LOCUS       NZ_BMMJ01000001        21872 bp    DNA     linear   CON 09-SEP-2024
DEFINITION  Micromonospora yangpuensis strain CGMCC 4.5736 sequence01, whole
            genome shotgun sequence.
ACCESSION   NZ_BMMJ01000001
VERSION     NZ_BMMJ01000001.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Micromonospora yangpuensis
  ORGANISM  Micromonospora yangpuensis
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 1021831)
  AUTHORS   Sun,Q. and Zhou,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 133X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014645775.1-RS_2024_09_09
            Annotation Date                   :: 09/09/2024 04:34:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,914
            CDSs (total)                      :: 5,857
            Genes (coding)                    :: 5,698
            CDSs (with protein)               :: 5,698
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 20 of 159
            Pseudo Genes (incomplete)         :: 144 of 159
            Pseudo Genes (internal stop)      :: 5 of 159
            Pseudo Genes (multiple problems)  :: 9 of 159
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:15:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 208572
            Orig. end                         :: 230444
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMMJ01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21872
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="blactam"
                     /region_number="1"
                     /rules="(BLS or CAS or tabtoxin)"
                     /tool="antismash"
     cand_cluster    1..21872
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(BLS or CAS or tabtoxin)"
                     /kind="single"
                     /product="blactam"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21872
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:11872](-)"
                     /cutoff="20000"
                     /detection_rule="(BLS or CAS or tabtoxin)"
                     /neighbourhood="10000"
                     /product="blactam"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11872)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(BLS or CAS or tabtoxin)"
                     /neighbourhood="10000"
                     /product="blactam"
                     /protocluster_number="1"
     gene            complement(92..1384)
                     /locus_tag="IEY64_RS00975"
                     /old_locus_tag="GCM10012279_01970"
     CDS             complement(92..1384)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (48-390). E-value:
                     6.7e-27. Score: 86.5. Matches aSDomain:
                     nrpspksdomains_IEY64_RS00975_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012382.5"
                     /locus_tag="IEY64_RS00975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_01970"
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_175440466.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1e-25, bitscore:
                     86.4, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRSPFARLRDLLRDVPAPAGWDPIPLHLGEARLVEPPLDVAALD
                     AVDGWTRYPELGGSAELRTAYLGWLARRFGGSFGEPADAGLMTDAELAADAGLAVEPTP
                     GSKQALAVVIAQAVRRARARGVTDPVVVLPNPGYPTYLAGTEAAGARPLCYPGTVDDGP
                     ADDGSGLADPVDALAAAVAAGAGRVAAVVVCHPGNPDGETLTAGQLARAAEVARRADAV
                     LVVDECYVDLWLGTAPAGFLSDPAALADPGLSFVVLHTLAKRSGAPGLRSGFVVGDRHT
                     VAAYAEYNRTCGVSLPRPVCAVSAALWSDDTHVARARAALARNWDTADELLKDLPGYRR
                     PGAGFFLWLPVPDDPGTTRRLWRDQALTVMPGRYLAVDTAAGSNPAAAGKDPGVDTAAG
                     SNPGAGHLRVALVHDEARTEVALTRLRAGLT"
     aSDomain        complement(215..1240)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEY64_RS00975_Aminotran_1_2.1"
                     /evalue="6.70E-27"
                     /label="IEY64_RS00975_Aminotran_1_2.1"
                     /locus_tag="IEY64_RS00975"
                     /protein_end="390"
                     /protein_start="48"
                     /score="86.5"
                     /tool="antismash"
                     /translation="GWTRYPELGGSAELRTAYLGWLARRFGGSFGEPADAGLMTDAELA
                     ADAGLAVEPTPGSKQALAVVIAQAVRRARARGVTDPVVVLPNPGYPTYLAGTEAAGARP
                     LCYPGTVDDGPADDGSGLADPVDALAAAVAAGAGRVAAVVVCHPGNPDGETLTAGQLAR
                     AAEVARRADAVLVVDECYVDLWLGTAPAGFLSDPAALADPGLSFVVLHTLAKRSGAPGL
                     RSGFVVGDRHTVAAYAEYNRTCGVSLPRPVCAVSAALWSDDTHVARARAALARNWDTAD
                     ELLKDLPGYRRPGAGFFLWLPVPDDPGTTRRLWRDQALTVMPGRYLAVDTAAGSNPAAA
                     GK"
     gene            complement(1390..2220)
                     /locus_tag="IEY64_RS00980"
                     /old_locus_tag="GCM10012279_01980"
     CDS             complement(1390..2220)
                     /EC_number="2.3.1.117"
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008035733.1"
                     /locus_tag="IEY64_RS00980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_01980"
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-succinyltransferase"
                     /protein_id="WP_091435363.1"
                     /transl_table=11
                     /translation="MTDEQSRTYVEQAFARRDRLTPDEVAELRPYVEAGLAGLDRGELR
                     AARPEGDTWIVDAYTKQVILLSFLTHPNLMAQSGPGRPRTYDKVPLKFETWTADDFEKS
                     RLRVVPGAVVRYGSHIAPGAVLMPSFVNVGAYVGAGTMVDTWATIGSCAQIGQRCHISG
                     GAGIGGVLEPLGEQPVVIEDDVFVGARCEIAEGVRVRAGAILGMGVYLGRSTPIVDRAS
                     GAVSYGEVPPNAVVVPGSRAVAQQPGLSLAAAVIVKYADERTRGKTALNDLVRD"
     gene            complement(2217..3470)
                     /locus_tag="IEY64_RS00985"
                     /old_locus_tag="GCM10012279_01990"
     CDS             complement(2217..3470)
                     /EC_number="4.1.1.20"
                     /GO_function="GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_DAP_Arg_deC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264: diaminopimelate decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014803.5"
                     /locus_tag="IEY64_RS00985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_01990"
                     /product="diaminopimelate decarboxylase"
                     /protein_id="WP_091435362.1"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 1.2e-38, bitscore:
                     128.7, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 1.1e-18,
                     bitscore: 63.2, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPISQEFAARLLPVLPAVVETYPTPFHIYDERGIVDTHRELVAAF
                     DGAPYRQYFAVKALPNPTVLRTLLAEGSGLDCASPVELELAERLGARADDVVFTSNNTT
                     VAEYESALKAGALITFDDRSLLDKVDRLPELVAFRVAPHGTAAGSALMGSATHSKFGVP
                     LAELADAYRAAHRRGVRRFGIHGMICANELNLERAVRAAVEVVELGARIAAETGIELEY
                     VNIGGGLGIPYRPTERPIDIRAYASAILAARRRAFTTHRPRIVTEIGRYLTGPHGVLVS
                     QVVNRCRKGQDIVGLDASMSALMRPGYYGAYHHISLPYAAGRPETLVDVVGSLCENNDK
                     FGVDRLLPAPAEGDIALIHDTGAHGHAMGFTYNGRLRPAELLLTAAGEVVEIRRAETFD
                     DYLATARWTPTKIMESTR"
     gene            complement(3472..4170)
                     /locus_tag="IEY64_RS00990"
                     /old_locus_tag="GCM10012279_02000"
     CDS             complement(3472..4170)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY64_RS00990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10012279_02000"
                     /product="oxin biosynthesis protein"
                     /protein_id="WP_091435361.1"
                     /transl_table=11
                     /translation="MIKVEQHLEQVREYYRTHRSVDGQAEGTIYAIWERGRAFNDSVTP
                     STYVPEYRSHMTLKLLSLTAPGAAVFSLGCGNGFVEGDLVALDRTVRAIDFNDEAVALT
                     RGRGVDAFVADYFDLTPADLAGTDLLYADGFLGHVFTAEETVTPALAQLTGLGLRSGAY
                     VVLSNDAPYDPAADYAPHERVAGFWFVSREYLGQELARAGLVPVESYYFPYLRPISGLR
                     NRTICVARVP"
     gene            complement(4167..5540)
                     /locus_tag="IEY64_RS00995"
                     /old_locus_tag="GCM10012279_02010"
