LOCUS       NZ_CP045704            30834 bp    DNA     linear   CON 03-SEP-2024
DEFINITION  Streptomyces rutgersensis strain NBH77 chromosome, complete genome.
ACCESSION   NZ_CP045704
VERSION     NZ_CP045704.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces rutgersensis
  ORGANISM  Streptomyces rutgersensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces diastaticus group.
REFERENCE   1  (bases 1 to 6848830)
  AUTHORS   Benaud,N., Edwards,R.J., Amos,T.G., D'Agostino,P.M.,
            Gutierrez-Chavez,C., Montgomery,K., Nicetic,I. and Ferrari,B.C.
  TITLE     Antarctic desert soil bacteria exhibit high novel natural product
            potential, evaluated through long-read genome sequencing and
            comparative genomics
  JOURNAL   Environ Microbiol 23 (7), 3646-3664 (2021)
   PUBMED   33140504
REFERENCE   2  (bases 1 to 6848830)
  AUTHORS   Benaud,N., Edwards,R.J. and Ferrari,B.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-OCT-2019) School of Biotechnology and Biomolecular
            Sciences, University of New South Wales, Botany St, Sydney, NSW
            2052, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 07-DEC-2018
            Assembly Method                   :: FALCON v. v 1.8.6
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 62.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014216335.1-RS_2024_09_03
            Annotation Date                   :: 09/03/2024 04:34:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,921
            CDSs (total)                      :: 5,831
            Genes (coding)                    :: 5,642
            CDSs (with protein)               :: 5,642
            Genes (RNA)                       :: 90
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 189
            CDSs (without protein)            :: 189
            Pseudo Genes (ambiguous residues) :: 0 of 189
            Pseudo Genes (frameshifted)       :: 102 of 189
            Pseudo Genes (incomplete)         :: 130 of 189
            Pseudo Genes (internal stop)      :: 14 of 189
            Pseudo Genes (multiple problems)  :: 50 of 189
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:08:04
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6638402
            Orig. end                         :: 6669236
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP045704.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Belinda Ferrari, QAP Lab
            4002, Bioscience South E26, UNSW Sydney, Australia 2052 (Quarantine
            regulated isolate).
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..30834
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /product="lanthipeptide-class-iii"
                     /region_number="22"
                     /rules="cds(LANC_like and DUF4135)"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..30834
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="neighbouring"
                     /product="lanthipeptide-class-ii"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..23024
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23024
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13024](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13024
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    726..744
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 16.4"
                     /tool="antismash"
     CDS             1588..1692
                     /gene="allorf_6639990_6640094"
                     /locus_tag="allorf_6639990_6640094"
                     /protein_id="allorf_6639990_6640094"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MDLIRHVTDADPGLRAGTGSDGPARCHGARCPSP"
     CDS_motif       1588..1674
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MDLIRHVTDADPGLRAGTGSDGPARCHGA"
                     /locus_tag="allorf_6639990_6640094_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       1675..1692
                     /prepeptide="core"
                     /locus_tag="allorf_6639990_6640094_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.20"
                     /molecular_weight="540.6"
                     /monoisotopic_mass="540.3"
                     /core_sequence="RCPSP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MDLIRHVTDADPGLRAGTGSDGPARCHGA"
                     /leader_location="[1587:1674](+)"
     gene            complement(1818..2330)
                     /locus_tag="F0345_RS27640"
                     /old_locus_tag="F0345_27685"
     CDS             complement(1818..2330)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F0345_RS27640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F0345_27685"
                     /product="hypothetical protein"
                     /protein_id="WP_185393651.1"
                     /transl_table=11
                     /translation="MLSGPPPGPEMKLPADLKVTFEETKLKDPDQAAALRDARLYAKST
                     VFGIAEQDPESEAYGYYAVPGSQAEKYAKARIGVYVDGGLTIAGERQHSRAEVRPGKKD
                     GYVVTFCSDESKVKGKHEASGETFTGDPGPTNLWHWTLDMVPSPKIDGLWLTQEAIMKG
                     RASAECG"
     gene            2626..3483
                     /locus_tag="F0345_RS27645"
                     /old_locus_tag="F0345_27690"
     CDS             2626..3483
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972626.1"
                     /locus_tag="F0345_RS27645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_27690"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_100454221.1"
                     /transl_table=11
                     /translation="MKSDEGPTSAPTADAAVRVRAVIANAGVSQREFARRVVMDPSKLS
                     RALSGTRRFTVAELARIADEGRVDADWLLGSRPREKGTAPAVGIEGGRPLQIVRETVRL
                     VAERGFHAVRVADIARACATSSAAIHYHFPGRAELLEAAVRWCMDEDTARRAAHLAEAD
                     DAAAELRQLIALQTPRTAQQRRQWAVWLDLWAEAARSTAVGRLHSEYYRQWRETVTDVL
                     RRGVGQGVFRAGIDPDAAALTLTALIDGLATHVLSASGPSSATAADAMHATLTAHVTHT
                     ILAP"
     gene            3555..4448
                     /locus_tag="F0345_RS27650"
                     /old_locus_tag="F0345_27695"
     CDS             3555..4448
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003946448.1"
                     /locus_tag="F0345_RS27650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_27695"
                     /product="3-keto-5-aminohexanoate cleavage protein"
                     /protein_id="WP_100454223.1"
                     /transl_table=11
                     /translation="MPMTENVIITCALTGAGDTVRKSPHVPVTPEQIARNAVEAAAAGA
                     AVVHIHVRDPETGGPSRDPKLYREVVERIKETGTDIVINLTAGMGGDLVIDPDDPLTHL
                     PGTDLVGGLERLPHVEDLLPDICTLDCGSLNFGDGSNLYVSTPDMLRAGARRIQELGVR
                     PELEIFDTGQLWFAKQLLAEGLLDDPTVFQLCMGVPWGAPADPGVLQSMVNMLPDGARW
                     ASFALGRMQMPWVAQSILLGGHVRVGLEDNLYLGKGNKATNAQLVERAVTLTESIGARV
                     ATPDEARATLGLKTRK"
     gene            4476..5492
                     /locus_tag="F0345_RS27655"
                     /old_locus_tag="F0345_27700"
     CDS             4476..5492
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /GO_process="GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1095: 3-hydroxybutyryl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414044.1"
                     /locus_tag="F0345_RS27655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_27700"
                     /product="3-hydroxyacyl-CoA dehydrogenase NAD-binding
                     domain-containing protein"
                     /protein_id="WP_185393652.1"
                     /transl_table=11
                     /translation="MTSPEKTSPDPTSPKTTSSGITPPENVRRVACVGAGVIGGGWVAH
                     FLARGYDVTAWDPAPGAAQKLRRLVDAAWPALTSLGLAEGASADRLTVAATLEQAVADA
                     EFVQESAPEKLDLKRDLLARLDAATPPGVVIASSTSGYPMTDMQTTAADPSRLVVGHPF
                     NPPYLIPLVEVVGGERTDAAAVAWAARFYESAGKSVITMDNEVPGFIANRLQEALWREA
                     LHMVANGEATVRDIDLSITEGPGLRWAVMGPMLTFALAGGEGGMAHMLDHFGPSLKSPW
                     TRLEAPELDTELYDAVVTGCDEAAGGRTIADLVAERDQGVIEVLRATGRLGREGGAR"
     gene            5489..5968
                     /locus_tag="F0345_RS27660"
                     /old_locus_tag="F0345_27705"
     CDS             5489..5968
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 4HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414045.1"
                     /locus_tag="F0345_RS27660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_27705"
                     /product="thioesterase family protein"
                     /protein_id="WP_185393653.1"
                     /sec_met_domain="4HBT_2 (E-value: 3.3e-26, bitscore: 90.5,
                     seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRLPLFHSTVRPEWIDYNGHMSEAFYVLVFGHATDALMDETGLG
