LOCUS       NZ_BMMJ01000001        14870 bp    DNA     linear   CON 09-SEP-2024
DEFINITION  Micromonospora yangpuensis strain CGMCC 4.5736 sequence01, whole
            genome shotgun sequence.
ACCESSION   NZ_BMMJ01000001
VERSION     NZ_BMMJ01000001.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Micromonospora yangpuensis
  ORGANISM  Micromonospora yangpuensis
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 1021831)
  AUTHORS   Sun,Q. and Zhou,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 133X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014645775.1-RS_2024_09_09
            Annotation Date                   :: 09/09/2024 04:34:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,914
            CDSs (total)                      :: 5,857
            Genes (coding)                    :: 5,698
            CDSs (with protein)               :: 5,698
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 20 of 159
            Pseudo Genes (incomplete)         :: 144 of 159
            Pseudo Genes (internal stop)      :: 5 of 159
            Pseudo Genes (multiple problems)  :: 9 of 159
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:15:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 584008
            Orig. end                         :: 598878
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMMJ01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..14870
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NAGGN"
                     /region_number="2"
                     /rules="((TIGR03104 or cds(GATase_7 and Asn_synthase)) and
                     TIGR03103 and (TIGR03106 or Peptidase_M42))"
                     /tool="antismash"
     cand_cluster    1..14870
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((TIGR03104 or cds(GATase_7 and
                     Asn_synthase)) and TIGR03103 and (TIGR03106 or
                     Peptidase_M42))"
                     /kind="single"
                     /product="NAGGN"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..14870
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:9870](+)"
                     /cutoff="10000"
                     /detection_rule="((TIGR03104 or cds(GATase_7 and
                     Asn_synthase)) and TIGR03103 and (TIGR03106 or
                     Peptidase_M42))"
                     /neighbourhood="5000"
                     /product="NAGGN"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..9870
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((TIGR03104 or cds(GATase_7 and
                     Asn_synthase)) and TIGR03103 and (TIGR03106 or
                     Peptidase_M42))"
                     /neighbourhood="5000"
                     /product="NAGGN"
                     /protocluster_number="1"
     gene            complement(13..681)
                     /locus_tag="IEY64_RS02555"
                     /old_locus_tag="GCM10012279_05200"
     CDS             complement(13..681)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY64_RS02555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10012279_05200"
                     /product="hypothetical protein"
                     /protein_id="WP_091434840.1"
                     /transl_table=11
                     /translation="MINPITDPAVLASRRNAKKLADLPLPADIVAAVPALVAALGDVDA
                     AEQAYRAAEDTYLDVDMIPAEHKAEVRAAIRAGKKPPTFDAITHEVQLEEAHIARKAAE
                     GRLREARIAYGLAIAEHADHLADLLAQQAMDAYAQLESALDAARAAFSRYGTVSNLRNS
                     LVPQAERAPWVGPNEVVYSGPVRLGRVVDAFEILTRAMDPTNLRPAAAREAVRTTGRLK
                     "
     gene            complement(871..1068)
                     /locus_tag="IEY64_RS02560"
                     /old_locus_tag="GCM10012279_05210"
     CDS             complement(871..1068)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY64_RS02560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10012279_05210"
                     /product="hypothetical protein"
                     /protein_id="WP_139135588.1"
                     /transl_table=11
                     /translation="MSKPLTAIHVSPERRHELLMASDFHCEANGCGHRAGYVAILPTGE
                     IGTACGRCATPPRAALGVAG"
     gene            complement(1201..1683)
                     /locus_tag="IEY64_RS02565"
                     /old_locus_tag="GCM10012279_05220"
     CDS             complement(1201..1683)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY64_RS02565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10012279_05220"
                     /product="hypothetical protein"
                     /protein_id="WP_139135587.1"
