LOCUS       NZ_CP060193            12184 bp    DNA     circular CON 06-NOV-2024
DEFINITION  Bacillus sp. PAMC26543 chromosome, complete genome.
ACCESSION   NZ_CP060193
VERSION     NZ_CP060193.1
KEYWORDS    RefSeq.
SOURCE      Bacillus sp. PAMC26543
  ORGANISM  Bacillus sp. PAMC26543
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
            Bacillus.
REFERENCE   1  (bases 1 to 4101852)
  AUTHORS   Park,H.
  TITLE     Complete genome of Bacillus sp. PAMC26543
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4101852)
  AUTHORS   Park,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2020) Division of Biotechnology, Korea University,
            145 Anam-Ro, Seongbuk-Gu, Seoul 02841, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: JAN-2020
            Assembly Method                   :: HGAP v. 4
            Assembly Name                     :: KU26543
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014250375.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 07:02:54
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,183
            CDSs (total)                      :: 4,061
            Genes (coding)                    :: 3,892
            CDSs (with protein)               :: 3,892
            Genes (RNA)                       :: 122
            rRNAs                             :: 10, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 169
            CDSs (without protein)            :: 169
            Pseudo Genes (ambiguous residues) :: 0 of 169
            Pseudo Genes (frameshifted)       :: 124 of 169
            Pseudo Genes (incomplete)         :: 63 of 169
            Pseudo Genes (internal stop)      :: 21 of 169
            Pseudo Genes (multiple problems)  :: 32 of 169
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:43:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 163068
            Orig. end                         :: 175252
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP060193.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Hyun Park.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..12184
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..12184
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..12184
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:7184](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..7184)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            41..466
                     /locus_tag="H7F27_RS00865"
                     /old_locus_tag="H7F27_00865"
     CDS             41..466
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003242533.1"
                     /locus_tag="H7F27_RS00865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H7F27_00865"
                     /product="DUF5391 family protein"
                     /protein_id="WP_185848414.1"
                     /transl_table=11
                     /translation="MSRKNRVVIMTAISAFLFCAMIAAASLSPLADTGSSANQFNSIGM
                     WSAIGMILVFYLIPILIYMLGVDAMRYVMAALCGMGLLIHLSTAAIVLMVSIFSDHPLS
                     DVITVMGLCLASAAVNIIWFFAAFRSAPKKPVTRDFT"
     gene            complement(589..1926)
                     /locus_tag="H7F27_RS00870"
                     /old_locus_tag="H7F27_00870"
     CDS             complement(589..1926)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391865.2"
                     /locus_tag="H7F27_RS00870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H7F27_00870"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_185848415.1"
                     /sec_met_domain="Aldedh (E-value: 4.6e-98, bitscore: 326.6,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQQVKDDIQRVFQLQKKQQKVLRASTAEQRKEKLQRFLDSVIAH
