LOCUS       NZ_CP061033            29862 bp    DNA     circular CON 27-APR-2024
DEFINITION  Corynebacterium zhongnanshanii strain zg-320 chromosome, complete
            genome.
ACCESSION   NZ_CP061033
VERSION     NZ_CP061033.1
KEYWORDS    RefSeq.
SOURCE      Corynebacterium zhongnanshanii
  ORGANISM  Corynebacterium zhongnanshanii
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Corynebacteriaceae; Corynebacterium.
REFERENCE   1  (bases 1 to 2206897)
  AUTHORS   Zhang,G.
  TITLE     novel species in genus Corynebacterium
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2206897)
  AUTHORS   Zhang,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-SEP-2020) Institute for Prevention and Control of
            Infectious Diseases, China Cdc, 155 Changbai Road, Changping
            District, Beijing, Beijing 102206, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 4.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 1910.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014490575.1-RS_2024_04_27
            Annotation Date                   :: 04/27/2024 03:58:32
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,980
            CDSs (total)                      :: 1,920
            Genes (coding)                    :: 1,906
            CDSs (with protein)               :: 1,906
            Genes (RNA)                       :: 60
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 14
            CDSs (without protein)            :: 14
            Pseudo Genes (ambiguous residues) :: 0 of 14
            Pseudo Genes (frameshifted)       :: 2 of 14
            Pseudo Genes (incomplete)         :: 12 of 14
            Pseudo Genes (internal stop)      :: 2 of 14
            Pseudo Genes (multiple problems)  :: 2 of 14
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:15:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2069499
            Orig. end                         :: 2099361
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP061033.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..29862
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="6"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..29862
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..29862
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:19862](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..19862
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    complement(111..126)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.45"
                     /tool="antismash"
     CDS             204..308
                     /gene="allorf_2069703_2069807"
                     /locus_tag="allorf_2069703_2069807"
                     /protein_id="allorf_2069703_2069807"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MISRGGTRGVAGDIATGHAHQDGGVACCSCVLTR"
     CDS_motif       204..254
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MISRGGTRGVAGDIATG"
                     /locus_tag="allorf_2069703_2069807_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       255..308
                     /prepeptide="core"
                     /locus_tag="allorf_2069703_2069807_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.20"
                     /molecular_weight="1720.9"
                     /monoisotopic_mass="1719.8"
                     /core_sequence="HAHQDGGVACCSCVLTR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MISRGGTRGVAGDIATG"
                     /leader_location="[203:254](+)"
     gene            complement(317..520)
                     /locus_tag="IAU67_RS09285"
                     /old_locus_tag="IAU67_09285"
     CDS             complement(317..520)
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013241084.1"
                     /locus_tag="IAU67_RS09285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IAU67_09285"
                     /product="cold-shock protein"
                     /protein_id="WP_151842910.1"
                     /transl_table=11
                     /translation="MAQGTVKWFNAEKGFGFIAPDDGSHDVFVHYSEIQGGGFRSLEED
                     QRVEFEVGAGSKGPQAQSVTAL"
     gene            711..3035
                     /locus_tag="IAU67_RS09290"
                     /old_locus_tag="IAU67_09290"
     CDS             711..3035
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1122: ATP-dependent
                     RNA helicase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014010955.1"
                     /locus_tag="IAU67_RS09290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IAU67_09290"
                     /product="DEAD/DEAH box helicase"
                     /protein_id="WP_187767905.1"
                     /transl_table=11
                     /translation="MKNSTLTHVRHEPARPSQPVDWPQWAHPDLVAYLQESGIDRPWSH
                     QAQTADLAFHGQDVIVSTGTSSGKSLAYQLPILSVLGQKNSTATALYISPTKALAQDQR
                     ASIARLCRGAHDVTEAVGVGKKGNGEAQEADDLGRIMVATYDGDTPQDSRRVIREQARI
                     IVTNPDMLHASIVGRPQAWTRLLKTVRFIVIDECHVYRGVFGAHVSMVLRRLLRLAHAQ
                     PTVILASATSVDPAAHARRLTGRTAISAVTEDGAPSGERTIALWEPGLLPNKKGEHGAP
                     VRRAANTESAEIMGRIIAQGARTLSFVRSRRGAEHVAMGAAEQLSSLGRSQDAVRVAAY
                     RAGYTPEDRRDLERRLDNGELLGVASTNALELGIDVGGLDVVVTSGFPGTVASFRQQAG
                     RAGRRGQGALVVLVGADDPMDTYLVHHPEALLDRPVENTVFDPSNPYVLADHLVCAAAE
                     KPLAWEEIEAWGATRVAEFLLRKGQLRRRPRGIFADLEAAKSIHGSVSIRGGAAKQVAI
                     VDSSTGRLLGTVDSTRAISDVHTGAVYVHQAETYVVEQLDLQENVAWVKESMPEYSTSV
                     NKETDIRVLTTRSTIKLDEGVWLADVDVEVSHQVTSYRKRLPDGEVLDVVPLDVPPESL
                     RTRAVAYTIDPCVLEDLGLPEPVWPGTLHAAEHAAIGLLPLMATCDRWDIGGVSTVLHA
                     DTGLPTVFVYDGYTGGAGFAEQGFRKFSSWIRATRDAVAACECESGCPSCVQSPKCGNG
                     NDPLFKRGALVLLSYLADVAE"
     CDS             complement(3130..3351)
                     /gene="allorf_2072629_2072850"
                     /locus_tag="allorf_2072629_2072850"
                     /protein_id="allorf_2072629_2072850"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MCCLCSLPGSVSRLDQLWCHNLASLFWGRDIFCQNAGFYETNQAA
                     LRILINLHRHGPGLSHLLTRSKTWEASA"
     CDS_motif       complement(3268..3351)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MCCLCSLPGSVSRLDQLWCHNLASLFWG"
                     /locus_tag="allorf_2072629_2072850_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(3130..3267)
                     /prepeptide="core"
                     /locus_tag="allorf_2072629_2072850_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.30"
                     /molecular_weight="4999.6"
                     /monoisotopic_mass="4996.6"
                     /core_sequence="RDIFCQNAGFYETNQAALRILINLHRHGPGLSHLLTRSKTWEA
                     SA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MCCLCSLPGSVSRLDQLWCHNLASLFWG"
                     /leader_location="[3267:3351](-)"
                     /alternative_weights="5017.6"
                     /alternative_weights="5035.6"
                     /alternative_weights="5053.7"
                     /alternative_weights="5071.7"
                     /alternative_weights="5089.7"
     CDS             3780..3842
                     /gene="allorf_2073279_2073341"
                     /locus_tag="allorf_2073279_2073341"
                     /protein_id="allorf_2073279_2073341"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MADITYARTRQGIRIRRFCH"
     CDS_motif       3780..3800
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MADITYA"
                     /locus_tag="allorf_2073279_2073341_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       3801..3842
                     /prepeptide="core"
                     /locus_tag="allorf_2073279_2073341_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.40"
                     /molecular_weight="1681.0"
                     /monoisotopic_mass="1679.9"
                     /core_sequence="RTRQGIRIRRFCH"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MADITYA"
                     /leader_location="[3779:3800](+)"
     gene            complement(4002..4214)
                     /locus_tag="IAU67_RS10055"
                     /old_locus_tag="IAU67_09295"
     CDS             complement(4002..4214)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013068.4"
                     /locus_tag="IAU67_RS10055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IAU67_09295"
                     /product="transposase"
                     /protein_id="WP_342355624.1"
                     /transl_table=11
                     /translation="MTCLGFMCKIHAGLMILAAVRQVLPAPSWQRCRTHFAKNPSLKVL
                     KYQWTAPSVKIRRWRQQFHIRKTSG"
     CDS_motif       complement(4176..4214)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTCLGFMCKIHAG"
                     /locus_tag="IAU67_RS10055_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(4002..4175)
                     /prepeptide="core"
                     /locus_tag="IAU67_RS10055_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.50"
                     /molecular_weight="6659.9"
                     /monoisotopic_mass="6655.8"
                     /core_sequence="LMILAAVRQVLPAPSWQRCRTHFAKNPSLKVLKYQWTAPSVKI
                     RRWRQQFHIRKTSG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTCLGFMCKIHAG"
                     /leader_location="[4175:4214](-)"
                     /alternative_weights="6677.9"
                     /alternative_weights="6695.9"
                     /alternative_weights="6713.9"
                     /alternative_weights="6731.9"
                     /alternative_weights="6750.0"
                     /alternative_weights="6768.0"
     misc_feature    complement(4336..4350)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
     misc_feature    4340..4354
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
     CDS             4638..4763
                     /gene="allorf_2074137_2074262"