                     /transl_table=11
                     /translation="MDAYRYGDEMTPAARSAAWAIETWLTDLQTFRWLIGRFTSGPDLF
                     DAYMSTMDTLDYDADPVLLTGAPGGMFADTQMIGARVAVKRGPAVGEIMPAGRKTFATV
                     AREYLMSAVVHGKRGWMGVHLWRGAPIYTDRTRRERLIMRDRTYPRTGDRPLWERL"
     gene            complement(1829..1960)
                     /locus_tag="IEY64_RS30220"
                     /old_locus_tag="GCM10012279_05230"
     CDS             complement(1829..1960)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY64_RS30220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10012279_05230"
                     /product="hypothetical protein"
                     /protein_id="WP_268239621.1"
                     /transl_table=11
                     /translation="MTAPTITRRPTATRPRPLTDEATTAFRANVADYLAHRAARLSR"
     misc_feature    2473..2488
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     misc_feature    2559..2575
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.05"
                     /tool="antismash"
     misc_feature    complement(2570..2583)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.89"
                     /tool="antismash"
     misc_feature    2571..2584
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 18.03"
                     /tool="antismash"
     gene            complement(2883..4520)
                     /locus_tag="IEY64_RS02570"
                     /old_locus_tag="GCM10012279_05240"
     CDS             complement(2883..4520)
                     /GO_function="GO:0000150 - DNA strand exchange activity
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012464.5"
                     /locus_tag="IEY64_RS02570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_05240"
                     /product="recombinase family protein"
                     /protein_id="WP_091434837.1"
                     /transl_table=11
                     /translation="MITARPAAYVRQSSARANKSEASPATQRTATTERANHDHPGATVR
                     MFEDIDRSGYQVGVVREAYDQMVAAIKAGEITHLYVFYVSRLTRQDPRIALAEWLPLLA
                     GGLTIVSITEGTFGPDNTMDLIHLLLRMDAAHNESKNKSAAIKAAKALAHAAGGHLGNP
                     PFGFRTVERMAQTPAGEPVAIRALVIEPTEARALRVAVRAVLLGFAVHAVCRYFDRRGI
                     RTRGATVGRSRASGAWSDRNLHKRLRDPRIAGLPAVAILDDRDNITGYRTAYDLEDARV
                     LPPPAEPIITTEEFWRLQAILTGTARSIQSADEPALLSGLGILWCECGYRMKARRFVAN
                     ATLANRDAYMCTAPAGRHSNTISLTALDGWVRMRIDRLLNSIDPADEDQTTASILAEAT
                     RRYGAATATPETAVQRAAVSAELADATAALDQQSEALGTATGAAAAALTRAVTVTGARV
                     DALTARLAELDDQATAKLPLDLWTSSAYGDEPAWWDGATVGERRDFVTLFVDRITVRRA
                     ASKGGRPTKADPWGTVNARVTLDWAGTT"
     gene            <4550..4627
                     /locus_tag="IEY64_RS29445"
                     /pseudo=""
     CDS             <4550..4627
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007074691.1"
                     /locus_tag="IEY64_RS29445"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="peptide-methionine (S)-S-oxide reductase"
                     /pseudo=""
                     /transl_table=11
                     /translation="SKNPGGYCNHGPNGMTCPVGVARTA"
     misc_feature    complement(4830..4845)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.37"
                     /tool="antismash"
     gene            5001..6785
                     /locus_tag="IEY64_RS02575"
                     /old_locus_tag="GCM10012279_05250"
     CDS             5001..6785
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     TIGR03104"
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     GATase_7"
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007074689.1"
                     /locus_tag="IEY64_RS02575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_05250"
                     /product="N-acetylglutaminylglutamine amidotransferase"
                     /protein_id="WP_091434835.1"
                     /sec_met_domain="TIGR03104 (E-value: 6.8e-292, bitscore:
                     964.7, seeds: 10, tool: rule-based-clusters)"
                     /sec_met_domain="GATase_7 (E-value: 2.2e-41, bitscore:
                     136.5, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 2.9e-88, bitscore:
                     292.7, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGLAGELRRDGRAADVSAVARMAATMSDRGPDDGGLWAQGPVAF
                     GHRRLKIIDLSAASGQPIVDSAAGLTGVFNGCVYNYRELREELQAKGHRFFSTGDSEVV
                     LKAYAEWGLDFVDHLIGMFAVAITERATGRLVLARDRLGIKPLYVAETPGVVRFASTVP
                     ALLAGGDVDTDLDPVALAHYLSFHSVVPPPRTILRGVRKLPPATVRVYEPDGRVDERVY