     CDS             complement(4167..5540)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY64_RS00995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10012279_02010"
                     /product="hypothetical protein"
                     /protein_id="WP_091435359.1"
                     /transl_table=11
                     /translation="MPDTDRFDYADNLTRAGRYRDHRGAFWPPTASYRPIGLDLAPATP
                     QLDADFPTALAGLRTAIEAEWAGAKEHGIAVPRRLADPAVTAAALRRVAGLLPAEADRR
                     AASLRADAVEHGYTDEILKELTGLVEEVTLVAGQVSTWYGKDIRGLPTAFACRRDDQRQ
                     ADVDRALEFLPDVPPYLGRLHADLRLGDLPAFGAAQLFFMAGEGDLHPKHIAYFLPEDE
                     GVKYSPFKKTYYFANVHRALVRGVSGPLAADLLTLDTPVDLDDERFATIGTLGVLSHEF
                     GHFVQRPATSFKELNAADRWASVVLQEVAADVFGILILAEVWAERLALTPADVIAYYLA
                     ECLRYVSRGLGHFPDSDGMYLQLSYLVQVGALETDGVRLVGGHSAVVAGLRSLARVLAD
                     FLLAGDAELAGRLHHDYGPANPAPLRALVDALRRRPAGSVEYGQSHTTIATADGENQQ"
     gene            complement(5588..7441)
                     /locus_tag="IEY64_RS01000"
                     /old_locus_tag="GCM10012279_02020"
     CDS             complement(5588..7441)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF005543.0"
                     /locus_tag="IEY64_RS01000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_02020"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_091435357.1"
                     /transl_table=11
                     /translation="MTGAPVTVGPGDPESAGVTVGPGDPDDAEVAALLRRSEEYAHSLY
                     PPESVHLLPVAELRAPSVAFLVARDAATGALLGCGAVVLPEPAAGTLADGADRAERAGA
                     GAYAEVKRMFVEPGVRRRGVGARILAALEQRVRAAGVGTVRLETGPDQPEAIALYRRLG
                     YVERGRFGDYPDDPLSIFMEKALDPPGAGQEQGSGMDTTPRPVLVVVDGYSSGAQLPGL
                     LRERGWDCVHVQSSPDLPPYFLASFDSTAWIDRYGYLGDLGALTDVLARYRPAAVLPGS
                     ESGVALADLLAEALGLPGNSPQSSAARRHKYEMHNRLKAAGLRSMDHYLAGDLAGLLDW
                     AGGGSWPVVLKPPASAGTDSVTFCADAGELTGAFQRLHGAVDQLGNRNDTLVAQRFLTG
                     QEYFVNGISGDGRHVVTEIWRTDKIRVPGGGWIYDRSVLFDPTQPEQKELVDYVHGVLD
                     ALGVSYGAHHTELMVGPDGPTLVECASRISGGLNRPAAAHAVGASMLDLVTEIVVEGPG
                     FVPRYADSRPGHAAPLWQVQFISTVDGVVVESHYAELLASLRSRTWLQRAPRPGDRVYR
                     TNDLFSSPGIVFMTHPDVDVLAADHALVRQWEQENRLFTVA"
     gene            complement(7438..9048)
                     /locus_tag="IEY64_RS01005"
                     /old_locus_tag="GCM10012279_02030"
     CDS             complement(7438..9048)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012935.5"
                     /locus_tag="IEY64_RS01005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_02030"
                     /product="GMC family oxidoreductase"
                     /protein_id="WP_091435355.1"
                     /transl_table=11
                     /translation="MATYDYVVVGAGAAGCVLAGRLTEDPTVSVLLLESGRQRRSPLLS
                     IPAAETILMGNPRYDWCFDTEADPTIDGRSLRIPRGRLLGGSNAINGMIFVRGQRQDYD
                     DWAALGNPGWSWEGVLPYFRSMERVAGIGGDSRGRSGPIAVGLPRERDELCDAFLTAAG
                     KAGYPENPDYNSGDQEGFGYYQVNHDGGRRSSALGGYLRPARQRPNLTVLTGAHVGRLR
                     FDGTRCVGVTYRHGGAEHTADCGREVIVSAGTVQSPQLLELSGVGPAEVLRNAGVPVVH
                     HLPGVGENFRDHFAARLRWRVRQPITFNERSRGVRLAGEVLRYLGTRRGLLSLPIALGH
                     GFVRTSDTLDRPDVQFHFAPASYGAGSTRRLDTRPGMTVGVYPLRPESKGSIHIRSADP
                     EQPPAIRPRFLDTELDRATLLAGMRIARRIVEGAPLDAYREFETQPGPDVRTDDELLAY
                     ARERGDTSYHPVGTCRMGDDPGAVVDERLRVRGLAGLRVIDASVMPTMISGNTNAASMM
                     IGEKGAALVRQDHRAGAAR"
     gene            complement(9051..9899)
                     /locus_tag="IEY64_RS01010"
                     /old_locus_tag="GCM10012279_02040"
     CDS             complement(9051..9899)
                     /NRPS_PKS="Domain: TauD (5-273). E-value: 6.7e-66. Score:
                     214.7. Matches aSDomain:
                     nrpspksdomains_IEY64_RS01010_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1121: dioxygenase, TauD/TfdA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014698.5"
                     /locus_tag="IEY64_RS01010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_02040"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_091435353.1"
                     /sec_met_domain="TauD (E-value: 1e-64, bitscore: 214.7,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLELVPLAEGVGTEVRGIDVTGDISDRDFARIHRAWMDTAVLLFR
                     DQKLTPEQHIAFTRRFGEVFAYTRSQFNDVEHPEILLLSNLTRDGKPIGSAYSGRVWHT
                     DGHYLTNPPVGSMLYAIEVPPVGGDTWYANMYAAYEALPERVKERIEDLRVVISRVQSR
                     PYNYPDRPAPTEQERAEWVDVSHPIVRRHEVSGRKALYAGGNVPWRIEGLPVHESAPLV
                     TFIQEFAVQPRFTYRHQWRPGDIVLWDNRGAMHRATYYNDVAHRRLLHRTTIATDRPIP
                     A"
     aSDomain        complement(9081..9884)
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEY64_RS01010_TauD.1"
                     /evalue="6.70E-66"
                     /label="IEY64_RS01010_TauD.1"
                     /locus_tag="IEY64_RS01010"
                     /protein_end="273"
                     /protein_start="5"
                     /score="214.7"
                     /tool="antismash"
                     /translation="PLAEGVGTEVRGIDVTGDISDRDFARIHRAWMDTAVLLFRDQKLT
                     PEQHIAFTRRFGEVFAYTRSQFNDVEHPEILLLSNLTRDGKPIGSAYSGRVWHTDGHYL
                     TNPPVGSMLYAIEVPPVGGDTWYANMYAAYEALPERVKERIEDLRVVISRVQSRPYNYP
                     DRPAPTEQERAEWVDVSHPIVRRHEVSGRKALYAGGNVPWRIEGLPVHESAPLVTFIQE
                     FAVQPRFTYRHQWRPGDIVLWDNRGAMHRATYYNDVAHRRLLHRTT"
     gene            complement(10001..11872)
                     /gene="asnB"
                     /locus_tag="IEY64_RS01015"
                     /old_locus_tag="GCM10012279_02050"
     CDS             complement(10001..11872)
                     /EC_number="6.3.5.4"
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="asnB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     blactam: tabtoxin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR01536.1"
                     /locus_tag="IEY64_RS01015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_02050"
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="WP_308472661.1"
                     /sec_met_domain="tabtoxin (E-value: 8.6e-229, bitscore:
                     756.7, seeds: 3, tool: rule-based-clusters)"
                     /sec_met_domain="GATase_7 (E-value: 1e-28, bitscore: 95.5,
                     seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 1.3e-77, bitscore:
                     257.6, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDDRAGTGDQRMSGIAGWIDFRRDIGTRSSILRAMTGTMRDRGP
                     DSAGVWMSAHAGLGYRGLDTGAPGGSGNLARVEFGDAAVTLVHAGPIYNLRELRRAVEA
                     AGTRRRAESTPEILLETYLRHGERFVEQLDGMFTVAVWDGRHRRLLLARDRLGLKPLYY
                     HRYADGVVFASEPTAVLTHPLVTARLELAALPIVLQPRLTRAGETPLVGLRELAPAELL
                     GCTAEGTTSRRYWELTSAPHHDSFDKTAAHVRELLEESVGRQLATGVPGGAMLSGGVDS
                     TSVAALAAQLLGGGGQRLDTYCVEFASDPSHFTPTELRPDVDAPYAAAAAEFLGTRHHT
                     LTASVEDLLAAIPATRRARGLPGWGQFDASMYLIFQQMRERSVVALTGEAADEFLGGYP
                     YFFKADRLERDTFPWIGDGPRLVDYLAPELRDVVRPAADERDRYHDLLGQVPRLPGEDP
                     ADARMREVFYLGMAGPLAVILDRKERMSMAHGLEVRVPFCDHRLVEYLWNVPWSMKSAG
                     GVKGLLKAAMADLLPPGTVNRRKSAYPHVQSPRYDEALIREATWIVNDPASSLRAMFDT
                     ARLNGLIRQITAGRMDSELPGGASPAHLLIQLVELRAWIEENKVALP"
     misc_feature    complement(11919..11928)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.59"
                     /tool="antismash"
     misc_feature    complement(11996..12013)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.38"
                     /tool="antismash"
     misc_feature    12032..12046
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.96"
                     /tool="antismash"
     gene            complement(12411..13718)
                     /locus_tag="IEY64_RS30210"
                     /old_locus_tag="GCM10012279_02060"
     CDS             complement(12411..13718)
                     /NRPS_PKS="Domain: AMP-binding (78-422). E-value: 2.2e-16.