                     SGYRESTGCSLYTVESHIRFLQDVSDTAHLAVRTRVLGAAVRKAHFAHEMYLVSDPASE
                     PASAAAPVATTELLAVHVDQRAGRAAAFPDAVRRRFTELTEPAPVWAGRSIAAVA"
     CDS             complement(6146..6301)
                     /gene="allorf_6644548_6644703"
                     /locus_tag="allorf_6644548_6644703"
                     /protein_id="allorf_6644548_6644703"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MTELGEGEPGSGVGAMTATGPRPCGQDSVRCGFGLCRAADGVVDD
                     HGQGGE"
     CDS_motif       complement(6257..6301)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTELGEGEPGSGVGA"
                     /locus_tag="allorf_6644548_6644703_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(6146..6256)
                     /prepeptide="core"
                     /locus_tag="allorf_6644548_6644703_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.50"
                     /molecular_weight="3566.9"
                     /monoisotopic_mass="3564.6"
                     /core_sequence="MTATGPRPCGQDSVRCGFGLCRAADGVVDDHGQGGE"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTELGEGEPGSGVGA"
                     /leader_location="[6256:6301](-)"
     gene            6738..7655
                     /locus_tag="F0345_RS27665"
                     /old_locus_tag="F0345_27710"
     CDS             6738..7655
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F0345_RS27665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F0345_27710"
                     /product="hypothetical protein"
                     /protein_id="WP_100454227.1"
                     /transl_table=11
                     /translation="MINPDAPEADKQLLRTARRNPAALDLSGSGAPTHTKRIVVAVVST
                     TALGAYFVTHRFGSSDRPIPGVLLARIHDALSTAETVIGWGALVAGMATAAYGVLLVTG
                     RARRRRLTERYWAAVRDHVVDPEELTDECRGLLARGQQATTTVMRSRVHRHGLIDKAHN
                     EAALPRQEWELATTLRDYSRLAGAEPGKPAGVEVVTLLQRRRDALRASLDGVERRVVAL
                     EKYADQVVEADRRYEEWKQIEELSEDADAVLDLLARTARDDMAVAEIEGLTGQAAAVAE
                     SLTTALESARKAAFVALPPPAATA"
     gene            complement(7754..8980)
                     /locus_tag="F0345_RS27670"
                     /old_locus_tag="F0345_27715"
     CDS             complement(7754..8980)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018554039.1"
                     /locus_tag="F0345_RS27670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_27715"
                     /product="hydroxymethylglutaryl-CoA reductase"
                     /protein_id="WP_229842156.1"
                     /transl_table=11
                     /translation="MNSLQHTRLDAGKLTGNIEGLVGAVEIPIGVAGPLLFCGTNVRGE
                     RYAPLATTEGALVSSATRGALAVTMAGGVSTHAVSQAMTRAPVFAFSRLADASRFAATV
                     PQHIGDLRTAVRQVSSHAVLVSIEPVILGRAVHLRFRYTTGDAAGQNMTTVCTWHACQW
                     ILRQSHLVTDDALEFFLVEGNSSGDKKASALAMAEGRGIRVAADCVLPTGVIERVLRTT
                     PDELVRGYQHIAAGAVHSAMLGSNANSANVVAAIFTATGQDIACVHESGMGHFVLERTR
                     DGVHASMTLPGLALGTVGGGTHLPTQHEMLALMGCTGPGSAVRLAEIIAGFALALDLST
                     VSAAVSDDFASAHERLGRNRLPHQSDTGRHVTPSAGAEGPVTEATGPLSPPPDVHTQER
                     EASAEGGAR"
     cand_cluster    8243..30834
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    8243..30834
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[18242:20834](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(18243..20834)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="2"
     CDS             complement(9162..9347)
                     /gene="allorf_6647564_6647749"
                     /locus_tag="allorf_6647564_6647749"
                     /protein_id="allorf_6647564_6647749"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGSRVVELAPGLPPGTGVGSSVSASEAKSLPGTSRRRSGDRVPPQ
                     TRCGRGHSSPRLRPAV"
     CDS_motif       complement(9249..9347)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MGSRVVELAPGLPPGTGVGSSVSASEAKSLPGT"
                     /locus_tag="allorf_6647564_6647749_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9162..9248)
                     /prepeptide="core"
                     /locus_tag="allorf_6647564_6647749_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.20"
                     /molecular_weight="3052.4"
                     /monoisotopic_mass="3050.7"
                     /core_sequence="SRRRSGDRVPPQTRCGRGHSSPRLRPAV"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGSRVVELAPGLPPGTGVGSSVSASEAKSLPGT"
                     /leader_location="[9248:9347](-)"
                     /alternative_weights="3070.4"
                     /alternative_weights="3088.5"
                     /alternative_weights="3106.5"
                     /alternative_weights="3124.5"
     misc_feature    9241..9255
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.37"
                     /tool="antismash"
     gene            10001..13024
                     /locus_tag="F0345_RS27675"
                     /old_locus_tag="F0345_27720"
     CDS             10001..13024
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015508337.1"
                     /locus_tag="F0345_RS27675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_27720"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_185393654.1"
                     /sec_met_domain="DUF4135 (E-value: 8.5e-104, bitscore:
                     346.1, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.3e-28, bitscore:
                     97.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERNASGPGCGAARPGPGPDPAGRGAVALLENGEQRTASGAWWAP
                     ALRTEERAGGIPDWAEWVEQVLAATPAALPLPEEEYEGLSGFERVLAPFAEAAGDRMAA
                     ALGGEERGLVDLAAVRAGLVRAVGPRLARIAARVLVTELHRAREAGGLTGGDSRARFRE
                     FLRRAGGRRGLAALLRAHPVLARLLGRVSLDAADAFAELLRRLVADHVALAEAGLPCGS
                     DDRLLVDVEAGAGDSHGGGRTVALLRFADGTRLVYKPRPVAAHRHFNDLADWLGRLPGA
                     PRLRTLTVLDRGTHGWVEFVEVLPCRTEPQVREFYRRQGALLALLHALDGTDLHHENLI
                     AHGEHPVLVDVETLFHPALPIAASDDPASRALHDSVHRVGLLPQFLLGDDSALDMSAVG
                     GGRAALSPVALAGWADCGTDTMRLVRRPGRFRESANRPRLHERTAEPAAYTAELCEGFR
                     AAYTALGEARAELLGPTGLLERFRRDEVRVVARPTAVYATLLDETTHPELMREAGARDA
                     VLARLREGTLGHPALPGLEDEEIAQLWSHDVPVFAVRAGGTALTGVTGRAVPGTVPISG
                     LARATGKIAALDSVDRQDQEWVIRAAMVSASTTPAHHPAGPGRGPRPAFAPEPERLLAA
                     ARSLGDQLVSLAYRAADRANWLGLELLGDRYWRLGPMPADLAAGYCGPALFLAQLADVT
                     GVARYAETASASLAPVAGLLDALHEDPTAPPAVGSGAFAGLGGLTYTLLEVERLLGEPA
                     CAESLPAALRLLEAAAAGERETGVGAGTAGGLAVLLAAHRATGRPETLRAAGRCAERLA
                     AAGPPAGPGFLDGSAGTGWALLRYAERSGAPRFREAGLEALREAVAALPAANGAADEGW
                     CHGRAGIALALADSPAALADHRLAAWLTATARLLRGAGPRPDDSLCHGEAGLLELLGHG
                     ALAGARAGLVHRTGALLASVEDGGPGCGTPDHVPHAGLLTGLAGIGHGLLRAGFPDRVP
                     SVLLLDLPTLTAAPDHHP"
     gene            13103..13294
                     /locus_tag="F0345_RS27680"
                     /old_locus_tag="F0345_27725"
     CDS             13103..13294
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003946487.1"
                     /locus_tag="F0345_RS27680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_27725"
                     /product="hypothetical protein"
                     /protein_id="WP_100454233.1"
                     /transl_table=11
                     /translation="MQIDDAATHLTGGTGESAGEHPVGAITLFTTGALGLRSRLLSASE
                     GGAAYSHELPWTTMTAPQ"
     misc_feature    complement(13353..13368)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.65"
                     /tool="antismash"
     gene            13359..16280
                     /locus_tag="F0345_RS27685"
                     /old_locus_tag="F0345_27730"
     CDS             13359..16280
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015508338.1"
                     /locus_tag="F0345_RS27685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_27730"
                     /product="AAA family ATPase"
                     /protein_id="WP_124287746.1"
                     /transl_table=11
                     /translation="MRATSSVIVGRDSESALLAKGLAAAGRSSGGAVFLVGEAGIGKSR
                     LAGQCAFDAYAREVPVLRGRATSTGLVVPYRPLMEALSSRFRAAGTPEEPELEPFRPAL
                     SALVPEWRRHGPEFPASVVELAEALLRLLSVLGRERGCVMVLEDLHDSDTETIAVVEYV
                     ADNLADLPVLLLGTLRPEPGPALDVTRAAAGRQTATVLELGPLDDTQVHRMAEACLNAA
                     PGEVPAEAHRRIARRAGGNPYLVEVLLADLVDSGTLHRTDGGWRCEDGPDGGVPTGVVR
                     SWAARLDRLDPPVRELLLTSATLGSTFQVPLLQTVLGYEERALFAHLRAATEAGIIAPD
                     GAAPDRYAFRHALTAEALTAALLPAERAATARRAADALEELGPAMSEDARQLLATLRLA