                     WDPSFTRRADRADWSARDWEDALHESLTTAVRRRMVADVPVGVLLSGGLDSSLVVALLA
                     GEGQRGLATFSIGFDSVGGREGDEFRYSDVVAKTFDTDHHQIRVAAQDLLPPLEAAVAA
                     MAEPMVSHDCVAFYLLSQEVARHVKVVQSGQGADEILGGYHWYPPLASVGREQAVETYA
                     KAFFDRDAAGLARVLDPAWLADGDPAREFVAAHLARAGAETAVDAGLRLDTQVMLTDDP
                     VKRVDNMTMAHGLEARVPFLDHEFVELAATCPPELKLAQGGKGVLKEIGRRVLPHEVID
                     RPKGYFPVPGITHLEGKLLDRVRDALGAPEARRRNLFRPDYVNTLLDAPNAELTPLMGN
                     KLWQLGLLEMWLQSHGID"
     gene            6788..8689
                     /gene="ngg"
                     /locus_tag="IEY64_RS02580"
                     /old_locus_tag="GCM10012279_05260"
     CDS             6788..8689
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="ngg"
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     TIGR03103"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013731652.1"
                     /locus_tag="IEY64_RS02580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_05260"
                     /product="N-acetylglutaminylglutamine synthetase"
                     /protein_id="WP_091434833.1"
                     /sec_met_domain="TIGR03103 (E-value: 1.1e-204, bitscore:
                     676.7, seeds: 7, tool: rule-based-clusters)"
                     /sec_met_domain="RimK (E-value: 6.8e-07, bitscore: 24.9,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTLATGVARTDRSRGRGSRYERVGPGGDPMAPTAADDAVRRSG
                     DDTGVVLDCGWGRLVFGQTFSEQAAVADVLRSEAAGARDICVYLRDPHVLVSRLPDEIF
                     IDPSLTYRLPLGPGRFTGTAGPTTDDGIGDTPRAAAGTGATVEHGDVPGLRIRQLRDAA
                     DADAVNRIYARNSMVTAPVDVLVANAGTDKFLHLVAEAVTGEIVGTITGVDHTAVFDDP
                     ENGASLWCLTVDFNQAPPGTGQALLLELAARLTDRGRAFVDLSVLAENEGAIRLYERLG
                     FYRIATLCVKRKNPINERLFLPGVPVGYDELNPYARIVADEAMRRGIRVEVTDPHWGEL
                     RLSNGGRTVLTRESLSELTTAVAMSRCDDKRVTRRILTAAGLSVPRGRTATRDEADAAF
                     LAELGEVVVKPARGEQGNGITVGVRTPEALVTAVALASQFCPDVLIEELRAGEDLRVIV
                     INHEVVAAAVRRPASITGDGVHPVGKLIERQSRRRAAATGGESRIPIDDLTREVVAEAG
                     YAMDDVLPEGEVLAVRRTANLHTGGTMHDVTGELHPKIAEACVAASRALDIPVTGLDLL
                     VPAPDRPEHVFIEANERPGLANHEPQPTAERFVDLLFPGTRAPQRLWTPAGAAPSGT"
     gene            8686..9870
                     /locus_tag="IEY64_RS02585"
                     /old_locus_tag="GCM10012279_05270"
     CDS             8686..9870
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     Peptidase_M42"
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     TIGR03106"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018787511.1"
                     /locus_tag="IEY64_RS02585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_05270"
                     /product="osmoprotectant NAGGN system M42 family peptidase"
                     /protein_id="WP_091445983.1"
                     /sec_met_domain="TIGR03106 (E-value: 1.5e-144, bitscore:
                     476.8, seeds: 7, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_M42 (E-value: 2.5e-54, bitscore:
                     180.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTARTIAPLKLDLDYLQQVMLELLDIPSPSGRTDHVQQYVGERLS
                     ALGISSTLTRRGALSACLAGPRQTGADRAIVVHTDTIGGMVKRLKENGRLELKPIGTHS
                     ARFAEGAHVRIFTDELDQVITGQVLPLKASGHRYNDDVDLQGVGWEHVEVRVDEPVEGI
                     AGLRALGIDAGDFVAIIPTATITPSGYVKSRHLDDKAGVAAVLTAFKAIVDAGITPAVT
                     AHLLVTVTEEIGHGASHGLDPDVAEIISVDAAVVAPGQQSRETSATLAMGDGVGPFDYH
                     LTRKLAGIAAEHGVDLVRDVFDYYRSDVAAAVEAGAHARVALLGFGVDATHGHERTHLE
                     GLRHLTQLLCLYLQSDLVFPEWDAEPEGELADFPSLSVQPASEEGPREGPIGLD"
     misc_feature    complement(10157..10172)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.95"
                     /tool="antismash"
     gene            10391..11305
                     /locus_tag="IEY64_RS02590"
                     /old_locus_tag="GCM10012279_05280"
     CDS             10391..11305
                     /EC_number="3.1.26.11"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018586560.1"
                     /locus_tag="IEY64_RS02590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_05280"
                     /product="ribonuclease Z"
                     /protein_id="WP_091434831.1"
                     /transl_table=11
                     /translation="MSTRELVVLGTASQTPTRQRNHNGYVLRWDDEVILFDPGEGSQRQ
                     LLHTGVTATQLTRICVTHFHGDHCLGLPGLIQRLSLDRVPHPVPVHFPAGGVDYFARLR
                     HASSFHETAELRPEPVDTDGARFALTGATLQARRLRHPIETYGYRLVEPDGVRMLPERL
