LOCUS       NZ_CP060417            21612 bp    DNA     circular CON 22-JUN-2024
DEFINITION  Bacillus subtilis subsp. subtilis strain ONU 559 chromosome,
            complete genome.
ACCESSION   NZ_CP060417
VERSION     NZ_CP060417.1
KEYWORDS    RefSeq.
SOURCE      Bacillus subtilis subsp. subtilis
  ORGANISM  Bacillus subtilis subsp. subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4004302)
  AUTHORS   Ivanytsia,V., Vasylieva,N., Ostapchuk,A., Kalinowski,J.,
            Rueckert,C., Luzhetskyy,A., Rebets,Y. and Shtenikov,M.
  TITLE     Comparative genomic characteristics of Bacillus from anaerobic sea
            sediments
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4004302)
  AUTHORS   Ostapchuk,A., Kalinowski,J., Rueckert,C., Luzhetskyy,A. and
            Rebets,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2020) Microbiology, virology and biotechnology,
            Odessa National after I.I. Mechnikov, Dvoryanska, 2, Odessa 65082,
            Ukraine
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 12.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014298115.1-RS_2024_06_22
            Annotation Date                   :: 06/22/2024 02:49:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,114
            CDSs (total)                      :: 3,992
            Genes (coding)                    :: 3,914
            CDSs (with protein)               :: 3,914
            Genes (RNA)                       :: 122
            rRNAs                             :: 10, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 53 of 78
            Pseudo Genes (incomplete)         :: 35 of 78
            Pseudo Genes (internal stop)      :: 13 of 78
            Pseudo Genes (multiple problems)  :: 19 of 78
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:10:09
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3611367
            Orig. end                         :: 3632979
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP060417.1.
            Bacteria and source DNA available from Collection of the sea and
            useful microorganisms of Odessa I.I. Mechnikov National University.
            Address:  Ukraine, Odesa, Shampanskii lane 2/2.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21612
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="9"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     cand_cluster    1..21612
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21612
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11612](+)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11612
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     misc_feature    complement(111..125)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.21"
                     /tool="antismash"
     gene            complement(203..3889)
                     /gene="narG"
                     /locus_tag="H8S71_RS18460"
                     /old_locus_tag="H8S71_18455"
     CDS             complement(203..3889)
                     /GO_component="GO:0009325 - nitrate reductase complex
                     [Evidence IEA]"
                     /GO_function="GO:0008940 - nitrate reductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009061 - anaerobic respiration [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="narG"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391609.2"
                     /locus_tag="H8S71_RS18460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H8S71_18455"
                     /product="nitrate reductase subunit alpha"
                     /protein_id="WP_169037630.1"
                     /transl_table=11
                     /translation="MKKKKRSPLFRRLNYFSPIEHHSNKHSQTTREDRDWENVYRNRWQ
                     YDKVVRSTHGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGPDMPDFEPRGCPRGASFS
                     WYIYSPLRVKYPYVRGVLNNLWREALQEHQNPLDAWKSIVENPEKAKSYKQARGKGGFV
                     RAEWPEVLKLISASLLYTVMKYGPDRNVGFSPIPAMSMISHASGSRFMSLIGGPMLSFY
                     DWYADLPPASPQIWGDQTDVPESSDWYNSGYIITWGSNVPLTRTPDAHFLAEARYKGAK
                     VISISPDFAESSKFADDWLSIRQGTDGALAMAMGHVILQEFYVNQETERFIEYAKQYTD
                     FPFLVTLSKENGVYTAGRFLHAKDIGRKTKHDQWKPAVWDEQTSSFAIPQGTMGSRWDG
                     QQKWNLHMIDEETGEPIQPRLSVLGIEDEIGTVRIPYFSNDGNKVLERDLPIKKMNLNG
                     EETYITTVFDLILANYGVNRGIGERSAVSYDDPEPFTPAWQEQMTGIKKEAVVKIAREF
                     AQNAIDTDGRSMIIVGAGINHWFNSDTIYRAVLNLVLLVGAQGVNGGGWAHYVGQEKLR
                     PAEGWQTIATAKDWEGVPKLQNGTSFFYFATDQWRYEDQPISDLASPIAASSRYKHHAD
                     YNVLAARLGWLPSYPTFNQNGIDLYKEAEKAGAETPEDVGAYVASQLQEKKLKFAIEDP
                     DNEVNFPRNLFVWRANLISSSGKGHEYFLKHLLGTTNGLMNDDSDSIRPEEIKWREQAP
                     EGKLDLLINLDFRMAGTALYSDIVLPAATWYEKHDLSSTDMHPFIHPFAPAISAPWESK
                     SDWDIFKALSKAVSDLAEEVDMEPVKEVVATPLLHDTMQELAQPFGKINDWSKGECEAI
                     PGKTMPNIQVVERDYKHIFHKMTALGPNVALKPSGTKGMSWSIADEYESLKQRLGEITS
                     DSVAKGCPNISEAKQAAEAILTLSSTSNGKVAVKAWESLENITNLKLKDLAEEREEECF
                     TFEQITAQPKTVITSPAFSGSEKGGRRYSPFTTNVEKLIPWRTLTGRQSYYVDHELMME
                     FGETMATFKPILQHRPFLSKRPDQEGKEIVLNYLTPHNKWSVHSMYFDSLPMLTLFRGG
                     PTVWMNKDDAEDTDIKDNDWIECFNRNGVVVARAVLSHRIPKGMAFMHHAQDRHINVPG
                     TKLTNNRGGTHNSPTRIHVKPTQMIGGYAQLSYGFNYYGPTGNQRDLNVVIRKLKEVDW
                     LED"
     misc_feature    complement(3955..3970)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     misc_feature    complement(3979..3992)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.07"
                     /tool="antismash"
     misc_feature    3979..3993
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.64"
                     /tool="antismash"
     gene            complement(4084..4560)
                     /gene="arfM"
                     /locus_tag="H8S71_RS18465"
                     /old_locus_tag="H8S71_18460"
     CDS             complement(4084..4560)
                     /codon_start=1
                     /gene="arfM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391610.1"
                     /locus_tag="H8S71_RS18465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H8S71_18460"
                     /product="Crp/Fnr family transcriptional regulator ArfM"
                     /protein_id="WP_064671464.1"
                     /transl_table=11
                     /translation="MNQCDYLLFLKQLPMFNEVPLSIVETLLKNGTFIRGSCDQSPSFL
                     HSQSVYIVLKGSVRFVDSRLPEGSKTVALWEKGDVFPIDEKGGLYLSPFISVNATSDIL
                     ILNIPYYIFKKMMSYHPQLQMNFLAMLQQNVFCSYQLFLRYLHTSQDENAEPGS"
     misc_feature    complement(4618..4633)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            4704..5423
                     /gene="ywiC"
