGR
                     RMDAAEADRIGLATLVVPTAELTDAVRDLTAGLLAHDRDAVVEIKALLAGAVNRNAADQ
                     QRAEREAQT"
     gene            complement(10342..10569)
                     /locus_tag="IEY64_RS05285"
                     /old_locus_tag="GCM10012279_10770"
     CDS             complement(10342..10569)
                     /codon_start=1
                     /function="9.3 : Transcription factors"
                     /function="12 : Regulatory functions"
                     /function="16.3 : Control"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020510159.1"
                     /locus_tag="IEY64_RS05285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_10770"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_007462679.1"
                     /transl_table=11
                     /translation="MAATGTATSTEKGRRIVGAERQTLAKDLVKRYTSGESIRALAAST
                     GRSYGFIHRVLTESGVQLRQRGGARRRKKA"
     misc_feature    complement(10601..10619)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 19.05"
                     /tool="antismash"
ORIGIN
        1 cgaactgggc ggcgatctcg gcgaccgagc acacccgccg gcagagctcg atgatcgcca
       61 ggtgctccgg ccccagccct gccggggcgg gcggggcggc gggagtggtc atcaccagcg
      121 agatcagatc gaaggtgccg gtgaccgggc ggccccgacc ccgggtgacc gcgtacgggc
      181 gcaccaccgg ccccgcctgc tcgtcgaccc accggtcgtc ccacgatccg tccgcaacgg
      241 ccaccgtgga ctaccgcccg tcggcgggca ggtcgaggcc ccgggccggt gagttgacgt
      301 acttgccgac ccgggtcacc agcatcgcca tctcgtacgc gatcagaccg acgtcggcct
      361 cctcaccggc gagcaccgcc aggcacgcgt tgcgcccggc cgccgtgacg aagaggaacg
      421 aggactgcat ctcgatgatc gtctgctgta cgtggccgcc accgaagcgc ttgccggccc
      481 cccgggccag gctctggatc ccggcggcca tcgccgcgag gtgctcgccg tcgtcgcggc
      541 tcaacccctg cgaggatgcc atcagcagcc cgtcggtgga gagcgcgacc gcatgctcag
      601 cctgcttcac ccgactgacc aggtcgtcca gcagccacgt caggtctgcg ctcggagccg
      661 tcttctgcac cactcgtcgt cctcttctcc ccggctggtg tcgccgtgct cgtctcgggc
      721 ttccccacgt acccagggcg gtcgcacccg ccccgcggtc ggctcaacgc gccatcggtc
      781 ggcggtgcgg ccttcccggc ggaccggagc gtccaccggc caccagttcg gtgcggacgg
      841 accgcaccca tgccgtactc cattatggac cgccggccga gacaccggtc cgcccggtcc
      901 cggcgagcgg gatcggcgat ggccgacctt cggggttccc ggccccgacc cccgcagccg
      961 cccgaccggt ggacggtacc cgttccgggt ttcggacggg tgcacgggcg acggtacgcc
     1021 ggacgggcgg cctatccggt ccgggcgaca gtggccggtg tgctgtgcca cgctcagggg
     1081 catggacgac aggaacatct tgaggcgcat ctcggagctg gtcgacgagg aacaccggct
     1141 ccggtccacc gcgcaggtca acgaggcggg caccgcggac gagcaggacc ggctacggga
     1201 gttggaggag tccctggacc agtgctggga tctgctgcgc cgacgccggg ccgcccggca
     1261 ggcccacggc gacccggagg cgcagggtgc ccggccggtc tcggaggtcg aacgctacct
     1321 gcagtgacgt ccgccggctc ggcgctgccg cgtccgccgg tgggcgccgg gtggcccgga
     1381 cccgaagatc ggtttccggg ccacccgcgc ccaacggatg ccggccaccc gcgctcagcg
     1441 gatgccggcc tccctcagca gcagctcggt cagggcggcc ggatcggcgg tgccgccggg