                     AAYGIVGPAVGELQRAGYLEVGGRRVTLAEVSRPRPGQRFAFVMDTGLCDGVYALAERA
                     DLLVIESTFLNSEAALAAEVGHLTAAQAARVATESGVRRLVLTHFSQRYADPERFAAEA
                     REHFAGELVIAEDLSVVPVPPRR"
     gene            11315..11824
                     /locus_tag="IEY64_RS02595"
                     /old_locus_tag="GCM10012279_05290"
     CDS             11315..11824
                     /EC_number="2.3.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007455719.1"
                     /locus_tag="IEY64_RS02595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_05290"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_091434829.1"
                     /transl_table=11
                     /translation="MTLTLRHATLDDLHPVGALHHRSRVATYSAFLPVEALAEPSAQAM
                     GAYWAERWVWERDDHLMTVAERDGQLVGFSYLGPDDGGDPATGLLNALHLDPAERGRGT
                     GRLLMVDALAVMRDRAWRRATLWVLERNTLARRFYERGDWRPTGERRTDRIGTIPTTQL
                     RYHRPV"
     gene            complement(11888..12850)
                     /locus_tag="IEY64_RS02600"
                     /old_locus_tag="GCM10012279_05300"
     CDS             complement(11888..12850)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012976.5"
                     /locus_tag="IEY64_RS02600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_05300"
                     /product="protocatechuate dioxygenase"
                     /protein_id="WP_091434826.1"
                     /transl_table=11
                     /translation="MEHAHDHHEGQRVSRRRLIAGIGSVGLAGLLTACGRDGGTVTTST
                     GETVTPQASTTSDLTGLFADANTCTLTASTTQGPYYFDADKIRSDIREDRAGTRLRLAI
                     RVQDSEACGPLPNAVVEIWHCDAAGLYSGAEAQSSGADDGPGGAAGGPGDAGTPPSGGP
                     GDAGTPPSGGPGDAGAPPSGAAGGAPGSGGPRGDGGGAADLTPTDDQRYLRGAQVTNAD
                     GIVEFTTIWPGWYRGRTVHVHAMVHVDNSRVLTTQVMFDEALNTKVFAAQPYAAHSGRD
                     TFNDNDSIYADSMLLTLSEEGDGFLGVINFSVDSDQDGS"
     gene            complement(13042..14412)
                     /locus_tag="IEY64_RS02605"
                     /old_locus_tag="GCM10012279_05310"
     CDS             complement(13042..14412)
                     /EC_number="4.2.1.22"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004122 - cystathionine beta-synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019343 - cysteine biosynthetic process via
                     cystathionine [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007455717.1"
                     /locus_tag="IEY64_RS02605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_05310"
                     /product="cystathionine beta-synthase"
                     /protein_id="WP_091434824.1"
                     /sec_met_domain="PALP (E-value: 3.1e-71, bitscore: 236.0,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRYYDNVVDMIGDTPLVRLRNVTEGIRATVLAKVEYLNPGGSVKD
                     RIALRMVEDAEAAGILKPGGTIVEPTSGNTGVGLALVAQLKGYHCVFVCPDKVSQDKQD
                     VLRAYGAEVVVCPTAVAPEDPRSYYNVSDRLAREIPGAWKPDQYSNPANPRSHYETTGP
                     ELWQQTEGRITHFVTGVGTGGTISGIGRYLKEVSDGRVRVVGADPEGSVYSGGTGRPYL
                     VEGVGEDFWPETYDRSVADEIVEVSDKASFEMTRRLAREEGLLVGGSCGMAVVAALEIA
                     RQAGPDDVVVVLLPDSGKGYLSKIFNDAWMARYGFLTASGTEPTVADALSSKPGGLPEL
                     VHVHPTETVRDAIDYMREYGVSQLPVLKAEPPVVTGEVAGSIAEKDLLDALFTGQAHLH
                     DTIERHMADPLPMIGGGQPVSEAVGLLEKSDAALVLVDGKPKGVLTRQDLLAHLGAH"
     gene            complement(14486..14842)
                     /locus_tag="IEY64_RS02610"
                     /old_locus_tag="GCM10012279_05320"
     CDS             complement(14486..14842)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007074683.1"
                     /locus_tag="IEY64_RS02610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_05320"
                     /product="YkvA family protein"
                     /protein_id="WP_091434822.1"
                     /transl_table=11
                     /translation="MGRTLKRTAAFTALARALAAGSRGGPALGTRVAAVPRMIRASMRG
                     EYDGGLRLALMTAAVAYVASPVDLVPELMLSVFGLVDDAVVVTWLAGTVLAETERFLQW
                     EKTRSPVVPGHVVP"
ORIGIN
        1 cgtatcgctg ggtcacttga gccgtcccgt cgtgcgcact gcttcgcggg cagcggccgg
       61 tcgcaggttg gtcgggtcca tcgcgcgggt cagaatctcg aacgcatcga ccacccgtcc
      121 gaggcggacc gggccggaat agacaacctc gttcgggcct acccacggcg cacgctcggc
      181 ctgcgggaca agcgagttac gcaggttcga caccgtgccg taccgggaga acgccgcgcg
      241 ggcagcgtcc aacgcggact caagctgcgc gtaggcgtcc atcgcctgct gcgccagcag
      301 gtcggccagg tggtcggcgt gctcagcgat ggcgaggccg tacgcgatgc gggcttcgcg