                     /locus_tag="H8S71_RS18470"
                     /old_locus_tag="H8S71_18465"
     CDS             4704..5423
                     /codon_start=1
                     /gene="ywiC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391611.1"
                     /locus_tag="H8S71_RS18470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H8S71_18465"
                     /product="YwiC-like family protein"
                     /protein_id="WP_169037629.1"
                     /transl_table=11
                     /translation="MKALIPKQHGAWAMLLIPFLLGMVKGGPVIWHIPLFLGWLFLYLA
                     VYPVTLALKKKQSKQYQKWMCYYGFPACCFLMISVFHKPPLIWVGVSLLPLFLIHMYFA
                     RRKNERALLNDVAGVLFFCSGGFASCWLGMGTLDGWAWFIFLQSALFFIGSSFYVKSVI
                     RERKNRTFAYWSWGYHLLLPFLSALFGAGWAFLAFIPSSLRAWFFHGRDWPVKTIGILE
                     IVNACFFFAVMCLFMTR"
     gene            complement(5455..6171)
                     /gene="fnr"
                     /locus_tag="H8S71_RS18475"
                     /old_locus_tag="H8S71_18470"
     CDS             complement(5455..6171)
                     /codon_start=1
                     /gene="fnr"
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391612.1"
                     /locus_tag="H8S71_RS18475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H8S71_18470"
                     /product="fumarate/nitrate reduction transcriptional
                     regulator Fnr"
                     /protein_id="WP_021480833.1"
                     /transl_table=11
                     /translation="MNFLSVRPSDSDLISSDLHELLESISTKRKMEKHTYLFREGMDAE
                     ELYLIQSGLIEIGKLTSDGKDLTLRICQKHDIVGELTLFTEEPRYMLSAKVLEDGEVLV
                     INKNKLEKELIQNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYG
                     VKRSDGILINIVLTNQDLAKFCAAARESINRMLGDLRKKGVISIDESGKIILHKRDYLR
                     CEIECENCPLEICNID"
     gene            complement(6270..7457)
                     /gene="narK"
                     /locus_tag="H8S71_RS18480"
                     /old_locus_tag="H8S71_18475"
     CDS             complement(6270..7457)
                     /codon_start=1
                     /gene="narK"
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391613.2"
                     /locus_tag="H8S71_RS18480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H8S71_18475"
                     /product="nitrate transporter NarK"
                     /protein_id="WP_124072638.1"
                     /transl_table=11
                     /translation="MINRQHIQLSLQSISLVAGFMVWVLISSLISQITLDIHLSKGEIS
                     LVTAIPVILGSLLRIPLGYLTNRFGARLMFMVSFILLLFPVFWISIADSLFDLIAGGFF
                     LGIGGAVFSIGVTSLPKYYPKEKHGVVNGIYGAGNIGTAVTTFAAPVIAQAVGWKSTVQ
                     MYLVLLAVFALLHVLFGDRHEKKVKVSVKTQIKAVYRNHVLWFLSLFYFITFGAFVAFT
                     IYLPNFLVEHFGLNPADAGLRTAGFIAVSTLLRPAGGFLADKMSPLRILMFVFAGLTLS
                     GIILSFSPTIGLYTFGSLTVAVCSGIGNGTVFKLVPFYFSKQAGIANGIVSAMGGLGGF
                     FPPLILASVFQATGQYAIGFMALSEVALASFVLVIWMYWQERMKTHTERNSQSIN"
     misc_feature    complement(7522..7537)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     gene            complement(7593..9263)
                     /gene="argS"
                     /locus_tag="H8S71_RS18485"
                     /old_locus_tag="H8S71_18480"
     CDS             complement(7593..9263)
                     /EC_number="6.1.1.19"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391614.1"
                     /locus_tag="H8S71_RS18485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H8S71_18480"
                     /product="arginine--tRNA ligase"
                     /protein_id="WP_187001946.1"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELDKLRKDLENFRVPFDVWYSETSLYQNGKIDTALEALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQELKP
                     AADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     gene            complement(9260..9688)
                     /gene="ywiB"
                     /locus_tag="H8S71_RS18490"
                     /old_locus_tag="H8S71_18485"
     CDS             complement(9260..9688)
                     /codon_start=1
                     /gene="ywiB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391615.1"
                     /locus_tag="H8S71_RS18490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H8S71_18485"
                     /product="DUF1934 domain-containing protein"
                     /protein_id="WP_003243604.1"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVTGASTIAKYKMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     misc_feature    9895..9910
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 25.99"
                     /tool="antismash"
     gene            10001..10132
                     /gene="sboA"
                     /locus_tag="H8S71_RS18495"
                     /old_locus_tag="H8S71_18490"
     CDS             10001..10132
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="sboA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391616.1"
                     /locus_tag="H8S71_RS18495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H8S71_18490"
                     /product="subtilosin A"
                     /protein_id="WP_003222002.1"
                     /sec_met_domain="Subtilosin_A (E-value: 8.7e-29, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       10001..10030
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="H8S71_RS18495_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       10031..10132
                     /prepeptide="core"
                     /locus_tag="H8S71_RS18495_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[10000:10030](+)"
     gene            10089..10241
                     /gene="sboX"
                     /locus_tag="H8S71_RS18500"
                     /old_locus_tag="H8S71_18495"
     CDS             10089..10241
                     /codon_start=1
                     /gene="sboX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_054594.1"
                     /locus_tag="H8S71_RS18500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H8S71_18495"
                     /product="bacteriocin-like protein SboX"
                     /protein_id="WP_010886632.1"
                     /transl_table=11
                     /translation="MKLPVQQVYSVYGGKDLPKGHSHSTMPFLSKLQFLTKIYLLDIHT
                     QPFFI"
     gene            10266..11612
                     /gene="albA"
                     /locus_tag="H8S71_RS18505"
                     /old_locus_tag="H8S71_18500"
     CDS             10266..11612
                     /codon_start=1
                     /gene="albA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391617.1"