                     /locus_tag="allorf_2074137_2074262"
                     /protein_id="allorf_2074137_2074262"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MATGTADIAQPALWGAALGGAAGSAAGAAASAFWWGVGSPC"
     CDS_motif       4638..4718
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MATGTADIAQPALWGAALGGAAGSAAG"
                     /locus_tag="allorf_2074137_2074262_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       4719..4763
                     /prepeptide="core"
                     /locus_tag="allorf_2074137_2074262_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.90"
                     /molecular_weight="1373.5"
                     /monoisotopic_mass="1372.6"
                     /core_sequence="AAASAFWWGVGSPC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MATGTADIAQPALWGAALGGAAGSAAG"
                     /leader_location="[4637:4718](+)"
                     /alternative_weights="1391.5"
     gene            4818..5099
                     /locus_tag="IAU67_RS09300"
                     /old_locus_tag="IAU67_09300"
     CDS             4818..5099
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IAU67_RS09300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="IAU67_09300"
                     /product="hypothetical protein"
                     /protein_id="WP_151842907.1"
                     /transl_table=11
                     /translation="MSKTKIRHVLHPMLGLWIASIVLLISSGSLKFDNGVIPALLIASG
                     STGILSALYVDYLAGKHGKKESINATLLTITGIEAEPCFYVLIGSLTM"
     gene            complement(5230..5685)
                     /locus_tag="IAU67_RS10005"
     CDS             complement(5230..5685)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /locus_tag="IAU67_RS10005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="IS30 family transposase"
                     /protein_id="WP_225723577.1"
                     /transl_table=11
                     /translation="MGKDNHSAVITLVERVSRFAGLGHLPGRHTSDEVLAALEATVARM
                     DRAIWPSITWGQESEMSGHNTFTRVTDMPIYFCYPGSPWERETNENTKGRLRRNLPEST
                     DLSAYSSEDLKIIANIHNHTLRKALGWITPAKVMAQALKQTGSIKSN"
     misc_feature    complement(5753..5768)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.19"
                     /tool="antismash"
     gene            complement(5877..6509)
                     /locus_tag="IAU67_RS10010"
     CDS             complement(5877..6509)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IAU67_RS10010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_225723576.1"
                     /transl_table=11
                     /translation="MDYLQLRLASLSPQEAFRAAGACLDPGAVSDFERGVKMVGGSRRE
                     FIAQGSDAATYNRLMTALRERTEVIEPGRLLPPALPRGVDPYKPISRWYLSFEELVVIA
                     EMLRDNASSHHIGWILGHSASFIQREVARNHSADGPYRAETVRLKAYVRRLCPELAKLV
                     SNHRLQTYVIDGLRAQWSSEQFSHRLLIDYSDEKDMSIRHETIYGAF"
     CDS             complement(6739..6855)
                     /gene="allorf_2076238_2076354"
                     /locus_tag="allorf_2076238_2076354"
                     /protein_id="allorf_2076238_2076354"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MVRFIPCQRPSSSCLPYLLVGVVCDHRHASWGATITTC"
     CDS_motif       complement(6757..6855)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MVRFIPCQRPSSSCLPYLLVGVVCDHRHASWGA"
                     /locus_tag="allorf_2076238_2076354_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(6739..6756)
                     /prepeptide="core"
                     /locus_tag="allorf_2076238_2076354_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.10"
                     /molecular_weight="483.6"
                     /monoisotopic_mass="483.2"
                     /core_sequence="TITTC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVRFIPCQRPSSSCLPYLLVGVVCDHRHASWGA"
                     /leader_location="[6756:6855](-)"
                     /alternative_weights="501.6"
                     /alternative_weights="519.6"
     gene            <6896..7117
                     /locus_tag="IAU67_RS09310"
                     /old_locus_tag="IAU67_09310"
                     /pseudo=""
     CDS             <6896..7117
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011113078.1"
                     /locus_tag="IAU67_RS09310"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="IAU67_09310"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="PSEPKRNREIHRRTDVVTTVPNRDAVVRLIGAVLAEQQDDWVQHK
                     RYMSLTSPAHTRDTNITGVIDNRRPNGK"
     CDS             complement(7271..7384)
                     /gene="allorf_2076770_2076883"
                     /locus_tag="allorf_2076770_2076883"
                     /protein_id="allorf_2076770_2076883"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MLPGEGDLQHQGNGTAFGSVPIWVLQVGCRTSSQARR"
     CDS_motif       complement(7328..7384)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MLPGEGDLQHQGNGTAFGS"
                     /locus_tag="allorf_2076770_2076883_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(7271..7327)
                     /prepeptide="core"
                     /locus_tag="allorf_2076770_2076883_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.00"
                     /molecular_weight="2002.3"
                     /monoisotopic_mass="2001.1"
                     /core_sequence="VPIWVLQVGCRTSSQARR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MLPGEGDLQHQGNGTAFGS"
                     /leader_location="[7327:7384](-)"
                     /alternative_weights="2020.4"
                     /alternative_weights="2038.4"
     misc_feature    7996..8010
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 20.41"
                     /tool="antismash"
     CDS             complement(7999..8235)
                     /gene="allorf_2077498_2077734"
                     /locus_tag="allorf_2077498_2077734"
                     /protein_id="allorf_2077498_2077734"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MLCLRRTARLHQRISEVHCQQDLTQPIPLIMFRSEITTEHFSNHQ
                     WGCTSHTRSLDVRSPYSVPPKRIVLDYYVPISK"
     CDS_motif       complement(8110..8235)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MLCLRRTARLHQRISEVHCQQDLTQPIPLIMFRSEITTEHFS"
                     /locus_tag="allorf_2077498_2077734_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(7999..8109)
                     /prepeptide="core"
                     /locus_tag="allorf_2077498_2077734_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.50"
                     /molecular_weight="4074.6"
                     /monoisotopic_mass="4072.2"
                     /core_sequence="NHQWGCTSHTRSLDVRSPYSVPPKRIVLDYYVPISK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MLCLRRTARLHQRISEVHCQQDLTQPIPLIMFRSEITTEHF
                     S"
                     /leader_location="[8109:8235](-)"
                     /alternative_weights="4092.6"
                     /alternative_weights="4110.6"
                     /alternative_weights="4128.7"
                     /alternative_weights="4146.7"
                     /alternative_weights="4164.7"
                     /alternative_weights="4182.7"
     CDS             8200..8352
                     /gene="allorf_2077699_2077851"
                     /locus_tag="allorf_2077699_2077851"
                     /protein_id="allorf_2077699_2077851"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MVEPRCAAEAEHGCKKWLMAPLGARPVSRVLGSALLSGLRPLTWC
                     ICIPW"
     CDS_motif       8200..8271
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MVEPRCAAEAEHGCKKWLMAPLGA"
                     /locus_tag="allorf_2077699_2077851_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       8272..8352
                     /prepeptide="core"
                     /locus_tag="allorf_2077699_2077851_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.50"
                     /molecular_weight="2822.4"
                     /monoisotopic_mass="2820.6"
                     /core_sequence="RPVSRVLGSALLSGLRPLTWCICIPW"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVEPRCAAEAEHGCKKWLMAPLGA"
                     /leader_location="[8199:8271](+)"
                     /alternative_weights="2840.4"
                     /alternative_weights="2858.5"
     gene            8411..9347
                     /locus_tag="IAU67_RS09315"
                     /old_locus_tag="IAU67_09315"
                     /pseudo=""
     CDS             8411..9347
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018582092.1"
                     /locus_tag="IAU67_RS09315"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="IAU67_09315"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLTQAPVLMCQMLRDFIN"
     gene            9500..9682
                     /locus_tag="IAU67_RS09320"
                     /old_locus_tag="IAU67_09320"
     CDS             9500..9682
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_ha"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF000539.0"
                     /locus_tag="IAU67_RS09320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IAU67_09320"
                     /product="plantaricin C family lantibiotic"
                     /protein_id="WP_151842906.1"
                     /sec_met_domain="mature_ha (E-value: 2.7e-06, bitscore:
                     23.9, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKNAGIFEEISDQYVPEANAAGQGWGTLVTSLNCYGASWALGNE
                     GNFCTGTIECQKTCQ"
     CDS_motif       9500..9613
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MVKNAGIFEEISDQYVPEANAAGQGWGTLVTSLNCYGA"
                     /locus_tag="IAU67_RS09320_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9614..9682
                     /prepeptide="core"
                     /locus_tag="IAU67_RS09320_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.30"
                     /molecular_weight="2318.5"