                     EEEIIEAIRKDVRKPYHEVKKAEIEGTKKAIRDNINNLETWMAPKEVGSSLSSDANGIL
                     MYEPKGVTLILGPWNYPFMLTMAPLAASIAAGNSAIVKLSDFTMNTSNIAAKVIRDAFD
                     EKEVAIFEGEVEVATELLDQPFDHIFFTGSTNVGKIVMTAAAKHLSSVTLELGGKSPTI
                     IDSEYDLMDAAKKIAVGKFVNAGQTCIAPDYIFIKKDVQDKFAGILQTIVNAGFMEDDY
                     TPDRNKFTQIVNDRNFNRVKALYDDAIEKGAEVVFGGVFDASDRTISPTVLKNVTPDMK
                     IMQEEIFAPILPMMNYEDIDEVIDYVNDRDKPLALYVFSHNQDLIDNVLQHTTSGNAAI
                     NDVVVHFSDINLPFGGVNTSGIGSYHGVYGFKEFSHEKGVFIQAAK"
     gene            2068..3210
                     /locus_tag="H7F27_RS00875"
                     /old_locus_tag="H7F27_00875"
     CDS             2068..3210
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391864.1"
                     /locus_tag="H7F27_RS00875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H7F27_00875"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_185848416.1"
                     /transl_table=11
                     /translation="MPESAEAQIKQALLDLLEKRDIRQITMKEIAEHAQVSRGTLYLYY
                     EDKFSIIEDVIVDMKEGLGEALYNAFKHIDTFHLNKKRHTVHPTLSFVHEHRSFFGTMM
                     NRGQFHRFFKDVFQQDVLLAPIHVNLTPIEREIYGHYRALYTYAIILYWLNEDAEASPE
                     AISQKVWELVSQKRFYWLFGQAPSWERQEDKQIDRRVVRTREALQKALLDVLSEKKDYA
                     AITISDITRKSNIRRATFYDHYASKEELLQTIIQQACAEIIDHLSIAFSPNELSLEEAR
                     EALASLLSALDRMPIVHLLNRDWSVPHVIPEMLKALESFYLHQQTNIPAEKKLYAYYVS
                     AMIIGLILYRLDEGKAYAPEVLTREFLQFLDVKKYKVVLL"
     misc_feature    complement(2094..2107)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 20.38"
                     /tool="antismash"
     gene            complement(3531..5000)
                     /locus_tag="H7F27_RS00880"
                     /old_locus_tag="H7F27_00880"
     CDS             complement(3531..5000)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1029: RND family
                     efflux transporter MFP subunit"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014481437.1"
                     /locus_tag="H7F27_RS00880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H7F27_00880"
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="WP_024123466.1"
                     /transl_table=11
                     /translation="MKRNFFNLNDLRDSREFYESKPKPIGVFFTYILIALLIACIVFSF
                     YGKKEVILKTTADIQYTKPNSNVTNEVAGKVKTVDIKQVDKVKKGDTLLTLDNTEIQAQ
                     KKAVKEDIKDLKEQAALNKTLKKSIENDKNLFSENDHWGYQDQYLSYEKQSNLLESSKE
                     NAKTQQKKLKKQKISIKNSLDKTKNKVKLKLQRISDLQDSIKNNKSFAKQDDKYNSYYN
                     SYQTNKQNVEQQLDDLRKMKDGLDKNSFSQQKENLNGQLESLKQDMLVKLSEEKDELNQ
                     SLDEINSSMKSDDSDSDSDNSEETNYKLSIEQLKTNLLNQTSQKQTDLQTTLKSKEDDL
                     KMIDLQLEKYKIKATSDGYVNVLTNISPGDNLQAGTAILTIVPDKEKLRANIYIPSHEI
                     TNINEKDEVRFHIENTNQTIKGVIIKISPDSISDQNGQKFYIAESKIESKEIVKNNGTK
                     IHLKNGMQTDVSIIVDSKRYIDYFLDTLNLH"
     gene            complement(5001..7184)
                     /locus_tag="H7F27_RS00885"
                     /old_locus_tag="H7F27_00885"
     CDS             complement(5001..7184)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014481436.1"
                     /locus_tag="H7F27_RS00885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H7F27_00885"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_024123465.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 8.2e-43, bitscore:
                     143.3, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 2.3e-236, bitscore:
                     784.4, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFFNRYHCVRQLDQKDCGAACLSTIAKHYGSKLSLAYIRDIAGTD
                     TQGTSALGMVKAAEQLGFSAKAVRAEHTAFDQSITLPAIAHIIIDQQLLHYVVIHKISK