                     /locus_tag="H8S71_RS18505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H8S71_18500"
                     /product="subtilosin maturase AlbA"
                     /protein_id="WP_015714887.1"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1083.7, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 4.9e-29,
                     bitscore: 98.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.2e-07, bitscore: 28.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 1.1e-44, bitscore:
                     150.8, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 3.4e-06, bitscore: 24.6,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 5.1e-22, bitscore: 76.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 5e-10, bitscore: 37.5,
                     seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.6e-09, bitscore: 36.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIEQMFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRASR
                     HTITTSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDN
                     GVLTCEITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKAYKQKIIVG
                     ISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIVHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSPLVHKLWQAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     aSDomain        10281..10556
                     /aSDomain="Subtilosin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a subtilosin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_H8S71_RS18505_Subtilosin_rSAM_RRE.1"
                     /evalue="3.40E-31"
                     /identifier="RREFam018.1"
                     /label="H8S71_RS18505"
                     /locus_tag="H8S71_RS18505"
                     /protein_end="97"
                     /protein_start="5"
                     /score="98.4"
                     /tool="antismash"
                     /translation="MFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLNKTAYE
                     LCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQ"
     gene            11625..11786
                     /gene="albB"
                     /locus_tag="H8S71_RS18510"
                     /old_locus_tag="H8S71_18505"
     CDS             11625..11786
                     /codon_start=1
                     /gene="albB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391618.1"
                     /locus_tag="H8S71_RS18510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H8S71_18505"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbB"
                     /protein_id="WP_003222006.1"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     gene            11783..12502
                     /gene="albC"
                     /locus_tag="H8S71_RS18515"
                     /old_locus_tag="H8S71_18510"
     CDS             11783..12502
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="albC"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391619.1"
                     /locus_tag="H8S71_RS18515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H8S71_18510"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_003227564.1"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQLKTHRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKMREYCEAGGTILFSSHLLDVVQRFCDYAAILHNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     gene            12495..13805
                     /gene="albD"
                     /locus_tag="H8S71_RS18520"
                     /old_locus_tag="H8S71_18515"
     CDS             12495..13805
                     /codon_start=1
                     /gene="albD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391620.1"
                     /locus_tag="H8S71_RS18520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H8S71_18515"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbD"
                     /protein_id="WP_128740807.1"
                     /transl_table=11
                     /translation="MNNIIPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GIDESVLRKTYIILALLLMNAYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLFWLGRFSFFTVYSIIFGVVLSNHFVKKKN
                     LMFLLHAAIFACVCLSAALMPAATLPLCAVHMLWAVIIDFPVFLQAPPQQGKMHSFMRR
                     SEFSFYKREWNRFISSKAMLLNYAVMAVFSGFFSFQMMNTGIFNQQVIYIVISALLLIC
                     SPIALLYSIEKNDRMLLITLPIKRKMMFWAKYRFYSGLLAGGFLLVVMIVGFISGRPIS
                     VLTFLQCIELLLAGAFIRLTADEKRPSFSWQTEQQLWSGFSKYRSYLFCLPLFLATLAG
                     TAVSLAVIPIAGLVIVYYLQKQDGGFFDTSKRERLGS"
     gene            13795..14955
                     /gene="albE"
                     /locus_tag="H8S71_RS18525"
                     /old_locus_tag="H8S71_18520"
     CDS             13795..14955
                     /codon_start=1
                     /gene="albE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391621.1"
                     /locus_tag="H8S71_RS18525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H8S71_18520"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbE"
                     /protein_id="WP_077671151.1"
                     /sec_met_domain="Peptidase_M16_C (E-value: 4.2e-05,
                     bitscore: 21.5, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYFYGAAAYLK
                     EQIIDAFGCAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVDALLKTFADLSFPS
                     SLSFEAVEKARNELLLRIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRRDRIKAIHP
                     KRFLDATDFIVDLVSQQKQLNILGQVQACDVRGHAPQTSAVTSGRIPVNRHVFETETRS
                     AAGPSVLTLGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAVYHVITRYD
                     VMNNLLLVSICTDQLHEKDIPPRVLEAVSAFHTDERELEQAKQFLRNELLLQFDSPEGL
                     LAYMGILRRFSCTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG"
     gene            14960..16240
                     /gene="albF"
                     /locus_tag="H8S71_RS18530"
                     /old_locus_tag="H8S71_18525"
     CDS             14960..16240
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="albF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391622.1"
                     /locus_tag="H8S71_RS18530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H8S71_18525"
                     /product="pitrilysin family protein"
                     /protein_id="WP_041850411.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 2.4e-13, bitscore:
                     48.2, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKAFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDFG
                     SRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNHQLSYHYQLISMLS
                     PSSPAAVFPAGRIEDIEALDINDLQKAYKAAYQAHRMTLFLIGGSENTETLLPPHLQLE
                     KRPDYHAERKIIPACPPALSQKMVLGDEERMEDTWTGLQIGALPGQNDLLSIKLYWDIA