                     /monoisotopic_mass="2317.0"
                     /core_sequence="SWALGNEGNFCTGTIECQKTCQ"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVKNAGIFEEISDQYVPEANAAGQGWGTLVTSLNCYGA"
                     /leader_location="[9499:9613](+)"
                     /alternative_weights="2336.6"
     gene            9733..9933
                     /locus_tag="IAU67_RS09325"
                     /old_locus_tag="IAU67_09325"
     CDS             9733..9933
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IAU67_RS09325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="IAU67_09325"
                     /product="hypothetical protein"
                     /protein_id="WP_187767907.1"
                     /transl_table=11
                     /translation="MHNYSASNGFISDEAMLQIIDANDASLSNQVAAGTTSPLCVVGGA
                     VSAASAYLDDACPTSGCTHSC"
     CDS_motif       9733..9882
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MHNYSASNGFISDEAMLQIIDANDASLSNQVAAGTTSPLCVVGGAVSAAS"
                     /locus_tag="IAU67_RS09325_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9883..9933
                     /prepeptide="core"
                     /locus_tag="IAU67_RS09325_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.40"
                     /molecular_weight="1571.7"
                     /monoisotopic_mass="1570.6"
                     /core_sequence="AYLDDACPTSGCTHSC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MHNYSASNGFISDEAMLQIIDANDASLSNQVAAGTTSPLCV
                     VGGAVSAAS"
                     /leader_location="[9732:9882](+)"
                     /alternative_weights="1589.7"
     gene            10001..12973
                     /locus_tag="IAU67_RS09330"
                     /old_locus_tag="IAU67_09330"
     CDS             10001..12973
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024964.4"
                     /locus_tag="IAU67_RS09330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IAU67_09330"
                     /product="DUF4135 domain-containing protein"
                     /protein_id="WP_187767908.1"
                     /sec_met_domain="DUF4135 (E-value: 2.2e-58, bitscore:
                     195.1, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.4e-14, bitscore:
                     49.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTFLKKSISVASKRFISQLTDDHAGEFHGLFPHYLRPFLEQGAYS
                     LEAYARDTGRELGENIICNALRLLARRHKDLAIRSLITHFQYLRETSTQNDSAFSTSSQ
                     DGIPWDYAVYNIDIEQGSARDDLFSHVPLLDSLTATCQQHWFEYIVRVLDSVHADYSEL
                     QKHFHVGGKLHAIEFGLGDPHRGGISVAICQWEIGDKVVLKFTEHTPAGLVRELLQSLD
                     PHQEFFGPVLPFQWSPPERERQWQRYVEQEQFTADQAREYFRRYGRCSALILALGGNDF
                     HRENVISTVAGPTFVDTETLTSLPSATSETSDNIYEKTAAYESYSVLRTLLFPVQFAGS
                     PVAEELSAIGVPTRAARSIQSITICSRGTNDIRFDESAVTVKPTNNTVCDGAGNQFDPR
                     AFLPSIVEGFAEAFLHLQQHRDVLPQTLRSCPPFGIRHVPRPTWIYAKLLGTSTHPSRL
                     GHEDARQHTLELLPNVDPQRMGEDLSRTMRCEEIAALTQLDIPYFWIAAEGTVFGRDSA
                     RPLGSFPKTPAQCLQHWWDKVLNSDVRIHIRRIKLSLSAVGNDPYEKADIVYRHEDVSV
                     PTPLPEHVTGIQNGQTSISWLTTHQISGKVQLNLISPSLYEGGGVLLSFLSDRRQLVDT
                     TTKSHVVMDALRGAILHDMPEAPGDLHDMLYSAFGGIPGELATEMELAAIGMTGTEKGD
                     LRYPEEMQVLLTQLPDLLERYENPGSQDYLNGLSGTFTAMNQFRDLLNLQSVGKQWAER
                     TGEIHTHLENALCSMESMRDEALGLAHGRSGQVLGIVELLDLLMRAGVEIPENFLNRAL
                     ALSTSLPDRLAEDKAMIDLSAAHSWCKGRAGMVMALSRVMSIASEWEKKTAIAGLKISG
                     GWIDDWAEHNARFLLPTAQQFCRSGDISFCHGAAGGVLNWHIIGAATGSQASTELAETY
                     YTEFQKVAATNGWRTGLYSSPHAEGFFVGRAGWDLATAAFEGHATFIPRMISLSVGRRC
                     A"
     misc_feature    10006..10019
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 19.21"
                     /tool="antismash"
     gene            12970..15171
                     /locus_tag="IAU67_RS09335"
                     /old_locus_tag="IAU67_09335"
     CDS             12970..15171
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="IAU67_RS09335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IAU67_09335"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_187767909.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.5e-30, bitscore:
                     102.6, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHAPQSTSTFKPARRKPPVILQLAQSECGLCSAAMILEYWGYRG
                     AIYEMRRNTDPGRDGLGLKDVASMLTERGINVNFVQANFQGLQRVNEPFIAFWKGYHLV
                     LVEKLNEQRAIILDPASGRARISAEEFEESFSGHALLCTPTKHFAPQRERGYSIRTIWR
                     ELTTRSYMGSGAKILLLSLLLYVFTLGIPIVTKELVDRKNELIDGYSTVAIALVLILPF
                     VIYSLFGILRTRILATMIAHVGEDLMGGVFKKLLSLPYRFFASRPNGELMMRLSSVNQL
                     RDLVSNQITAVLLDVGVVIFIVGYLVFAIPCLSIVAIGLSAIMVLLTVGTWSQVQRVTD
                     EEIRALGKSTGTQMEAITAISSVKTTGMAPSFYTRWRKDYQGALHSGRRRMLVQGTVAT
                     IIGAIQMFGPFLVLAVGIKLLLKGTGTLGEVVAAQSLATMLLASVSSLSLAISQFVKAQ
                     VQIARLIDVMTHESDNTWGSEVCELSGQMTVDQLSFTYPGAQLPALSNINFSVSPGEKV
                     AVVGRTGSGKSTLAKVLVGLFPPSTGSITLDGRHSSELSEESFRKAVAYVPQDIQLSNR
                     QIAENIDFTGGTPDLELVRTAAQIAQISGTIESMPLGYHTEIQEMGANISGGQRQRIAI
                     ARAIARQPKMIVLDEATSALDNMTERNVAQSLAELNSAQIVIAHRTSTIRSADRILVLR
                     EGHLVQEGTFSELMAEDGEFRELMSSTKDLNATRQEMQR"
     gene            15254..15988
                     /locus_tag="IAU67_RS09340"
                     /old_locus_tag="IAU67_09340"
     CDS             15254..15988
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="IAU67_RS09340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IAU67_09340"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_151842903.1"
                     /transl_table=11
                     /translation="MIEVKNLEKTLGKEKILRGVSFSAPAGKITGFLGPNGSGKTTTFK
                     VMLNLMRPDNADATVTFAGEKLSSFPLSLTHVGTSMDINAMDKHRKGIDHLRSLAPLAQ
                     CSEARVNELMEEFGLGHAKNKRSGSYSMGMKQRLSLATALLGDPDFLVLDEPTNGLDPE
                     GIAWIRNYLRALAGHGKTVVISSHLLNEAQKFIDYVVIIKQGRIAYEGDISQLHALCEQ
                     RTGRKVTDLEEAYRVVTAKEEN"
     misc_feature    complement(15261..15277)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 20.22"
                     /tool="antismash"
     gene            15991..16764
                     /locus_tag="IAU67_RS09345"
                     /old_locus_tag="IAU67_09345"
     CDS             15991..16764
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IAU67_RS09345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="IAU67_09345"
                     /product="hypothetical protein"
                     /protein_id="WP_151842902.1"
                     /transl_table=11
                     /translation="MLGPQLISEWKKATTSITWWAVGALIVTANVLVTSFFTFVGLNVE
                     RSPIDATAPDSVRMFLTVGVAFTFILPLILGMLIVNLEFYNNTIIYSFLGNQRRGSLYL
                     AKLVTCAVSAMLFSVLFALMSLAVVAGLLSSSSKPATVFTGQTWGTLLSIVVISTLLGV
                     IGGALGALVTKPMLAIVLIILWSQVIEPILRIASPTKAQGYLPSSLIDASLGGGFLGQM
                     FNSEQLSQPLALGILAAVTVVLGILGGVKYAHQEV"
     gene            16770..19862
                     /gene="lanM"
                     /locus_tag="IAU67_RS09350"
                     /old_locus_tag="IAU67_09350"
     CDS             16770..19862
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lanM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="IAU67_RS09350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IAU67_09350"
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="WP_151842901.1"
                     /sec_met_domain="DUF4135 (E-value: 1.4e-52, bitscore:
                     176.0, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 6e-37, bitscore:
                     124.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKQKEPIDTAIATFLPELQNETKRQTVRELIEEFAECTPWYRYQ
                     YTQSTNATSLEQDRRDPQVQPSLADLMRAIRNMNISEHPSQDDPRFIEWFLELTRSWTA
                     LLNSPWQAALRFPPSQRLTHSIEMDLLQVIETQLFRCVADSLEKRRMAGDLSGVSSAER
                     FDDFYRWLSSAEGCEHFEENYGGQVVQAFHQLRFRCDAWCELLVRLNIDLDQINAHFFA
                     GVDLRSLLPQLQVQMGAGDSHCRGRAVAIVNLGDHRFVYKPRDLSVDQSLKFFFDELRE
                     WTGIQVSVPSVIVARGYGWAEFVTGASGDVDFQHYGRALGFLASIEFLAGGIDFHYENV
                     VGTADSGVSIIDAETCVGASPVNKKTYASGSGSMVGAQKVFHSVISTGLLPLPQVVPGR
                     IGIIDVGATGITEGETTSPFKSLLAKNPGSDLMHIAFENLPYRSENSNPQPRTTVAGVV
                     EFRDQIVGGVREGLEFAKANKEELCGLFERAFSGQSFRFINTPTQTYSQLLRMVTSPGV
                     VNDPVAHVAVLSRCEMFSDREKSAAAFEVEQMLDGDVPYFQISFGDNCLYGMEGEPLID
                     GFFEGSPKETIFRRIHELDDESINEQVDLCMAAFARSLPVGAEGTPALGEAPECSVDVD
                     VALQTGAELILARGCRSDNDRQPSTFWGPQISVEDSTQWTLGTAGYDLYGGSPGVALAL
                     SASERRLRTGKYGEFAETVFGPISHQILDDLINDGTYGIGGYMGVAGTLWAAVWDRRLR
                     GLNYGDIAVESLNKLSQNIEGKTSADFVVGQSGALAVAVNLARMCSDIGIDVSGIMETI
                     VSYSLPVLEKDFREGWIGTSESTPYSGFAHGLAGSMASIAAATTVLSPQSSLKAQAEKV
                     VQEMIDALEGVVDNTGAVTRSKTDQRKDAAWCHGSPGVLLGFTIAWENGFRTDPEVLHN
                     LAQYVRRRGVGNNSTVCHGDLGSLRVLKRYAELVDDEALAASIHKEIVNRSKYIAVRKR
                     TDYQDKYSSTDSLMLGRAGAILTLLHELDPREYPDVTSLGI"
     gene            <19924..>20040
                     /locus_tag="IAU67_RS10015"
                     /pseudo=""
     CDS             19924..>20040
                     /GO_component="GO:0005840 - ribosome [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003940951.1"
                     /locus_tag="IAU67_RS10015"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="uL14 family ribosomal protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRTNKGAAVIITANNNDPLNTRIFDPVTRELREKKFVKI"
     gene            20158..21516
                     /locus_tag="IAU67_RS09360"
                     /old_locus_tag="IAU67_09360"
     CDS             20158..21516