                     Score: 51.3. Matches aSDomain:
                     nrpspksdomains_IEY64_RS30210_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012711.5"
                     /locus_tag="IEY64_RS30210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_02060"
                     /product="AMP-binding protein"
                     /protein_id="WP_175440465.1"
                     /sec_met_domain="AMP-binding (E-value: 3e-15, bitscore:
                     51.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFGREELRYVQLVATEAREFAVWPIGRRPPRGWRVVPFAGTLAAC
                     GRHVAELHHAAATRSGGGQAPQSAGHELVGLLAKAAGEQPDAVALSAGALRMTYRQLWE
                     HVEELAARLGEAGVGPGGRVAVVGRPPADLVVVVVAVLVAGATCVLAEGGSPEATGEAV
                     RAVRPDLVLAPAGTPCVPPWWPEARCHWSGPTGSTWHAWGTTEQAAGTGGRVATPASAP
                     VTGGAPAEAALVVSASPDGTGVVWRGQQLAWLAGGCGLPRLGCGDRLLPLAPLDATTTL
                     VVALRALLTGAELALPADGDRSSATGPVPARWRLRVERADGSVDEIQVFGFAETTMLAA
                     TVDPATGELTPLPQTRGCVLDGHLASVPRGQVGELYLAGTPLAAGYLDRPELTMGRFLP
                     DPSGAAPGSLMFRTGLLARQVAEQRFSLVGPASTGS"
     aSDomain        complement(12453..13484)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEY64_RS30210_AMP-binding.1"
                     /evalue="2.20E-16"
                     /label="IEY64_RS30210_AMP-binding.1"
                     /locus_tag="IEY64_RS30210"
                     /protein_end="422"
                     /protein_start="78"
                     /score="51.3"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="KAAGEQPDAVALSAGALRMTYRQLWEHVEELAARLGEAGVGPGGR
                     VAVVGRPPADLVVVVVAVLVAGATCVLAEGGSPEATGEAVRAVRPDLVLAPAGTPCVPP
                     WWPEARCHWSGPTGSTWHAWGTTEQAAGTGGRVATPASAPVTGGAPAEAALVVSASPDG
                     TGVVWRGQQLAWLAGGCGLPRLGCGDRLLPLAPLDATTTLVVALRALLTGAELALPADG
                     DRSSATGPVPARWRLRVERADGSVDEIQVFGFAETTMLAATVDPATGELTPLPQTRGCV
                     LDGHLASVPRGQVGELYLAGTPLAAGYLDRPELTMGRFLPDPSGAAPGSLMFRTGLLAR
                     QVAE"
     CDS_motif       complement(12528..12617)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IEY64_RS30210_0001"
                     /evalue="5.50E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="IEY64_RS30210"
                     /protein_end="397"
                     /protein_start="367"
                     /score="37.9"
                     /tool="antismash"
                     /translation="PRGQVGELYLAGTPLAAGYLDRPELTMGRF"
     gene            complement(13869..14552)
                     /locus_tag="IEY64_RS01025"
                     /old_locus_tag="GCM10012279_02070"
     CDS             complement(13869..14552)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007074874.1"
                     /locus_tag="IEY64_RS01025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_02070"
                     /product="response regulator transcription factor"
                     /protein_id="WP_229688095.1"
                     /transl_table=11
                     /translation="MSIPVRSQIRVCLADDHNLLRDGIREMLSTEPEFAVVGEASSGPE
                     ALAMVARLRPEVLLLDVEMPGPGARAVIRQARQVAPETRVIVLTMHDDPDMVHELLEAG
                     AVAYLLKTILRDDLIAAVRSVVRRPSQSVLLAVSRETVERLDRQKPRTTGTPLTARELE
                     VLRLIAEAMSNAQIASRLFITEATVKRHLTNIYAKLHAVSRVDAIRKATAARLIKPMDD
                     HPTVF"
     gene            complement(14549..15613)
                     /locus_tag="IEY64_RS01030"
                     /old_locus_tag="GCM10012279_02080"
     CDS             complement(14549..15613)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019350.5"
                     /locus_tag="IEY64_RS01030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_02080"
                     /product="sensor histidine kinase"
                     /protein_id="WP_189021528.1"
                     /transl_table=11
                     /translation="MGPVGEVELSSTAREIVAAFQDSLRRQGNELVTGPEVVAQLAIQV
                     QSVLDDIEARLSGADATSVELVGESRLFNVDIGADRARRGIHPVQSLRAATTLFEVMLR
                     ILTRDLPPTDSAAALRLSRALHEAIMARVALASLSYVGFLMEKLQASRQEERTRIAREL
                     HDRVLHEMGLTLHRLDLHRHYADRDPAQARAKVDAAIESLDEALRTVRTLSAELRRSVG
                     EYGLERTLRAYLEANAPTSVQFSVTTTGDVKALPPDVSEELYLIMREAARNALRHADPG
                     RLELSIDVGDDAVAAAVVDDGAGFDTGDPDRARGGLPSMYERALLLHGVLTLTSAPGSG
                     TRVEVRIPFSEAGL"
     misc_feature    15733..15746
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.09"
                     /tool="antismash"
     gene            complement(15782..16738)
                     /locus_tag="IEY64_RS01035"
                     /old_locus_tag="GCM10012279_02090"
     CDS             complement(15782..16738)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ubiA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013226.5"
                     /locus_tag="IEY64_RS01035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_02090"
                     /product="UbiA family prenyltransferase"
                     /protein_id="WP_091435345.1"
                     /sec_met_domain="ubiA (E-value: 3.4e-23, bitscore: 78.2,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTYSVNGLDRYFRVDGPVRPAVPALAAIAQGGGQVVASWREARPV
                     VQVIFQLRFFAGAAVAAPHAVVTRPGALLLGSLAWLCATWFVYLLNGLNDQVEDRRNGS
                     HRPLATGALPTAAARRIAVGLAAAALLLGAAVSLRLAGLVAVMLLLGWLYSAGPRPQKG
                     NMLGFVLVVAAGGVVTYLAGSAAAGGLFEPELVVLMLAMSMWMALAGTTKDLSDVAGDR
                     AAGRRTLPVLLGDHGARRLMAALVALAGGVLLIGALLVTPTLAAPAAVLTVGATAVVGC
                     LLAGTGATDRRRQRRPYRIFMVSQYAVHLTVLSQFVN"
     gene            16941..17651
                     /locus_tag="IEY64_RS01040"
                     /old_locus_tag="GCM10012279_02100"
     CDS             16941..17651
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015649.5"
                     /locus_tag="IEY64_RS01040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_02100"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_091435343.1"
                     /transl_table=11
                     /translation="MSYHAESSTAELFGGFQITIHGNPVTNWRAGRSRALVQYLLLHVG
                     RPVSRDTLREALWPHLPPSAGTTSVKAAVHGARRALGGPAGRPTPVQICSVDGGYLLRA
                     DELRIDVTTFGRWIANAEAAVAAGNHAAAAEHFHRAVAVYQGPLLPTQDAQWVVTEREW
                     CRTRALQALRYLSDLALTTGDWWTAIHWNRRAIDVDPYDPVAFAVLTDCHHRLGLTSQA
                     LRWDDLARGRLAEV"
     gene            17692..17937
                     /locus_tag="IEY64_RS01045"
                     /old_locus_tag="GCM10012279_02110"
     CDS             17692..17937
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IEY64_RS01045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10012279_02110"
                     /product="DUF1178 family protein"
                     /protein_id="WP_139135618.1"
                     /transl_table=11
                     /translation="MTTTQLRPAVTTAPGPVRPVDARPSVAASGTGLAPPEPATSPTPP
                     RSLPTRWRAGLRRARRFLLSTADDCPPMLLRLTQRN"
     misc_feature    complement(18134..18148)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.4"
                     /tool="antismash"
     gene            18193..19203
                     /locus_tag="IEY64_RS01050"
                     /old_locus_tag="GCM10012279_02120"
     CDS             18193..19203
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007074869.1"
                     /locus_tag="IEY64_RS01050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_02120"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_091435341.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.4e-35,
                     bitscore: 117.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAADEQTVSVIVPNYNYEKTLGACLDAVFAQTHRPYEVIVVDDGS
                     TDRSREIAARYPCRIVAGGGNKGVSAARNIGAREATGEILFFVDSDVALRPDAIANALA
                     VLAADPECGCVHGTYDTRPLYDDGPIEHYKVLHAHWWRRRSVGRVSTAVFALAAVRRSV
                     FAAAGRFHEGLRDAEDVEYSDRLVRVAGIRLTDTVVGRHDDCAGFRAMLREQYRRSLPL
                     AAFAGSHRMRAGSVAVNPALGVLVAPLVLLSLPLGLVHPALWAVPVVCFGLFLLADPGL
                     LPFVRRERGSAFLAYFVGVHLVAQLAIVAGAAVGLLTRLRGTATPQPLSLAEARR"
     gene            19200..20264
                     /locus_tag="IEY64_RS01055"
                     /old_locus_tag="GCM10012279_02130"
     CDS             19200..20264
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015651.5"
                     /locus_tag="IEY64_RS01055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_02130"
                     /product="lysylphosphatidylglycerol synthase transmembrane
                     domain-containing protein"
                     /protein_id="WP_091435339.1"
                     /transl_table=11
                     /translation="MNAPGGPGTAPATNAGGRDAGPTAEATNAPGGPGGRHRWRRVLRP
                     VLTVAFVAAVVGGVTVALRGQQWSALGRLLRPETAGWLFAALVVTAVGLLCGTRAWTLT
                     LAALGAPVPTGAGIRMFFVGFLGKFVPGRLWGLLAQLRLGEQAGVSRVRMAGTYLVNLV
                     VVMLTGGAVGLLVAPAVLGTGLAWLLVPVALLAVLVVRPGVIDTLVALAARVTRRPPPA
                     TLTRPADVRRSIGYQSLSWVLSGVHLWVLAVLLGAEAGTALPVAVGAFALATTAGTLAL
                     FVPDGAGVREVIVVAALATVLPLPAAVTAAIASRVLTTLAEILTAGTALAAVALRERAT
                     RPATARLTPTPTTS"
     gene            20398..21726
                     /locus_tag="IEY64_RS01060"
                     /old_locus_tag="GCM10012279_02140"
     CDS             20398..21726
                     /NRPS_PKS="Domain: Aminotran_3 (11-344). E-value: 9.5e-64.