                     ARILFQLDSPFFQEIQQTYRLEIDRLSAETYIYEDGGFLILHSQGTHSSAYIDVASYYV
                     TQKKEQVAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHIIQDMDAQ
                     VFLSLIDAMASSNKAIIHVSQKEAIRQ"
     gene            16237..16938
                     /gene="albG"
                     /locus_tag="H8S71_RS18535"
                     /old_locus_tag="H8S71_18530"
     CDS             16237..16938
                     /codon_start=1
                     /gene="albG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391623.1"
                     /locus_tag="H8S71_RS18535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H8S71_18530"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbG"
                     /protein_id="WP_187001947.1"
                     /transl_table=11
                     /translation="MKKSTVFTLLLLLIGMAAYSFGWVQAVAEAAAQYVQMINNDAERL
                     GLLACTAALLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHNLCSRYAEDVK
                     SLRDSYKNVRQTYVMAAVLCQVFIFGCMFEIVKAVPFRLHTPPAFSMGLAMLLILYLLF
                     CMRTYLRQLFRHGSLFRKVFAGVLAAAGIWWMLSFSISELLFLIILAAIQQIGSFIYKR
                     FSYRSTASLDL"
     gene            complement(16944..18320)
                     /gene="ywhL"
                     /locus_tag="H8S71_RS18540"
                     /old_locus_tag="H8S71_18535"
     CDS             complement(16944..18320)
                     /codon_start=1
                     /gene="ywhL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391624.1"
                     /locus_tag="H8S71_RS18540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H8S71_18535"
                     /product="YncE family protein"
                     /protein_id="WP_125121079.1"
                     /transl_table=11
                     /translation="MKKNDLSALQENCFCFCDEEISREAPFQVPIDIPEGFKVDSAEAS
                     AAVTWSTDNLSCISEPCLIQTGPEPEDIGVRYAVRVQGTITLLVSVSPVRNQYGQGDGA
                     VSVIHTEEIDQVVYYAAQSDRCPDFSQMKVEDLLIVPPFYGSPLTVAGTLVLPPSPDPQ
                     SYVFTANTGDSTVSVIDADLNTVVKTIPFSAVPTNLGVTFDKAFTYILHGNTNLVSVID
                     NKTLTIINTITVGGGPRKIEFDPTDEFAYVMAAGSIYVINTASQSVIDVIPIPGALDFA
                     LDPNGQYVYTANGSSWSVDKYDVNTGQLVESIIDSFEFPSLIATPYAGNFAYVLNGELW
                     PKGVTEISLSPLSRGGDFSRLFETLMTIVFSLDSTRAYFLEPYSEPFLINNLYVVNTAR
                     QRIIANVSLPGAFDLAVTPDKQYIYAAQPNDNAVTVYRTSDYTAVTVIPVGAGPSAIAM
                     "
     misc_feature    18287..18304
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 21.71"
                     /tool="antismash"
     gene            complement(18359..19714)
                     /gene="ywhK"
                     /locus_tag="H8S71_RS18545"
                     /old_locus_tag="H8S71_18540"
     CDS             complement(18359..19714)
                     /codon_start=1
                     /gene="ywhK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391625.1"
                     /locus_tag="H8S71_RS18545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H8S71_18540"
                     /product="YncE family protein"
                     /protein_id="WP_038829813.1"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAGAEQEECLCFCEGEASREAMFQAPIELPEGFVV
                     DPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEVGVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGDGAVSVIHNAEIDQVVYYSDEPDDCPDISDITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPEPVYAFTANPNDQSVSVIDTNTHTVVTTIALPYNPAGIEITPDKSAVFVLHPNNNV
                     ISVIDYDTLTVTATILLDQPPRLIRFIPNHEFAYVFAGTAIYVIGIDTLTVERSIPVEG
                     FDIAIDPNGLFAYVLNFGLVQKVDLSTGEVLGTIERELIVSSIETDSTERYAYVLEQEF
                     LFNYLTVIDLNTFTIRDTQELEPDGLYVMFTSGSEVYLHDSFTGNLYSVSPNGAGVIGN
                     LPQSATDYAFTPNGDFLYATRFIEQSIIVYNTDDYSEETVISLGVSPGAITI"
     gene            complement(19711..19941)
                     /locus_tag="H8S71_RS20660"
     CDS             complement(19711..19941)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009968328.1"
                     /locus_tag="H8S71_RS20660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_125121078.1"
                     /transl_table=11
                     /translation="MQIPPFIILYMSYFIINILVRSAKKPQFFLSLHRMFGDIFSKRSV
                     YPQQFVQANTLIFHILLYLREQCMSEKEVKE"
     misc_feature    19895..19911
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.81"
                     /tool="antismash"
     gene            19944..21089
                     /gene="rapF"
                     /locus_tag="H8S71_RS18550"
                     /old_locus_tag="H8S71_18545"
     CDS             19944..21089
                     /codon_start=1
                     /gene="rapF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391626.1"
                     /locus_tag="H8S71_RS18550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H8S71_18545"
                     /product="response regulator aspartate phosphatase RapF"
                     /protein_id="WP_125121077.1"
                     /transl_table=11
                     /translation="MTGVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDQREYLSAIKFFKKAESKLIFVKDRIEKAEFFFKMSESYYYMKQTYFSMDY
                     ARQAYEIYKENEAYNIRLLQCHSLFATNFLDLKQYEDAISHFQKAYSMAEAEKQPQLMG
                     RTLYNIGLCKNSQSQYEDAIPYFKRAIAVFEESNILPSLPQAYFLITQIHYKLGKMDKA
                     HEYHSKGMAYSQKAEDVIYLSEFEFLKSLYLSGPDEEAIQGFFDFLESKMLYADLEDFA
                     IDVAKYYHERKNFQKASAYFLKVEQVRQLIQGGVSLYEIEV"
     gene            21073..21192
                     /gene="phrF"
                     /locus_tag="H8S71_RS18555"
                     /old_locus_tag="H8S71_18550"
     CDS             21073..21192
                     /codon_start=1
                     /gene="phrF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391627.1"
                     /locus_tag="H8S71_RS18555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H8S71_18550"
                     /product="phosphatase RapF inhibitor PhrF"
                     /protein_id="WP_009968329.1"
                     /transl_table=11
                     /translation="MKLKSKLLLSCLALSTVFVATTIANAPTHQIEVAQRGMI"
     misc_feature    complement(21219..21232)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.88"
                     /tool="antismash"
     misc_feature    21254..21263
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     misc_feature    21327..21340
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 21.3"
                     /tool="antismash"
ORIGIN
        1 tccttttttc aatgtccagc cgcctttata tttgtcctgg tcctcccatt gcttcgggta
       61 gccgatgccc ggctttgttt ctacattatt gaagtacata tattccgcac cggaacggtt
      121 tgtccacgtg tttttgcaag tgacgctgca cgtgtggcag ccgatgcatt tatccaagtt