                     /GO_function="GO:0004806 - triglyceride lipase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016042 - lipid catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012361086.1"
                     /locus_tag="IAU67_RS09360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IAU67_09360"
                     /product="lipase family protein"
                     /protein_id="WP_151842942.1"
                     /transl_table=11
                     /translation="MISFSLRRRGSRIATSLAAASVLFTGVAVPGVVSPPSAQAQSSEF
                     FGSIADITPGSLVKSTPAMADVRPYSKPTADSGLRIPNASEAQGRTGVPLGEVDLDPMV
                     GLAQAAVQKRFVYSTTNQHGEVATSTGTVFLPAGPAPEGGWPVLAWAHGTVGLGDQCAP
                     SINQRSPRDAEYLNHWLSQGYAIVATDYAGQGTPGLMSYLNGQAEADSVVDSVIAARAL
                     GSMAKDGSSLLSHRWAVIGQSQGGGAALQVARLATQRSTPAGLDFRGTVATGAPAYVEE
                     IVAAGGPTFPPVTLPTGLNVYALYILAALREARPDIDVNSALNEQGRRMVDAAETACLG
                     ELSEAMKGVNIAHGFSKPLRSVPGLVDAARSMMATPAYGYDRPVFVGHGLKDMDVPTPI
                     GLLLNTDMWFQQFNLDAHARNTRVEVRWYPTNHGDTVFASVPDSTPFLRSIFN"
     gene            complement(21513..21902)
                     /locus_tag="IAU67_RS09365"
                     /old_locus_tag="IAU67_09365"
     CDS             complement(21513..21902)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03816.1"
                     /locus_tag="IAU67_RS09365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IAU67_09365"
                     /product="Rv3654c family TadE-like protein"
                     /protein_id="WP_151842900.1"
                     /transl_table=11
                     /translation="MSTTYGASIILGLIALSIGIISGVKLLSAAQETQLAADMTAIAAA
                     TALATGDTEDPCATASAFADQNHATLEACEVIGEDVRVEVSRWGRTASAVAGPSEPSDP
                     SEPSDPSAPGGPGEPGSIVPDAPAR"
     gene            complement(21899..22252)
                     /locus_tag="IAU67_RS09370"
                     /old_locus_tag="IAU67_09370"
     CDS             complement(21899..22252)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011274242.1"
                     /locus_tag="IAU67_RS09370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IAU67_09370"
                     /product="hypothetical protein"
                     /protein_id="WP_151842899.1"
                     /transl_table=11
                     /translation="MNTIEGAVVLSALTLTAGTLVGGFITLAQHAAVTSLARDAARAEA
                     LGHNGSAVVAARSPDARVTVSATTVGDLEAVRVQVTRHAALFDVHGEAVTITEPRAAEP
                     DGDLPRELEGPAR"
     misc_feature    22254..22266
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.92"
                     /tool="antismash"
     gene            complement(22273..22467)
                     /locus_tag="IAU67_RS09375"
                     /old_locus_tag="IAU67_09375"
     CDS             complement(22273..22467)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019510766.1"
                     /locus_tag="IAU67_RS09375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IAU67_09375"
                     /product="DUF4244 domain-containing protein"
                     /protein_id="WP_151842941.1"
                     /transl_table=11
                     /translation="MWARALKACRDHIDDEGGMSTIEYALGCVAAAALGALLYTVVTSG
                     AVEDALRGIFERALNEGGK"
     CDS_motif       complement(22393..22467)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MWARALKACRDHIDDEGGMSTIEYA"
                     /locus_tag="IAU67_RS09375_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(22273..22392)
                     /prepeptide="core"
                     /locus_tag="IAU67_RS09375_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-1.50"
                     /molecular_weight="3823.4"
                     /monoisotopic_mass="3821.1"
                     /core_sequence="LGCVAAAALGALLYTVVTSGAVEDALRGIFERALNEGGK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MWARALKACRDHIDDEGGMSTIEYA"
                     /leader_location="[22392:22467](-)"
                     /alternative_weights="3841.4"
                     /alternative_weights="3859.4"
     CDS             22526..22690
                     /gene="allorf_2092025_2092189"
                     /locus_tag="allorf_2092025_2092189"
                     /protein_id="allorf_2092025_2092189"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGSAEIGSASAVLLTTGSARAGCPRAGLVMTSSVVTGSIVIDMVS
                     FLSVCVVDM"
     CDS_motif       22526..22549
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGSAEIGS"
                     /locus_tag="allorf_2092025_2092189_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       22550..22690
                     /prepeptide="core"
                     /locus_tag="allorf_2092025_2092189_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.30"
                     /molecular_weight="4375.2"
                     /monoisotopic_mass="4372.3"
                     /core_sequence="ASAVLLTTGSARAGCPRAGLVMTSSVVTGSIVIDMVSFLSVCV
                     VDM"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGSAEIGS"
                     /leader_location="[22525:22549](+)"
                     /alternative_weights="4393.2"
                     /alternative_weights="4411.2"
                     /alternative_weights="4429.2"
                     /alternative_weights="4447.3"
                     /alternative_weights="4465.3"
                     /alternative_weights="4483.3"
                     /alternative_weights="4501.3"
                     /alternative_weights="4519.3"
                     /alternative_weights="4537.4"
     gene            complement(22775..23875)
                     /locus_tag="IAU67_RS09380"
                     /old_locus_tag="IAU67_09380"
     CDS             complement(22775..23875)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012694.4"
                     /locus_tag="IAU67_RS09380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IAU67_09380"
                     /product="type II secretion system F family protein"
                     /protein_id="WP_151842898.1"
                     /transl_table=11
                     /translation="MTVLIWMFCASLWGYVGWKVGRRIVDDRGVRQGIDMLLEFARLVA
                     RDCHAGARIPTAVHAACSTMQSSERAQERGQELAHRMRTTACIHEMGGAIDPADGGGEA
                     EQRFLVLWALAAEHGIGLGDLLDTFCRDLEARLAHHSKTHSAMGGARLTVVVLLSLPPG
                     AVILGQSLGLGTVSFYTQSILGSLFGLVGTLLACAGVLWAEALTATVLGGVGRRAGPHD
                     PTGAARVLDLVAAALRAGAPLVHAWELAVSTSAFVPEEDGSHSTVRAIPALLHLGAGAS
                     AWEQLAEDPFYGPIARMAAQQSTSGAMLADAMAHHAEYLRKLSLDKATEAAEKMLVVLA
                     APLTLCFLPAFVVTGLIPLALGLAGL"
     gene            complement(23872..25083)
                     /locus_tag="IAU67_RS09385"
                     /old_locus_tag="IAU67_09385"
     CDS             complement(23872..25083)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013889353.1"
                     /locus_tag="IAU67_RS09385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IAU67_09385"
                     /product="TadA family conjugal transfer-associated ATPase"
                     /protein_id="WP_151842897.1"
                     /transl_table=11
                     /translation="MTTMSIDAVRRALAERGISHVGPEDLVEFGGHAQQDGGGEGGAGG
                     VEFLRTLHREFSGLGILTELFMDPDVTDVLVNPDGRIWIDRGEGLEPAEMPPVPPGQAR
                     ELAVRLAARCGARLDNAMPFADGVLTGLPEGIPARRLRVHAALAPPMDGGASISLRALH
                     RGHSHVEDLVRDGMMSPALGMVLRQIVRQRMNILISGGTGAGKTTLLTALLGEVPGNQR
                     MILVEDTPEIIAEHPHCLAMTARRANAEGAGDIPMGRLVTQCLRMRPDRIIVGEIRGAE
                     IADLLVALNTGHPGSAGTLHANDPQAVPGRLEALGAMADMPPRSLVRQSLDGIDVLLHV
                     ERTPQGRKLTDISTLHASHSRNGAPVLVVEPVWSIHQSSMDADDVVGRIQRQRAQCDSE
                     RSAP"
     gene            complement(25080..26333)
                     /locus_tag="IAU67_RS09390"
                     /old_locus_tag="IAU67_09390"
     CDS             complement(25080..26333)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IAU67_RS09390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="IAU67_09390"
                     /product="hypothetical protein"
                     /protein_id="WP_151842896.1"
                     /transl_table=11
                     /translation="MARHAATPQVQERGPRAAEIRTTKTRAADARPVIVDVQDAQWLEE
                     AQMIAAATGRTLLSAATPQAVERIHAALEGLDDVRSSGARRRAGGAAAILIHDRPNPLQ
                     NHPRIRAIDIAPDSTQVSRTLSQGGVLDLARLVGMHDLPLIAVYGAVGGAGTTVFSVCF
                     AHALSGDYPSVVLDASPHSLGVDIALGKEHSVSELGVRTLLECNYIQLLSRAPRIGKIP
                     IISQAGTQWQQPALLGSAACVADCGTLRPGSDDFLTIFGEASGNSRGNPSVMVPDAHVV
                     VTIATVPGLMYAKRLCDRLADHWGVDPLVVVRDFAGSDVPHSLMPVILQRYRMRTVRSD
                     AAVARALNKGEPEHFLHDGHSLVRSADSLVQEWKKDHTLLVKELLGADVPRGDDALRGD
                     DAFRDDDVARATDEGGAA"
     gene            26621..27478
                     /locus_tag="IAU67_RS09395"
                     /old_locus_tag="IAU67_09395"
     CDS             26621..27478
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013889355.1"
                     /locus_tag="IAU67_RS09395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IAU67_09395"
                     /product="HAD-IB family hydrolase"
                     /protein_id="WP_225723575.1"
                     /sec_met_domain="HAD_2 (E-value: 6.8e-06, bitscore: 23.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHPKNVTTTHPTKVLAIFDLDKTIINTSASLAYGRPLAERGLITT
                     TEVIRMIAIRSSFMLTTHDQEDLNATKEALASMIKGREAEPLKTVAREALHDVIIPYIY
                     AEAHELLEWHREQGHTIAIVTASPSVVVEPIAEELGADILIASELEVEDGLFTGNVTLF
                     NKGVTKVHHIQDIAGEHGFDLSQSYAYSDSGTDVPMLELVGHPTAVNPDRALKKVAAER
                     EWPIVNFRRPEPITQSNVAVLAGAGATLAILGAVATSVTLWLFNRDSSSSDGSGQADVT
                     PDAA"
     gene            complement(27513..28316)
                     /locus_tag="IAU67_RS09400"
                     /old_locus_tag="IAU67_09400"