                     Score: 207.5. Matches aSDomain:
                     nrpspksdomains_IEY64_RS01060_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018811076.1"
                     /locus_tag="IEY64_RS01060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10012279_02140"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_217628914.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.2e-61, bitscore:
                     204.4, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSFGFGRELADHAQGAYIHTRDGRAILDFTGGVGVLSHGHNHPR
                     ILAARQRFQARQRMEVHKTYFSPYLAALSHNLAEVLPGDLDMSFLPNSGAEAVEGAVKL
                     AYKYHGGRRNTILRSDISFHGKLLGSGSLTGSAQNHFAFPGIPGVVSFGYDDLASVRAA
                     VDASRDRRGRSDVYALLIEPFSASTMRWCSEEFLRGVRELCTREEIVLIFDEIYTGWGK
                     TGSMFYFMRYPGLIPDVVTTSKSFGGGKSSISAYVARRPIFHKAYESFNDALLQSTSTT
                     YYGFGEETATAIEAINVAVEEDFPARARDIERILAPGLARIAKEHPDAVSEVRGAGALW
                     GVFLNAPRALDAVAKLAPAGLARDPQFGTKLVTCAVVNALYRDHDIYTYYTLNGKNPLV
                     VGPPLVVDPVDVERFVDRLDQTLAQGLPRLVSRFVKEKVSSLW"
     aSDomain        20431..21429
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IEY64_RS01060_Aminotran_3.1"
                     /evalue="9.50E-64"
                     /label="IEY64_RS01060_Aminotran_3.1"
                     /locus_tag="IEY64_RS01060"
                     /protein_end="344"
                     /protein_start="11"
                     /score="207.5"
                     /tool="antismash"
                     /translation="DHAQGAYIHTRDGRAILDFTGGVGVLSHGHNHPRILAARQRFQAR
                     QRMEVHKTYFSPYLAALSHNLAEVLPGDLDMSFLPNSGAEAVEGAVKLAYKYHGGRRNT
                     ILRSDISFHGKLLGSGSLTGSAQNHFAFPGIPGVVSFGYDDLASVRAAVDASRDRRGRS
                     DVYALLIEPFSASTMRWCSEEFLRGVRELCTREEIVLIFDEIYTGWGKTGSMFYFMRYP
                     GLIPDVVTTSKSFGGGKSSISAYVARRPIFHKAYESFNDALLQSTSTTYYGFGEETATA
                     IEAINVAVEEDFPARARDIERILAPGLARIAKEHPDAVSEVRGAGALWGVFL"
ORIGIN
        1 ccgttgggcg atggccaccg gatcgacacc ggtgtcgacg gcctcgggca cctgttcacc
       61 gacggtcatc ggtcgtcctc ctcgatgcgg gtcacgtcag gcccgcccgt agccgggtca
      121 acgccacctc ggtccgggcc tcgtcgtgca cgagcgccac ccgcaggtga ccggcgcccg
      181 gattgctccc ggcggcggtg tcgacgcccg ggtctttccc ggcggcagcc ggattgctcc
      241 cggcggcggt gtcgacggcg aggtagcggc cgggcatgac ggtcagcgcc tggtcccgcc
      301 agagccggcg ggtggtcccg gggtcgtcgg gtaccggcag ccagaggaag aagccggcac
      361 ccggtcgccg gtagccgggc aggtccttga gcagctcgtc ggcggtgtcc cagttgcggg
      421 ccagggcggc gcgggcccgg gcgacgtggg tgtcgtcgga ccagagcgcg gcggagacgg
      481 cacagaccgg gcggggcagc gacaccccgc aggtgcggtt gtactcggcg taggccgcca
      541 cggtgtgccg gtcgcccacg acgaagccgc tgcgcaggcc gggcgctccg gagcgtttgg
      601 cgagggtgtg cagcaccacg aaggacagcc ccgggtcggc gagcgccgcc gggtcggaga
      661 ggaacccggc cggtgcggtg ccgagccaca ggtcgacgta gcactcgtcg accaccagca
      721 ccgcgtcggc ccgccgggcc acctcggcgg cgcgggcgag ctgcccggcg gtcaacgtct
      781 cgccgtccgg gttgccggga tggcagacca ccaccgccgc cacccgtccc gccccggcgg
      841 cgaccgccgc ggccagcgcg tccaccggat cggccagccc cgacccgtcg tccgccggcc
      901 cgtcgtccac cgtgccgggg tagcagagcg gtcgggcgcc ggcggcctcg gtgccggcca
      961 ggtaggtcgg gtagccgggg ttcggtagca ccaccaccgg gtcggtcacc ccgcgtgccc
     1021 gggcccgccg gacggcctgg gcgatcacca ccgccagcgc ctgcttgctc cccggcgtcg
     1081 gctccaccgc caacccggcg tccgccgcca gctccgcgtc cgtcatcagc cccgcgtccg
     1141 ccggttcacc gaaggacccg ccgaaccgcc gcgccaacca accgaggtac gccgtccgca
     1201 gctccgccga accacccagc tccggatagc gggtccagcc gtccacggcg tccaacgcgg
     1261 cgacgtccag cggcggttcg accagccggg cctcccccag gtgcagcggg atcgggtccc
     1321 accccgccgg ggcgggcacg tcgcgcagga ggtcccgcag tcgggcgaac gggctccgcg
     1381 tcacccggat cagtcccgca ccaggtcgtt cagggcggtc ttgccccggg tccgctcgtc
     1441 ggcgtacttg acgatgacgg cggcggccaa cgacagcccc ggctgctggg cgacggcccg
     1501 gctgccgggc accacgacgg cgttcggcgg cacctcgccg tagctcaccg caccgctggc
     1561 ccggtccacg atcggggtgg aacggcccag gtagacaccc atcccgagga tcgcgccggc
     1621 gcgtacccgg accccctcgg cgatctcgca gcgggcgccg acgaagacgt cgtcctcgat
     1681 gacgaccggc tgctcaccga ggggttccag cacgccgccg atgcccgcgc cgccggagat
     1741 gtggcagcgc tggccgatct gggcgcagga gccgatggtg gcccaggtgt ccaccatcgt
     1801 gcccgcaccg acgtacgcgc cgacgttgac gaaggacggc atcagcaccg cgccgggggc
     1861 gatgtggctg ccgtaccgga cgaccgcgcc cgggaccacc cgcagccggg acttctcgaa
     1921 gtcgtcggcc gtccaggtct cgaacttcaa cggcaccttg tcgtacgtcc tcggccgacc
     1981 cgggccggac tgcgccatga ggttgggatg ggtcaggaag gacagcagga tcacctgctt
     2041 ggtataggcg tcgacgatcc acgtgtcgcc ctccggccgg gccgcgcgca gctccccccg
     2101 gtccagcccg gccagccccg cctcgacgta cggccgcagt tcggccacct cgtccggggt
     2161 gagccggtcc cgccgggcga aggcctgctc gacgtacgtc cggctctgtt cgtcagtcac
     2221 ctggtgctct ccatgatctt cgtgggtgtc cagcgcgccg tggcgaggta gtcgtcgaag
     2281 gtctccgccc gacggatctc gaccacctcg ccggccgccg tcagcagcag ttcggccggc
     2341 cgcagccgtc cgttgtaggt gaaccccatc gcgtgcccgt gcgcgccggt gtcgtggatc
     2401 agcgcgatgt ccccctcggc cggggcgggc agcagccggt cgacgccgaa cttgtcgttg
     2461 ttctcgcaga gcgagcccac cacgtcgacg agcgtctcgg gtcggccggc ggcgtacggc
     2521 aggctgatgt ggtggtacgc gccgtagtag ccgggccgca tcagcgccga catcgaggcg
     2581 tccagcccga cgatgtcctg ccccttgcgg caccggttga ccacctggct gaccagtacg
     2641 ccgtgcggcc cggtcaggta ccgcccgatc tcggtgacga tccggggccg gtgggtggtg
     2701 aaggcccgcc gccgggcggc caggatcgcc gaggcgtacg cccggatgtc gatcggccgc
     2761 tcggtcggcc ggtacgggat gccgaggccg ccgccgatgt tgacgtactc cagttcgatg
     2821 ccggtctcgg cggcgatccg cgcacccagc tcgaccacct cgacggcggc ccggaccgcc
     2881 cgctccaggt tgagctcgtt ggcgcagatc atcccgtgga tgccgaaccg gcgtaccccc
     2941 cggcggtggg cggcccggta ggcgtcggcc agctcggcca gcggcacccc gaacttggag
     3001 tgggtggcgc tgcccatcag ggccgagccg gcggcggtgc cgtgcggcgc gacccggaag
     3061 gcgaccagct ccggcagccg gtccaccttg tccagcaggg accggtcgtc gaaggtgatc