      181 catgaccata ccgatttgcg ctttaatctt caagccaatc gacctccttc agcttgcgga
      241 tgacgacgtt caggtcgcgc tgattccccg ttggaccgta ataattaaag ccgtagctga
      301 gctgggcgta gccaccgatc atctgtgtcg gcttgacgtg aatccttgtc gggctgttat
      361 gggtgcctcc gcggttattc gtcagctttg ttcctggcac gttgatgtgg cggtcctggg
      421 catggtgcat aaacgccatt cctttaggaa tccgatgaga caaaacggct ctcgcgacga
      481 caacaccatt tcggttaaag cattcaatcc aatcgttgtc tttgatatcc gtgtcctctg
      541 catcatcttt attcatccac acggttggcc cgccgcggaa cagcgtcagc attggcagag
      601 aatcaaaata catgctgtgg acagaccatt tattatgcgg cgtcaaataa ttgaggacga
      661 tttcttttcc ctcttgatca ggccgcttgc tcagaaacgg gcgatgctgg aggatcggtt
      721 tgaatgtcgc catcgtttca ccgaattcca tcatcagttc atgatcgaca taataggatt
      781 gtctgcctgt cagcgtccgc cacggaatta atttttcaac attcgtcgta aacggcgaat
      841 acctgcgccc tcctttttca gagccggaaa acgctggaga cgtgatcacc gttttcggct
      901 gggctgtaat ttgttcgaac gtaaagcatt cttcctcgcg ttcttccgcc aggtctttca
      961 gcttcaggtt cgtgatgttt tcaagtgatt cccatgcttt tactgcgacc tttccattcg
     1021 aagtggatga tagggttaaa atcgcttctg cagcctgctt tgcttcactt atattcggac
     1081 atccctttgc gacactgtcc gaggtgattt ctcccaatct ctgtttgagt gattcatatt
     1141 catcggctat tgaccagctc atcccttttg ttccgctcgg ctttaaagca acgttcggac
     1201 caagtgcagt cattttatga aaaatgtgtt tgtaatcccg ttcaacgact tggatgttcg
     1261 gcatcgtttt tcccggaatg gcttcacatt cgcctttgct ccagtcattg attttgccga
     1321 atggctgggc caattcctgc atggtgtcat ggaggagcgg cgtcgcaacc acttctttca
     1381 ccggctccat atcgacttct tctgccagat cggaaacggc ttttgacagc gccttgaaaa
     1441 tatcccagtc tgacttcgat tcccacggag ccgagatcgc aggagcaaat ggatgaatga
     1501 acggatgcat atctgtgctg ctgagatcgt gtttttcata ccatgtcgcc gccggcagca
     1561 cgatatcgga atacagcgcc gtaccggcca ttcggaagtc aagattgatt aacaagtcga
     1621 gctttccttc cggcgcctgc tcccgccatt tgatttcttc agggcggatg ctgtcgctat
     1681 cgtcattcat caagccgttt gtcgtcccca acaaatgctt gagaaaatat tcatgccctt
     1741 ttcctgagct tgagatcaga tttgcccgcc atacgaagag atttcttgga aaattcactt
     1801 cattgtcagg atcttcaatc gcgaatttca gttttttctc ttggagctgt gaggccacgt
     1861 acgcaccaac gtcttcaggt gtttctgccc ctgctttttc agcttcttta tacagatcga
     1921 tgccattttg attgaaagtc gggtaagacg gaagccaccc cagccgcgcg gccagcacat
     1981 tgtaatcagc gtggtgcttg tagcgggatg acgcagcaat cggcgatgcc aaatcactga
     2041 tcggctggtc ctcataacgc cactgatctg tcgcaaagta gaaaaatgag gtgccgtttt
     2101 gcagcttggg cacgccttcc cagtcctttg cagttgcaat cgtctgccac ccttcagcag
     2161 gtcggagctt ttcctgcccc acgtaatggg cccagcctcc gccgtttacg ccttgggcgc
     2221 ctacaagtaa aacaagattt aacaccgctc ggtagatcgt gtcggagttg aaccagtggt
     2281 taatgccggc ccctacgata atcatggacc ggccgtctgt atcgatcgca ttttgggcaa
     2341 actctctggc aatcttaacg acagcttctt ttttgattcc cgtcatttgt tcctgccagg
     2401 caggcgtaaa cggctcagga tcatcatagg agacagccga tcgttcgccg ataccccggt
     2461 tcacgccgta gttagccagt atcaagtcaa acacggtcgt gatgtacgtt tcttcaccgt
     2521 tcaggttcat ttttttaata ggaagatccc gctcgagcac tttgtttccg tcatttgaaa
     2581 aatacgggat gcgcaccgtg ccgatttcgt cctctattcc cagcacagag agacggggtt
     2641 gaatcggttc cccggtttct tcatcaatca tgtgcaggtt ccatttctgc tgcccgtccc
     2701 agcgcgagcc cattgtccct tggggtatgg caaatgaact tgtctgttca tcccaaaccg
     2761 caggcttcca ctgatcatgc tttgtcttcc gcccgatgtc cttcgcatgc agaaaccgtc
     2821 ccgctgtgta tacgccattt tcttttgaca gggtgacgag aaatggaaaa tcagtgtatt
     2881 gcttcgcgta ctcaataaaa cgttcagttt cttggttcac gtaaaattcc tgcagaatga
     2941 catgacccat cgccatcgca agcgccccgt cagtcccttg gcgaatactc agccagtcat
     3001 ccgcgaactt tgaggattcc gcaaaatccg gactgatcga aatgacctta gcgcctttat
     3061 agcgggcctc cgccaaaaaa tgcgcgtcag gcgttctcgt taacggaacg ttggagcccc
     3121 atgtgatgat atagccggaa ttgtaccaat cactgctttc cggaacgtcc gtctggtcac
     3181 cccaaatttg cggggatgct ggtggaagat ccgcatacca gtcataaaaa ctgagcatag
     3241 ggcctccgat taacgacata aaccgggagc ctgatgcatg gctgatcatg gacatggccg
     3301 gaatcggaga aaaaccgacg tttctgtcag gcccgtattt catcactgta tacagcagag
     3361 aggctgaaat cagcttcagc acctccggcc attcagcgcg cacaaaaccg cctttccctc
     3421 tcgcctgttt ataggacttc gctttttcag ggttttcgac gatcgatttc caggcgtcca
     3481 atggattttg atgttcttgc agtgcctccc gccataaatt attcagtaca ccgcgcacgt
     3541 atggatattt cacacgcagc gggctgtaga tataccatga aaaactggcc ccccgcgggc
     3601 agcctctcgg ttcaaaatca ggcatatccg ggcctgttga tggataattc aaattttgcc
     3661 cttcccacgt gacaattccg tttttcacat aaatattcca gctgcaagac cctgtacagt
     3721 tgacaccgtg ggtggagcga acgactttgt cgtactgcca tctgtttctg tatacattct
     3781 cccaatcgcg atcttcgcgg gtggtttggc tatgtttatt tgaatggtgt tcgataggag
     3841 agaaataatt caatctccta aacaacggac ttcttttctt tttcttcatg agagttcact
     3901 ccttccgagt caggtgatgc taagttcact ataaacagag acagcgtgtt tccttgtgaa
     3961 ctatgtcaca cactctgctt ttttcacaaa atgttcacac aaaggagaag gaaggctgcg
     4021 ttcaggcaga acgcttgggt cattagccgc ctttcattca aagatcaaaa aaaccggctc
     4081 tatttaagaa ccgggctcag cgttttcatc ctgtgatgta tgcagatacc gcaaaaataa
     4141 ttgataggaa caaaaaacat tttgctgaag catagccaaa aagttcattt gcagctgcgg
     4201 atggtaagac atcattttct taaatatgta atatgggata ttgagaatca gaatgtctga
     4261 agtggcattg actgagataa agggcgataa ataaagcccg cctttttcat caatcggaaa
     4321 cacatcgcct ttttcccaca gcgcaacggt tttcgaccct tcagggagcc tgctgtccac
     4381 gaaacggaca ctgcctttta atacaatata gacagattga gaatgaagaa aagatggaga
     4441 ctgatcacat gagccgcgga taaacgtgcc gtttttcagc aaggtttcga caatggatag
     4501 aggcacttca ttaaacatag gaagttgttt cagaaataat aaatagtcac actgattcat
     4561 aggaaaacct cctgtgctaa ggatagcttt agtgtagctc gactgagcct gtacagcagt
     4621 gatgtatttc acagcctgta tgatgaatgt cacttatcag gagggtgact gcatttataa
     4681 tgaaagaaaa aaggaggatt tctatgaagg cgctgattcc gaagcagcac ggcgcgtggg
     4741 cgatgttgct gatcccattt ttactcggca tggtcaaggg aggccccgtt atttggcata
     4801 ttccgctctt cctaggctgg cttttcctat acttagcggt ttatcccgtt acgcttgcct
     4861 taaaaaagaa acaaagcaaa caatatcaaa agtggatgtg ttattacggt tttcccgcct
     4921 gctgcttttt gatgatctcg gtctttcata agccgcctct catctgggtg ggcgtttctt
     4981 tactgccgct gtttctcata catatgtatt ttgcccgcag aaaaaacgaa cgagccctat
     5041 tgaatgatgt tgcaggtgtc ttgttctttt gttcgggcgg gtttgcgagc tgctggctgg
     5101 ggatgggaac cctcgacggc tgggcttggt ttattttctt gcagtctgct ttatttttta
     5161 tcgggagttc cttttatgtg aaatcggtga ttcgtgaaag aaaaaacagg acatttgcat
     5221 actggtcatg gggatatcac ctgctgctcc cctttttatc cgctcttttc ggagcaggat
     5281 gggcgtttct cgcttttatc ccgagcagct tgcgggcatg gttttttcat ggaagagatt
     5341 ggcccgtaaa aacgattggc attctggaaa tcgtgaatgc ctgcttcttt tttgccgtca
     5401 tgtgcctctt tatgacaagg taaaaaaaca aggacaccgc tgtccttgtt tttttcagtc
     5461 aatattgcaa atctccagcg ggcaattttc acactcaatc tcacatcgta aatagtcccg