     CDS             complement(27513..28316)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011274248.1"
                     /locus_tag="IAU67_RS09400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IAU67_09400"
                     /product="Fic family protein"
                     /protein_id="WP_151842894.1"
                     /transl_table=11
                     /translation="MSQKNSPTASAPDPLAPLAELPGVPEAVDKAVDYISRVHRHKANL
                     RGWDVTGSEAVLRGARASAQIDGGTPWLPEDGQVNDPILAGALRAAELLAPDGITETQT
                     TFRRAPLQVIAKINSVASPQMSDEDFRKKAAQSAEFLVPGRPRRDADGRLQLLGSFITG
                     GTKVNAVVLTAVIHGELLALQPFADANGVTARACSRLATISTGLDPRGLGVPEVWWNRH
                     RDEYEAKAKGFASGTAEGVAEWIVFHAEGLAEGTLEAKSIADAKA"
     gene            28429..28929
                     /locus_tag="IAU67_RS09405"
                     /old_locus_tag="IAU67_09405"
     CDS             28429..28929
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005323120.1"
                     /locus_tag="IAU67_RS09405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IAU67_09405"
                     /product="phage holin family protein"
                     /protein_id="WP_151842940.1"
                     /transl_table=11
                     /translation="MFTDRDSFNPTVNSIPLSDVDTRAKGQGSIGDLVKDASSQISSLV
                     RSEIELAKTEVATSAKKAGIGVGLFAAAGIILAYSSFFLFFTIAEGLDNFMPRWLAFLI
                     VFLFMIVLVAILALVGLKQVKQVKAPEKTIDSVGELKTVVPSRGGNSAAARAADHRDPG
                     MYS"
     misc_feature    complement(29248..29262)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.5"
                     /tool="antismash"
     misc_feature    complement(29400..29416)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 23.0"
                     /tool="antismash"
     misc_feature    complement(29512..29526)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.73"
                     /tool="antismash"
ORIGIN
        1 tcgcttcacc atatgggtgg ctcactcttc ctcaccgtgc ggaactgaag gatttttctt
       61 ccttatatat tgcatgcact tcacacgcac tcttggccgt cacaataacc gaaaatgcta
      121 agcaatacat tttccctcac catcgtgtta ccccgttccc ccctcgaccc ctccctccca
      181 tggtgtcctg acctgctctt tttatgattt cacgtggtgg gacacgcggg gtagctggag
      241 acatagcaac aggccacgcc caccaggatg gtggcgtggc ctgttgctcg tgtgtcctca
      301 cacgatgagc gggagactac agcgcagtca cgctctgagc ctgggggccc ttggagccag
      361 cgccgacttc aaattcaacg cgctggtctt cttcaaggga acggaaaccg ccaccctgaa
      421 tctcggagta gtgcacaaaa acgtcatgag atccatcgtc tggtgcgatg aagccgaagc
      481 ccttttctgc attgaaccat ttcacggttc cttgtgccat tatgttctta cctaactgtt
      541 ggagaatctc cgaaatccct tgcggaggtg gagacgttgt ccatcttgcc acgtttgacc
      601 gcgcaacctc tcaaccacga aggacccagg tgccagattt cagccccgct agcccacccc
      661 gtcagccttc ccactttggc gatgagctac tccaggagct acaggcacac atgaaaaact
      721 ccacgctcac gcacgttcgc cacgaaccgg cgcgcccatc ccaacccgtc gattggccac
      781 agtgggcaca tccggatctg gtggcgtacc tgcaggaatc cgggattgat cgcccgtggt
      841 cccatcaagc gcagactgcg gatctcgcgt ttcatggcca ggacgtgatc gtgtccacag
      901 gcacgtcctc cgggaagtct ttggcctacc aattgccgat tttgtccgtc ctggggcaga
      961 aaaatagcac ggccacagcg ttatatatct cacctaccaa agcactggct caggaccaac
     1021 gggcaagcat tgcgcgtctg tgccggggag cgcacgatgt tacggaggcc gtgggcgtcg
     1081 gtaaaaaagg caacggagag gcgcaggagg cggacgatct aggcagaatc atggtcgcta
     1141 cctacgacgg cgacaccccg caggacagcc ggcgcgtgat ccgcgagcaa gcgcgcatca
     1201 tcgtgacgaa cccggacatg ctgcacgcgt ccattgtggg gcggccgcag gcgtggaccc
     1261 gcctgctgaa gaccgtgcgg ttcattgtga ttgatgagtg tcacgtctat cgcggtgtgt
     1321 tcggcgcgca cgtctccatg gttcttcgcc ggttgttgcg gctggctcac gcgcaaccca
     1381 cagtgattct ggccagcgcc accagcgtgg atccggcggc gcacgcgcgc aggttaacgg
     1441 ggcggacagc gatcagcgct gtgactgaag acggagcgcc atccggtgaa cgcacgatcg
     1501 cgctatggga gccagggctg ctcccgaaca aaaagggcga gcatggcgca ccggtacgcc
     1561 gcgcggcgaa cacggaatcc gccgagatca tgggcaggat tatcgcgcag ggtgcgcgta
     1621 ctttgtcctt cgtgcgctcg cgtcgcgggg ctgagcatgt tgcgatgggg gcggcggagc
     1681 agctctcctc gttgggccga tcccaggacg cggtgcgggt ggcggcctac cgtgcgggat
     1741 acaccccgga agatcgtcgg gatctagaac ggcgcttgga caacggcgag ctgctcggcg
     1801 tggcctccac caatgcgctg gagttgggca tagatgtggg cgggttggat gttgtggtga
     1861 ccagtggttt tcctgggaca gtcgcgagct tccggcagca agcgggacgc gcggggcgca
     1921 gaggccaggg agccttagta gtgctggtag gggcagacga cccgatggac acatacctcg
     1981 tgcaccaccc agaggcgttg ctggataggc ccgtggagaa tacggtgttt gatccgtcga
     2041 acccttatgt gttggcggac catctggtgt gtgccgcggc ggaaaagcct ttagcatggg
     2101 aggagatcga ggcctggggt gctactcgag tggccgagtt tctcttgcga aaaggacagc
     2161 tccgccggcg gccgcggggc attttcgcgg acctggaggc cgcgaagagc atccatggtt
     2221 ccgtgagcat tcgcggtggg gcggcgaagc aggtggccat cgtcgatagt tccacggggc
     2281 gattgttggg gacggtggat agcacccgtg cgatcagtga tgtacacacc ggcgctgtgt
     2341 acgtgcatca ggcagaaacg tatgtggtgg agcagctaga cctgcaggag aatgtggcat
     2401 gggtcaaaga gtccatgccg gagtactcca ccagcgtgaa taaggaaacg gatattcgtg
     2461 tgctcaccac acggtcaacg atcaagctgg acgagggcgt gtggttggcg gatgtggatg
     2521 tggaggtatc ccatcaggtc acgagctatc gaaagcgact acccgatgga gaggtactag
     2581 atgtagtacc actggatgtg ccgccggaat ccctgcgtac acgtgcggtg gcttacacga
     2641 tagatccgtg tgtgcttgag gatcttggat tgcccgagcc cgtatggccg ggaacgttgc
     2701 atgccgcaga gcacgcagcg atcggtttgc tgcccctcat ggccacgtgc gatcgctggg
     2761 acattggcgg agtatccact gtgttgcatg cggacacggg attgcccaca gtgtttgtgt
     2821 atgacggcta cacaggcggg gcaggctttg cagaacaggg ctttcggaag ttctcctcat
     2881 ggattcgcgc cacacgtgat gcagtggccg cgtgtgaatg cgagtccgga tgcccgtcgt
     2941 gtgtgcaatc gcccaagtgc ggaaatggca acgatccctt gttcaagcgc ggcgcgttag
     3001 tgttgttgag ttatttggcg gacgtggctg agtaatttgg cggattggct tgccagcaat
     3061 tgttcttgct gtgattttct tgagattcca ttcttgttag gggtggcatt atcagaatct
     3121 ctttccactt caagctgaag cttcccaggt cttgcttcgc gtgagcagat gggaaaggcc
     3181 cggaccatgc cgatgaagat tgattaaaat gcggagggca gcctggttcg tctcgtagaa
     3241 gcccgcattc tggcagaaaa tatctctccc ccagaataag gatgcaagat tatgacacca
     3301 aagctggtcg agtcgtgaca cactgcccgg cagtgaacac agacagcaca atgtgatgcg
     3361 cgggtagttg caccgctacc tgaaaacttc gccgacgaaa acgccaagct acggctcaaa
     3421 aaccgggatc tgcgggacac caacgagtta ttgaaggctg cctcggcttt ttctcgcctc
     3481 agttctcggc ccacaacgtc gacaaggatc cagttcattg ataagcatct gataagcatc
     3541 agaatcgctt cacagccagg ttcatttgct cgacgctgaa gaagcgccgc caaggtggat
     3601 tctggcatgc gcttcgtcgt gaaggcaccg atatcggccg tgagcagact gtccatctga
     3661 tgcacctagc acagctaaag gtagcgcccc tgtaaccaca cgttcgtctc acggttatga
     3721 tctgcgccct gacctgatca tgcgtcagtt cacggccggg aagccgaatg catttgtgag
     3781 tggccgacat tacctatgct cgaacacgtc aagggattcg tatacgccgt ttttgccatt
     3841 gatgtgtact cctgtcgaat tttcgagtgg gcggtatctg attcgatgtc taccgagacg
     3901 ttgccgctac aaacgctgaa ccatgccatt gcctgcgcta gggaaacggc tggtctaatt
     3961 caccattgat aactacgagc cgcaatacgt cagcatcatc ttcaaccaga ggttttccta
     4021 atatgaaatt gttgcctcca ccggcgaatt ttgactgatg gggccgtcca ctggtatttc
     4081 agcactttta atgacgggtt cttggcaaag tgcgtgcggc agcgctgcca actaggagca
     4141 ggaagcactt gcctaacagc cgctaggatc atgagtccag catgaatctt gcacatgaag
     4201 cccaggcatg ttatattcat ttagtaaaca tattgattta ttacaggaac gttcctcact
     4261 tgtctaagtt gcataagttc tctttgtcga ttgctgcctc tattttaggt tttgcactac
     4321 tggcccctgt tgcgatggcc gattctatcg gccacttcga gtaatcttac agcaaagccg
     4381 ataccccctc ttccgctaag caaatcgttg aggatgaaat tactggcgat gttaatcact
     4441 tcgcaaccca gacaataatc cttaaaaatg gagtgaaagc tacggtagaa gttgatgtcg
     4501 tagcagattc tatccgagtt acgtcggaca atggcgagaa ttaccaattt aagctcagcg
     4561 aactaaaaag ttatgtacaa agtgcgggcg ccgcagagtg agttgaagct ttaagaaaga
     4621 agcctaactc atgccaggtg gcaacaggta ctgccgatat agctcaacct gccctgtggg
     4681 gagcagccct aggtggagct gcgggttctg ctgcgggagc ggcagcaagc gctttctggt
     4741 ggggtgtagg ttctccgtgt taacggaaag gttcctagac gacactaaaa gtcaaattaa
     4801 ttgtggatta tatacctatg tctaaaacaa aaataaggca cgtgttacac ccaatgctcg
     4861 gcctctggat cgcctccata gtgctcttaa tcagctctgg atctctgaag tttgataatg
     4921 gagtgatacc tgcattactg atagcctccg ggtctaccgg cattctatcc gcactatatg
     4981 ttgattatct ggcgggaaaa cacggtaaga aagaaagcat taatgctacc ctcctgacta
     5041 tcaccggaat tgaggcggaa ccatgcttct acgttttgat tggctcgctc accatgtgag
     5101 cgattgaaat gtgcggcaac gctaacttgc aagagtgaaa tttccctaat ttagtggacg
     5161 cccgattaat acggatttcc gtgtccgtga gagaggttta gattctggcg gccattgcaa
     5221 caatgacgac tagttggact tgatgctacc tgtttgtttt agcgcttggg ccatgacttt
     5281 ggcgggagtg atccatccga gtgctttgcg cagtgtgtgg ttgtgaatgt tggcgataat
     5341 cttaaggtct tctgaactat atgccgacag gtcggtactt tcgggcagat tgcgtcgtag
     5401 cctgcccttg gtattttcgt tggtttcgcg ctcccatggt gaacctggat agcagaagta
     5461 gatgggcatg tcagtgaccc tggtaaaagt gttatgacca gacatttcac tttcttgacc
     5521 ccaggtaatc gatggccaaa tagcccggtc catgcgtgcc actgttgctt ctaaagctgc
     5581 cagcacttca tcgctagtat gacgaccagg aagatgaccg aggcctgcaa accggctgac
     5641 acgctcaaca agagtgatga ctgctgaatg gttgtcctta cccacaatca ggtcaccttc
     5701 ttagtgctct ggcggggtac gttcctcaac gtcgagcggc cggtcatcga tgaggaccat
     5761 agcgtcaacg aaactctgct gagctggatc gttactgcat ggttcgcgcc tcttccgctt
     5821 tacctgtctg atggcagtgt cagaccaaat tccttcagcc accctttgga gtgcagctag
     5881 aaagcgccat agatagtttc gtgtctaata ctcatgtcct tctcatctga gtaatcgatc
     5941 aggagccgat gtgagaattg ctccgatgac cattgtgctc gtaaaccatc gatgacataa
     6001 gtttgtaacc ggtggttgga tacaagcttg gctagttcgg gacacaaccg tcggacgtat
     6061 gctttcaacc ggacagtttc agcccggtag gggccgtcag cactgtgatt gcgggccact
     6121 tcgcgttgga tgaacgaggc actgtgcccc aggatccacc cgatgtgatg agacgaggcg
     6181 ttgtcgcgta gcatctctgc gatcaccacg agctcttcaa agctgaggta ccagcgactg
     6241 atcggcttat acgggtctac gccccggggc aacgctggtg gcagtaggcg tccaggctcg
     6301 atgacttcag ttcgttcacg cagggcagtc atcagtctgt tatacgttgc tgcgtcacta