                     DKIIIADPGKGLVTYQKDDFFKIWTGILILLAPTETYKKQTETSNISADIFRLILQQKS
                     LIIHTFLASFIITVFGILGTFYFQTIIDQILPNGLSNTLHILSIGLLIMYLFKVFLIGF
                     RQYLMILLGQKLSISIMFGYFQHVLTLPMKFFSNRKVGEIISRFTDANKVIDAVVSASL
                     SVILDTIMLIMVGIFLYLQNTTLFLITLAFIPFYILTVWIFIKPYENINNTEMENNAQL
                     TSKIVETLNGIETVKAYNAEYMMSFETEKRFVKYLRSAFKHGVIDNLQSSIKMFLDLAS
                     GALILWIGSTQVMKGTLTIGQLITYNALLTYFLNPLQNIIGLQSKLQSASVASKRLGEI
                     LKLEPELIEKEARITSTSSITGPLSFKKINFRYGTRRLILKDITLHIQKGEKVAFVGES
                     GSGKSTLTKLLMKFYTAESGEVSINGYHINDIHINALRESISYIPQESHFIQGSILENL
                     LLGNSGSFTFEEIIEVCKQTKVHDFINDLPMRYDTLVEENGSNLSGGQKQRLAIARALL
                     RKPNILIMDESTSNLDTTTEQGISKMIYDQTVDVTTIIIAHRLSTIMNCDKIFVMENGE
                     IIEYGNHNDLLKKKGKYYELWENQMPSREMVTI"
     misc_feature    complement(7382..7397)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.73"
                     /tool="antismash"
     gene            7596..7814
                     /locus_tag="H7F27_RS00890"
                     /old_locus_tag="H7F27_00890"
     CDS             7596..7814
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018664240.1"
                     /locus_tag="H7F27_RS00890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H7F27_00890"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_024123463.1"
                     /transl_table=11
                     /translation="MNNNLKLERTRANLTQEQLAEKIGVTRQTIGLIEKGKYNPSLQLC
                     LKICIELKVTLNDVFWTHNREEETNEG"
     gene            7804..8229
                     /locus_tag="H7F27_RS00895"
                     /old_locus_tag="H7F27_00895"
     CDS             7804..8229
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042802.3"
                     /locus_tag="H7F27_RS00895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H7F27_00895"
                     /product="DUF6773 family protein"
                     /protein_id="WP_024123462.1"
                     /transl_table=11
                     /translation="MKDERISHIENKIGHESFLLVIALVFVSFILSIMFKMPSTLMTII
                     ILFVGSGYYGLRAMLKGILRVNLKKKKKSSYFLLIVFTFILYMATSVLFKIITFPFTTK
                     EFLFQILMYILWLIPFSLIMYTTYKFSNRQQKKELEN"
     misc_feature    complement(8230..8248)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 26.61"
                     /tool="antismash"
     misc_feature    8258..8276
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 24.61"
                     /tool="antismash"
     gene            8422..8652
                     /locus_tag="H7F27_RS00900"
                     /old_locus_tag="H7F27_00900"
     CDS             8422..8652
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H7F27_RS00900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H7F27_00900"
                     /product="hypothetical protein"
                     /protein_id="WP_024123461.1"
                     /transl_table=11
                     /translation="MNAKSIKDVELQALTLEEAEQIDGGSYAKYLGSAVVTGAGAGVVG
                     GVPGVILGAHAGAIAGSVGYLGGSLIAGKWL"
     gene            8669..8893
                     /locus_tag="H7F27_RS00905"
                     /old_locus_tag="H7F27_00905"
     CDS             8669..8893
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H7F27_RS00905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H7F27_00905"
                     /product="Blp family class II bacteriocin"
                     /protein_id="WP_024123460.1"
                     /transl_table=11
                     /translation="MENNNRLSELNVKEMEQIDGGGWRSALGGAFSGALVGASTVGVGG
                     AAVGGPVGGAGGAITGGIVGGIVGGINAW"