      361 caggcggcct tcggcggcct tcctggcgat gtgcgcctcc tcaagctgca cctcgtgcgt
      421 gatcgcgtcg aacgtcggcg gcttcttacc ggcccggatc gcggcccgca cctcagcctt
      481 gtgctcggcc gggatcatgt ccacgtcgag gtaggtgtct tcggcagccc ggtaagcctg
      541 ctcggcggca tccacatcgc ccagcgcggc gaccagggcc ggcacggcgg ccacgatgtc
      601 ggccggcagc ggcagatcgg caagcttctt cgcgttgcgg cgcgaggcga gaacggcggg
      661 atcggtgatg gggttgatca ctgtgactcc agtggttgac cgcgtgtcat ccaacaggcg
      721 gtgtaagggg atgccgggga aaccgcccgg cgcgggggta tgggggcgct gctcccccgg
      781 tcgctttcag gagtagcgac cgggggcgcg ccatgtccgc gcgctacctt cctcaagagc
      841 gcgcggggtc tatcagcggc ggccggggtg ctagccggcg acgcccaggg cggcacgcgg
      901 cggggtggcg caccgtccgc aggcggtgcc gatctcgccg gtcggcagga tcgctacgta
      961 cccggcccgg tgcccgcatc cgttggcctc acagtggaag tcggatgcca tcagcagctc
     1021 gtgccggcgc tcgggcgaga catggatagc ggtcagcggt ttagacatcg gggggactcc
     1081 aagcgatgtt gagcggcggt caccgggggg ccgtccaggt ctgcggcgtc gagcggccga
     1141 gcggcgacgg tgccaggcac gcggcggcca ggcgggcgag cgtgtgcatg agccggcgca
     1201 tcacagccgc tcccacagcg gacgatcacc ggtgcgcggg tacgtgcggt cgcgcatgat
     1261 caggcgttcg cggcgggtgc ggtccgtgta gatcggggca ccccgccaga gatgcacacc
     1321 catccagccg cgcttgccgt ggacaacggc gctcatcagg tactcgcggg ccacggtggc
     1381 gaacgtcttg cggccggcgg gcatgatctc gccaacggcc gggccgcgct tgacggccac
     1441 gcgagcgccg atcatctgcg tgtcggcgaa catgccaccg ggggcaccgg tcaacagcac
     1501 cgggtcggcg tcgtagtcga gggtgtccat agtcgacatg taggcgtcga acaggtccgg
     1561 gcctgacgtg aaccggccga tcagccagcg gaacgtttgc aggtcggtca gccaggtttc
     1621 gatggcccag gctgcggagc gggcggcggg ggtcatctca tcgccgtatc ggtatgcgtc
     1681 cacggggtca cctccaatcg gttgcagggc aacgaaaaac gccccggcgg ctgtgagaga
     1741 tgcgacctct cacagcgccg gggcgctggt ctttcggtgt tgctgtccgc gccgtgtgtg
     1801 tcgcatacac gcggtgcggg gtgctgccct accgggacag gcgggcggcg cggtgcgcca
     1861 ggtagtcggc cacgttcgcg cggaacgcgg tggtggcctc gtcagtcagt ggccggggcc
     1921 gggtcgcggt ggggcggcgg gtgatcgtcg gggcagtcat ggttcctcca ctctgggcag
     1981 tggcagacgg cgaaaccgcc cggacatggg tgggccgatc tcctgacggc aaccaagatc
     2041 ggctcactca tgaccgggcg gggtcggggg gcgcgacggg ttgccggtcg tcgcggtgcg
     2101 cggggtccgc ccgtctcggg cggtggtcgt acgggggctc actatgtatg tcccccaagg
     2161 ggggaaacgc gggggccggg gggctgtggg gggtcactga atatgtccca cagcggtaaa
     2221 acgccctggt cgcaggcttg cgacgggggg ccgactttcg gcggcgggtg ggctctgcct
     2281 gctcccaccc ggtacgtcct acagcggtaa atctctgtac taggtaagtc ctcagcgttg
     2341 taagggcatg ggcgcagccg ggcggcccga ctgccggcgg cgcgcccgtg ggttacgggg
     2401 gccggacgcg ggcgcagccg gggctgccca agaattaccc cccggatggc gcaccccggg
     2461 ccggtaagtg tcgtcacccc gttgtcactt acccccctga taacgcaccc atcctcgggc
     2521 gcaggcgcag cgggggatgc ccagggacta cagagggcac ttaagttaac tacagttatt
     2581 atagtagagg gttataagag gatgaaatag gacagattga gagagaagga aaacgggcgg
     2641 cgaggcgaca agagtccgaa cgccattacc ccccgaatgg cgcacccacg tcgtcacccc
     2701 tcggcggcgc taccgaccag cggggcaggg ctgcggcggg atggcatcgg aaacgggctg
     2761 tacgccacgc tgtcggccgt gcggactgtc cgggtgctta cccggacgtc ggacgcacag
     2821 cggcccgcta cggggcacgt agcgggcact tgttgacgct gggcgggaca ggggcgtgcg
     2881 acctatgtag tgccggccca atccagcgtt acgcgggcgt tcacggtgcc ccacgggtcg
     2941 gccttggtcg ggcggccacc cttggatgcc gcacggcgaa ccgtgatccg gtcaacgaac
     3001 agggtcacga agtcgcgccg ctcccccacc gtggcaccgt cccaccacgc cggctcgtcg
     3061 ccgtaggcgc tggatgtcca gaggtccagc ggcagcttgg cggtggcctg gtcgtccagc
     3121 tcggccaggc gggcggtaag ggcatcgacg cgggcaccgg tcaccgtgac ggcgcgggta
     3181 agcgctgcgg cggcggcacc cgtggcggtc cccagggcct cggattgctg gtcgagggct
     3241 gcggttgcgt cggccagctc ggcggacact gcggcgcgct gcacggcggt ctccggcgtt
     3301 gccgtcgctg cgccgtagcg gcgggtcgcc tcggccagga tcgaggcggt ggtctggtcc
     3361 tcgtcggccg gatcgatcga gttgagcagg cggtcgattc gcatgcggac ccatccatcg
     3421 agcgcggtca ggctgatggt gttggaatgc cggcccgccg gggcggtgca catgtaggcg
     3481 tcgcgattcg ccagggtggc gtttgcgacg aaccgacgcg ccttcatccg gtacccgcac
     3541 tcgcaccaca ggatgcccag accggagagt agggccggct cgtcggcgga ctggatcgac
     3601 cgggcggtgc cggtgaggat ggcttgcaga cgccagaact cctcggtggt gatgatcggc
     3661 tcggccggcg gcggcaacac gcgggcgtct tccaggtcgt acgcggtgcg gtagccggtg
     3721 atgttgtccc ggtcatcgag gatggcgacg gccggcaggc cagcgatgcg ggggtcacgc
     3781 agccgcttgt gtaggttccg gtccgaccag gcacccgacg cgcgagagcg gcccaccgtc
     3841 gcgccgcgcg tgcggatgcc ccggcggtcg aagtagcggc acacggcgtg cacagcgaag
     3901 ccgagcagca cggcgcgcac ggccacccgt agcgcgcggg cctcggtcgg ctcgatgacc