                     AGDAAAAGAHLAEAGRRMLGQGAAGSAAVLLERAHGLTPDARRPEVAASLAVALAEAGR
                     LAEAFTLAAGLPPVPPGTPAAAERADAHIRVAWAAVMGEHPEEAGRRVRAARALLGPAP
                     PPAQQAALAVVEGHLVLLPGGAGEEGTADAAEAARRAAAVAEEHGLPVVACQAWQLLGL
                     LSRDQGFDEADACLERMLAVSERHQLAAWRMEALVRLGANAFLRTGDATRLAAARTAAG
                     ELGALALTQTVDGLIAMNAVLCGDWEKARATVDRSVDAAARVRNLSAHRYLLLADATLA
                     AHQGRRRERDAALLRFRRAGGEDSLLVPLQRGLCLAVGALLDEDRPGALDHLEAAVAWE
                     RERPSLYFLGGRWGLLPLLRALDGTGDTADHRAALASHGAQLAWNKLFLGMADAVHRGR
                     GGDAAGAAEAVRSALRTGEAFPLARHLALRLVAEAAVADGWGEPVTWLRTAEEFFHAAA
                     VQPVASACRAALRRAGASAPQRRDGRDRIPAPLRTSGVTPREYEVFVLLADRPGNQQIA
                     RHLSISPRTVEKHMASLLAKTGRQDRTALCEFAAECASAAVRR"
     gene            16435..18237
                     /locus_tag="F0345_RS27690"
                     /old_locus_tag="F0345_27735"
     CDS             16435..18237
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010639230.1"
                     /locus_tag="F0345_RS27690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_27735"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_100454237.1"
                     /transl_table=11
                     /translation="MTPAPRTSAHPSRPHFTVLGPLAAHRDGVPLSLGPLKQRLVLGLL
                     LSRPNTPVGTDALTDAVWPDDPPRTARKNLQVYVSSLRTLLGDGRTASPGLLVHDCGGY
                     VLRVEDDEVDALRMRRLARSAAGLEPASAVGLLREAVGLWQSTPLHDLRRSPALAAEGE
                     RLERRCLSVHEEWAECELALGRGPAVVEELRELAERHPLRERLHAAWMTALHQSGRRSE
                     ALAVYDEYRQELARELGLEPGGAMADRYRDVLTESRSHGIARSAAPAELPPDPPVFTGR
                     GGQLRELIDALDRPGGEGGTVLLTGPAGSGKTALAVRAARLLADRYPDGRLLVRLRDSA
                     GAAQPATTVLDRLAGLTGVPATPQAWRRWLVRHRALVVLDDAPGEHTVRGLLPTDGRSA
                     VLVTARGLLGGLAPVGRVDVPPMDPAEALDLLARFVGTARVAADRAAALRVVHGCGLLP
                     LGVRVAGMRLSVLRHLPLAEYADRLADPACALDELSAGDVLVRDRLAVAWRDLPAAQAQ
                     ALAGLASAGLEGPFTLAEAAAALDSPVRAALRTVEALIGSGAVTTSGGEVTAHAAHYEV
                     PRLTWLLARENAEERIGRPVVVPG"
     gene            complement(18243..20834)
                     /gene="lanKC"
                     /locus_tag="F0345_RS27695"
                     /old_locus_tag="F0345_27740"
     CDS             complement(18243..20834)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018895798.1"
                     /locus_tag="F0345_RS27695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_27740"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_185393655.1"
                     /sec_met_domain="micKC (E-value: 9.1e-213, bitscore: 707.1,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 1.2e-08, bitscore: 33.0,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGLHQNQLYSLADPTYYETPARLPDEGTRFALDQQAAPPGWGKG
                     RSGLWTSLRPDGAPLTEQGWKVHVSTVPEEAASTLRETVRICLRHGVPVKFLRSRQALA
                     LMSDKYMARGSSGKFVTAYPPDEPAFLRLVAELSAALDGRRGPYILSDLRIGDAPVYVR
                     YGSFTDRWCRAADGSTVPALRAPDGRLVPDERDVVFRVPPWVTVPPELGPHLAARAAAR
                     DDGFPYVVERALQFSNAGGIYLARHRRSGERVVLREARPHCGLDSAGDDAVTRLHREHR
                     ALRRLDGLECVPRVHGVRTVWEHHFLVEEHVEGRTLFEEIVARYALVRGERSDAELAAY
                     RAWVDEVTDRLASALAAVHARGLRFGDLHPANIVLRPDGRLVLIDFEYATELEDPSPFA
                     GAFGMQAPAGTAGPEADAYALWSTWLHMLMPLTEMAGHDRRKALVLERWARDRYRLGPD
                     AGPPRPAPLTSAMDRTDPVERLLTGPEPDWDRLRAMLVAGVRAAATPERLDRLFPGGPD
                     GFASGGVCAAHGAAGVLHALRHVGAEVPGEWVRWLADASLRRPPERAGGLLDGLPGAAA
                     VLAASGEGDAAAELLERASAAPPPTGADLATGRAGRALAALRVTRAAGGPGACPPPEVF
                     RTASDLARLARGETVPGLTAPPSAGLLRGLSGAALLHLELYELTGERHLLDAARDVLHR
                     EAGHCVRMPGGSVQVKDGRRHLLYLDQGSGGFALVARAYLEHREDALLSALLPGVRQGC
                     VLEFVREPGLFTGRAGLTATAHALDAASGDGSARTAPAPDVLASVRNLTWHLVQDGDHL
                     LVPGAGLRRFSTDLATGSAGLLLALHTLAARHGAPGAPTGPRALLSLLTLG"
     gene            complement(20874..22208)
                     /locus_tag="F0345_RS27700"
                     /old_locus_tag="F0345_27745"
     CDS             complement(20874..22208)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010639225.1"
                     /locus_tag="F0345_RS27700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_27745"
                     /product="MFS transporter"
                     /protein_id="WP_185393656.1"
                     /transl_table=11
                     /translation="MTEPERAVALRANRDFRLLWLSGLFAVIGTQMTALALPLLVLRET
                     GSAVQAGAIGTVSVASLLVTMLPGGVVADRVERRRLMRLCDLGSLTVVTALVVAVWNGH
                     APLALVLLVAAAGAVITSLYGPAAFGLMRAVVPKDQMGAATARLQARTATARLVGPLIG
                     GALFGVHPVLPFLAEAVGLALSTLCVALVRTRSRPAARPGRAFSRRELTAGLAFLWRLP
                     YLRTVLLVFGLGMNFGFGAMSFTALSVFSDSGRSGVGGGLVVACTSAGALAGALLAPRL
                     RPERRTALLVPATCWLCVATAGALAVVRVPLVAGVLVMACMFLSTVASIGFLSTLLVVT
                     PDDRVGRVQSSAGFLSSLVQPFGPLAGGALLGALGPAGAFTAIGTVLAVSAAVVTFAPS
                     ARAVPPHEGTAEDEGTPGKPAPPPAAGGDGPGTGRTDPAAAAPPH"
     gene            complement(22384..22551)
                     /locus_tag="F0345_RS27705"
     CDS             complement(22384..22551)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008415324.1"
                     /locus_tag="F0345_RS27705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_162911630.1"
                     /transl_table=11
                     /translation="MSEKTNPETPETVESPEVEAHSASVLDLQGTTSVDQEHIADGNCI
                     SVLSVVENQK"
     gene            22971..24068
                     /locus_tag="F0345_RS27710"
                     /old_locus_tag="F0345_27750"
     CDS             22971..24068
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003946478.1"
                     /locus_tag="F0345_RS27710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_27750"
                     /product="radical SAM protein"
                     /protein_id="WP_185393657.1"
                     /transl_table=11
                     /translation="MRLAEIIGLRPEPAAGVLVTLTRRCPLSCAHCSTASGPDADERPD
                     PGDLRRFVASFTARDRPEVMMLTGGEPLLMPGLVRELAASAKERGTRTAVLSGMFFARA
                     RSVPRAVLRAAAAVDHFSASLDLHHEREVPRTAVFAALRALSATGTRVSLHLTGTGPDD
                     PYLADATAAVEREFGGTLPVLVNEIRAFGRAATWARPARPVGGDDGAAPAPCAMAAWPV
                     VAFDGTVLACCNQHTVDRRPVPPHLRLGHIAEDSWATVRARALDSPLLRTVRTVGPLHL
                     RARHAPDAPRAASYCDACRQLSALPGAVAAAERTAAGATGALLDLTVGRSRRAHGPTAL
                     VRAHGCAAYAAWVERPGPGEPGTVR"
     gene            24065..24799
                     /locus_tag="F0345_RS27715"
                     /old_locus_tag="F0345_27755"
     CDS             24065..24799
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010639219.1"
                     /locus_tag="F0345_RS27715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_27755"
                     /product="iron-containing redox enzyme family protein"
                     /protein_id="WP_100454245.1"
                     /transl_table=11
                     /translation="MSGGSASGRLRAKLSLVEAGPHGATAALWQADRPRDRYLAYLVTM
                     HQVIRASVPLMERAADLADRAARCGADPLAAPLARYLRAHVLEETGHDAWLLEDLAAAG
                     VDTKAVLRAVPPPDVAALTGAQHYWTEHHHPLALIGYIAVLEGHAPAARLGAVLARRTC
                     LPEAAFRTVRAHAHLDADHVDDVYALLDSLPLTGRDEALLAVSALHTVDALTRIFVRLG
                     RRAPAAVPLRETGRPTPTGGPG"
     gene            24796..25002
                     /locus_tag="F0345_RS27720"
                     /old_locus_tag="F0345_27760"
     CDS             24796..25002
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010639217.1"
                     /locus_tag="F0345_RS27720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_27760"
                     /product="aroma-sacti cluster domain-containing protein"
                     /protein_id="WP_100454247.1"
                     /transl_table=11
                     /translation="MTPPQRPDLLTRLHEAGFAVDLLTEEQREVLTGLEPEELAVLLDI
                     KERLDAVGPEVQAHGEIAGGALF"
     gene            25095..28241
                     /locus_tag="F0345_RS27725"
                     /old_locus_tag="F0345_27765"
     CDS             25095..28241
                     /GO_process="GO:0009190 - cyclic nucleotide biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0035556 - intracellular signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015508342.1"
                     /locus_tag="F0345_RS27725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_27765"
                     /product="adenylate/guanylate cyclase domain-containing
                     protein"
                     /protein_id="WP_185393658.1"
                     /transl_table=11