     gene            complement(9041..9862)
                     /locus_tag="H7F27_RS00910"
                     /old_locus_tag="H7F27_00910"
     CDS             complement(9041..9862)
                     /NRPS_PKS="Domain: PKS_KR (7-160). E-value: 6.5e-10. Score:
                     31.1. Matches aSDomain:
                     nrpspksdomains_H7F27_RS00910_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391863.2"
                     /locus_tag="H7F27_RS00910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H7F27_00910"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_185848417.1"
                     /sec_met_domain="adh_short (E-value: 1.5e-32, bitscore:
                     110.9, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 3.3e-38, bitscore:
                     129.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRLDNKTAVITGAATGIGQATAEVFANEGARVIFGDMNEDQMKE
                     TVEAIRQNGGQAEAFHLDVSDEENVKQFADQLKDAYGTIDILFNNAGVDQEGGKVHEYP
                     VDLFDRIIAVDLRGTFLCSKYLIPLMLEKGGSIINTSSMSGRAADLDRSGYNAAKGGIT
                     NLTRAMAIDYARNGIRVNSISPGTIETPLIDKLAGTKEQEMGEKFREANKWITPLGRLG
                     KPKEMATVALFLASDDSSYVTGEDITADGGIMAYTWPGKMLIDEKWKEETK"
     aSDomain        complement(9383..9841)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_H7F27_RS00910_PKS_KR.1"
                     /evalue="6.50E-10"
                     /label="H7F27_RS00910_PKS_KR.1"
                     /locus_tag="H7F27_RS00910"
                     /protein_end="160"
                     /protein_start="7"
                     /score="31.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TAVITGAATGIGQATAEVFANEGARVIFGDMNEDQMKETVEAIRQ
                     NGGQAEAFHLDVSDEENVKQFADQLKDAYGTIDILFNNAGVDQEGGKVHEYPVDLFDRI
                     IAVDLRGTFLCSKYLIPLMLEKGGSIINTSSMSGRAADLDRSGYNAAKG"
     CDS_motif       complement(9764..9835)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_H7F27_RS00910_0001"
                     /evalue="3.60E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="H7F27_RS00910"
                     /protein_end="33"
                     /protein_start="9"
                     /score="16.4"
                     /tool="antismash"
                     /translation="VITGAATGIGQATAEVFANEGARV"
     gene            9981..10232
                     /locus_tag="H7F27_RS00915"
                     /old_locus_tag="H7F27_00915"
     CDS             9981..10232
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391862.1"
                     /locus_tag="H7F27_RS00915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H7F27_00915"
                     /product="hypothetical protein"
                     /protein_id="WP_024123458.1"
                     /transl_table=11
                     /translation="MKIQHKKELKFYCLITIPAAFAVLTVISFLLQEITFPVTASAFLN
                     ASWHNLLFLIPFCLFFYPVHIWMKREFSRWNDAGQKRG"
     misc_feature    11472..11487
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 20.91"
                     /tool="antismash"
     misc_feature    complement(12046..12061)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.72"
                     /tool="antismash"
ORIGIN
        1 taaaggttaa tatttctatt ttaggaggtg tcaattgatc atgtccagaa aaaatcgcgt
       61 ggtgatcatg actgcgattt ctgcattcct tttttgcgct atgattgctg cggcttcact
      121 ttctccgctg gcagacacgg ggtcctcagc caatcagttc aactctatcg gtatgtggtc
      181 ggcaattggt atgatacttg ttttctatct cattcctatc ctcatttaca tgctgggtgt
      241 ggatgcaatg agatatgtga tggcggcgct ttgcggcatg ggtttgctga ttcacttatc
      301 tactgccgcc attgtgctga tggtcagtat attcagtgac catccgctct ctgatgtgat
      361 cactgtgatg ggactctgtc tcgcttcagc ggctgtaaac atcatttggt tttttgcagc