     3121 aacgcgccgg ccttgagcgc cgactcgtac tcggcgaccg tggtgttgtt ggaggtgaag
     3181 accacgtcgt cggcgcgggc cccgagccgt tcggccagct ccagctcgac cggggaggcg
     3241 cagtccagac cactgccctc ggcgagcagg gtgcgcagca cggtcgggtt gggcagcgcc
     3301 ttgaccgcga agtactgccg gtacggcgca ccgtcgaagg ccgccaccag ctcccggtgg
     3361 gtgtcgacga tgccccgctc gtcgtagatg tggaaggggg tcgggtaggt ctcgaccacc
     3421 gccggcagca ccggcagcag ccgggcggcg aactcctgcg agatcggcat gtcagggcac
     3481 ccgggcgacg cagatggtcc ggttgcgcag cccgctgatc ggccgcaggt acgggaagta
     3541 gtagctctcc accggcacca ggccggcccg ggccagctcc tggcccaggt actcccggga
     3601 gacgaaccag aacccggcga cccgctcgtg cggggcgtag tcggccgccg ggtcgtacgg
     3661 ggcgtcgttg gagagcacca cgtacgcccc ggagcgcaac cccagcccgg tcagctgcgc
     3721 cagcgccggg gtgaccgtct cctcggcggt gaagacgtgg ccgaggaacc cgtcggcgta
     3781 gagcaggtcg gtgccggcca ggtcggccgg ggtcaggtcg aagtagtcgg ccacgaaggc
     3841 gtccaccccc cggccccggg tgagcgcgac cgcctcgtcg ttgaagtcga tcgcccgtac
     3901 cgtccggtcc agggccacca ggtcgccctc gacgaagccg ttgccgcagc cgagggagaa
     3961 gacggccgcg cccggtgcgg tcaacgacag cagcttgagg gtcatgtgcg accggtactc
     4021 gggcacgtag gtggaggggg tgaccgagtc gttgaacgcc cggccccgct cccagatggc
     4081 gtagatggtg ccctcggcct gcccgtcgac cgaacggtgc gtgcggtagt actcgcggac
     4141 ctgctccagg tgctgctcga ccttgatcac tgctggttct ccccgtcggc cgtggcgatc
     4201 gtggtgtgcg actgtccgta ctcgaccgag ccggccggtc gccggcgcag cgcgtcgacg
     4261 agggcccgca gcggtgccgg gttggccggc ccgtagtcgt ggtgcagccg accggccagc
     4321 tcggcgtccc cggcgagcag gaagtcggca agcacccggg ccagcgaccg cagcccggcc
     4381 accaccgcgc tgtgcccgcc gaccagccgg accccgtcgg tctccagcgc accgacctgc
     4441 accaggtacg acagctgcag gtacatgccg tcgctgtccg ggaagtggcc cagcccccgg
     4501 ctgacgtagc gcaggcactc ggccaggtag taggcgatca cgtcggccgg ggtcagggcg
     4561 agacgttcgg cccagacctc ggcgaggatc aggatgccga agacgtcggc ggcgacctcc
     4621 tggagcacca ccgaggccca ccggtcggcg gcgttgagct ccttgaagga ggtcgccggt
     4681 cgctgcacga agtgcccgaa ctcgtggctg agcacgccga gcgtgccgat ggtggcgaac
     4741 cgctcgtcgt cgaggtcgac cggggtgtcc agggtgagca ggtcggcggc gagcggcccg
     4801 gagacccccc gcaccagcgc ccggtgcacg ttggcgaagt agtaggtctt cttgaacggc
     4861 gagtacttga cgccctcgtc ctccggcagg aagtacgcga tgtgcttggg gtgcaggtca
     4921 ccctcgccgg ccatgaagaa cagctgcgcc gcgccgaacg ccggcaggtc acccaggcgc
     4981 aggtcggcgt ggagccgccc gaggtacggc gggacgtccg gcaggaactc cagcgcccgg
     5041 tccacgtcgg cctgccgctg gtcgtcacga cggcaggcga acgccgtcgg cagaccccgg
     5101 atgtccttgc cgtaccaggt ggaaacctgc ccggcgacca gggtgacctc ctcgaccagg
     5161 ccggtcagct ccttgaggat ctcgtcggtg tagccgtgct cgaccgcgtc ggcgcgcagc
     5221 gacgcggccc gccggtcggc ctcggccggc agcagcccgg cgacccggcg cagcgccgcc
     5281 gcggtgaccg ccgggtcggc caaccgccgg ggtacggcga tgccgtgctc cttggccccg
     5341 gcccactcgg cctcgatcgc ggtacgcagc ccggccagcg cggtggggaa gtcggcgtcc
     5401 agctgcgggg tggccggggc gaggtccagc ccgatcggtc ggtagcttgc cgtcggcggc
     5461 cagaaggcgc cccggtggtc gcggtaccgg ccggcgcggg tgaggttgtc ggcgtagtcg
     5521 aagcggtcgg tgtcaggcac gctggtgtcc cttctcaagg cgcggaacgg cccgctggtg
     5581 cggtgtctca ggcgacggtg aagagccggt tctcctgctc ccactgccgc acgagggcgt
     5641 ggtcggcggc caggacgtcg acgtccgggt gggtcatgaa gacgatgccg gggctggaga
     5701 agaggtcgtt ggtgcggtag acccggtcgc ccggtcgggg ggcccgctgc aaccaggtac
     5761 ggctgcgcag gctggccagc agctcggcgt agtgcgactc gaccaccacg ccgtcgacgg
     5821 tggagatgaa ctgcacctgc cagagcgggg cggcgtggcc gggccggctg tcggcgtacc
     5881 ggggcacgaa gccgggcccc tcgacgacga tctcggtgac caggtcgagc atgctcgcgc
     5941 cgacggcgtg cgcggcggcc ggccggttca gcccgccgga gatccgggag gcgcactcca
     6001 ccagggtcgg gccgtccggg ccgaccatca gctcggtgtg gtgggcgccg tagctgaccc
     6061 cgagcgcgtc gagcaccccg tgcacgtagt cgacgagttc cttctgctcg ggctgggtgg
     6121 ggtcgaacag gacgctgcgg tcgtagatcc agccgccgcc gggcacccgg atcttgtcgg
     6181 tgcgccagat ctcggtgacc acgtgccggc cgtcgccgct gatcccgttg acgaagtact
     6241 cctgcccggt caggaagcgt tgggcgacca gggtgtcgtt gcggttgccg agctggtcga
     6301 ccgcgccgtg caggcgctgg aaggccccgg tcagctcccc ggcgtcggcg cagaacgtca
     6361 ccgagtcggt gccggcgctg gccggcggct tgagcaccac cggccacgag ccgccgccgg
     6421 cccagtcgag cagcccggcc aggtcacctg ccaggtagtg gtccatgctg cgcaggccgg
     6481 ccgccttcaa ccggttgtgc atctcgtact tgtggcgtcg ggcggcgctg ctctgtgggg
     6541 agttgccggg caggccgagc gcctcggcga gcaggtcggc cagggcgacg ccgctctccg
     6601 agccgggcag caccgccgcc ggccggtacc gggccagcac gtcggtgagc gcgccgaggt
     6661 caccgaggta gccgtacctg tcgatccagg cggtggagtc gaagctggcc aggaagtacg
     6721 gcggcaggtc ggggctgctc tgcacgtgta cgcagtccca gccgcgttcg cgcagcaacc
     6781 ccggcagctg tgccccggag gagtagccgt cgaccaccac cagcaccggg cgcggtgtcg
     6841 tgtccatccc tgacccctgt tcctgtccgg cccccggcgg atcgagggcc ttctccatga
     6901 agatgctcag cgggtcgtcg gggtagtcgc cgaagcgtcc ccgctcgacg tagccgagtc
     6961 gccggtacaa cgcgatcgcc tcgggttggt ccggcccggt ctccagccgg acggtgccca
     7021 ccccggcggc ccggacccgc tgctccagcg cggcgaggat ccgggcaccg accccccggc
     7081 gacgcacgcc gggctcgacg aacatccgct tcacctcggc gtacgccccg gcaccggccc
     7141 gctcggcacg atccgcaccg tcggcgaggg tgccggcggc gggctcgggc agcaccaccg
     7201 cgccgcaacc cagcagcgca ccggttgccg cgtcgcgggc gaccaggaag gccaccgagg
     7261 gggcgcgcag ctcggccacc ggcagcaggt gcacgctctc cggcgggtac agcgagtggg
     7321 cgtactcctc ggagcgccgc agcagggcgg cgacctcggc gtcgtccggg tcacccggcc
     7381 cgacggtgac cccggcgctt tccgggtcac ccggcccgac ggtgaccggg gcgccggtca
     7441 ccgggcggcc cccgcccggt ggtcctgccg gaccagcgcc gcgcccttct cgccgatcat
     7501 catgctggcc gcgttggtgt tgccggagat catggtgggc atcaccgagg cgtcgatcac
     7561 ccgcaacccg gccagccccc gcacccgcag ccgctcgtcg accaccgcgc cggggtcgtc
     7621 gcccatccgg caggtgccca ccggatggta ggaggtgtcc ccccgttccc gggcgtacgc
     7681 cagcagttcg tcgtcggtgc ggacgtccgg accgggctgg gtctcgaact cccggtaggc
     7741 gtccagcggc gcgccctcga cgatccgccg ggcgatccgc atgccggcca gcagggtggc