     6361 ccctgggcaa tgaattcacg tctcgaaccg cccaccatct ttactccccg ttcgaaatca
     6421 gaaacagcac cagggtcaag acaagcacca gctgctctaa acgcctcctg tggggacagg
     6481 cttgcaagcc gcagctgcag atagtccact cgccactggg tttgccgaac tctgcgttca
     6541 tagtgctgag tgtgacgtgg tcttcagcat cgcaggcaat ggcgtaagcc gctgtgggat
     6601 tcaatccact tattcctgct gtccggaaga caggcatacc tgcggacaca agcttcacaa
     6661 agtcccgagc aggctgactg caacggtcga ccggcgggtt gcgacgatat cggacaacgc
     6721 cacgggcatg gcagcaattc agcacgtggt gatggttgca ccccaactgg cgtgccgatg
     6781 atcgcacact acgcccacaa gcaagtaagg caagcagcta ctgctcggcc tttgacaagg
     6841 aatgaaacgg accacgattc tcagacaccc cctctccggg ttagtgctgc aacgaccctc
     6901 tgaacccaag agaaaccggg aaatacaccg gcgcaccgat gttgtgacca ccgtccctaa
     6961 ccgggatgct gtcgtccggc tgattggcgc tgtgctggca gaacagcaag atgactgggt
     7021 tcagcacaag cgctacatgt cgctgaccag cccggcacac accagggaca ccaacatcac
     7081 tggcgtcatc gacaaccgac gtcccaacgg gaagtagtcc gcagcatgat cgcagcccac
     7141 catcgggccc ggtccggacc ctgactccat ccctgatact gtcccggatt cagaaaggac
     7201 agatacacca ctaccccgga cttgaccgat ctgctgatca agcccctgga gaaaactgtg
     7261 gcgcttatcc tcacctgcgt gcttggctac ttgttctgca gccgacttgt agtacccaga
     7321 tcgggacact cccaaaagcc gtgccattgc cttgatgctg tagatcgcct tctcctggaa
     7381 gcatcagttc gaacttttcc gctcacgttg cttcgcagcg aagaaggcgg ctgcttttga
     7441 caaaaactca ttatccagct gagactcagc caattcccgg agcggcctgg cgttttccgc
     7501 acgcagatca gcaagactcc tatcaccatc agagcccagg cgttctcgct cgtttttgac
     7561 ctttctgcac actgcacagc agcccggcag acacgccgat ctcttcaaca acccgggtga
     7621 tcggcctttc agactcgatg accagccgag ctgcctcccg ccggacctcg ggagtgtact
     7681 ccttcctctg ctgcttactc acaatgaaca ccctctccta cggacacaaa aatccgtact
     7741 aatcgggcgt ccaccaaacg cgggtgaact caatttgctt gggaagagaa tgaacaggga
     7801 aaggaactac ggaactttgt tgtctgctag gactgcttac cttgcttata gaggaagtaa
     7861 gattgcacaa ccatgagagc gaaaatggcc cacaggaggc cagtactgtt acctcctaca
     7921 ggaaaccaag ggattgcgcc gaccagggcg acaatggcga ggacaactga gagggccagc
     7981 cagaggatgc ggagcttatt attttgaaat tggaacatag tagtcgagaa caattctttt
     8041 cgggggtaca gaatacgggg accgtacgtc gaggctacgc gtgtgcgagg tacagcccca
     8101 ctggtgattt gagaaatgct cagtagttat ttcacttctg aacattatca gaggaatggg
     8161 ctgtgtcaag tcttgttgac aatgaacctc tgatattcgt tggtggagcc tcgctgtgcg
     8221 gcggaggcag agcatggctg caagaagtgg ttaatggcac ccttgggggc gagaccggtg
     8281 tccagagttc ttggatctgc gctactcagc gggttgcgtc cgctaacgtg gtgcatctgt
     8341 atcccatggt aagccgccct ccggcgttca caggcgacca tcataggatc ccaccgccta
     8401 tctcgaagag ttgctcaccc aagcccccgt cctgatgtgc cagatgcttc gagacttcat
     8461 caactaggtc ctgtcgaccc aagccgacag catctgtggc gctaactacg ccaccgtctc
     8521 cccttaagcg gcccaacagg tgcaacggct accgaacccg ctcgctagat tccggcccgt
     8581 actattacct gtcttgtgat gcgttgacta cgaaagtgcg tgaaggtggt cgtgtggtga
     8641 acaccagcgt gcgtgttgct accggcgtta acaatgatgg ctaccgcgaa cttttgggta
     8701 tgcaggtagc cacatcagga tccgtggaat cctggacagg gttcttctaa gacctgaaag
     8761 cccgttgcct gggcaatgtg cacctggtga ccagtgatgc ctacctatgg atccaaacta
     8821 ctgttgggca cgtgcttctc actgctagct ggcagctctg ccgcgcgcat gtcgccaagg
     8881 acctgtcatc aacagcgtcg aaatgctagt ggacaaccct gtcaggaatg tttcactcca
     8941 tcgtcctcac taagccaacg tgcaggctac ctgagattag gccaggtagg tcgttgaatg
     9001 cttgtaacga ccgtttcccg gaggtagcag actctctgga ggcgtcattg gatgagatcc
     9061 tcgcattcac acatgcgccg aaagttgtgt aggcaaaaat gttgtcgaat aaccccacag
     9121 aacggctgaa caggaatatt cgccgacgcg ctgacgttgt gggcattttc cctcatcggg
     9181 atgctgttgt ccggctggtt agtgccgtgg gggcagaaca gcatgatgac tatgctcgac
     9241 acaagcgtta cgtgtcacta gctagcttgg aacacatccg aaatctcata gcctccaaca
     9301 ccatcaatac cagcaagact gacgtcatcg aggaagtcac ctcataaact acaaccccgc
     9361 ccggggcgga ccctaacccc agccttaaca ctgtcccgga ttcaggaagg gcaggaacac
     9421 cacgccccgg acttgcccca tctaataagt gagggtagcc ttagattacc ttttacgttt
     9481 gagttcagag aggataccaa tggttaaaaa cgctggaatt tttgaagaga tttccgacca
     9541 gtacgtacct gaggctaacg ccgctggcca aggctgggga accctagtca cctcgctcaa
     9601 ctgctatggc gcaagctggg cgctcggcaa cgagggcaac ttctgcaccg gcaccattga
     9661 gtgccagaag acctgccagt aaaaaccggc aaagaccacc aaatccacaa tcgcaaggga
     9721 aaggcttcca ccatgcataa ctactccgca tccaacggct tcatctctga cgaggctatg
     9781 ctccagatca tcgacgccaa cgatgcgtcc ctgtccaacc aggttgccgc tggcacaacc
     9841 tccccactgt gtgtcgtcgg tggcgcagtc agtgctgcat ctgcgtacct ggatgatgca
     9901 tgcccaacca gcggctgcac ccattcctgc taaagcagta gcccaattcc ccgcggcagt
     9961 gctcacacac ggcagtgggg ctttcctcat ttatataccg atgacattcc ttaaaaaaag
    10021 tatttctgtc gcctctaaac gctttattag ccagttgacc gatgatcacg caggtgaatt
    10081 tcatgggctt ttcccccatt atttgcgacc tttccttgaa cagggagctt attccctcga
    10141 ggcttacgct cgcgacaccg gacgtgaact gggcgagaat atcatctgca atgcgctacg
    10201 cttactagca cgccgccaca aggaccttgc gatccgcagt ctcattaccc atttccagta
    10261 tctgcgggaa acttctacac agaacgacag cgcgttctct acctcttcgc aagatggaat
    10321 tccgtgggac tatgcggtgt acaacataga cattgagcag ggctcggccc gcgacgacct
    10381 ctttagccac gtacctcttc tagattccct gaccgctacg tgccaacagc attggtttga
    10441 gtatatcgtt cgcgtcctag actctgtgca tgcggactac tcggagctac agaaacattt
    10501 ccacgtcggc ggaaagctac acgccatcga attcggcttg ggtgatcctc accgtggtgg
    10561 catatccgtc gcgatctgcc agtgggaaat tggcgacaag gtagtgctaa agttcaccga
    10621 acataccccg gccggtcttg tgagagagct gcttcaatcg ctcgacccac atcaagagtt
    10681 ctttggtccc gtcctcccct ttcaatggag cccaccggag cgagaacgcc agtggcagcg
    10741 ctatgttgag caggagcagt tcactgcaga ccaggcacgt gagtactttc gccgttacgg
    10801 tcgctgctcg gctctcattc tcgcactggg cggcaatgac tttcatcgag aaaacgtcat
    10861 cagcacagta gctgggccaa cattcgtcga tacagaaacg ctgacgagtt taccctcggc
    10921 aacctcggaa acatctgaca atatctacga aaagactgcc gcatacgagt cctacagcgt
    10981 tctacgtact ctgcttttcc cagtgcaatt cgcaggttcc cctgtggcgg aggagctttc
    11041 cgctattggg gtccccacta gagccgctcg ttcgattcaa tccatcacga tctgttcccg
    11101 cggaactaac gatattcggt ttgatgagtc cgcggtcacc gtgaaaccaa ccaacaacac
    11161 tgtgtgtgac ggtgcgggca atcagttcga tccacgagct tttctcccca gcatcgtcga
    11221 aggtttcgcg gaggcgttcc tccatctgca gcagcatcgg gatgttttgc cgcaaacgct
    11281 ccgcagctgc cctccttttg ggatccgcca tgtccctcgc cccacctgga tatatgccaa
    11341 gctactcgga acttccactc acccctcccg tctgggccat gaggatgcgc gacagcacac
    11401 tcttgagctg ttgccgaatg ttgatcccca gcgcatgggc gaagatcttt cccgcaccat
    11461 gcgttgtgaa gagatcgctg ccctgacaca actagatatt ccgtatttct ggatcgctgc
    11521 ggagggaacg gtattcggtc gtgattctgc tcgtcctttg ggcagctttc ccaaaacccc
    11581 ggcccagtgt ctacagcact ggtgggataa ggtgctgaat tctgacgtga gaattcacat
    11641 tcgccgcata aagctgtctt tgtctgcggt gggcaatgac ccgtatgaaa aagcagatat
    11701 tgtctaccgt cacgaggatg tgtctgttcc tactcctttg cccgagcatg taacgggtat
    11761 tcaaaacggt cagacgagca tcagctggct taccacacat cagatcagtg ggaaagtcca
    11821 gctcaacctc atttctccat ccctctatga gggcgggggc gtactgttga gcttcttaag
    11881 cgatcgacgc caactcgtcg acaccactac gaaatctcat gtggtgatgg acgcgctccg
    11941 tggagcaatc ctgcatgata tgccggaggc accaggtgat cttcacgaca tgctctattc
    12001 tgccttcgga ggtattccgg gcgagctagc aacggagatg gaacttgccg caattgggat
    12061 gacgggcacc gaaaagggcg atctgcgtta cccggaggaa atgcaggtgc tgctcacgca
    12121 gctccctgat ctcctagaac gttatgagaa cccaggatcg caagattatc tcaatggtct
    12181 cagcggaacc tttactgcaa tgaatcaatt ccgcgatctg ctcaacctcc agagtgtagg
    12241 aaagcaatgg gctgagcgaa caggagagat ccacacgcac ctcgaaaacg ctctctgctc
    12301 catggaaagc atgagagatg aggctttggg actcgcgcat ggccgcagtg gtcaggttct
    12361 cgggattgtc gagctactgg acctactcat gcgggcaggc gtagagatcc ccgaaaactt
    12421 cttgaaccga gcactggcgt tgagcacgag cctcccagat aggctagccg aagataaggc
    12481 catgatagat ctatctgctg cccactcgtg gtgcaaggga cgcgccggca tggtgatggc
    12541 gctcagccga gtgatgagta ttgcgtcgga atgggaaaag aaaaccgcca tcgcaggact
    12601 aaaaatatct ggaggatgga tcgatgactg ggcagagcac aatgctcggt tcctactgcc
    12661 gaccgcacaa caattctgcc gtagcggtga catttctttc tgccatggag ctgcgggggg
    12721 agtgttgaac tggcacatca tcggcgcagc gacgggcagc caagcgtcca cggaactcgc
    12781 agaaacgtac tacacggagt ttcagaaagt ggccgcaact aacggttggc gtacaggact
    12841 gtactcttcg ccccatgccg aaggtttctt tgtcgggaga gcaggatggg acctagccac
    12901 cgcagcattc gaaggccacg ccacctttat tccgcgaatg atcagtctca gcgtaggaag
    12961 gcggtgcgca tgacacacgc accccagagc acttcaacgt tcaagccggc acggcggaag
    13021 cctccagtga tcctacagct cgcgcaaagc gaatgtggac tgtgctctgc cgcgatgatc
    13081 cttgaatatt ggggttatcg tggcgccatc tacgaaatgc gacgcaacac cgatccagga
    13141 agagacgggt tgggtctcaa ggatgttgca tcaatgctaa ctgagcgcgg catcaacgtg
    13201 aacttcgtgc aggctaactt ccagggactg caacgcgtaa atgagccatt catcgctttt
    13261 tggaagggct atcacctagt gctggtggag aagctcaacg aacagcgagc gatcatccta
    13321 gacccagctt ctggcagggc gcggatttcc gccgaagaat tcgaggaaag cttctccggg
    13381 cacgccctgc tctgcacacc gacgaagcac tttgcgcctc agcgggaaag gggctactcc
    13441 attcgcacca tctggcgtga gctaacgact cgctcctata tgggaagtgg tgcgaaaatt
    13501 ctactgctgt ctctattgct gtatgtcttc acattgggaa tccccatcgt gaccaaggaa
    13561 ttggtcgacc ggaagaatga gttgattgac ggttactcaa ccgtagcgat cgcattagta
    13621 ctcatattgc ctttcgttat ctattcgctc ttcgggatcc tccgcacgcg aatcctggcg
    13681 acgatgattg cgcatgtcgg tgaagacctt atgggcggtg tgttcaaaaa gttgttgagc
    13741 ctgccttatc gattttttgc ctcgcggccc aacggtgagc ttatgatgcg cctgagcagt
    13801 gtcaatcagt tgcgcgacct ggtttccaac caaatcaccg cggtgttgct tgacgtcggc
    13861 gtagtgatat tcatcgtggg atacttggtg ttcgccattc cgtgcctctc catcgtcgct
    13921 attggcctca gcgcgatcat ggtgctactc accgtgggga cgtggtcaca ggttcaacgt
    13981 gtaactgatg aggaaatccg tgcattgggc aagtccacgg gtacgcagat ggaggccatt
    14041 acggccatca gctctgtgaa aaccacgggg atggcaccga gtttctacac cagatggcgc
    14101 aaggattatc agggtgcact gcactccggg cggcgccgca tgctggtcca aggcaccgta