     5521 cttgtgcaaa ataatttttc cggattcgtc tatcgaaata accccttttt tgcggagatc
     5581 tcccagcata cggttgatgc tttcccgtgc agccgcacaa aactttgcca aatcctgatt
     5641 tgtcaggaca atgttaatca gaatgccgtc gcttcgcttc actccgtagc tgtttgataa
     5701 gcggataagg gtagaataga gcgccccctt tttgccatga agaagcagat ccctgatttt
     5761 ggactgaatc ttccggaggt gcgtgctcat ccatttcatg aactcaaatg tcaaagcgcc
     5821 gttttggatt aattcttttt ccagcttatt tttattaatg acgagcacct cgccatcctc
     5881 tagcactttt gcactgagca tataccttgg ttcttcagtg aaaagtgtta attctccgac
     5941 gatatcatgc ttttggcaga ttctaagcgt caggtctttt ccatcagatg tcagcttgcc
     6001 gatttcaatg agtcctgatt gaatcagata aagctcttct gcatccattc cttctcgaaa
     6061 caaatacgtg tgtttttcca tttttctttt cgtgctgatc gattccagca attcatgcag
     6121 atcgctggaa ataagatcac tatcagatgg tcgaacagag agaaaattca tgagctcacc
     6181 tcgaagaaag tcacgttgtg tgtttattgt aacgtgaatt gatttgtacc catcgagaaa
     6241 aaactaacaa tcttgtgaat gccccagtgt tagttgatgc tctggctgtt tctctccgtg
     6301 tgtgttttca ttctttcctg ccaatacatc catatgacaa ggacaaaact ggctaacgcc
     6361 acctctgaaa gcgccataaa cccgatcgcg tactggcctg ttgcctgaaa cacactcgcc
     6421 aatatgagcg gaggaaaaaa gccgcctaat ccgcccatgg cagacacaat cccattggca
     6481 atccccgctt gcttggaaaa atagaaaggc accagtttaa aaacagtccc gtttcctatg
     6541 cctgagcaga cagccacggt taatgatcca aacgtataaa ggccaattgt cggcgagaac
     6601 gataggataa tgcctgataa tgtaagcccg gcaaaaacaa acatcaagat gcggagcggg
     6661 ctcattttat cagccaggaa tccgcccgca ggcctgagca gcgtagaaac cgcaataaag
     6721 ccagccgtcc gcaagccggc atctgcagga ttcagcccaa aatgctcgac cagaaagttc
     6781 ggcagataga tagtgaaggc gacaaaggca ccgaacgtaa taaaataaaa caggctcaga
     6841 aaccatagca catgatttcg gtaaacggct ttgatttgag tcttaacaga aactttgacc
     6901 ttcttctcat gcctgtcgcc gaacaaaacg tgcagtaagg caaagacagc cagcaaaacc
     6961 agatacatct gcacggttga tttccacccg acggcttgag cgataaccgg cgctgcaaat
     7021 gtcgtaacgg ctgtcccgat atttcctgca ccgtaaatcc cattgacgac accgtgcttt
     7081 tctttcggat aatatttcgg gagggaggtc actccaatgg aaaacaccgc tcccccgatc
     7141 cctaagaaaa agccgcctgc gattaaatca aacagagagt ccgcgatact gatccaaaat
     7201 acaggaaata aaagcaggat gaagctgacc ataaacatga gccgcgcgcc aaacctgttc
     7261 gttaaatacc ctaaaggaat gcggagaagc gacccgagga tcacaggaat cgccgtcacc
     7321 aaagaaatct cacccttgct taaatgaata tctaatgtga tttgggaaat gagtgatgaa
     7381 atcagcaccc aaaccataaa ccctgccacc aagcttattg actgtaacga taattgaatg
     7441 tgttgacggt tgatcatttg gcttgcccct ttcaatgatt caataatcag tcttatcata
     7501 caaaaactcg gcaaacagga ttgtgaatta catcacacgt ttttctcata aaaaaaggac
     7561 aaagcccgaa gactttgccc ttttgatcgt gattacattt tttccggggc cgatacgccg
     7621 atcagctgaa gcgcattgtt cagcgtaatt tgcgttgcct tcattaaagc caggcgcgcg
     7681 cggctcttct cttcattttc agggtcgatg actttctctg cgttgtagaa gctgtgcaga
     7741 gcagaagcca gatcataaat atagtttgtg acacggtgcg gaattcgttt ttctgctgct
     7801 tccgccactg cctctgggaa gccgccgatc gttttcagca gatcgtattc tttttctgat
     7861 tgaatatggc tgaaatcaag atctgccgcc ggtttaagtt cctgctcttc cccttggcga
     7921 agcatgctgc aaatacgggc atgcgcgtat tgtgcataat acacagggtt ttcgttagat
     7981 gttgatacag caagatctaa gtcaaaatcc atatgggtgt ccgcacttcg cattgcaaag
     8041 aagtaacgaa cggcatccaa gccgacttct tcaatcaggt cacgcatcgt tacggcttta
     8101 ccggtccgtt tgctcatttt cattttctcg ccgtttttgt aaaggtgaac gagctgaatg
     8161 atttctactt caagcgttcc tttttcatag cccagcgctt cgattgccgc tttcatacga
     8221 gggatgtagc cgtggtgatc ggcgccccaa acgttgatca gcttatcaaa gccgcggtca
     8281 agcttgtcct tatgatacgc gatatcagga agcaggtacg tgtacgtgcc gtccttcttg
     8341 atcaatacgc ggtctttatc atcgccgaac gtcgtggaac ggaaccacgt cgcgccgtct
     8401 tcttcataga catggccttt ttcgcggagc gcttcaagcg ccgtgtcgat ttttccattt
     8461 tggtacagtg aagtttcgga ataccacaca tcaaacggca cacggaagtt ttccaagtcc
     8521 ttgcgaagct tgtccagctc gtatttcagg ccgtattcac ggaaaaacgc gaggcgttca
     8581 ctttcctctt cgttaacgaa acggtcaccg tattcctcag cgagacgctt tccgatcgca
     8641 atgatatcct cgccgcggta gccatcctcc ggcatcggtt tttccaatcc gagcgcttca
     8701 aagtaacgga cttcaacaga aagcgccaga ttgttgattt ggtttcccgc atcgttaatg
     8761 tagtattcgc ggcttacatc gtaacccgct tttgaaagca cgttgcacaa ggaatcgccg
     8821 acagccgccc cgcgcgcatg cccgaggtga aggtctcccg tcggattcgc tgatacgaat
     8881 tctacctgaa ctcgttcacc gtttccgatg tttgtttccc cgtatgcttc ccctgcttcc
     8941 agtacagacg gaatcagctt tgttaaatat tgattgttca tatagaaatt gataaaaccc
     9001 gggccggcga tatccagttt ttcaatcgaa gcctttcctt tatcaaaatg agcgacaatc
     9061 tcttcagcga tttgacgcgg cgcttttttt gccactcttg ccagctgcat cgccatattc
     9121 gttgagtagt cgccgtgtgt tttatctttc ggtgtttcta aaacaacatt ggggatctgg
     9181 ctttcttcag ccagtcccgc tttcagaacg gccgctttga tttcttcttt cagcacgtcc
     9241 ttcatttgtt ccgcaatgtt catgcgtgag ttcctccctc atacgtgatc gtcatattat
     9301 gtaaatgctc ctgctcgtct ccgacatgca tgtcatatgc gatgctgata cggccttttt
     9361 cttcatcgag atcagattga atcgattttg tgcttgtttt cagctcaagc tcaccaaatg
     9421 acattttata tttagcaatt gtggaagctc ccgttacgaa acgctgattc attttgacag
     9481 cgcctgacct catgaccagg acttcgcctt cgcttacttt cacaatcgtt ttgactttgc
     9541 ctaagtcgtg ttcttcataa taagatagat acactttatt ttgttttaca tagtaaaatc
     9601 cggtggtgcg gaattcgatg acttcttggt ttccgtcatc ctcgatcaca gacttcacat
     9661 ggagtgttat cggtgtctct tgcttcattc tgacacgtcc ttttcatcat tccactttga
     9721 cttgaatagt ataatcattc ggtttgtaaa cttcaactgc ttctatctta ccatcattgc
     9781 tcatcagatt tgaagataaa cctcataaaa agcatttcct tatatagaag aaaaaatcat
     9841 atcactaatt acctttagga aatgttacat ttttccgaaa tctatcattt ccttttcaca
     9901 tttttttcaa attatatgta ttgaattagt aatttgatag ttttaagata aaagtacaac
     9961 atagatctgc tagaaaaaca aaaaaaggga ggattcaatt atgaaaaaag ctgtcattgt
    10021 agaaaacaaa ggttgtgcaa catgctcgat cggagccgct tgtctagtgg acggtcctat
    10081 ccctgatttt gaaattgccg gtgcaacagg tctattcggt ctatgggggt aaagatctcc
    10141 caaaagggca tagtcattct actatgccct ttttaagtaa attacaattt ttaactaaaa
    10201 tctacctctt ggatatacat acacaaccgt ttttcatttg aatcatatgt ataggggatg
    10261 gtattttgtt tatagagcag atgtttccat ttattaatga aagtgtaaga gttcaccagc
    10321 ttcctgaggg cggcgtgtta gaaatcgact acttgcgcga taatgtctcc atttctgact
    10381 ttgagtattt ggatctcaac aaaacggctt acgagctctg catgcgcatg gatggccaaa
    10441 aaacagctga gcagatttta gctgagcaat gtgcagtgta tgatgaatca ccggaagacc
    10501 ataaagattg gtattacgac atgctcaaca tgctccagaa caagcaggtt attcagcttg
    10561 gaaaccgggc cagccgccat acaatcacca cgagcggaag caatgaattt ccgatgccgc
    10621 tccacgccac ctttgaactg acgcaccgct gtaatttgaa atgcgcccac tgttatttgg
    10681 aaagctcacc tgaagcgctc ggcaccgtgt cgattgagca attcaaaaaa acggctgata
    10741 tgctgtttga taacggtgta ttgacatgcg aaatcacagg cggagaaatt tttgtccatc
    10801 caaacgccaa tgagattctt gactatgtgt gtaaaaagtt caaaaaagtc gctgtcttaa