     7801 ccggtccagc tcggtgtcga ggaaccgggg ccggatcgcc ggcggctgct ccggatcggc
     7861 gctgcggatg tggatggagc ccttcgactc cgggcgcagc gggtacaccc cgacggtcat
     7921 cccgggccgg gtgtccagcc gccgggtgga gcccgcgccg tagctggccg gggcgaagtg
     7981 gaactgcacg tccggccggt ccagcgtgtc gctggtgcgc acgaagccgt gcccgagggc
     8041 gatcgggagg ctgagcaggc cgcggcgggt gcccaggtag cgcagcacct cgccggccag
     8101 gcgtacgccc cgggagcgtt cgttgaaggt gatcggctgc cggacccgcc accgcagccg
     8161 ggccgcgaag tggtcccgga agttctcccc caccccgggc aggtggtgca ccaccggcac
     8221 cccggcgttg cgcagcacct ccgccgggcc gacgccggag agttccagca gttgcgggga
     8281 ctgcaccgtg ccggcgctga cgatcacctc ccggccgcag tcggcggtgt gctccgcgcc
     8341 gccgtgccgg taggtcaccc ccacgcagcg ggtgccgtcg aagcggagcc ggccgacgtg
     8401 cgcgccggtc agcacggtga ggttgggccg ctgccgggcc ggccgcaggt acccgcccag
     8461 cgccgacgac cgccgcccac cgtcgtggtt gacctggtag tagccgaacc cctcctggtc
     8521 gccggagttg tagtccgggt tctccgggta accggccttg ccggcggcgg tcaggaacgc
     8581 gtcgcagagc tcgtcgcgtt cgcggggcaa ccccaccgcg atcggcccgg accggccccg
     8641 gctgtccccg ccgatcccgg ccacccgttc catgctccgg aagtacggca gcaccccctc
     8701 ccacgaccac ccgggattgc ccagcgccgc ccagtcgtcg tagtcctggc gctggccgcg
     8761 tacgaagatc atgccgttga tggcgttcga tccaccgagc agccggcccc gggggatgcg
     8821 caggctccgc ccgtcgatgg tcgggtccgc ctcggtgtcg aagcaccagt cgtagcgcgg
     8881 gttgcccatc aggatcgtct cggcggccgg gatggacagc agcggactgc gccgctgccg
     8941 gccggactcc agcagcagca cgctcaccgt cgggtcctcg gtgagccggc cggccagcac
     9001 gcagcccgcc gcgccggcac cgacgaccac gtagtcgtac gtcgccatga tcaggccggg
     9061 atcgggcggt cggtggcgat ggtggtccgg tgcagcagcc ggcggtgcgc cacgtcgttg
     9121 tagtaggtgg cccggtgcat ggcgccccgg ttgtcccaga gcacgatgtc gcccggccgc
     9181 cactggtggc ggtaggtgaa ccggggctgc acggcgaact cctggatgaa ggtgaccagc
     9241 ggggcgctct cgtgcaccgg cagcccctcg atgcgccacg gcacgttgcc gccggcgtag
     9301 agcgccttgc ggccgctcac ctcgtgccga cgcacgatcg ggtgcgacac gtccacccac
     9361 tcggcccgtt cctgctcggt cggcgccggc cggtccgggt agttgtacgg ccgggactgg
     9421 acccggctga tcaccacccg caggtcctcg atgcgttcct tgacccgctc gggcagcgcc
     9481 tcgtaggcgg cgtacatgtt ggcgtaccag gtgtcgccgc cgaccggcgg cacctcgatg
     9541 gcgtagagca tcgagccgac cggcgggttg gtcaggtagt ggccgtcggt gtgccagacc
     9601 cgcccgctgt acgccgagcc gatcggcttg ccgtcgcggg tcaggttgga cagcaacagg
     9661 atctcggggt gctcgacgtc gttgaactgc gaacgggtgt acgcgaagac ctcaccgaag
     9721 cgccgggtga aggcgatgtg ctgctccggg gtcagcttct ggtcacggaa gagcaggacg
     9781 gcggtgtcca tccaggcccg gtggatgcgg gcgaagtcgc ggtcggagat gtcgccggtg
     9841 acatcgatgc cacggacctc ggtgccgacg ccctcggcga gggggaccag ttcgagcatc
     9901 agactgcctg cctttcgtct ggcggtgcgt caggggcgtg ggtgccgtcc ggcttggtgg
     9961 ccaccgtcgg ggtggccctc cggcccggtg gccggggtcg tcacggcagc gccaccttgt
    10021 tctcctcgat ccaggcccgc agctccacga gctggatgag caggtgcgcc gggctcgccc
    10081 cgcccggcag ttcggagtcc atccggccgg cggtgatctg ccggatcagg ccgttgagcc
    10141 gggcggtgtc gaacatcgcg cgcagcgacg aggccgggtc gttgacgatc caggtcgcct
    10201 cccggatcag cgcctcgtcg tagcgcgggc tctgcacgtg cgggtaggcg ctcttgcgcc
    10261 ggttgacggt gcccggcggg agcaggtcgg ccatggccgc cttgagcagc cccttcaccc
    10321 cgccggccga cttcatcgac cacggcacgt tccacaggta ctccaccagc cggtggtcgc
    10381 agaacggcac ccgtacctcc aggccgtggg ccatgctcat gcgttccttg cggtccagga
    10441 tcaccgcgag cggcccggcc atgccgaggt agaagacctc ccgcatccgg gcgtccgccg
    10501 ggtcctcccc gggcagcctc ggcacctggc cgagcaggtc gtggtaccgg tcccgctcgt
    10561 cggccgccgg ccgcaccacg tcgcgcagct cgggggcgag gtagtcgacc agccggggtc
    10621 cgtcgccgat ccaggggaag gtgtcgcgct ccagccggtc ggccttgaag aagtacgggt
    10681 acccgccgag gaactcgtcg gccgcctccc cggtcagcgc caccacgctg cgctcgcgca
    10741 tctgctggaa gatcaggtac atcgaggcgt cgaactggcc ccagccgggc agaccccggg
    10801 cccgacgggt agccgggatc gcggccagca ggtcctcgac gctggcggtc agggtgtggt
    10861 ggcgggtgcc gaggaactcg gccgccgccg ccgcgtacgg cgcgtccacg tccgggcgca
    10921 gctcggtcgg ggtgaagtgc gacgggtcgc tggcgaactc gacgcagtac gtgtcgagcc
    10981 gctgcccacc accgccgagc agctgcgccg ccagtgccgc gacggaggtc gagtcgaccc
    11041 cgccggagag catcgcgccg cccggcaccc cggtggccag ttgccggccg acgctctcct
    11101 ccagcagttc ccggacgtgc gcggcggtct tgtcgaacga gtcgtggtgc ggtgcgctgg
    11161 tcagctccca gtaccgccga ctggtggtgc cctcggcggt gcagccgagc agctcggccg
    11221 gggccagctc acgcagcccc accagcgggg tctcccccgc ccgggtcagc cgtggctgga
    11281 gcacgatggg cagcgcggcc agctccagtc gcgcggtgac caacgggtgg gtcaggaccg
    11341 ccgtgggctc ggaggcgaac acgacaccgt cggcgtaccg gtggtagtag aggggtttga
    11401 gtccgagccg gtcccgggcc agcaggagcc ggcggtgccg gccgtcccag acggcgacgg
    11461 tgaacatgcc gtcgagctgc tcgacgaagc gctccccgtg tcgcaggtac gtctccagca
    11521 ggatctccgg agtggactcg gcccgacgtc gggtgccggc cgcctcgacc gcccggcgca
    11581 gctcacggag gttgtagatc ggcccggcgt gcaccagcgt caccgccgcg tcgccgaact
    11641 ccacccgggc caggttcccg gagccaccgg gcgccccggt gtccaacccc cggtagccga
    11701 ggccggcgtg ggccgacatc cagacaccgg cactgtccgg accgcgatca cgcatcgtcc
    11761 cggtcatggc ccgcagaatg ctcgaccgcg taccgatatc tcggcggaag tcgatccagc
    11821 cggcaattcc actcatgcgt tgatctcccg tacccgcgcg gtcgtcggac attcgcccgg
    11881 cggcactgcc gagtcaagaa tcggccccag agaagtcttc aaaaatggcg gcaccgcgcc
    11941 tgcggccgta ccaccatggc accgaccagc cccgacgcat cgaggccatg cgccggaaac
    12001 acgttcgtaa aatagctccg actgattggc tggtcgatcc gttccgggcc acgacactgc
    12061 agttgacctg caaaaacacc accacgtcgg atgaatgtgc aatgccgcat cccggaacga
    12121 actcataatg accgtcgtcg gtacgcagca caagtagcca aaaagccagg taccgcatcc
    12181 tgggacagcc gcgaccgagt cggacgtaag cgcaggccaa cggccagatg cgagtggaac
    12241 ccgccacccc aacctggccg gaaatacact tcaccgacga acgaaacaat ccatcccgga
    12301 cgcatccacc atccacccac cggacacaac agacacccac cccaccggcc ggcgcccggc
    12361 gatcatgatg ttgttgccgc gacacgccgc tggtcggatg ggccgtccgg tcagctcccg
    12421 gtgctggccg gtccgaccag gctgaaccgc tgctccgcca cctgccgggc cagcaacccg