                     /translation="MTCSACHQGLPADARFCPACGTPAAPGAGRPVPAAPGLPLPEDKR
                     KPVTVLFCDMVGSTALSGALDPETLRTLTLRWFGLMSAEIEARGGTPEKFIGDAVMAVF
                     GVPHVHEDDARRALAAALGIREALKRFNAELERTLGLRIGIRIGVNTGQVVAGSDATAR
                     QALVSGETVNVAARLEQNAGPGEILIGPQTLSAAGPTVAVEEAGPLALKGKTDRVPAYR
                     LLALGADDPELLRRFDIAFVGRRTELARLAEEAHAARRGTRLLHLAGEAGTGKTRLLRE
                     WRTRATGPGHLVHGAGRCRGYGDHGSLAPLADAVRTVLAEAPRSADGHQDDIALGVLAA
                     GLLDDGTPNVPLEEMCAALATVLARTARTCRPVLVLDDWHWAPPPLVRAVELLHIRLGD
                     APVLLVCAGRPGGAAPPATAIPLRLEGLDRAEAARLAADLIGAPRTPVAARLLERAEGN
                     PLYLEQLLLPADAGTPALPDDELPPTLQALLGARIGALDPAERFVLDIACVVGREFDPA
                     ELARLAATAPGTAAPPDGDEPPTVLPVLQRLRRRRLVEPVGTGPRSPYRFAGGLVQEVA
                     YASLSKRTKAERHEQAARLPSVTQAGDAAVGGHLERACRLRTALGLVDDRTARLRARAA
                     TALGRAGAQAVARSDLTWADSLLGRSVELAEPDAPGAVTALRRLGEVRVALGRTEEGTA
                     LLRRVAADGAVPVEAAHARLALAVQDPGAALASVARAVLPVFEAAGDRIGQARARLRLG
                     QQRQATGRHEEADRELVRVLDQAVAAGAEPERAAALGAVGVSLWRGPEPVAAAIHRCRA
                     LLAAHGDGRPTVGVTLNCPLAVLLALDDRPGEAHAALAEAARLAAELAYAEAGVFLPVF
                     RATVTTLAGRRVEALRLLADADAEAERLGAGGMRVAIALETGRLLLDEGRVHEAAERLT
                     PAVRADALSRADTVDLSGLRARLAAAYGRGERALAAADEAVATAALTDSLPLRATAALD
                     RARVLASLGAHEGAEAEARRAEEHFSDKGHLPGARAARALLGGPDGGVQAGTTTTEKAS
                     "
     gene            28245..29123
                     /locus_tag="F0345_RS27730"
                     /old_locus_tag="F0345_27770"
     CDS             28245..29123
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003946474.1"
                     /locus_tag="F0345_RS27730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_27770"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_100454252.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 6.7e-23, bitscore:
                     79.8, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTTTTGAPPGTALTWSLRGRGPDDLPVVADPAAPDGPAEGTGRG
                     VRVCVVDSGVERDHPLVGPLAGSWVVVKDGATGEAEVLPTTTGDTCGHGTACAGIIRRT
                     APECEITSVRVLGERFSGTGDVLLAGLRWAVDQGFDLINLSLSTTRTRFAHQLHELADR
                     AYFARTVLVASAHNTPVESFPWRFASVLSVGSHQEDDPALHLYNPSPPVEFFAPGQNVT
                     VPWLGGATIRTTGNSFATPYITGLSARLLSARPRMTPFQLKSALYLSAANVTLGPRHHL
                     PAGEASDDSEN"
     gene            29107..29694
                     /locus_tag="F0345_RS27735"
                     /old_locus_tag="F0345_27775"
     CDS             29107..29694
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008411682.1"
                     /locus_tag="F0345_RS27735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F0345_27775"
                     /product="GAF domain-containing protein"
                     /protein_id="WP_100454255.1"
                     /transl_table=11
                     /translation="MTPRTDPVTAPVPLPGAAGDARRRELLQSVVEVARAIFGAAAGSV
                     LLLDEERDELVFAAVSGEGEEFLVGNRFPAGSGIAGWVATSGEPVVVDDLTANRSFDRS
                     VAESTEYVPDALMAAPLVSDGRVLGVLEVLDPSPQARSGLPELDLLALFARQAATALRV
                     VSPDPPADLPPSRRADALRLLGSLEQLLREPA"
     CDS             29899..29982
                     /gene="allorf_6668301_6668384"
                     /locus_tag="allorf_6668301_6668384"
                     /protein_id="allorf_6668301_6668384"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MAGTVGGAATSEPTAGRAVAEPSRCAG"
     CDS_motif       29899..29922
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MAGTVGGA"
                     /locus_tag="allorf_6668301_6668384_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       29923..29982
                     /prepeptide="core"
                     /locus_tag="allorf_6668301_6668384_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.70"
                     /molecular_weight="1758.9"
                     /monoisotopic_mass="1757.9"
                     /core_sequence="ATSEPTAGRAVAEPSRCAG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAGTVGGA"
                     /leader_location="[29898:29922](+)"
                     /alternative_weights="1776.9"
                     /alternative_weights="1794.9"
                     /alternative_weights="1813.0"
     misc_feature    30185..30203
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 16.77"
                     /tool="antismash"
     misc_feature    30607..30622
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.5"
                     /tool="antismash"
ORIGIN
        1 gggccgcgca ccgctccact cgggaggaca cccccgaggc gctggtggag accgggcagg
       61 agtgggacca cgccatcgcg tcctcgccgg tgcgggccgt gctcacgggt gagtcgctgg
      121 tgctgcacaa ggacgatcag gcctttcgcg cctgggcgga gcaggaaccg gagcgagcac
      181 gtcacgccag ggagctgggg gtgcactcca tcctgtccgt gccgctgtcg gcgcgcgggg
      241 tgacgctggg ggtcgcgcag ttcctgcggt accggcgccc ggatccgttc acgccggacg
      301 acgtactggt ggcccgggag atcgtggccc gggccgcagt gtgcctggac aacgcacagc
      361 gtttcactca ggagcgggag acggcgctgg cgctccagcg cagcctcctg ccgcggacgc
      421 tcccgcaacg cagcgccgtg caggtcgcct cccgctatct ggcggcggcc gggcggaccg
      481 gtgtgggcgg cgactggttc gacgtgatcc cgctgtccgg ggcgcgggtg ggactgatcg
      541 tgggcgacgt ggtggggcac ggggtgcagg cttcggcgac catgggccgg ctgcgtaccg
      601 cggtacgcac gctcgcggac gtcgatctgc ccccggacga actgctcacc catctggacg
      661 acctcgtgct ccgtctctcc gacgagaccg ggggagagga gccggccggg gacatcggcg
      721 cgacctgtct gtacgcggtc tacgacccgg tcgccggcgg ctgcacgata gccagggccg
      781 ggcatccgcc ccccgtcctg atcgacccgg aaacgggtgg cggaaccacc atggagctgc
      841 ccgctgggcc gccgctgggt ctgggtgggc tgccgttcga gtcagcggag ttctcgctgc
      901 ccgagggctc ggtgctggcg ctgttcaccg acggcctggt ggagcgccgc gaccgggaca
      961 tcgacgaggg ctaccgactg ctgcacgagg cggtggccgc cccgccgacc gcctcgctcg
     1021 acgcccagtg cggggcggtc atcgaggcgc tgctgccggg cggggcgccg gacgacgacg
     1081 tggccctgct gatggcgcgc acccgggtgc tggacgcggc gcacgtggcg acgtgggaga
     1141 tccccgacga cccggcgagc tgcggtaccg cccgtaagga catcgacgag cagttgacac
     1201 ggtgggagct ccaggaagcg gtgttcacca ccgagctggt ggtcaccgag ctgatcgcca
     1261 acgccatccg gcacgcgtcc ggccccatcc ggctgcggct gatcctggac cgcacgctca
     1321 tcatcgaggt ctccgacacg agcagcaccg ccccgcacct gcgccgggcg gccggtttcg
     1381 acgagggcgg acgcgggctg atgctggtcg ctcagctgac ccagcgctgg ggcgcccggc
     1441 actcgaccga cggcaagacc atctgggcgg aactccagct gccggacaac tacgcggggt
     1501 tcgacggagc ggccactcgt tgaaccgtga tctcgtccag ttcgccgacg acgctccgca
     1561 gccgcctgct ccggtcaaga agcccccttg gacctcatcc ggcacgtgac tgatgccgac
     1621 cccgggctcc gggccgggac aggaagtgac gggccggccc ggtgccacgg tgccagatgc
     1681 ccctcaccgt gacagccctg gtcgcagggt ctcccatggc gacccgggcc ccgtcggcaa
     1741 ggcccgaccc cgcgtcgtgc cgcgcgcctc cggggcgggc cgaaggggag aagccctcac
     1801 cgcggccagg gcggcggtca gccgcactcg gcggaggcac ggcccttcat gatcgcctcc
     1861 tgggtgagcc acaggccgtc gatcttggga gagggcacca tgtcgagcgt ccagtgccac
     1921 aggttcgtcg ggcccgggtc gcccgtgaag gtttcaccgc tcgcctcgtg cttgcccttg
     1981 accttgctct catcgctgca gaaggtgacg acgtacccgt ccttcttccc gggccgcacc
     2041 tcggcgcggc tgtgctgccg ctcgccggca atcgtcaggc cgccgtcgac gtagacgccg
     2101 atccgggcct tcgcgtactt ctcggcctgg ctgccgggca cggcgtagta gccgtacgcc
     2161 tccgactcgg ggtcctgctc agcgatgccg aagacggtgg acttggcgta gagccgggcg
     2221 tcccggagag ccgcagcctg gtcggggtcc ttcagcttcg tctcctcgaa ggtgaccttg
     2281 aggtcggccg gcagcttcat ctcgggcccg ggcggcgggc ccgacagcat tgttgcccct
     2341 gtcgaacgga tgacctgggg gcggtgtcac cgggtccgaa acgtgccgtc tgaggcactg
     2401 gtcaagggct gccggccgcc cggcctcggc gttccgtccg ggccgtgacg gtctcgtcgg
     2461 agtgcggacg cgcctggcac cggcagacgg cttacacctc aaggccgcag gagacgttgc
     2521 ctctctgact gattcatcag tcaggacctc aatctgctct cttaacagct actccaccct
     2581 cctcgggtgt tgagattatc gcaatgcact cctagggtgt tgcctgtgaa gagcgacgag
     2641 ggcccgacga gcgcaccgac tgccgacgcc gccgttcgcg tccgtgcggt catcgcgaac
     2701 gcgggcgtca gccagcgcga gttcgcgcgc cgtgtcgtga tggacccgtc caagctctcg
     2761 cgtgcgttga gcggcacccg ccgcttcacg gtcgcggaac tggcgcggat cgcagacgaa
     2821 gggcgggtcg acgccgactg gctgctcggc agccggccgc gcgagaaggg aacggcgccc
     2881 gccgtcggca tcgagggcgg gcgaccgctg cagatcgtcc gcgagacggt ccggctggtc
     2941 gcggagcgcg gtttccacgc ggtgcgggtc gccgacatcg cccgcgcctg cgccaccagc
     3001 agtgccgcga tccactatca cttcccgggc cgcgccgagc tcctggaagc agccgttcgc
     3061 tggtgcatgg acgaggacac cgcgcgccgt gctgcccacc tcgccgaggc ggacgacgcg
     3121 gcggcggagc tgcgccagct catcgcgctg cagacgccgc gcaccgctca gcagcgccgc
     3181 cagtgggcgg tgtggctcga cctgtgggcc gaggccgccc gctccacggc ggtgggccga