    10861 caaacggaac actcatgcga aaagagagtt tggagctttt gaaggcttac aagcaaaaaa
    10921 tcatcgtcgg catttctctt gatagtgtca attctgaggt ccatgactcc tttagaggga
    10981 gaaaaggctc ttttgcccaa acttgtaaaa cgataaaatt gttgagtgac cacggtatat
    11041 ttgtcagagt cgccatgtct gtcttcgaaa aaaacatgtg ggaaatccac gatatggccc
    11101 aaaaggttcg ggatctcggg gcgaaggcgt tctcttacaa ttgggttgac gatttcggaa
    11161 gaggcaggga tattgtccat ccaacgaaag acgccgagca gcaccgcaag tttatggaat
    11221 acgagcaaaa tgtgattgat gagtttaaag atctgattcc gattattcct tatgagagaa
    11281 aacgcgcggc aaattgcggc gctggctgga agtccattgt gatcagcccg ttcggcgaag
    11341 tacgtccttg cgccctcttt ccaaaggaat tttcattggg aaatattttt catgattcct
    11401 atgaaagcat ctttaactcc cctctcgtcc ataaactgtg gcaagcgcaa gcgccgcggt
    11461 tcagcgaaca ttgcatgaaa gacaaatgcc cgttcagcgg ctattgcgga ggctgttact
    11521 taaaagggct gaactctaac aaatatcacc ggaaaaacat ttgctcttgg gcgaaaaatg
    11581 aacaattaga agacgtggtc cagcttattt aggagggaaa cgatttgtca ccagcacaaa
    11641 gaagaatttt actgtatatc ctttcattta tctttgtcat cggcgcagtc gtctattttg
    11701 tcaaaagcga ttatctgttt acgctgattt tcattgccat tgccattctg ttcgggatgc
    11761 gcgcgcggaa ggctgactcg cgatgagcat tttggatata cacgatgtat ccgtttggta
    11821 tgaacgggac aacgtcatct tagaacaagt ggatttacat ttagaaaaag gcgccgttta
    11881 cgggttgctt ggggtaaacg gcgccggaaa aacgacactg attaatacgc tgacaggcgt
    11941 gaaccgcaat ttcagcgggc gctttacact gtgcggaatt gaagcggagg ccggcatgcc
    12001 gcagaaaaca tcagatcagc tgaagactca ccgttacttc gccgccgatt atccgctgct
    12061 atttacagaa attacggcga aggactatgt gtctttcgtc cattcgcttt atcaaaagga
    12121 tttttcagag cagcagtttg ccagtttggc cgaggccttt catttttcga aatacatcaa
    12181 caggagaatt tcggagctgt ccttggggaa caggcaaaag gttgtattga tgacaggctt
    12241 attgctgcgc gctcccctgt ttattttgga tgagccgctc gtcggtttgg atgtggaatc
    12301 gatagaggtt ttttatcaga aaatgcgcga gtactgtgaa gcaggcggga ccattttgtt
    12361 ttcttctcat ctgctcgatg tcgtgcaaag attttgtgat tatgcggcta ttcttcacaa
    12421 caaacagatc caaaaggtca ttccgattgg agaggagacc gatctgcggc gggaattttt
    12481 cgaggtgatc ggccatgaat aacataatcc ccatcatgtc tttgctgttc aaacagcttt
    12541 acagccggca agggaaaaag gacgccatcc gcattgccgc aggccttgtc attctggccg
    12601 tgtttgaaat cgggctgatc cgccaggccg gcattgatga atcggtgttg cgcaaaacgt
    12661 atatcatact cgcgcttctc ttaatgaacg catatatggt gtttctttct gtgacatctc
    12721 aatggaagga atcttatatg aaactgagct gcctgctgcc gatttcttca cggagctttt
    12781 ggctcgccca gagtgtcgtt ttgtttgtcg atacctgttt gagaagaact ttattctttt
    12841 ttattttacc gctgttctta tttggaaacg gaacgctgtc aggggcgcaa acattgtttt
    12901 ggctcggcag gttttcgttt tttaccgttt actccattat tttcggagtt gtgctaagca
    12961 accacttcgt caaaaagaag aacttgatgt ttctgctgca tgcggcgata ttcgcctgtg
    13021 tatgtctcag cgccgctttg atgccggccg ccacgcttcc gctttgcgcg gtgcatatgc
    13081 tgtgggcggt gatcattgac tttcctgtct ttctgcaggc gcctccgcag cagggcaaga
    13141 tgcattcatt tatgcggcga tctgaatttt cgttttacaa aagagagtgg aaccgattta
    13201 tctcttctaa agcgatgctg ttaaattacg cggtaatggc ggtattcagc ggcttctttt
    13261 cgttccagat gatgaatacc ggcatcttca atcagcaagt gatttatatc gtgatttccg
    13321 cgcttttgct catctgctcg ccgatcgccc ttttgtactc gattgaaaaa aatgaccgga
    13381 tgctgctcat cacgcttccg atcaagcgga aaatgatgtt ttgggcgaaa tatcgctttt
    13441 attcaggcct attggcaggc ggatttctcc ttgtcgtgat gattgtgggt ttcatcagcg
    13501 gccgtccgat ttcagttctc acttttttgc agtgcattga gttgctgctg gcgggagctt
    13561 ttatcaggtt aactgcggat gaaaaaaggc cctccttcag ctggcagacg gagcagcagc
    13621 tatggagcgg tttctcaaaa tatcggtctt atctgttttg tcttccccta ttcttagcca
    13681 cattagccgg caccgctgta tccttggcgg tcattccgat agccggtctg gtcatagtct
    13741 attacctgca aaaacaggat ggtggtttct ttgatacaag caaaagagaa cggcttggaa
    13801 gttaacctgc tgaagactca tcaattttca actatatcaa tcgccgcgag ctttctgaaa
    13861 ccgatcgaaa gcgcggcgga acctgaggaa gaaacaattt atttttacgg cgccgccgcg
    13921 tacctgaagg agcaaatcat tgacgctttc ggttgtgctg ccggcagccg tttcatgtac
    13981 tcagcgaatc tcttttttga tcagcagctg aaaacctgcg ggacccgttt gattcaccca
    14041 ttatataacg ggaatcttca tgttgacgcc ctgctgaaaa cttttgcaga cttgtctttc
    14101 ccttcttctc tttcattcga agcagttgaa aaggccagga atgagctgct gctgagaatc
    14161 gaaaagaaat tcactgatcc cttctcctac tcggcggcgc gcttggctga ggaggtcttc
    14221 ggaaacccga tgtacggcac aggcatgttt ggccggagag acaggataaa ggcgattcat
    14281 cctaaacggt ttctcgacgc aacggacttt atcgttgatt tagtgtccca gcaaaaacag
    14341 ctgaacatat tgggacaagt acaagcatgt gatgttcggg gacatgcccc gcaaacgtcc
    14401 gctgtaacgt ccggaagaat acccgtaaac cggcatgttt ttgaaacaga gacacgcagc
    14461 gctgcaggtc cttccgtctt gacactcgga tttgactgcg gagagatgaa agatgccagc
    14521 gattatatca aaatacagct aatagacgga ttactgggaa agtacggcca ttccgcttta
    14581 ttcaagcact tcagagagaa ggatctggca gtctatcacg ttatcacccg ttacgatgtc
    14641 atgaacaatt tgctgcttgt ttcaatatgt acagatcagc ttcatgagaa agacattccc
    14701 ccgcgcgttt tggaagctgt ctcagctttt catacagatg agcgggaact agaacaggca
    14761 aagcagtttt tacgcaatga attgctgctg caattcgatt ctcccgaagg tctattggcc
    14821 tatatgggga tcctgcgccg cttctcctgc acgaaagaag ccttgctgga tggcatctca
    14881 gcggttacat gccgtgatgt attgcaattc atagcgacca tcaattatat cggagctcat
    14941 gtagtaaggg gatgaagaga tggaaaagaa agcctttttt caacaactgg atgaacgaac
    15001 cgatatcaga tacacagaca gcggactaaa aatattcaga ttgaaattcc cccgcgccca
    15061 cctgcggctg tgcaatgtaa aaatcgattt tggaagccgg gatgtatgta tacgggcaga
    15121 atccggtgat acactgcttc cgtatggcac agcgcatttt ttagagcatc ttctcttctg
    15181 gcataacggc cgcaatctgt acagtgattt ttttgcgcat ggcgcgcttt taaacgcatt
    15241 cactacctac accgatacca atttcatgtt tacctcatta ccggatcggc tcagacaaac
    15301 gatccccatc ctgcttgatg ctttatggaa ccactcattt gacaagaaga ttgtcgctca
    15361 ggaaaaagct gtgattacaa gcgaaattca aacagcacac cttaaccatc agctctcata
    15421 tcattatcag ctgatcagca tgctttctcc ctcctcacca gctgccgttt tccccgcagg
    15481 cagaatcgaa gatattgagg cgctggacat caatgattta caaaaagcct ataaggctgc
    15541 ctaccaagcc catcggatga cactgttttt gattgggggc tcagaaaata cagaaacgct
    15601 tttgcctcct cacctccagc tggaaaagcg tccggattat catgctgaaa gaaaaatcat
    15661 cccggcatgc cctccagccc tctcacaaaa aatggtgctg ggtgatgagg agcggatgga
    15721 agatacctgg accggattac agatcggcgc acttcccggg caaaacgatc tgttgtcgat
    15781 aaagctttat tgggatatcg cggctcgtat tctatttcaa ttagattcac cattttttca
    15841 agagattcag caaacgtacc gtctggaaat cgatcgcttg tcagccgaga cttatatata
    15901 tgaggatggc ggtttcttga tccttcacag tcaagggacc cattcttcag cttatatcga
    15961 tgtggcttca tactatgtca cacagaagaa agaacaggtt gccgcctggc ttcaatacgg
    16021 caaggactct ttgacagacg cgatcattta tgacagcgat tatgtgcgta aatgcttcga
    16081 gtgggcagcc gagtgtgaca ggtgcgattg ctcgtttctt gacatgtacc acatcattca
    16141 agatatggat gcgcaggttt tcttgtctct cattgatgca atggcatctt ctaacaaagc
    16201 gatcattcac gtttctcaga aagaggcgat cagacaatga aaaaaagcac tgtctttacc