      421 gtttcgttct gcgccaaaga aacctgtcac aagggatttt acatagtttt ctattttgtg
      481 ttaatgcatg atttttctgt gaactatatt tatttattgt tatgaaactt tgtcggggat
      541 gatagaaaaa gagaacctgc aagatgatgc agattctcta aatcatgttt atttagctgc
      601 ttgaataaac acaccttttt catgagaaaa ctctttaaat ccgtataccc catggtaaga
      661 gccgattccg cttgtattta cgccgccgaa tggcaggttg atgtcactga aatgaacgac
      721 gacatcattg atcgctgcat ttcctgatgt ggtgtgctga aggacgttgt cgatcaggtc
      781 ttggttgtgg ctgaatacat aaagcgcgag cggtttatcg cggtcattta cgtaatcaat
      841 gacttcatcg atgtcttcat agttcatcat cggcaggatc ggtgcaaaga tttcttcctg
      901 catgatcttc atatctggcg taacgttttt caaaacggtt ggcgagatcg tacggtcgct
      961 tgcatcaaat acgccgccga acacgacttc cgcgcctttc tcgatggcat cgtcgtataa
     1021 agctttgacg cggttaaagt tgcggtcatt gacaatttgc gtaaatttgt ttcgatccgg
     1081 cgtgtaatca tcttccataa atcctgcgtt gacaatggtt tgtaaaatgc ctgcgaactt
     1141 atcctgcacg tcttttttaa tgaagatata atccggtgcg atgcaggttt ggccggcatt
     1201 tacgaacttg ccgacagcaa tttttttcgc tgcgtccatt aagtcgtatt cactgtcgat
     1261 gatggtcgga ctcttgccgc caagctcaag cgtgacagat gacaagtgtt tggcggcggc
     1321 tgtcatgacg atttttccga catttgtgct tccggtgaag aaaatgtggt cgaacggctg
     1381 atcaagaagt tcagtggcca cttcaacctc tccttcaaaa atggcaactt ctttttcgtc
     1441 aaaagcatct cggatgactt ttgcggcaat attgctcgtg ttcatcgtaa agtctgacag
     1501 cttcacaatg gcgctgtttc ctgcagcgat agaagcggca agcggcgcca tcgtcagcat
     1561 aaacgggtag ttccacggac cgagtataag cgtgacgcct ttaggctcgt acataaggat
     1621 tccgttggca tcagagctta aggatgaacc gacttctttg ggtgccatcc atgtttccag
     1681 gttgtttata ttatctctga tcgctttttt tgtaccctcg atttccgctt ttttgacctc
     1741 gtgatatggc ttccgcacgt ctttgcggat cgcttcgatg atttcctctt catgtgcaat
     1801 gacggaatcc aaaaagcgct gaagcttttc tttccgctgt tccgctgttg aagcgcgcag
     1861 cactttttgc tgttttttct gaagctggaa gacgcgctga atgtcgtctt ttacttgctg
     1921 ttccattgta aaatccccct catttgcttt ctgcttatct cggaactatt ataaagtggt
     1981 atcttttcta taagaaagac aacggagaat catctatacg ttaccgtaca tatatcgaac
     2041 atctgtctaa gtttggaggt gactcttttg ccggaatctg ctgaggctca aatcaaacag
     2101 gcgcttctgg atttattaga aaaaagggat attcgacaga ttacaatgaa agaaattgct
     2161 gaacacgcac aagtgagccg cgggacactc tatctttatt atgaagacaa gttctccatt
     2221 attgaggatg taatcgtaga catgaaggaa ggtctgggcg aggcgctcta taacgccttc
     2281 aagcatatag acacattcca tttaaataaa aagcggcaca ccgtgcatcc gactttgtct
     2341 tttgtccacg agcatcgatc cttttttggc acgatgatga acagaggaca gtttcatcgt
     2401 ttttttaagg atgtgtttca gcaggatgtg ttgctggcac cgattcatgt gaatttgacg
     2461 ccgatcgaac gggaaattta cggacattac cgggccttgt acacgtacgc gattatcctg
     2521 tattggctga atgaggatgc ggaggcgtct ccggaagcca tcagccaaaa agtatgggag
     2581 ctcgtttctc aaaagcggtt ttattggctg tttggacagg ctccgtcatg ggagcggcag
     2641 gaggacaagc aaatcgacag gcgtgtggtt cgaacgagag aagcgctgca gaaggctttg
     2701 ctggacgtat tgtcagagaa aaaagactac gcggccatca cgatttctga cattacccgg
     2761 aaaagcaata tccgccgcgc aaccttttat gatcactatg ccagtaaaga agaattgctg
     2821 cagaccatca ttcagcaagc gtgtgcggag atcatagatc acctgtcgat tgccttcagt
     2881 ccgaatgagc tttctttaga ggaagcgagg gaggcgctcg ccagcctgct ttctgcttta
     2941 gaccgcatgc ctattgtcca tttgctcaat cgggactgga gtgttcctca tgtgataccc
     3001 gagatgctca aagcgttgga atcattttat ctgcatcagc aaactaatat tcctgcggag
     3061 aaaaagcttt atgcctatta tgtatcggcg atgattatcg ggctgatatt gtatcggctc
     3121 gatgaaggga aggcgtatgc gccggaagtg ctgacgaggg agtttttgca gtttttggat
     3181 gtgaagaagt ataaggttgt attgctttga agtgcccgga gacttaatcc gggctttagg
     3241 tcgttatgat acttggtctt ttgattttct ttcttttaag gtgagattga gaaatagaag
     3301 agacaaaaga ataaaaacaa tattcaccgt ccaagacttc cagcttacag tggggaacaa