     3241 ctgcactccg agtactaccg gcagtggcgg gaaaccgtca ccgacgtcct gcgcaggggc
     3301 gtcgggcagg gggtgttccg cgccgggatc gatccggatg cggcggcact gactctgacc
     3361 gctctgatcg acggcctggc gacccacgtc ctctcggcga gcgggccgtc ctccgccacg
     3421 gccgccgacg cgatgcacgc gacactgacg gcccacgtca cccacacgat cctggctccg
     3481 tagcccagaa gccacggaag ccccgccccc tgccccgcca tcgccgcgga gacaagaatc
     3541 cgggaggcct ccacatgccc atgaccgaga acgtcatcat cacctgcgcg ctcacgggcg
     3601 ccggcgacac cgtccgcaaa agcccccacg tccccgtcac cccggagcag atagcaagga
     3661 acgccgtgga ggcggccgcc gccggagcgg ccgtcgtcca catccacgtg cgcgacccgg
     3721 agaccggcgg cccgtcccgc gacccgaagc tctaccggga ggtcgtcgag cgcatcaagg
     3781 agaccggcac cgacatcgtc atcaacctca ccgccgggat gggcggcgat ctggtcatcg
     3841 acccggacga cccgctcacc cacctccccg gcaccgacct cgtcggcggt ctggagcgcc
     3901 tgccgcacgt cgaggacctg cttcccgaca tctgcacact ggactgcggc tcgctcaact
     3961 tcggcgacgg ctccaatctc tacgtctcga cgcccgacat gctgcgtgcg ggcgcacggc
     4021 gaatccagga gctgggcgta cggcccgagc tggagatctt cgacacgggc cagctctggt
     4081 tcgccaagca gttgctagct gaggggctgc tcgacgaccc gaccgtgttc cagctgtgca
     4141 tgggtgtccc gtggggtgcg ccggcggatc cgggagtgct ccagtcgatg gtcaacatgc
     4201 tcccggatgg tgcgcgttgg gcgagcttcg cgctgggacg gatgcagatg ccgtgggtcg
     4261 cgcagtcgat cctgctcggc ggccacgtcc gcgtgggcct ggaggacaac ctgtacctcg
     4321 gcaaggggaa caaggcgacc aacgcccagc tcgtcgagcg tgccgtgacc ctcaccgagt
     4381 cgatcggcgc acgtgtcgcg acaccggacg aggcccgcgc cacgctcggc ctcaagacgc
     4441 gcaagtagtc cgcggtgacg acgaagggcc ccctcatgac ctcacccgag aagacctcgc
     4501 ccgacccgac gtccccgaag acgacgtcat ccgggatcac ccctccggag aacgtccgcc
     4561 gcgtggcctg cgtcggcgcc ggagtcatcg gcggcggctg ggtcgcccac ttcctggcgc
     4621 gcggctacga cgtgaccgcc tgggaccccg cgcccggcgc cgcgcagaag ctgcgccgcc
     4681 tggtcgacgc cgcgtggccg gcgctcacct cgctcggcct cgccgagggc gcgtcggccg
     4741 accggctcac cgttgccgcg accctcgaac aggccgtggc cgacgccgag ttcgtacagg
     4801 agagcgcgcc cgagaagctc gacctcaagc gcgatctgct ggcccgtctg gacgcggcca
     4861 cgccgcccgg cgtcgtcatc gcctcctcca cctccggcta cccgatgacc gacatgcaga
     4921 ccacggccgc cgatccgtcg cgcctggtcg tcggtcaccc gttcaacccg ccctatctca
     4981 tcccgctcgt cgaggtcgtc ggcggcgagc gcaccgacgc ggcggcggtc gcctgggccg
     5041 cccgcttcta cgagagcgcg ggcaagtccg tcatcacgat ggacaacgag gtgcccggct
     5101 tcatcgccaa ccgcctccag gaggccctgt ggcgcgaggc gctgcacatg gtcgccaacg
     5161 gcgaggcgac ggtccgcgac atcgacctgt cgatcaccga ggggcccggg ctccgctggg
     5221 cggtgatggg gcccatgctg accttcgcgc tcgccggcgg cgaggggggc atggcgcaca
     5281 tgctggacca cttcggcccg tccctgaagt cgccttggac tcgcctcgaa gcgccggagc
     5341 tggacacgga gttgtacgac gccgtggtga cgggctgcga cgaggccgcg ggcggccgca
     5401 ccatcgcgga cctggtggcc gaacgggacc agggggtcat cgaagtgctg cgcgccaccg
     5461 gccgtctggg gcgcgagggg ggcgcccgat gacgaggctc cctctgttcc acagcacggt
     5521 ccgcccggag tggatcgact acaacggcca catgagcgag gccttctacg tcctcgtctt
     5581 cggtcacgcc accgacgcgc tgatggatga gaccggcctg ggctccggct accgcgagtc
     5641 cacgggctgc tccctctaca cggtcgagtc tcacatccgc ttcctccagg acgtgtccga
     5701 caccgcacac ctggccgtcc gcacccgcgt gctgggggcg gcagtccgca aggcgcactt
     5761 cgcgcacgag atgtacctgg tgtccgaccc ggcgtcggag ccggcgtccg ccgcggctcc
     5821 ggtggcgacg acggagctgc tcgcggtcca cgtcgaccag cgggcgggcc gggccgccgc
     5881 gttcccggac gcggtcaggc gccgtttcac cgagctgacc gagccggctc cggtctgggc
     5941 gggccgctcc atcgccgccg tggcctgagg tgtacagggg ctcgaaccgc gtgtcgggcc
     6001 cctgtgcctc cccggcgcca tcaccgccgg ggcgaacaac tcccgcgcga cgcgcgcctg
     6061 ctgggtcgac ccgtccgtcc gggtgaaggc gactaccggc ctcctcagcc atccgatgcc
     6121 gacctggcga cgcccggaag gtcactcact cccctccctg accgtgatcg tccacgaccc
     6181 cgtcggccgc ccggcagagg ccgaagccgc atcgcaccga gtcctggccg cacggccgcg
     6241 gacctgtcgc cgtcatcgcg cccacaccac tgcccggctc gccctcgccc agctccgtca
     6301 cggcgacgcc gagcagatgt gcgcgaccgg ccgcctcttc accagcacgg ccgacaaccc
     6361 acggccgggc cgactacgct tgctcatcgg cgacttccga agtcacctgg tcgctcacgc
     6421 cttctccgcg cgccgtggct catcctcgtg gacgtcgtgg acgtcgtggg cgtcgcggtg
     6481 ttggtcccgg gcgcggtgct gcgggaacga cagggatgtc cggcccagcc gatgaggcga
     6541 tggggccagg cggcgtcgga gcgcgacagg atcggcacct tgacctcgcg cgctgaagga
     6601 cgagcacagc agcctgtcat ccgcagtaac tacagtgaac agagaatgag gccccgtgcg
     6661 gtgggacgcg gtgcctgggg gaggggaccg agatggccag gaatccgtgg ataccgcgac
     6721 cgacgtccgc tgtcgcggtg atcaaccctg acgcgcccga agccgacaag cagcttctgc
     6781 ggactgctcg acgaaacccg gccgctctcg acctttccgg ctcgggcgca ccgacccaca
     6841 ccaagcgcat cgtggtcgcc gtcgtctcga ccaccgcctt gggggcctac ttcgtcacgc
     6901 atcgtttcgg ctccagcgac cgcccgattc cgggcgtgct tctcgccagg atccatgacg
     6961 ccctctccac cgccgagacc gtcatcgggt ggggggctct ggtcgccgga atggccaccg
     7021 cggcgtacgg ggtcctcctg gtgaccggcc gcgcccgcag aaggcggctg accgaaaggt
     7081 actgggcggc cgtccgcgac cacgtcgtcg atccggagga gctgacggac gagtgccgcg
     7141 ggctcctggc acgtggccag caggcgacca ccacggtcat gagatcgcgc gtccaccgcc
     7201 acggcctgat cgacaaggcc cacaacgagg cggcactgcc tcgccaggaa tgggagctcg
     7261 ccaccactct gcgcgactac agccgcctcg ccggagccga acccggcaag cccgccggcg
     7321 tcgaggtcgt caccctcctc cagcggcgac gcgacgccct gcgggcaagc ctggacggcg
     7381 tcgaacggcg cgttgtggcc ctggagaagt acgccgacca ggttgtggaa gccgaccggc
     7441 ggtacgagga atggaagcag atcgaggagc tgtccgagga cgcggacgct gtactcgatc
     7501 tccttgcccg gacagcgcgg gacgacatgg ccgtggccga gatcgaggga ctgaccggcc
     7561 aggccgctgc cgtggcggag agcctgacga ccgcgctgga atccgcgagg aaggccgcct
     7621 tcgtcgccct gccaccgccg gcggccacag cctgaccact gcaccgcaga agccggtggg
     7681 ggccgggccc gggtatgagc cgatcaggca ggcgctcctg gcggtcggag tcgccgagag
     7741 cgcgcgtcgt gtttcagcgg gccccgcctt cggcgctcgc ctcacgctcc tgtgtgtgaa
     7801 cgtccggtgg gggcgacagc ggccctgttg cctccgtcac cgggccttcg gcgccggccg
     7861 acggtgtgac gtggcgcccg gtgtcgctct ggtgaggcag cctgttgcgc ccgagacgtt
     7921 cgtgcgcgct ggcgaaatcg tccgatacgg ccgcggagac cgtcgacagg tccaaggcca
     7981 gagcgaagcc cgcgatgatc tccgccagcc ggacggcact tcccgggccg gtgcatccca
     8041 tgagcgccaa catctcgtgc tgcgtgggca gatgggtgcc gcctccgacc gtgccgagtg
     8101 ccagacccgg cagggtcatg ctcgcgtgga ccccgtcccg cgtgcgttcg aggacgaaat
     8161 ggcccatgcc cgactcgtgg acacaggcga tgtcctggcc ggtcgcggtg aagatcgccg
     8221 ccacgacgtt ggccgagttc gcgttggagc ccagcatcgc gctgtggacc gccccggctg
     8281 cgatgtgctg atacccgcgc accagctcgt caggggtggt tctgagtacc cgttcgatca
     8341 cacctgtcgg cagtacgcag tcagcggcca ccctgatgcc acggccctcc gccatggcca
     8401 gggctgacgc cttcttgtcg ccggacgagt tcccttcgac gaggaagaat tcgagtgcgt
     8461 catccgtgac caggtgcgac tgccgcaaga tccactggca cgcgtgccag gtacagacag
     8521 tcgtcatgtt ctgccctgcg gcatccccgg tggtgtacct gaacctcagg tgaacggccc
     8581 tgcccaggat cacgggttcg atcgagacga gcaccgcatg gctggagacc tgccggacgg
     8641 ccgtccggag gtcgccgatg tgctggggga ccgtcgcggc gaagcggctg gcgtctgcca
     8701 ggcgggagaa cgcgaagacc ggggcacgcg tcatcgcctg tgagaccgcg tgagtgctga
     8761 cgccgcccgc catcgtgacg gccagggccc cacgtgtcgc tgacgagacc agggcacctt
     8821 ccgtggtcgc cagaggcgcg tacctctcac ctcggacgtt cgtcccgcag aacagcaggg
     8881 gcccggccac tccgatcggg atctcgacgg cgccgacgag cccttcgatg ttcccggtca
     8941 gcttgccggc atcgagccgt gtgtgctgta gggagttcaa cgttgactgg gtccttgcac
     9001 ggagccagct cagcctttgc aggcgcgccg cctccgtgta gaccccgcgc gcgggcacga
     9061 accgcccggg agggcgcggc ggaacgggcc gaccggaagc ttctccggaa ctcatacagc
     9121 agcacccttc ttctgcggcg gtccgaccgg gggagagcgg ttcacaccgc tggtcgcagt
     9181 cggggcgagg agtggccccg tccacaacgc gtctgcgggg ggaccctgtc gccagaccgg
     9241 cgacgtgacg ttccgggcag ggacttggct tcggacgcgc tcacactgct ccccaccccc
     9301 gtgcccggcg gcaggcccgg tgccagctca acgacacggc tgcccaccgg ttacgcgagt
     9361 tcaccccgcg gcagctcccg gcacccccgc aagaggaagg gcggcaccca cggcccgaac
     9421 ccgggcgacg aggtggagtg acccctgccc gccccaggac acgggacggc gcggaagccg
     9481 gtgctctgcc gcgcgcgatc gtcggatgcg caccgggcag gcacagaccg cacggagcgc
     9541 aggaaattct cgacgtgctg ctgaccttct tgcaccggga ggcgggcccg gcgggcgccc
     9601 ccgtcctcct gctgccgcac gggtgcccgg cagctcgcac acgttccggc acctgctccc
     9661 ggcgccggcc ggtgcgtacc gggtgagcgc gcccggcccc atccgcttcg ggcactcctc
     9721 ggcgccgggc gtgacggagt tcccgtccac gtgcggggcg ctcgccgagg ccaccggcgc
     9781 cttcctggca ggtctcggcg tggagagcct cctggacgag gtggccgccg ccctcctccg
     9841 gctccgcccg cgcgtcctgg ccgcgaccgc cgaggggcga ccgactgcgg gccgcccaga
     9901 aagatggggg accgaccccc atgtgccccc accctccgcg cggcacgatg gggcacgccg
     9961 cgggccgaca ggtcccgcgt cggaccgagg gggtgggacg ttggagcgga acgcttcggg
    10021 accggggtgc ggcgccgccc gccccggtcc gggaccggac cccgccggac ggggggcggt
    10081 cgccctgctc gagaacggtg agcagcgcac ggcgagcggg gcctggtggg caccggccct