    12481 gtgcggaaca tgaggctgcc cggcgccgcg ccggacgggt cgggcaggaa ccggcccatg
    12541 gtcagctcgg gccggtccag gtagccggcg gccagcgggg tgcccgcgag gtacagctca
    12601 ccgacctgtc cccgggggac cgacgcgagg tgcccgtcca gcacgcaccc ccgggtctgc
    12661 ggcaacggcg tcagctcacc ggtcgccggg tccacggtcg cagccagcat cgtggtctcg
    12721 gcgaagccga acacctggat ctcgtcgacc gatccgtcgg cccgttcgac gcgcaaccgc
    12781 caccgggccg ggaccggccc ggtggccgac gaccggtcgc cgtcggcggg caacgccagc
    12841 tccgccccgg tgagcaacgc gcgcaacgcc accaccaggg tcgtcgtcgc atccagcggc
    12901 gccaacggca ggagccggtc gccgcaaccc agccggggca gcccgcagcc gccggcgagc
    12961 caggcgagtt gctggccgcg ccacaccacc ccggtgccgt ccggcgaggc cgacacgacc
    13021 agggccgcct ccgccggggc cccgccggtc accggtgcgc tcgccggggt ggccaccctc
    13081 ccaccggtcc cggcggcctg ctccgtggtg ccccaggcgt gccaggtgct cccggtcggg
    13141 cccgaccagt ggcagcgggc ctccggccac cagggcggca cgcagggcgt accggccggg
    13201 gccagcacca ggtcgggccg gacggcccgc accgcctcgc cggtggcctc cggcgacccg
    13261 ccttcggcca gcacacaggt ggccccggcg accagtaccg cgaccacgac gacgaccagg
    13321 tccgcgggcg gtcgcccgac gacggctacc cgtccacccg ggccgacgcc ggcctcgccg
    13381 aggcgtgcgg ccagctcctc gacgtgctcc cagagctggc ggtaggtcat ccgcagtgct
    13441 cctgcggaga gcgcgacggc atccggctgc tccccggcgg ccttggccaa cagcccgacc
    13501 agctcgtggc cggccgactg cggtgcctgc ccaccaccgc tgcgcgtcgc cgccgcgtgg
    13561 tgcagctccg ccacgtggcg accacaggcg gcgagggtgc ccgcgaaggg gacgacccgc
    13621 cagccccggg gaggtcgtcg accgatcggc cagaccgcga actccctggc ctcggtggcc
    13681 acgagttgga cgtagcggag ctcctctcgc ccgaacatgt gctgctccca gaagtgcgga
    13741 cccggacaac ggcatggacg acggcggtcg gcgaggatcc ggcaacaccc gcgacacctc
    13801 gtcgacatcc gaccccaccg aagctagcca gctccggtca caccccggtc atacccgccg
    13861 ggccgccctc agaagacggt gggatggtcg tccatcggct tgatcagccg ggcggccgtg
    13921 gccttacgga tggcgtccac ccgggacacg gcgtgcagct tggcgtagat gttggtcagg
    13981 tgccgcttga cggtcgcctc ggtgatgaac aaccggctgg cgatctgcgc gttgctcatc
    14041 gcctccgcga tgagccggag cacctccagc tcccgggcgg tcagcggggt gcccgtggtg
    14101 cgcggcttct gccggtccag ccgttccacg gtctcccgag agaccgccag caggacgctc
    14161 tggctgggcc ggcggaccac cgaccggacc gcggcgatca ggtcgtcccg caggatcgtc
    14221 ttgagcaggt acgcgaccgc gccggcctcc agcaactcgt gcaccatgtc cgggtcgtcg
    14281 tgcatcgtca gcacgatcac ccgggtctcc ggcgccacct gccgggcctg gcggatgacg
    14341 gcccgtgcac ccggaccggg catctccacg tcgagcagca gcacctcggg gcgcagccgg
    14401 gccaccatgg ccagcgcctc ggggccggac gacgcctcgc ccaccaccgc gaactccggc
    14461 tcggtggaga gcatctcgcg gatgccgtca cgcaacaggt tgtggtcgtc ggccaggcac
    14521 accctgatct gcgaccgtac gggaatgctc acagccctgc ctcggagaac gggattcgca
    14581 cctcgacgcg ggtaccgctg ccgggcgcac tggtcagggt caggacgccg tgcaacaaca
    14641 gcgcccgttc gtacatcgag ggcaggccgc cccgggcccg gtcggggtca ccggtgtcga
    14701 acccggcccc gtcgtcgacc accgcggcgg cgaccgcgtc gtcacccacg tcgatggaga
    14761 gctccagccg gccggggtcg gcgtgccgca acgcgttacg ggccgcctcc cgcatgatca
    14821 gatagagctc ctccgacacg tcgggcggga gcgccttgac gtcgccggtg gtggtcaccg
    14881 agaactgcac cgatgtcggc gcgttggcct ccaggtaggc acgcagggtg cgctccaggc
    14941 cgtactcgcc gaccgagcgg cgcagctcgg cggagagggt ccgcaccgtg cgcagcgcct
    15001 cgtccagcga ctcgatggcc gcgtcgacct tcgcccgggc ctgcgccgga tcgcggtcgg
    15061 cgtagtgccg gtgcaggtcc agccggtgca gggtcaggcc catctcgtgc agcacccggt
    15121 cgtgcagctc ccgggcgatc cgggtccgtt cctcctgccg ggaggcctgg agcttctcca
    15181 tcagaaaccc cacataggac agtgaggcca acgcgacccg ggccatgatg gcctcgtgca
    15241 gcgcccggct gagccggagc gcggcggcgc tgtcggtggg aggcaggtcg cgggtgagga
    15301 tccgcagcat gacctcgaag agggtggtcg ccgcgcgcag cgactgcacc gggtggatgc
    15361 cccggcgggc ccggtcggcg ccgatgtcga cgttgaagag tcgggactca cctaccagct
    15421 ccaccgaggt cgcgtcggca ccggagaggc gggcctcgat gtcgtcgagc accgactgga
    15481 cctggatcgc gagctgcgcc acgacctcgg ggccggtgac cagctcgttg ccctgccgac
    15541 ggagcgaatc ctggaaagcg gcgacaattt cccgtgccgt tgaggacaac tcgacctcac
    15601 ccacaggtcc catttcatgt ggtttcccca tggatccccc ctgtcacgcc cgagattacc
    15661 acaggtagcg cgtgggccgc gcagattaga tcatggccgc tggcaccaca aggtccagcg
    15721 gccacagtcg acgatacgcg tgtttccaag gcggcacgga agtgtgacga atagtcggct
    15781 gtcagttgac gaactggctc agcaccgtca ggtgaacggc gtactggctg accatgaaga
    15841 tccggtacgg gcggcgctgc cgccgccgat cggtcgcccc ggtgccggcc agcaggcagc
    15901 cgaccaccgc cgtcgcgccg acggtgagca cggccgccgg cgcggccagc gtcggggtca
    15961 ccagcagcgc gccgatcagc agcaccccgc cggccagtgc gaccagcgcg gccatcagcc
    16021 ggcgggcccc gtggtcgccg agcagcaccg gcagggtacg ccggccggcc gcccggtcac
    16081 cggcgacgtc ggagaggtcc ttggtggtgc cggccagcgc catccacatc gacatggcca
    16141 gcatcagcac caccagctcc ggctcgaaca ggccgcccgc cgccgcgctg ccggccaggt
    16201 aggtgaccac cccaccggcg gcgacgacca ggacgaagcc gagcatgttg cccttctgcg
    16261 ggcgcggacc ggccgagtac agccaaccga gcagcagcat caccgcgacc aggccggcca
    16321 gccgcagcga caccgccgcg cccagcagca gcgcggcggc ggccagcccg accgcgatcc
    16381 gacgggcggc ggcggtcggc agcgccccgg tggccaacgg ccggtgcgaa ccgttgcgcc
    16441 ggtcctcgac ctggtcgttc agcccgttga gcagatagac gaaccaggtc gcgcagagcc
    16501 aggcgagcga gcccagcagc agcgccccgg ggcgggtcac cacggcgtgc ggagcggcca
    16561 ccgcggcacc ggcgaagaac cgcaactgga agatgacctg gacgaccggg cgggcctccc
    16621 gccaactcgc caccacctgg ccaccgccct gggcgatggc tgccaacgcc ggcaccgccg
    16681 gccggaccgg gccgtcgacc cggaagtacc ggtcgagccc attcaccgag taggtcatgt
    16741 gaaacatcgt gaggccgcca caccttttcc ggttcatccg agccaccaac ccggactacg
    16801 acctaggtcg caggggtggc actaccaaac gctacttccc caccccggac aacacccgct
    16861 acctgcccgc cgcgacgcac gcaatttatg gtcgacctgt cgctcccacc cagccaacca
    16921 cggagcacag cggagtcctc atgtcgtacc acgcagaatc gtcgaccgcc gaactgttcg
    16981 gcggcttcca gatcaccatt catggcaatc ccgtgacgaa ctggcgggcc ggtcggtccc
    17041 gggcactggt gcagtacctg ctgctgcacg tcgggcggcc ggtcagccgg gacacgctgc
    17101 gtgaggcact ctggccgcac ctgccgccgt cggcgggtac cacctcggtg aaggccgcgg