     3961 agggcgcgga tggcgaccgg ctcgcctgcg ggggtctgcg ccatgcgctc gacggtgcgg
     4021 aatccgaacg gcgggtttcc gaggtgtccc ccggcggcgt gcgcaagggc ctttgcggct
     4081 ttgattgcgg cggacttgtt ctttgactcg ttgtgggcag cgtccattcg cagcaggagg
     4141 tggatcagat ccatcgtgtt atccgggccg aatgtgcctt cggtgatgct gacaatggtc
     4201 aggccaccgg cgagcagcgg cagccattcg gcaagggcga tacgcggatc ttggcgggtg
     4261 aggcgggaga cgtagaagac atagaggtgc gtgatttcgc cggccttgat cgccgctacc
     4321 atctggtcgt acgcctcacg aaccacgccg acctgatagc cggatcggtc gatgtcctcg
     4381 aacatgcgga cggttgcgcc ggggtggtcg tggttggcgc gctcggtggt ggcggtgcgc
     4441 tgcgttgccg gggacgcctc ggacttgttc gcgcgggcgg acgactgccg cacgtaggcg
     4501 gcggggcgag cggtgatcat ggctccacag tagtcatggt ccgtcaggtt ccaagaatcc
     4561 gggaggttac tgcaaccacg gcccgaacgg gatgacctgc ccggtgggcg tggccaggac
     4621 ggcctgaccc cggcagggcg ctggcgcgga tcgcggagcc cgccggagcc caccggatcg
     4681 cggagcccac cgatcacgga gcccgccgga tcgcggagcc caccgatcgc gaccgggacg
     4741 tcgacactca ccgcaggtga aacgtggcgg aaagcgactg ccgaccctgc cgcgcgggcg
     4801 aatcgcccgc gcggcagggt cggcagtttt gtggtcaaca ccacaccgct gatgcggcaa
     4861 aacaggatga acgtccccgc gcttttcgga cttttccgca gtatgcaccc tacccaaagc
     4921 ccgcaaccgt atcagcctgt tgcaccatcg cccactagcc gaacgggcaa ttctccggca
     4981 ttcctggcac cattgaccgc atgtgcggac tggcagggga gctccggcgg gacggtcgcg
     5041 ccgccgacgt gtcggcggtg gcccgcatgg cggcgacgat gagtgaccgg gggccggacg
     5101 acggcgggct gtgggcgcag gggccggtgg cgttcggtca ccgacgactg aagatcatcg
     5161 acctctccgc cgccagtggt caacccatcg tcgactccgc cgccggactc accggcgtct
     5221 tcaacggctg cgtctacaac taccgcgagc tgcgcgagga gctgcaggcc aagggccacc
     5281 gcttcttctc caccggggac agcgaggtgg tgctcaaggc gtacgccgag tggggtctgg
     5341 acttcgtcga ccacctgatc ggcatgttcg ccgtggcgat caccgaacgg gccaccggcc
     5401 ggctggtgct ggcccgcgac cggctcggca tcaagccgct ctacgtcgcc gagacgccgg
     5461 gcgtggtgcg cttcgccagc acggtccccg ccctgctcgc cggcggcgac gtcgacaccg
     5521 acctcgaccc ggtggcgctc gcccactacc tcagcttcca cagcgtcgtc ccgccgccgc
     5581 ggaccatcct gcgcggcgta cgcaagctcc cgccggccac cgtccgggtc tacgagcccg
     5641 acgggcgggt cgacgagcgg gtctactggg acccgtcctt cacccgccgg gccgaccggg
     5701 ccgactggtc ggcccgggac tgggaggacg ccctgcacga gtcgctgacc accgcggtac
     5761 gccgccggat ggtcgccgac gtgccggtcg gcgtgctgct ctccggtggc ctggactcca
     5821 gcctggtggt ggcgctgctg gccggtgagg gccagcgcgg cctggccacc ttctcgatcg
     5881 gcttcgactc ggtgggcggt cgggagggcg acgagttccg ctactccgac gtggtcgcca
     5941 agaccttcga caccgaccac caccagatcc gggtcgccgc ccaggacctc ctgcccccgc
     6001 tggaggcggc ggtcgcggcg atggccgagc cgatggtcag ccacgactgt gtggcgttct
     6061 acctgctcag ccaggaggtc gcccggcacg tcaaggtggt ccagtccggt cagggcgcgg
     6121 acgagatcct cggcggctac cactggtacc cgccgctggc ctcggtcggc cgggagcagg
     6181 cggtcgagac gtacgcgaag gccttcttcg accgggacgc ggccgggctg gcccgggtgc
     6241 tcgacccggc ctggctggcc gacggcgatc cggcgcgcga attcgtcgcg gcgcacctgg
     6301 cccgcgccgg tgccgagacc gcggtcgacg ccggtctgcg cctggacacc caggtcatgc
     6361 tcaccgacga cccggtcaag cgggtggaca acatgacgat ggcgcacggg ctggaggccc
     6421 gggtgccctt cctcgaccac gagttcgtcg agctggccgc tacctgcccg cccgagctga
     6481 agctggccca gggcggcaag ggcgtgctca aggagatcgg gcggcgggtc ctgccgcacg
     6541 aggtgatcga ccggcccaag ggctacttcc cggtgcccgg catcacccac ctggagggca
     6601 agctgctcga ccgggtacgt gacgcgctgg gtgccccgga ggcccgccgc cgcaacctgt
     6661 tccgtcccga ctacgtcaac accctgctcg acgccccgaa cgccgaactc accccgttga
     6721 tgggaaacaa gctgtggcag ctcggactcc tcgagatgtg gctgcagagc cacggaatcg
     6781 actgaccgtg accgacaccc tggccaccgg agtggcgcgt accgaccggt cccgtgggcg
     6841 cggtagccgc tacgagcggg tcgggccggg cggcgacccg atggccccca ccgccgcgga
     6901 cgacgccgtc cgccggtcgg gcgacgacac cggtgtggtc ctcgactgcg gctggggccg
     6961 gttggtcttc gggcagacct tcagtgagca ggccgccgtg gccgacgtgt tgcgttcgga
     7021 ggccgccggt gcccgggaca tctgcgtcta cctgcgcgac ccgcacgtgc tggtgtcccg
     7081 actgccggac gagatcttca tcgacccgtc cctgacgtac cggctgccgc tcggtcccgg
     7141 ccgcttcacc gggacggccg ggccgaccac cgacgacggc atcggcgaca ccccgcgggc
     7201 cgctgccggt accggggcga cagtcgagca cggtgacgtc ccgggactgc ggatccgtca
     7261 gctgcgggac gccgccgacg cggacgcggt gaaccggatc tacgcccgca acagcatggt
     7321 caccgccccg gtcgacgtgc tggtggccaa cgccggcacg gacaagttcc tgcacctggt
     7381 cgccgaggcg gtcaccggcg agatcgtcgg caccatcacc ggcgtggacc acacggcggt
     7441 cttcgacgac cccgagaacg gtgccagcct ctggtgtctg accgtggact tcaaccaggc
     7501 ccctccgggc accggccagg cgctgctgct ggagctggcg gcccggctga ccgaccgggg
     7561 gcgggccttc gtcgacctgt cggtgctcgc cgagaacgag ggggcgatcc ggctctacga