    10141 gcgcacggag gagcgggccg gggggatacc ggactgggcg gagtgggtcg agcaggtgct
    10201 cgctgccacg cctgccgccc tccccctccc cgaggaggag tacgaggggc tcagcggctt
    10261 cgagcgcgtg ctcgcaccgt tcgccgaggc ggcgggggac cggatggcgg cggctctcgg
    10321 gggcgaggag cgagggctcg tcgacctcgc agcggtccgc gccggcctgg tccgggcggt
    10381 cgggccgcga ctggcccgga tcgccgcccg tgtgctcgtg accgaactgc accgggcacg
    10441 agaggcgggc gggctcaccg gtggggacag ccgggcccgc ttccgggagt tcctgcggcg
    10501 ggcggggggc cggcggggcc tcgccgctct gctgagggcc cacccggtgc tcgcccggct
    10561 gctcggccgg gtcagcctcg acgcggccga cgccttcgcc gaactgctgc gccgcctcgt
    10621 cgccgaccac gtggccctgg ccgaggccgg gctcccgtgc gggtcggacg atcgcctgct
    10681 cgtcgacgtc gaggccgggg cgggcgacag tcacggcggc ggccggacgg tggcgctgct
    10741 gcgtttcgcg gacggcacgc ggctggtgta caagccccgc ccggtcgccg cgcaccgcca
    10801 cttcaacgac ctcgccgact ggctcgggcg cctgcccggc gcgccccggt tgcgcacgct
    10861 gaccgtgctc gaccggggga cccacggctg ggtcgagttc gtggaggtgc tgccctgccg
    10921 gaccgagccg caggtgcggg agttctaccg gcggcagggc gcgctgctcg ccctgctgca
    10981 cgcactggac gggaccgacc tgcaccacga gaacctgatc gcccacggcg agcatcccgt
    11041 cctggtcgac gtggagaccc tcttccaccc ggccctgccg atcgccgcct ccgacgaccc
    11101 ggcgagcagg gcactgcacg actccgtcca ccgggtcggc ctgctgccgc agttcctcct
    11161 cggcgacgac agcgcgctcg acatgtcggc ggtcggcggc ggccgcgccg cgctctcccc
    11221 cgtggcgctc gccgggtggg ccgactgcgg gacggacacc atgcggctgg tgcgccgccc
    11281 cggccggttc cgggagtccg ccaaccggcc ccgcctgcac gagcggaccg ccgaaccggc
    11341 cgcgtacacg gccgagttgt gcgaaggctt ccgggcggcc tacacggccc tcggcgaggc
    11401 gcgcgcggaa ctgctcgggc ccaccgggct gctggagcgg ttccggcggg acgaggtgcg
    11461 cgtggtggcg cggcccaccg ccgtctacgc caccctcctc gacgagacca cccaccccga
    11521 gctgatgcgc gaggccggcg cgcgggacgc cgtcctcgcc cggctgcggg agggcacgct
    11581 cggccacccc gccctgcccg ggctcgagga cgaggagatc gcccagctct ggtcccacga
    11641 tgtgcccgtc ttcgccgtcc gggccggcgg caccgccctg accggggtca ccggccgcgc
    11701 cgtgcccggc acggtgccga tctccggact ggcccgggcc accgggaaga tcgcggccct
    11761 cgactccgtg gaccggcagg accaggagtg ggtgatccgc gccgcgatgg tctccgcctc
    11821 caccacgccc gcccaccacc cggccgggcc cgggcgcggc ccccggcccg ccttcgcccc
    11881 cgagcccgaa cggctcctcg ccgccgcccg ctccctcggg gaccagttgg tctccctcgc
    11941 ctaccgcgcg gcggaccgcg ccaactggct cggcctggaa ctcctgggcg accgctactg
    12001 gcggctcggc ccgatgcccg ccgacctcgc ggccggctac tgcggccccg ccctcttcct
    12061 cgcccagctc gccgatgtca ccggtgtcgc ccggtacgcg gagacggcga gcgcgtccct
    12121 ggcgccggtg gcgggactgc tggacgccct gcacgaggac cccaccgcgc cgcccgccgt
    12181 gggctcgggc gccttcgccg ggctcggcgg gctcacgtac accctgctgg aggtggagcg
    12241 gctgctcgga gagccggcgt gcgccgagtc gcttccggcg gcgctgcggc tgctggaggc
    12301 agccgcagcg ggcgagcgtg agaccggcgt cggcgccggg acggccggcg ggctcgcggt
    12361 tctcctcgcc gcacaccggg ccaccgggcg gccggagacg ctgcgtgccg ccggacggtg
    12421 cgcggaacgg ctggcggccg ccggaccacc cgccgggccc ggattcctgg acggctcggc
    12481 cggtacggga tgggcactgc tgcggtacgc cgagaggagc ggggccccgc gcttccggga
    12541 ggcggggctg gaggcgctcc gcgaggccgt cgccgcgctc ccggcggcga acggcgccgc
    12601 tgacgaaggc tggtgccacg gccgggccgg catcgccctc gccctcgccg acagtcccgc
    12661 cgctctcgcc gaccaccggc tggccgcctg gctcaccgcg acggcccgcc tgctgcgggg
    12721 cgccggaccc cgccccgacg acagcctctg ccacggggag gcgggcctgc tcgaactcct
    12781 cggccacggc gccctggccg gagcccgagc cgggctcgtc caccgcaccg gcgcgctgct
    12841 ggcctcggtc gaggacggcg gaccgggctg cggtacaccc gaccacgtcc cgcacgcggg
    12901 gctgctcacc ggcctcgcgg ggatcgggca cgggctgctg cgggccggat tccccgaccg
    12961 cgtgccctcc gtgctcctcc tcgacctgcc caccctgacc gcggcccccg accaccaccc
    13021 ctgaccgcgg cccccgcacg caccaccgca ccgacagccc gagcacctca cccgtcctca
    13081 cgaccaagga tcgaggcatc ccatgcagat cgacgacgcg gccacccacc tgaccggcgg
    13141 taccggcgag agcgccgggg aacacccggt cggcgccatc accctcttca ccaccggcgc
    13201 cctcggtctg cgctccagac tcctgagcgc ctcggagggc ggagcggcct actcccacga
    13261 actgccgtgg accaccatga ccgctccgca gtgacgccgg ggcccgtccg gagcggcacg
    13321 ccctgccgct ccggggcccg ctccagtagc ctgcgcacat gcgtgcgact tcctcggtca
    13381 tcgtcgggcg ggacagtgaa tcggctctgc tggcaaaggg gttggccgca gccgggcggt
    13441 cctcgggagg ggcggtgttc ctcgtcggcg aggcggggat cggcaagtcg cggctggcgg
    13501 gccagtgcgc cttcgacgcg tacgcccgcg aggtgcccgt cctgcgggga cgtgccacct
    13561 ccaccgggct cgtcgtgccc taccggccgc tgatggaggc cctctcctcc cggttccggg
    13621 ccgcgggcac ccccgaggaa ccagaactgg agcccttccg gcccgcgttg tccgcactcg
    13681 tgcccgaatg gcggcggcac ggccccgagt tccccgcctc cgtggtcgaa ctcgccgagg
    13741 ccctgctgcg tctgctctcc gtcctcggac gggagcgcgg ctgcgtcatg gtcctggagg
    13801 acctgcacga ctccgacacc gagacgatcg cggtcgtcga gtacgtcgcc gacaacctcg
    13861 cggacctccc cgtcctcctc ctcggcaccc tccggcccga gccgggcccc gccctggacg
    13921 tcacccgggc cgccgccggc cggcagaccg ccaccgtcct cgaactcggc ccgctggacg
    13981 acacgcaggt gcacagaatg gccgaggcgt gcctgaacgc cgcccccggc gaggtgcccg
    14041 ccgaggccca ccgcaggatc gcgcgccgcg cgggaggcaa cccgtacctg gtggaggtgc
    14101 tcctcgccga cctggtcgac tccggcaccc tgcaccgcac ggacggcggc tggcggtgcg
    14161 aggacgggcc ggacggcggc gtccccaccg gcgtcgtccg cagctgggcc gcccgcctgg
    14221 accgcctcga cccacccgtc cgcgaactcc tgctcacctc cgccaccctg ggcagcacct
    14281 tccaggtccc cctcctgcag accgtgctcg gctacgagga acgcgccctc ttcgcccatc
    14341 tgcgcgccgc caccgaggcc ggcatcatcg ccccggacgg cgcggccccc gaccggtacg
    14401 ccttccggca cgcgctcacc gccgaagccc tcaccgccgc cctgctcccc gccgaacggg
    14461 ccgccaccgc ccgccgggcg gccgacgccc tggaggaact ggggcccgcc atgagcgagg
    14521 acgcccgtca gctcctcgcc accctgcgcc tggccgccgg ggacgccgcc gccgcgggag
    14581 cgcacctcgc cgaggccggc cgccggatgc tcggccaagg cgccgcgggc tcggcggccg
    14641 tgctcctgga acgcgcccac ggactgaccc ccgacgcccg ccgccccgag gtcgccgcct
    14701 cactcgccgt cgccctcgca gaggccgggc ggctcgccga ggcgttcacc ctggccgcgg
    14761 ggctgccgcc ggtgccgccc ggcacaccgg ccgccgccga gcgggccgac gcgcacatca
    14821 gggtcgcctg ggccgccgtc atgggcgagc accccgagga ggccgggcgc cgggtgcgcg
    14881 ccgcccgcgc cctgctgggt cccgcgccgc cgcccgcaca gcaggccgcg ctcgccgtgg
    14941 tcgagggcca cctcgtgctg cttcccggcg gcgcgggcga ggagggcacc gccgacgccg
    15001 ccgaagccgc ccgccgggcc gcggccgtcg ccgaagagca cggcctgccg gtggtcgcct
    15061 gccaggcgtg gcaactgctc gggctgctca gccgggacca gggcttcgac gaggcagacg
    15121 cctgcctgga gcggatgctc gccgtctccg aacgccacca gctcgccgcc tggcgcatgg
    15181 aggccctggt ccggctcggc gccaacgcct tcctgcgcac gggcgacgcg acccggctgg
    15241 cggccgcccg taccgccgcc ggagagctcg gcgccctcgc gctgacccag accgtggacg
    15301 ggctgatcgc catgaacgcg gtgctctgcg gcgactggga gaaggcccgc gccaccgtcg
    15361 accgctcggt cgacgccgcc gcccgggtac gcaacctctc cgcccaccgc tacctcctcc
    15421 tcgccgacgc cactctcgcc gcccaccagg ggcgccgccg cgagcgggac gccgccctgc
    15481 tgcggttccg gcgcgccggc ggcgaggact cgctcctggt gccgctccag cgtggcctgt
    15541 gcctggccgt cggcgccctc ctcgacgagg accgccccgg cgccctggac cacctggagg
    15601 ccgcggtcgc ctgggaacgc gaacggccca gcctgtactt cctcggcggc cgctggggcc
    15661 tgctccccct gctgcgcgcc ctggacggga ccggtgacac cgcggaccac cgggcggccc
    15721 tcgcctcgca cggcgcccag ctcgcctgga acaagctctt cctcggcatg gccgacgcgg
    15781 tccaccgagg acgcggcggc gacgcggcgg gcgccgcgga agcggtccgg tcggccctgc
    15841 gcaccgggga ggcgttcccg ctcgcccgcc acctcgccct gcggctggtc gcggaggccg
    15901 ccgtcgccga cggctggggc gagccggtga cgtggctgcg gaccgccgag gagttcttcc
    15961 acgcggccgc ggtccagccc gtcgcctccg cgtgccgcgc cgccctgcgc agggccgggg
    16021 ccagcgcccc gcagcgccgc gacggccgcg accgcatacc cgccccgctg cgcaccagcg
    16081 gtgtcacccc gcgggagtac gaggtgttcg tcctcctcgc ggaccgtccc ggtaaccagc
    16141 agatcgcccg gcacctctcc atctcccccc gcaccgtcga gaagcacatg gcgagtctgc
    16201 tcgccaagac cggccgccag gaccgcaccg ccctctgcga gttcgcggcc gagtgcgcct
    16261 cggccgcggt gcgccgctga ccggtccacc tgggggccgc gggggatttt cgggcgggga
    16321 cccggcggaa aggtaggggg aacgccccga tgccgtaccc gggcccgccg ggcagcatcg
    16381 ccgtcgggca cgcgtgacca ccgtgcccga ccaacggagc tgggaggccc gcccgtgacc
    16441 cctgcgcccc gcaccagcgc gcacccgtcc cgaccgcact tcaccgtcct cgggcccctc
    16501 gccgcccacc gcgacggcgt gccgctctcc ctcgggccgc tcaaacagcg cctcgtgctc
    16561 ggcctgctgc tcagcagacc caacaccccc gtcggcaccg acgcgctcac cgacgccgtc
    16621 tggcccgacg acccgccgcg caccgctcgc aagaacctcc aggtgtacgt cagcagcctg
    16681 cgtaccctgc tcggtgacgg ccgcaccgcc tcacccggcc tcctcgtcca cgactgcggc
    16741 ggctacgtgc tgcgcgtgga ggacgacgag gtggacgcct tgcggatgcg gcggctcgcc
    16801 cggtccgcgg ccgggctcga accggcctcc gccgtcggcc tgctgcgcga ggcggtgggc
    16861 ctgtggcaga gcacgcccct gcacgatctg cggcgctctc ccgccctcgc ggccgagggc
    16921 gagcgcctgg agcggcggtg cctgtccgtc cacgaggagt gggccgagtg cgaactggcc
    16981 ctcggccgtg gcccggccgt cgtggaggag ttgcgcgagc tggccgagcg gcacccgctc