    17161 tgcacggcgc gcggcgggcg ctcggcggcc cggccggccg accgacgccg gtgcagatct
    17221 gctcggtcga cggtggctac ctgctgcgcg ccgacgagct gcggatcgac gtcaccacgt
    17281 tcggcaggtg gatcgccaac gccgaggccg ccgtcgccgc cggcaaccac gccgcggccg
    17341 ccgagcactt ccatcgcgcg gtggcggtct accagggccc cctgctgccc acgcaggacg
    17401 cccagtgggt ggtgacggaa cgggagtggt gccggacccg ggccctgcag gcgctgcggt
    17461 acctcagcga cctggccctg accaccggcg actggtggac ggcgatccac tggaaccgtc
    17521 gggcgatcga cgtcgacccc tacgacccgg tggccttcgc cgtgcttacc gactgccacc
    17581 accggctcgg tctcacctcg caggcgctgc gctgggacga ccttgcccgg ggccggctgg
    17641 cggaggtgtg accgccaccg gatgccgaca acgcaactgg aaggagcaac cgtgaccact
    17701 acccaactgc gacccgcggt taccaccgca cccgggccgg tccggcccgt cgacgcccgg
    17761 ccttcggtgg cggcgtcggg gaccgggctc gccccgccgg agccggccac gtcaccgacc
    17821 ccaccccggt cgctgcccac ccggtggcgc gcgggcctgc ggcgggcccg gcggttcctg
    17881 ctgagcaccg ccgacgactg cccgccgatg ctgctgcgcc tcacccaacg caactgagag
    17941 caacccaccg aacgaaggca cccggtacgc cgactggcgt accgggtgcc tttctgtgcg
    18001 cgctccacgc gcaccattcc gggtacgccg caggaatgcg cttttggtcg tagtcgccct
    18061 tgccaccttc gaggagatcg gcaccggaaa aggattcgcc accttggccg gggatcgacg
    18121 gctgcctaac gtcatcgaca tcggagttcc tggacgtcac aaccgacgtc ggtcgtgaaa
    18181 gggagaggcc gaatggccgc tgatgagcag acggtgtcgg tgatcgtgcc gaactacaac
    18241 tacgagaaaa cgctcggcgc gtgcctggac gccgtgttcg cccagacgca ccggccgtac
    18301 gaggtgatcg tcgtcgacga cggctccacc gaccggtcga gggagatcgc ggcgcgctac
    18361 ccgtgccgga tcgtcgccgg cggcggcaac aagggcgtgt cggcggcccg caacatcggc
    18421 gcccgggagg cgaccggcga gatcctcttc ttcgtcgact ccgacgtggc gttgcgcccc
    18481 gacgcgatcg ccaacgcgct ggcggtgctg gcggccgacc cggagtgcgg ctgcgtgcac
    18541 ggcacctacg acacccggcc gctgtacgac gacgggccga tcgagcacta caaggtcctg
    18601 cacgcgcact ggtggcggcg gcgcagcgtc ggccgggtca gcaccgccgt cttcgcgctg
    18661 gccgcggtgc gccgctcggt gttcgccgcg gccggccggt tccacgaggg actgcgcgac
    18721 gccgaggacg tcgagtacag cgaccggctg gtgcgggtgg ccgggatccg gctcaccgac
    18781 acggtggtcg gccggcacga cgactgcgcc gggttccgcg cgatgctgcg ggagcagtac
    18841 cgccggtcgc tgccgctggc ggcgttcgcc gggtcgcacc ggatgcgcgc cggcagtgtc
    18901 gcggtcaatc ccgccctggg tgtgctggtc gccccgttgg tgctgctcag cctgccgttg
    18961 gggctggtgc acccggcgct ctgggcggta ccggtggtct gcttcgggct gttcctgctg
    19021 gccgacccgg ggctgctgcc cttcgtccgt cgcgagcgcg ggtcggcctt cctggcgtac
    19081 ttcgtcggcg tgcacctggt cgcccagctg gccatcgtgg ccggcgcggc ggtcggtctg
    19141 ctcacccggt tgcgcggcac ggccacgccg cagccgctga gcctggccga ggcccgccga
    19201 tgaacgcgcc gggcgggccc ggcacggccc cggcgacgaa cgcgggcgga cgcgacgccg
    19261 gcccgacggc ggaggcgacg aacgcgccgg gcggaccggg cggccggcac cgctggcggc
    19321 gggtgctgcg gccggtgctg acggtggcct tcgtggcggc ggtggtcggc ggggtcacgg
    19381 tggccctgcg cggacagcag tggtcggccc tgggccggct gctgcgcccg gagaccgccg
    19441 gctggttgtt cgccgcgctg gtggtcacgg cggtggggct gctctgcggc acccgtgcct
    19501 ggacgctgac cctggcggcc ctcggcgctc cggtgccgac cggggccggg atccggatgt
    19561 tcttcgtcgg cttcctcggc aagttcgtgc ccggccggct ctgggggctg ctggcccagc
    19621 tgcgcctcgg cgagcaggcc ggcgtcagcc gggtccggat ggccggcacg tacctggtga
    19681 acctggtcgt ggtgatgctg accggcgggg cggtggggtt gctggtcgcg ccggccgtgc
    19741 tcggcaccgg gctggcctgg ctgctcgtcc cggtcgcgct gctggcggtg ctggtcgtcc
    19801 ggcccggggt gatcgacacc ctggtcgcgc tggccgcccg ggtgacccgc cggccgcccc
    19861 cggccacgct cacccggccg gccgacgtcc ggcgctcgat cgggtaccag agcctgtcct
    19921 gggtgctctc cggcgtgcac ctgtgggtcc tcgcggtcct gctcggcgcg gaggccggga
    19981 ccgccctgcc ggtggccgtc ggcgcgttcg ccctggccac caccgccggc acgctcgccc
    20041 tgttcgtgcc ggacggcgcc ggggtccgcg aggtgatcgt ggtcgccgcc ctggccacgg
    20101 tgctgccgct gccggcggcg gtcaccgcgg cgatcgccag ccgggtgctc accaccctcg
    20161 ccgagatcct caccgccggc acggcgctgg ccgccgtcgc cctgcgggag cgggcgacgc
    20221 ggcccgcgac cgcccgactc acccccaccc ccaccaccag ctgaatcccc ctcctcaccc
    20281 atcctgaagg gacccaccat ggcgaagctc tacacggtcg acgcggccga gcagctctcg
    20341 atcgaccagg tgcagaacct gtaccgcaag tacgtgaaca agagccaggt cagcctgatg
    20401 acctcgttcg gcttcggccg ggagctggcc gaccacgccc agggcgccta catccacacc
    20461 cgcgacgggc gggccatcct ggacttcacc ggcggggtcg gggtgctcag ccacggccac
    20521 aaccacccgc gcatcctcgc cgcccgccag cgcttccagg cccggcagcg gatggaggtc
    20581 cacaagacct acttctcgcc gtacctggcc gcgctctcac acaacctggc cgaggtgctc
    20641 cccggcgacc tggacatgtc gttcctgccg aactccggcg cggaggcggt cgagggcgcg
    20701 gtcaagctgg cctacaagta ccacggcggc cggcgcaaca cgatcctgcg cagcgacatc
    20761 agcttccacg gcaagctgct cggctcgggc agcctgaccg gcagcgccca gaaccacttc
    20821 gccttccccg gcatcccggg cgtggtcagc ttcggctacg acgacctggc ctcggtccgg
    20881 gcggcggtgg acgccagccg ggaccggcgg ggccgaagcg acgtgtacgc cctgctgatc
    20941 gagccgttca gcgcctcgac gatgcggtgg tgctcggagg agttcctgcg cggggtgcgg
    21001 gagctgtgca cccgggagga gatcgtcctg atcttcgacg agatctacac cgggtggggc
    21061 aagaccggct cgatgttcta cttcatgcgc tacccggggc tgatcccgga cgtggtgacc
    21121 acctcgaagt ccttcggcgg cggcaagtcc tcgatctcgg cgtacgtggc ccgtcggccg
    21181 atcttccaca aggcgtacga gagcttcaac gacgccctgt tgcagagcac cagcaccacc
    21241 tactacggct tcggcgagga gaccgccacc gcgatcgagg cgatcaacgt ggcggtggag
    21301 gaggacttcc cggcccgggc gcgcgacatc gaacggattc tcgccccggg gctggcccgg
    21361 atcgccaagg agcaccccga cgcggtctcc gaggtacgcg gcgcgggtgc gctgtggggg
    21421 gtcttcctca acgccccgcg cgccctggac gccgtcgcca agctcgcccc ggccggcctg
    21481 gcccgcgatc cccagttcgg gacgaagctg gtcacctgcg cggtcgtcaa cgccctctac
    21541 cgggaccacg acatatacac gtactacacg ctcaacggaa agaatccgct ggtggtgggt
    21601 cccccactgg tcgtcgaccc ggtcgacgtg gagcgcttcg tcgaccggct cgaccagacc
    21661 ctcgcccagg gcctgccccg gctggtctcc cgtttcgtca aggagaaggt gtcgtcgctg
    21721 tggtgaacaa cgtgagtgcc aagacggtgg tggtgaccgg cggcagcgga atgctgggcg
    21781 ggcacctggt ccaggccctg gccgacgacg gctggcgggt gcgcagcctg gacgtgcggc
    21841 agccgatcga gccggtaccc ggcgtcgact ac
//