     3361 tactgtatta aagaaaaggc gaacgattga agagaataaa aagagtaaaa ataacagttt
     3421 gttttgaaac atgattctat acgtcctcta cctttcttaa aaaaataaaa tgcctcaaag
     3481 cagatgctca tctgctttga ggcatatatg cacacttctc ttgatgggaa ttaatgtaag
     3541 tttaatgtat ctaaaaaata atcaatatat ctttttgaat caacaataat agatacatca
     3601 gtctgcatgc cattttttaa gtgtattttt gttccgttat ttttaactat ttctttgctt
     3661 tctattttgc tttcagcaat ataaaatttt tgcccatttt gatcactaat actgtctgga
     3721 cttattttga taatgacacc tttaatggtt tgatttgtat tttcaatatg gaatcttact
     3781 tcatcttttt cattaatatt tgtgatctca tgactcggaa tataaatgtt agctctaagc
     3841 ttctctttat cagggacaat agtcaaaata gcagtgcctg cttgtaaatt gtcacctgga
     3901 gatatatttg ttagtacatt aacatagccg tcactagttg cttttatttt atatttttct
     3961 aattgtaaat ctatcatctt tagatcatct tcttttgatt taagagtggt ctgaagatct
     4021 gtttgctttt gagatgtttg atttagcaag tttgttttaa gctgttcaat tgaaagctta
     4081 taatttgttt cctctgagtt atcggaatca ctgtcagaat cgtcactttt cattgaactg
     4141 ttaatctcat caagtgattg atttaattcg tctttttctt cacttagttt tactagcata
     4201 tcttgtttta aactttcaag ctgtccgttt agattctctt tctgctgtga gaaactgttt
     4261 ttatcgagcc catctttcat cttccgtaga tcatcaagct gctgctctac attttgtttg
     4321 ttagtttgat aactattata gtaagaattg tacttatcat cctgtttggc aaaggattta
     4381 ttgtttttaa tggagtcttg cagatcagaa attctttgaa gctttagttt cactttgttt
     4441 tttgtcttat ccagactatt ttttatgctt attttctgct tcttaagttt tttttgctga
     4501 gtttttgcat tttcttttga tgactctaac aaattacttt gtttttcata tgagagatat
     4561 tgatcttgat aaccccaatg atcgttctcg ctgaataaat ttttgtcatt ttcaatactt
     4621 ttttttagag ttttgtttaa cgcagcttgt tcttttaaat ctttgatatc ttctttaaca
     4681 gcttttttct gcgcttggat ttcagtattg tctagagtta atagagtatc tccctttttc
     4741 accttatcaa cctgtttaat atcaactgtt tttactttgc cggctacttc gtttgttacg
     4801 ttgctgttag gcttggtata ttggatgtca gctgtcgttt ttagaatcac ttctttcttt
     4861 ccatagaaac taaaaacaat acatgcaata agtaaagcta tcagtatata tgtaaagaaa
     4921 acaccaattg gtttgggttt tgattcgtag aattctctgc tatccctcaa atcatttaaa
     4981 ttgaaaaagt tacgtttcat ctaaattgtc accatctctc tcgatggcat ttggttctcc
     5041 cacaactcat agtacttgcc ttttttcttc aataaatcat tgtggttccc atactctatg
     5101 atttctccat tttccatgac aaatattttg tcgcaattca taattgtact caaacgatga
     5161 gcaattataa tcgtagttac atcaacagtc tgatcgtata tcatctttga tattccctgt
     5221 tcggttgtcg tatcgagatt gctagttgat tcatccatta tgagaatgtt aggttttctt
     5281 aataatgctc tggcaattgc gagtctttgc ttctggcctc cagataaatt agacccgttt
     5341 tcttctacaa gagtatcgta tctcattggt aaatcattga taaaatcatg tactttagtt
     5401 tgtttacata cttctataat ctcttcaaag gtaaaactgc ctgagttccc aagcaaaagg
     5461 ttttcaagaa ttgatccttg tataaaatga gattcttgag gtatataact tatgctttcc
     5521 cttaacgcat tgatgtgaat atcatttata tgataaccat tgattgaaac ctcacctgat
     5581 tcagctgtat aaaatttcat taaaagctta gtcaaagtag attttcctga accgctttct
     5641 ccaacaaagg caactttctc tcctttttga atatgcagtg taatatcttt taagatgagc
     5701 cttcgagttc cgtatcgaaa attgattttt ttaaaagaaa gcggacctgt aattgacgac
     5761 gtcgatgtta ttcgcgcctc tttctctatt aattcgggtt ctagctttag aatttctccg
     5821 agccttttgg acgcaacaga agctgactga agcttagatt gtaggccgat gatgttttgt
     5881 aaaggattta agaagtaggt taataaggca ttatatgtaa taagctgacc gatagtaagg
     5941 gtgcctttca tgacctgagt tgatccgatc cacagtatca atgcaccgct tgctaaatcc
     6001 aaaaacattt ttatggaact ctgaaggtta tcaataactc cgtgtttaaa agctgatcgt
     6061 aagtatttca caaatctttt ttctgtttca aatgacatca tatattccgc attgtatgct
     6121 ttaacagttt cgatgccgtt aagcgtctca acaatctttg aagtcagctg cgcattgttt
     6181 tccatttctg tgttatttat attttcgtag ggttttataa aaatccaaac cgtcaaaata
     6241 taaaaaggta tgaaagccaa tgtgatgaga aataaagtag tattctgcag atataagaaa