    17041 cgtgaacgcc tgcacgcggc ctggatgacc gccctgcacc agtccggacg ccgctccgag
    17101 gcgctggccg tctatgacga gtaccggcag gaactggccc gggaactcgg tctggagccg
    17161 ggcggcgcca tggccgaccg ctaccgggac gtcctcaccg aatcccggtc ccacggcatc
    17221 gcgcggtccg cagcccctgc cgaactgccc ccggacccac cggtgttcac cgggcgtggc
    17281 ggccagctcc gggaactcat cgacgcgctg gaccggcccg gcggggaggg cgggaccgtg
    17341 ctgctcaccg ggccggcggg cagcggcaag accgccctcg ccgtacgggc cgcccggctt
    17401 ctcgccgacc gctaccccga cggccgcctc ctggtccggc tccgcgacag cgccggcgcg
    17461 gcccagccgg ccaccaccgt cctcgaccgg ctggccggcc tcaccggtgt acccgcgacc
    17521 ccgcaggcgt ggcgtcgctg gctggtccgg caccgtgccc tggtggtgct ggacgacgcc
    17581 cccggggagc acaccgtgcg gggactgctg ccgacggacg gccggtccgc cgtcctggtc
    17641 accgcccggg gcctgctcgg cggtctcgcg ccggtcggcc gggtggacgt gccgccgatg
    17701 gacccggcgg aggcactcga cctgctggcc cggttcgtcg gcacggcccg tgtcgccgcg
    17761 gaccgcgccg cggcgctgcg cgtcgtgcac ggctgcgggc tgctgccgct cggtgtgcgg
    17821 gtcgccggta tgcgcctctc ggtcctgcgc cacctgccgc tcgcggagta cgcggaccgg
    17881 ctggccgacc ccgcctgcgc gctcgacgag ctctccgccg gggacgtcct ggtgcgcgac
    17941 cggctcgccg tggcctggcg cgacctcccg gcggcccagg cccaggccct cgccgggctg
    18001 gcctccgccg gcctggaggg gccgttcacc ctcgccgagg cggcggccgc gctggacagc
    18061 ccggtgcggg cggccctgcg caccgtggag gccctgatcg gcagcggagc cgtcaccacc
    18121 tcgggcgggg aggtcaccgc ccatgccgca cactacgaag ttccgcgcct gacctggctt
    18181 ctcgcccgtg agaacgccga ggagcggatc gggcgcccgg tcgtcgtgcc ggggtgagcc
    18241 cgtcacccca gagtgagcag ggacagcagt gccctcggcc ccgtgggcgc gcccggggcg
    18301 ccgtgacggg cggccagggt gtggagggcg agcaggagcc ccgccgaacc ggtcgccagg
    18361 tcggtggaga accggcgcag acccgcgccg gggaccagga ggtggtcgcc gtcctggacg
    18421 aggtgccagg tcaggttgcg caccgacgcc aggacgtcgg gcgccggtgc cgtgcgggca
    18481 gagccgtcgc cggacgccgc gtccagggcg tgcgccgtcg cggtcagccc ggcgcggccg
    18541 gtgaacagac ccggctcgcg gacgaactcc aggacgcacc cctggcgtac gccgggcagc
    18601 agcgccgaca gcagggcatc ctcgcggtgt tccagatagg cgcgggccac cagggcgaag
    18661 ccgccgctgc cctgatccag gtagagcagg tggcggcggc cgtccttgac ctggaccgaa
    18721 ccgcccggca tccgtacgca gtgcccggcc tcccggtgca gtacgtcccg cgcggcgtcc
    18781 agcaggtggc gctcacccgt cagctcgtac agctccaggt ggagcagggc ggcgccggag
    18841 aggccgcgga gcaggccggc ggagggcggc gcggtcagcc ccggcaccgt ctcgccgcgc
    18901 gccagtcgcg ccaggtcgct cgcggtgcgg aagacctcgg gcggcggaca ggcgcccggc
    18961 cctccggccg cccgtgtgac ccgcagggcc gccagggccc gcccggcgcg gcccgtcgcg
    19021 aggtccgctc ccgtcggcgg gggcgcggcc gaggcccgct ccagcagttc cgccgccgcg
    19081 tcgccctccc cggacgcggc gagcaccgcc gccgcaccgg gcaggccgtc caggagcccg
    19141 cccgcgcgct ccggcgggcg ccgcagagac gcatcggcga gccagcgcac ccactccccg
    19201 ggcacctcgg cgccgacatg acgcagggcg tgcagcactc cggccgctcc gtgcgccgcg
    19261 cacacgccgc cggaggcgaa cccgtcgggc ccgcccggga agagccggtc gagtcgctcg
    19321 ggcgtggcgg cggcacgtac cccggccacc agcatggcgc gcagccggtc ccagtccggc
    19381 tcaggacccg tcaggagccg ctccaccggg tcggtccggt ccatggccga ggtgagcggt
    19441 gccgggcgcg gcggtcccgc gtccgggccg agccggtagc ggtcgcgggc ccagcgctcc
    19501 aggaccaggg ccttgcggcg gtcgtggccc gccatctcgg tgagcggcat cagcatgtgc
    19561 agccacgtcg accacagggc gtacgcgtcg gcctccgggc ccgcggtgcc cgccggagcc
    19621 tgcataccga aggcgcccgc gaaggggctc gggtcctcca gctccgtcgc gtactcgaag
    19681 tcgatgagga ccaggcggcc gtcggggcgc agcacgatgt tggcggggtg caggtcgccg
    19741 aagcgcaggc cgcgggcgtg gacggcggcc aaggccgacg ccagccggtc cgtcacctcg
    19801 tccacccagg cgcggtaggc ggcgagttcg gcgtcggagc gttccccgcg gaccagggcg
    19861 taccgggcga cgatctcctc gaagagggtg cgcccctcga cgtgctcctc gaccaggaag
    19921 tggtgctccc agacggttcg caccccgtgc acccgtggca cgcactccag tccgtccagc
    19981 cgtcgcaggg cccggtgctc gcggtgcaga cgggtgaccg cgtcgtcgcc cgccgagtcc
    20041 aggccgcagt gcgggcgggc ctcacgcagg acgacccgct cgccgctccg gcggtgccgg
    20101 gcgaggtaga tgccgcccgc gttggagaac tggagggcgc gctcgaccac gtaggggaag
    20161 ccgtcgtccc gggccgccgc gcgggccgcc aggtgcgggc ccagctccgg cggcacggtc
    20221 acccacggcg gcacccggaa gaccacgtcg cgctcgtcgg ggaccagccg cccgtccggg
    20281 gcgcgcagcg ccgggaccgt gctgccgtcc gccgcccggc accagcggtc ggtgaaggag
    20341 ccgtaccgga cgtagacggg ggcgtcgccg atccgcaggt cgctgaggat gtaggggccg
    20401 cggcggccgt cgagcgccgc cgacagctcg gccaccagcc gcaggaaggc gggctcgtcg
    20461 ggcggatagg cggtgacgaa cttgccgctg ctgccgcgcg ccatgtactt gtcggacatc
    20521 agggcgagcg cctggcggct gcgcaggaac ttgaccggca ccccgtggcg caggcagatc
    20581 cgcacggtct cccgcagcgt cgaggccgcc tcctcaggga ccgtggagac gtggaccttc
    20641 cacccctgct cggtgagggg cgccccgtcg ggccgcagcg aggtccacag ccccgagcgc
    20701 cccttgcccc acccgggggg agccgcctgc tggtccagcg cgaacctggt cccctcgtcg
    20761 gggagccggg cgggcgtctc gtagtacgtc gggtcggcga gcgagtagag ctggttctgg
    20821 tggaggccgg gcacggtccg ccgcctttct gccggggagg ggagcgggtc gggtcagtgc
    20881 gggggagcgg cggccgcggg gtccgtcctg ccggtgccgg ggccgtcccc tccggcggcc
    20941 gggggcgggg ccggtttccc gggcgtcccc tcgtcctcgg ccgtcccctc gtgcgggggg
    21001 accgcgcggg ccgagggggc gaaggtcacc acggcggccg agaccgcgag taccgtgccg
    21061 atcgcggtga aggcgccggc cgggccgagg gcgccgagca gcgctccgcc cgccagcggc
    21121 ccgaacggct gcaccagtga ggagaggaac ccggccgaac tctgcacccg gcccacccgg
    21181 tcgtccgggg tcaccaccag cagcgtggac aggaagccga tgctggccac cgtggacagg
    21241 aacatgcagg ccatcaccag caccccggcc accaggggca cccgtaccac cgccagcgcg
    21301 ccggccgtcg ccacgcacag ccagcaggtg gccgggacga gcagcgcggt acgccgctcc
    21361 ggccgcagcc ggggggccag cagcgccccc gccagcgcgc cggccgaggt gcaggccacg
    21421 accaggccgc cgcccacccc cgaccggccg ctgtcggaga agaccgacag ggcggtgaaa
    21481 ctcatcgccc cgaaaccgaa gttcatcccc aggccgaaga ccagcagcac cgtccgcagg
    21541 tagggcaacc gccacaggaa ggccagaccg gccgtcagct cgcgacggct gaaggcgcgc
    21601 ccgggacggg ccgccgggcg cgagcgggtg cggaccaggg ccacgcacag ggtggagagc
    21661 gccagaccga ccgcctccgc gaggaacggc agcacggggt ggacgccgaa cagcgccccg
    21721 ccgatcagcg ggcccaccag ccgggcggtg gcggtgcggg cctggagccg ggccgtcgcc
    21781 gcccccatct ggtccttcgg cacgacggcg cgcatcagtc cgaacgcggc ggggccgtag
    21841 agactggtga tcaccgcgcc ggccgccgcg accagcagga ccagggcgag cggggcgtgc
    21901 ccgttccaca ccgcgacgac cagcgccgtc accacggtga ggctgccgag gtcgcagagc
    21961 cgcatcagcc ggcgccgctc cacccggtcc gcgaccacgc cgccgggcag catcgtcacc
    22021 agcagggagg cgacggagac cgtcccgatc gcgccggcct gcacggccga gccggtctcg
    22081 cgcagcacca gcaacggcag ggcgagtgcc gtcatctgcg tgccgatcac ggcgaagagg
    22141 ccgctcagcc agagcagccg gaagtctcgg ttggcgcgca gcgcgaccgc gcgctcgggc
    22201 tcggtcatgg gtcggctccc gtggggtcgg gtgaggtcag gacggggtcg cgaaggctca
    22261 cggggaacgc ggcgggcgcc ccgtggagag cccgtgacgt ccggcggggc ggtctccgtg
    22321 tgtacggagc cgccccatcc ggccggccgg gcgccacgcg gtggcgggcg cccggcccgg
    22381 acgtcacttc tggttctcga ccacgctgag gacgctgatg cagttgccgt cggcgatgtg
    22441 ctcctggtcc accgaggtgg tgccctgcag gtccaggacc gacgcgctgt gcgcctcgac
    22501 ctcgggggac tcgacggtct cgggggtctc ggggttggtc ttctcggaca tggtggtctc
    22561 cgtccactcg tggggtgccg catcggatgc gccgggggag cgggaaccgc ctcaccggct
    22621 tcggcgtgcc gtcggcctgc cgatgaccag aacgttagga agcccgtcct cactaacgcc
    22681 ccgccaccgg tatggcatcg cttaaccccc agcccgcggg ggcttccccg tccccggcgg
    22741 gagcccggac gccgcccgtc ccgggcccca cgggcccgcg ggcctcgggc cataccgttc
    22801 ggcaaccgct cctggaccgt tcgccaaccc cgccacgcga acctccatcg gcacgggtga
    22861 cgcccgcgcg gtcccggtcc gaggggcggc gcgcggccgg cccgcgcggg cagccgcgcg
    22921 gaccctgccc gccgcggcac ccgccgcgcg ggcggcggaa ggagcgacgt atgcgactcg
    22981 cggagatcat cggcctacgg cccgaaccgg cggccggcgt gctcgtcacg ctcacccgcc
    23041 gctgcccgct gagctgcgcc cactgctcca ccgcctcggg tccggacgcc gacgagcggc
    23101 ccgaccccgg cgacctgagg cgtttcgtcg cctcgttcac cgcccgcgac cgccccgaag
    23161 tgatgatgct gaccggcggc gaacccctgc tcatgcccgg cctggtgcgc gaactcgccg
    23221 cctcggcgaa ggagaggggg acgcgcaccg ccgtcctcag cggcatgttc ttcgcccgtg
    23281 cccggagcgt ccccagggcc gtgctgcgcg ccgccgccgc cgtcgaccac ttctccgcca
    23341 gcctcgacct ccaccacgaa cgcgaagtgc cccgcacggc cgtcttcgcc gccctgcgcg
    23401 ccctgagcgc caccggtacc cgcgtcagcc tccacctgac gggcaccgga cccgacgacc
    23461 cctacctggc cgatgccacc gccgccgtcg agcgcgagtt cggcggcacc ctgcccgtcc
    23521 tggtcaacga gatcagggcc ttcggccggg ccgccacctg ggcacggccg gcccgccccg
    23581 tcggcgggga cgacggggcc gcccccgcgc cctgcgcgat ggccgcctgg ccggtggtcg
    23641 ccttcgacgg gaccgtgctg gcctgctgca accagcacac cgtcgaccgc cgccccgtac
    23701 cgccgcacct gcgcctcggc cacatcgccg aggacagctg ggccactgtc cgcgcccgcg
    23761 ccctcgactc acccctgttg cggacggtcc gcaccgtcgg ccccctccac ctcagagccc
    23821 gccacgcccc cgacgcgccc cgggccgcct cctactgcga cgcctgccgc cagctctccg
    23881 cgctccccgg cgccgtcgcc gcagccgaac ggaccgcggc cggggcgacc ggcgcactcc