     1501 cagtccccgg gcggtgaacc aggcggcgac cacccggacg tcgcgggcca ggaactccgg
     1561 gccctgcggg ttggccacca cgtcgaccac ctgcggcaga tcgatcatga ccagtcgtcc
     1621 gtcgtgcacg agcaggttgt acggggagag gtcgccgtgg gcgtacccga cccgcgccag
     1681 caccaccagg gcgtccacca gctgctgcca gagcgcccgc agctccaccg gcccgggacg
     1741 cagctgggcc agtcgcggcg cggcgtggcc ctgctcggcg tcaccgagga actccagcat
     1801 caactcggtg ccgagcacct gcaccgggta cgggacggcg atcgtgccga actccgcgcc
     1861 gatccgccag agccgaccga gcgcgtcgaa ctcggcggcg gcccactgcc ccgctatcaa
     1921 ctgccggccg aagtcggtcc gcccggccat cgcccggttc tcccgggacc ggcggacccg
     1981 acggccttcg agatagccgg cgtcgcggtg gaagagccgg tggttggcgt cccggtagcg
     2041 cttcaccgcc agcaggcagg accggtcggt ccccggcacc gcccggcgga gcaggtgcac
     2101 gtcggcttcc ttgccggtct tgagtacccc gagttcggtg tcccgggcgg ccgactcggt
     2161 gaccacccag tcggggtacg gctcggggcc gtgcacggcg gtgtcccagg acgaccaccg
     2221 gtcgccggtc tggggatcgg gctcgtcgcc ggggtcggcg gtgaccggtg gggccggtcg
     2281 accgcgcttc aggaggtagg gctcgtcgtc gtcgaagcgg ctccggccgc gggcacggcg
     2341 cggctgcgcc ggtaggtcat gttcacgcac ttgtctggtg atcccttgat cgaggctggt
     2401 ggggacggac gggaagagcc tgcgaaaaca gccatgaccg acctcctctc cactcgaccg
     2461 ggcgtcaccc gggcacgtgc cacacgcgcg ccgaccatcc tcaccgccgc cggagcggac
     2521 ggtcaaccga tttatccacc gaccggtcgg ttgcgcgctc cggcacctgc ggccggccgc
     2581 ccggcggtca gctgccgagc acgaccgcga cggcggcgat caggccgtcg acgacgtggg
     2641 tgggtgcgaa ccgggagtcc gaccaggtac gcccccggtg cagccagacg ctgggcagcc
     2701 cgaccgaggt ggctccgccg atgtccgcct ccggaccgtc accgatcacc caggctcccc
     2761 gcagcggcat ccggacgcgt tgggcggcga gcgcgaagat cctcgggttg ggcttgctca
     2821 ccccggcctc ctcggagatc acccagtcgg ccacgtaccg gtccagcccg gtgcgccgga
     2881 tcagggcctc ctgctggcgt accacgccgt tgctgaccac caccggcagc caaccggcgt
     2941 tgtcggcgat ccgcagcgcg cacgccacca gcgggtcgag ccgggtgtac gacagcgccc
     3001 cgtcgtgcag ctcctcgacc aggtcgatgg agggaatgag caggccgtag cggtcccgga
     3061 tggcgtccgc gacgtcccac cggtcggtca gcccgtccgc gtcgatggcg accagccagt
     3121 cgatgtcgcc gggcggggca ccgacggcgt ccaggaaacg ctgtccccag gtacggaacg
     3181 acccggcccg atcgagcagg gtgttgtcca ggtccagcag gagcagcggc acccgccgaa
     3241 gggtacggga ccacgctgtg tcatggacag ggccggttgg cccaccgtgg cgctgcggta
     3301 ccgccgcgta ccaccccggt caccccaacg caccaagccg tacgtacggt ttgcaccggt
     3361 ccaccgcacc tgacacgatc gtcaggtgcc cagagtaagt caggaccagc ttgacgcccg
     3421 acgacaggag atcctcgccg cggcgcggga ctgtttcgcc cgacacgggt acgagggggc
     3481 caccgtccgg cggctggagg aggccaccgg cctgtcccgg ggggcgatct tccaccactt
     3541 ccgggacaag gactccctct tcctggccgt cgccgaggac gacgcggtgg ccatggtgga
     3601 gacggtggcg cgcaacggtc tggtccaggt gatgcgcgac ctgctggccc gtgcggtctc
     3661 cccggacacc accggctggt tgggcagtca gctggaggtc tcccgccggc tgcgtaccga
     3721 tccggccttc gcccgccggt gggccgagcg gtcggcggcg atcgccgagg cgacccggga
     3781 ccggctgacc cgccagcggg aggccggcgt gctgcgcgag gacatcccga tcgacgtcct