     6301 ataccaacca taataagcat aatggtatcg agtatgaccg aaagcgatgc actgacaacc
     6361 gcatcgatca ctttattagc atcagtaaat ctggatataa tttcgccgac ttttctattg
     6421 ctgaaaaatt tcattggcaa agtaagcaca tgttgaaagt atccaaacat gatggagata
     6481 cttaattttt gacctaggag aatcattagg tattgcctaa aacctattaa gaaaacctta
     6541 aataaataca taatcaaaag gccgattgaa agaatatgta atgtgttact taatccatta
     6601 ggtaggattt gatcgatgat cgtctgaaag taaaaagtac cgaggatccc gaagacggta
     6661 ataataaagg atgctaaaaa cgtatgtata atcaacgatt tttgctgaag aatcaacctg
     6721 aaaatatcgg cacttatatt acttgtctcg gtctgttttt tataagtctc agtaggtgct
     6781 aaaagtatta agatgcctgt ccaaatctta aaaaaatcat ctttttgata tgtaacgagc
     6841 ccttttccag gatccgcaat gataatttta tctttactaa ttttatgtat aacaacgtaa
     6901 tgcaataatt gttgatctat aataatatgt gcaattgctg gaagagtaat ggactgatca
     6961 aaagctgtat gctctgcacg cacagctttt gctgaaaacc ccaactgttc ggcggctttt
     7021 accattccaa gagcactagt accttgtgta tcagttccag caatgtcacg tatataagct
     7081 agagagagct ttgagccata atgttttgca attgttgata ggcaggctgc tccacaatct
     7141 ttttgatcaa gttgtcgtac acaatgatat ctattaaaaa acatatacta ctctccataa
     7201 tgaaggtcat tttttagaat atatataata taaagaatag acatcatttt attacatttt
     7261 catggtttgt caaccttttt aaggtaaata tttattgtta tttagagctt ttggcacgtt
     7321 tatataatat aaatgcgtaa ttgatataga taagatataa agcaagatta aatacaccta
     7381 agtgaaaaaa ataagaaaga gatatacaaa ataaaccccc tgcgattata aagatataga
     7441 acaatttcat tttaccaact cctataattg ttaaaattca ttgtaagata taatagacaa
     7501 aatgtaaaat atatatggat gaatgcaata tatagtttgc atgggttttt tatatatgat
     7561 atgctacaga taaataaacc aatggagact tgccaatgaa taataatttg aagttggaaa
     7621 gaacaagagc gaatttaaca caggaacaac ttgccgaaaa aattggagtg acaagacaga
     7681 cgattggatt aattgaaaaa gggaagtata atccttcttt acaattatgt ttgaaaattt
     7741 gtatagaatt gaaagttact ctgaatgatg tattttggac gcataacagg gaggaagaaa
     7801 ctaatgaagg atgagagaat aagtcatatt gaaaataaaa taggtcatga aagctttctt
     7861 ttagtaattg ctttggtttt tgtctctttt atactttcga ttatgtttaa aatgccgagc
     7921 acgttaatga caattatcat attgtttgtt ggaagcggat attatggatt aagagctatg
     7981 ttaaaaggca ttttaagagt aaatctgaaa aagaagaaga agagttcgta ctttctttta
     8041 attgttttta cttttattct gtatatggca acgtcggtat tatttaaaat cattacattc
     8101 ccttttacaa ctaaagaatt cttattccaa attcttatgt atattttatg gctaattcct
     8161 tttagtctca tcatgtatac tacatataaa ttttcaaaca ggcagcagaa aaaagaatta
     8221 gagaattaat taagagagct taacctaaat aactgaatta ggttaagctc tcttttacta
     8281 tatataaatt gatcgatagg ttatagatga ttttatggaa aaaactattg atttaggatt
     8341 tattatgtaa tattataatt cccatggtaa atttatacta gttattatta tttacctgaa
     8401 taactttgag gaggaatatt gatgaacgca aaaagcataa aagacgttga acttcaggca
     8461 ttgactcttg aagaagctga acaaattgat ggaggaagtt atgctaaata tcttggcagt
     8521 gcagtagtta caggtgctgg cgcaggtgta gtcggaggag ttccaggtgt tattcttggt
     8581 gcccatgcag gtgcaattgc agggtcagtt ggttatttag gcgggtcatt aatcgcagga
     8641 aaatggcttt aaggagggaa tagcataaat ggaaaataat aatcgtcttt cagaattgaa
     8701 tgtaaaagaa atggaacaaa ttgatggcgg aggttggaga agtgcccttg gcggagcttt
     8761 ttcaggtgca ttagtcggtg cttcaacagt aggcgtcggt ggagcagctg ttggcggacc
     8821 cgttggtggt gccggcggag caattactgg cggcatagtt ggcggtatag ttggcggaat
     8881 aaacgcttgg taataaaaat acataaagaa ctagtttgaa cattatgtaa caagaccgga
     8941 aagagtatat cttttctcgg tcttgttata tttgtattta tatatacata atgttttgta
     9001 gcgtctattt attataaatt cttttaactg actatctcag ttattttgtt tcttccttcc
     9061 atttctcatc aatcagcatc ttgccaggcc atgtatacgc catgatgccg ccgtctgcgg
     9121 tgatgtcttc gcctgtgacg tatgagctgt cgtcagaagc gaggaaaagc gccaccgtcg
     9181 ccatttcctt cggcttgccg aggcggccga gcggtgtgat ccatttgttg gcttcgcgga