    14161 gccacgatca tcggggcaat ccagatgttc ggcccattcc ttgtgctggc tgtaggcatc
    14221 aagctgctct tgaagggcac gggaaccttg ggtgaagtcg ttgccgcaca gtccttggcc
    14281 acgatgctgc tggcttccgt cagctcactc agtttggcca tcagtcagtt tgtaaaggcc
    14341 caggtgcaga tcgcacggct catcgacgtc atgacgcacg agtccgataa cacttgggga
    14401 agcgaagtgt gcgaactgtc cggccagatg acagtggacc agctgtcctt tacttacccc
    14461 ggagcgcagc tgcctgccct cagcaatatt aacttctccg tgagccctgg ggagaaggtg
    14521 gccgtcgtgg gcaggacagg ctctgggaaa tccaccctgg ccaaggtgct cgtggggctg
    14581 tttcccccct cgacgggctc catcacgctg gatggtcgac acagctccga attgtcagaa
    14641 gaatcctttc gcaaggctgt ggcgtacgtg cctcaggaca tccaactgag taatcggcag
    14701 attgcggaaa acattgactt caccgggggt accccggatc tggagttggt gcgtaccgcc
    14761 gctcagatcg ctcagatctc tggaacgatc gagtccatgc ctttggggta tcacacagaa
    14821 attcaggaga tgggcgcgaa tatctctggt ggtcagcggc aacgcatcgc aattgcccgt
    14881 gcgatcgcta ggcaaccaaa aatgattgtc ctcgatgaag caacctctgc tttggacaac
    14941 atgacagaga ggaacgtggc acaatccctc gcagagctta actcggcaca gatagtgatc
    15001 gcacaccgga cgtccacgat ccgatcggcg gacagaatcc tggttctcag ggaaggtcac
    15061 ctggttcagg agggcacatt cagcgaattg atggccgagg acggtgaatt cagagaactg
    15121 atgagcagca cgaaagatct caatgcgact cgtcaagaga tgcaacgatg acagaaaaag
    15181 catggggtag ccgacgtccc cacaagctat taatcacagt caacgacaca aagtatagag
    15241 aaaacgacag aaaatgattg aagtaaaaaa cttagaaaag accctcggta aggagaagat
    15301 tctgcgagga gtgtccttta gcgctcccgc aggtaaaatc accggcttcc tgggccccaa
    15361 cggatcaggc aagaccacca cattcaaggt catgctcaac ctcatgaggc cggacaacgc
    15421 tgacgcaacc gtcacattcg ctggtgaaaa actcagcagc ttccccctgt ccctcactca
    15481 tgtgggaaca tccatggaca tcaacgccat ggacaagcac cgcaagggga tcgatcacct
    15541 ccgttctctc gcaccgcttg cccaatgctc tgaggctcgg gttaatgaac tcatggaaga
    15601 gttcggccta ggacacgcga aaaacaaacg ttccggttca tattccatgg gcatgaagca
    15661 gcgcctttca ctagccactg ccctgctggg tgacccagat ttcctcgttc tcgacgaacc
    15721 caccaatggt ctagatcccg agggcatcgc gtggattcgc aattaccttc gcgcgctcgc
    15781 tggccacggc aagacagtgg tgatctcctc gcacctgctc aacgaggcgc aaaagttcat
    15841 cgactatgta gtaatcatta aacagggaag aatcgcttat gagggagaca tctcgcagtt
    15901 gcatgcactc tgcgaacagc gcaccggcag aaaagtgact gacttggaag aagcttaccg
    15961 ggtcgtcacg gctaaggagg agaactaaac gtgttgggac cacaactgat atccgagtgg
    16021 aagaaggcca caaccagcat cacatggtgg gccgtaggcg ctctcattgt cacggctaac
    16081 gtcctggtca cgagcttctt cacctttgtg gggcttaacg tggagcgctc acccatcgat
    16141 gcgaccgccc cagattccgt gcgtatgttt ctcacggttg gcgtagcatt taccttcatt
    16201 ttgcctctca ttttgggtat gctcattgtc aatctcgagt tttataacaa caccatcatt
    16261 tattccttcc tggggaatca acgccgcggt agtctctatc tagccaagct cgtgacctgc
    16321 gcggtgtcgg ccatgttgtt ctctgtccta tttgccctaa tgtccttggc agttgttgca
    16381 gggctgctgt ccagttcatc gaaacctgca accgtcttca cagggcaaac gtggggtacg
    16441 ctgctgagca tcgtggtgat cagcaccctt ttaggggtca ttggaggtgc cttaggcgcc
    16501 ttggtaacta agccgatgtt ggctattgtt ctcattattt tgtggagcca ggttattgag
    16561 ccaattcttc ggatcgcctc ccctaccaag gcacaggggt atcttccttc ctccttaatc
    16621 gacgctagcc taggcggtgg tttcctagga cagatgttca acagtgagca attatcacag
    16681 ccactagcgt taggtattct tgccgcggtg accgtggttc tcggcattct cggtggtgtg
    16741 aagtatgcgc accaagaggt ataagtccgg tgcagaagca aaaggagccg atcgacaccg
    16801 ccattgccac gtttctgcca gagctgcaga acgaaacgaa gcgacaaact gtgcgggagc
    16861 ttattgagga atttgctgag tgtacgccgt ggtaccgcta ccagtacacg caatcgacta
    16921 acgctacgtc acttgagcag gatcgcagag atcctcaagt acagccgtca ttagcggatt
    16981 tgatgcgcgc catccgcaac atgaacattt ctgagcatcc ctcgcaggac gatcctcgct
    17041 ttatcgagtg gttcttagag ctgacgcggt cgtggacagc gctcctcaat agcccttggc
    17101 aagcggcact gcgatttccc ccttcccagc ggttgacgca cagcattgaa atggacttgc
    17161 tacaggtcat cgagactcag ctctttcgct gcgtggcgga tagtcttgag aagcgccgga
    17221 tggccggaga cctatccggc gtgtccagcg ccgagcgttt tgatgatttc tatcggtggt
    17281 tgagctccgc cgagggatgc gaacactttg aggaaaatta cggtggtcag gttgttcaag
    17341 ctttccatca actgcgattc cgctgtgatg cttggtgtga actgcttgtt cgtctgaata
    17401 tagatctcga ccaaataaat gcgcactttt tcgctggcgt ggaccttcgt tcgttattac
    17461 cacagctaca ggttcagatg ggcgccggag attcacactg tcgtggccga gccgttgcga
    17521 tcgtgaacct cggcgatcat cgttttgtgt ataagccgcg tgatttgagt gttgaccagt
    17581 cactcaagtt cttttttgat gaactgcgcg agtggacagg catccaggta tcggttcctt
    17641 cggttatcgt cgcgcggggt tacggctggg cggaatttgt tactggcgct agtggagatg
    17701 tggattttca gcactatggg cgggctctag gtttcctcgc gagcatagag tttctcgccg
    17761 ggggcattga tttccactac gagaacgttg tgggcaccgc tgactctgga gtatctatta
    17821 ttgacgcaga aacttgcgtc ggtgccagcc cggtgaataa aaaaacctat gcctcaggat
    17881 cgggctccat ggtgggagca cagaaagtct tccattctgt catcagcacc ggattgctgc
    17941 cacttcccca ggttgttccg ggccgtatcg gcatcattga tgttggcgca acaggtatca
    18001 cggaggggga gaccacgtct ccctttaagt ctttgcttgc caagaaccct ggctccgatc
    18061 tgatgcatat cgcttttgag aatctcccgt atcgttcaga gaacagcaat cctcagccac
    18121 ggaccacggt ggcgggtgtc gtggaattcc gtgaccagat cgtcggagga gtgcgggaag
    18181 gactagagtt cgcaaaggct aataaggaag aactctgtgg cttgttcgag cgcgcatttt
    18241 cgggacagag tttccgcttc atcaacaccc ccacgcagac ctacagccaa cttttgcgga
    18301 tggttaccag tcctggggtg gtaaatgatc cagtggcgca tgttgcagtc ctgagccgct
    18361 gcgagatgtt tagtgaccga gaaaaatccg ccgcagcctt cgaggttgaa cagatgctcg
    18421 acggggacgt cccatatttt cagatctcct ttggagataa ttgcctctac gggatggaag
    18481 gagagcccct catcgacggc tttttcgaag gctctcccaa ggaaaccatc tttcgccgta
    18541 ttcacgagct agatgacgaa tcgatcaacg agcaagtgga tctatgcatg gctgctttcg
    18601 ctcgatccct gccagttggg gcagaaggaa ctcccgcgtt gggcgaggct ccagagtgtt
    18661 ccgtggatgt ggacgtcgct ttacaaacag gagccgagct tattctcgcc cgtggctgcc
    18721 gctctgacaa cgaccgccaa cccagcacat tctggggtcc acagatctcc gtggaggatt
    18781 ccactcagtg gacactggga acggcaggat acgacctcta cggaggaagt cccggggttg
    18841 ccctcgcact ttcggcgtct gagcgtcgat tgcgcaccgg aaaatatggt gagtttgcag
    18901 agacagtctt tggccctatc tctcatcaaa tccttgatga ccttatcaac gatggaacct
    18961 atggcatcgg tggttacatg ggagttgccg gaactctgtg ggcagccgtc tgggacaggc
    19021 gcctgcgagg ccttaattac ggcgatattg ccgtagagag cctgaataaa ctcagccaga
    19081 atatagaggg aaagacttct gccgatttcg tggtgggtca atctggtgcc ctcgccgtcg
    19141 cagtaaatct cgcacggatg tgctcagata ttggcattga tgtctccgga atcatggaga
    19201 caatcgtttc ctacagtctg ccggtcttgg aaaaagactt ccgagaaggt tggataggaa
    19261 cgagtgagtc cactccctac tcaggattcg cccacggcct cgcgggcagc atggccagta
    19321 tcgccgccgc cacaacagtt ctttctcctc agtcctcact gaaggcacaa gcagagaaag
    19381 tcgttcagga aatgatcgat gccctggagg gtgtggtaga caacacgggg gcagttacgc
    19441 gttcgaagac cgatcaaaga aaagacgcgg catggtgcca cggttcccct ggagtccttc
    19501 taggcttcac gatcgcttgg gaaaatggat ttcgaacaga cccggaggtt ctccacaatc
    19561 tagcccaata tgtccgtcgg cgtggcgtcg gtaataattc aacggtatgc catggagacc
    19621 tagggtcact gcgtgttctg aagcggtacg cagagttagt ggacgatgag gcactggcgg
    19681 cgtcgataca caaagagatc gtgaaccgct caaaatacat cgcagtaagg aaaaggactg
    19741 attaccagga caaatattcc tccacggact ccctcatgct cggacgagcg ggggccatcc
    19801 tcacgctact ccacgagctc gatccacgag aatacccgga cgtcacaagc ctaggaatat
    19861 aaagacaaac gccttgcatc acattgcgat tcacgcaggc ggcgaagttg cgaagcaatt
    19921 atcgtcagaa ccaacaaggg agccgccgtc atcatcacgg caaacaacaa tgacccactc
    19981 aatacccgca tcttcgaccc agtgactcgt gagcttcgcg agaagaagtt cgtgaagatc
    20041 cgcgtccccg ggggtgcttc tgcaaccata aggagcgaat accaccggtc aacacgcgaa
    20101 agattcacct ctaaaatcat cacacttccc caccgttgac gttatagtcg ccgtatgatg
    20161 atctcctttt ctcttcgacg ccgaggttca cgtatcgcca cctccctcgc cgctgcatca
    20221 gtattgttca cgggagttgc tgtgcctggc gtggtgagcc ctcccagcgc ccaggctcag
    20281 tcttccgagt ttttcggttc cattgccgac atcacgccag gtagtctggt caagtccacg
    20341 cctgcgatgg cggatgtgcg cccttattcc aagcccacgg ccgattccgg tttgcgtatc
    20401 ccgaatgcat ccgaagcgca gggtcgcacg ggtgtgccgt tgggtgaggt ggacttggat
    20461 ccgatggtgg gcctggcgca ggcggctgtt cagaagcgct tcgtgtattc cacaacaaat
    20521 cagcatggtg aggttgcaac cagcacggga acggtgttcc tcccggctgg acctgctcct
    20581 gagggcggct ggcctgtgtt ggcgtgggct cacggcaccg tgggcttggg cgaccagtgt
    20641 gcgccatcga tcaaccagcg aagccctcgg gatgcagagt atctgaatca ctggctgtcc
    20701 cagggttatg ccattgttgc gactgactat gctggccagg gcactcctgg gctgatgagt
    20761 tacttaaacg gacaggccga ggcggacagc gtggtggatt ccgtgatcgc ggcgcgcgcc
    20821 ttgggcagca tggccaagga cggctcctcg ttgctgtcgc atcgctgggc agtcatcgga
    20881 cagtcgcagg gcggcggtgc cgcattgcag gtggcgcgtt tggcaacgca acgcagcacc
    20941 cctgcgggtc ttgatttccg cggaaccgtt gccacgggcg cacccgcata tgtggaggag
    21001 attgtcgctg cgggaggccc tacattcccg ccggtgacgc ttcccactgg gctgaatgtg
    21061 tacgcgctgt acatccttgc tgccctgcgg gaggcgcgtc ccgatattga tgtgaactcc
    21121 gcactgaacg agcagggtcg gcgcatggtg gacgccgccg aaaccgcttg tttgggcgag
    21181 ctatccgagg ctatgaaggg cgtgaatatc gcccatgggt tctccaagcc gttgcgttct
    21241 gtgccaggtc ttgtggacgc ggcacggtcc atgatggcca ccccggcgta tggttatgac
    21301 cgtcccgtgt ttgtgggcca tgggctgaag gacatggatg ttcccacacc catcggactg
    21361 ttgctgaaca ccgatatgtg gttccagcag ttcaacctgg atgcccatgc ccgcaacacg
    21421 cgcgtggagg tgcgctggta tcccacgaat cacggggaca cggtctttgc ctcagttcct
    21481 gattccactc ctttcctccg ctcgattttc aactagcgtg ctggggcatc cggcacgata
    21541 gagcccggtt caccggggcc acccggcgcg ctggggtcac ttggctcgct agggtcactt
    21601 ggctcgctag gtccggcaac agcgctcgct gtacggcccc accgggagac ctccacacgg
    21661 acatcctcac cgatgacctc acatgcttct aaggtcgcat ggttctggtc agcgaaggcg
    21721 gatgccgtgg cgcaggggtc ttcggtgtct ccagtggcca gcgctgttgc ggcagcgatg
    21781 gcggtcatat ctgcggcaag ctgtgtctcc tgggcggcgg acagcagctt cacgccagag
    21841 ataattccta tgctcagtgc gatgagccca aggatgatgc tggctccata tgttgtgctc
    21901 atcgcgctgg cccttctagc tcgcgcggta gatccccgtc gggttctgcc gcgcggggct
    21961 ctgtaatggt cacggcttcg ccatgcacat cgaacagcgc tgcgtgccga gtcacctgga