    23941 tggacctcac cgtcgggcgg tcccgtcgcg cccacggccc caccgccctg gtccgcgccc
    24001 acggctgcgc cgcgtacgcc gcctgggtgg agcggcccgg acccggcgaa ccagggaccg
    24061 tacggtgagc ggcggctcgg cctcgggccg tctgcgggcc aaactctccc tggtcgaggc
    24121 ggggccgcac ggcgccaccg ccgccctgtg gcaggccgac cgcccacggg accgttacct
    24181 ggcctacctc gtgacgatgc accaggtgat cagggcgtcc gtgccgctga tggagcgggc
    24241 cgccgacctc gcggaccggg ccgcccgctg tggtgccgac ccgctcgccg cccccctcgc
    24301 ccggtacctg cgggcccacg tcctggagga gaccggccac gacgcctggt tgctggagga
    24361 cctggccgcc gccggggtgg acaccaaagc cgtgctccgg gccgtccccc cgccggacgt
    24421 cgccgcgctc accggcgccc agcactactg gaccgagcac caccacccgc ttgccctcat
    24481 cggctacatc gccgtcctgg aggggcacgc gccggccgcg cgcctgggcg ccgtgctggc
    24541 ccggcgcacc tgcctgcccg aggcggcgtt ccgtaccgtc cgggcccacg cgcacctcga
    24601 cgcggaccac gtcgacgacg tgtacgccct cctggactcc ctgccgctga ccgggcggga
    24661 cgaggcgctc ctcgccgtca gcgccctgca caccgtggac gcgctcaccc gtatcttcgt
    24721 ccggctcggg cgccgcgcac cggccgccgt gccgctgcgg gagaccggac ggcccacacc
    24781 gacgggaggt cccggatgac accaccccag cgacccgatc tgctgacccg gctgcacgag
    24841 gcggggttcg cggtcgacct gctcaccgag gagcaacgcg aggtcctgac cggcctggaa
    24901 ccggaggaac tggccgtcct gctcgacatc aaggaacgac tcgacgccgt cggcccggag
    24961 gtgcaggcgc acggcgagat cgccggcggc gccctgttct gacgccccgc cggtcccggc
    25021 ccgcacccac gggccgggac cggcgcaccg gcgccgcccg cccgacgtcg ccccgccagg
    25081 aaggaccccg agagatgacc tgctccgcgt gccaccaggg gctccccgcg gacgcccggt
    25141 tctgcccggc ctgcgggacg cccgccgccc ccggcgcagg acggcccgta ccggccgccc
    25201 ccggcctccc gctgcccgag gacaaacgca agccggtgac cgtgctcttc tgcgacatgg
    25261 tcggctccac cgcgctctcc ggcgccctcg acccggagac gctgcgcacc ctcaccctgc
    25321 gctggttcgg gctgatgagc gcggagatcg aggcgcgcgg agggacaccg gagaagttca
    25381 tcggcgacgc cgtcatggcg gtcttcggcg tcccgcacgt ccacgaggac gacgcccgcc
    25441 gggcgcttgc cgccgccctc ggcatccgtg aggcgctgaa gcgcttcaac gccgaactgg
    25501 agcggaccct cggcctgcgc atcggcatcc ggatcggcgt caacaccggc caggtggtgg
    25561 ccggttccga cgccaccgcc cggcaggcgc tggtctccgg cgagacggtc aacgtggccg
    25621 cccggctgga gcagaacgcc ggtccggggg agatcctgat cggcccgcag acgctgagcg
    25681 ccgccggtcc caccgtcgcc gtcgaggagg ccggcccgct ggccctcaag ggcaagaccg
    25741 accgcgtccc cgcctaccgg ctcctcgccc tcggtgccga cgaccccgaa ctgctgcgcc
    25801 gcttcgacat cgccttcgtc gggcgccgca ccgaactcgc ccgcctggcc gaggaggcac
    25861 acgcggcccg gcgcggcacc aggctgctgc acctggcagg cgaagcgggc accggcaaga
    25921 cccggctgct ccgggagtgg cgcacccgcg ccaccggccc cggccacctc gtgcacgggg
    25981 ccggacgctg ccgaggctac ggcgaccacg gctctctcgc cccgctcgcc gacgcggtgc
    26041 gcaccgtcct ggccgaggca ccacgctccg ccgacggcca ccaggacgac atcgccctcg
    26101 gcgtcctcgc cgccggactg ctggacgacg gcacacccaa cgtgcccctg gaggagatgt
    26161 gcgcggccct cgccacggtc ctcgctcgca ccgcccgcac ctgccgcccg gtcctggtgc
    26221 tcgacgactg gcactgggcc ccgccacccc tggtacgcgc cgtcgaactc ctgcacatcc
    26281 ggctcgggga cgcacccgta ctgctcgtct gcgccggccg gcccggtggc gccgccccgc
    26341 ccgccaccgc gatcccgctg cgcctggaag ggctggaccg cgcggaagcg gcccgcctcg
    26401 ccgccgacct gatcggtgcg ccgcgcaccc cggtcgccgc ccggctgctg gagcgggccg
    26461 aggggaaccc gctctacctg gaacaactcc tgctgcccgc cgacgccggc acaccggcgc
    26521 tccccgacga cgagctgcca ccgaccctcc aggccctcct cggcgcccgg atcggcgccc
    26581 tcgacccggc cgaacgcttc gtcctcgaca tcgcctgcgt cgtcggccgc gaattcgacc
    26641 ccgccgaact ggcccgcctc gcggccaccg ccccgggcac ggcggccccg ccggacggcg
    26701 acgaaccgcc caccgtcctg ccggtgctcc agcgcctccg gcggcgccgc ctggtcgagc
    26761 cggtgggcac cggaccccgc agcccgtacc gcttcgccgg cggcctcgtc caggaggtgg
    26821 cgtacgcctc cctctccaag cggaccaagg cggaacgcca cgaacaggcc gcccggctgc
    26881 cgagcgtcac ccaggccggg gacgccgccg tcggtggtca cctggagcgt gcctgccgcc
    26941 tgcggaccgc gctcggcctc gtcgacgacc ggaccgcccg gctgcgcgcc cgggccgcca
    27001 ccgcgctcgg ccgggccggc gcccaggccg tggcccgctc cgacctcacc tgggccgaca
    27061 gcctgctggg ccgctccgtc gaactggccg agcccgacgc gcccggagcg gtcacggccc
    27121 tgcgccgcct cggcgaggta cgcgtcgcgc tcggccggac cgaggagggc accgccctgc
    27181 tgcgccgggt ggccgcggac ggagccgtac cggtcgaggc cgcccacgcc cgcctcgccc
    27241 tcgccgtcca ggaccccggg gccgcgctcg cgtcggtcgc ccgcgccgtg ctgcccgtct
    27301 tcgaggcggc cggtgaccgg atcggccagg cccgcgcccg gctccgtctc ggacagcaac
    27361 gccaggccac cggacgccac gaggaggccg accgcgaact ggtccgtgtc ctggaccagg
    27421 cggtcgccgc gggcgcggag cccgagcggg cggcggccct gggagccgtc ggcgtctcac
    27481 tgtggcgcgg gcccgaaccc gtcgccgccg cgatccaccg ctgccgggcc ctgctcgccg
    27541 ctcacggcga cggccggccc accgtcggcg tcaccctcaa ctgcccgctc gccgtcctcc
    27601 tcgccctgga cgaccggccc ggcgaggcac acgccgccct cgccgaggcg gcccggctcg
    27661 ccgccgaact cgcctacgcc gaggccggcg tcttcctccc ggtcttccgg gccaccgtca
    27721 ccaccctggc cgggcggcgc gtcgaggcct tgcggctgct cgccgacgcc gatgccgagg
    27781 cggaacgcct gggcgcgggc gggatgcggg tcgccatcgc gctggagacc gggcggctgc
    27841 tgctggacga ggggcgcgtc cacgaggcgg ccgaacgact cacgccggcc gtccgggccg
    27901 acgcgctctc ccgcgccgac accgtcgacc tctccgggct gcgggcccgg ctggccgccg
    27961 cctacggacg gggcgagagg gctctggccg ccgccgacga ggccgtggcc accgccgcgc
    28021 tgaccgactc gctcccgctg cgggcgacgg ccgccctcga ccgggcccgg gtcctcgcct
    28081 cgctcggcgc gcacgagggg gccgaggcgg aggcccgccg cgccgaggag cacttcagcg
    28141 acaagggcca cctgccaggg gcgcgggccg cccgagccct gctgggcggg cccgacggcg
    28201 gcgtccaggc cggtacgacc acgaccgaga aggcgagttg acccatgggg acgaccacca
    28261 ccggggcacc gcccgggacc gcgctgacct ggagcctgcg cggccggggc cccgacgacc
    28321 tgcccgtcgt cgccgacccc gccgcgccgg acggccccgc cgaggggacc gggcgcggcg
    28381 tgcgggtctg cgtcgtcgac tccggcgtgg agcgggacca cccgctggtc gggccactcg
    28441 ccggctcctg ggtggtcgtc aaggacgggg ccaccggtga ggccgaggtg cttcccacca
    28501 ccaccggcga cacctgcggc cacggcaccg cctgcgccgg catcatccgc cgcaccgcgc
    28561 cggagtgcga gatcaccagc gtccgggtgc tcggcgagcg gttctccggc accggggacg
    28621 tgctcctggc ggggttgcgg tgggccgtcg accaggggtt cgacctgatc aacctcagcc
    28681 tctccaccac ccggacccgg ttcgcccacc aactgcacga actggccgac cgcgcctact
    28741 tcgcccggac ggtgctcgtc gcctccgccc acaacacgcc ggtggagagc ttcccctggc
    28801 ggttcgcctc ggtgctctcc gtcggcagcc accaggagga cgaccccgca ctccacctct
    28861 acaacccgtc cccgccggtc gagttcttcg cccccggcca gaacgtgacc gtgccctggc
    28921 tgggcggcgc caccatccgc accaccggca acagcttcgc caccccgtac atcaccggtc
    28981 tcagcgcgcg tctgctctcg gcccgtccga ggatgacgcc cttccagctc aagagcgccc
    29041 tctatctgtc cgcggccaac gtgacgctcg ggccgcggca ccaccttccg gcaggagagg
    29101 catccgatga ctccgagaac tgaccccgtc accgccccgg tcccgcttcc cggcgccgcc
    29161 ggcgacgccc ggcgccgtga actcctccag tccgtcgtcg aggtggcccg cgccatcttc
    29221 ggcgcggcgg cgggctccgt cctcctcctc gacgaggaac gcgacgaact cgtcttcgcg
    29281 gccgtctccg gcgagggcga ggagttcctg gtcggcaaca ggttcccggc gggcagcggc
    29341 atcgccggct gggtcgccac ctcgggggaa ccggtcgtcg tcgacgacct caccgccaac
    29401 cgttccttcg accgctcggt cgccgagtcc accgagtacg tgcccgacgc cctgatggcc
    29461 gcacccctgg tcagcgacgg ccgggtgctg ggcgtcctgg aggtcctgga cccgtccccg
    29521 caggcccgct ccggcctccc cgagctcgac ctgctggccc tcttcgcccg ccaggcggct
    29581 acggccctgc gcgtggtctc ccccgatcct ccggcagacc tccccccgtc ccgtcgcgcg
    29641 gacgccctgc gcctcctcgg cagcctggaa caactcctgc gcgagccggc ctgacctgtg
    29701 tccgctgcac gccgacggcg tagggacgga ccatgggcca gctctgcgtg ccgatcattt
    29761 ccggacgttc ggtgggtgcg gtgccggcca gccctgcctg gctgcccggg cccgcctcgc
    29821 ccggctccag cgggccgacg ggccgttccg gaggaggacg gcccgccagt gctgtgaccg
    29881 cacaggcccg ccgggtcggt ggccggcacg gtcggagggg cggcgacgtc ggagccgact
    29941 gctgggcgtg cggtggccga gccttcacgg tgcgcgggct gaccgatgag gaaggacgga
    30001 ggcctgccgt gaacggtcag ccgggcgata cggggcagaa gacctccgtg cgcggtgtgg
    30061 agcccagaca cctccaccac cccggatgcc ttcgccgtga tcaatacccc tcggtgtcga
    30121 caacgctcgt tgtcgacact cctagctgta cggacgatcc gagggcccgc acgaggtgca
    30181 cgtctgtctg catacagcag tcggcgagga cgtgaggccg cgccagcgcc gccggcctac
    30241 gccctgatct cgtgagtccg ggaaagcggc gtcccgcgga gcgaggccga actcgcgacc
    30301 ggtccgcacc accaccgcgc cgggcgatgc ctgaccgtga ctgccgcccg cgtgcgtcgt
    30361 cgacgaggcc gtggatgaca ggcccacaga cgtcgaccgg ttccccccgg tggaggccac
    30421 gtcgtcggct cagtgtcgac gcggccgcgt cggggccgtc atgagaacac gctgatgccg
    30481 tagaggacga acacgaacaa gtgggccgcg ccatggatgg cggtgacgcg cctggcgctg
    30541 aacgtcgtga ggctcaagag caggctcacg ccgagcagca agaggttcgc cgggctctcg
    30601 gcgaggatca cggtctggtc ggtgagcagt ccgatggcga gcaccaccgg gagcgtgagc
    30661 ccgacgcagg agacgagcgc accgtgggcg aggttgctca cccgctgtgt ctctcccgtc
    30721 caggcggctc ggaccgtggt gatgccctcc gggaggaaca cgatgagagc gatgaggacg
    30781 cctgagaggg cgagcggcgc gccgagccgg tcgagcccgt cgtcgaggaa cgtc
//