     9241 atttctcgcc catttcctgt tccttggtgc cagctaattt gtcaataagc ggcgtttcaa
     9301 tcgtacccgg tgagatggaa ttgacccgga tgccgtttct tgcgtaatca attgccatcg
     9361 ctcttgtcag gtttgtgatt ccgccttttg cggcgttata gccggagcgg tcaaggtccg
     9421 cagccctgcc tgacatggag gaggtgttga tgatggagcc tcccttttcg agcataagcg
     9481 gaatcagata tttgctgcaa agaaacgtgc cgcgcagatc gactgcgatt atgcggtcaa
     9541 acagatctac gggatattcg tgcacttttc cgccttcttg atcgacgccg gcgttgttaa
     9601 agagaatatc aatcgttccg tacgcgtctt tgagttgatc agcaaattgc tttacgtttt
     9661 cttcatctga cacatcaagg tgaaaagcct cagcctgtcc tccgttttgt ctgatcgctt
     9721 cgactgtctc tttcatttga tcttcattca tatcgccgaa aatcacacgc gcgccttcat
     9781 tggcaaaaac ctctgccgtt gcttgtccaa tgcctgtcgc agcgcctgtg atcacagcgg
     9841 ttttgttatc aagtcttccc ataacatgaa tcctcctttt tctagttgtc ttcccgctgt
     9901 gtgcagtgat aaacatgtga gaaaagaaat gcctgcatat gttaaaatga actggaaatt
     9961 gttgggaggt tttatgtgtt ttgaagatac agcataagaa ggaacttaaa ttttattgtc
    10021 tcattacgat tccggctgcg tttgctgtgc tgactgtcat ctctttttta ttgcaagaga
    10081 ttacgtttcc ggttacagct agcgcatttc tgaatgcttc atggcataat ctattgtttc
    10141 tgataccgtt ctgtttgttt ttctatccgg tgcatatttg gatgaagcgg gagtttagcc
    10201 gatggaatga tgcaggacaa aagagaggtt gatcctctct ttttcttatc agactgtcta
    10261 gaaaaaatag tgaaaacacc cccaactaat gttaaattta catatatacg catctattga
    10321 tctttgatga aaatcgtatt gacatgagtc gtcatttatg ataaatagat gctgaaaaga
    10381 gtttacataa catcacaaag catgaaaaag gagcgagctg aatggctaaa aaagagttta
    10441 aagcagagtc caaacgactg ctggatatga tgattaactc catttacact caaaaagaaa
    10501 tctttcttcg cgagttaatt tccaatgcga gtgacgcgat tgacaaaatc tattacaaag
    10561 cgctgacaga tgatgcgcta accttcgata aagacaatta ctacataaaa gtcgcggctg
    10621 acaaaggcgc gagaacactg accatcacgg atacagggat tggaatgaca aaggacgagc
    10681 ttgaacagca cctcggtacg attgcgaaaa gcggctctct tgcgtttaaa aaagaaaacg
    10741 aactgaagga cggccatgac atcatcgggc aattcggtgt cggattttat gcggcgttta
    10801 tggttgccga tgtggtgacc gttatcagta aggcgctcgg cagcgaagaa gcgtataaat
    10861 gggaatctgc tggcgcagac ggctatacaa ttgagccgtg tgaaaaggat tctgtcggca
    10921 cagacattat cctgaagatc aaagagaaca cggaagatga gagctatgat gagtttttag
    10981 aagaatatcg tttaaaagcg atcatcaaaa agtactctga cttcattcgc tacccgatca
    11041 aaatggatac aacggttaat aagccgaagg aaggcagcga caatgaattt gaagaggtgc
    11101 aggaggaaca gacggttaac agcatggtgc cgatctggag aaaaaacaag agcgagctga
    11161 cagatgagga ctatgaaacg ttctacgctg aaaagcatta cggatttgat aaaccgctca
    11221 ctcatgtcca tatcagtgtt gacggtgccg tgcgctacaa cgccatttta tttattcctg
    11281 aaaacatgcc gtttgactat tattctaagg aatatgagaa aggcttggag ctctattcca
    11341 acggcgtgct catcatgaac aaatgcgcgg atctgcttcc ggaccacttc agttttgtga
    11401 agggtatggt cgattctgag gacctgtcgc tgaacatttc cagagaaatg ctgcagcatg
    11461 accgccagct gaagctgatt gcgaaaaaca tcagcaaaaa gatcaaaagc gagctgcaga
    11521 gcctgctgaa aaaagacaga gaaaaatatg agaccttcta caaatcgttc ggcagacagc
    11581 tgaagttcgg cgtgtacaat gattttggcg cgaataaaga tcaattgaag gatcttttat
    11641 tattctactc ttccaaagag aaaaaactgg tcagcctgga cgagtacgta tccagaatgc
    11701 ctgaagagca gaaatatatc tactacgcga ccggtgattc atacgatcgc attgaaaaac
    11761 tgccgcaaac ggaaatggta gcggacaaag gctatgaaat tctttacttt acagaggaca
    11821 tcgatgaatt tgcgatcaaa atgctcgctt catatcaaga aaaagagttc aaatctgtat
    11881 caagcggcga tcttggcatc gattcagaag aggatcaaaa gcagtctgaa gaagaggaaa
    11941 gcaagtacaa ggatctgttt gaggaaatga aaaatattct gtctgacaaa gtgaaaaacg
    12001 tcagagtatc caaacgcctc aaatctcatc cggtctgcct tgcagctgac ggtgaagtga
    12061 caatcgagat ggaaaaaatc ttaaacgcga tgccggacag ccaaaatgta aaagcggaca
    12121 aagtgctgga aatcaacccg aatcacgagg tattcaagac gctgcagaac gctttcgaac
    12181 aaga
//