     3841 cgcccagttc ctggagttgg cctacgacgg cctggtgctg cacctggcca tggggcggcc
     3901 cgccggcgac ctggcccggg tgctcgacct ggtcgaggag gcggtccgcc gccactgacc
     3961 ccggtcccgg gccagccgca ccgacctccg gtccgccggc accgaccggc gggaccgtgg
     4021 gtggcggggc tggcccacaa tgggcgcacc cctgccacgt gtgaccacag gagccgacac
     4081 atgctggttc tcgccgcccc ggacgacacc tggggcatct ccggtccggt cttcctcggg
     4141 agctatctga cggtggccgt cctcatcgtc tgctggtcgc tcgtcgaccg ggcccgtctg
     4201 ctcaccggat cgcccaggta cggcccgctc ggcgcgcagc cggtcgccta cctcaacggc
     4261 ggcgaacaac tcgccgtctg ggccgccctc ggcgggctgc gcggcagtgg tctggtcggc
     4321 gtcacgccgg accggcggct ggcggtcacc ggcagcctgc ccgccggtgc caccggcctg
     4381 gacgtggcgg tgcaccacgc ggcgtaccgc cggttgaccg cccggcagct gcgccaggac
     4441 ccggcggtgc gtcaggcgct ggacgcgctg cgggaggggt tgcggcgaca gggcctgctg
     4501 ctcaccccgg cccagcgtcg tcgactgcgt cggggcgcgg tactgctcgg cgtgctgctc
     4561 ctggtcggcc tggtccgggt cctcgccggc ctggccaacg accggccggt cggcttcctc
     4621 ctgctcggca tggcggtcat cggggtgacc gccctgctgc tgacccgggc gccccggcgg
     4681 accagggccg cgacggccgc gctgcgcgcc catcgccagc aacacgtcca tctcgccccc
     4741 accaacaatc cggcgtacgc cacctacggc gccaccgggg ccgcgatggg gatcgccctg
     4801 ttcggcaccg cctcgatctg ggccgccgac cccaccttcg ccgagcaggc cgacatccag
     4861 cggcagacgg ccacgggtgg tggctccacc ggcggctgcg gcagtggctc ctccggggac
     4921 agcggtggtt cctccggcga cagcggcggt ggctccagtt gcggtggtgg ttccagctgc
     4981 ggcggcgggg ggtgtggcgg gtgaccggac cggccggggt gggcatcggc tggcggccgg
     5041 agatcgccgg cttcgtcgcc gacctgcccg gactgcgttt cgtcgaggtg gccgccgagt
     5101 cgatcccgtc gaccgggccg cttcccgccg ccctggccga gctgcgtggg cggggtgtca
     5161 ccgtcgtacc gcacggggtg cgactctccc tcggcggcgc ggaaccggtc gaggcggccc
     5221 gggtggcaca cctggcccgg gtcgcggagc tgaccggggc cccgctggtc agcgaacaca
     5281 tcgcgttcgt ccgggccggc ggcctggagg ccgggcacct gctgccgttg ccgcgcagcc
     5341 gggaggcggt ggccgtcacc gtggccaacg tgcggcgggc ccaggccgac ctgccggtcc
     5401 cgctcgccct ggaaccgatc gcggcgctgt tcgactggcc ggacgacgaa ctggacgagg
     5461 cggacttcct gaccgagatc ctcgaccgga ccggcgcgca gctcctgctc gacctcgcca
     5521 acgtgtacgc caacgcacgc aaccggggca ccgacccggt cgccctgctc gaccggctgc
     5581 cgttggaacg cgtcgcctac gtgcacgtcg cgggcggcgc cgaggcgggc ggtttctacc
     5641 acgacacgca caccgattcg ctgccccggc ccgtactcga cctggtcgtt gcgctctgcg
     5701 cgcgccggcg tcccccggcg ctgctgttgg aacgggacgg ccactacccg ccggccgccg
     5761 agctacgcgc cgaactggac gccatcgcca ccgcctccgg ccacccgccc gtaaccccca
     5821 ccggtaagga agggccccct gttaacgctt tcggtataga agggaacccc ttttgcctgc
     5881 cgagtggcgg agctgaactc ggccatccgg cggcgggcgc accgggccat ccggcggcga
     5941 gcacaccagg tcatccggcg acgggcacac cgggccggcc ggcgacgggc gtaccgggcc
     6001 ggccggtggc gatgtgagta cgccggaggg gaccggcgcg gcgcgggccg ccgacgggcc
     6061 gagcaccccc gacggtgccg gtgacctcgc ggtccggcag gccgcgctgg tcgccgccct
     6121 ggtcgcgggt cgaccggccc cgccgggctt cgcgccggag ccgctggccg ccgcccgcgc