    22021 cccgcactgc ctcgaggtcc cccactgtgg ttgcggagac tgtgacccgc gcatccggac
    22081 tgcgtgcggc aactactgcc gatccgttgt gacccagcgc ttcggcgcgg gcagcatccc
    22141 gagccaggct ggtcaccgca gcgtgttgtg ccagggtgat gaagcctcct accagcgtgc
    22201 ccgcggtcag ggttagggcg ctcaacacca cagcgccttc gattgtgttc atggtgccgt
    22261 tgtcacttcc tgctacttgc caccctcgtt aagggctcgt tcgaagattc cgcgcagtgc
    22321 atcttccacg gctccagaag tgacgaccgt atagagcagc gctcccagtg cagctgctgc
    22381 cacacagccc agggcgtact caatggtgga catgccgcct tcgtcgtcga tgtgatcccg
    22441 gcaggctttc agagcacgtg cccacatccg aacgatgagg ttgggatgga agagagctgg
    22501 gtccacatag tggttctcgt cgggcgtggg ctctgccgaa atcggctcag ccagtgcggt
    22561 cttgctcaca accggctctg ccagagcagg ctgccccaga gcaggcttag tcatgacgtc
    22621 ttcggtcgtc acggggtcaa tcgtgataga catggtgtcc ttcctttcag tgtgtgtggt
    22681 tgatatgtaa aagaggtcag aggctgcggc catgcacggc atgcgtgcgc catggatgcg
    22741 tcacggatgc accatggata gatccacggc taggtcacag ccctgcgagt ccaagcgcca
    22801 agggaataag tcccgtcacc acaaaggccg gaaggaagca gagagtcagt ggtgctgcaa
    22861 gaaccaccaa catcttttct gccgcctcgg ttgccttatc cagggatagt ttccgcagat
    22921 attccgcatg gtgtgccata gcatccgcca gcatggcccc tgaggtggac tgttgcgcgg
    22981 ccatccgcgc gatcggcccg tagaaggggt cttctgccaa ctgttcccat gcgctcgccc
    23041 ctgcaccgag gtgaagaagc gcgggaattg cccggactgt cgagtgggac ccgtcctcct
    23101 ccggcacgaa agcgctggtg ctgacggcaa gctcccaggc gtggacaagc ggggcgcctg
    23161 cacgcagtgc tgcggcaacg aggtccagca cgcgtgctgc gccagtggga tcatggggcc
    23221 cggcgcgccg ccccactcca ccgagcacgg tggctgtgag cgcctcggcc cacaggaccc
    23281 cggcacaggc caagagtgtt cccactaggc cgaaaaggct tcccaggatg gactgcgtat
    23341 agaagctgac cgtccccaac cctagggact gcccgagaat cacagcaccc ggcggcaggc
    23401 tcagcagcac cacgaccgtc aggcgggcgc cacccatagc gctatgggtt ttcgaatgat
    23461 gcgctagtcg cgcctccaga tcgcgacaga acgtatccag cagatcgccc aggcctattc
    23521 cgtgttcggc ggcaagagcc cacaacacca ggaagcgttg ttcggcctct cccccgccat
    23581 cggcagggtc gatggcacct cccatctcgt ggatacacgc agtcgtgcgc atcctgtggg
    23641 caagttcctg tccgcgttcc tgcgcacgct cgctggactg catcgtgctg caggccgcat
    23701 ggactgcggt ggggatgcgc gcacccgcgt ggcaatccct ggccaccagg cgtgcgaact
    23761 cgaggagcat gtcgatcccc tgccgcacgc cacgatcgtc gactattctg cgacctactt
    23821 tccatcccac gtacccccac aggcttgcgc agaacatcca tatcagcaca gtcatggggc
    23881 actcctctcg ctatcgcact gagctcgctg ccgctggatt cgtcccacaa catcgtcggc
    23941 atccatagat gactgatgga tgctccacac cggttccacc acgagaacag gtgcaccatt
    24001 ccgactgtga gaggcatgca gcgtggagat gtccgtgagc tttcggcctt gcggggtgcg
    24061 ttccacgtgc aacagcacgt cgatgccgtc gaggctttgc cgcaccaggg agcgcggagg
    24121 catgtcagcc atcgccccca aggcttcaag ccttcctggt actgcctggg ggtcattagc
    24181 atgcagcgtc ccagcgcttc ctggatgccc ggtgttcagc gcaaccaata ggtctgctat
    24241 ttccgcgcca cggatttccc ccacgatgat ccggtctggt ctcatgcgca ggcactgtgt
    24301 caccaggcgc cccatgggaa tgtcgccagc tccttcggca ttagcccggc gcgcggtcat
    24361 ggccagacag tgcggatgct cggcaatgat ctctggggtg tcttccacca ggatcatgcg
    24421 ttgattgcca ggaacctccc ccagcagcgc tgtgagtagt gtggttttcc ccgccccggt
    24481 tcctccactg atgaggatgt tcatccgctg ccgaacgatc tgtcgcagca ccatccctag
    24541 tgcaggtgac atcatgccgt cgcggacgag gtcttcaaca tggctatgcc ctcggtgcag
    24601 tgctcgcagg ctgatgcttg ccccaccgtc catgggtggc gcgagggccg cgtggacacg
    24661 caggcgtcga gcagggatcc cctccggcag gcctgtgagc actccgtcgg caaagggcat
    24721 tgcattgtcc agccgagcac cacaccgagc tgccagccgc accgccaatt cccgagcctg
    24781 ccctggcggc acagggggca tctccgctgg ctctaacccc tcaccgcggt caatccagat
    24841 acgcccatcg ggattgacca gcacatcggt gacgtcggga tccatgaaca gctccgtcag
    24901 gatccccagg ccggaaaact cgcgatggag cgtccgcaga aattcgacgc ccccagcgcc
    24961 gccctcacct ccgccgtcct gctgggcgtg cccgccgaac tcaaccaggt cctcggggcc
    25021 tacgtgacta attccgcgct cagctagggc tcggcgtacg gcgtcgatgc tcatggtggt
    25081 catgccgcac caccctcgtc ggtagcgcgg gccacatcat cgtctcggaa cgcatcgtca
    25141 ccgcggagcg cgtcgtcacc gcgcggcacg tctgctccga gcagctcctt cacgagcagc
    25201 gtgtggtcct tcttccattc ctggaccaga ctgtctgccg acctcaccaa ggaatgcccg
    25261 tcatggagga agtgctccgg ctcccccttg ttcagcgctc gggccaccgc ggcatccgag
    25321 cgcactgtgc gcatgcggta gcgctgcaga atcaccggca tgagcgagtg cggaacgtcc
    25381 gatccggcga aatctcgcac cactaccagg ggatccacgc cccagtgatc ggccaggcgg
    25441 tcacacagcc tcttcgcgta catcagacct gggacggtgg ctatggtgac gacgacgtgg
    25501 gcgtcgggca ccatgactga gggattgccc ctggagttgc cgcttgcttc gccaaaaatt
    25561 gtcagaaaat catcgctgcc tggcctcaga gtcccacagt cggcgacaca cgcggcgctg
    25621 cccaacagtg ctggctgctg ccactgtgtc ccggcctggc taataatggg tatcttcccg
    25681 atcctcggag cacgagacag caactgtatg tagttgcact ccagcaacgt acgcaccccc
    25741 aactccgaca cactatgctc cttgcccagg gcgatatcga cgccgaggga atgcgggctg
    25801 gcgtcgagta ctacggaggg ataatcacca ctcagcgcat gggcaaagca cacgctgaac
    25861 accgtggtgc ccgcgccacc cacggcacca taaacagcaa tcaggggcag atcatgcatc
    25921 cccaccaggc gagcaagatc cagcacacca ccctgggaca acgtgcgtga cacctgcgta
    25981 gaatcaggag ctatgtcgat cgcgcggatc cgcggatggt tctgcagcgg attcggacgg
    26041 tcgtggatca gaatggctgc agcacccccg gctctgcggc gagcgccgct gctccgcaca
    26101 tcatccaggc cttcgagggc tgcatggatc cgctccacgg cttgcggcgt tgcggcggag
    26161 agaagcgtcc ggcccgtagc cgccgcgatc atctgcgctt cttccaacca ttgcgcatcc
    26221 tgcacatcca cgatgaccgg acgtgcgtcc gctgcgcgcg tcttcgttgt gcgtatctcc
    26281 gctgcgcgcg ggccacgctc ctgcacctgt ggtgttgcgg catgacgtgc catcacgttc
    26341 ccccaaacgt tggtcgatcg ttactgtccc gctgccatcc ccttatgcgg cagcgagcct
    26401 tatgaacttg agtgacaggt tccagtcttg cccatcgtca agtaactacg gaaggggtac
    26461 gtggaaatct gtggataact cgtcatagcg cccctttttg agccagttga ctgtggataa
    26521 cacatgtgca gcaccaccag tccatcacgc acgcatcacc cgcgcgttac gcaagtggca
    26581 gcaatggcgc atgtgactga tgtgacatag aatacgaatc gtgcacccaa aaaatgtcac
    26641 caccacacac cccacgaagg tgctggcgat tttcgacctc gacaagacga tcatcaacac
    26701 cagcgcctcc ctggcctacg gacgtcccct ggccgaacgc gggctcatca ccaccaccga
    26761 agtcatccgc atgatcgcca tccgcagcag cttcatgctc accacccacg accaggaaga
    26821 cctcaacgcc accaaagaag cgctagcctc catgatcaag ggccgcgaag ccgaacccct
    26881 caagaccgtg gcgcgcgaag ctcttcacga cgtcatcatt ccttatatct acgccgaagc
    26941 ccacgagctg ctggaatggc accgagagca gggccacacc atcgccatcg tcacggcttc
    27001 accatccgtg gtggtggaac ccatcgccga agaattaggc gcagacatcc tcatcgcctc
    27061 cgagctggag gtggaagacg gcctcttcac cggcaacgtc accctgttca acaagggcgt
    27121 gacgaaggtg catcacatcc aggacatcgc cggggaacac ggctttgacc tctcgcagtc
    27181 ctatgcttat tcggactccg gcaccgacgt acccatgctg gagctcgtcg gccaccccac
    27241 cgccgtgaac cccgaccgcg ccctgaagaa agtcgccgcc gaacgcgagt ggcccatcgt
    27301 gaacttccga cgccctgagc cgatcaccca gagcaacgtg gccgtcctcg ccggcgccgg
    27361 tgccaccctc gccatcctgg gcgcggtggc cacaagcgtg accctctggc tgttcaatcg
    27421 ggattcctcg tccagcgatg gctcaggcca ggcggacgtg accccggacg cagcctagcg
    27481 ctacacacac gcgctaggcc ttcgcacaat cgctaggcct tcgcatccgc gatggactta
    27541 gcctccagcg ttccctcggc aagtccctcg gcgtggaaca cgatccactc ggccacgccc
    27601 tcagccgtgc cagacgcaaa tcccttcgct ttggcctcat actcatcccg atggcggttc
    27661 caccacacct ccggcacgcc caaaccgcgc ggatccagcc cggtggaaat cgtcgccaaa
    27721 cgcgaacacg cgcgcgccgt cacgccgttg gcatccgcaa aaggctgcag tgccagcaac
    27781 tccccgtgaa tcaccgccgt cagcaccacg gcattcacct tcgtgccgcc agtgatgaag
    27841 gaccccagca actgcaggcg cccgtccgcg tccctccgcg ggcgccccgg caccaaaaac
    27901 tcggcggatt gcgctgcctt tttgcggaaa tcctcgtcgc tcatctgcgg gctcgccacg
    27961 gaattgattt tcgcaatgac ctgcagcggt gcgcgtcgaa atgttgtctg cgtctccgtg
    28021 atcccatccg gcgccagcag ctccgccgcg cgcaacgcac ccgccaggat ggggtcgttg
    28081 acctgcccat cctctggcaa ccagggggtt ccgccgtcaa tttgagccga cgccctagct
    28141 cccctcaaga cagcctccga ccccgtcaca tcccagccac gcaggttcgc cttgtggcga
    28201 tggacgcggg aaatatagtc cacggctttg tccacggcct cgggcacgcc cggtagctct
    28261 gccagaggtg ccagtgggtc gggagcggac gctgtaggtg agtttttttg gctcatgcac
    28321 cgcaagttta gtcaaccaat aaggcaaaac ctccgcaggt ctggcaaaat gggtgaggtt
    28381 agctgaaatt acaggagaga ctaagtgagc aacaacgacc agaacggcat gttcaccgac
    28441 cgcgatagct tcaacccaac cgtgaatagc attccgctgt ccgacgttga tacccgcgca
    28501 aagggccagg gcagcatcgg tgatctggtg aaggacgctt cctcccagat ctcctccttg
    28561 gtgcgctctg agattgagct tgccaagact gaggttgcta cctccgccaa gaaggctggc
    28621 attggcgtag gcctcttcgc cgcagccggc atcatcttgg cctacagctc cttcttcttg
    28681 ttcttcacca tcgccgaggg cctggataac ttcatgccac gctggctggc attcctgatc
    28741 gtgttcctct tcatgatcgt tctcgtggcg atcctggctc tggtgggact caagcaggtg
    28801 aagcaggtga aggcgccgga gaagaccatt gattccgtcg gcgaattgaa gactgtggtt
    28861 cctagccgtg gtggtaactc cgcagccgct cgcgcggccg accaccgcga tcctggcatg
    28921 tacagctagg tcaaccagga actctcacta tcacagtgcc taccagcacc tttattcact
    28981 ctcggggcgt gcggcttcgg gtccaggttc agggcccgcg caacgcccct ttagtgttgc
    29041 tgattcacgg cttcggaggg ggatgcttcg actgggagct ggtcatggac gaactcgccc
    29101 atgcggagac cagcggtgtg agcaacgcca gtggcgccag cagcaccagc gtagtggaac
    29161 ctcgcgtggc ggcagtggac ttacgtggat atggggaatc ggataaaacc cctcgcggct
    29221 acgacctcac cactgcagcc agcgacatgg ccggcgtgat ccgcggcctg ggctactcca
    29281 aggccattgt tgtgggccac ggcttcggtg gcatggtcgc ctggacgttg gccgcgcatg
    29341 agccagagcg tgtcgccgcg gtggtgacgg tggcgtcggc gcacccgctg gtgcaattcc
    29401 gctccttact tgtgcagccg cacaagcaat ggcggcgcat gaggcgcact cttgcggctc
    29461 aggtgccgcg ctacccggag acccagattg tgaaggacaa cgccgccaag gcggagcgca
    29521 tcttccgcag cggcgtagcc ccgggtttcc gcgatacaga aatctacaac aggttcgcag
    29581 gccaacgccg cgaggcgatg cttgtggaca aggtggctca tctgtctgcc gagtatcagc
    29641 gctggccttt ccgctcgcgt ttgcggcccg aaggtggcgt gttcgaacgc tccttccctg
    29701 cgcgcaccgc cgcccccgtg ctcgctatcg aaggcagcat ggatccggac tattcacctc
    29761 aggtggccga acgctccgtg gctcgcagta gtaacgggcg cgtagaactg atctacgggg
    29821 tgggccacta tccgcacatc gaggatgcac ccacggtcag cg
//