     7621 gcggctcggc ttctaccgca tcgcgacgct ctgcgtgaag cggaagaacc cgatcaacga
     7681 gcggctcttc ctgcccggcg tgccggtggg ctacgacgag ttgaatccgt acgccaggat
     7741 cgtcgccgac gaggcgatgc gccgcggcat ccgggtggag gtcaccgacc cgcactgggg
     7801 tgagctgcgg ctgagcaacg gcggacggac ggtgctcacc cgggagtcgc tgtcggagtt
     7861 gaccacggcg gtggcgatga gccgctgcga cgacaagcgg gtcacccgcc ggatcctcac
     7921 cgcggccggc ctctcggtcc cccggggccg caccgcgacc cgggacgagg ccgatgcggc
     7981 cttcctcgcc gagctgggtg aggtggtggt caagccggcc cgcggtgagc agggcaacgg
     8041 catcaccgtc ggggtacgca ccccggaggc gctggtcacc gccgtcgcgt tggcctccca
     8101 gttctgcccg gacgtgttga tcgaggagct gcgcgccggc gaggacctgc gggtgatcgt
     8161 gatcaaccac gaggtggtgg ccgccgcggt gcgccggccc gcgtcgatca ccggtgacgg
     8221 ggtgcacccc gtcggcaaac tgatcgagcg gcagagccgt cgccgggccg ccgccaccgg
     8281 cggtgagtcc cggatcccga tcgacgacct gacccgggag gtggtggccg aggccgggta
     8341 cgcgatggac gacgtgctgc ccgaggggga ggtgctcgcc gtccgtcgga ccgccaacct
     8401 gcacaccggc ggcacgatgc acgacgtcac aggtgagctg cacccgaaga tcgccgaggc
     8461 gtgtgtggcc gccagccggg cgttggacat cccggtcacc gggctggacc tgctggtgcc
     8521 cgcccccgac cggcccgaac acgtgttcat cgaggccaac gagcggcccg gcctggccaa
     8581 ccacgagccc caaccgaccg ccgaacgctt cgtcgacctg ctgttccccg gaacacgggc
     8641 accgcaacgg ctgtggactc cggcgggtgc ggcaccatct gggacatgac cgcacgcacc
     8701 atcgctccgc tcaaactcga tcttgactac ctccagcagg tgatgttgga actgttggac
     8761 atcccgagtc cgtcggggcg taccgaccac gtgcagcagt acgtgggtga gcgcctctcg
     8821 gcactcggca tctcgtccac gctgacccgc cggggcgcgc tcagcgcgtg cctggccggc
     8881 cctcggcaga ccggggccga ccgggcgatc gtggtgcaca ccgacaccat cggcgggatg
     8941 gtgaagcggc tgaaggagaa cggccggctg gaactcaagc cgatcggcac ccacagcgcg
     9001 cggttcgctg agggcgccca cgtccggatc ttcaccgacg aactggacca ggtcatcacc
     9061 ggtcaggtac tgccgttgaa ggccagcggg caccgctaca acgacgacgt ggacctgcag
     9121 ggcgtcggtt gggagcacgt cgaggtccgg gtggacgagc cggtcgaggg catcgccggc
     9181 ctgcgggcgc tcggcatcga cgccggggac ttcgtggcca tcatcccgac ggccacgatc
     9241 acccccagcg ggtacgtcaa gtcccggcac ctggacgaca aggccggggt ggccgcggtg
     9301 ctgaccgcgt tcaaggcgat cgtcgacgcc gggatcacgc cggcggtcac cgcccacctg
     9361 ctggtcacgg tcaccgagga gatcgggcac ggggccagtc acggcctcga cccggacgtg
     9421 gccgagatca tctcggtgga cgcggccgtg gtagctcccg gacagcagtc ccgggagacc
     9481 tcagccaccc tggccatggg cgacggggtg ggaccgttcg actaccacct gacccgcaaa
     9541 ctcgccggca tcgccgccga gcacggggtc gacctggtcc gggacgtctt cgactactac
     9601 cgctcggacg tggcggcggc cgtcgaggcg ggggcgcacg cccgggtggc gttgctcggt
     9661 ttcggcgtgg acgccaccca cgggcacgag cgcacccacc tggaggggct gcgccacctg
     9721 acccaactgc tctgcctcta cctgcagagc gacctggtct tcccggagtg ggacgccgag
     9781 cccgaggggg agctggccga cttcccgtcc ctgtcggtgc agccggccag cgaggagggc
     9841 ccccgcgagg gccccatcgg cctcgactga ggtgtaagga agggcccccg cttaacgcat
     9901 aacgtcgaga gggtgcccct tctcaccaac catctggccg tcgagccgct cggcctcgcg
     9961 cagcggggcg gtgcggcgca gtcgccgatg tcccgcttgc gcagcggtcc gtggtcggtg
    10021 accggtttcc cgccaccgca cgaggcgccg gacacctccc gacgccgtga tccgccgcac
    10081 caggagagaa gaactccgaa aaaggagtac cggacccggc cgacgactgg gtagcgtggc
    10141 ggtacacggg aaaggaggtg gtccagactt gtatagcaat cggactcgtg aggtggctgt
    10201 ccgctagccg ctgtcctcga cagtgaaaac tcgtccgtcg cgaggcggac acgcaagatc
    10261 gtcgagaccg tgtggcagcg gtgcggcgaa accacgacag ccacccgacc cccggggtgc
    10321 cggcccaagt ccagccggcc cgcgcgcgag cgcggaagcc ccgggggtcg cttcatgtcc
    10381 gggagggccc ttgtccacgc gggaactggt ggtgctcggg acggccagcc agacgccgac
    10441 ccggcagcgc aaccacaacg ggtacgtgct gcgctgggac gacgaggtga tcctcttcga
    10501 cccgggcgag ggcagccagc ggcaactgct gcacaccggc gtcaccgcca cccaactgac
    10561 ccggatctgc gtcacccact tccacggcga ccactgcctc ggcctgcccg gcctgatcca
    10621 acggctcagc ctggaccggg tcccgcaccc ggtgccggtg cacttccccg ccggcggcgt
    10681 cgactacttc gcccggctac ggcacgccag ctccttccac gagaccgccg aactgcgccc
    10741 cgagccggtc gacaccgacg gcgcgcggtt cgccctgacc ggagcgacgc tccaggcccg
    10801 ccgactgcga cacccgatcg agacctacgg gtaccggctg gtcgaaccgg acggcgtccg
    10861 gatgctgccc gagcggctgg ccgcgtacgg catcgtcggg ccggcggtcg gcgagctgca
    10921 gcgcgccggt tacctggagg tcggcgggcg tcgcgtcacc ctggccgagg tgagccggcc
    10981 ccgacccggg cagcggttcg ccttcgtgat ggacaccggc ctctgcgacg gggtgtacgc
    11041 cctcgccgag cgggccgacc tgctggtcat cgagtcgacc ttcctcaact cggaggccgc
    11101 cctcgccgcc gaggtcggcc acctgaccgc ggcgcaggcc gcccgggtgg ccaccgagtc
    11161 cggggtacgc cgactcgtgc tcacccactt ctcccagcgg tacgccgacc cggaacgctt