     6181 cgccctgcta cgcaagcggg ccggggaggt ggcccgacac tggcccctgc tcgccgccgg
     6241 cctcggtccg gcctggccgg gcaccttcac cgggtgggcc gccggccgcc ccggcaacgg
     6301 ttcgctgcgc gacggctggg acctcgcccg gcacctgctc caacgggacg ccctgccccc
     6361 gttgggcgcc gacgagttgg ccgtccggga ggccaccgtc ggctacgacg ggcaacgacc
     6421 cccgcgtacg cggcggctgc cggcggtggg ccgggccggc ggtgccgtcg cgctccaggt
     6481 cgccggtcgg gtacgcctgc tgcgggccgc cagccgttcg cggtgacctc gaccgcgacc
     6541 ccggtcaccg ggtacggcag gatcaccaca tggccgagct acctgaccgg actccctccc
     6601 ccggtcgacg gtcgggcact gcgcagtcgt cgcctaccgt gcggccggcg cctcccgcac
     6661 cgcgccgggc acgcgcggga tcgcccacgc cgagccggga ggagttggcg gcggcggccg
     6721 accggaccat cccggacgtc gtcgcgcccg gcctgaacgt gctcttcgtg gggatcaatc
     6781 cggggctgtg gtcggccgcc accggccggc acttcgcccg gccaggcaac cggttctggc
     6841 ccgccctgca ccggggtggc ttcaccccgt accagcttgc cccgcacgag caggacgacc
     6901 tgcccggcta cggcctgggc atcacgaaca tggtggcccg ggccagtgcc cgcgccgacg
     6961 agctgaccgc cgccgaactc gtcgccggcg cggagatcct gaccgatacc gtcgagcggt
     7021 accggccccg ctgggtggcg gtggtcgggg tgaccgcgta ccggaccggg ttcggccggc
     7081 cgaaggccac ctacggaccg caaccggaga cgctgggccc ggccaagctg tgggtgctgc
     7141 ccaacccgag cggcctgaac gcgcacttca ccgccgagac cctgggtgcc gccttcgccg
     7201 agttgcgggc ggcgacggca tcccggtgac cggtccgccg ccgggcggcg gagtgaccgg
     7261 gtggccgccg ggcggcggag tgaccgggtg gccgccgggc ggcggagtgg ccagttcgcc
     7321 accgggcggc ggagtgaccg gtccgccgct gggcggccgg gctgctcctg ctggtcagtt
     7381 cgccgcggct ggcggcagcg cctcctcggc gaggtactgg ctcgtcggca cggtggtgat
     7441 caccggctcg gggccggtgg cgtcggcgta cgggctgggc gagtcggcga ccgcgaactg
     7501 ggtccggtac agctcggcgt agagcccgcc gacggccacc agctcctcgt gccggccccg
     7561 ctcgacgatg cgtccgccgt cgaggacgag gatctggtcg gcgtcgcgga cggtggagag
     7621 ccggtgcgcg atcaccagcg cggtacgccc ggtcaacgcc accgacaggg cccgctgcac
     7681 cgccgcctcg ctctcggagt ccaggtgtgc ggtcgcctcg tcgaggatca cgatcgacgg
     7741 ggccttgagc agcaaccggg cgatggcgat gcgctgcttc tccccgccgg agaagcggta
     7801 gccgcgctcc ccgaccgtgg tctgcaggcc gtcgggcagc gtccggacca gatcggcgac
     7861 ctgggcgccg gcaagcgccg cccagatctc gtcgtcggtg gcgtcgggtt tggcgtagcg
     7921 caggttctcc gcgatcgtct cgtggaagag gtgcgagtcc tgggtcacca ccccgatctc
     7981 gtcccgcagc gaggcgaggg aggcgtcgcg gacgtccacc ccaccgacga gcacctggcc
     8041 gtcggtgacg tcgtagatcc gggagaccag catggacagg gtggacttgc cggcacccga
     8101 gggcccgacc agggccacca tctgacccgg ctcgacgctg aacgagaccc ccttgagcac
     8161 cggctcgttg atggtccggt ccagcgtggt gacctcttcg agggaggcca gggagacttc
     8221 ggcggcgctc gggtaccgga accggacgtc gcggaactcg acccggccgt tgcccggcgg
     8281 caccgccacc gcacccggct tctcctcgat gcccggccgc aggtcgagca cctcgaagac
     8341 ccggtcgaag gagaccaggg cgctcatcac gtcgacccgg acgttcgaca acgcggtgag
     8401 cgggccgtac aggcgggtga gcagcagggc cagcgtcacc acggtgccgg cgctgacgct