    16261 cttttattgc tgcttatagg tatggcggct tattccttcg gctgggttca ggccgtggcc
    16321 gaagccgccg cccaatatgt acagatgatc aacaatgacg ctgagcggct cgggctgctg
    16381 gcttgtaccg ctgccctcct gatgctgcct gcttttctct atcttcacta tgtcacccaa
    16441 tccgtgaaaa acatgacagc agcttttcag aaactcacac agtctcatca aagctgctgt
    16501 gactttcagc aacacaactt gtgcagccga tatgcagaag acgtcaaatc gctgcgtgac
    16561 agctataaaa acgtccgcca aacatacgtg atggctgccg tgttgtgcca agtcttcata
    16621 ttcggctgca tgttcgaaat cgttaaagcc gtccctttcc gccttcatac gccccctgcc
    16681 ttttcaatgg gacttgcgat gctactgatc ctgtatttat tgttttgcat gcgaacgtat
    16741 ttgcggcagc ttttccggca cggcagcctg ttcagaaaag tgtttgcggg agtgctggca
    16801 gcagccggga tttggtggat gctcagtttc tctataagtg aactgctgtt tctgattatc
    16861 ctggctgcca ttcagcaaat cggatcattt atttataaac gattctctta tcgcagcacc
    16921 gcttctcttg atctataaaa tagctacatc gcaatcgcag acggacccgc gccaaccgga
    16981 atcaccgtca cggctgtata atcacttgtg cggtacacgg tcacagcatt gtcgttgggc
    17041 tgtgccgcat aaatatactg tttgtccggc gttacggcga ggtcaaaggc gccggggaga
    17101 gacacgtttg caatgatcct ctgtctggcc gtattaacta catataagtt attaatgaga
    17161 aacggttcac tatatggctc tagaaaataa gctctagtac tatcgagaga aaatacaatc
    17221 gtcatcagcg tttcaaataa acggctgaag tcccctcccc tgcttaatgg agacaaacta
    17281 atctccgtta cacctttcgg ccacagctca ccatttaaca cgtacgcaaa atttccagcg
    17341 taaggagtcg caattaaact gggaaattca aatgaatcta tgatactttc taccaactgc
    17401 ccagtattta catcatattt atcaaccgac caactgcttc cattagcggt atagacatac
    17461 tgtccattcg gatcaagagc aaagtctaaa gcgccgggta tcggaatgac atcaatgacc
    17521 gattgagagg ccgtgttaat cacatatata gatccggcgg ccatcacgta tgcgaactca
    17581 tctgttggat caaattcgat ttttctcggc cctcctccaa cagtaatggt atttatgata
    17641 gttaatgttt tattatcaat cactgagaca aggttggtat ttccatggag gatatacgtg
    17701 aatgctttat cgaaagtaac gcctagatta gttggcacag cagaaaacgg gattgttttt
    17761 acaacagtgt ttaaatctgc atcaatgacc gaaaccgtgc tgtctccagt attggcagta
    17821 aacacatatg attgagggtc tggcgatggc ggtaaaacaa gtgtcccggc caccgtaagc
    17881 ggactgccgt agaaaggcgg tacaatgaga agatcttcca ctttcatttg actaaaatca
    17941 ggacagcggt cagactgtgc tgcataataa acaacttgat caatctcttc ggtatgaatc
    18001 accgaaacag ccccgtctcc ttgtccatat tgatttcgta caggcgacac actgacaaga
    18061 agcgtaatgg tcccttgtac tctcacggca tatcgaacac cgatatcttc tggttccggc
    18121 ccagtctgga ttaagcaagg ctcactgata caggacaaat tgtctgtact ccatgtaaca
    18181 gccgctgacg cttctgccga atcaaccttg aagccctcag ggatatctat cggcacttga
    18241 aacggcgctt cccggctaat ttcctcatca caaaaacaga aacaattttc ctgtaaagca
    18301 gaaagatcat tctttttcat gatttcacgt ccttttagaa atgcacaaca tgcagcggtt
    18361 aaatcgtaat ggcacccggt gaaaccccaa gagatatcac agtttcctca gaataatcat
    18421 ctgtgttgta aacaatgatg ctctgctcta taaaacgagt tgcatacaga aaatcgccat
    18481 tcggggtaaa cgcatagtct gttgctgatt gcggaagatt tccaattaca cctgctccat
    18541 tcggactgac agaatataaa ttgccagtga agctgtcatg taaatacacc tctgatccac
    18601 tcgtaaacat tacatatagc ccgtcaggct ccagctcttg ggtatccctg atcgtaaacg
    18661 tatttaaatc aataaccgtc aaataattga ataagaattc ttgttctaat acatacgcat
    18721 accgctccgt agaatctgtt tctatggatg atacgataag ctctcgttca atcgttccta
    18781 agacttcacc ggtagataag tccacttttt gcactaaccc aaaattaaga acataggcga
    18841 acaacccatt ggggtcaatt gcaatatcaa aaccttctac aggaatagac ctctcaacag
    18901 tcaacgtatc aattccaatc acataaatgg cagtaccggc gaaaacataa gcaaactcat
    18961 gattagggat aaatctaatc aatcgaggcg gctgatccag caatatagtt gctgtcactg
    19021 ttaatgtgtc ataatcgatg acagaaatca cattattgtt gggatgtaag acaaacacag
    19081 cgcttttatc tggcgtaatt tcaatacctg ccggattgta cggaagagca atcgttgtca
    19141 caacagtatg ggtgtttgta tcaatcacag aaactgattg atcatttgga ttcgctgtaa
    19201 acgcgtagac gggttccggc tccggtacaa gcacaatcgt ccccgtcacc gataaaggac
    19261 tgccgtaaaa cggcggaaca acaacaaggt tctcaatcgt gatgtcactg atatccgggc
    19321 aatcatccgg ttcatcggaa taatagacga cttgatcgat ttctgcattg tgaatgacgg
    19381 aaacagcccc gtccccttgt ccatattgat ttcgcacagg tgagacactg acgagtagcg
    19441 taacggttcc ctgcaggcgc actgcaaatt gaacaccgac ctcatcaggc tctggccccg
    19501 tttgaattaa gcaacggtca ctgacacaag aaaggctgtc tgcattccac gtcacgtttg
    19561 caacagcttc agccggatca acgacaaatc cttcaggtaa ttcaatcggc gcttgaaaca
    19621 tggcttctcg gcttgcttct ccctcacaaa aacataagca ctcttcttgt tctgctcctg
    19681 ctttttcttt aaaggaaagc ttattttttc tcattccttc acttcctttt cagacataca
    19741 ctgctcacgc agatataaca gaatatggaa gattaacgtg tttgcttgta caaattgctg
    19801 agggtaaacg cttctttttg aaaagatatc tccaaacatg cggtgtaacg aaagaaaaaa
    19861 ttgcggtttt tttgcgcttc tcacaagaat gttgatgata aaatatgaca tatatagaat
    19921 tatgaaggga gggatttgca aacgtgacag gtgtcatatc ttcttcttcc atcggagaaa
    19981 agattaacga atggtatatg tacatacgcc gattcagcat acccgatgca gagtatttgc
    20041 gaagagaaat caaacaagag ctggatcaaa tggaagaaga tcaggatctt catttgtact
    20101 attcactgat ggagtttcgg cacaacctaa tgcttgagta ccttgaaccg ttagaaaaaa
    20161 tgaggattga ggaacagccg agactgtctg atctgctgct tgagattgat aaaaaacagg
    20221 ctcgtttaac tggtctgctt gagtactatt ttaatttctt cagaggcatg tacgagctgg
    20281 accagcggga atatctgtcg gctattaaat ttttcaaaaa ggccgaaagc aagctgatat
    20341 tcgttaagga tcggatagag aaagctgagt ttttctttaa gatgtctgaa tcttattact
    20401 atatgaaaca aacgtatttt tcaatggact atgcacggca agcatatgaa atatacaaag
    20461 aaaatgaagc ttataatata agattgctgc agtgtcattc tttatttgcc accaattttt
    20521 tagatttaaa acagtatgag gatgccatct cacattttca aaaagcttat tctatggcag
    20581 aagctgaaaa gcagccccaa ttaatgggaa gaactttgta caatatcggg ctttgtaaaa
    20641 acagccaaag ccaatatgag gatgccatac cttatttcaa aagagcaata gctgtttttg
    20701 aagaatcaaa tattcttcct tccttacctc aagcgtattt tttaattaca cagatccatt
    20761 ataaattagg aaaaatggat aaagctcatg aatatcatag taagggaatg gcttattcac
    20821 aaaaggccga agatgtaata tatttatcag agtttgaatt tttgaaatct ttatacttat
    20881 caggcccgga tgaagaagca attcaaggat tttttgattt tctcgaaagt aaaatgttgt
    20941 atgctgatct tgaagatttc gctattgatg tggcaaaata ttatcatgaa cgtaaaaatt
    21001 ttcaaaaagc ttctgcttat tttttgaagg tggaacaagt aaggcaactt attcaaggag
    21061 gagtgagttt gtatgaaatt gaagtctaaa ctattactct cttgtctggc tctaagcact
    21121 gtgttcgtgg caacaactat tgcaaatgca cctacacacc aaattgaagt tgcacaacga
    21181 ggaatgattt aatgaataca accggttttc accggttgtt tttttgttaa ataaacaatc
    21241 gggacaaaag ttttattttt tgaatctcta aatattatta ctaactaatt caaattggtt
    21301 acctaaccca caaacatagg aaacaagata atttttatta tacgaaaata aaaatatgtt
    21361 tacttttcct tttttttgaa ctaatatata tatatgactt aagttcagta tcacttcaat
    21421 tgaagtttaa aaatggagga tttattttga aagttcaatt caaaaaaagg attagtttac
    21481 tcatcatcat gtttgggatc gcagtttcct cactgggtgt tacacaggcg gttcatgcaa
    21541 aagcaaatac gagcgattca agggtgcatt ttactttcag atggtacagc ccttacgact
    21601 atacaactgc tc
//