    11221 cgccgccgag gcgcgggagc acttcgccgg ggagctggtg atcgccgagg acctgagcgt
    11281 cgtgccggtg ccaccccggc ggtagcctcg gacggtgacg ctcaccctcc gccacgccac
    11341 cctcgacgat ctgcacccgg tcggtgccct gcaccaccgc tcccgggtcg ccacctactc
    11401 ggcgttcctg ccggtggagg cgctggccga gccgtccgcg caggcgatgg gggcgtactg
    11461 ggccgaacgc tgggtctggg agcgcgacga ccacctgatg accgtcgccg agcgcgacgg
    11521 ccagctggtg ggcttcagct acctgggccc ggacgacggt ggcgacccgg ccaccggcct
    11581 gctcaacgcc ctgcacctcg accccgccga gcgggggcgg ggcaccggcc ggttgttgat
    11641 ggtcgacgcg ctggcggtga tgcgggaccg ggcctggcgg cgggccaccc tctgggtgct
    11701 ggaacgcaac accctggccc gccggttcta cgaacggggc gactggcggc ccaccggtga
    11761 gcgccgtacg gaccggatcg gcaccatccc caccacccaa ctccgctacc accgccccgt
    11821 gtaaggaagg gccccctgtt aacgctttag gtagagaggg gcaccccgct caccatccgg
    11881 atgcgggtca ggagccgtcc tggtcggagt cgaccgagaa gttgatcact ccgaggaagc
    11941 cgtctccctc ctcgctcagc gtcaacagca tgctgtcggc gtagatgctg tcgttgtcgt
    12001 tgaaggtgtc ccggccgctg tgcgcggcgt acggctgggc ggcgaagacc ttcgtgttga
    12061 gcgcctcgtc gaacatgacc tgggtggtga gcacccgact gttgtccacg tgcaccatgg
    12121 cgtgcacgtg gacggtgcgt ccccggtacc aaccaggcca gatggtggtg aactcgacga
    12181 tcccatcggc gttggtgacc tgcgccccgc gcaggtaccg ctgatcgtcg gtcggggtga
    12241 ggtctgcggc cccgcccccg tcgcccctgg gtccgccact gcccggggca ccgcccgcgg
    12301 caccgctggg cggcgcacca gcgtcacccg gaccaccgct cggcggcgta ccagcgtcgc
    12361 ctggaccgcc gctcggtggc gtaccagcat cacccggacc accggcagcg ccgccgggcc
    12421 cgtcgtccgc gcccgaggac tgcgcctcag cgcccgagta gagcccggcg gcgtcgcagt
    12481 gccagatctc caccaccgcg ttcggcaggg gcccgcacgc ctcgctgtcc tgcacccgga
    12541 tggccaaccg caaccgggta ccggcccggt cctcccggat gtcgctacgg atcttgtcgg
    12601 cgtcgaagta gtacgggccc tgggtggtgc tcgcggtgag cgtgcaggtg ttcgcatcgg
    12661 cgaacaagcc ggtcaggtcg ctcgtggtgc tggcctgcgg ggtgacggtc tcgccggtcg
    12721 acgtggtgac ggtgcccccg tcccggccgc aggcggtcag caggccggcc aggccgaccg
    12781 agccgatccc ggcgatcagc cgacgccggc tgacccgttg cccctcgtgg tggtcgtggg
    12841 cgtgttccat gcggtcctcc caggtccgtg gtggatcagg tgatccacca cggacgttag
    12901 ggagaccggt tacgcgggcg ctgtgcggcg ggtgtgccgg cgctgtggat ccggccagcc
    12961 tcgggtcccc acccgcgtac ggtaagaagg gagcccttct ataccgcagg cgttaacagg
    13021 gggcccttcc ttacacgcgg gtcagtgggc gccgaggtgg gccagcaggt cctgtcgggt
    13081 gagtacaccc ttgggcttgc cgtcgaccag gaccagcgcg gcgtcggact tctccagcag
    13141 gcccaccgcc tcgctcaccg gctgcccgcc accgatcatc ggcagtgggt cggccatgtg
    13201 ccgctcgatc gtgtcgtgca ggtgcgcctg accggtgaag agggcgtcga gcaggtcctt
    13261 ctcggcgatc gagccggcca cctcgccggt gaccaccggc ggctcggcct tgagcaccgg
    13321 aagctgggag acgccgtact cgcgcatgta gtcgatggcg tcgcggaccg tctcggtcgg
    13381 gtgcacgtgg accagctcgg gcaggccacc cggcttgctg gacagggcgt ccgcgacggt
    13441 cggctcggtg ccggaggcgg tcaggaagcc gtaccgggcc atccaggcgt cgttgaagat
    13501 cttggacagg tagcccttgc cgctgtccgg cagcaggacc acgaccacgt cgtccgggcc
    13561 ggcctgccgg gcgatctcca gcgcggccac gacggccatc ccgcaggagc cgccgaccag
    13621 cagcccctcc tcgcgggcca gccgccgggt catctcgaac gaggccttgt ccgacacctc
    13681 gacgatctcg tcggcgacgg agcggtcgta ggtctccggc cagaagtcct caccgacccc
    13741 ctcgaccagg tacggccggc cggtcccgcc cgagtagacc gagccctccg ggtcggcacc
    13801 gaccacccgg acccgcccgt cggagacctc cttgaggtac cggccgatgc cggagatggt
    13861 gccgccggtg cccaccccgg tgacgaagtg ggtgatccgg ccctcggtct gctgccacag
    13921 ctcgggaccg gtggtctcgt agtgcgagcg cgggttggcc gggttgctgt actggtcggg
    13981 cttccaggcg ccggggatct cccgggccag ccggtcggag acgttgtagt aggagcgcgg
    14041 gtcctccggg gcgaccgcgg tggggcagac caccacctcg gcgccgtacg cccgcagcac
    14101 gtcctgcttg tcctggctga ccttgtccgg gcagacgaag acgcagtggt agcccttgag
    14161 ctgagccacc agggccagtc cgacgccggt gttgccgctg gtcggctcga cgatggtgcc
    14221 gccgggcttg aggatcccgg cggcctcggc gtcctcgacc atccgcagcg cgatgcggtc
    14281 cttcaccgaa ccgccggggt tgaggtactc gaccttggcc agcacggtcg cccggatgcc
    14341 ctcggtgacg ttgcgcagcc gcaccagcgg ggtgtcgccg atcatgtcga cgacgttgtc
    14401 gtagtaccgc acctcgttgt gcccctcact ccggccccgg cggcggtgcc gggcgctgct
    14461 gactcaacgc ccagcgtacg tcccgtcagg gcacgacgtg tccggggacc accgggctgc
    14521 gggtcttctc ccactgcagg aagcgctcgg tctcggcgag caccgtaccg gccagccagg
    14581 tgaccaccac ggcgtcgtcc accaggccga acacgctcag catcaactcg ggcaccagat
    14641 ccaccgggga ggccacgtac gccaccgcgg cggtcatcag ggccagtcgc agaccgccgt
    14701 cgtactcgcc ccgcatgctg gcccggatca tccggggtac cgccgccacc cgggtgccca
    14761 gcgccggtcc accccgggac ccggcggcca gcgccctcgc caacgcggtg aacgccgcgg
    14821 tccgcttcag cgtcctaccc atcccgtcgc ctccttctgt cgtcgcccat
//