     8461 gccggtgacc gcgagccagc cgccgagacc gtaggtgagc gcctgggcca gcgaggcgac
     8521 cagcagcatc gcgacgaaga aggtccggga gtacatggcg gactggatgc cgatgtcgcg
     8581 gacccgttcg gcccgcccgg cgaaccggcg ggcctcctcg tcgggggtac cgaagagctt
     8641 gaccagcagc gcgccggcca cgccgaaccg ctcggtcatc gtcgcgttca tcttggcgtc
     8701 gaggttgtac gactcccggg tgatctcggc cagccgcttg cccacccgcc gggccggcac
     8761 gatgaagatc ggcagcagca ccagcgagag cacggtgatc tgccaggaga gggtgaacat
     8821 caccgcggcg gtgagcacca gctggatgac gttgctgacc accccggaca gggtcgaggt
     8881 gaaggcccgt tgggcaccca tcacgtcgtt gttgagccgg ctgaccagcg caccggtctg
     8941 ggtccggttg aagaactgca gcggcatccg ctgcacgtgg tcgtagaccc gggtccgcag
     9001 gtcgaggatg atcccctcgc cgatgcgggc ggagtaccac cgttgggcca gcgagagcag
     9061 tgcgtcgagg acggcgagcc cggcgatgaa cagcgcgagg cggaccaccg ccgccccggc
     9121 gtcggtgccg ccccggttga tcgtgttgat cacgtcgccg gcgaggaccg gcgtggccac
     9181 cccgatgatc gcggcgagca ccaccgtgac caggaagacc acgatgtcgc ggcggtaggg
     9241 ccgggcgaac gccacgatgc gccgggcggt gccgttgctc agtcggtggg cggtgacctg
     9301 gtcccggtcg cgcatcgacc ggagcatgct ccatccgccc atgccgccgc cgggcatcgg
     9361 gttcgccacg tatcacctcc gggtcgtcgg gccgccaggt ccattctccc gacgtgtacg
     9421 acaacctcgg cggtaacctg gctcttcccg agcggtcctt actatccggc acgaccgaaa
     9481 cggccgccag tcggggcgac ccggcccgtg cccgggcacg tccggctcgg ctattccccg
     9541 cgtccggcca ggtcacgcag ccgacgggtc tgcgcctccc gctcggcccg ctgctggtcg
     9601 gcggcgttgc ggttgaccgc gcccgccagc agggccttga tctcgaccac cgcgtcgcgg
     9661 tcgtgggcga gcaggccggc ggtgaggtcc cggaccgcgt cggtcagctc ggcggtgggc
     9721 acgacgaggg tggccaggcc gatccggtcc gcctcggcgg cgtccatccg tcgaccggtc
     9781 gcgcagatct ccagggcccg ggagtagccg accaggtcga ccaggcgctt ggtgccggcg
     9841 aggtcgggga ccagcccgag ggtgacctcg gccatggcga gccgggcgtc ctcggcgagc
     9901 acccgcaggt cgcaggcgag ggcgagctgg aagccggcac cgatggcgtg cccctggacg
     9961 gcggcgaccg agacgatgtc gggccggtgc agccaggtga acgcggcctg gaactcggct
    10021 atccgctgcg cgcactcggc ctcgggcagg gtggccagct cggcgaacga gcccggcccg
    10081 gtggcaccgg cgactgccag gtcgaggccg gcggagaagg cccgcccctc gccgcgtacg
    10141 acgacgaccc ggacgtcacc gggcagctcc cgggagatgt cgacgagcgc gcgccacatc
    10201 gccggcgtct gggcgttgag cacgtcgggc cgacacaacg tcaccgtcgc gaccggcccg
    10261 gcgcagtcga tccgtacccc gtccgaaccg gcggtcaccg gcgaagcctg gggacggcgt
    10321 tgatgggcga gaccgggtgg gtcacgcctt cttgcgacgg cgggcaccgc cgcgctgacg
    10381 caactgcacg ccggactcgg tgagcacccg gtggatgaat ccgtacgaac ggccggtcga
    10441 ggccgcgagc gcacggatgc tctcccccga ggtgtaccgc tttaccaggt ccttggcgag
    10501 cgtctgacgc tcggctccga cgatccggcg acccttctca gtgctggtgg ctgtgccagt
    10561 ggctgccatg ctgattcctc acgtcccaga ctgtgcggtt cggatacggt caacacctat
    10621 tagaccgtct cgaacgatca tgcgccagat atcaactcat cgccaaccga cacgctctgc
    10681 attgtcagga acccgataga gtgacgccgc cggcccgacg ggaagcgcac gctgcggatt
    10741 cccaccggag gccggtctca tccgacgcga cgcaatgtcc aggaccggac accgaccgtc
    10801 agcgcaaggt cgcccg
//
